indomethacin has been researched along with Nociceptive Pain in 5 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Nociceptive Pain: Dull or sharp aching pain caused by stimulated NOCICEPTORS due to tissue injury, inflammation or diseases. It can be divided into somatic or tissue pain and VISCERAL PAIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Xylene-induced ear edema, carrageenan-induced paw edema and acetic acid-induced vascular permeability test were used to investigate the anti-inflammatory activities of GL in mice." | 3.81 | Observing Anti-inflammatory and Anti-nociceptive Activities of Glycyrrhizin Through Regulating COX-2 and Pro-inflammatory Cytokines Expressions in Mice. ( Li, YX; Ma, L; Niu, Y; Niu, YT; Shi, GJ; Sun, T; Wang, HL; Wu, J; Yu, JQ; Zheng, J, 2015) |
| " The gastrointestinal injury was accompanied by signs of chronic stress: long-lasting increase in corticosterone blood level, adrenal hypertrophy, thymus involution, and loss of body weight." | 3.80 | [Somatic pain sensitivity under indometacin induced gastric and small intestinal injury in rats]. ( Bagaeva, TR; Filaretova, LP; Iarushkina, NI, 2014) |
| "Most drugs used to treat pain and inflammation have potential side effects, which makes it necessary to search for new sources of bioactive molecules." | 1.48 | LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice. ( Alencar Filho, EB; Almeida, JRGDS; Barreiro, EJL; Diniz, TC; Lavor, ÉM; Lima, LM; Lima-Saraiva, SRG; Mendes, RL; Oliveira Júnior, RG; Silva, JC; Silva, MGE; Soares, JMD, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsubota, M | 1 |
| Ozaki, T | 1 |
| Hayashi, Y | 1 |
| Okawa, Y | 1 |
| Fujimura, A | 1 |
| Sekiguchi, F | 1 |
| Nishikawa, H | 1 |
| Kawabata, A | 1 |
| Silva, JC | 1 |
| Oliveira Júnior, RG | 1 |
| Silva, MGE | 1 |
| Lavor, ÉM | 1 |
| Soares, JMD | 1 |
| Lima-Saraiva, SRG | 1 |
| Diniz, TC | 1 |
| Mendes, RL | 1 |
| Alencar Filho, EB | 1 |
| Barreiro, EJL | 1 |
| Lima, LM | 1 |
| Almeida, JRGDS | 1 |
| Iarushkina, NI | 1 |
| Bagaeva, TR | 1 |
| Filaretova, LP | 1 |
| Wang, HL | 1 |
| Li, YX | 1 |
| Niu, YT | 1 |
| Zheng, J | 1 |
| Wu, J | 1 |
| Shi, GJ | 1 |
| Ma, L | 1 |
| Niu, Y | 1 |
| Sun, T | 1 |
| Yu, JQ | 1 |
| Chiriac, AP | 1 |
| Nita, LE | 1 |
| Diaconu, A | 1 |
| Bercea, M | 1 |
| Tudorachi, N | 1 |
| Pamfil, D | 1 |
| Mititelu-Tartau, L | 1 |
5 other studies available for indomethacin and Nociceptive Pain
| Article | Year |
|---|---|
Prostanoid-dependent bladder pain caused by proteinase-activated receptor-2 activation in mice: Involvement of TRPV1 and T-type Ca
Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Cells, Cultured; Cyclooxygenase 2; Dino | 2018 |
LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrage | 2018 |
[Somatic pain sensitivity under indometacin induced gastric and small intestinal injury in rats].
Topics: Adrenal Glands; Animals; Body Weight; Corticosterone; Fasting; Gastric Mucosa; Indomethacin; Intesti | 2014 |
Observing Anti-inflammatory and Anti-nociceptive Activities of Glycyrrhizin Through Regulating COX-2 and Pro-inflammatory Cytokines Expressions in Mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Cyc | 2015 |
Hybrid gels by conjugation of hyaluronic acid with poly(itaconic anhydride-co-3,9-divinyl-2,4,8,10-tetraoxaspiro (5.5)undecane) copolymers.
Topics: Animals; Drug Carriers; Gels; Hyaluronic Acid; Indomethacin; Male; Mice; Nociceptive Pain; Polymers; | 2017 |