indomethacin has been researched along with Muscle Relaxation in 378 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The tension of isolated rings was measured isometrically to compare the N(G)-nitro-L-arginine- and indomethacin-resistant relaxation by acetylcholine (ACh) in the renal artery from normal rabbits and short term hypercholesterolemia rabbits (0." | 7.71 | Short term hypercholesterolemia alters N(G)-nitro-L-arginine- and indomethacin-resistant endothelium-dependent relaxation by acetylcholine in rabbit renal artery. ( Arai, K; Fujii, H; Honda, H; Kogo, H; Moroe, H; Notoya, Y, 2001) |
| "The aim of this study was to investigate the effect of hypercholesterolemia on the angiotensin II-induced contractions in the isolated aorta and iliac artery of the rabbit, with respect to the role of arachidonate metabolites." | 7.69 | Effects of hypercholesterolemia on the contractions to angiotensin II in the isolated aorta and iliac artery of the rabbit: role of arachidonic acid metabolites. ( Dam, JP; Porsius, AJ; Post, MJ; Riezebos, J; Vleeming, W; Wemer, J, 1997) |
| " (+/-)-alpha-(Benzoylamino)-4-[2-(diethylamino)-ethoxy]-NN-di-propylbenzen-propanamid (tiropramide, CR 605), a new tyrosine derivative with antispastic properties, increases cAMP concentrations within the same dose range that produces smooth muscle relaxation with or without carbachol (0." | 7.66 | Mechanism of smooth muscle relaxation by tiropramide. ( Cifarelli, A; Setnikar, I; Vidal y Plana, RR, 1981) |
| "Treatment with methionine (0." | 5.35 | Chronic methionine load-induced hyperhomocysteinemia impairs the relaxation induced by bradykinin in the isolated rat carotid. ( Bonaventura, D; de Oliveira, AM; Tirapelli, CR, 2009) |
| " Using an in vitro experimental approach, the physiological role of the airway epithelium on smooth muscle relaxation has been investigated by analyzing the dose-response curves for carbachol- or histamine-induced contractions on epithelium intact versus denuded tracheal tissue." | 3.88 | Relaxant effect of ghrelin on guinea pig isolated tracheal smooth muscle: role of epithelial NO and PGE ( Al-Ayed, MSZ, 2018) |
| "The tension of isolated rings was measured isometrically to compare the N(G)-nitro-L-arginine- and indomethacin-resistant relaxation by acetylcholine (ACh) in the renal artery from normal rabbits and short term hypercholesterolemia rabbits (0." | 3.71 | Short term hypercholesterolemia alters N(G)-nitro-L-arginine- and indomethacin-resistant endothelium-dependent relaxation by acetylcholine in rabbit renal artery. ( Arai, K; Fujii, H; Honda, H; Kogo, H; Moroe, H; Notoya, Y, 2001) |
| "The aim of this study was to investigate the effect of hypercholesterolemia on the angiotensin II-induced contractions in the isolated aorta and iliac artery of the rabbit, with respect to the role of arachidonate metabolites." | 3.69 | Effects of hypercholesterolemia on the contractions to angiotensin II in the isolated aorta and iliac artery of the rabbit: role of arachidonic acid metabolites. ( Dam, JP; Porsius, AJ; Post, MJ; Riezebos, J; Vleeming, W; Wemer, J, 1997) |
| " 3 The additional smooth muscle contraction stimulated by 5-HT was increased in the presence of the competitive substrate inhibitor for nitric oxide synthase, NG-nitro-L-arginine methyl ester (L-NAME, 100 microM)." | 3.68 | Endothelium-dependent contractile responses to 5-hydroxytryptamine in the rabbit basilar artery. ( Clark, AH; Garland, CJ; Seager, JM, 1992) |
| " Aspirin, indomethacin, and ONO 3708, a PG receptor antagonist, markedly inhibited the hypoxia-induced contraction, whereas superoxide dismutase and OKY 046, a thromboxane (Tx) A2 synthesis inhibitor, were ineffective." | 3.68 | Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries. ( Matsumoto, T; Toda, N; Yoshida, K, 1992) |
| " This depression was not affected by pretreatment of tissues with propranolol, indomethacin or ouabain, or removal of epithelium, and BA at sufficient concentrations to cause muscle relaxation did not alter intracellular adenosine 3',5'-cyclic monophosphate contents." | 3.68 | Relaxation of canine airway smooth muscle by the heparin preservative benzyl alcohol. ( Chiyotani, A; Horii, S; Kanemura, T; Kobayashi, K; Sakai, N; Takizawa, T; Tamaoki, J, 1990) |
| " (+/-)-alpha-(Benzoylamino)-4-[2-(diethylamino)-ethoxy]-NN-di-propylbenzen-propanamid (tiropramide, CR 605), a new tyrosine derivative with antispastic properties, increases cAMP concentrations within the same dose range that produces smooth muscle relaxation with or without carbachol (0." | 3.66 | Mechanism of smooth muscle relaxation by tiropramide. ( Cifarelli, A; Setnikar, I; Vidal y Plana, RR, 1981) |
| " Contractions of isolated human pial arteries, induced either by exposition to hemorrhagic cerebrospinal fluid (CSF) from patients with subarachnoid hemorrhage and cerebral vasospasm or by exposition to noradrenaline, were markedly augmented after preincubation of the vessel segments with the cyclooxygenase inhibitor indomethacin, while serotonin-induced contractions were unaffected." | 3.66 | Prostaglandin metabolism and prostacyclin in cerebral vasospasm. ( Andersson, KE; Brandt, L; Hindfelt, B; Ljunggren, B; Uski, T, 1983) |
| " Eicosatetraynoic acid (50 microM), nordihydroguairetic acid (50 microM) and QUIN (10 microM) do not exert significant inhibitory effects at the level of smooth muscle relaxation mechanisms as isoproterenol-induced relaxation was resistant to inhibition by these agents." | 3.66 | Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism. ( Peach, MJ; Singer, HA, 1983) |
| " In conclusion, chronic intake of Crataegus prevented aging-related endothelial dysfunction by reducing the prostanoid-mediated contractile responses, most likely by improving the increased oxidative stress and the overexpression of COX-1 and COX-2." | 1.38 | Crataegus special extract WS(®)1442 prevents aging-related endothelial dysfunction. ( Auger, C; Idris-Khodja, N; Koch, E; Schini-Kerth, VB, 2012) |
| "Treatment with methionine (0." | 1.35 | Chronic methionine load-induced hyperhomocysteinemia impairs the relaxation induced by bradykinin in the isolated rat carotid. ( Bonaventura, D; de Oliveira, AM; Tirapelli, CR, 2009) |
| "Nicotine has been shown to reduce both tone and muscular activity in the human colon by releasing nitric oxide (NO) from nerves." | 1.35 | Nicotine-induced neurogenic relaxation in the mouse colon: changes with dextran sodium sulfate-induced colitis. ( Fujino, H; Hamada, Y; Horie, S; Murakami, I; Murayama, T; Yamane, S, 2009) |
| "Capsazepine (10microM) was approximately equally effective to attenuate the contractions evoked by several different inflammatory contractile agonists (LTD(4), PGD(2), histamine), and it relaxed preparations with established tonic contraction due to LTD(4)." | 1.34 | Effects of capsazepine on human small airway responsiveness unravel a novel class of bronchorelaxants. ( Berglund, M; Dalence-Guzmán, MF; Jönsson, P; Persson, CG; Skogvall, S; Sterner, O; Svensson, K, 2007) |
| "Pretreatment with indomethacin abolished the endothelium-dependent attenuation of lemakalim-induced relaxation caused by etomidate." | 1.32 | Inhibitory effects of etomidate and ketamine on adenosine triphosphate-sensitive potassium channel relaxation in canine pulmonary artery. ( Murray, PA; Sohn, JT, 2003) |
| "Pre-treatment with indomethacin, but not with l-NAME, prevented the relaxation induced by alpha-CGRP in pulmonary arteries suggesting that prostaglandins but not nitric oxide (NO) are involved in the intracellular signal transduction pathway." | 1.32 | Effects of alpha calcitonin gene-related peptide in human bronchial smooth muscle and pulmonary artery. ( Amadesi, S; Dinh, QT; Fischer, A; Geppetti, P; Groneberg, DA; Harrison, S; McGregor, GP; Springer, J; Trevisani, M, 2004) |
| " The dosage of 230 mg/kg of nicotinamide given intraperitoneally 15 min before STZ administration (65 mg/kg i." | 1.32 | Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats. ( Kamata, K; Kobayashi, T; Matsumoto, T; Wakabayashi, K, 2004) |
| "The hypertension was induced by oral administration of NO synthase inhibitor N(G)-nitro-L-arginine methylester (L-NAME, 50 mg/kg/day) to normotensive rats for 8 weeks." | 1.31 | Histamine-induced relaxation in pulmonary artery of normotensive and hypertensive rats: relative contribution of prostanoids, nitric oxide and hyperpolarization. ( Török, J, 2000) |
| "Osthole pretreatment (from 1 to 30 microM) enhanced the sodium nitroprusside (0." | 1.31 | Effect of the plant-extract osthole on the relaxation of rabbit corpus cavernosum tissue in vitro. ( Chen, CC; Chen, CF; Chen, J; Chiou, WF, 2000) |
| " In dose-response studies, SLIGRL-NH(2) induced concentration-dependent increases in PGE(2) release (EC(50)=20." | 1.31 | Role of PGE(2) in protease-activated receptor-1, -2 and -4 mediated relaxation in the mouse isolated trachea. ( Henry, PJ; Knight, DA; Lan, RS; Stewart, GA, 2001) |
| " Bronchial rings were incubated with normal or immune serum (100 microl ml(-1) for 2 h) and dose-response curves to TDI (0." | 1.31 | Serum-mediated relaxant response to toluene diisocyanate (TDI) in isolated guinea-pig bronchi. ( Boschetto, P; Chitano, P; De Marzo, N; Fabbri, LM; Faggian, D; Jovine, L; Mapp, CE; Plebani, M, 2001) |
| "Propofol is an excellent anesthetic for patients with hyperreactive airways in which the epithelial layer is damaged." | 1.30 | The relaxant effect of propofol on guinea pig tracheal muscle is independent of airway epithelial function and beta-adrenoceptor activity. ( Hashiba, E; Hashimoto, Y; Hirota, K; Matsuki, A; Sato, T, 1999) |
| "Pretreatment with indomethacin enhanced the relaxation response to acetylcholine in only SHRs at ages 16-20 and 55-60 weeks, thereby cancelling the difference in the relaxation response between WKY rats and SHRs." | 1.30 | Nitric oxide-dependent vasodilator mechanism is not impaired by hypertension but is diminished with aging in the rat aorta. ( Imaoka, Y; Kamada, T; Mio, Y; Okumura, K; Osanai, T; Satoh, K, 1999) |
| "Sepsis was induced by cecal ligation and puncture (CLP)." | 1.29 | Alterations of ex vivo vascular reactivity in intraperitoneal sepsis. ( Chen, SJ; Wu, CC; Yen, MH, 1994) |
| "Chronic hypertension is associated with impaired endothelial function [i." | 1.29 | Effect of cilazapril and indomethacin on endothelial dysfunction in the aortas of spontaneously hypertensive rats. ( Gräser, T; Kauser, K; Rubanyi, GM, 1993) |
| "Clotrimazole (3 microM) was without effect on these responses." | 1.29 | Effects of cytochrome P450 inhibitors on EDHF-mediated relaxation in the rat hepatic artery. ( Davis, SC; Edwards, G; Högestätt, ED; Weston, AH; Zygmunt, PM, 1996) |
| "In indomethacin-treated strips with intact endothelium, L-NOARG attenuated but did not abolish the relaxation." | 1.29 | Mechanism underlying substance P-induced relaxation in dog isolated superficial temporal arteries. ( Enokibori, M; Okamura, T; Toda, N, 1994) |
| "Indomethacin treatment did not affect endothelium-dependent relaxation in the control solution but partially restored the response to ACh in elevated glucose." | 1.29 | Magnesium modulates endothelial dysfunction produced by elevated glucose incubation. ( Duhault, J; Félétou, M; Rasetti, C, 1994) |
| " After VIP dose-response curves were obtained, the strips were preincubated with N omega-nitro-L-arginine (NOARG, an inhibitor of nitric oxide synthase, 10(-4) M." | 1.29 | Modulation of vasoactive intestinal polypeptide (VIP)-mediated relaxation by nitric oxide and prostanoids in the rabbit corpus cavernosum. ( Carson, CC; Davies, MG; Hagen, PO; Kim, JH; Kim, YC, 1995) |
| "Indomethacin was without effect in arteries and veins." | 1.29 | Endothelin receptors mediating functional responses in human small arteries and veins. ( Riezebos, J; Vallance, PJ; Watts, IS, 1994) |
