indomethacin has been researched along with Peptic Ulcer in 175 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of oral indomethacin on intragastric pH and serum gastrin were investigated in rheumatoid arthritis patients." | 9.07 | Effects of indomethacin on intragastric pH and meal-stimulated serum gastrin secretion in rheumatoid arthritis patients. ( Baak, LC; Dijkmans, BA; Jansen, JB; Janssen, M; Lamers, CB; Vandenbroucke, JP, 1993) |
| "Survival analysis techniques were used to compare the long-term incidence of peptic ulceration occurring in fenbufen, indomethacin and aspirin treated patients with a "background" incidence for the whole population." | 9.06 | A comparison of the incidence of peptic ulceration for fenbufen, indomethacin and aspirin treated patients compared with the general population. ( Cohen, PM, 1986) |
| " The anthocyanidin effects were examined in gastric ulcer mouse models induced by ethanol, non-steroidal anti-inflammatory drugs (NSAIDs), ischemia-reperfusion (IR), acetic acid and duodenal ulcer induced by polypharmacy." | 8.02 | Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation. ( Dos Santos, RC; Fagundes, FL; Pereira, QC; Zarricueta, ML, 2021) |
| " In the current work, we aimed to evaluate the gastro-protective effect of memantine in indomethacin-induced peptic ulcer in rats." | 7.91 | Gastroprotective effect of memantine in indomethacin-induced peptic ulcer in rats, a possible role for potassium channels. ( Gaber, SS; Rofaeil, RR, 2019) |
| " This study investigated the anti-ulcerogenic and antioxidant activities of aqueous extract of Carica papaya seed against indomethacin-induced peptic ulcer in male rats." | 7.81 | Anti-ulcerogenic activity of aqueous extract of Carica papaya seed on indomethacin-induced peptic ulcer in male albino rats. ( Adaja, MC; Ajiboye, TO; Oloyede, HO; Salawu, MO, 2015) |
| " Experimental gastric lesions were induced by water-immersion restraint stress, indomethacin and 80% ethanol in rats; whereas duodenal ulcers were produced by treatment of rats with cysteamine." | 7.69 | Effect of quinacrine, a phospholipase A2 inhibitor on stress and chemically induced gastroduodenal ulcers. ( Al Moutaery, AR; Tariq, M, 1997) |
| "The role of indomethacin-induced peptic ulceration in gastric acid secretion was investigated using albino rats of Wistar strain in early, mid and late pregnancy." | 7.68 | Role of indomethacin-induced peptic ulceration in gastric acid secretion in pregnant rats. ( Bolarinwa, Y; Evbuomwan, MI, 1993) |
| "A review has been made of the hospital case notes of 32 patients with indomethacin-associated peptic ulceration seen over a four year period in Dunedin." | 7.66 | Indomethacin-associated peptic ulceration. ( Heads, D; Maclaurin, BP; Richards, DA, 1978) |
| "Baicalin was 72% effective versus the reference drug and 80% effective against ethanol-induced ulcers." | 5.46 | Baicalin protects against gastroduodenal ulcers via the modulation of Nrf2 expression: Experimental, biochemical, and histological analyses. ( Meng, X; Yang, D; Zhang, T, 2017) |
| "The aim of this work was to prepare a combined drug dosage form of famotidine (FAM) and quercetin (QRT) to augment treatment of gastric ulcer." | 5.42 | Evaluation of combined famotidine with quercetin for the treatment of peptic ulcer: in vivo animal study. ( Abourehab, MA; Ahmed, OA; Khaled, KA; Sarhan, HA, 2015) |
| "Pretreatment with indomethacin caused a significant prolongation of ulcer healing, and this was accompanied by a significant reduction in PG and EGF formation, suggesting that both factors may be involved in ulcer healing." | 5.28 | Healing of chronic gastroduodenal ulcerations by antacids. Role of prostaglandins and epidermal growth factor. ( Brzozowski, T; Dembinski, A; Drozdowicz, D; Konturek, SJ; Nauert, C, 1990) |
| "The effects of oral indomethacin on intragastric pH and serum gastrin were investigated in rheumatoid arthritis patients." | 5.07 | Effects of indomethacin on intragastric pH and meal-stimulated serum gastrin secretion in rheumatoid arthritis patients. ( Baak, LC; Dijkmans, BA; Jansen, JB; Janssen, M; Lamers, CB; Vandenbroucke, JP, 1993) |
| "Survival analysis techniques were used to compare the long-term incidence of peptic ulceration occurring in fenbufen, indomethacin and aspirin treated patients with a "background" incidence for the whole population." | 5.06 | A comparison of the incidence of peptic ulceration for fenbufen, indomethacin and aspirin treated patients compared with the general population. ( Cohen, PM, 1986) |
| " The anthocyanidin effects were examined in gastric ulcer mouse models induced by ethanol, non-steroidal anti-inflammatory drugs (NSAIDs), ischemia-reperfusion (IR), acetic acid and duodenal ulcer induced by polypharmacy." | 4.02 | Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation. ( Dos Santos, RC; Fagundes, FL; Pereira, QC; Zarricueta, ML, 2021) |
| " In the current work, we aimed to evaluate the gastro-protective effect of memantine in indomethacin-induced peptic ulcer in rats." | 3.91 | Gastroprotective effect of memantine in indomethacin-induced peptic ulcer in rats, a possible role for potassium channels. ( Gaber, SS; Rofaeil, RR, 2019) |
| " This study investigated the anti-ulcerogenic and antioxidant activities of aqueous extract of Carica papaya seed against indomethacin-induced peptic ulcer in male rats." | 3.81 | Anti-ulcerogenic activity of aqueous extract of Carica papaya seed on indomethacin-induced peptic ulcer in male albino rats. ( Adaja, MC; Ajiboye, TO; Oloyede, HO; Salawu, MO, 2015) |
| " Pretreatment with Cyclea peltata extract provided significant protection against the peptic ulceration caused by ethanol administered individually, or in combination with indomethacin." | 3.75 | Gastric antisecretory and antiulcer activities of Cyclea peltata (Lam.) Hook. f. & Thoms. in rats. ( Anuja, GI; Latha, PG; Pradeep, S; Rajasekharan, S; Shine, VJ; Shyamal, S; Sini, S; Suja, SR, 2009) |
| " On the other hand, the non-selective NOS inhibitor L-NAME but not aminoguanidine (a relatively selective inhibitor of iNOS), significantly potentiated the acid secretory and mucosal ulcerogenic responses in the stomach but reduced the duodenal damage in response to hypothermia, the effects being antagonized by co-administration of L-arginine." | 3.70 | Roles of endogenous prostaglandins and nitric oxide in gastroduodenal ulcerogenic responses induced in rats by hypothermic stress. ( Araki, H; Mizoguchi, H; Sugamoto, S; Suzuki, K; Takeuchi, K; Umdeda, M, 1999) |
