indomethacin has been researched along with Muscle Spasm in 12 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " 1) H2O2 dissolved in different concentrations produced arterial contractions similar to those by equimolar Oxy-Hb, showing similar dose-response curves." | 5.27 | [On the mechanism underlying spasmogenic actions of oxy-hemoglobin on the cerebral artery, analyzed from the inhibitory effects of nicardipine, procaine and indomethacin]. ( Doi, M, 1988) |
| " In order to examine whether K+ channels play a role in antigen-induced airway responses, the effect of K+ channel blockers on antigen-induced airway smooth muscle contraction and mediator release was examined in vitro in guinea-pigs actively sensitized with ovalbumin (OA)." | 3.69 | Involvement of apamin-sensitive K+ channels in antigen-induced spasm of guinea-pig isolated trachea. ( Ichinose, M; Inoue, H; Ishikawa, J; Maeyama, K; Miura, M; Nakajima, N; Shirato, K; Tomaki, M; Watanabe, T; Yamauchi, H, 1994) |
| " In the carrageenan edema test, eight compounds exhibited higher antiinflammatory activities than did indomethacin." | 3.65 | 6,11-Dihydro-11-oxodibenz [b,e] oxepinacetic acids with potent antiinflammatory activity. ( Kubo, S; Tagawa, H; Tsukada, W; Ueno, K; Yoshioka, T, 1976) |
| "3." | 1.29 | P2-purinoceptors mediating spasm of the isolated uterus of the non-pregnant guinea-pig. ( Hollingsworth, M; Piper, AS, 1996) |
| " 1) H2O2 dissolved in different concentrations produced arterial contractions similar to those by equimolar Oxy-Hb, showing similar dose-response curves." | 1.27 | [On the mechanism underlying spasmogenic actions of oxy-hemoglobin on the cerebral artery, analyzed from the inhibitory effects of nicardipine, procaine and indomethacin]. ( Doi, M, 1988) |
| " The very shallow dose-response curves for flurbiprofen compared with acetylsalicylic acid, especially in the mouse and the rat test systems, are not due to an unreliable or abnormal absorption, which suggests that in these species the mode of action of flurbiprofen is not identical with that of acetylsalicylic acid." | 1.25 | Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent. ( Adams, SS; McCullough, KF; Nicholson, JS, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ueno, K | 1 |
| Kubo, S | 1 |
| Tagawa, H | 1 |
| Yoshioka, T | 1 |
| Tsukada, W | 1 |
| Platt, L | 1 |
| Deboer, SR | 1 |
| Shenderov, K | 1 |
| Probasco, JC | 1 |
| Guterman, EL | 1 |
| Manesh, R | 1 |
| Sperati, CJ | 1 |
| Fuller, CM | 1 |
| Raizner, AE | 1 |
| Chahine, RA | 1 |
| Nahormek, P | 1 |
| Ishimori, T | 1 |
| Verani, M | 1 |
| Nitishin, A | 1 |
| Mokotoff, D | 1 |
| Luchi, RJ | 1 |
| Yamauchi, H | 1 |
| Miura, M | 1 |
| Ichinose, M | 1 |
| Ishikawa, J | 1 |
| Nakajima, N | 1 |
| Tomaki, M | 1 |
| Inoue, H | 1 |
| Maeyama, K | 1 |
| Watanabe, T | 1 |
| Shirato, K | 1 |
| Piper, AS | 1 |
| Hollingsworth, M | 1 |
| Adams, SS | 1 |
| McCullough, KF | 1 |
| Nicholson, JS | 1 |
| Davies, JE | 1 |
| Kellett, DN | 1 |
| Pennington, JC | 1 |
| Niemegeers, CJ | 1 |
| Van Bruggen, JA | 1 |
| Janssen, PA | 1 |
| Doi, M | 1 |
| Piper, PJ | 1 |
| Walker, JL | 1 |
| Roszkowski, AP | 1 |
| Rooks, WH | 1 |
| Tomolonis, AJ | 1 |
| Miller, LM | 1 |
| Thistle, HG | 1 |
12 other studies available for indomethacin and Muscle Spasm
| Article | Year |
|---|---|
6,11-Dihydro-11-oxodibenz [b,e] oxepinacetic acids with potent antiinflammatory activity.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dibenzoxepins; Edema; Female; Le | 1976 |
Egad!
Topics: Aged; Baclofen; Colchicine; Diagnosis, Differential; Female; Gout; Hallux; Hospitalization; Humans; | 2019 |
Exercise-induced coronary arterial spasm: angiographic demonstration, documentation of ischemia by myocardial scintigraphy and results of pharmacologic intervention.
Topics: Angina Pectoris, Variant; Coronary Disease; Exercise Test; Humans; Indomethacin; Male; Middle Aged; | 1980 |
Involvement of apamin-sensitive K+ channels in antigen-induced spasm of guinea-pig isolated trachea.
Topics: Animals; Antigens; Apamin; Charybdotoxin; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro | 1994 |
P2-purinoceptors mediating spasm of the isolated uterus of the non-pregnant guinea-pig.
Topics: Adenosine Triphosphate; Animals; Female; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smoo | 1996 |
Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Cap | 1975 |
The anti-inflammatory and analgesic effects of norvedan a novel, non-steroidal agent.
Topics: Acetates; Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumat | 1976 |
Suprofen, a potent antagonist of acetic acid-induced writhing in rats.
Topics: Acetates; Analgesics; Animals; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Drug Ev | 1975 |
[On the mechanism underlying spasmogenic actions of oxy-hemoglobin on the cerebral artery, analyzed from the inhibitory effects of nicardipine, procaine and indomethacin].
Topics: Animals; Cattle; Cerebral Arterial Diseases; In Vitro Techniques; Indomethacin; Muscle, Smooth, Vasc | 1988 |
The release of spasmogenic substances from human chopped lung tissue and its inhibition.
Topics: Anaphylaxis; Animals; Aorta; Bordetella pertussis; Bronchi; Cromolyn Sodium; Histamine; Humans; Immu | 1973 |
Anti-inflammatory and analgetic properties of d-2-(6'-methoxy-2'-naphthyl)-propionic acid (naproxen).
Topics: Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Fe | 1971 |
Neck and shoulder pain: evaluation and conservative management.
Topics: Aspirin; Braces; Bursitis; Cryosurgery; Diagnosis, Differential; Electromyography; Ethyl Chloride; E | 1969 |