| "Furosemide has recently been shown to be effective in inhibiting various indirect challenges in asthmatic patients, but its mode of action is not yet clear." | 1.29 | Furosemide and bumetanide, but not nedocromil sodium, modulate nonadrenergic relaxation in guinea pig trachea in vitro. ( Demedts, MG; Pype, JL; Verleden, GM, 1994) |
| "Treatment with cimetidine attenuated the sustained relaxation, whereas chlorpheniramine or indomethacin depressed the phasic relaxation." | 1.29 | Histamine actions in dog retinal central arteries as compared to those in middle cerebral and temporal arteries. ( Kani, K; Kitamura, Y; Okamura, T; Toda, N, 1995) |
| "Indomethacin (1 microM) was found to produce approximately a 100% increase in the cholinergic response." | 1.29 | Prejunctional inhibition of cholinergic responses by prostaglandin E2 in human bronchi. ( Conanan, ND; Ellis, JL, 1996) |
| "Treatment with indomethacin inhibited the phasic component in the strips with endothelium, but did not influence the relaxation after endothelium denudation." | 1.28 | [Mechanisms of histamine-induced relaxation in isolated dog mesenteric arteries and veins]. ( Toda, N; Yamazaki, M, 1992) |
| "During oxygen deficiency, control preparations showed a maximal hyperpolarization of delta V = 10." | 1.28 | Role of prostacyclin in normal and arteriosclerotic human coronary arteries during hypoxia. ( Hetzer, R; Müller, J; Rückborn, K; Schnalke, F; Siegel, G, 1992) |
| "Treatment with indomethacin potentiated the contractile response of the arteries and reversed the relaxant response of veins to a contraction." | 1.28 | Comparison of responses to angiotensin II of dog mesenteric arteries and veins. ( Toda, N; Yamazaki, M, 1991) |
| "Treatment with eperisone attenuated the contractions induced by norepinephrine and serotonin in the arteries and those by clonidine and phenylephrine in the veins." | 1.28 | Mechanisms of action of eperisone on isolated dog saphenous arteries and veins. ( Bian, K; Inoue, S; Okamura, T; Okunishi, H; Toda, N, 1989) |
| "Indomethacin pretreatment (14 microM, 30 min) potentiated the relaxation response in intact rings." | 1.27 | Endothelium-dependent relaxation of rabbit aorta. I. Relaxation stimulated by arachidonic acid. ( Peach, MJ; Singer, HA, 1983) |
| "Dipyridamole appears to increase the production of PGI2 even in the presence of PG synthesis inhibition by aspirin or indomethacin." | 1.27 | Modification of angiotensin II-induced relaxation by dipyridamole, phthalazinol and aspirin in isolated dog renal arteries. ( Toda, N; Yamamoto, M, 1983) |
| "Pretreatment with indomethacin (8." | 1.27 | Bronchodilator-mediated relaxation of normal and ovalbumin-sensitized guinea-pig airways: lack of correlation with lung adenylate cyclase activation. ( Burka, JF; Saad, MH, 1984) |
| "Carbachol and SG75 were more effective in inhibiting phasic than tonic tension induced by noradrenaline in GPSMA, but substance P was more effective against tonic tension." | 1.27 | Endothelial-dependent relaxant actions of carbachol and substance P in arterial smooth muscle. ( Bolton, TB; Clapp, LH, 1986) |
| " Des-Arg9-bradykinin-mediated relaxation was inhibited by the specific B1 receptor antagonist [Leu8]des-Arg9-bradykinin which produced parallel shifts in the dose-response curve." | 1.27 | Relaxation of isolated mesenteric arteries by des-Arg9-bradykinin stimulation of B1 receptors. ( Churchill, L; Ward, PE, 1986) |
| "Propranolol was a competitive antagonist of selected TMQ analogues in guinea pig trachea and atria, thus confirming the beta-adrenoceptor actions of these drugs." | 1.27 | Pharmacological evaluation of the beta-adrenoceptor agonist and thromboxane antagonist properties of N-substituted trimetoquinol analogues. ( Adejare, A; Fedyna, JS; Feller, DR; Miller, DD, 1987) |
| " Cyclooxygenase inhibition with indomethacin displaced the dose-response curve to AA to the right but did not prevent the relaxant effects of the fatty acid." | 1.27 | Arachidonic acid-induced endothelial-dependent relaxations of canine coronary arteries: contribution of a cytochrome P-450-dependent pathway. ( Abraham, NG; Mullane, KM; Pinto, A, 1987) |
| " Isolated rings (circular preparations) obtained from rat thoracic aortae responded to increasing concentrations of NE with dose-dependent tonic enhancement, not significantly affected by the presence of indomethacin (10(-6)M); whereas, preincubation with phentolamine (10(-6)M), yohimbine (10(-7)M) or prazosin (10(-8)M), shifted significantly to the right points of the positive inotropic dose-response curve for NE." | 1.27 | Possible prostacyclin involvement on disparate tonic responses to "in vitro" norepinephrine in circular and in longitudinal preparations from rat thoracic aorta. ( Chaud, M; Franchi, AM; Gimeno, AL; Gimeno, MA, 1987) |
| "8 microM) was repeatedly dosed with acetylcholine (ACh, 10 microM)." | 1.27 | The relaxant and spasmogenic effects of some xanthine derivatives acting on guinea-pig isolated trachealis muscle. ( Boyle, JP; Cortijo, J; Curtis-Prior, PB; Davies, JM; Foster, RW; Hofer, P; Small, RC, 1988) |
| " Cimetidine shifted the dose-response curve for histamine to the right, but chlorpheniramine did not alter the response." | 1.27 | Mechanisms of histamine-induced relaxation in isolated monkey and dog coronary arteries. ( Toda, N, 1986) |
| " For higher initial contractions relaxation is slowed during the first minute of wash out, probably because of the sigmoid shape of the dose-response curve." | 1.26 | Relaxation of splenic strips during wash out with amine-free solution after an exposure to noradrenaline. ( Lindmark, E; Schlör, G; Trendelenburg, U, 1976) |
| "5 Indomethacin treatment reversed the isoprenaline desensitization induced by chronic treatment (0." | 1.26 | Tolerance of guinea-pig airway muscle preparations to relaxant agonists induced by chronic exposure to isoprenaline in vivo. ( Brink, C, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 98 (25.93) | 18.7374 |
| 1990's | 202 (53.44) | 18.2507 |
| 2000's | 66 (17.46) | 29.6817 |
| 2010's | 12 (3.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raees, A | 1 |
| Bakhamis, A | 1 |
| Mohamed-Ali, V | 1 |
| Bashah, M | 1 |
| Al-Jaber, M | 1 |
| Abraham, D | 1 |
| Clapp, LH | 2 |
| Orie, NN | 1 |
| Tan, R | 1 |
| Lee, YJ | 1 |
| Cho, KW | 1 |
| Kang, DG | 1 |
| Lee, HS | 1 |
| Al-Ayed, MSZ | 1 |
| Fernandes, VS | 1 |
| Ribeiro, AS | 1 |
| Martínez-Sáenz, A | 1 |
| Blaha, I | 1 |
| Serrano-Margüello, D | 1 |
| Recio, P | 1 |
| Martínez, AC | 1 |
| Bustamante, S | 3 |
| Vázquez-Alba, D | 1 |
| Carballido, J | 1 |
| García-Sacristán, A | 3 |
| Hernández, M | 2 |
| Perusquía, M | 1 |
| Flores-Soto, E | 1 |
| Sommer, B | 1 |
| Campuzano-González, E | 1 |
| Martínez-Villa, I | 1 |
| Martínez-Banderas, AI | 1 |
| Montaño, LM | 1 |
| Rocha, BA | 1 |
| Barroso-Neto, IL | 1 |
| Teixeira, CS | 1 |
| Santiago, MQ | 1 |
| Pires, AF | 1 |
| Souza, LA | 1 |
| Nascimento, KS | 1 |
| Sampaio, AH | 1 |
| Delatorre, P | 1 |
| Assreuy, AM | 2 |
| Cavada, BS | 1 |
| Bonaventura, D | 1 |
| Tirapelli, CR | 1 |
| de Oliveira, AM | 1 |
| Toker, M | 1 |
| Bagcivan, I | 2 |
| Topalkara, A | 1 |
| Karadas, B | 1 |
| Durmus, N | 1 |
| Parlak, A | 1 |
| Kaya, T | 1 |
| Rocha-Sousa, A | 1 |
| Saraiva, J | 1 |
| Amaral, M | 1 |
| Alves-Faria, P | 1 |
| Falcão-Reis, F | 1 |
| Leite-Moreira, AF | 1 |
| Murakami, I | 1 |
| Hamada, Y | 1 |
| Yamane, S | 1 |
| Fujino, H | 1 |
| Horie, S | 1 |
| Murayama, T | 1 |
| Chen, J | 2 |
| Liu, J | 1 |
| Wang, T | 1 |
| Xiao, H | 1 |
| Yin, C | 1 |
| Yang, J | 1 |
| Chen, X | 1 |
| Ye, Z | 1 |
| Occhiuto, F | 1 |
| Pino, A | 1 |
| Palumbo, DR | 1 |
| Samperi, S | 1 |
| De Pasquale, R | 1 |
| Sturlese, E | 1 |
| Circosta, C | 1 |
| Brizic, I | 1 |
| Modun, D | 1 |
| Vukovic, J | 1 |
| Budimir, D | 1 |
| Katalinic, V | 1 |
| Boban, M | 1 |
| Wong, ES | 1 |
| Man, RY | 2 |
| Vanhoutte, PM | 9 |
| Ng, KF | 1 |
| Taylor, SJ | 1 |
| Mann, TS | 1 |
| Henry, PJ | 3 |
| Ana Cecilia, PP | 1 |
| Victor Manuel, PA | 1 |
| Isabel, WF | 1 |
| Enrique, CH | 1 |
| Pedro, LS | 1 |
| Jorge Skiold, LC | 1 |
| Maria del Carmen, CH | 1 |
| Carlos, CH | 1 |
| Idris-Khodja, N | 1 |
| Auger, C | 1 |
| Koch, E | 1 |
| Schini-Kerth, VB | 1 |
| Pulkkinen, V | 1 |
| Manson, ML | 1 |
| Säfholm, J | 1 |
| Adner, M | 1 |
| Dahlén, SE | 1 |
| Tao, L | 1 |
| Hu, HS | 1 |
| Shen, XC | 1 |
| Ang, C | 1 |
| Hillier, C | 1 |
| Johnston, F | 1 |
| Cameron, A | 1 |
| Greer, I | 1 |
| Lumsden, MA | 1 |
| Prasad, K | 2 |
| Gupta, JB | 1 |
| Mukai, Y | 1 |
| Shimokawa, H | 2 |
| Higashi, M | 1 |
| Morikawa, K | 1 |
| Matoba, T | 1 |
| Hiroki, J | 1 |
| Kunihiro, I | 1 |
| Talukder, HM | 1 |
| Takeshita, A | 1 |
| Kelicen, P | 1 |
| Pekiner, C | 1 |
| Sarioğlu, Y | 1 |
| Uma, S | 1 |
| Sohn, JT | 1 |
| Murray, PA | 1 |
| Longhurst, PA | 1 |
| Tarumi, T | 1 |
| Shirahase, H | 1 |
| Kanda, M | 1 |
| Nakamura, S | 1 |
| Kurahashi, K | 1 |
| Rabelo, LA | 1 |
| Cortes, SF | 1 |
| Alvarez-Leite, JI | 1 |
| Lemos, VS | 1 |
| Rodrigues, AJ | 1 |
| Evora, PR | 2 |
| Pearson, PJ | 1 |
| Schaff, HV | 1 |
| Fedan, JS | 5 |
| Dowdy, JA | 1 |
| Johnston, RA | 2 |
| Van Scott, MR | 2 |
| Kommineni, C | 1 |
| Millecchia, LL | 1 |
| Dortch-Carnes, J | 1 |
| Ellis, A | 1 |
| Pannirselvam, M | 1 |
| Anderson, TJ | 1 |
| Triggle, CR | 2 |
| Ajay, M | 1 |
| Gilani, AU | 1 |
| Mustafa, MR | 1 |
| Jun, CH | 1 |
| Lee, TS | 1 |
| Sohn, UD | 1 |
| Jarajapu, YP | 1 |
| Grant, MB | 1 |
| Knot, HJ | 1 |
| Springer, J | 1 |
| Amadesi, S | 1 |
| Trevisani, M | 1 |
| Harrison, S | 1 |
| Dinh, QT | 1 |
| McGregor, GP | 1 |
| Fischer, A | 1 |
| Geppetti, P | 2 |
| Groneberg, DA | 1 |
| Matsumoto, T | 4 |
| Wakabayashi, K | 1 |
| Kobayashi, T | 2 |
| Kamata, K | 3 |
| Usta, C | 1 |
| Sadan, G | 1 |
| Tuncel, B | 1 |
| Higuchi, K | 1 |
| Tominaga, K | 1 |
| Watanabe, T | 1 |
| Uno, H | 1 |
| Shiba, M | 1 |
| Sasaki, E | 1 |
| Tanigawa, T | 1 |
| Takashima, T | 1 |
| Hamaguchi, M | 1 |
| Oshitani, N | 1 |
| Iwanaga, Y | 1 |
| Fukuda, T | 1 |
| Fujiwara, Y | 1 |
| Arakawa, T | 1 |
| Ettarh, RR | 1 |
| Arikawe, AP | 1 |
| Klockgether-Radke, AP | 1 |
| Pawlowski, P | 1 |
| Neumann, P | 1 |
| Hellige, G | 1 |
| Taniguchi, J | 1 |
| Honda, H | 2 |
| Shibusawa, Y | 1 |
| Iwata, T | 1 |
| Notoya, Y | 2 |
| Sekiguchi, F | 2 |
| Hasegawa, N | 1 |
| Inoshita, K | 1 |
| Yonezawa, D | 1 |
| Inoi, N | 1 |
| Kanke, T | 1 |
| Saito, N | 1 |
| Kawabata, A | 1 |
| Sun, X | 1 |
| Ma, S | 1 |
| Zang, YM | 1 |
| Lu, SY | 1 |
| Guo, HT | 1 |
| Bi, H | 1 |
| Wang, YM | 1 |
| Ma, H | 1 |
| Ma, XL | 1 |
| Pei, JM | 1 |
| Vizioli, EO | 1 |
| Spadin, MD | 1 |
| Corrêa, FM | 1 |
| Viaro, F | 1 |
| Chies, AB | 1 |
| Myung, SC | 1 |
| Keum, EM | 1 |
| Park, SY | 1 |
| Lee, MY | 1 |
| Kim, SC | 1 |
| Santos, MR | 1 |
| Nascimento, NM | 1 |
| Antoniolli, AR | 1 |
| Medeiros, IA | 1 |
| Dimo, T | 1 |
| Laurent, F | 1 |
| Rakotonirina, SV | 1 |
| Tan, PV | 1 |
| Kamtchouing, P | 1 |
| Dongo, E | 1 |
| Cros, G | 1 |
| Skogvall, S | 1 |
| Berglund, M | 1 |
| Dalence-Guzmán, MF | 1 |
| Svensson, K | 1 |
| Jönsson, P | 1 |
| Persson, CG | 1 |
| Sterner, O | 1 |
| Ghasemi, M | 2 |
| Sadeghipour, H | 2 |
| Mani, AR | 1 |
| Tavakoli, S | 2 |
| Hajrasouliha, AR | 2 |
| Ebrahimi, F | 2 |
| Dehpour, AR | 4 |
| Hosokawa, M | 1 |
| Gursoy, S | 1 |
| Yildirim, MK | 1 |
| Kaya Temiz, T | 1 |
| Yildirim, S | 1 |
| Yilmaz, A | 1 |
| Turan, M | 1 |
| Soares, PM | 1 |
| Lima, RF | 1 |
| de Freitas Pires, A | 1 |
| Souza, EP | 1 |
| Criddle, DN | 1 |
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| Dong, SP | 1 |
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| Menon, NK | 2 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Retrospective Chart Review Evaluating the Impact of Steroid, Diuretic, and Fluid Use Practice Trends in Extreme Premature Infants at Risk for Bronchopulmonary Dysplasia (BPD) at a Single Center Neonatal Intensive Care Unit[NCT04971694] | 175 participants (Anticipated) | Observational | 2021-09-08 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for indomethacin and Muscle Relaxation
| Article | Year |
|---|---|
Ontogeny of the ductus arteriosus response to prostaglandins and inhibitors of their synthesis.