| " Experimental gastric lesions were induced by water-immersion restraint stress, indomethacin and 80% ethanol in rats; whereas duodenal ulcers were produced by treatment of rats with cysteamine." | 3.69 | Effect of quinacrine, a phospholipase A2 inhibitor on stress and chemically induced gastroduodenal ulcers. ( Al Moutaery, AR; Tariq, M, 1997) |
| "The role of indomethacin-induced peptic ulceration in gastric acid secretion was investigated using albino rats of Wistar strain in early, mid and late pregnancy." | 3.68 | Role of indomethacin-induced peptic ulceration in gastric acid secretion in pregnant rats. ( Bolarinwa, Y; Evbuomwan, MI, 1993) |
| " FCE 20700 was more potent than PGE2 in the prevention of stress-induced gastric ulcers (ED50 = 262 and 787 mcg/kg) and indomethacin-induced intestinal ulcers (ED50 = 557 and 4569 mcg/kg), and showed the same potency as PGE2 in the prevention of ethanol (ED50 = 9." | 3.67 | Cytoprotective and antisecretory effects of 11-deoxy-13,14-didehydro-16(s)-methyl PGE2 methylester (FCE 20700). ( Arrigoni, C; Ceserani, R; Faustini, F; Mizzotti, B; Toti, D, 1984) |
| " The topical application of NSAID ointment (1% of indomethacin, ketoprofen or diclofenac sodium) markedly inhibited the paw edema by carrageenin in rats." | 3.66 | [Evaluation of nonsteroidal anti-inflammatory drugs (NSAID) intended for use as topical anti-inflammatory drugs]. ( Kyuki, K, 1982) |
| "A review has been made of the hospital case notes of 32 patients with indomethacin-associated peptic ulceration seen over a four year period in Dunedin." | 3.66 | Indomethacin-associated peptic ulceration. ( Heads, D; Maclaurin, BP; Richards, DA, 1978) |
| " Some of the newer NSAIDs seem at normal dosage to be far less damaging than traditional ASA or indomethacin." | 2.37 | Gastroduodenal damage due to drugs, alcohol and smoking. ( Domschke, S; Domschke, W, 1984) |
| "Baicalin was 72% effective versus the reference drug and 80% effective against ethanol-induced ulcers." | 1.46 | Baicalin protects against gastroduodenal ulcers via the modulation of Nrf2 expression: Experimental, biochemical, and histological analyses. ( Meng, X; Yang, D; Zhang, T, 2017) |
| "The aim of this work was to prepare a combined drug dosage form of famotidine (FAM) and quercetin (QRT) to augment treatment of gastric ulcer." | 1.42 | Evaluation of combined famotidine with quercetin for the treatment of peptic ulcer: in vivo animal study. ( Abourehab, MA; Ahmed, OA; Khaled, KA; Sarhan, HA, 2015) |
| "Indomethacin (10 mg/kg) was administered subcutaneously to male Wistar rats to induce small intestinal damage and the severity of the intestinal injury was evaluated by measuring the area of visible ulcerative lesions." | 1.38 | Hemopexin is upregulated in rat intestinal mucosa injured by indomethacin. ( Handa, O; Hirai, Y; Ichikawa, H; Ishikawa, T; Kamada, K; Katada, K; Kokura, S; Konishi, H; Mizushima, K; Naito, Y; Okada, H; Oya-Ito, T; Takagi, T; Takaoka, M; Uchiyama, K; Yagi, N; Yamada, S; Yoshida, N; Yoshikawa, T, 2012) |
| "Indomethacin (10 mg/kg) was subcutaneously administered to induce small-intestinal damage." | 1.37 | Reduced small-intestinal injury induced by indomethacin in interleukin-17A-deficient mice. ( Fukumoto, K; Handa, O; Harusato, A; Hirai, Y; Horie, R; Inoue, K; Ishikawa, T; Kita, M; Kokura, S; Konishi, H; Mizushima, K; Naito, Y; Takagi, T; Uchiyama, K; Wakabayashi, N; Yagi, N; Yamada, S; Yoshida, N; Yoshikawa, T, 2011) |
| " Dosage of gastric reduced glutathione (GSH) levels showed that ethanol and indomethacin reduced the content of non-protein sulfhydryl (NP-SH) groups, while (-)-alpha-bisabolol significantly decreased the reduction of these levels on ulcer-induced mice, but not in mice without ulcer." | 1.36 | Gastroprotection of (-)-alpha-bisabolol on acute gastric mucosal lesions in mice: the possible involved pharmacological mechanisms. ( Aquino Neto, MR; de França Fonteles, MM; de Sousa, DP; de Sousa, FC; Gomes Silva, MI; Mendes Vasconcelos, SM; Moura Rocha, NF; Moura, BA; Vasconcelos Rios, ER; Venâncio, ET, 2010) |
| " Following 4-h duration (acute) oral dosing of fasted male Wistar rats, 1." | 1.33 | Gastric and thymic assay of acute oral treatment of rats with nitric oxide esters of ibuprofen or indomethacin. ( Downing, JE; Ingram, MJ; Madden, JC; Rostron, C, 2005) |
| "Ileal Crohn's disease ulcers identified in surgical resection specimens (n=5) and indomethacin-induced lesions in the rat jejunum (n=6) were examined macroscopically and histologically." | 1.31 | Similarities between ileal Crohn's disease and indomethacin experimental jejunal ulcers in the rat. ( Anthony, A; Dhillon, AP; Pounder, RE; Wakefield, AJ, 2000) |
| "Melatonin was also highly effective in scavenging *OH generated in vitro by a Cu2+-ascorbate system." | 1.31 | Melatonin protects against stress-induced gastric lesions by scavenging the hydroxyl radical. ( Bandyopadhyay, D; Bandyopadhyay, U; Banerjee, RK; Biswas, K; Reiter, RJ, 2000) |
| "Melatonin was administered in three different doses of 5, 10 and 20 mg/kg, 30 minutes prior to the administration of indomethacin." | 1.31 | Effect of melatonin and beta-carotene on indomethacin induced gastric mucosal injury. ( Bhargava, VK; Garg, SK; Singh, P, 2002) |
| "are used for the treatment of peptic ulcers." | 1.30 | Effects of Cistus laurifolius L. flowers on gastric and duodenal lesions. ( Ergun, E; Gürbüz, I; Yeşilada, E, 1997) |
| "However, NSAIDs produce gastroduodenal ulcers in about 25% of users (often with bleeding and/or perforations) and delay ulcer healing, presumably by blocking prostaglandin synthesis from cyclooxygenase (COX)-1 and COX-2 (ref." | 1.30 | Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing. ( Itani, RM; Jones, MK; Levin, E; Peskar, BM; Sarfeh, IJ; Tarnawski, AS; Wang, H, 1999) |
| "Chlorpromazine did not inhibit lesions formed after combining indomethacin with insulin in a dose of 3 IU/kg." | 1.28 | Effect of chlorpromazine on ulcer formation by indomethacin in histamine- and insulin-stimulated rats. ( Kohút, A; Mirossay, L; Nicák, A, 1991) |
| "Pretreatment with indomethacin to suppress mucosal generation of prostaglandin or the removal of salivary glands to eliminate the endogenous source of epidermal growth factor failed to affect sucralfate-induced gastroprotection." | 1.28 | Role of acid milieu in the gastroprotective and ulcer-healing activity of sucralfate. ( Brzozowski, T; Drozdowicz, D; Garlicki, J; Konturek, SJ; Majka, J; Pytko-Polonczyk, J, 1991) |
| "Pretreatment with indomethacin caused a significant prolongation of ulcer healing, and this was accompanied by a significant reduction in PG and EGF formation, suggesting that both factors may be involved in ulcer healing." | 1.28 | Healing of chronic gastroduodenal ulcerations by antacids. Role of prostaglandins and epidermal growth factor. ( Brzozowski, T; Dembinski, A; Drozdowicz, D; Konturek, SJ; Nauert, C, 1990) |
