indomethacin has been researched along with Peptic Ulcer Perforation in 19 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Peptic Ulcer Perforation: Penetration of a PEPTIC ULCER through the wall of DUODENUM or STOMACH allowing the leakage of luminal contents into the PERITONEAL CAVITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Indomethacin treatment precipitated gastric ulceration, which led to the formation of a gastro-colic fistula." | 3.66 | Gastro-colic fistula secondary to benign gastric ulceration. ( Taylor, R, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (89.47) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| WANKA, J | 1 |
| JONES, LI | 1 |
| WOOD, PH | 1 |
| DIXON, AS | 1 |
| VECCHIO, C | 1 |
| FONTANA, A | 1 |
| TAVAZZI, L | 1 |
| Risty, GM | 1 |
| Najarian, MM | 1 |
| Shapiro, SB | 1 |
| Campbel, AN | 1 |
| Beasley, JR | 1 |
| Kenna, AP | 1 |
| Galmiche, JM | 1 |
| Pinsard, M | 1 |
| Thompson, MR | 2 |
| Gray, PH | 1 |
| Pemberton, PJ | 1 |
| Langman, MJ | 1 |
| Henry, D | 1 |
| Donnelly, P | 1 |
| Morris, AF | 1 |
| Hughes, AO | 1 |
| Omogbai, EK | 1 |
| Ozolua, RI | 1 |
| Idaewor, PE | 1 |
| Isah, AO | 1 |
| Taylor, R | 1 |
| Jacyna, MR | 1 |
| Shepherd, AN | 1 |
| Kolbasa, KP | 1 |
| Lancaster, C | 1 |
| Olafsson, AS | 1 |
| Gilbertson, SK | 1 |
| Robert, A | 1 |
| Langridge, CJ | 1 |
| Hodgkinson, R | 1 |
| Woolf, D | 1 |
| Emmanuel, JH | 1 |
| Montgomery, RD | 1 |
| Nicoloff, DM | 1 |
| Puylaert, CB | 1 |
1 review available for indomethacin and Peptic Ulcer Perforation
| Article | Year |
|---|---|
Multiple indomethacin-induced jejunal ulcerations with perforation: a case report with histology.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Indomethacin; Intestinal Mucosa; Jejunal Di | 2007 |
1 trial available for indomethacin and Peptic Ulcer Perforation
| Article | Year |
|---|---|
A five-year clinical trial of indomethacin in osteoarthrosis of the hip.
Topics: Aged; Clinical Trials as Topic; Female; Gastrointestinal Hemorrhage; Hip Joint; Humans; Indomethacin | 1973 |
17 other studies available for indomethacin and Peptic Ulcer Perforation
| Article | Year |
|---|---|
INDOMETHACIN IN RHEUMATIC DISEASES. A CONTROLLED CLINICAL TRIAL.
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Biomedical Research; Drug Hypersensitivity; Gastrointesti | 1964 |
[ON THE GASTRO-LESIONAL EFFECT OF INDOMETHACIN].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Indoles; Indomethacin; Peptic Ulcer Perforation; | 1964 |
Life-threatening illness in those with severe mental handicap.
Topics: Female; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Peptic Ulcer Perforation; | 1981 |
[Pyopneumopericarditis complicating a perforated hiatus hernia ulcer (author's transl)].
Topics: Aged; Female; Hernia, Diaphragmatic; Hernia, Hiatal; Humans; Indomethacin; Peptic Ulcer Perforation; | 1982 |
Indomethacin and perforated duodenal ulcer.
Topics: Aged; Arthritis; Duodenal Ulcer; Female; Humans; Indomethacin; Middle Aged; Peptic Ulcer Perforation | 1980 |
Gastric perforation associated with indomethacin therapy in a pre-term infant.
Topics: Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant, | 1980 |
Indomethacin and perforated duodenal ulcer.
Topics: Duodenal Ulcer; Female; Humans; Indomethacin; Middle Aged; Peptic Ulcer Perforation | 1980 |
Indomethacin and perforated duodenal ulcer.
Topics: Duodenal Ulcer; Humans; Indomethacin; Peptic Ulcer Perforation; Stomach Ulcer | 1980 |
Indomethacin and perforated duodenal ulcer.
Topics: Duodenal Ulcer; Female; Humans; Indomethacin; Middle Aged; Peptic Ulcer Perforation; Stomach Ulcer | 1980 |
Some studies on the rodenticidal action of indomethacin.
Topics: Administration, Oral; Animals; Bile Ducts; Body Weight; Cholestyramine Resin; Diazepam; Drug Interac | 1999 |
Gastro-colic fistula secondary to benign gastric ulceration.
Topics: Aged; Colonic Diseases; Female; Gastric Fistula; Humans; Indomethacin; Intestinal Fistula; Peptic Ul | 1978 |
Perforated ulcer in the elderly.
Topics: Aged; Female; Humans; Indomethacin; Peptic Ulcer Perforation | 1985 |
Indomethacin-induced gastric antral ulcers in hamsters.
Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Cricetinae; Dinoprostone; Disease Models, Animal | 1988 |
A patient with unusual powers of recovery.
Topics: Aged; Duodenal Ulcer; Humans; Indomethacin; Male; Osteoarthritis; Peptic Ulcer Hemorrhage; Peptic Ul | 1987 |
Gastric ulcer and the anti-arthritic drugs.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Indomethacin; Male; Middle Aged; Peptic Ulcer He | 1971 |
Indomethacin. Effect on gastric secretion, parietal cell population, and ulcer provocation in the dog.
Topics: Animals; Dogs; Gastric Juice; Gastric Mucosa; Indomethacin; Peptic Ulcer Hemorrhage; Peptic Ulcer Pe | 1968 |
Barium perforation of a peptic ulcer and barium granuloma of the colon. A report of two rare complications in radiological examination.
Topics: Arthritis, Rheumatoid; Barium; Colon; Duodenum; Esophagus; Granuloma; Humans; Indomethacin; Male; Mi | 1969 |