Topics: Animals; Arachidonic Acids; Ductus Arteriosus; Epoprostenol; Female; Fetus; Gestational Age; Humans; | 1980 |
Possible relationship between the syntheses of endothelium-derived relaxing factor (EDRF) and PAF-acether.
Topics: Animals; Endothelium; In Vitro Techniques; Indomethacin; Muscle Relaxation; Muscle, Smooth, Vascular | 1986 |
376 other studies available for indomethacin and Muscle Relaxation
| Article | Year |
|---|---|
Altered cyclooxygenase-1 and enhanced thromboxane receptor activities underlie attenuated endothelial dilatory capacity of omental arteries in obesity.
Topics: Adipose Tissue; Adult; Apamin; Arteries; Celecoxib; Charybdotoxin; Cyclooxygenase 1; Cyclooxygenase | 2019 |
Beneficial Effect of Berberis amurensis Rupr. on Penile Erection.
Topics: Animals; Area Under Curve; Berberis; Blood Pressure; Cyclic GMP; Epoprostenol; In Vitro Techniques; | 2018 |
Relaxant effect of ghrelin on guinea pig isolated tracheal smooth muscle: role of epithelial NO and PGE
Topics: Animals; Carbachol; Dinoprostone; Ghrelin; Guinea Pigs; Histamine; Indomethacin; Male; Muscle Relaxa | 2018 |
Underlying mechanisms involved in progesterone-induced relaxation to the pig bladder neck.
Topics: Animals; Calcium; Cyclooxygenase Inhibitors; Female; Guanylate Cyclase; In Vitro Techniques; Indomet | 2014 |
Testosterone-induced relaxation involves L-type and store-operated Ca2+ channels blockade, and PGE 2 in guinea pig airway smooth muscle.
Topics: Alprostadil; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cells, | 2015 |
CRLI induces vascular smooth muscle relaxation and suggests a dual mechanism of eNOS activation by legume lectins via muscarinic receptors and shear stress.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Activation; Enzyme Inhibitors; Fabaceae; Hu | 2015 |
Chronic methionine load-induced hyperhomocysteinemia impairs the relaxation induced by bradykinin in the isolated rat carotid.
Topics: Animals; Bradykinin; Cardiovascular Agents; Carotid Arteries; Chronic Disease; Enzyme Inhibitors; Hy | 2009 |
Nifedipine enhances the relaxant effects of cyclo-oxygenase inhibitors on the bovine ciliary muscle.
Topics: Animals; Calcium Channel Blockers; Cattle; Celecoxib; Ciliary Body; Cyclooxygenase Inhibitors; Dose- | 2008 |
ETB2 receptor subtype stimulation relaxes the iris sphincter muscle.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Endothelin-1; Endothelin | 2009 |
Nicotine-induced neurogenic relaxation in the mouse colon: changes with dextran sodium sulfate-induced colitis.
Topics: Animals; Atropine; Bethanechol; Colitis, Ulcerative; Colon; Colon, Descending; Colon, Transverse; De | 2009 |
The relaxation mechanisms of tetrandrine on the rabbit corpus cavernosum tissue in vitro.
Topics: 4-Aminopyridine; Animals; Benzylisoquinolines; Drugs, Chinese Herbal; Enzyme Inhibitors; Glyburide; | 2009 |
Relaxing effects of Valeriana officinalis extracts on isolated human non-pregnant uterine muscle.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Atenolol; Chromatography, High Pressure Liquid; | 2009 |
Differences in vasodilatory response to red wine in rat and guinea pig aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Clotrimazole; Dose-Response Relationship, Drug; Endothelium | 2009 |
Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Anta | 2010 |
Influence of influenza A infection on capsaicin-induced responses in murine airways.
Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhi | 2012 |
Mechanism of the relaxant effect of rosuvastatin lactone on rat aortic rings.
Topics: Animals; Aorta; Hydroxymethylglutaryl CoA Reductases; Imines; In Vitro Techniques; Indomethacin; Lac | 2012 |
Crataegus special extract WS(®)1442 prevents aging-related endothelial dysfunction.
Topics: Aging; Animals; Biological Factors; Biphenyl Compounds; Crataegus; Cyclooxygenase 1; Cyclooxygenase | 2012 |
The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea.
Topics: Albuterol; Animals; Bronchodilator Agents; Carbachol; Charybdotoxin; Chloroquine; Cholinergic Agonis | 2012 |
Endothelium-dependent vasodilatation effects of the essential oil from Fructus alpiniae zerumbet (EOFAZ) on rat thoracic aortic rings in vitro.
Topics: Animals; Aorta, Thoracic; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Endothelium-Dependent | 2013 |
Endothelial function is preserved in pregnant women with well-controlled type 1 diabetes.
Topics: Adult; Analysis of Variance; Arteries; Cyclooxygenase Inhibitors; Diabetes Mellitus, Type 1; Endothe | 2002 |
Relaxant effect of oxygen free radicals on rabbit tracheal smooth muscle.
Topics: Analysis of Variance; Animals; Asthma; Cyclooxygenase Inhibitors; Epithelium; Hydrogen Peroxide; Hyd | 2002 |
Inhibition of renin-angiotensin system ameliorates endothelial dysfunction associated with aging in rats.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Bridged Bicyclo Com | 2002 |
Omeprazole-induced relaxation in rat aorta is partly dependent on endothelium.
Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; In Vitr | 2002 |
Inhibitory effects of etomidate and ketamine on adenosine triphosphate-sensitive potassium channel relaxation in canine pulmonary artery.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; ATP-Binding Cassette Transporters; Cro | 2003 |
Functional development of the rat urinary bladder after pre- or postpubertal castration.
Topics: Adenosine Triphosphate; Animals; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techn | 2003 |
Role of intracellular Ca2+ in endothelium-dependent contraction and relaxation of rabbit intrapulmonary arteries.
Topics: Animals; Aspirin; Calcimycin; Calcium; Endothelium, Vascular; Enzyme Inhibitors; Indomethacin; Ionom | 2003 |
Endothelium dysfunction in LDL receptor knockout mice: a role for H2O2.
Topics: Acetylcholine; Amitrole; Animals; Aorta, Thoracic; Arteriosclerosis; Catalase; Endothelium; Endothel | 2003 |
Endothelium-dependent relaxation to poly-L-arginine in canine coronary arteries.
Topics: Acetylcholine; Animals; Coronary Vessels; Dogs; Endothelium, Vascular; Glyburide; Indomethacin; Musc | 2003 |
Hyperosmolar solution effects in guinea pig airways. I. Mechanical responses to relative changes in osmolarity.
Topics: Animals; Cardiovascular Agents; Guinea Pigs; Indomethacin; Male; Muscle Relaxation; Osmolar Concentr | 2004 |
Hyperosmolar solution effects in guinea pig airways. IV. Lipopolysaccharide-induced alterations in airway reactivity and epithelial bioelectric responses to methacholine and hyperosmolarity.
Topics: Amiloride; Animals; Atropine; Bronchoconstrictor Agents; Diuretics; Drug Interactions; Electrophysio | 2004 |
Catalase has negligible inhibitory effects on endothelium-dependent relaxations in mouse isolated aorta and small mesenteric artery.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Apamin; Cardiovascular Agents; Catalase; Charybdotoxin; Dia | 2003 |
Effects of flavonoids on vascular smooth muscle of the isolated rat thoracic aorta.
Topics: Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Flavonoids; In Vitro Techniq | 2003 |
NO/cyclic GMP pathway mediates the relaxation of feline lower oesophageal sphincter.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cats; Cyclic GMP; Dose-Response R | 2003 |
Myogenic tone and reactivity of the rat ophthalmic artery.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Homeostasis; Indomethacin; Male; Muscl | 2004 |
Effects of alpha calcitonin gene-related peptide in human bronchial smooth muscle and pulmonary artery.
Topics: Acetylcholine; Bronchi; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Endotheli | 2004 |
Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Factors; Chlorides; Diabetes Mellitus, Experimen | 2004 |
The effect of the indomethacin on phosphodiesterase inhibitors mediated responses in isolated trachea preparations.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Guinea Pigs; Histamine; In Vitro Techniques; Indom | 2004 |
Indomethacin, but not Helicobacter pylori, inhibits adaptive relaxation in isolated guinea-pig stomach.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Guinea Pigs; Hel | 2004 |
Effects of diabetes and insulin resistance in pregnant rats on ex vivo vascular reaction to magnesium.
Topics: Alloxan; Animals; Aorta; Blood Glucose; Diabetes Mellitus, Experimental; Female; In Vitro Techniques | 2004 |
Mechanisms involved in the relaxing effect of midazolam on coronary arteries.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Coronary Vessels; Dinoprostone; Dose-Response Rela | 2005 |
Alteration in endothelial function and modulation by treatment with pioglitazone in rabbit renal artery from short-term hypercholesterolemia.
Topics: Acetylcholine; Animals; Biological Factors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhib | 2005 |
Mechanisms for modulation of mouse gastrointestinal motility by proteinase-activated receptor (PAR)-1 and -2 in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Calcium Channel Blockers; Capsaicin; Femal | 2006 |
Vasorelaxing effect of U50,488H in pulmonary artery and underlying mechanism in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic | 2006 |
Acetylcholine-induced aortic relaxation studied in salbutamol treated rats.
Topics: Acetylcholine; Adrenergic beta-Agonists; Albuterol; Animals; Aorta, Thoracic; Cyclic AMP; Dose-Respo | 2005 |
Vasomotor action of insulin on the rabbit normal cavernous smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2006 |
Endothelium-derived factors and k+ channels are involved in the vasorelaxation induced by Sida cordifolia L. in the rat superior mesenteric artery.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Charybdotoxin; Endothelium, Vascular; Enzyme Inhib | 2006 |
Methanol extract of Terminalia superba induces endothelium-independent relaxation of rat thoracic aorta.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Cameroon; Charybdotoxin; Endothel | 2006 |
Effects of capsazepine on human small airway responsiveness unravel a novel class of bronchorelaxants.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Atropine; Bronchi; Bronchodilator Agents; Capsaicin; Cho | 2007 |
Effect of anandamide on nonadrenergic noncholinergic-mediated relaxation of rat corpus cavernosum.
Topics: Animals; Arachidonic Acids; Blotting, Western; Cannabinoid Receptor Modulators; Cannabinoids; Cycloo | 2006 |
Altered arachidonic acid-mediated responses in the perfused kidney of the streptozotocin-induced diabetic rat.
Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Diabetes M | 2006 |
Investigation of relaxant effects of propofol on sheep sphincter of Oddi.
Topics: 4-Aminopyridine; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Drug Combinati | 2007 |
Effects of anethole and structural analogues on the contractility of rat isolated aorta: Involvement of voltage-dependent Ca2+-channels.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Aorta; Calcium; Calcium Channels; Cardiovascular Agents | 2007 |
Role of capsaicin-sensitive afferent neurons in receptive relaxation induced by gastric distension in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bridged Bicyclo Compounds; Calcitonin Gene-Related | 2007 |
The nonadrenergic noncholinergic-mediated relaxation of corpus cavernosum was impaired in chronic lithium-treated rats: improvement with l-arginine.
Topics: Animals; Arginine; Autonomic Nervous System; Cyclooxygenase Inhibitors; Dose-Response Relationship, | 2008 |
O2-sensitivity of beta adrenergic responsiveness in isolated bovine and porcine coronary arteries.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Coronary Vessels; Dose-Response Relationship, | 1984 |
Effects of thyrotropin-releasing hormone (TRH) on the isolated small intestine and taenia coli of the guinea pig.
Topics: Animals; Dose-Response Relationship, Drug; Guanethidine; Guinea Pigs; Hexamethonium Compounds; In Vi | 1980 |
Mechanism of smooth muscle relaxation by tiropramide.