| "Indomethacin treatment significantly decreased (p less than 0." | 1.27 | Towards the mechanism of protection against indomethacin induced gastro-intestinal ulceration by naloxone. ( Aulakh, BS; Chakravarti, RN; Dhaunsi, GS; Gupta, NM; Majumdar, S, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 88 (50.29) | 18.7374 |
| 1990's | 34 (19.43) | 18.2507 |
| 2000's | 28 (16.00) | 29.6817 |
| 2010's | 24 (13.71) | 24.3611 |
| 2020's | 1 (0.57) | 2.80 |
| Authors | Studies |
|---|---|
| Shimojima, Y | 1 |
| Shirai, T | 1 |
| Baba, T | 1 |
| Hayashi, H | 1 |
| Almansa, C | 1 |
| Alfón, J | 1 |
| de Arriba, AF | 1 |
| Cavalcanti, FL | 1 |
| Escamilla, I | 1 |
| Gómez, LA | 1 |
| Miralles, A | 1 |
| Soliva, R | 1 |
| Bartrolí, J | 1 |
| Carceller, E | 1 |
| Merlos, M | 1 |
| García-Rafanell, J | 1 |
| Jain, S | 1 |
| Tran, S | 1 |
| El Gendy, MA | 1 |
| Kashfi, K | 1 |
| Jurasz, P | 1 |
| Velázquez-Martínez, CA | 1 |
| Fagundes, FL | 1 |
| Pereira, QC | 1 |
| Zarricueta, ML | 1 |
| Dos Santos, RC | 1 |
| Xia, X | 1 |
| Chan, KF | 1 |
| Wong, GTY | 1 |
| Wang, P | 1 |
| Liu, L | 1 |
| Yeung, BPM | 1 |
| Ng, EKW | 1 |
| Lau, JYW | 1 |
| Chiu, PWY | 1 |
| Zhang, T | 1 |
| Yang, D | 1 |
| Meng, X | 1 |
| Rofaeil, RR | 1 |
| Gaber, SS | 1 |
| Morhardt, TL | 1 |
| Hayashi, A | 1 |
| Ochi, T | 2 |
| Quirós, M | 1 |
| Kitamoto, S | 1 |
| Nagao-Kitamoto, H | 1 |
| Kuffa, P | 1 |
| Atarashi, K | 1 |
| Honda, K | 1 |
| Kao, JY | 1 |
| Nusrat, A | 1 |
| Kamada, N | 1 |
| Yarushkina, NI | 1 |
| Sudalina, MN | 1 |
| Punin, YM | 1 |
| Filaretova, LP | 1 |
| Moustafa, YM | 1 |
| El-Azab, MF | 1 |
| Fouda, A | 1 |
| Hamdan, DI | 1 |
| Mahmoud, MF | 1 |
| Wink, M | 1 |
| El-Shazly, AM | 1 |
| Yamawaki, H | 1 |
| Mihara, H | 1 |
| Suzuki, N | 1 |
| Nishizono, H | 1 |
| Uchida, K | 1 |
| Watanabe, S | 1 |
| Tominaga, M | 1 |
| Sugiyama, T | 1 |
| Dhiyaaldeen, SM | 1 |
| Amin, ZA | 1 |
| Darvish, PH | 1 |
| Mustafa, IF | 1 |
| Jamil, MM | 1 |
| Rouhollahi, E | 1 |
| Abdulla, MA | 1 |
| Oloyede, HO | 1 |
| Adaja, MC | 1 |
| Ajiboye, TO | 1 |
| Salawu, MO | 1 |
| Abourehab, MA | 1 |
| Khaled, KA | 1 |
| Sarhan, HA | 1 |
| Ahmed, OA | 1 |
| Sugita, R | 1 |
| Kubota, K | 1 |
| Sugimoto, K | 1 |
| Tachida, Y | 1 |
| Shibayama, T | 1 |
| Kiho, T | 1 |
| Kawakami, K | 1 |
| Shimada, K | 1 |
| Sukul, A | 1 |
| Poddar, SK | 1 |
| Haque, S | 1 |
| Saha, SK | 1 |
| Das, SC | 1 |
| Al Mahmud, Z | 1 |
| Abdur Rahman, SM | 1 |
| Kvetina, J | 1 |
| Kunes, M | 1 |
| Bures, J | 1 |
| Kopacova, M | 1 |
| Tachecí, I | 1 |
| Spelda, S | 1 |
| Herout, V | 1 |
| Rejchrt, S | 1 |
| Kato, N | 1 |
| Mashita, Y | 1 |
| Kato, S | 3 |
| Mitsufuji, S | 1 |
| Yoshikawa, T | 4 |
| Takeuchi, K | 7 |
| Dutra, RC | 1 |
| Fava, MB | 1 |
| Alves, CC | 1 |
| Ferreira, AP | 1 |
| Barbosa, NR | 1 |
| Iwai, T | 1 |
| Ichikawa, T | 1 |
| Goso, Y | 1 |
| Ikezawa, T | 1 |
| Saegusa, Y | 1 |
| Okayasu, I | 1 |
| Saigenji, K | 1 |
| Ishihara, K | 1 |
| Shine, VJ | 1 |
| Latha, PG | 1 |
| Shyamal, S | 1 |
| Suja, SR | 1 |
| Anuja, GI | 1 |
| Sini, S | 1 |
| Pradeep, S | 1 |
| Rajasekharan, S | 1 |
| Asano, T | 1 |
| Tanaka, K | 1 |
| Yamakawa, N | 1 |
| Adachi, H | 1 |
| Sobue, G | 1 |
| Goto, H | 2 |
| Mizushima, T | 1 |
| Moura Rocha, NF | 1 |
| Venâncio, ET | 1 |
| Moura, BA | 1 |
| Gomes Silva, MI | 1 |
| Aquino Neto, MR | 1 |
| Vasconcelos Rios, ER | 1 |
| de Sousa, DP | 1 |
| Mendes Vasconcelos, SM | 1 |
| de França Fonteles, MM | 1 |
| de Sousa, FC | 1 |
| Kubo, Y | 1 |
| Kumano, A | 1 |
| Kamei, K | 1 |
| Amagase, K | 4 |
| Abe, N | 1 |
| Umegaki, E | 1 |
| Yoda, Y | 1 |
| Tokioka, S | 1 |
| Murano, M | 1 |
| Higuchi, K | 1 |
| Tanigami, M | 1 |
| Ochi, A | 1 |
| Okuda, S | 1 |
| Hatazawa, R | 1 |
| Yamada, S | 2 |
| Naito, Y | 3 |
| Takagi, T | 3 |
| Mizushima, K | 2 |
| Hirai, Y | 2 |
| Horie, R | 1 |
| Fukumoto, K | 1 |
| Inoue, K | 1 |
| Harusato, A | 1 |
| Yoshida, N | 3 |
| Uchiyama, K | 2 |
| Handa, O | 3 |
| Ishikawa, T | 2 |
| Konishi, H | 2 |
| Wakabayashi, N | 1 |
| Yagi, N | 2 |
| Kokura, S | 3 |
| Kita, M | 1 |
| Riaño, A | 1 |
| Ortiz-Masià, D | 1 |
| Velázquez, M | 1 |
| Calatayud, S | 1 |
| Esplugues, JV | 1 |
| Barrachina, MD | 1 |
| Whiteley, PE | 1 |
| Dalrymple, SA | 1 |
| Okada, H | 1 |
| Takaoka, M | 1 |
| Oya-Ito, T | 1 |
| Kamada, K | 1 |
| Katada, K | 1 |
| Ichikawa, H | 2 |
| Nadatani, Y | 1 |
| Watanabe, T | 1 |
| Tanigawa, T | 1 |
| Machida, H | 1 |
| Okazaki, H | 1 |
| Yamagami, H | 1 |
| Watanabe, K | 1 |
| Tominaga, K | 1 |
| Fujiwara, Y | 1 |
| Arakawa, T | 2 |
| Szabó, IL | 1 |
| Czimmer, J | 1 |
| Szolcsányi, J | 1 |
| Mózsik, G | 1 |
| Al-Rehaily, AJ | 1 |
| Al-Howiriny, TA | 1 |
| Al-Sohaibani, MO | 1 |
| Rafatullah, S | 1 |
| Singh, P | 1 |
| Bhargava, VK | 1 |
| Garg, SK | 1 |
| Tachibana, M | 1 |
| Inoue, N | 1 |
| Yoshida, E | 1 |
| Matsui, M | 1 |
| Ukai, Y | 1 |
| Yano, J | 1 |
| Petrovic, SD | 1 |
| Dobric, S | 1 |
| Bokonjic, D | 1 |
| Niketic, M | 1 |
| García-Piñeres, A | 1 |
| Merfort, I | 1 |
| Matsuda, H | 1 |
| Pongpiriyadacha, Y | 1 |
| Morikawa, T | 1 |
| Ochi, M | 1 |
| Yoshikawa, M | 1 |
| LOEVGREN, O | 1 |
| ALLANDER, E | 1 |
| BOYLE, AC | 1 |
| Takagi-Matsumoto, H | 1 |
| Ng, B | 1 |
| Tsukimi, Y | 1 |
| Tajimi, M | 1 |
| Mosina, LM | 1 |
| Vlasov, AP | 1 |
| Plotnikova, NA | 1 |
| Rodina, OP | 1 |
| Downing, JE | 1 |
| Madden, JC | 1 |
| Ingram, MJ | 1 |
| Rostron, C | 1 |
| Kim, JM | 1 |
| Choi, SM | 1 |
| Kim, DH | 1 |
| Oh, TY | 1 |
| Ahn, BO | 1 |
| Kwon, JW | 1 |
| Kim, WB | 1 |
| Bhatnagar, M | 1 |
| Sisodia, SS | 1 |
| Bhatnagar, R | 1 |
| Dalby, AB | 1 |
| Frank, DN | 1 |
| St Amand, AL | 1 |
| Bendele, AM | 1 |
| Pace, NR | 1 |
| Kamil, R | 1 |
| Geier, MS | 1 |
| Butler, RN | 1 |
| Howarth, GS | 1 |
| Tanaka, A | 1 |
| Aihara, E | 1 |
| Okuda, T | 1 |
| Menguy, R | 2 |
| Desbaillets, L | 1 |
| Robins, PG | 1 |
| Balint, GA | 4 |
| Varro, V | 4 |
| Kirk, RM | 1 |
| Maggauer, H | 1 |
| Meoni, S | 1 |
| Monaci, R | 1 |
| Náfrádi, J | 3 |
| Domschke, S | 1 |
| Domschke, W | 1 |
| Collier, DS | 1 |
| Pain, JA | 1 |
| Yokoyama, Y | 1 |
| Nakamura, H | 1 |
| Shimizu, M | 1 |
| Defilippi, C | 1 |
| Morales, A | 1 |
| Smok, G | 1 |
| Gonzalez, S | 1 |
| Angelo, S | 1 |
| Arrigoni, C | 1 |
| Mizzotti, B | 1 |
| Toti, D | 1 |
| Faustini, F | 1 |
| Ceserani, R | 1 |
| Sebestyén, G | 1 |
| Gergely, V | 1 |
| Virág, S | 1 |
| Mészáros, Z | 1 |
| Okabe, S | 4 |
| Pillay, SP | 1 |
| Hardie, IR | 1 |
| Burnett, W | 1 |
| Bunton, RW | 1 |
| Barrett, DC | 1 |
| Palmer, DG | 1 |
| Visconti, G | 1 |
