indomethacin has been researched along with Muscle Contraction in 1149 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Further, we applied a range of concentrations of ADO (10(-7)-10(-5) M) extraluminally, (to mimic muscle contraction) in the absence and presence of L-NAME (NO synthase inhibitor), indomethacin (INDO, cyclooxygenase inhibitor) and L-NAME + INDO and observed the response of 2A arterioles." | 7.80 | Prostaglandins induce vasodilatation of the microvasculature during muscle contraction and induce vasodilatation independent of adenosine. ( Dodd, JD; Foster, AJ; Inch, KA; Muckle, FR; Murrant, CL; Ruiz, DA; Scholl, JH; Simpson, JA, 2014) |
| "The purpose of the present study was to investigate the effects of vitamin K(1) on vascular smooth muscle contractility in response to phenylephrine (Phe) during hypoxia." | 7.71 | Vitamin K(1) prevents the effect of hypoxia on phenylephrine-induced contraction in the carotid artery. ( de Oliveira, AM; Mingatto, FE; Tirapelli, CR, 2002) |
| "The aim of this study was to determine whether the prostaglandin synthase inhibitor indomethacin reverses the inflammation and abnormal gallbladder contractility that occur after common bile duct ligation (CBDL), a model of acute cholecystitis." | 7.71 | Effect of indomethacin on gallbladder inflammation and contractility during acute cholecystitis. ( Bartula, LL; James, AN; Myers, SI; Parkman, HP; Ryan, JP; Thomas, RM, 2001) |
| " Then after pretreatment, we tested indomethacin (10(-5) M), N-nitro-L-arginine (L-NNA, 10(-5) M) and nicorandil (10(-5) M) each separately, then each of the three substances together with hypoxia." | 7.70 | 5-hydroxytryptamine induces vasoconstriction of the human umbilical artery: effects of hypoxia and nicorandil. ( Tiritilli, A, 2000) |
| "The aim of this study was to investigate the effect of hypercholesterolemia on the angiotensin II-induced contractions in the isolated aorta and iliac artery of the rabbit, with respect to the role of arachidonate metabolites." | 7.69 | Effects of hypercholesterolemia on the contractions to angiotensin II in the isolated aorta and iliac artery of the rabbit: role of arachidonic acid metabolites. ( Dam, JP; Porsius, AJ; Post, MJ; Riezebos, J; Vleeming, W; Wemer, J, 1997) |
| "Repeated administration of indomethacin delays the healing of acetic acid-induced gastric ulcers in rats, but the underlying mechanism remains unclear." | 7.68 | Mechanism by which indomethacin delays gastric ulcer healing in the rat: inhibited contraction of the ulcer base. ( Ogihara, Y; Okabe, S, 1993) |
| "Airway reactivity to histamine was determined in a group of non-asthmatic and asthmatic patients prior to thoracotomy." | 7.67 | Human isolated bronchial muscle preparations from asthmatic patients: effects of indomethacin and contractile agonists. ( Benveniste, J; Brink, C; Cerrina, J; Haye-Legrande, I; Labat, C; Raffestin, B, 1989) |
| "The effects of indomethacin and meclofenamate on active hyperemia following sustained, maximal isometric contractions were studied in free-flowing dog gracilis muscles." | 7.67 | Indomethacin and meclofenamate potentiation of skeletal muscle active hyperemia. ( Klabunde, RE; Rankin, RS, 1985) |
| " (+/-)-alpha-(Benzoylamino)-4-[2-(diethylamino)-ethoxy]-NN-di-propylbenzen-propanamid (tiropramide, CR 605), a new tyrosine derivative with antispastic properties, increases cAMP concentrations within the same dose range that produces smooth muscle relaxation with or without carbachol (0." | 7.66 | Mechanism of smooth muscle relaxation by tiropramide. ( Cifarelli, A; Setnikar, I; Vidal y Plana, RR, 1981) |
| " 9 The results are also discussed in relation to the genesis of aspirin-induced asthma in man." | 7.66 | Spontaneous activity in the trachea of dogs treated with indomethacin: an experimental model for aspirin-related asthma. ( Ito, Y; Tajima, K, 1981) |