Topics: Animals; Calcium; Colon; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Indometh | 1981 |
Relaxant effects of vasoactive intestinal peptide and bethanechol in cat intrapulmonary artery.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Cats; Drug Interactions; Female; In Vitro Tec | 1983 |
Relaxation and contraction responses to histamine in the human lung parenchymal strip.
Topics: Cimetidine; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Histamine H2 Anta | 1984 |
Pharmacological effects of peptides on tracheal smooth muscle.
Topics: Animals; Carbachol; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle | 1982 |
[Action of adenosine 5'-triphosphate and effects of various purinergic receptor blocking agents on the movements of an isolated guinea pig gallbladder].
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Apamin; Atropine; Female; Gallbladder; | 1983 |
Receptors for substance P. I. The pharmacological preparations.
Topics: Animals; Atropine; Diphenhydramine; Dogs; Female; Guinea Pigs; Heart; Ileum; In Vitro Techniques; In | 1984 |
Effects of 2-nicotinamidoethyl nitrate (SG-75, nicorandil) on indomethacin-induced contractions of isolated dog coronary arteries.
Topics: Animals; Coronary Vessels; Depression, Chemical; Dogs; Epoprostenol; In Vitro Techniques; Indomethac | 1983 |
Prostaglandins and potassium relaxation in vascular smooth muscle of the rat. The role of Na-K ATPase.
Topics: Animals; Arteries; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascul | 1980 |
Cyclic nucleotides and contraction/relaxation in airway muscle: H1 and H2 agonists and antagonists.
Topics: Animals; Cimetidine; Cyclic AMP; Cyclic GMP; Ethylamines; Female; Guinea Pigs; Histamine; Histamine | 1980 |
Tolerance of guinea-pig airway muscle preparations to relaxant agonists induced by chronic exposure to isoprenaline in vivo.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Female; Guinea Pigs; Histamine; In Vitro | 1981 |
Desensitization of beta-adrenoreceptors in guinea-pig trachea: a prostaglandin mediated phenomenon.
Topics: Animals; Drug Resistance; Guinea Pigs; Humans; Indomethacin; Isoproterenol; Male; Muscle Relaxation; | 1982 |
Desensitization of beta-adrenoceptor in guinea pig trachea: a link with the prostaglandin system.
Topics: Animals; Bronchi; Dinoprostone; Guinea Pigs; Humans; Indomethacin; Isoproterenol; Male; Muscle Contr | 1983 |
Mechanism of canine coronary artery relaxation by monensin.
Topics: Aminophylline; Animals; Coronary Vessels; Denervation; Dogs; Dose-Response Relationship, Drug; Femal | 1983 |
Modification of angiotensin II-induced relaxation by dipyridamole, phthalazinol and aspirin in isolated dog renal arteries.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Angiotensin II; Animals; Aspirin; Cyclooxygenase Inhibitors; Di | 1983 |
Decreased lung beta-adrenoceptor function induced by 15-hydroperoxyarachidonic acid.
Topics: Animals; Arachidonic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Leukotriene | 1984 |
Prostaglandin metabolism and prostacyclin in cerebral vasospasm.
Topics: Alprostadil; Epoprostenol; Hemorrhage; Humans; In Vitro Techniques; Indomethacin; Ischemic Attack, T | 1983 |
Relaxation of human isolated pulmonary arteries by prostacyclin (PGI2).
Topics: Adult; Aged; Dinoprost; Dose-Response Relationship, Drug; Electric Stimulation; Epoprostenol; Female | 1983 |
Investigation of the role of prostaglandins in nitroglycerin-induced relaxation of isolated rabbit blood vessels.
Topics: Animals; Arachidonic Acids; Bradykinin; Celiac Artery; In Vitro Techniques; Indomethacin; Male; Mese | 1983 |
Endothelium-dependent relaxation of rabbit aorta. I. Relaxation stimulated by arachidonic acid.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Cate | 1983 |
Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Bacterial Agents; Aorta, Thoracic; Arachidonic Acid; | 1983 |
Endothelial-dependent relaxant effects of vaso-active intestinal polypeptide and arachidonic acid in rat aortic strips.
Topics: Acetylcholine; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Endothelium; Histamine; In Vitro | 1984 |
Bronchodilator-mediated relaxation of normal and ovalbumin-sensitized guinea-pig airways: lack of correlation with lung adenylate cyclase activation.
Topics: Adenylyl Cyclases; Animals; Bronchodilator Agents; Colforsin; Cyclooxygenase Inhibitors; Dinoproston | 1984 |
Tetrodotoxin-resistant relaxation to transmural nerve stimulation in isolated saphenous vein.
Topics: Aminophylline; Animals; Biomechanical Phenomena; Cimetidine; Cyproheptadine; Dogs; Drug Resistance; | 1984 |
Effect of indomethacin on stretch-induced uterine activity in the post-partum.
Topics: Female; Humans; Indomethacin; Labor, Obstetric; Muscle Contraction; Muscle Relaxation; Postpartum Pe | 1983 |
[Effect of a flavinoid (4-methylesculetin) on the response of isolated calf coronary arteries to histamine in the presence of indomethacin].
Topics: Animals; Cattle; Coronary Vessels; Histamine; Indomethacin; Muscle Contraction; Muscle Relaxation; M | 1983 |
[Response of isolated coronary artery segments to serotonin in the presence of a flavinoid, indomethacin and acetylsalicylate].
Topics: Animals; Ascorbic Acid; Aspirin; Cattle; Coronary Vessels; Indomethacin; Muscle Contraction; Muscle | 1983 |
[Effect of a bioflavinoid (4-methylesculetin) on the response of calf hepatic arteries to serotonin in the presence of indomethacin].
Topics: Animals; Cattle; Hepatic Artery; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth | 1983 |
C-6-sulfidopeptide leukotrienes are unlikely to be involved in the endothelium dependent relaxation of rabbit aorta by acetylcholine.
Topics: Acetylcholine; Animals; Aorta; Cyclohexanones; Endothelium; Female; Guinea Pigs; Ileum; In Vitro Tec | 1984 |
Comparison of vasoactive intestinal peptide and isoproterenol relaxant effects in isolated cat airways.
Topics: Animals; Bronchi; Cats; Dose-Response Relationship, Drug; Female; Indomethacin; Isoproterenol; Male; | 1984 |
A proposed role for prostaglandins in the modulation of the relaxation response to urotensin I in isolated rat arteries.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arteries; Aspirin; Atropine; Dose-Response Relationshi | 1981 |
Prostacyclin (PGI2) mediates hypoxic relaxation of bovine coronary arterial strips.
Topics: Animals; Arachidonic Acids; Arteries; Cattle; Coronary Vessels; Epoprostenol; Hypoxia; Indomethacin; | 1981 |
Hypoventilation and elevation of end-expiratory pressure release a substance which relaxes isolated arteries and disaggregates platelets in the presence of cyclooxygenase inhibitors.
Topics: Animals; Aspirin; Biological Assay; Cats; Cattle; Dogs; Epoprostenol; Hypoventilation; Indomethacin; | 1981 |
Investigation of relaxations of the rabbit anococcygeus muscle by nerve stimulation and ATP using the ATP antagonist ANAPP3.
Topics: Adenosine; Adenosine Triphosphate; Animals; Azides; Electric Stimulation; In Vitro Techniques; Indom | 1982 |
Stimulation of cholinergic nerves in dog intestine by adenine nucleotides.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Dogs; Dose-Response Relationship, Drug; Electr | 1980 |
Detrusor dynamics. II. Effect of prostaglandins and their synthesis inhibitor on stress-relaxation time course.
Topics: Animals; Biomechanical Phenomena; Cats; Female; Indomethacin; Male; Muscle Contraction; Muscle Relax | 1981 |
Barium and strontium can substitute for calcium in stimulating nitric oxide production in the endothelium of canine coronary arteries.
Topics: Animals; Arginine; Barium; Calcium; Cations, Divalent; Coronary Vessels; Cyclic GMP; Dogs; Endotheli | 1995 |
K+ channel blockers do not modify relaxation of guinea-pig uterine artery evoked by acetylcholine.
Topics: Acetylcholine; Animals; Arginine; Arteries; Diethylcarbamazine; Drug Interactions; Female; Guinea Pi | 1995 |
Cofactors of constitutive nitric oxide synthase and endothelium-dependent relaxations in canine femoral veins.
Topics: Amino Acid Oxidoreductases; Animals; Biphenyl Compounds; Calmodulin; Dogs; Endothelium; Femoral Vein | 1993 |
Prostacyclin contributes to nitroglycerin-mediated relaxation of human umbilical arteries.
Topics: Epoprostenol; Female; Humans; In Vitro Techniques; Indomethacin; Molsidomine; Muscle Relaxation; Mus | 1993 |
Effect of cilazapril and indomethacin on endothelial dysfunction in the aortas of spontaneously hypertensive rats.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Aorta, Thoracic; Blood Pressure; Cilazapril; Dinopros | 1993 |
A vascular smooth muscles nitric oxide relaxation by a mechanism distinct of calcium changes.
Topics: Acetylcholine; Animals; Arginine; Bradykinin; Calcimycin; Calcium; Coronary Vessels; Cytosol; Dinopr | 1994 |
Role of nitroxidergic nerve in dog retinal arterioles in vivo and arteries in vitro.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arterioles; Atropine; Dogs; Electric Stimulation; End | 1994 |
Mechanism underlying substance P-induced relaxation in dog isolated superficial temporal arteries.
Topics: Analysis of Variance; Animals; Arginine; Cyclic AMP; Cyclic GMP; Dogs; Electrophysiology; Endotheliu | 1994 |
Differential effects of ATP- and 2-methylthioATP-induced relaxation in guinea pig coronary vasculature.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Coronary Vessels; Electrophysiology; Female; G | 1994 |
Magnesium modulates endothelial dysfunction produced by elevated glucose incubation.
Topics: Acetylcholine; Analysis of Variance; Animals; Aorta; Diabetes Mellitus, Experimental; Disease Models | 1994 |
Endothelial modulation of vascular tone in isolated porcine and bovine basilar arteries.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Basilar Artery; Bradykinin; Cattle; Dose-Response Rel | 1994 |
Alterations of ex vivo vascular reactivity in intraperitoneal sepsis.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Body Temperature; Cecum; Disease Models, Animal; D | 1994 |
Involvement of nitroxidergic and noradrenergic nerves in the relaxation of dog and monkey temporal veins.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amino Acid Oxidoreductases; Animals; Argi | 1995 |
Role of thromboxane A2 in bradykinin-induced human isolated small bronchi contraction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Biphenyl Compounds; | 1995 |
The effect of lithium on endothelial-dependent relaxation in rat isolated aorta.
Topics: Animals; Aorta; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Lithium; Male; Muscle Cont | 1995 |
Vasorelaxant effect of the analgesic clonixin on rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Attenuated Ca2+ response to acetylcholine in endothelial cells from aorta of aldosterone-salt hypertensive rats.
Topics: Acetylcholine; Aldosterone; Animals; Arginine; Calcium; Endothelium, Vascular; Fura-2; Hypertension; | 1995 |
Response to anti-human IgE in human pulmonary arteries. Regulation by endothelium.
Topics: Arginine; Chlorpheniramine; Endothelium, Vascular; Epoprostenol; Histamine Release; Humans; Immunoen | 1993 |
Nitric oxide and prostacyclin influence coronary vasomotor tone in perfused rabbit heart and modulate endothelin-1 activity.
Topics: Animals; Arginine; Blood Pressure; Coronary Vessels; Endothelins; Epoprostenol; Heart; In Vitro Tech | 1993 |
Stretch revealed three components in the hyperpolarization of guinea-pig coronary artery in response to acetylcholine.
Topics: Acetylcholine; Animals; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Femal | 1993 |
The endothelium mediates a nitric oxide-independent hyperpolarization and relaxation in the rat hepatic artery.
Topics: Acetylcholine; Animals; Arginine; Benzopyrans; Cell Polarity; Cromakalim; Endothelium, Vascular; Fem | 1994 |
Contractile effects of prostanoids on fetal rabbit ductus arteriosus.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Analysis of Variance; Animals; C | 1995 |
Endothelium-dependent relaxation resistant to NG-nitro-L-arginine in rat aorta.
Topics: Acetylcholine; Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Atropine; Biological Factor | 1995 |
Antagonism by paraquat of the relaxing effects of acetylcholine and A23187 in rat thoracic aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcimycin; Dinoprost; Endothelium, Vascular; Female; Free | 1995 |
Glibenclamide inhibits hypoxic relaxation of isolated porcine coronary arteries under conditions of impaired glycolysis.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; | 1994 |
Endothelium-dependent, nitric oxide-mediated inhibition of angiotensin II-induced contractions in rabbit aorta.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Arginine; Dose-Resp | 1994 |
Mechanism underlying nicotine-induced relaxation in dog saphenous arteries.
Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Dogs; Drug Interactions; Female; Hexamethonium; | 1994 |
Potentiation of nitric oxide-mediated vascular relaxation by SC52608, a superoxide dismutase mimic.
Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Blood Pressure; Chlorides; Cyclic GMP; Endothelium | 1995 |
Relaxation of human isolated mesenteric arteries by vasopressin and desmopressin.
Topics: Adult; Arginine; Arginine Vasopressin; Deamino Arginine Vasopressin; Endothelium, Vascular; Female; | 1994 |
Light-dependent effects of zinc protoporphyrin IX on endothelium-dependent relaxation resistant to N omega-nitro-L-arginine.
Topics: Acetylcholine; Animals; Arginine; Benzopyrans; Biliverdine; Carbon Monoxide; Cromakalim; Darkness; E | 1994 |
Increases in pulse pressure impair acetylcholine-induced vascular relaxation.