| Spotti, D | 1 |
| Piperno, A | 1 |
| Marini, U | 1 |
| Trewby, PN | 1 |
| Satoh, H | 2 |
| Guth, PH | 1 |
| Grossman, MI | 1 |
| O'Brien, WM | 1 |
| Kyuki, K | 1 |
| Birnbaum, JE | 1 |
| Wilson, DE | 1 |
| Partridge, R | 1 |
| Scruggs, W | 1 |
| Sloboda, AE | 1 |
| Mourillon, S | 1 |
| Yamada, J | 1 |
| Ivey, KJ | 1 |
| Johansson, C | 1 |
| Kollberg, B | 1 |
| Nordemar, R | 1 |
| Samuelson, K | 1 |
| Bergström, S | 1 |
| Dubois, A | 1 |
| Isenberg, JI | 1 |
| Müller, P | 2 |
| Kather, H | 1 |
| Simon, B | 2 |
| Dammann, HG | 2 |
| Wolf, N | 1 |
| Burkhardt, F | 1 |
| Gaw, AJ | 1 |
| Williams, LV | 1 |
| Spraggs, CF | 1 |
| Jordan, CC | 1 |
| Okumura, T | 1 |
| Taylor, IL | 1 |
| Fukagawa, K | 1 |
| Tso, P | 1 |
| Pappas, TN | 1 |
| Evbuomwan, MI | 1 |
| Bolarinwa, Y | 1 |
| Laufer, S | 1 |
| Tries, S | 1 |
| Augustin, J | 1 |
| Elsässer, R | 1 |
| Algate, DR | 1 |
| Atterson, PR | 1 |
| Munt, PL | 1 |
| Janssen, M | 1 |
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| Anthony, A | 2 |
| Khan, K | 1 |
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| Schneider, HT | 1 |
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| Yamamoto, H | 1 |
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| Gürbüz, I | 1 |
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| Al Moutaery, AR | 2 |
| Tariq, M | 2 |
| Palop, D | 1 |
| Romero, A | 1 |
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| Savarino, V | 1 |
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| Caruso, I | 2 |
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14 reviews available for indomethacin and Peptic Ulcer
| Article | Year |
|---|---|
Prostaglandin EP receptors and their roles in mucosal protection and ulcer healing in the gastrointestinal tract.
Topics: Animals; Bicarbonates; Cytoprotection; Dinoprostone; Esophagus; Gastric Mucosa; Humans; Indomethacin | 2010 |
Molecular pharmacological approaches to effects of capsaicinoids and of classical antisecretory drugs on gastric basal acid secretion and on indomethacin-induced gastric mucosal damage in human healthy subjects (mini review).
Topics: Adult; Afferent Pathways; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Atrop | 2013 |
Gastroduodenal damage due to drugs, alcohol and smoking.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Ethanol; Gastric Mucosa; Gastrointestinal | 1984 |
[The most common drugs considered harmful to the stomach, Clinical and endoscopic studies].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Dyspepsia; Fema | 1980 |
Drug-induced peptic ulcer and upper gastrointestinal bleeding.
Topics: Adrenal Cortex Hormones; Alcoholism; Animals; Aspirin; Diuretics; Emepronium; Female; Gastrointestin | 1980 |
[Neutrophil-endothelium interaction].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cell Adhesion; Cell Adhesion Molecules; | 2002 |
[Mechanism of the ulcerogenic effects of phenylbutazone and indomethacin].
Topics: Adrenalectomy; Animals; Female; Gastric Juice; Gastric Mucosa; Guinea Pigs; Histidine Decarboxylase; | 1978 |
The role of the mucosal barrier in drug-induced gastric ulceration and erosions.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Ethanol; Gastric Juice; Gastric Mucosa; | 1976 |
Analgesics and the stomach.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Indometha | 1976 |
[Gastric mucosa barrier and the effect of non-steroidal anti-inflammatory agents and corticosteroid hormones on the gastric and duodenal mucosa].
Topics: Animals; Aspirin; Duodenum; Gastric Mucosa; Glucocorticoids; Humans; Indomethacin; Intestinal Mucosa | 1988 |
[Gastric mucin].
Topics: Aspirin; Epithelial Cells; Epithelium; Gastric Juice; Gastric Mucins; Gastric Mucosa; Glycoproteins; | 1972 |
Gastric mucus and the gastric mucous barrier. A review.
Topics: Adrenocorticotropic Hormone; Aspirin; Eating; Fasting; Gastric Mucosa; Gastritis; Histamine; Humans; | 1969 |
Effects of prostaglandins on the stomach and the intestine.
Topics: Adenylyl Cyclases; Administration, Oral; Animals; Cyclic AMP; Depression, Chemical; Dose-Response Re | 1974 |
Ibuprofen. A review.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials | 1971 |
8 trials available for indomethacin and Peptic Ulcer
| Article | Year |
|---|---|
Molecular pharmacological approaches to effects of capsaicinoids and of classical antisecretory drugs on gastric basal acid secretion and on indomethacin-induced gastric mucosal damage in human healthy subjects (mini review).
Topics: Adult; Afferent Pathways; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Atrop | 2013 |
Protective effect of prostaglandin E2 in the gastrointestinal tract during indomethacin treatment of rheumatic diseases.
Topics: Adult; Arthritis; Double-Blind Method; Erythrocytes; Evaluation Studies as Topic; Feces; Hemoglobins | 1980 |
[Effective prevention of indomethacin-induced gastroduodenal mucosal lesions with roxatidine acetate].
Topics: Adult; Cross-Over Studies; Histamine H2 Antagonists; Humans; Indomethacin; Male; Peptic Ulcer; Piper | 1995 |
Effects of indomethacin on intragastric pH and meal-stimulated serum gastrin secretion in rheumatoid arthritis patients.
Topics: Administration, Oral; Aged; Arthritis, Rheumatoid; Basal Metabolism; Double-Blind Method; Female; Fo | 1993 |
Prevention of gastroduodenal damage with omeprazole in patients receiving continuous NSAIDs treatment. A double blind placebo controlled study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diclofenac; Double-Blind Method; Endosco | 1998 |
A comparison of the incidence of peptic ulceration for fenbufen, indomethacin and aspirin treated patients compared with the general population.
Topics: Actuarial Analysis; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Humans; Indomethaci | 1986 |
[A comparative gastroscopic study of lonazolac and indomethacin in healthy subjects].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Double-Blind Method; Gastr | 1986 |
Ibuprofen. A review.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials | 1971 |
155 other studies available for indomethacin and Peptic Ulcer
| Article | Year |
|---|---|
1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Bacillus; Chromatography | 1985 |
Synthesis and structure-activity relationship of a new series of COX-2 selective inhibitors: 1,5-diarylimidazoles.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Binding Sites | 2003 |
Nitric oxide release is not required to decrease the ulcerogenic profile of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Cyclooxygenase 1; Cyclooxy | 2012 |
Malvidin Protects against and Repairs Peptic Ulcers in Mice by Alleviating Oxidative Stress and Inflammation.
