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indomethacin and Neuralgia, Sciatic

indomethacin has been researched along with Neuralgia, Sciatic in 12 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"A short-term double-blind sequential trial of indomethacin against placebo in the treatment of low back pain, with and without nerve root pain such as sciatica, showed that indomethacin was significantly more effective than placebo in the group with nerve root pain."9.03Trial of an anti-inflammatory agent (indomethacin) in low back pain with and without radicular involvement. ( Grayson, MF; Jacobs, JH, 1968)
"Treatment with indomethacin was stopped in one case (erythema and conjunctivitis)."6.65Double-blind parallel study of piroxicam versus indomethacin in the treatment of low back pain. ( Osterman, K; Videman, T, 1984)
"A short-term double-blind sequential trial of indomethacin against placebo in the treatment of low back pain, with and without nerve root pain such as sciatica, showed that indomethacin was significantly more effective than placebo in the group with nerve root pain."5.03Trial of an anti-inflammatory agent (indomethacin) in low back pain with and without radicular involvement. ( Grayson, MF; Jacobs, JH, 1968)
"Treatment with indomethacin was stopped in one case (erythema and conjunctivitis)."2.65Double-blind parallel study of piroxicam versus indomethacin in the treatment of low back pain. ( Osterman, K; Videman, T, 1984)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199010 (83.33)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arai, I1
Mao, GP1
Otani, K1
Konno, S1
Kikuchi, S1
Olmarker, K1
Videman, T1
Osterman, K1
Franchi, R1
Grahame, R1
Sotskov, VG1
Jacobs, JH1
Grayson, MF1
Goldie, I1
Trabucchi, L1
Bezza, E1
Mendelek, V1
Jaffé, G1
Rubens-Duval, A1
Villiaumey, J1
Duroux, P1
De Arcangelis, A1

Trials

7 trials available for indomethacin and Neuralgia, Sciatic

ArticleYear
Double-blind parallel study of piroxicam versus indomethacin in the treatment of low back pain.
    Annals of clinical research, 1984, Volume: 16, Issue:3

    Topics: Adult; Aged; Analgesics; Back Pain; Clinical Trials as Topic; Double-Blind Method; Female; Humans; I

1984
[Controlled clinical trial of a new synthetic preparation (parsalmide) in the treatment of inflammatory and degenerative arthro-myopathies].
    Minerva medica, 1976, Oct-31, Volume: 67, Issue:52

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Benzamides; Clinical Trials as Topi

1976
Ketoprofen - clinical efficacy.
    Rheumatology and rehabilitation, 1976, Volume: Suppl

    Topics: Acetaminophen; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Benzophenones; C

1976
Trial of an anti-inflammatory agent (indomethacin) in low back pain with and without radicular involvement.
    British medical journal, 1968, Jul-20, Volume: 3, Issue:5611

    Topics: Back Pain; Clinical Trials as Topic; Gastroenteritis; Headache; Humans; Indomethacin; Placebos; Scia

1968
A clinical trial with indomethacin (indomee(R)) in low back pain and sciatica.
    Acta orthopaedica Scandinavica, 1968, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Aged; Back Pain; Clinical Trials as Topic; Female; Headache; Humans; Indomethacin

1968
A double-blind, between-patient comparison of alclofenac ('Prinalgin') and indomethacin in the treatment of low back pain and sciatica.
    Current medical research and opinion, 1974, Volume: 2, Issue:7

    Topics: Adult; Age Factors; Allyl Compounds; Analgesics; Anti-Inflammatory Agents; Back Pain; Clinical Trial

1974
[Use of indomethacin in the treatment of acute lumbar sciatica].
    Revue du rhumatisme et des maladies osteo-articulaires, 1967, Volume: 34, Issue:4

    Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Indomethacin; Intervertebral Disc Displacemen

1967

Other Studies

5 other studies available for indomethacin and Neuralgia, Sciatic

ArticleYear
Indomethacin blocks the nucleus pulposus-induced effects on nerve root function. An experimental study in dogs with assessment of nerve conduction and blood flow following experimental disc herniation.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2004, Volume: 13, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arteries; Disease Models, Animal; Dogs; Ganglia, S

2004
[Twilight consciousness disorder caused by overdose of indomethacin].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1991, Volume: 91, Issue:5

    Topics: Back Pain; Consciousness Disorders; Humans; Indomethacin; Male; Middle Aged; Psychoses, Substance-In

1991
[Indocid in the treatment of acute lumbago and lumbosciatic algias].
    Minerva ortopedica, 1969, Volume: 20, Issue:9

    Topics: Adult; Aged; Back Pain; Female; Humans; Indomethacin; Male; Middle Aged; Sciatica

1969
[Indomethacin in treatment of lumbago and lumbosciatica].
    Le Journal medical libanais. The Lebanese medical journal, 1972, Volume: 25, Issue:1

    Topics: Adult; Aged; Back Pain; Female; Humans; Indomethacin; Lumbosacral Region; Male; Middle Aged; Sciatic

1972
[On the use in anti-rheumatic therapy of a new non-steroid anti-inflammatory agent: glucosamide of monohydrated (N-p-chloro-benzoyl-2-methyl-5-methoxy)-indol-3-acetic acid].
    La Clinica terapeutica, 1971, Nov-15, Volume: 59, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Brachial Plexus Neuritis; Female; Huma

1971