indomethacin has been researched along with Orthopedic Disorders in 2 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this post hoc analysis of a prospective, one-arm clinical study of a short-term treatment with acemetacin, a total of 406 patients with pain because of various musculoskeletal diseases with or without joint inflammation was evaluated for the influence of body mass index (BMI) on the reduction of pain at rest, pain at movement and for mobility restriction between visits one and three (primary outcome parameters)." | 9.12 | Lack of influence of body mass index on efficacy and tolerance of acemetacin in short-term treatment of musculoskeletal diseases. ( Dejaco, C; Duftner, C; Schirmer, M, 2007) |
| " In this post hoc analysis of a prospective, one-arm clinical study of a short-term treatment with acemetacin, a total of 406 patients with pain because of various musculoskeletal diseases with or without joint inflammation was evaluated for the influence of body mass index (BMI) on the reduction of pain at rest, pain at movement and for mobility restriction between visits one and three (primary outcome parameters)." | 5.12 | Lack of influence of body mass index on efficacy and tolerance of acemetacin in short-term treatment of musculoskeletal diseases. ( Dejaco, C; Duftner, C; Schirmer, M, 2007) |
| "There was no statistical difference in the mean reduction in pain score between any of the combinations at any point, although combination therapy was the first to reach a clinically significant reduction in pain score (<13 mm), and diclofenac-paracetamol combinations consistently produced a greater reduction in mean pain score than either nonsteroidal antiinflammatory drugs or paracetamol alone." | 5.11 | Randomized double-blind trial comparing oral paracetamol and oral nonsteroidal antiinflammatory drugs for treating pain after musculoskeletal injury. ( Lam, PK; Man, SY; Rainer, TH; Woo, WW, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Woo, WW | 1 |
| Man, SY | 1 |
| Lam, PK | 1 |
| Rainer, TH | 1 |
| Dejaco, C | 1 |
| Duftner, C | 1 |
| Schirmer, M | 1 |
2 trials available for indomethacin and Orthopedic Disorders
| Article | Year |
|---|---|
Randomized double-blind trial comparing oral paracetamol and oral nonsteroidal antiinflammatory drugs for treating pain after musculoskeletal injury.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dizziness; Female; Humans | 2005 |
Lack of influence of body mass index on efficacy and tolerance of acemetacin in short-term treatment of musculoskeletal diseases.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Body Mass Index; Dose-Response Relationship, D | 2007 |