indomethacin has been researched along with Osteoarthritis, Hip in 20 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Osteoarthritis, Hip: Noninflammatory degenerative disease of the hip joint which usually appears in late middle or old age. It is characterized by growth or maturational disturbances in the femoral neck and head, as well as acetabular dysplasia. A dominant symptom is pain on weight-bearing or motion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six orthopaedic clinics in Sweden made a comparison of the effects and side effects of Piroxicam (20 mg) and Indomethacin (100 mg) suppositories in 261 patients with painful coxarthrosis on the waiting list for total hip replacement (THR)." | 9.07 | Piroxicam and indomethacin suppositories for painful coxarthrosis. ( Düppe, H; Ersmark, H; Fagerlund, M; Gudmundsson, G; Jacobsson, B; Ordeberg, G; Tjornstrand, B; Wallinder, L, 1992) |
| "The efficacy and side-effect profiles of two formulations of indomethacin were compared in a multi-centre, double-blind, crossover study in 77 patients with osteoarthritis." | 9.06 | A comparison of two formulations of indomethacin ('Flexin Continus' tablets and 'Indocid' capsules) in the treatment of osteoarthritis. ( Abdullah, M; Adebajo, AO; Bacon, P; Bossingham, DH; Daymond, TJ; Grahame, R; Hazleman, BL; Hughes, GR; Luqmani, RA; West, J, 1990) |
| "An open-label, randomised, multicentre study was carried out to compare the efficacy and tolerability of indomethacin capsules and ketoprofen controlled-release capsules in the symptomatic treatment of coxarthrosis." | 5.08 | Efficacy and tolerability of ketoprofen 200 mg controlled-release cps vs indomethacin 50 mg cps in patients with symptomatic hip osteoarthritis. A multicentre study. ( Canesi, B; Dal Prà, A; Ferri, S; Lucchini, M; Marcolongo, R; Oriente, P; Perpignano, G; Serni, U; Tirri, G; Trotta, F, 1997) |
| "Six orthopaedic clinics in Sweden made a comparison of the effects and side effects of Piroxicam (20 mg) and Indomethacin (100 mg) suppositories in 261 patients with painful coxarthrosis on the waiting list for total hip replacement (THR)." | 5.07 | Piroxicam and indomethacin suppositories for painful coxarthrosis. ( Düppe, H; Ersmark, H; Fagerlund, M; Gudmundsson, G; Jacobsson, B; Ordeberg, G; Tjornstrand, B; Wallinder, L, 1992) |
| "The efficacy and side-effect profiles of two formulations of indomethacin were compared in a multi-centre, double-blind, crossover study in 77 patients with osteoarthritis." | 5.06 | A comparison of two formulations of indomethacin ('Flexin Continus' tablets and 'Indocid' capsules) in the treatment of osteoarthritis. ( Abdullah, M; Adebajo, AO; Bacon, P; Bossingham, DH; Daymond, TJ; Grahame, R; Hazleman, BL; Hughes, GR; Luqmani, RA; West, J, 1990) |
| "Among them 23 patients suffered from gonarthrosis and 9 patients from coxarthrosis." | 2.66 | [Double-blind study of the effect of tiaprofenic acid in comparison with indomethacin in patients with degenerative joint diseases]. ( Jajić, I; Jajić, Z, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.00) | 18.7374 |
| 1990's | 12 (60.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pakos, EE | 1 |
| Papadopoulos, DV | 1 |
| Gelalis, ID | 1 |
| Tsantes, AG | 1 |
| Gkiatas, I | 1 |
| Kosmas, D | 1 |
| Tsekeris, PG | 1 |
| Xenakis, TA | 1 |
| Vasileiadis, GI | 1 |
| Sakellariou, VI | 1 |
| Kelekis, A | 1 |
| Galanos, A | 1 |
| Soucacos, PN | 1 |
| Papagelopoulos, PJ | 1 |
| Babis, GC | 1 |
| Kruser, TJ | 1 |
| Kozak, KR | 1 |
| Cannon, DM | 1 |
| Platta, CS | 1 |
| Heiner, JP | 1 |
| Illgen, RL | 1 |
| DIXON, AS | 1 |
| WANKA, J | 1 |
| Ince, A | 1 |
| Sauer, U | 1 |
| Wollmerstedt, N | 1 |
| Hendrich, C | 1 |
| Abraham, C | 1 |
| Hart, J | 1 |
| Locke, SM | 1 |
| Baker, AL | 1 |
| Chayen, J | 1 |
| Bitensky, L | 1 |
| Mehdizadeh, S | 1 |
| Dunham, J | 1 |
| Older, J | 1 |
| Goutallier, D | 1 |
| Colmar, M | 1 |
| Penot, P | 1 |
| Marcolongo, R | 1 |
| Canesi, B | 1 |
| Ferri, S | 1 |
| Oriente, P | 1 |
| Perpignano, G | 1 |
| Serni, U | 1 |
| Tirri, G | 1 |
| Trotta, F | 1 |
| Dal Prà, A | 1 |
| Lucchini, M | 1 |
| Dorn, U | 1 |
| Grethen, C | 1 |
| Effenberger, H | 1 |
| Berka, H | 1 |
| Ramsauer, T | 1 |
| Drekonja, T | 1 |
| Lequesne, MG | 1 |
| Koorevaar, CT | 1 |
| Hu, HP | 1 |
| Lemmens, A | 2 |
| van Kampen, A | 2 |
| Nassif, JM | 1 |
| Ritter, MA | 1 |
| van der Heide, HJ | 1 |
| Koorevaar, RT | 1 |
| Schreurs, BW | 1 |
| Ragnarsson, B | 1 |
| Danckwardt-Lillieström, G | 1 |
| Mjöberg, B | 1 |
| Ersmark, H | 1 |
| Tjornstrand, B | 1 |
| Gudmundsson, G | 1 |
| Düppe, H | 1 |
| Fagerlund, M | 1 |
| Jacobsson, B | 1 |
| Ordeberg, G | 1 |
| Wallinder, L | 1 |
| Vignon, E | 1 |
| Mathieu, P | 1 |
| Louisot, P | 1 |
| Richard, M | 1 |
| Bacon, P | 1 |
| Luqmani, RA | 1 |
| Bossingham, DH | 1 |
| Daymond, TJ | 1 |
| Grahame, R | 1 |
| West, J | 1 |
| Hazleman, BL | 1 |
| Adebajo, AO | 1 |
| Hughes, GR | 1 |
| Abdullah, M | 1 |
| Jajić, I | 1 |
| Jajić, Z | 1 |
| Rashad, S | 1 |
| Revell, P | 1 |
| Hemingway, A | 1 |
| Low, F | 1 |
| Rainsford, K | 1 |
| Walker, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Arthroscopic Surgery Versus Non-surgical Treatment of Osteoarthritis of the Knee[NCT00158431] | Phase 3 | 186 participants (Actual) | Interventional | 1999-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 trials available for indomethacin and Osteoarthritis, Hip
| Article | Year |
|---|---|
Is prophylaxis for heterotopic ossification with radiation therapy after THR associated with early loosening or carcinogenesis?