| "Indomethacin is an effective inhibitor of prostaglandin synthetase and has recently been demonstrated to inhibit inflammatory fluid secretion into the gallbladder in experimental cholecystitis." | 5.26 | Indomethacin intravenously--a new way for effective relief of biliary pain: a double-blind study in man. ( Jansson, R; Svanvik, J; Thornell, E, 1981) |
| " Further, we applied a range of concentrations of ADO (10(-7)-10(-5) M) extraluminally, (to mimic muscle contraction) in the absence and presence of L-NAME (NO synthase inhibitor), indomethacin (INDO, cyclooxygenase inhibitor) and L-NAME + INDO and observed the response of 2A arterioles." | 3.80 | Prostaglandins induce vasodilatation of the microvasculature during muscle contraction and induce vasodilatation independent of adenosine. ( Dodd, JD; Foster, AJ; Inch, KA; Muckle, FR; Murrant, CL; Ruiz, DA; Scholl, JH; Simpson, JA, 2014) |
| "The aim of the study was to evaluate the antiulcer activity of Linum usitatissimum fixed oil against aspirin-, indomethacin-, ethanol-, reserpine-, serotonin- and stress-induced gastric ulceration in rats and histamine-induced gastric ulceration in guinea pigs." | 3.76 | Evaluation of antiulcer and antisecretory potential of Linum usitatissimum fixed oil and possible mechanism of action. ( Kaithwas, G; Majumdar, DK, 2010) |
| " To determine the beneficial effects of statins on the airway hyperresponsiveness, a characteristic feature of allergic bronchial asthma, the effect of systemic treatment with lovastatin on antigen-induced bronchial smooth muscle hyperresponsiveness was investigated in mice." | 3.74 | Inhibition of antigen-induced bronchial smooth muscle hyperresponsiveness by lovastatin in mice. ( Chiba, Y; Misawa, M; Sato, S, 2008) |
| "Strips from rabbits with colitis induced by 2,4,6-trinitrobenzenesulfonic acid (TNBS) were subjected to electrical field stimulation." | 3.72 | Mechanisms involved in the loss of excitatory post-stimulus responses by inflammation. ( Depoortere, I; Peeters, TL; Thielemans, L; Thijs, T, 2003) |
| "The role of muscle contraction, prostanoids, nitric oxide and adenosine in the regulation of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF) and endothelial cell proliferative compounds in skeletal muscle cell cultures was examined." | 3.72 | Regulation of VEGF and bFGF mRNA expression and other proliferative compounds in skeletal muscle cells. ( Hellsten, Y; Jensen, L; Schjerling, P, 2004) |
| "The purpose of the present study was to investigate the effects of vitamin K(1) on vascular smooth muscle contractility in response to phenylephrine (Phe) during hypoxia." | 3.71 | Vitamin K(1) prevents the effect of hypoxia on phenylephrine-induced contraction in the carotid artery. ( de Oliveira, AM; Mingatto, FE; Tirapelli, CR, 2002) |
| "The aim of this study was to determine whether the prostaglandin synthase inhibitor indomethacin reverses the inflammation and abnormal gallbladder contractility that occur after common bile duct ligation (CBDL), a model of acute cholecystitis." | 3.71 | Effect of indomethacin on gallbladder inflammation and contractility during acute cholecystitis. ( Bartula, LL; James, AN; Myers, SI; Parkman, HP; Ryan, JP; Thomas, RM, 2001) |
| " Anaphylaxis-induced contractions of proximal and distal tracheal segments isolated from 14-day ovalbumin (OA)-sensitized rats were studied." | 3.70 | Contractile responses of proximal and distal trachea segments isolated from rats subjected to immunological stimulation: role of connective tissue mast cells. ( da Silva, ZL; de Lima, WT, 1998) |
| " Pharmacologic studies were performed by pretreating guinea pig tracheal tissue with drugs known to modulate smooth muscle contraction: atropine, indomethacin, pyrilamine, nordihydroguaiacetic acid, acivicin, trimethobenzoic acid and capsaicin." | 3.70 | Pharmacologic characterization of latex extracts by isolated guinea pig tracheal tissue. ( Goswami, S; Maayani, S; Rienzi, N; Schachter, EN; Zuskin, E, 1998) |
