indomethacin has been researched along with Myocarditis in 16 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Myocarditis: Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indomethacin has been shown to increase virus titers and to worsen cardiac injury in the acute phase of coxsackievirus B4 murine myocarditis." | 7.68 | Focal ventricular thinning caused by indomethacin in the late phase of coxsackievirus B4 murine myocarditis. ( Khatib, G; Khatib, R; Kloner, RA; Reyes, MP; Rezkella, S; Smith, F, 1992) |
| "The authors describe the results of studying the anti-inflammatory effect of indomethacin in 102 young men suffering from acute rheumatic fever (ARF)." | 7.68 | [The results of the indomethacin treatment of patients with acute rheumatic fever]. ( Dzhuzenova, BS; Nasonova, VA, 1991) |
| "Previous studies have shown that indomethacin administered during the early phase of experimental myocarditis may exacerbate the disease process." | 7.67 | Effect of indomethacin in the late phase of coxsackievirus myocarditis in a murine model. ( Khatib, G; Khatib, R; Kloner, R; Rezkalla, S; Smith, F; Sowers, J; Walsh, M, 1988) |
| "Indomethacin has been shown to increase virus titers and to worsen cardiac injury in the acute phase of coxsackievirus B4 murine myocarditis." | 3.68 | Focal ventricular thinning caused by indomethacin in the late phase of coxsackievirus B4 murine myocarditis. ( Khatib, G; Khatib, R; Kloner, RA; Reyes, MP; Rezkella, S; Smith, F, 1992) |
| "The authors describe the results of studying the anti-inflammatory effect of indomethacin in 102 young men suffering from acute rheumatic fever (ARF)." | 3.68 | [The results of the indomethacin treatment of patients with acute rheumatic fever]. ( Dzhuzenova, BS; Nasonova, VA, 1991) |
| "The effect of salicylates or indomethacin usage during viral infection was investigated in a murine model of coxsackievirus B3 myocarditis." | 3.67 | Coxsackievirus B3 murine myocarditis: deleterious effects of nonsteroidal anti-inflammatory agents. ( Khatib, G; Khatib, R; Rezkalla, S, 1986) |
| "Previous studies have shown that indomethacin administered during the early phase of experimental myocarditis may exacerbate the disease process." | 3.67 | Effect of indomethacin in the late phase of coxsackievirus myocarditis in a murine model. ( Khatib, G; Khatib, R; Kloner, R; Rezkalla, S; Smith, F; Sowers, J; Walsh, M, 1988) |
| "The therapeutic action of 5 preparations: specific antikinin substances -- anginin and contrical, and nonspecific -- epsilon-aminocapronic acid, aspirin and indometacine, was tested in 71 rabbits with allergic myocarditis." | 3.65 | [Effect of antikinin agents on the course of experimental myocarditis]. ( Gurevich, MA; Iankovskaia, MO; Odinokova, VA; Paleev, NR; Surovikina, MS, 1976) |
| "Experimental allergic myocarditis was induced in rabbits; a study was made of the effect on the kininogen content and on the activity of kininase in the myocardium, and on its morphological structure produced by anginine, contrical, aspirin, indometacine and epsilon-aminocapronic acid." | 3.65 | [Changes in the kinin system components and structure of the myocardium under the influence of antikinin preparations in allergic myocarditis in rabbits]. ( Gurevich, MA; Iankovskaia, MO; Odinokova, VA; Paleev, NR; Surovikina, MS, 1976) |
| "A 67-year-old man with ulcerative colitis of 1 year's duration was hospitalized with myopericarditis." | 1.28 | [Cardiac involvement in inflammatory bowel disease]. ( Birnbaum, Y; Shpirer, Z, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (62.50) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pergola, G | 1 |
| Cascone, A | 1 |
| Russo, M | 1 |
| Trost, S | 1 |
| Rosé, CD | 1 |
| Bagby, GC | 1 |
| Gilbert, DN | 1 |
| Surovikina, MS | 2 |
| Odinokova, VA | 2 |
| Paleev, NR | 2 |
| Gurevich, MA | 2 |
| Iankovskaia, MO | 2 |
| Khatib, R | 4 |
| Reyes, MP | 2 |
| Khatib, G | 4 |
| Smith, F | 3 |
| Rezkella, S | 1 |
| Kloner, RA | 1 |
| Rezkalla, S | 3 |
| Dzhuzenova, BS | 1 |
| Nasonova, VA | 1 |
| Shakhbazian, IE | 1 |
| Ulybina, OV | 1 |
| Sarsembaeva, RT | 1 |
| Sushkova, NI | 1 |
| Rozvadovskaia, OS | 1 |
| Katargina, LA | 1 |
| Birnbaum, Y | 1 |
| Shpirer, Z | 1 |
| Walsh, M | 1 |
| Sowers, J | 1 |
| Kloner, R | 1 |
| Perez Leiros, C | 1 |
| Sterin-Borda, L | 1 |
| Borda, ES | 1 |
| Bank, I | 1 |
| Marboe, CC | 1 |
| Redberg, RF | 1 |
| Jacobs, J | 1 |
| Calabro, JJ | 1 |
| Katz, RM | 1 |
| Maltz, BA | 1 |
| Novak, V | 1 |
1 review available for indomethacin and Myocarditis
| Article | Year |
|---|---|
A critical reappraisal of juvenile rheumatoid arthritis.
Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine | 1971 |
1 trial available for indomethacin and Myocarditis
| Article | Year |
|---|---|
[Use of chlorbutin in the complex treatment of systemic forms of juvenile rheumatoid arthritis].
Topics: Adolescent; Anti-Inflammatory Agents; Arthritis, Juvenile; Child; Child, Preschool; Chlorambucil; Cl | 1990 |
14 other studies available for indomethacin and Myocarditis
| Article | Year |
|---|---|
Acute pericarditis and myocarditis by Toxoplasma gondii in an immunocompetent young man: a case report.
Topics: Acute Disease; Adult; Aluminum Hydroxide; Antibodies, Protozoan; Carbazoles; Carvedilol; Chest Pain; | 2010 |
Myocarditis and sacroiliitis: 2 previously unrecognized manifestations of tumor necrosis factor receptor associated periodic syndrome.
Topics: Arthritis; Child; Familial Mediterranean Fever; Glucocorticoids; Heterozygote; Humans; Indomethacin; | 2005 |
Suppression of granulopoiesis by T-lymphocytes in two patients with disseminated mycobacterial infection.
Topics: Adult; Agranulocytosis; Bone Marrow; Cells, Cultured; Female; Hematopoiesis; Humans; Indomethacin; M | 1981 |
[Effect of antikinin agents on the course of experimental myocarditis].
Topics: Aminocaproates; Animals; Aprotinin; Aspirin; Drug Evaluation; Drug Therapy, Combination; Indomethaci | 1976 |
[Changes in the kinin system components and structure of the myocardium under the influence of antikinin preparations in allergic myocarditis in rabbits].
Topics: Aminocaproic Acid; Animals; Aprotinin; Aspirin; Heart; Hypersensitivity; Indomethacin; Kininogens; K | 1976 |
Focal ventricular thinning caused by indomethacin in the late phase of coxsackievirus B4 murine myocarditis.
Topics: Animals; Coxsackievirus Infections; Enterovirus B, Human; Heart; Indomethacin; Mice; Myocarditis; My | 1992 |
Enhancement of coxsackievirus B4 virulence by indomethacin.
Topics: Animals; Antibodies, Viral; Coxsackievirus Infections; Disease Models, Animal; Enterovirus B, Human; | 1990 |
[The results of the indomethacin treatment of patients with acute rheumatic fever].
Topics: Acute Disease; Adolescent; Adult; Arthritis; Drug Evaluation; Follow-Up Studies; Humans; Indomethaci | 1991 |
Coxsackievirus B3 murine myocarditis: deleterious effects of nonsteroidal anti-inflammatory agents.
Topics: Animals; Antibodies, Viral; Coxsackievirus Infections; Indomethacin; Interferons; Mice; Myocarditis; | 1986 |
[Cardiac involvement in inflammatory bowel disease].
Topics: Aged; Arrhythmias, Cardiac; Colitis, Ulcerative; Humans; Indomethacin; Male; Myocarditis; Pericardit | 1989 |
Effect of indomethacin in the late phase of coxsackievirus myocarditis in a murine model.
Topics: Animals; Atrial Natriuretic Factor; Chronic Disease; Coxsackievirus Infections; Disease Models, Anim | 1988 |
Lymphocytes infiltration induces dysfunction in autoimmune myocarditis: role of SRS-A.
Topics: Animals; Aspirin; Autoimmune Diseases; B-Lymphocytes; Dithizone; Indomethacin; Male; Mice; Mice, Inb | 1988 |
Myocarditis in adult Still's disease.
Topics: Adult; Arthritis, Juvenile; Biopsy; Drug Therapy, Combination; Endocardium; Humans; Indomethacin; Ma | 1985 |
[Antiphlogistic therapy of carditis in disseminated lupus erythematosus].
Topics: Aged; Anti-Inflammatory Agents; Electrocardiography; Humans; Indomethacin; Lupus Erythematosus, Syst | 1974 |