indomethacin has been researched along with Nerve Degeneration in 5 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| " 2 Delta(9)-and Delta(8)-tetrahydrocannabinol (THC) were toxic when added directly to SH-SY5Y neuroblastoma cells." | 1.32 | Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor. ( Bissonnette, CJ; Klegeris, A; McGeer, PL, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Halim, M | 1 |
| Yee, DJ | 1 |
| Sames, D | 1 |
| Huong, NQ | 1 |
| Nakamura, Y | 1 |
| Kuramoto, N | 1 |
| Yoneyama, M | 1 |
| Nagashima, R | 1 |
| Shiba, T | 1 |
| Yamaguchi, T | 1 |
| Hasebe, S | 1 |
| Ogita, K | 1 |
| Klegeris, A | 1 |
| Bissonnette, CJ | 1 |
| McGeer, PL | 1 |
| Nakano, M | 1 |
| Matsui, H | 1 |
| Miaki, K | 1 |
| Tsuji, H | 1 |
| Neufeld, AH | 1 |
| Chavis, RM | 1 |
| Sears, ML | 1 |
5 other studies available for indomethacin and Nerve Degeneration
| Article | Year |
|---|---|
Imaging induction of cytoprotective enzymes in intact human cells: coumberone, a metabolic reporter for human AKR1C enzymes reveals activation by panaxytriol, an active component of red ginseng.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Animals; Antineoplastic Age | 2008 |
Indomethacin ameliorates trimethyltin-induced neuronal damage in vivo by attenuating oxidative stress in the dentate gyrus of mice.
Topics: Aldehydes; Animals; Caspase 3; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dentat | 2011 |
Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor.
Topics: Astrocytes; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Cell Line; Cytokines; Dronabin | 2003 |
Postlaminectomy adhesion of the cauda equina. Inhibitory effects of anti-inflammatory drugs on cauda equina adhesion in rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachnoiditis; Cauda Equ | 1998 |
Degeneration release of norepinephrine causes transient ocular hyperemia mediated by prostaglandins.
Topics: Animals; Conjunctiva; Fluorescein Angiography; Hyperemia; Indomethacin; Intraocular Pressure; Iris; | 1973 |