| " Then after pretreatment, we tested indomethacin (10(-5) M), N-nitro-L-arginine (L-NNA, 10(-5) M) and nicorandil (10(-5) M) each separately, then each of the three substances together with hypoxia." | 3.70 | 5-hydroxytryptamine induces vasoconstriction of the human umbilical artery: effects of hypoxia and nicorandil. ( Tiritilli, A, 2000) |
| " In order to examine whether K+ channels play a role in antigen-induced airway responses, the effect of K+ channel blockers on antigen-induced airway smooth muscle contraction and mediator release was examined in vitro in guinea-pigs actively sensitized with ovalbumin (OA)." | 3.69 | Involvement of apamin-sensitive K+ channels in antigen-induced spasm of guinea-pig isolated trachea. ( Ichinose, M; Inoue, H; Ishikawa, J; Maeyama, K; Miura, M; Nakajima, N; Shirato, K; Tomaki, M; Watanabe, T; Yamauchi, H, 1994) |
| "The aim of this study was to investigate the effect of hypercholesterolemia on the angiotensin II-induced contractions in the isolated aorta and iliac artery of the rabbit, with respect to the role of arachidonate metabolites." | 3.69 | Effects of hypercholesterolemia on the contractions to angiotensin II in the isolated aorta and iliac artery of the rabbit: role of arachidonic acid metabolites. ( Dam, JP; Porsius, AJ; Post, MJ; Riezebos, J; Vleeming, W; Wemer, J, 1997) |
| "We studied the effect of either 1) immunogenic inflammation caused by aerosolized ovalbumin or 2) neurogenic inflammation caused by aerosolized capsaicin in vivo on guinea pig tracheal smooth muscle (TSM) contractility in vitro." | 3.68 | Effect of airway inflammation on smooth muscle shortening and contractility in guinea pig trachealis. ( Arbetter, K; Leff, AR; Mitchell, RW; Ndukwu, IM; Solway, J, 1993) |
| "Repeated administration of indomethacin delays the healing of acetic acid-induced gastric ulcers in rats, but the underlying mechanism remains unclear." | 3.68 | Mechanism by which indomethacin delays gastric ulcer healing in the rat: inhibited contraction of the ulcer base. ( Ogihara, Y; Okabe, S, 1993) |
| "To evaluate the cellular mechanisms involved in hypoxic relaxation of airway smooth muscle, we investigated the effects of hypoxia on the behavior of third- and fourth-order porcine bronchial rings contracted with either carbachol or KCl." | 3.68 | Role of Ca2+ entry in the modulation of airway tone by hypoxia. ( Croxton, TL; Fernandes, LB; Hirshman, CA; Stuart-Smith, K, 1993) |
| " To determine the effect of the slow channel calcium blockers verapamil and diltiazem in vascular smooth muscle contraction during states of altered oxygenation, rat aortic rings with intact endothelium were contracted with norepinephrine (NE) or the thromboxane A2 mimic U46,619 and then exposed abruptly to anoxia (switch from 95% O2 to 95% N2) for 30 min and then reoxygenated (switch from 95% N2 to 95% O2)." | 3.68 | Slow channel calcium blockers attenuate reoxygenation-mediated vascular contraction, but augment anoxia-mediated vascular contraction. ( Haught, WH; Lawson, DL; Mehta, JL; Yang, BC, 1992) |
| " 3 The additional smooth muscle contraction stimulated by 5-HT was increased in the presence of the competitive substrate inhibitor for nitric oxide synthase, NG-nitro-L-arginine methyl ester (L-NAME, 100 microM)." | 3.68 | Endothelium-dependent contractile responses to 5-hydroxytryptamine in the rabbit basilar artery. ( Clark, AH; Garland, CJ; Seager, JM, 1992) |
| "Desensitization of alpha-adrenergic receptor-mediated smooth muscle contraction occur in aortas from New England Deaconess Hospital (NEDH) rats harboring pheochromocytoma (PHEO) and following chronic exposure to the alpha-adrenergic agonist phenylephrine in vitro." | 3.68 | Desensitization of alpha-adrenergic receptor-mediated smooth muscle contraction: role of the endothelium. ( Hiremath, AN; Hoffman, BB; Hu, ZW, 1991) |