Topics: Acetylcholine; Animals; Blood Pressure; Carotid Artery, Common; Endothelium, Vascular; Female; In Vi | 1995 |
Modulation of vasoactive intestinal polypeptide (VIP)-mediated relaxation by nitric oxide and prostanoids in the rabbit corpus cavernosum.
Topics: Animals; Arginine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Indo | 1995 |
Pharmacological reactivity of human epicardial coronary arteries: characterization of relaxation responses to endothelium-derived relaxing factor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Arginine; Coronary | 1994 |
Modulation of relaxant responses evoked by a nitric oxide donor and by nonadrenergic, noncholinergic stimulation by isozyme-selective phosphodiesterase inhibitors in guinea pig trachea.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Atropine; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Ph | 1995 |
The endothelium of the rat renal artery plays an obligatory role in A2 adenosine receptor-mediated relaxation induced by 5'-N-ethylcarboxamidoadenosine and N6-cyclopentyladenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Endothelium, Vascular; Glyburide; I | 1994 |
Basic FGF enhances endothelium-dependent relaxation of the collateral-perfused coronary microcirculation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine Diphosp | 1994 |
Potentiation of nonadrenergic noncholinergic relaxation of human isolated bronchus by selective inhibitors of phosphodiesterase isozymes.
Topics: Atropine; Bronchi; Colforsin; Electric Stimulation; Histamine; Humans; In Vitro Techniques; Indometh | 1994 |
Differential effects of prostanoid synthesis inhibitors on cicletanine-induced relaxation of isolated human epigastric arteries.
Topics: Abdominal Muscles; Antihypertensive Agents; Arteries; Benzopyrans; Cromakalim; Cyclooxygenase Inhibi | 1994 |
Endothelin receptors mediating functional responses in human small arteries and veins.
Topics: Arginine; Arteries; Endothelin Receptor Antagonists; Endothelins; Humans; In Vitro Techniques; Indom | 1994 |
Mechanisms of relaxation by pyrogallol and methylthioninium chloride in perfused rat mesenteric artery.
Topics: Animals; Arginine; Capsaicin; Catalase; Deferoxamine; Dose-Response Relationship, Drug; Indomethacin | 1994 |
Nitric oxide pathway-mediated relaxant effect of bradykinin in the guinea-pig isolated trachea.
Topics: Animals; Arginine; Bradykinin; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Femal | 1994 |
Induction by endothelin-1 of epithelium-dependent relaxation of guinea-pig trachea in vitro: role for nitric oxide.
Topics: Animals; Arginine; Endothelins; Epithelium; Guanylate Cyclase; Guinea Pigs; In Vitro Techniques; Ind | 1993 |
Phorbol myristate acetate inhibits the bradykinin-induced L-nitro-arginine insensitive endothelium-dependent relaxation of bovine coronary artery.
Topics: Animals; Arginine; Bradykinin; Cattle; Coronary Vessels; Dinoprost; Electrophysiology; Endothelium, | 1993 |
Furosemide and bumetanide, but not nedocromil sodium, modulate nonadrenergic relaxation in guinea pig trachea in vitro.
Topics: Animals; Arginine; Atropine; Bumetanide; Chymotrypsin; Drug Therapy, Combination; Electric Stimulati | 1994 |
Gamma-interferon modifies guinea pig airway functions in vitro.
Topics: Animals; Arginine; Carbachol; Cycloheximide; Guinea Pigs; In Vitro Techniques; Indomethacin; Interfe | 1994 |
Vascular effects of loop diuretics: an in vivo and in vitro study in the rat.
Topics: Animals; Blood Pressure; Diuretics; Hemodynamics; In Vitro Techniques; Indomethacin; Male; Muscle Re | 1994 |
Mechanical stimulation of skeletal muscle cells mitigates glucocorticoid-induced decreases in prostaglandin production and prostaglandin synthase activity.
Topics: Animals; Cells, Cultured; Chick Embryo; Dexamethasone; Dinoprost; Dinoprostone; Indomethacin; Kineti | 1994 |
Do perfused small caliber airways of guinea-pig release an epithelium-dependent relaxing factor?
Topics: Animals; Biological Factors; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Epithelium; | 1993 |
Mechanisms of acetylcholine-induced relaxation in dog external and internal ophthalmic arteries.
Topics: Acetylcholine; Animals; Arginine; Atropine; Dogs; Dose-Response Relationship, Drug; Female; Hexameth | 1993 |
Involvement of the "tethered ligand" receptor in thrombin-induced endothelium-mediated relaxations.
Topics: Amino Acid Sequence; Animals; Antithrombins; Arginine; Coronary Vessels; Dogs; Endothelium, Vascular | 1993 |
Endothelium-dependent hyperpolarization caused by bradykinin in human coronary arteries.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Arginine; Benzopyrans; Bradykinin; Calcimycin; Child | 1993 |
Relaxation of vascular smooth muscle induced by low-power laser radiation.
Topics: Animals; Aorta; Arginine; Dose-Response Relationship, Radiation; Indomethacin; Light; Models, Chemic | 1993 |
Effects of pyrimidines on the guinea-pig coronary vasculature.
Topics: Animals; Arginine; Coronary Vessels; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro | 1993 |
Endothelium-derived relaxing factor, hypertension and chronic parathyroidectomy in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Acetylcholine; Animals; Aorta; Arginine; Calcium; Cyclic GMP; Drug Interactions; Extracellular Space | 1993 |
Mechanism of pregnancy-induced attenuation of contraction to phenylephrine in rat aorta.
Topics: Acetylcholine; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Indo | 1993 |
Different responses to acetylcholine in the presence of nitric oxide inhibitor in rat aortae and mesenteric arteries.
Topics: Acetylcholine; Animals; Aorta; Arginine; Barium; Calcium; In Vitro Techniques; Indomethacin; Male; M | 1993 |
Plasma from normal pregnant women alters the reactivity of rabbit aortic smooth muscle with functional endothelium.
Topics: Animals; Aorta; Calcium Chloride; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Indome | 1993 |
Vascular myocyte-derived nitric oxide is an autocrine that limits vasoconstriction.
Topics: Acetylcholine; Animals; Aorta; Arginine; Endothelium, Vascular; In Vitro Techniques; Indomethacin; I | 1993 |
A2-purinoceptor-mediated relaxation in the guinea-pig coronary vasculature: a role for nitric oxide.
Topics: Adenosine; Animals; Antihypertensive Agents; Arginine; Coronary Vessels; Female; Guinea Pigs; In Vit | 1993 |
Non-adrenergic, non-cholinergic neural activation in guinea-pig bronchi: powerful and frequency-dependent stabilizing effect on tone.
Topics: Animals; Autonomic Nervous System; Bronchi; Electric Stimulation; Female; Guinea Pigs; Histamine; In | 1993 |
Relaxant effects of nucleotides in guinea pig isolated, perfused trachea: lack of involvement of prostanoids, Cl- channels and adenosine.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo | 1993 |
Acetylcholine-induced relaxation in bovine isolated mesenteric arteries is suppressed by polymorphonuclear leukocytes.
Topics: Acetylcholine; Animals; Arginine; Catalase; Cattle; Endothelium, Vascular; Free Radical Scavengers; | 1993 |
Bronchodilatation of guinea-pig perfused bronchioles induced by the H3-receptor for histamine: role of epithelium.
Topics: Acetylcholine; Animals; Anticonvulsants; Arginine; Bronchi; Bronchodilator Agents; Epithelium; Femal | 1993 |
Vasomotor responses of canine coronary arterial rings to NG-monomethyl-L-arginine and N omega nitro L-arginine methyl ester.
Topics: Animals; Aorta, Abdominal; Arginine; Biotransformation; Coronary Vessels; Cycloheximide; Dogs; Drug | 1993 |
Mechanisms of histamine-induced relaxation in external and internal ophthalmic arteries.
Topics: Animals; Carotid Artery, External; Carotid Artery, Internal; Dinoprostone; Dogs; Endothelium, Vascul | 1993 |
In vitro and ex vivo inhibitory effects of L- and D-enantiomers of NG-nitro-arginine on endothelium-dependent relaxation of rat aorta.
Topics: Acetylcholine; Animals; Aorta; Arginine; Calcimycin; Endothelium, Vascular; In Vitro Techniques; Ind | 1993 |
Partial mediation by nitric oxide of the relaxation of human isolated detrusor strips in response to electrical field stimulation.
Topics: Arginine; Electric Stimulation; Humans; In Vitro Techniques; Indomethacin; Methylene Blue; Muscle Co | 1993 |
Hypoxic relaxation in functionally intact cattle coronary artery segments involves K+ ATP channels.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arteries; Calcium; Calcium Channel Blockers; Cattle; Cor | 1995 |
Histamine actions in dog retinal central arteries as compared to those in middle cerebral and temporal arteries.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Arteries; Chlorpheniramine; Cimetidine; D | 1995 |
Evidence that epithelium-derived relaxing factor released by bradykinin in the guinea pig trachea is nitric oxide.
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Bradykinin; Culture Techniques; Cyclic GMP; Cyclooxy | 1996 |
High-dose tumor necrosis factor alpha produces an impairment of hamster diaphragm contractility. Attenuation with a prostaglandin inhibitor.
Topics: Animals; Cricetinae; Cyclooxygenase Inhibitors; Diaphragm; Dinoprostone; Indomethacin; Isometric Con | 1996 |
Prejunctional inhibition of cholinergic responses by prostaglandin E2 in human bronchi.
Topics: Acetylcholine; Adult; Atropine; Barium Compounds; Bronchi; Charybdotoxin; Chlorides; Cyclooxygenase | 1996 |
Effect of pregnancy on mechanisms of relaxation in human omental microvessels.
Topics: Acetylcholine; Adult; Arginine; Arterioles; Bradykinin; Drug Interactions; Enzyme Inhibitors; Female | 1996 |
Effects of Androctonus crassicauda scorpion venom on endothelium-dependent and -independent vascular responses of rabbit aorta.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Endothelium, Vascu | 1996 |
Role of potassium channels in endothelium-dependent relaxation resistant to nitroarginine in the rat hepatic artery.
Topics: Acetylcholine; Animals; Arginine; Biological Factors; Chloride Channels; Endothelium, Vascular; Enzy | 1996 |
Nitric oxide (EDRF) enhances the vasorelaxing effect of dihydropyridine calcium antagonists in isolated human middle cerebral arteries.
Topics: Adult; Arginine; Calcium Channel Blockers; Cerebral Arteries; Cyclooxygenase Inhibitors; Dihydropyri | 1996 |
Study of the mechanisms involved in adenosine-5'-O-(2-thiodiphosphate) induced relaxation of rat thoracic aorta and pancreatic vascular bed.
Topics: Adenosine Diphosphate; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Indomethacin; Mal | 1996 |
Excitatory response of rabbit myometrium to nitric oxide in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta; Arginine; Cyclic GMP; Electric Stimulation; | 1996 |
Effect of the K+ channel openers NIP-121 and cromakalim on melittin-induced relaxation of guinea-pig isolated trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzopyrans; Cromakalim | 1996 |
Dual regulation of cerebrovascular tone by UTP: P2U receptor-mediated contraction and endothelium-dependent relaxation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; Cattle; Cerebr | 1996 |
Effects of cytochrome P450 inhibitors on EDHF-mediated relaxation in the rat hepatic artery.
Topics: Acetylcholine; Animals; Benzopyrans; Biological Factors; Clotrimazole; Cromakalim; Dose-Response Rel | 1996 |
ATP and beta,gamma-methylene ATP produce relaxation of guinea-pig isolated trachealis muscle via actions at P1 purinoceptors.
Topics: Adenosine Triphosphate; Animals; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; | 1996 |
Effects of potassium-channel opener HOE 234 in guinea-pig airways.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchi; Bronchodilator Agents; Chromans; Cyclooxygena | 1996 |
Carbon monoxide-induced relaxation of the ductus arteriosus in the lamb: evidence against the prime role of guanylyl cyclase.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Cyclic GMP; Cyto | 1996 |
Characterisation of bradykinin receptors from juvenile pig coronary artery.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Coron | 1996 |
Recombinant human erythropoietin enhances vasoconstrictor tone via endothelin-1 and constrictor prostanoids.
Topics: Acetylcholine; Animals; Aorta; Carotid Arteries; Cells, Cultured; Dose-Response Relationship, Drug; | 1996 |
Effects of vasopressin on human renal arteries.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Endothelium, | 1996 |
Mechanism of cooling-induced relaxation in the isolated guinea-pig trachea.
Topics: Animals; Cold Temperature; Guinea Pigs; Hot Temperature; In Vitro Techniques; Indomethacin; Male; Ma | 1996 |
Mechanism of hydroxyl radical-induced modulation of vascular tone.
Topics: Animals; Aorta; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hydroxyl Radical; Indomethacin; | 1997 |
Mechanism of adrenomedullin-induced relaxation in isolated canine retinal arteries.
Topics: Adrenomedullin; Animals; Calcitonin Gene-Related Peptide; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inh | 1997 |
Impairment of endothelium-dependent relaxation of the isolated basilar artery from streptozotocin-induced diabetic rats.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Basilar Artery; Diabetes Mellitus, Experimental | 1996 |
Endothelial prostanoids involved in the relaxation produced by acetylcholine in the human pulmonary artery.
Topics: Acetylcholine; Adult; Aged; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Middle | 1996 |
Protein kinase inhibition and the oestrogen-like relaxant effects of genistein on isolated rat aorta.
Topics: Animals; Aorta; Brain; Calcium; Dinoprost; Enzyme Inhibitors; Estradiol; Estrogens, Non-Steroidal; G | 1997 |
Arachidonic acid products-mediated contraction induced by bradykinin in relaxed mesenteric arterial rings from Holtzman rats.