Topics: Acetic Acid; Animals; Anthocyanins; Antioxidants; Biomarkers; Cyclooxygenase 1; Disease Models, Anim | 2021 |
Mesenchymal stem cells promote healing of nonsteroidal anti-inflammatory drug-related peptic ulcer through paracrine actions in pigs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Cell Transdifferentiation; Cul | 2019 |
Baicalin protects against gastroduodenal ulcers via the modulation of Nrf2 expression: Experimental, biochemical, and histological analyses.
Topics: Animals; Anti-Ulcer Agents; Blotting, Western; Cimetidine; Disease Models, Animal; Dose-Response Rel | 2017 |
Gastroprotective effect of memantine in indomethacin-induced peptic ulcer in rats, a possible role for potassium channels.
Topics: Animals; Anti-Ulcer Agents; Glyburide; Indomethacin; Male; Memantine; Nitric Oxide Synthase; Oxidati | 2019 |
IL-10 produced by macrophages regulates epithelial integrity in the small intestine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Female; Gastrointestinal M | 2019 |
Vulnerability of gastric and small intestinal mucosa to ulcerogenic action of indomethacin in C57/BL6/J mice and transient receptor potential channel vanilloid type 1 knockout mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Gastric Mucosa; Indomethacin; Intestina | 2018 |
15-PGDH inhibitors: the antiulcer effects of carbenoxolone, pioglitazone and verapamil in indomethacin induced peptic ulcer rats.
Topics: Animals; Anti-Ulcer Agents; Carbenoxolone; Gastric Acid; Gastric Mucosa; Hydroxyprostaglandin Dehydr | 2013 |
Effect of hesperidin and neohesperidin from bittersweet orange (Citrus aurantium var. bigaradia) peel on indomethacin-induced peptic ulcers in rats.
Topics: Animals; Citrus; Cyclooxygenase 2; Fruit; Gastric Mucosa; Glutathione; Hesperidin; Indomethacin; Mal | 2014 |
Role of transient receptor potential vanilloid 4 activation in indomethacin-induced intestinal damage.
Topics: Adult; Aged; Animals; Arachidonic Acid; Calcium Signaling; Cell Line; Disease Models, Animal; Electr | 2014 |
Protective effects of (1-(4-hydroxy-phenyl)-3-m-tolyl-propenone chalcone in indomethacin-induced gastric erosive damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Chalcones; Female; Gastric Muco | 2014 |
Anti-ulcerogenic activity of aqueous extract of Carica papaya seed on indomethacin-induced peptic ulcer in male albino rats.
Topics: Animals; Anti-Ulcer Agents; Carica; Disease Models, Animal; Dose-Response Relationship, Drug; Duoden | 2015 |
Evaluation of combined famotidine with quercetin for the treatment of peptic ulcer: in vivo animal study.
Topics: Alginates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Chemis | 2015 |
A novel selective prostaglandin E2 synthesis inhibitor relieves pyrexia and arthritis in Guinea pigs inflammatory models.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimen | 2016 |
Synthesis, Characterization and Comparison of Local Analgesic, Anti-Inflammatory, Anti-Ulcerogenic Activity of Copper and Zinc Complexes of Indomethacin.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Coordination Complexes; C | 2017 |
The use of wireless capsule enteroscopy in a preclinical study: a novel diagnostic tool for indomethacin-induced gastrointestinal injury in experimental pigs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Female; Gastric Mucosa; Gastros | 2008 |
Sildenafil, an inhibitor of phosphodiesterase subtype 5, prevents indomethacin-induced small-intestinal ulceration in rats via a NO/cGMP-dependent mechanism.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclic GMP; Enterobacteriaceae; Gastrointestinal C | 2009 |
Antiulcerogenic and anti-inflammatory activities of the essential oil from Pterodon emarginatus seeds.
Topics: Administration, Oral; Alkyl and Aryl Transferases; Animals; Anti-Inflammatory Agents; Anti-Ulcer Age | 2009 |
Effects of indomethacin on the rat small intestinal mucosa: immunohistochemical and biochemical studies using anti-mucin monoclonal antibodies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Ileum; Immunohistochemistr | 2009 |
Gastric antisecretory and antiulcer activities of Cyclea peltata (Lam.) Hook. f. & Thoms. in rats.
Topics: Animals; Anti-Ulcer Agents; Catalase; Cyclea; Disease Models, Animal; Ethanol; Gastric Juice; Gastri | 2009 |
HSP70 confers protection against indomethacin-induced lesions of the small intestine.
Topics: Animals; HSP70 Heat-Shock Proteins; Indomethacin; Intestine, Small; Mice; Mice, Inbred C57BL; Mice, | 2009 |
Gastroprotection of (-)-alpha-bisabolol on acute gastric mucosal lesions in mice: the possible involved pharmacological mechanisms.
Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastr | 2010 |
Urocortin prevents indomethacin-induced small intestinal lesions in rats through activation of CRF2 receptors.
Topics: Aniline Compounds; Animals; Bacterial Translocation; Corticotropin-Releasing Hormone; Cytoprotection | 2010 |
Protective effect of roxatidine against indomethacin-induced small intestinal mucosal injury in rats.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Disease Models, Animal; Famotidine; Histamine H2 Antagonists | 2010 |
Endogenous prostaglandin E2 accelerates healing of indomethacin-induced small intestinal lesions through upregulation of vascular endothelial growth factor expression by activation of EP4 receptors.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Disease M | 2010 |
Reduced small-intestinal injury induced by indomethacin in interleukin-17A-deficient mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CCL2; Chemokine CXCL1; Disease Models, A | 2011 |
Nitric oxide induces HIF-1α stabilization and expression of intestinal trefoil factor in the damaged rat jejunum and modulates ulcer healing.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Goblet Cells; Hypoxia-Inducible Factor 1, alpha Su | 2011 |
Models of inflammation: measuring gastrointestinal ulceration in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Female; Indomethacin; Infl | 2001 |
Hemopexin is upregulated in rat intestinal mucosa injured by indomethacin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Disease Models, Animal; Electro | 2012 |
High mobility group box 1 promotes small intestinal damage induced by nonsteroidal anti-inflammatory drugs through Toll-like receptor 4.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; HMGB1 Protein; Indomethacin; Inflammati | 2012 |
Gastroprotective effects of 'Amla' Emblica officinalis on in vivo test models in rats.
Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Ethanol; Female; Fruit; Gastric Mucosa; Indometh | 2002 |
Effect of melatonin and beta-carotene on indomethacin induced gastric mucosal injury.
Topics: Animals; Antioxidants; beta Carotene; Gastric Mucosa; Indomethacin; Male; Melatonin; Peptic Ulcer; R | 2002 |
Anti-inflammatory effect and low ulcerogenic activity of etodolac, a cyclooxygenase-2 selective non-steroidal anti-inflammatory drug, on adjuvant-induced arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cyclooxygenase Inhibitors; Diclofenac; | 2003 |
Evaluation of Tanacetum larvatum for an anti-inflammatory activity and for the protection against indomethacin-induced ulcerogenesis in rats.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; DNA; Edema; Hindlimb; Humans; Indomethacin; Jurkat C | 2003 |
Gastroprotective effects of phenylpropanoids from the rhizomes of Alpinia galanga in rats: structural requirements and mode of action.
Topics: Administration, Oral; Alpinia; Animals; Aspirin; Benzyl Alcohols; Drugs, Chinese Herbal; Ethanol; Et | 2003 |
INDOMETHACIN AND PEPTIC ULCER.
Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antipyretics; Drug Therapy; Indoles; | 1965 |
INDOMETHACIN AND PEPTIC ULCER.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Drug Therapy; Indoles; Indomethacin; Peptic Ulce | 1965 |
Effects of NSAIDs on bladder function in normal and cystitis rats: a comparison study of aspirin, indomethacin, and ketoprofen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclophosphamide; Cystitis; Female; Gastr | 2004 |
[Experimental assessment of the effect of dimephosphone on ulcerogenesis].
