indomethacin has been researched along with Neutropenia in 15 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A preterm male infant with a patent ductus arteriosus developed neutropenia during treatment with indomethacin." | 7.73 | Indomethacin-associated neutropenia with subsequent Gram-negative sepsis in a preterm infant. Cause or coincidence? ( Bengtsson, BO; Milstein, JM; Sherman, MP, 2006) |
| " The aims of the present study were to determine, in rats, the role of neutrophils in the pathogenesis of etodolac- and indomethacin-induced gastrointestinal ulceration and blood loss." | 7.69 | Neutropenia does not prevent etodolac- or indomethacin-induced gastrointestinal damage in the rat. ( Fuller, J; Gentry, C; Melarange, R; Smith, PH; Toseland, CD, 1995) |
| "A preterm male infant with a patent ductus arteriosus developed neutropenia during treatment with indomethacin." | 3.73 | Indomethacin-associated neutropenia with subsequent Gram-negative sepsis in a preterm infant. Cause or coincidence? ( Bengtsson, BO; Milstein, JM; Sherman, MP, 2006) |
| " The aims of the present study were to determine, in rats, the role of neutrophils in the pathogenesis of etodolac- and indomethacin-induced gastrointestinal ulceration and blood loss." | 3.69 | Neutropenia does not prevent etodolac- or indomethacin-induced gastrointestinal damage in the rat. ( Fuller, J; Gentry, C; Melarange, R; Smith, PH; Toseland, CD, 1995) |
| "An animal model of leukotriene B4- (LTB4) induced neutropenia has been developed to evaluate LTB4 receptor antagonists in vivo." | 3.68 | LTB4-induced transient neutropenia in the rat: a model for evaluating efficacy and bioavailability of LTB4 receptor antagonists. ( Colombo, C; DiPasquale, G; Fryer, LR; Greenspan, PD; Haston, W; Healy, C; Kotyuk, B; Pastor, G; Pellas, TC; Raychaudhuri, A, 1993) |
| " However, when administered 24 hr before challenge, the same drug dosage had no effect in enhancing survival." | 1.29 | Accelerated hematopoietic recovery and protective effect of the cyclooxygenase inhibitor indomethacin in bacterial infection of neutropenic mice. ( Binaglia, L; Campanile, F; Fioretti, MC; Giampietri, A; Grohmann, U; Puccetti, P, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (46.67) | 18.7374 |
| 1990's | 7 (46.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bengtsson, BO | 1 |
| Milstein, JM | 1 |
| Sherman, MP | 1 |
| Wysocki, H | 1 |
| Björk, J | 1 |
| Smedegård, G | 1 |
| Bagby, GC | 1 |
| Gilbert, DN | 1 |
| Tebbi, CK | 1 |
| Mahmoud, AA | 1 |
| Polmar, S | 1 |
| Gross, S | 1 |
| Costa, RM | 1 |
| Leite, J | 1 |
| Pellas, TC | 1 |
| Colombo, C | 1 |
| Fryer, LR | 1 |
| Pastor, G | 1 |
| Haston, W | 1 |
| Raychaudhuri, A | 1 |
| Kotyuk, B | 1 |
| Greenspan, PD | 1 |
| Healy, C | 1 |
| DiPasquale, G | 1 |
| Campanile, F | 2 |
| Giampietri, A | 1 |
| Grohmann, U | 1 |
| Binaglia, L | 2 |
| Fioretti, MC | 2 |
| Puccetti, P | 2 |
| Melarange, R | 1 |
| Gentry, C | 1 |
| Toseland, CD | 1 |
| Smith, PH | 1 |
| Fuller, J | 1 |
| Grayson, MF | 1 |
| Martin, VM | 1 |
| Markham, RL | 1 |
| Wallace, JL | 1 |
| Keenan, CM | 1 |
| Granger, DN | 1 |
| Wallis, TS | 1 |
| Vaughan, AT | 1 |
| Clarke, GJ | 1 |
| Qi, GM | 1 |
| Worton, KJ | 1 |
| Candy, DC | 1 |
| Osborne, MP | 1 |
| Stephen, J | 1 |
| Smith, JG | 1 |
| Smith, MA | 1 |
| James, I | 1 |
| Blundell, E | 1 |
| Maddison, PJ | 1 |
| Lundberg, C | 1 |
| Gardinali, M | 1 |
| Hugli, TE | 1 |
15 other studies available for indomethacin and Neutropenia
| Article | Year |
|---|---|
Indomethacin-associated neutropenia with subsequent Gram-negative sepsis in a preterm infant. Cause or coincidence?
Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Enterobacter cloacae; Enterobacteriaceae Infection | 2006 |
[Effect of complement 5 activation on neutrophil properties and the pharmacological intervention in various observed phenomena in a hemodialysis model].
Topics: Colchicine; Complement Activation; Complement C5; Dextrans; Humans; Indomethacin; Leukocyte Count; N | 1981 |
Acute microvascular effects of PAF-acether, as studied by intravital microscopy.
Topics: Animals; Cheek; Cricetinae; Extravasation of Diagnostic and Therapeutic Materials; Indomethacin; Inj | 1983 |
Suppression of granulopoiesis by T-lymphocytes in two patients with disseminated mycobacterial infection.
Topics: Adult; Agranulocytosis; Bone Marrow; Cells, Cultured; Female; Hematopoiesis; Humans; Indomethacin; M | 1981 |
The role of eosinophils in granulopoiesis. I. Eosinophilia in neutropenic patients.
Topics: Aged; Agranulocytosis; Bone Marrow; Child; Colony-Forming Units Assay; Eosinophilia; Eosinophils; Fe | 1980 |
[Rapid recovery after treatment with granulocyte-macrophage colony-stimulating factor (GM-CSF) for neutropenia caused by indomethacin].
Topics: Aged; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunologic Factors; Indomethacin; M | 1993 |
LTB4-induced transient neutropenia in the rat: a model for evaluating efficacy and bioavailability of LTB4 receptor antagonists.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non | 1993 |
Accelerated hematopoietic recovery and protective effect of the cyclooxygenase inhibitor indomethacin in bacterial infection of neutropenic mice.
Topics: Animals; Base Sequence; Blood Bactericidal Activity; Colony-Forming Units Assay; Gene Expression; Gr | 1993 |
Neutropenia does not prevent etodolac- or indomethacin-induced gastrointestinal damage in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antilymphocyte Serum; Etodolac; Gastric Mucosa; Ga | 1995 |
Antinative DNA antibodies as a reaction to pyrazole drugs.
Topics: Antibodies; Antibodies, Antinuclear; Antistreptolysin; Binding Sites; Binding Sites, Antibody; Human | 1975 |
Modulation of circulating colony-stimulating activity in mice: combined effects of IL-1 and bacterial or indomethacin treatment.
Topics: Animals; Colony-Stimulating Factors; Female; Hematopoiesis; Indomethacin; Interleukin-1; Mice; Mice, | 1991 |
Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process.
Topics: Animals; Immune Sera; Indomethacin; Leukotriene B4; Male; Methotrexate; Muscle, Smooth; Neutropenia; | 1990 |
The role of leucocytes in the induction of fluid secretion by Salmonella typhimurium.
Topics: Animals; Cell Movement; Cholera Toxin; Ileum; Indomethacin; Leukocyte Count; Leukocytes; Ligation; M | 1990 |
Inhibition of CFU-GM by prostaglandins in a case of chronic T-cell lymphocytosis and neutropenia.
Topics: Agranulocytosis; Cells, Cultured; Chronic Disease; Female; Granulocytes; Hematopoietic Stem Cells; H | 1989 |
Complement activation and membrane lipids in lung vascular injury.
Topics: Animals; Blood Vessels; Complement Activation; Complement C5; Complement C5a; Hemodynamics; Hypotens | 1987 |