Topics: Animals; Arachidonic Acid; Bradykinin; Bradykinin Receptor Antagonists; Dinoprost; Endothelium, Vasc | 1997 |
Association of gestational diabetes with abnormal maternal vascular endothelial function.
Topics: Acetylcholine; Arginine; Diabetes, Gestational; Endothelium, Vascular; Enzyme Inhibitors; Female; Hu | 1997 |
Studies on endothelium-dependent vasorelaxation by hydralazine in porcine coronary artery.
Topics: Animals; Coronary Vessels; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Dactinomycin; Endothel | 1997 |
Furosemide-induced bronchodilation in the rat bronchus: evidence of a role for prostaglandins.
Topics: Animals; Bronchi; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Diuretics; | 1997 |
P1-purinoceptor-mediated vasodilatation and vasoconstriction in hypoxia.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Hypoxia; In Vitro Techniques; In | 1996 |
Flavonoid-induced gastroprotection in rats: role of blood flow and leukocyte adherence.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Disease Models, Animal; Flavonoids; | 1997 |
Involvement of voltage-dependent potassium channels in the EDHF-mediated relaxation of rat hepatic artery.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Anti-Arrhythmia Agents; Apamin; Binding, Competitive; Biolo | 1997 |
Depolarizing cardiac arrest and endothelium-derived hyperpolarizing factor-mediated hyperpolarization and relaxation in coronary arteries: the effect and mechanism.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Biological Factors; Cor | 1997 |
Relaxant effects of vasoactive intestinal peptide on pulmonary artery in chronically hypoxic rats.
Topics: Animals; Cyclooxygenase Inhibitors; Guanylate Cyclase; Hypoxia; Indomethacin; Male; Masoprocol; Meth | 1996 |
Characterization of endothelium-derived relaxing factors released by bradykinin in human resistance arteries.
Topics: Arteries; Biological Factors; Bradykinin; Cyclooxygenase Inhibitors; Endothelium; Endothelium, Vascu | 1997 |
Apamin-sensitive K+ channels involved in the inhibition of acetylcholine-induced contractions in lamb coronary small arteries.
Topics: Acetylcholine; Animals; Apamin; Arginine; Calcimycin; Calcium; Coronary Vessels; Cyclooxygenase Inhi | 1997 |
Role of the endothelium in the relaxation induced by propofol and thiopental in isolated arteries from man.
Topics: Aged; Analysis of Variance; Anesthetics, Intravenous; Cyclooxygenase Inhibitors; Endothelium, Vascul | 1997 |
The comparison of the responsiveness of human isolated internal mammary and gastroepiploic arteries to levcromakalim: an alternative approach to the management of graft spasm.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arteries; Benzopyrans; Coronary | 1997 |
Chronic inhibition of NO synthase enhances the production of prostacyclin in coronary arteries through upregulation of the cyclooxygenase type 1 isoform.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bradykinin; Coronary Vessels; Cyclooxygenase 1; Dogs; Enzyme | 1997 |
Effects of hypercholesterolemia on the contractions to angiotensin II in the isolated aorta and iliac artery of the rabbit: role of arachidonic acid metabolites.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Arachidonic Acid | 1997 |
Evidence for a role for nitric oxide in relation of the frog oesophageal body to electrical field stimulation.
Topics: Adrenergic Agents; Animals; Arginine; Carbachol; Cyclooxygenase Inhibitors; Electric Stimulation; En | 1997 |
Interaction between prostaglandins and selective phosphodiesterase inhibitors in isolated guinea-pig trachea in vitro.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Drug Interactions; Female; Guanidines; | 1997 |
Macrophage-induced nitric oxide and prostanoid dependent relaxation of arterial smooth muscles.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arteries; Aspirin; Cells, Cultured; Dogs | 1997 |
Neuronal stimulant actions of prostacyclin and its novel mimetics.
Topics: Acetates; Animals; Colon; Epoprostenol; Gastrointestinal Motility; Guinea Pigs; Humans; Indomethacin | 1997 |
Gender differences in endothelium-dependent relaxations do not involve NO in porcine coronary arteries.
Topics: Adrenergic alpha-Agonists; Animals; Bradykinin; Brimonidine Tartrate; Calcimycin; Cholesterol; Coron | 1997 |
N(G)-nitro-L-arginine- and indomethacin-resistant endothelium-dependent relaxation in the rabbit renal artery: effect of hypercholesterolemia.
Topics: Animals; Aorta, Thoracic; Cholesterol, Dietary; Dose-Response Relationship, Drug; Endothelium, Vascu | 1997 |
Inhibitory actions of endothelial products on mechanical and calcium responses in aortic smooth muscle cells.
Topics: Animals; Aorta; Biological Factors; Bradykinin; Calcium; Cattle; Cells, Cultured; Cyclic GMP; Cycloo | 1997 |
Endothelial dysfunction exacerbates the impairment of relaxation by lysophosphatidylcholine in porcine coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Inflammatory Agent | 1997 |
Decreased endothelium-dependent vasoconstriction to noradrenaline in acute-stressed rats is potentiated by previous chronic stress: nitric oxide involvement.
Topics: Acute Disease; Animals; Aorta; Chronic Disease; Cyclooxygenase Inhibitors; Endothelium, Vascular; En | 1998 |
P2U-receptor mediated endothelium-dependent but nitric oxide-independent vascular relaxation.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Endothelium, Vascular; Female; Indomethac | 1998 |
Involvement of bradykinin B1 and B2 receptors in relaxation of mouse isolated trachea.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Dinoprostone; Enzyme Inhibitors; Female; Guany | 1998 |
Regulation of ductus arteriosus patency by nitric oxide in fetal lambs: the role of gestation, oxygen tension, and vasa vasorum.
Topics: Aminoquinolines; Animals; Aorta; Calcimycin; Ductus Arteriosus; Ductus Arteriosus, Patent; Enzyme In | 1998 |
Effects of methylene blue and indomethacin on sodium nitroprusside-induced relaxations of the guinea pig tracheal smooth muscle.
Topics: Animals; Carbachol; Cyclooxygenase Inhibitors; Guanylate Cyclase; Guinea Pigs; Indomethacin; Male; M | 1998 |
Biphasic relaxant response of ovine trachealis muscle to electrical field stimulation: influence of cooling.
Topics: Analysis of Variance; Animals; Atropine; Capsaicin; Carbachol; Cold Temperature; Electric Stimulatio | 1999 |
Effect of interleukin-1beta on the ascending and descending reflex in rat small intestine.
Topics: Animals; Cyclooxygenase Inhibitors; Electric Stimulation; Histamine Antagonists; Imidazoles; In Vitr | 1998 |
Prostaglandin and nitric oxide interactions in rat aorta.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Interactions; Fem | 1998 |
Endothelium-dependent relaxation induced by hawthorn extract in rat mesenteric artery.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Endothelium, Vascular; Enzyme Inhibitors; In Vitro | 1998 |
Effects of initial length on intrinsic tone in guinea pig tracheal smooth muscle.
Topics: Animals; Biomechanical Phenomena; Cyclooxygenase Inhibitors; Guinea Pigs; Indomethacin; Isometric Co | 1998 |
Analysis of an H1 receptor-mediated, zinc-potentiated vasoconstrictor action of the histidyl dipeptide carnosine in rabbit saphenous vein.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carnosine; Cimetidine; Drug Interactions; Histamin | 1998 |
Mechanism for substance P-induced relaxation of precontracted airway smooth muscle during development.
Topics: Aging; Animals; Animals, Newborn; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; Enzyme In | 1999 |
Endothelial P2Y receptors induce hyperpolarisation of vascular smooth muscle by release of endothelium-derived hyperpolarising factor.
Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Factors; Dose-Resp | 1999 |
The cyclo-oxygenase-dependent regulation of rabbit vein contraction: evidence for a prostaglandin E2-mediated relaxation.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; Arachidonic Acid; Bi | 1999 |
Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice.
Topics: Acetylcholine; Animals; Aorta; Blood Vessels; Carotid Arteries; Coronary Vessels; Cromakalim; Dose-R | 1999 |
Enhanced, unaltered and impaired nitric oxide-mediated endothelium-dependent relaxation in experimental diabetes mellitus: importance of disease duration.
Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibi | 1999 |
V2-receptor-mediated relaxation of human renal arteries in response to desmopressin.
Topics: Adult; Aged; Antidiuretic Hormone Receptor Antagonists; Cyclooxygenase Inhibitors; Deamino Arginine | 1999 |
Endothelium-derived relaxing, contracting and hyperpolarizing factors of mesenteric arteries of hypertensive and normotensive rats.
Topics: Acetylcholine; Animals; Apamin; Blood Pressure; Body Weight; Bridged Bicyclo Compounds, Heterocyclic | 1999 |
[The role of guanylate cyclase and arachidonic acid metabolites in the regulation of epithelium-dependent relaxation in the smooth muscle from the rat trachea].
Topics: Adrenergic alpha-Agonists; Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Epithelium; Guanyla | 1999 |
NANC relaxation of the circular smooth muscle of the oesophagus of the Agama lizard involves the L-arginine-nitric oxide synthase pathway.
Topics: Adrenergic Agents; Animals; Arginine; Electric Stimulation; Epithelium; Esophagus; Female; Guanethid | 1999 |
A2B adenosine receptors mediate relaxation of the pig intravesical ureter: adenosine modulation of non adrenergic non cholinergic excitatory neurotransmission.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relatio | 1999 |
Nitric oxide-dependent vasodilator mechanism is not impaired by hypertension but is diminished with aging in the rat aorta.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Biological Factors; Blood Pressure; Body Weight; Eic | 1999 |
The relaxant effect of propofol on guinea pig tracheal muscle is independent of airway epithelial function and beta-adrenoceptor activity.
Topics: Anesthetics, Intravenous; Animals; Carbachol; Epithelium; Female; Guinea Pigs; Histamine; In Vitro T | 1999 |
Preferential impairment of nitric oxide-mediated endothelium-dependent relaxation in human cervical arteries after irradiation.
Topics: Acetylcholine; Adult; Aged; Arteries; Calcimycin; Combined Modality Therapy; Cyclooxygenase Inhibito | 1999 |
Increased activity of H2O2 in aorta isolated from chronically streptozotocin-diabetic rats: effects of antioxidant enzymes and enzymes inhibitors.
Topics: Amitrole; Animals; Antioxidants; Aorta; Catalase; Cyclooxygenase Inhibitors; Diabetes Mellitus, Expe | 1999 |
Low dose of lipopolysaccharide induces a delayed enhanced nitric oxide-mediated relaxation in rat aorta.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Dose-Response Rela | 1999 |
Pharmacological characterization of metamizol-induced relaxation in phenylephrine-precontracted rabbit thoracic aorta smooth muscle.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Dipyrone; Dose-Response Relations | 1999 |
Cyclic AMP mediates EDHF-type relaxations of rabbit jugular vein.
Topics: Acetylcholine; Animals; Biological Factors; Colforsin; Cyclic AMP; Endothelium, Vascular; Gap Juncti | 1999 |
Glycyrrhetinic acid-sensitive mechanism does not make a major contribution to non-prostanoid, non-nitric oxide mediated endothelium-dependent relaxation of rat mesenteric artery in response to acetylcholine.
Topics: Acetylcholine; Animals; Arachidonic Acid; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Gl | 1999 |
Hydrogen peroxide decreases Ca(2+) sensitivity in airway smooth muscle by inhibiting rMLC phosphorylation.
Topics: Acetylcholine; Animals; Calcium; Dogs; Hydrogen Peroxide; In Vitro Techniques; Indomethacin; Muscle | 1999 |
The endothelial component of cannabinoid-induced relaxation in rabbit mesenteric artery depends on gap junctional communication.
Topics: Acetylcholine; Animals; Arachidonic Acids; Benzofurans; Cannabinoid Receptor Modulators; Cannabinoid | 1999 |
Characterization of nitric oxide- and prostaglandin-independent relaxation in response to acetylcholine in rabbit renal artery.
Topics: Acetylcholine; Animals; Biological Factors; Cytochrome P-450 Enzyme Inhibitors; Endothelium, Vascula | 1999 |
Relaxant action produced by sodium nitroprusside in guinea-pig tracheal muscle.
Topics: Animals; Atropine; Calcium; Cyclic GMP; Dinoprostone; Female; Fura-2; Guinea Pigs; Indoles; Indometh | 1999 |
Effects of K(+) channel inhibitors on relaxation induced by flufenamic and tolfenamic acids in guinea-pig trachea.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Calcium Channels, L-Type | 1999 |
Chronic exposure to hypoxia attenuates contractile responses in rat airways in vitro: a possible role for nitric oxide.
Topics: Albuterol; Animals; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Cyclooxygenase Inhibi | 1999 |
Pranidipine enhances relaxation produced by endothelium-derived relaxing factor in carotid artery.
Topics: Acetylcholine; Animals; Calcium Channel Blockers; Carotid Arteries; Dihydropyridines; Dose-Response | 1999 |
Modulation of airway smooth muscle tone by protease activated receptor-1,-2,-3 and -4 in trachea isolated from influenza A virus-infected mice.
Topics: Animals; Carbachol; Cyclooxygenase Inhibitors; Epithelial Cells; Indomethacin; Influenza A virus; Is | 2000 |
Nitric oxide and prostaglandin interactions in the relaxant responses of rat aorta: influence of pregnancy.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Factors; Cyclooxygenase Inhibitors; Enzyme Inhib | 1999 |
Alterations in relaxation to lactate and H(2)O(2) in human placental vessels from gestational diabetic pregnancies.
