Page last updated: 2024-10-29

indomethacin and Nephrosis

indomethacin has been researched along with Nephrosis in 3 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Nephrosis: Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.

Research Excerpts

ExcerptRelevanceReference
"The effects of long-term indomethacin therapy were studied in rats with chronic nephrosis induced by puromycin of aminonucleoside (PAN)."7.66Adverse effect of indomethacin in experimental chronic nephrosis. ( Gros, F; Gubler, MC; Kleinknecht, C; Laouari, D, 1983)
"The effects of long-term indomethacin therapy were studied in rats with chronic nephrosis induced by puromycin of aminonucleoside (PAN)."3.66Adverse effect of indomethacin in experimental chronic nephrosis. ( Gros, F; Gubler, MC; Kleinknecht, C; Laouari, D, 1983)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kleinknecht, C2
Laouari, D1
Gubler, MC2
Gros, F1
Broyer, M1
Palcoux, JB1
Sessa, A1

Trials

1 trial available for indomethacin and Nephrosis

ArticleYear
Irreversible renal failure after indomethacin in steroid-resistant nephrosis.
    The New England journal of medicine, 1980, Mar-20, Volume: 302, Issue:12

    Topics: Child; Chlorambucil; Clinical Trials as Topic; Female; Glomerular Filtration Rate; Humans; Indometha

1980

Other Studies

2 other studies available for indomethacin and Nephrosis

ArticleYear
Adverse effect of indomethacin in experimental chronic nephrosis.
    The International journal of pediatric nephrology, 1983, Volume: 4, Issue:2

    Topics: Animals; Chronic Disease; Female; Indomethacin; Kidney; Nephrosis; Proteinuria; Puromycin Aminonucle

1983
Indomethacin in nephrosis.
    Nephron, 1978, Volume: 20, Issue:3

    Topics: Animals; Basement Membrane; Humans; Indomethacin; Male; Nephrosis; Rats

1978