indomethacin has been researched along with Osteoarthritis of Knee in 8 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " As for adverse events, gastrointestinal complaints were dominant in both treatment groups, but significantly more patients interrupted the treatment in the indomethacin group (22." | 2.74 | [Randomized, double blind, multicentre, parallel group study to compare efficacy and safety of acemetacin and indometacin in patients with activated osteoarthrosis of the knee]. ( Gallacchi, G; Hodinka, L, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bertin, P | 1 |
| Taieb, C | 1 |
| de Boer, TN | 1 |
| Huisman, AM | 1 |
| Polak, AA | 1 |
| Niehoff, AG | 1 |
| van Rinsum, AC | 1 |
| Saris, D | 1 |
| Bijlsma, JW | 1 |
| Lafeber, FJ | 1 |
| Mastbergen, SC | 1 |
| Gallacchi, G | 1 |
| Hodinka, L | 1 |
| Towheed, TE | 1 |
| Leeb, BF | 1 |
| Bucsi, L | 1 |
| Keszthelyi, B | 1 |
| Böhmova, J | 1 |
| Valesova, M | 1 |
| Hawel, R | 1 |
| Mayrhofer, F | 1 |
| Singer, F | 1 |
| Aglas, F | 1 |
| Bröll, H | 1 |
| Pomonis, JD | 1 |
| Boulet, JM | 1 |
| Gottshall, SL | 1 |
| Phillips, S | 1 |
| Sellers, R | 1 |
| Bunton, T | 1 |
| Walker, K | 1 |
| Lequesne, MG | 1 |
| Gencosmanoglu, BE | 1 |
| Eryavuz, M | 1 |
| Dervisoglu, S | 1 |
3 trials available for indomethacin and Osteoarthritis of Knee
| Article | Year |
|---|---|
The chondroprotective effect of selective COX-2 inhibition in osteoarthritis: ex vivo evaluation of human cartilage tissue after in vivo treatment.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; Cartilage, Articular | 2009 |
[Randomized, double blind, multicentre, parallel group study to compare efficacy and safety of acemetacin and indometacin in patients with activated osteoarthrosis of the knee].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Indomethacin; Ma | 2009 |
[Treatment of osteoarthritis of the knee joint. Efficacy and tolerance to acemetacin slow release in comparison to celecoxib].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Confidence Intervals; Data Interpretation | 2004 |
5 other studies available for indomethacin and Osteoarthritis of Knee
| Article | Year |
|---|---|
NSAID-sparing effect of glucosamine hydrochloride in patients with knee osteoarthritis: an analysis of data from a French database.
Topics: Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Databases, Factual; Female; France; Gluco | 2014 |
Published meta-analyses of pharmacological therapies for osteoarthritis.
Topics: Acetaminophen; Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chondroi | 2002 |
Development and pharmacological characterization of a rat model of osteoarthritis pain.
Topics: Alkylating Agents; Analgesics, Opioid; Animals; Celecoxib; Cyclooxygenase Inhibitors; Disease Models | 2005 |
Is there preliminary in-vivo evidences of an influence of nonsteroidal antiinflammatory drug treatment on osteoarthritis progression? Part I.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apazone; Disease Progression; Humans; Indomethacin; Osteoar | 1999 |
Effects of some nonsteroidal anti-inflammatory drugs on articular cartilage of rats in an experimental model of osteoarthritis.
Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Diclofena | 2001 |