Topics: Adolescent; Adult; Arachidonic Acid; Colforsin; Diabetes, Gestational; Female; Humans; Hydrogen Pero | 2000 |
Pregnancy does not alter the response of uterine arteries to vasoactive intestinal polypeptide.
Topics: Acetylcholine; Animals; Arteries; Cyclooxygenase Inhibitors; Diethylcarbamazine; Enzyme Inhibitors; | 2000 |
Effect of the plant-extract osthole on the relaxation of rabbit corpus cavernosum tissue in vitro.
Topics: Animals; Coumarins; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techni | 2000 |
Histamine-induced relaxation in pulmonary artery of normotensive and hypertensive rats: relative contribution of prostanoids, nitric oxide and hyperpolarization.
Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Histamine; Hypertension; Indom | 2000 |
EDHF, NO and a prostanoid: hyperpolarization-dependent and -independent relaxation in guinea-pig arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Biological Fa | 2000 |
The effect of cyclic GMP on rabbit corporal smooth muscle tone and its modulation by cyclo-oxygenase products.
Topics: Acetylcholine; Aminoquinolines; Animals; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Indometha | 2000 |
Hyperosmolarity-induced relaxation and prostaglandin release in guinea pig trachea in vitro.
Topics: Animals; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; In Vitro Te | 2000 |
Xanthorrhizol induces endothelium-independent relaxation of rat thoracic aorta.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug | 2000 |
Lyprinol: anti-inflammatory and uterine-relaxant activities in rats, with special reference to a model for dysmenorrhoea.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Bivalvia; Cyclooxygenase | 2000 |
Effect of protease-activated receptor (PAR)-1, -2 and -4-activating peptides, thrombin and trypsin in rat isolated airways.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bronchi; Bronchodilator Agents; Cyclooxygenase Inhibitors; Dos | 2000 |
Role of PGE(2) in protease-activated receptor-1, -2 and -4 mediated relaxation in the mouse isolated trachea.
Topics: Animals; Caenorhabditis elegans Proteins; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhib | 2001 |
Vascular endothelial growth factor-mediated endothelium-dependent relaxation is blunted in spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Endothelial Growth | 2001 |
Endothelial factors involved in the bradykinin-induced relaxation of the guinea-pig aorta.
Topics: Animals; Aorta, Thoracic; Bradykinin; Carbenoxolone; Endothelium, Vascular; Gap Junctions; Guinea Pi | 2000 |
Short term hypercholesterolemia alters N(G)-nitro-L-arginine- and indomethacin-resistant endothelium-dependent relaxation by acetylcholine in rabbit renal artery.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Hypercholesterolemia; Indomethacin; Muscle Relaxation | 2001 |
Serum-mediated relaxant response to toluene diisocyanate (TDI) in isolated guinea-pig bronchi.
Topics: Albumins; Analysis of Variance; Animals; Blood Proteins; Bronchi; Capsaicin; Culture Techniques; Dos | 2001 |
Effect of progesterone on the contractile response of isolated pulmonary artery in rabbits.
Topics: Animals; Calcium; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Muscle | 2001 |
Impaired relaxation to acetylcholine in 2K-1C hypertensive rat aortas involves changes in membrane hyperpolarization instead of an abnormal contribution of endothelial factors.
Topics: Acetylcholine; Animals; Aorta; Biological Factors; Cyclic GMP; Disease Models, Animal; Endothelium, | 2000 |
Relaxation induced by histamine is not endothelium dependent in tail arteries of L-NAME-treated rats.
Topics: Animals; Arteries; Blood Pressure; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibito | 2000 |
Gastrin-releasing peptides from Xenopus laevis: purification, characterization, and myotropic activity.
Topics: Amino Acid Sequence; Animals; Bombesin; Dose-Response Relationship, Drug; Gastrin-Releasing Peptide; | 2001 |
Characterization of adenosine action in isolated rat renal artery. Possible role of adenosine A(2A) receptors.
Topics: Adenosine; Animals; Caffeine; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Indomethacin; Iso | 2000 |
Time-dependent reduction of acetylcholine-induced relaxation in aortic rings of cholestatic rats.
Topics: Acetylcholine; Animals; Aorta; Arginine; Cholestasis; Cyclooxygenase Inhibitors; Endothelium, Vascul | 2001 |
Relaxation of guinea pig trachealis during electrical field stimulation increases with age.
Topics: Aging; Animals; Bronchoconstriction; Cyclooxygenase Inhibitors; Electric Stimulation; Guinea Pigs; I | 2002 |
Impaired endothelium-mediated relaxation in isolated cerebral arteries from insulin-resistant rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Calcimycin; Endothelium, Vascular; Enz | 2002 |
Pharmacological differences of non-adrenergic inhibitory response and of ATP-induced relaxation in guineq-pig tracheal strip-chains.
Topics: Adenosine Triphosphate; Animals; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Muscle Relaxat | 1976 |
Atypical (relaxant) response to histamine in cat bronchus.
Topics: Airway Resistance; Animals; Bronchi; Burimamide; Carbachol; Cats; Female; Histamine; Histamine H1 An | 1977 |
Effects of urotensin I on the isolated rat tail artery: possible mediation of the relaxation responses by cAMP.
Topics: Animals; Arteries; Cyclic AMP; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle R | 1978 |
The direct influence of thyrotropin-releasing hormone (TRH) on the smooth muscle of rat duodenum.
Topics: Animals; Bucladesine; Duodenum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle | 1979 |
PGE2 is a more potent vasodilator of the lamb ductus arteriosus than is either PGI2 or 6 keto PGF1alpha.
Topics: Animals; Ductus Arteriosus; Epoprostenol; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscl | 1978 |
Pharmacological evaluation of the lung strip of neonatal swine.
Topics: Animals; Animals, Newborn; Carbachol; Female; Histamine; Indomethacin; Isoproterenol; Lung; Male; Mu | 1979 |
Prostaglandin mediated relaxation of coronary artery strips under hypoxia.
Topics: Acetylcholine; Animals; Aspirin; Cattle; Coronary Vessels; In Vitro Techniques; Indomethacin; Muscle | 1978 |
Relaxation of splenic strips during wash out with amine-free solution after an exposure to noradrenaline.
Topics: Animals; Biological Transport; Catechol O-Methyltransferase Inhibitors; Cats; Cocaine; Corticosteron | 1976 |
Activation of an epithelial neurokinin NK-1 receptor induces relaxation of rat trachea through release of prostaglandin E2.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Binding Sites; Biological Factors; Dinoprost; Dinoprostone; E | 1992 |
Effect of nitro-L-arginine on endothelium-dependent hyperpolarizations and relaxations of pig coronary arteries.
Topics: Animals; Arginine; Bradykinin; Coronary Vessels; Dinoprost; Dose-Response Relationship, Drug; Endoth | 1992 |
Kinin-induced relaxations of the rat duodenum.
Topics: Animals; Apamin; Bradykinin; Duodenum; Female; In Vitro Techniques; Indomethacin; Male; Muscle Relax | 1992 |
Endothelium-derived nitric oxide and cyclooxygenase products modulate corpus cavernosum smooth muscle tone.
Topics: Acetylcholine; Animals; Bradykinin; Cholic Acids; Cyclic GMP; Eicosanoids; Endothelium, Vascular; Gu | 1992 |
Mechanisms of action of cicletanine in human and guinea pig resistance arteries.
Topics: Animals; Antihypertensive Agents; Arteries; Charybdotoxin; Diuretics; Drug Interactions; Eicosanoids | 1992 |
Endothelium-dependent relaxation and noradrenaline sensitivity in mesenteric resistance arteries of streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Female; In | 1992 |
Endothelium-dependent modulation of resistance vessel contraction: studies with NG-nitro-L-arginine methyl ester and NG-nitro-L-arginine.
Topics: Acetylcholine; Animals; Arginine; Endothelium, Vascular; Female; Indomethacin; Mesenteric Arteries; | 1992 |
Diabetes mellitus impairs neurogenic and endothelium-dependent relaxation of rabbit corpus cavernosum smooth muscle.
Topics: Acetylcholine; Animals; Diabetes Mellitus, Experimental; Electric Stimulation; Endothelium, Vascular | 1992 |
Pharmacological properties of acetylcholine mediated relaxation of the human umbilical artery.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Female; Humans; In Vitro Techniques; Indomethacin | 1992 |
Endothelium-dependent relaxation to alpha-methyl-5-hydroxytryptamine in isolated horse coronary arteries.
Topics: Animals; Coronary Vessels; Endothelium, Vascular; Horses; In Vitro Techniques; Indomethacin; Muscle | 1992 |
Histamine receptors on human isolated pulmonary arterial muscle preparations: effects of endothelial cell removal and nitric oxide inhibitors.
Topics: Arginine; Burimamide; Chlorpheniramine; Cimetidine; Dimaprit; Endothelium, Vascular; Histamine; Huma | 1992 |
Endothelium-dependent contractile responses to 5-hydroxytryptamine in the rabbit basilar artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arginine; Basilar Artery; Endothelium, Vascular; Fe | 1992 |
Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries.
Topics: Animals; Aspirin; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; Female; Humans; Hypoxia; | 1992 |
Converting-enzyme inhibitors potentiate bradykinin-induced relaxation in vitro.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Ve | 1992 |
Evidence that nitric oxide does not mediate the hyperpolarization and relaxation to acetylcholine in the rat small mesenteric artery.
Topics: Acetylcholine; Animals; Arginine; Biological Factors; Electrophysiology; Endothelium, Vascular; In V | 1992 |
[Mechanisms of histamine-induced relaxation in isolated dog mesenteric arteries and veins].
Topics: Animals; Chlorpheniramine; Cimetidine; Dogs; Dose-Response Relationship, Drug; Epoprostenol; Female; | 1992 |
Inhibition of endothelium-dependent vasorelaxation by arginine analogues: a pharmacological analysis of agonist and tissue dependence.
Topics: Acetylcholine; Alkylation; Animals; Aorta, Thoracic; Arginine; Glyburide; In Vitro Techniques; Indom | 1992 |
Role of prostacyclin in normal and arteriosclerotic human coronary arteries during hypoxia.
Topics: Arteriosclerosis; Coronary Vessels; Epoprostenol; Humans; Hypoxia; In Vitro Techniques; Indomethacin | 1992 |
Calcitonin gene-related peptide (CGRP)-induced cyclic AMP, cyclic GMP and vasorelaxant responses in rat thoracic aorta are antagonized by blockers of endothelium-derived relaxant factor (EDRF).
Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcitonin Gene-Related Peptide; Cyclic AMP; Cyclic GMP; En | 1991 |
Conversion of angiotensin I to angiotensin II in dog isolated renal artery: role of two different angiotensin II-generating enzymes.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; A | 1990 |
Cytochrome P450-dependent arachidonic acid metabolites, 19- and 20-hydroxyeicosatetraenoic acids, enhance sodium-potassium ATPase activity in vascular smooth muscle.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Cytochrome P-450 Enzyme System; Hydroxyeicosatetraen | 1990 |
Pharmacological characterization of the vascular muscarinic receptors mediating relaxation and contraction in rabbit aorta.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Antihy | 1991 |
Heterogeneous involvement of endothelium in calcitonin gene-related peptide-induced relaxation in coronary arteries from rat.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Endothelium, V | 1991 |
Calcitonin gene-related peptide (CGRP) causes endothelium-dependent cyclic AMP, cyclic GMP and vasorelaxant responses in rat abdominal aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Abdominal; Calcitonin Gene-Related Peptide; Cyclic AMP; | 1991 |
Comparison of responses to angiotensin II of dog mesenteric arteries and veins.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Arachidonic Acid; Calcimycin; Dogs; Endotheli | 1991 |
Endothelium-independent relaxation of rabbit coronary artery by 17 beta-oestradiol in vitro.
Topics: Animals; Aorta, Thoracic; Arginine; Calcium Channel Blockers; Coronary Vessels; Endothelium, Vascula | 1991 |
NIP-121 and cromakalim, potassium channel openers, preferentially suppress prostanoid-induced contraction of the guinea-pig isolated trachea.
Topics: Animals; Arachidonic Acid; Benzopyrans; Cromakalim; Dinoprost; Glyburide; Guinea Pigs; Indomethacin; | 1991 |
Non-adrenergic, non-cholinergic regulation of guinea-pig airway smooth muscle-indomethacin-induced changes and segmental differences.
Topics: Animals; Autonomic Nervous System; Bronchi; Electric Stimulation; Female; Guinea Pigs; Humans; In Vi | 1991 |
15-lipoxygenase metabolites of arachidonic acid evoke contractions and relaxations in isolated canine arteries: role of thromboxane receptors, endothelial cells and cyclooxygenase.
Topics: Animals; Arachidonate 15-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Arteries; Coronary Vesse | 1991 |
Endothelium-dependent relaxant effect of thrombocytin, a serine proteinase from Bothrops atrox snake venom, on isolated pig coronary arteries.
Topics: Animals; Arginine; Batroxobin; Coronary Vessels; Crotalid Venoms; Dinoprost; Endothelium, Vascular; | 1991 |
The role of the epithelium in modulating the responses of guinea-pig trachea induced by bradykinin in vitro.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Albuterol; Animals; Bradyk | 1990 |
Vascular smooth muscle relaxation by endothelium-dependent beta 1-adrenergic action.
Topics: Animals; Aorta; Cyclic GMP; Endothelium, Vascular; Indomethacin; Male; Methylene Blue; Metoprolol; M | 1990 |
Endothelium-dependent effects of pentoxifylline in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Colforsin; Endothelium, Vascular; In Vitro Techniques; Indo | 1991 |
Hypercholesterolemia impairs endothelium-dependent relaxation of rabbit corpus cavernosum smooth muscle.