| " This depression was not affected by pretreatment of tissues with propranolol, indomethacin or ouabain, or removal of epithelium, and BA at sufficient concentrations to cause muscle relaxation did not alter intracellular adenosine 3',5'-cyclic monophosphate contents." | 3.68 | Relaxation of canine airway smooth muscle by the heparin preservative benzyl alcohol. ( Chiyotani, A; Horii, S; Kanemura, T; Kobayashi, K; Sakai, N; Takizawa, T; Tamaoki, J, 1990) |
| "We evaluated the effects of a sublethal Escherichia coli endotoxemia with and without concomitant administration of indomethacin on diaphragmatic strength in an in vivo rat model." | 3.68 | Preventive effects of indomethacin on diaphragmatic contractile alterations in endotoxemic rats. ( Aubier, M; Boczkowski, J; Dureuil, B; Pariente, R, 1990) |
| "The temporal relationship between release of the mediators histamine and slow reacting substance of anaphylaxis (SRS-A) and smooth muscle contraction in response to antigen was examined using superfused tracheae from actively sensitized (ovalbumin) and reserpine-pretreated guinea pigs." | 3.67 | Studies on the relationship between contraction and mediator release produced by ovalbumin in superfused trachea isolated from the actively sensitized guinea pig. ( Buckner, CK; Fishleder, RI, 1984) |
| "The effects of substance P (SP) on smooth-muscle contractions induced by noradrenaline (NA) or by high- or low-frequency electrical stimulation (ES) were studied on isolated rat vas deferens and musculus anococcygeus." | 3.67 | Smooth-muscle effects of substance P. ( Todorov, S; Zamfirova, R, 1988) |
| "Airway reactivity to histamine was determined in a group of non-asthmatic and asthmatic patients prior to thoracotomy." | 3.67 | Human isolated bronchial muscle preparations from asthmatic patients: effects of indomethacin and contractile agonists. ( Benveniste, J; Brink, C; Cerrina, J; Haye-Legrande, I; Labat, C; Raffestin, B, 1989) |
| " The pharmacologic characteristics of the antigen-induced airway smooth muscle contraction in vitro were similar to those induced by arachidonic acid and the leukotrienes only in some respects but were clearly different from those induced by compound 48/80." | 3.67 | Pharmacological characterization of airway smooth muscle responses to antigen in ascaris-sensitive dogs. ( Davis, C; Kannan, L; Kannan, MS; Ladenius, AR; Sankaranarayanan, A, 1986) |
| "The effects of indomethacin and meclofenamate on active hyperemia following sustained, maximal isometric contractions were studied in free-flowing dog gracilis muscles." | 3.67 | Indomethacin and meclofenamate potentiation of skeletal muscle active hyperemia. ( Klabunde, RE; Rankin, RS, 1985) |
| " (+/-)-alpha-(Benzoylamino)-4-[2-(diethylamino)-ethoxy]-NN-di-propylbenzen-propanamid (tiropramide, CR 605), a new tyrosine derivative with antispastic properties, increases cAMP concentrations within the same dose range that produces smooth muscle relaxation with or without carbachol (0." | 3.66 | Mechanism of smooth muscle relaxation by tiropramide. ( Cifarelli, A; Setnikar, I; Vidal y Plana, RR, 1981) |
| " The resulting muscle contraction could not be inhibited by atropine, phentolamine or quinidine." | 3.66 | Neuromuscular transmission in the corpus-fundus of the urinary bladder. An in vitro study in the cat. ( Nergårdh, A, 1981) |
| " Eicosatetraynoic acid (50 microM), nordihydroguairetic acid (50 microM) and QUIN (10 microM) do not exert significant inhibitory effects at the level of smooth muscle relaxation mechanisms as isoproterenol-induced relaxation was resistant to inhibition by these agents." | 3.66 | Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism. ( Peach, MJ; Singer, HA, 1983) |
| "1 Indomethacin enhances muscle contraction to histamine in the pig isolated trachea." | 3.66 | The effect of mixed inhibitors of cyclo-oxygenase and lipoxygenase on the indomethacin-induced hyper-reactivity in the isolated trachea of the pig. ( Mitchell, HW, 1982) |