Topics: Animals; Antioxidants; Catalase; Disease Models, Animal; Gastric Mucosa; Indomethacin; Intestine, Sm | 2004 |
Gastric and thymic assay of acute oral treatment of rats with nitric oxide esters of ibuprofen or indomethacin.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Esterification; Gastric Muco | 2005 |
Combined use of omeprazole and a novel antioxidative cytoprotectant for the treatment of peptic ulcer. Facilitation of ulcer healing in experimental animals.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Arte | 2005 |
Antiulcer and antioxidant activity of Asparagus racemosus Willd and Withania somnifera Dunal in rats.
Topics: Animals; Antioxidants; Asparagus Plant; Catalase; Female; Gastrointestinal Contents; Indomethacin; L | 2005 |
Culture-independent analysis of indomethacin-induced alterations in the rat gastrointestinal microbiota.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ecosystem; Enterococcus faecalis; Female; Gastroin | 2006 |
Lactobacillus rhamnosus GG exacerbates intestinal ulceration in a model of indomethacin-induced enteropathy.
Topics: Animals; Apoptosis; Bifidobacterium; Cell Proliferation; Disease Models, Animal; Indomethacin; Intes | 2007 |
Effect of (S)-4-(1-(5-chloro-2-(4-fluorophenyoxy)benzamido)ethyl) benzoic acid (CJ-42794), a selective antagonist of prostaglandin E receptor subtype 4, on ulcerogenic and healing responses in rat gastrointestinal mucosa.
Topics: Animals; Benzamides; Benzoates; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Lactones; Peptic Ul | 2007 |
CV-11974, angiotensin II type I receptor antagonist, reduces the severity of indomethacin-induced rat enteritis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzimida | 2008 |
Role of inhibition of gastric mucous secretion in the phenomenon of gastric mucosal injury by indomethacin.
Topics: Animals; Dogs; Fucose; Gastric Mucins; Gastric Mucosa; Hexosamines; Indomethacin; Neuraminic Acids; | 1967 |
Gastrointestinal erosions and the lack of inflammatory response.
Topics: Animals; Aspirin; Chemotactic Factors; Gastric Mucosa; Gastroenteritis; Indomethacin; Intestinal Muc | 1980 |
Actinomycin inhibits gastric mucosal protection by prostacyclin in rats.
Topics: Animals; Dactinomycin; Epoprostenol; Female; Gastric Mucosa; Indomethacin; Peptic Ulcer; Prostagland | 1981 |
Factors determining the site of chronic gastroduodenal ulcers.
Topics: Animals; Aspirin; Chronic Disease; Diet; Digestive System; Duodenum; Gastric Acid; Gastric Mucins; G | 1982 |
[Pathophysiology of peptic ulcer].
Topics: Aspirin; Bile Acids and Salts; Gastric Acid; Gastric Emptying; Gastric Inhibitory Polypeptide; Gastr | 1983 |
[Prostaglandins, indomethacin and the physiopathology of various systems].
Topics: Cardiovascular System; Coronary Disease; Drug Interactions; Humans; Indomethacin; Inflammation; Kidn | 1984 |
The effect of naloxone in different gastroduodenal ulcer models.
Topics: Animals; Cysteamine; Disease Models, Animal; Female; Gastric Mucosa; Indomethacin; Male; Naloxone; P | 1983 |
Rectal indomethacin for control of postoperative pain.
Topics: Humans; Indomethacin; Pain, Postoperative; Peptic Ulcer; Suppositories | 1983 |
Gastrointestinal ulcerogenic activity of tolmetin sodium in rats in comparison with those of indomethacin and aspirin.
Topics: Animals; Aspirin; Indomethacin; Male; Peptic Ulcer; Pyrroles; Rats; Rats, Inbred Strains; Tolmetin | 1984 |
[Experimental ulcer induced by indomethacin in the dog. Morphofunctional changes during its course].
Topics: Animals; Dogs; Gastric Mucosa; Gastrointestinal Motility; Indomethacin; Manometry; Peptic Ulcer; Pre | 1984 |
Cytoprotective and antisecretory effects of 11-deoxy-13,14-didehydro-16(s)-methyl PGE2 methylester (FCE 20700).
Topics: Animals; Anti-Ulcer Agents; Diarrhea; Dinoprostone; Ethanol; Gastric Juice; Indomethacin; Intestines | 1984 |
Investigation of the interaction between Probon and indomethacin in rats.
Topics: Animals; Antipyrine; Drug Interactions; Drug Therapy, Combination; Female; Indomethacin; Male; Pepti | 1983 |
[Experimental models for peptic ulcer].
Topics: Animals; Aspirin; Disease Models, Animal; Dogs; Histamine; Immersion; Indomethacin; Peptic Ulcer; Ra | 1984 |
Emergency surgery for the complications of peptic ulcer in the elderly.
Topics: Aged; Emergencies; Heart Failure; Humans; Indomethacin; Lung Diseases, Obstructive; Peptic Ulcer; Sa | 1981 |
Reintroduction of anti-inflammatory drug therapy after drug-associated gastro-intestinal disturbances.
Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Arthritis; Duodenal Ulcer; Female; Gastrointes | 1982 |
Role of food in gastrointestinal ulceration produced by indomethacin in the rat.
Topics: Animals; Diet; Disease Models, Animal; Feeding Behavior; Female; Food; Indomethacin; Intestine, Smal | 1982 |
Ulcerogenic properties of anti-inflammatory drugs.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Humans; Indometha | 1982 |
[Evaluation of nonsteroidal anti-inflammatory drugs (NSAID) intended for use as topical anti-inflammatory drugs].
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dose-Response R | 1982 |
A new prostaglandin E1 analogue (CL115,574). I. antisecretory and cytoprotective effects in the rat.
Topics: Alprostadil; Animals; Cimetidine; Gastric Acid; Hematocrit; Indomethacin; Intestinal Mucosa; Male; P | 1981 |
[Scanning electron microscopic studies on the experimental ulcer of the rat small intestine. [2] Ultrastructural observation on the small intestinal ulcer induced by indomethacin (author's transl)].
Topics: Animals; Indomethacin; Intestine, Small; Male; Microscopy, Electron, Scanning; Peptic Ulcer; Rats; R | 1981 |
Drugs, gastritis, and peptic ulcer.
Topics: Acetaminophen; Animals; Aspirin; Bicarbonates; Cimetidine; Duodenitis; Gastric Acid; Gastric Mucosa; | 1981 |
E prostaglandins and the stomach: pathophysiological mediators or therapeutic agents?
Topics: Animals; Gastric Juice; Humans; Indomethacin; Pentagastrin; Peptic Ulcer; Prostaglandins E; Stomach | 1980 |
Peptic ulcer: epidemiology, nutritional aspects, drugs, smoking, alcohol, and diet.
Topics: Adrenal Cortex Hormones; Alcoholic Beverages; Aspirin; Feeding Behavior; Gastric Mucosa; Hormones; H | 1980 |
[Cytoprotection: a new principle in ulcer therapy?].
Topics: Aspirin; Carbenoxolone; Cimetidine; Gastric Mucosa; Humans; Indomethacin; Peptic Ulcer; Prostaglandi | 1980 |
Role of pepsin in the development of indomethacin-induced antral ulceration in the rat.
Topics: Animals; Disease Models, Animal; Drug Interactions; Female; Gastric Mucosa; Indomethacin; Methylcell | 1995 |
Apolipoprotein A-IV acts centrally in the brain to reduce the severity of gastric ulceration in the rat.
Topics: Animals; Apolipoproteins A; Brain; Deoxyglucose; Dose-Response Relationship, Drug; Indomethacin; Inj | 1995 |
Role of indomethacin-induced peptic ulceration in gastric acid secretion in pregnant rats.
Topics: Animals; Carbachol; Disease Models, Animal; Female; Gastric Acid; Histamine; Indomethacin; Peptic Ul | 1993 |
Gastrointestinal tolerance of [2,2-dimethyl-6-(4-chlorophenyl-7-phenyl- 2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid in the rat.