Topics: Acetylcholine; Animals; Cholesterol, Dietary; Dose-Response Relationship, Drug; Endothelium; Hyperch | 1991 |
Mechanisms of action of endothelin 1 in maturing rabbit airway smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Aging; Animals; Dinoprostone; Eicosano | 1991 |
Epithelium-derived inhibitory factor in human bronchus.
Topics: Animals; Asthma; Biological Factors; Bronchi; Carbachol; Histamine; Humans; In Vitro Techniques; Ind | 1990 |
Converting enzyme inhibition in isolated porcine resistance artery potentiates bradykinin relaxation.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bridged Bicyclo Compo | 1990 |
Non-adrenergic, non-cholinergic contractions in the electrically field stimulated guinea-pig trachea.
Topics: Animals; Atropine; Autonomic Nervous System; Bronchi; Capsaicin; Electric Stimulation; Guinea Pigs; | 1990 |
Vasodilatory effects of lidocaine on epicardial porcine coronary arteries.
Topics: Animals; Coronary Vessels; Female; In Vitro Techniques; Indomethacin; Lidocaine; Male; Muscle Relaxa | 1990 |
Pertussis toxin inhibits endothelium-dependent relaxations evoked by fluoride.
Topics: Acetylcholine; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Coronary Vessels | 1990 |
Endothelium-dependent effects of cigarette smoke components on tone of porcine intrapulmonary arteries in vitro.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Endothelium, Vascular; Hexamethonium Compounds; In Vitr | 1990 |
The leukotriene D4/E4 antagonist SR2640: recent results with smooth muscle preparations.
Topics: Animals; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Indomethacin; Leukotriene E4; Muscle Re | 1990 |
Relaxation of canine airway smooth muscle by the heparin preservative benzyl alcohol.
Topics: Acetylcholine; Animals; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Bronchi; Cyclic AMP; Dogs | 1990 |
Evidence for generation of a large amount of nitric oxide-like vascular smooth muscle relaxant by cholesterol-rich neutrophils.
Topics: Animals; Aorta; Arginine; Calcium; Cholesterol; Humans; In Vitro Techniques; Indomethacin; Kinetics; | 1990 |
A model to study physiological activation of phospholipase A2 and vasorelaxation by lysophosphatidylcholine.
Topics: Acetylcholine; Animals; Bradykinin; Calcimycin; Carbon Radioisotopes; Cattle; Endothelium; Enzyme Ac | 1990 |
Pharmacological evidence for the existence of a local renin-angiotensin system in porcine interlobar renal arteries.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Dinoprost; Enalapril; In Vitro Techniques; | 1990 |
Relaxations of guinea-pig isolated trachea induced by platelet-activating factor are epithelial-dependent and are antagonised by WEB 2086.
Topics: Albuterol; Animals; Azepines; Epithelium; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Musc | 1990 |
Indomethacin improves the impaired endothelium-dependent relaxations in small mesenteric arteries of the spontaneously hypertensive rat.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Hypertension; Indomethacin; Isometric Contraction; Ma | 1990 |
Evidence that A2 purinoceptors are involved in endothelium-dependent relaxation of the rat thoracic aorta.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals | 1990 |
5-Carboxamidotryptamine: a potent agonist mediating relaxation and elevation of cyclic AMP in the isolated neonatal porcine vena cava.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Atropine; Cimetidine; Cocaine; Cyclic AMP; D | 1986 |
Endothelial-dependent relaxant actions of carbachol and substance P in arterial smooth muscle.
Topics: Animals; Calcimycin; Carbachol; Endothelium; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; | 1986 |
Relaxation of isolated human pulmonary muscle preparations with prostacyclin (PGI2) and its analogs.
Topics: Bronchi; Epoprostenol; Histamine; Humans; Iloprost; Indomethacin; Lung; Muscle Contraction; Muscle R | 1987 |
Mechanism underlying relaxations caused by prostaglandins and thromboxane A2 analog in isolated dog arteries.
Topics: Animals; Cerebral Arteries; Coronary Vessels; Dinoprost; Dogs; Female; In Vitro Techniques; Indometh | 1988 |
Calcitonin gene-related peptides relax guinea pig and rat gastric smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
Leukotriene D4 and platelet-activating factor-acether antagonists on allergic and arachidonic acid-induced reactions in guinea pig airways.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Guinea Pigs; Hypersensitivity; In Vitro Techniques; In | 1989 |
Endothelium-dependent relaxation of human basilar arteries.
Topics: Acetylcholine; Adult; Aged; Basilar Artery; Benzoquinones; Calcimycin; Child; Child, Preschool; Dose | 1989 |
Contraction followed by relaxation in response to hypoxia in the sheep isolated middle cerebral artery.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Cerebral Arteries; Endotheliu | 1989 |
Prostanoid involvement in the relaxation of in vitro mesenteric artery by bradykinin and des-Arg9-bradykinin.
Topics: Angiotensin II; Animals; Bradykinin; Cycloheximide; Dinoprostone; Epoprostenol; In Vitro Techniques; | 1989 |
Mechanisms of action of eperisone on isolated dog saphenous arteries and veins.
Topics: Animals; Arteries; Aspirin; Dogs; Drug Interactions; Electric Stimulation; Female; In Vitro Techniqu | 1989 |
Characterization of an endothelial 5-hydroxytryptamine (5-HT) receptor mediating relaxation of the porcine coronary artery.
Topics: Animals; Citalopram; Coronary Vessels; Corticosterone; Endothelium, Vascular; Gossypol; In Vitro Tec | 1989 |
Endothelium-dependent calcium-induced relaxation in the presence of Ca2+-antagonists in canine depolarized coronary arteries.
Topics: Animals; Calcium; Calcium Channel Blockers; Coronary Vessels; Dogs; Endothelium, Vascular; In Vitro | 1989 |
Mechanisms of endothelium-dependent vascular smooth muscle relaxation elicited by bradykinin and VIP.
Topics: Animals; Bradykinin; Cattle; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Indomethacin; Methylene | 1987 |
Beta-adrenoceptor desensitization in guinea-pig isolated trachea.
Topics: Animals; Autoradiography; Carbachol; Female; Fenoterol; Guinea Pigs; Hydrocortisone; In Vitro Techni | 1988 |
Beta agonist-induced desensitization in pig bronchus.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Airway Resistance; Animals; Bronchi; Colforsi | 1986 |
Relaxation of isolated mesenteric arteries by des-Arg9-bradykinin stimulation of B1 receptors.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; In Vitro Techniques; Indomethacin; Kinins; | 1986 |
Pharmacological evaluation of the beta-adrenoceptor agonist and thromboxane antagonist properties of N-substituted trimetoquinol analogues.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic beta-Agonists; Animal | 1987 |
Endothelium-dependent responses in autogenous femoral veins grafted into the arterial circulation of the dog.
Topics: Acetylcholine; Adenosine Diphosphate; Adrenergic alpha-Agonists; Animals; Arachidonic Acid; Arachido | 1987 |
Relaxant profile of synthetic atrial natriuretic factor on guinea-pig pulmonary tissues.
Topics: Airway Resistance; Anesthesia; Animals; Atrial Natriuretic Factor; Bronchi; Guinea Pigs; In Vitro Te | 1986 |
Relaxation of rabbit middle cerebral arteries in vitro by H1 histaminergic agonists is inhibited by indomethacin and tranylcypromine.
Topics: Animals; Cerebral Arteries; Dimaprit; In Vitro Techniques; Indomethacin; Male; Methylhistamines; Mus | 1988 |
Induction of vascular relaxation by hydroperoxides.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Chlorobenzoates; Endothelium; Hydroxide | 1986 |
Arachidonic acid-induced endothelial-dependent relaxations of canine coronary arteries: contribution of a cytochrome P-450-dependent pathway.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoflavones; beta-Naphthoflavone; Coronary Vessels; | 1987 |
Different sensitivities of arteries and veins to glyceryltrinitrate-induced relaxation and tolerance: an "in vitro" study on isolated vessels from rabbits.
Topics: Animals; Arteries; Cysteine; Drug Tolerance; In Vitro Techniques; Indomethacin; Muscle Relaxation; M | 1987 |
Pharmacological modulation of bradykinin-, acetylcholine- and calcium ionophore A23187-induced relaxation of rabbit pulmonary arterial segments.
Topics: Acetylcholine; Animals; Bradykinin; Calcimycin; In Vitro Techniques; Indomethacin; Male; Muscle Rela | 1987 |
Impaired endothelium-dependent relaxations in rabbits subjected to aortic coarctation hypertension.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Coarctation; Calcimycin; Carotid A | 1987 |
Effects of dietary supplementation with cod-liver oil on endothelium-dependent responses in porcine coronary arteries.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Co | 1987 |
Relaxation of guinea-pig tracheal smooth muscle to arachidonate is converted to contraction following epithelium removal.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Epithelium; Guinea Pigs; In Vitro Techniques; Indometh | 1987 |
Arachidonic acid metabolites and airway epithelium-dependent relaxant factor.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non | 1987 |
Possible prostacyclin involvement on disparate tonic responses to "in vitro" norepinephrine in circular and in longitudinal preparations from rat thoracic aorta.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Dose-Re | 1987 |
The relaxant and spasmogenic effects of some xanthine derivatives acting on guinea-pig isolated trachealis muscle.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Colforsin; Egtazic Acid; Female; Guinea Pigs; In Vitro Te | 1988 |
Small fibronectin fragments induce endothelium-dependent vascular relaxations.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Fibronectins; Hemoglobins; In Vitro Techniques; Indom | 1988 |
Pharmacology of natural compounds. I. Smooth muscle relaxant activity induced by a Ginkgo biloba L. extract on guinea-pig trachea.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Musc | 1988 |
Relaxation by prostacyclin (PGI2) of human, dog and rabbit femoral artery strips. Interspecies difference.
Topics: Animals; Dinoprost; Dogs; Drug Synergism; Femoral Artery; Humans; In Vitro Techniques; Indomethacin; | 1988 |
Lysolecithins as endothelium-dependent vascular smooth muscle relaxants that differ from endothelium-derived relaxing factor (nitric oxide)
Topics: Acetylcholine; Animals; Biological Factors; Dose-Response Relationship, Drug; Endothelium, Vascular; | 1988 |
Effects of indomethacin on non-adrenergic, non-cholinergic motility of stomach and small intestine.
Topics: Animals; Autonomic Nervous System; Cats; Electric Stimulation; Female; Gastrointestinal Motility; In | 1988 |
The response of isolated guinea-pig aorta to amrinone.
Topics: Adenosine; Adenosine Deaminase; Amrinone; Animals; Aorta, Thoracic; Female; Guinea Pigs; In Vitro Te | 1988 |
Different time courses of bovine iris sphincter and dilator muscles after stimulation.
Topics: Animals; Cattle; Electric Stimulation; Electromyography; In Vitro Techniques; Indomethacin; Iris; Mu | 1987 |
Endothelium-dependent relaxations in human arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Adolescent; Adult; Aged; Arteries; Dinoprost; Endothelium; Hum | 1987 |
Platelet-activating factor-acether-induced relaxation of guinea pig airway muscle: role of prostaglandin E2 and the epithelium.
Topics: Acetylcholine; Animals; Aspirin; Dinoprostone; Epithelium; Guinea Pigs; Histamine; In Vitro Techniqu | 1987 |
Endothelium-derived relaxing factor is a selective relaxant of vascular smooth muscle.
Topics: Animals; Aorta; Biological Products; Cattle; Cells, Cultured; Endothelium, Vascular; Guinea Pigs; In | 1987 |
Relaxant effects of vasoactive intestinal peptide and peptide histidine isoleucine in human and bovine pulmonary arteries.
Topics: Adenosine Triphosphate; Animals; Atropine; Cattle; Endothelium; Humans; In Vitro Techniques; Indomet | 1987 |
Simultaneous measurement of force and calcium uptake during acetylcholine-induced endothelium-dependent relaxation of rabbit thoracic aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atropine; Calcium; Endothelium; In Vitro Techniques; Indome | 1987 |
Suppression by 5'-methylthioadenosine of histamine or leukotriene-induced contraction in isolated guinea pig tracheal rings.
Topics: Adenosine; Animals; Deoxyadenosines; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Hi | 1986 |
Mechanisms of histamine-induced relaxation in isolated monkey and dog coronary arteries.
Topics: Animals; Benzoquinones; Chlorpheniramine; Cimetidine; Coronary Vessels; Dogs; Female; Histamine; Ind | 1986 |
Endothelium-dependent relaxation of human pulmonary arteries.
Topics: Acetylcholine; Adenosine Triphosphate; Endothelium; Humans; Indomethacin; Muscle Contraction; Muscle | 1987 |
Interaction between non-steroidal antiinflammatory agents and sodium salicylate in the relaxant response of dog renal arteries to angiotensin II.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Dogs; Epoprostenol; Female; Ibuprofen; In Vitro T | 1985 |
Effects of the C5a anaphylatoxin and its relationship to cyclo-oxygenase metabolites in rabbit vascular strips.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Complement C5; Complement C5a; Epoprostenol; Humans; In Vitro | 1985 |
Leukotriene D4 relaxes canine renal and superior mesenteric arteries.
Topics: Acetylcholine; Animals; Chromones; Dogs; Dose-Response Relationship, Drug; Female; Indomethacin; Mal | 1985 |
Ouabain inhibits endothelium-dependent relaxations to arachidonic acid in canine coronary arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Coronary Vessels | 1985 |
Alterations of arachidonic acid metabolism modulate adenosine relaxation in isolated coronary arteries.
Topics: Adenosine; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Coronary Vessels; Dogs; Enzyme Inhi | 1985 |
Relaxant effect of phospholipase A2 from Vipera russelli snake venom on rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; | 1985 |