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Ca | 2020 |
Efficacy and tolerability of ketoprofen 200 mg controlled-release cps vs indomethacin 50 mg cps in patients with symptomatic hip osteoarthritis. A multicentre study.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Drug Administration Schedule; Female | 1997 |
Indomethacin for prevention of heterotopic ossification after hip arthroplasty. A randomized comparison between 4 and 8 days of treatment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Female; Humans; Indomethaci | 1998 |
No effective prophylaxis of heterotopic ossification with short-term ibuprofen.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, | 1999 |
Piroxicam and indomethacin suppositories for painful coxarthrosis.
Topics: Aged; Female; Humans; Indomethacin; Male; Osteoarthritis, Hip; Pain; Piroxicam; Suppositories; Swede | 1992 |
A comparison of two formulations of indomethacin ('Flexin Continus' tablets and 'Indocid' capsules) in the treatment of osteoarthritis.
Topics: Administration, Oral; Capsules; Delayed-Action Preparations; Double-Blind Method; Drug Administratio | 1990 |
[Double-blind study of the effect of tiaprofenic acid in comparison with indomethacin in patients with degenerative joint diseases].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Indometha | 1989 |
Effect of non-steroidal anti-inflammatory drugs on the course of osteoarthritis.
Topics: Aged; Apazone; Bone Regeneration; Clinical Trials as Topic; Drug Evaluation; Femur Head; Hip Joint; | 1989 |
12 other studies available for indomethacin and Osteoarthritis, Hip
| Article | Year |
|---|---|
Prevention of heterotopic ossification in cases of hypertrophic osteoarthritis submitted to total hip arthroplasty. Etidronate or Indomethacin?
Topics: Aged; Arthroplasty, Replacement, Hip; Etidronic Acid; Female; Humans; Indomethacin; Male; Middle Age | 2010 |
Low rates of heterotopic ossification after resurfacing hip arthroplasty with use of prophylactic radiotherapy in select patients.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Arthroplasty, Replacement, H | 2012 |
[INDOMETHACIN, AN ACTIVE MEDICATION FOR COXARTHROSIS].
Topics: Biomedical Research; Drug Therapy; Geriatrics; Hip Joint; Indoles; Indomethacin; Joint Diseases; Ost | 1964 |
No migration of acetabular cups after prophylaxis for heterotopic ossification.
Topics: Acetabulum; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Foreign-Body Migration; Hip Joint | 2007 |
A case of indometacin-induced acute hepatitis developing into chronic autoimmune hepatitis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury, Chro | 2008 |
Testing drugs on human osteoarthritic articular cartilage.
Topics: Aged; Aged, 80 and over; Alcian Blue; Birefringence; Cartilage, Articular; Diclofenac; Female; Hip J | 1994 |
[Periprosthetic ossifications of the hip: role of the duration of postoperative indomethacin therapy in the prevention of ossifications and role of screwed acetabulum in the occurrence of ossification].
Topics: Acetabulum; Bone Screws; Female; Hip Prosthesis; Humans; Indomethacin; Male; Osseointegration; Osteo | 1993 |
Is there preliminary in-vivo evidences of an influence of nonsteroidal antiinflammatory drug treatment on osteoarthritis progression? Part I.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apazone; Disease Progression; Humans; Indomethacin; Osteoar | 1999 |
Indomethacin-induced postoperative psychosis.
Topics: Arthroplasty, Replacement, Hip; Bipolar Disorder; Cyclooxygenase Inhibitors; Humans; Indomethacin; M | 1999 |
Indomethacin for 3 days is not effective as prophylaxis for heterotopic ossification after primary total hip arthroplasty.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, | 1999 |
The triradiate incision for acetabular fractures. A prospective study of 23 cases.
Topics: Acetabulum; Adolescent; Adult; Aged; Combined Modality Therapy; Female; Fractures, Bone; Gait; Hospi | 1992 |
In vitro effect of nonsteroidal antiinflammatory drugs on proteoglycanase and collagenase activity in human osteoarthritic cartilage.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Diclofenac; Endo | 1991 |