Topics: Acetates; Animals; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Lipoxygenase Inhibitors; Male; P | 1994 |
Effect of NS-398, a new nonsteroidal anti-inflammatory agent, on gastric ulceration and acid secretion in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, | 1993 |
Comparative evaluation of ulcer prevention efficacy of orally, rectally and sublingually administered omeprazole in three acute gastric ulcer models in rats.
Topics: Administration, Oral; Administration, Rectal; Administration, Sublingual; Animals; Aspirin; Female; | 1993 |
Intestinal site-dependent susceptibility to chronic indomethacin in the rat: a morphological and biochemical study.
Topics: Animals; Colon; Digestive System; Dinoprostone; Gastric Mucosa; Indomethacin; Leukotriene B4; Male; | 1995 |
Distribution of extracellular matrix proteins in indomethacin-induced lesions in the rat stomach.
Topics: Animals; Extracellular Matrix Proteins; Fibronectins; Gastric Mucosa; Immunohistochemistry; Indometh | 1995 |
Effects of the novel histamine H2-receptor antagonist (+/-)-(E)-1-[2-hydroxy-2-(4-hydroxyphenyl)ethyl]-3-[2-[[[5- (methylamino)methyl-2-furyl]methyl]thio]ethyl]-2-(methylsulfonyl) guanidine on gastric secretion and gastroduodenal ulcers in rats.
Topics: Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Epirizole; Gastric Acid; Gastric Mucos | 1996 |
Effects of Cistus laurifolius L. flowers on gastric and duodenal lesions.
Topics: Animals; Anti-Ulcer Agents; Cysteamine; Disease Models, Animal; Ethanol; Female; Gastric Acid; Indom | 1997 |
Effect of quinacrine, a phospholipase A2 inhibitor on stress and chemically induced gastroduodenal ulcers.
Topics: Animals; Cyclooxygenase Inhibitors; Cysteamine; Duodenal Ulcer; Enzyme Inhibitors; Ethanol; Female; | 1997 |
Effect of ebrotidine on ethanol-induced gastric mucosal damage in the rat. Comparative study with other H2-receptor antagonists.
Topics: Animals; Benzenesulfonates; Cimetidine; Dose-Response Relationship, Drug; Ethanol; Famotidine; Femal | 1997 |
Gastric anti-ulcer and cytoprotective effect of l-serine in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Caustics; Dose-Response Relatio | 1997 |
Effect of one-month treatment with nonsteroidal antiinflammatory drugs (NSAIDs) on gastric pH of rheumatoid arthritis patients.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Case-Control S | 1998 |
Nonsteroidal anti-inflammatory drugs may delay the repair of gastric mucosa by suppressing prostaglandin-mediated increase of hepatocyte growth factor production.
Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Cholera Toxin; Cyclic AMP; Cyclooxygenase 1; C | 1998 |
Biochemical and pharmacological properties of a new proton pump inhibitor, 2-amino-4,5-dihydropyrido[1,2-a]thiazolo [5,4-g] benzimidazole (YJA20379-5).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Benzimidazoles; Epirizole; Etha | 1998 |
New model of cytoprotection/adaptive cytoprotection in rats: endogenous small irritants, antiulcer agents and indomethacin.
Topics: Amino Acid Sequence; Anastomosis, Surgical; Animals; Anti-Ulcer Agents; Atropine; Cyclooxygenase Inh | 1999 |
Anti-inflammatory and analgesic effects of a novel pyrazole derivative, FR140423.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cycloox | 1999 |
Expression of NOS II and its role in experimental small bowel ulceration in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Base Sequence; Disease Models, Animal; DNA Primers | 1999 |
Potassium channel modulators and indomethacin-induced gastric ulceration in rats.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Diazoxide; En | 1999 |
Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase | 1999 |
Gastroprotective effect from Calophyllum brasiliense Camb. bark on experimental gastric lesions in rats and mice.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Ethanol; Gastric | 1999 |
Similarities between ileal Crohn's disease and indomethacin experimental jejunal ulcers in the rat.
Topics: Animals; Crohn Disease; Humans; Ileum; Indomethacin; Intestine, Small; Jejunal Diseases; Male; Mesen | 2000 |
Roles of endogenous prostaglandins and nitric oxide in gastroduodenal ulcerogenic responses induced in rats by hypothermic stress.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Atropine; Cyclooxygenase Inhibi | 1999 |
Melatonin protects against stress-induced gastric lesions by scavenging the hydroxyl radical.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Cold Temperature; Dose-Response Relationship, Drug; Free R | 2000 |
Involvement of cyclooxygenase (COX)-2 products in acceleration of ulcer healing by gastrin and hepatocyte growth factor.
Topics: Animals; Antibodies; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibit | 2000 |
Gastroprotective effect of aparisthman, a diterpene isolated from Aparisthmium cordatum, on experimental gastric ulcer models in rats and mice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulce | 2001 |
The antiulcer activity of Garcinia cambogia extract against indomethacin-induced gastric ulcer in rats.
Topics: Animals; Anti-Ulcer Agents; Fruit; Garcinia cambogia; Gastric Acidity Determination; Gastric Mucosa; | 2002 |
[Experimental ulcer].
Topics: Animals; Caffeine; Cats; Cattle; Chickens; Disease Models, Animal; Dogs; Ducks; Guinea Pigs; Haplorh | 1975 |
Antagonism of the gastrointestinal ulcerogenic effect of some nonsteroidal anti-inflammatory agents by sodium salicylate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Dose-Response Relationship, Dru | 1976 |
The role of copper in preventing gastrointestinal damage by acidic anti-inflammatory drugs.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chelating Agents; Copper; Edema | 1976 |
Indomethacin-associated peptic ulceration.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; | 1978 |
Comparative pharmacology of a 1:10 combination of indomethacin-sodium salicylate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Castor Oil; Diarrhea; Ede | 1979 |
Pathophysiologic considerations in peptic ulcer disease.
Topics: ABO Blood-Group System; Adrenal Cortex Hormones; Aspirin; Bicarbonates; Environment; Female; Gastric | 1979 |
The role of direct tissue contact in the production of gastrointestinal ulcers by anti-inflammatory drugs in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Female; Ibuprofen; Indomethacin; Injections | 1979 |
Further investigations of indomethacin and intestinal ulcers in the rat.
Topics: Animals; Bile; Chenodeoxycholic Acid; Eating; Female; Indomethacin; Male; Peptic Ulcer; Rats; Stomac | 1978 |
[Prostaglandins and gastrointestinal functions (author's transl)].
Topics: Animals; Colchicine; Digestive System; Double-Blind Method; Humans; Indomethacin; Intestinal Absorpt | 1978 |
[Gastrointestinal diseases caused by drugs, especially by anti-inflammatory agents].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Betamethasone; Dogs; Gastrointestinal Diseases; Indometh | 1978 |
Resistance of the guinea pig to indomethacin ulcerogenesis.
Topics: Animals; Drug Resistance; Duodenal Ulcer; Guinea Pigs; Indomethacin; Lethal Dose 50; Male; Peptic Ul | 1978 |
Aspirin and newer anti-inflammatory agents in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Indomethaci | 1977 |
Protective dietary factors in experimental ulceration--study of some Nigerian cereals and tubers.
Topics: Animals; Diet; Dietary Carbohydrates; Edible Grain; Female; Humans; Indomethacin; Male; Nigeria; Pep | 1976 |
[Gastrointestinal hemorrhage caused by side effect of drugs].
Topics: Adult; Aged; Aspirin; Butadienes; Drug-Related Side Effects and Adverse Reactions; Female; Humans; I | 1976 |
Risk of ulceration with long-term indomethacin: endoscopic and histological changes in upper gastro-intestinal mucosa.
Topics: Arthritis, Rheumatoid; Biopsy; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Humans; Indometh | 1992 |
Effects of gonadectomy on indomethacin-induced ulceration and peptic activity in rats.
Topics: Animals; Estrogens; Estrus; Female; Gastric Acid; Gastric Mucins; Indomethacin; Male; Orchiectomy; O | 1990 |
Effect of chlorpromazine on ulcer formation by indomethacin in histamine- and insulin-stimulated rats.
Topics: Animals; Anti-Ulcer Agents; Chlorpromazine; Gastric Acid; Gastric Mucosa; Histamine; Indomethacin; I | 1991 |
Role of acid milieu in the gastroprotective and ulcer-healing activity of sucralfate.
