Page last updated: 2024-10-29

indomethacin and Orphan Diseases

indomethacin has been researched along with Orphan Diseases in 5 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Orphan Diseases: Rare diseases that have not been well studied.

Research Excerpts

ExcerptRelevanceReference
" Its characteristics and reported response to indomethacin link it most closely to the trigeminal autonomic cephalalgias (TACs)."4.95LASH: A Review of the Current Literature. ( Halker, R; Kingston, W, 2017)
"Bartter syndrome is an autosomal recessive renal tubulopathy that presents with hypokalemic, hypochloremic metabolic alkalosis associated with increased urinary loss of sodium, potassium, calcium and chloride."1.42A Rare Disorder with Common Clinical Presentation: Neonatal Bartter Syndrome. ( Al-Muhaizae, M; Hussain, S; Tarar, SH, 2015)
"Clinical presentation of Bartter syndrome with hypokalemic periodic paralysis is rare."1.33Case of Bartter syndrome presenting with hypokalemic periodic paralysis. ( Akman, S; Duman, O; Güven, AG; Haspolat, S; Koyun, M, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kingston, W1
Halker, R1
Kawabori, M1
Kurisu, K1
Niiya, Y1
Ohta, Y1
Mabuchi, S1
Houkin, K1
Murayama, T1
Nakamura, K1
Tsuchida, T1
Hussain, S1
Tarar, SH1
Al-Muhaizae, M1
Duman, O1
Koyun, M1
Akman, S1
Güven, AG1
Haspolat, S1

Reviews

1 review available for indomethacin and Orphan Diseases

ArticleYear
LASH: A Review of the Current Literature.
    Current pain and headache reports, 2017, Volume: 21, Issue:8

    Topics: Analgesics; Autonomic Nervous System; Humans; Indomethacin; Paroxysmal Hemicrania; Rare Diseases; Sy

2017

Other Studies

4 other studies available for indomethacin and Orphan Diseases

ArticleYear
Mollaret Meningitis with a High Level of Cytokines in the Cerebrospinal Fluid Successfully Treated by Indomethacin.
    Internal medicine (Tokyo, Japan), 2019, Apr-15, Volume: 58, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cerebrospinal Fluid; Cytokines; Humans; Indomethacin

2019
Eosinophilic pustular folliculitis with extensive distribution: correlation of serum TARC levels and peripheral blood eosinophil numbers.
    International journal of dermatology, 2015, Volume: 54, Issue:9

    Topics: Biomarkers; Chemokine CCL17; Drug Therapy, Combination; Eosinophilia; Eosinophils; Folliculitis; Fol

2015
A Rare Disorder with Common Clinical Presentation: Neonatal Bartter Syndrome.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2015, Volume: 25 Suppl 1

    Topics: Aldosterone; Anti-Inflammatory Agents, Non-Steroidal; Bartter Syndrome; Biomarkers; Humans; Indometh

2015
Case of Bartter syndrome presenting with hypokalemic periodic paralysis.
    Journal of child neurology, 2006, Volume: 21, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Bartter Syndrome; Child; Diagnosis, Differential; Humans; H

2006