Topics: Animals; Chronic Disease; Combined Modality Therapy; Disease Models, Animal; Drug Therapy, Combinati | 1991 |
[Clinical problems in the treatment and physiopathology of drug-induced peptic ulcers].
Topics: Animals; Endothelins; Endothelium, Vascular; Ethanol; Gastric Mucosa; Indomethacin; Ischemia; Male; | 1991 |
Histo-chemical studies on the anti-ulcer effect of bamboo grass in rats.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Cell Membrane; Ethanol; Gastric Mucosa; Glycosamin | 1990 |
On the possible role of different endogenous opiate receptors in gastroduodenal ulceration of the rat.
Topics: Animals; Cysteamine; Female; Indomethacin; Male; Morphine; Nalorphine; Naloxone; Peptic Ulcer; Rats; | 1990 |
Healing of chronic gastroduodenal ulcerations by antacids. Role of prostaglandins and epidermal growth factor.
Topics: Aluminum Hydroxide; Animals; Antacids; Drug Combinations; Epidermal Growth Factor; Hydrogen-Ion Conc | 1990 |
Protective effect of dimethylsulphoxide in stress- and indometacin-induced gastrointestinal ulceration in rats.
Topics: Animals; Dimethyl Sulfoxide; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Male; Peptic Ulcer; Ra | 1989 |
No correlation between indomethacin-induced gastroduodenal damage and inhibition of gastric prostanoid synthesis.
Topics: Adolescent; Adult; Aged; Duodenum; Female; Gastric Mucosa; Humans; Indomethacin; Intestinal Mucosa; | 1988 |
Biochemical and pharmacological analysis of 2-[(2-dimethylaminobenzyl)sulfinyl] benzimidazole (NC-1300), a new proton pump inhibitor.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetylcholine; Adenosine Triphosphatases; Animals; Anti-Ulc | 1986 |
Sucralfate protection against gastrointestinal damage: possible role of prostanoids.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Gastri | 1986 |
Effects of prostaglandin D2 and omeprazole on indomethacin-induced gastric ulcers in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Gastric Acid; Gastric Mucosa; Indomethacin; Male; Ome | 1988 |
Protection of isolated rat gastric cells by prostaglandins from damage caused by ethanol. Preliminary report.
Topics: Animals; Dinoprostone; Epithelium; Ethanol; Gastric Mucosa; Indomethacin; Male; Peptic Ulcer; Prosta | 1988 |
Time-course study of gastric damages in rats by anti-inflammatory drugs using a gastroscope and its quantification.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Fenoprofen; Gastric Mucosa; Gastrointesti | 1988 |
Towards the mechanism of protection against indomethacin induced gastro-intestinal ulceration by naloxone.
Topics: Animals; Hydrolases; Indomethacin; Intestinal Mucosa; Lysosomes; Male; Naloxone; Peptic Ulcer; Rats; | 1988 |
Oxygen free radicals interact with indomethacin to cause gastrointestinal injury.
Topics: Animals; Anti-Inflammatory Agents; Butylated Hydroxytoluene; Digestive System; Dinoprostone; Ethanol | 1986 |
Eicosanoids and the gastrointestinal tract: promising but no verdict yet.
Topics: Biliary Tract Diseases; Colitis, Ulcerative; Digestive System; Eicosanoic Acids; Epoprostenol; Human | 1986 |
Changes of endogenous prostacyclin-level in different experimental gastroduodenal ulcer models of rat.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cysteamine; Epoprostenol; Female; Gastric Mucosa; Indomethaci | 1986 |
Efficacy of sucralfate in preventing peptic ulceration induced by nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Indomethacin; Male; Peptic Ulcer; Rats; S | 1987 |
Effect of vegetable banana powder on changes induced by ulcerogenic agents in dissolved mucosubstances of gastric juice.
Topics: Animals; Aspirin; Carbohydrates; Female; Fruit; Gastric Juice; Indomethacin; Male; Peptic Ulcer; Phe | 1985 |
[Gastroduodenal ulcer: pathogenetic and clinical aspects].
Topics: Alcoholic Beverages; Diet; Duodenal Ulcer; Gastric Juice; Gastrins; Gastrointestinal Hormones; Hista | 1974 |
Letter: Ulcerogenic potential of indomethacin in arthritic and non-arthritic rats.
Topics: Animals; Arthritis, Infectious; Body Weight; Indomethacin; Male; Mycobacterium Infections; Peptic Ul | 1973 |
2-(2,4-dichlorophenoxy) phenylacetic acid (fenclofenac): one of a novel series of anti-inflammatory compounds with low ulcerogenic potential.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; Disease Mod | 1974 |
Pharmacology of zolimidine (2-(p-methylsulfonylphenyl)-imidazo (1,2-a) pyridine) a new non-anticholinergic gastroprotective agent. IV) Enhancement of gastric mucus production in different experimental models.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Cold Temperature; Gastric Mucins; Gastric Mu | 1974 |
[Undesired collateral effects of antirheumatic drugs: indomethacin].
Topics: Arthritis, Rheumatoid; Drug Eruptions; Gastrointestinal Diseases; Headache; Humans; Indomethacin; Pa | 1972 |
Blockade of catatoxic steroid actions by metyrapone.
Topics: Adrenocorticotropic Hormone; Animals; Digitoxin; Female; Indomethacin; Metyrapone; Peptic Ulcer; Rat | 1970 |
[Side effects of drugs. 2. Gastrointestinal side effects].
Topics: Adrenocorticotropic Hormone; Caffeine; Drug-Related Side Effects and Adverse Reactions; Gastrointest | 1969 |
Iatrogenic gastrointestinal diseases in the aged.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aged; Cathartics; Chemical and Drug Induced Li | 1972 |
General pharmacological properties of 4,5-diphenyl-2-bis-(2-hydroxyethyl)-aminoxazol (ditazol).
Topics: Amphetamine; Animals; Anti-Inflammatory Agents; Atropine; Blood Pressure; Cats; Chlorpromazine; Etha | 1973 |
Upper gastrointestinal disease in rheumatoid arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Arizona; Arthritis, Rheumatoid; Aspir | 1974 |
Inhibition of indomethacin-induced gastric ulceration in the rat by perorally-administered synthetic and natural prostaglandin analogues.
Topics: Animals; Depression, Chemical; Gastric Juice; Indomethacin; Male; Peptic Ulcer; Propantheline; Prost | 1974 |
[Complications and problems of total arthroplasty of the hip joint].
Topics: Acrylates; Biomechanical Phenomena; Calcinosis; Embolism; Femoral Fractures; Hip; Humans; Indomethac | 1972 |
Pharmacological investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 7. Pharmacological comparison with standard anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Benzyl Compounds; Edema; Female; Fever; Flufenamic Acid; Indometh | 1972 |
[Experiences with indomethacin in long-term therapy of juvenile rheumatoid arthritis].
Topics: Adolescent; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Child, Preschool; Drug Synergism; Glu | 1971 |
Prevention of indomethacin-induced intestinal ulcers by spironolactone and norbolethone.
Topics: Anabolic Agents; Animals; Digestive System; Female; Indomethacin; Peptic Ulcer; Peritonitis; Rats; S | 1969 |
[Current analgesic anti-inflammatory drugs].
Topics: Analgesics; Aniline Compounds; Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver In | 1970 |
Effects of drugs, ileal obstruction, and irradiation on rat gastrointestinal propulsion.
Topics: Animals; Chlorisondamine; Chlorpromazine; Chromium Isotopes; Fasting; Gastrointestinal Motility; Ile | 1970 |
Indomethacin-induced intestinal lesions in the rat.
Topics: Administration, Oral; Animals; Antacids; Aspirin; Atropine; Bile Ducts; Bretylium Compounds; Chlorpr | 1970 |
Anti-inflammatory and analgesic properties of clonixin (2-(2' methyl-3' chloro anilino) nicotinic acid).
Topics: Analgesics; Aniline Compounds; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Flufenamic Aci | 1971 |
Small intestinal ulcers and intestinal flora in rats given indomethacin.
Topics: Animals; Anti-Bacterial Agents; Cecal Diseases; Ileum; Indomethacin; Intestinal Diseases; Intestine, | 1969 |