| " 9 The results are also discussed in relation to the genesis of aspirin-induced asthma in man." | 3.66 | Spontaneous activity in the trachea of dogs treated with indomethacin: an experimental model for aspirin-related asthma. ( Ito, Y; Tajima, K, 1981) |
| "Cotreatment with omeprazole did not reduce indomethacin-induced intestinal bleeding." | 1.42 | Suppression of contractile activity in the small intestine by indomethacin and omeprazole. ( Bhattarai, D; Dial, EJ; Lichtenberger, LM; Phan, TM; Uray, K, 2015) |
| "Thiamine deficiency is a condition that is known to cause damage to the nervous and cardiovascular systems because it interferes with cellular metabolism." | 1.40 | Thiamine deficiency leads to reduced nitric oxide production and vascular dysfunction in rats. ( Capettini, LS; Cruz, JS; Gioda, CR; Lemos, VS, 2014) |
| "Pretreatment with indomethacin at both concentrations did not result in a significant reduction in the maximum contraction compared with the control." | 1.35 | In vitro effects of the cyclooxygenase inhibitor indomethacin and of the phospholipase-C inhibitor U-73122 on carbachol-induced contractions of porcine detrusor muscle. ( Badawi, JK; Bross, S; Seja, T, 2008) |
| "Peritonitis was induced by cecal ligation and puncture in 8 rats." | 1.35 | Alterations in spontaneous contractions of rat ileum and jejunum after peritonitis. ( Altun, A; Bagcivan, I; Durmus, N; Guney, C; Karadas, B; Kaya, T; Koyluoglu, G, 2008) |
| "Indomethacin treatment attenuated the dilation in paired (-33 +/- 5%) but not unpaired (-6 +/- 4%) arterioles." | 1.35 | Functional vasodilation in the rat spinotrapezius muscle: role of nitric oxide, prostanoids and epoxyeicosatrienoic acids. ( Hester, RL; Naik, JS; Xiang, L, 2008) |
| "Nicotine was applied to preparations at varying concentrations." | 1.34 | Enhancement effects of nicotine on neurogenic contractile responses in rabbit gastric fundus. ( Dileköz, E; Ilhan, SO; Oztürk, GS; Sarioglu, Y; Vural, IM, 2007) |
| "Indomethacin was used to evaluate the influence of prostanoids on the RCs." | 1.34 | Endothelial nitric oxide has inhibitory effects on rhythmic contractions in the aortas of sinoaortic deafferented rats. ( Bendhack, LM; Rocha, ML, 2007) |
| "The oxytocin responses were similar at all lengths." | 1.33 | Shortening increases spontaneous contractility in myometrium from pregnant women at term. ( Gibbs, SG; Guy, SR; Horowitz, GM; Hurd, WW; Ventolini, G, 2005) |
| "Trandolapril treatment decreased the Ang II and Phe potencies in carotid arteries, but did not affect the maximal response." | 1.33 | B(2)-receptor modulation of the reactivity to phenylephrine and angiotensin II in the carotid artery of normotensive rats after trandolapril treatment. ( Accorsi-Mendonça, D; Corrêa, FM; Oliveira, AM, 2006) |
| " Our results suggest that the association between an antimuscarinic drug and an antagonist of P2X purinoceptors such as suramin might be helpful to reduce the therapeutic dosage of the antimuscarinic drug, along with its side effects." | 1.33 | Altered neurogenic and mechanical responses to acetylcholine, ATP and substance P in detrusor from rat with outlet obstruction. ( Pinna, C; Puglisi, L; Sanvito, P, 2006) |
| "Cadmium (Cd) toxicity was produced in male rats to study the role of cholinoceptors in Cd-induced endothelial dysfunction." | 1.32 | Involvement of cholinoceptors in cadmium-induced endothelial dysfunction. ( Alkan, Z; Bilgen, I; Cirrik, S; Edremitlioğlu, M; Oner, G, 2003) |
| "Pre-treatment with indomethacin, but not with l-NAME, prevented the relaxation induced by alpha-CGRP in pulmonary arteries suggesting that prostaglandins but not nitric oxide (NO) are involved in the intracellular signal transduction pathway." | 1.32 | Effects of alpha calcitonin gene-related peptide in human bronchial smooth muscle and pulmonary artery. ( Amadesi, S; Dinh, QT; Fischer, A; Geppetti, P; Groneberg, DA; Harrison, S; McGregor, GP; Springer, J; Trevisani, M, 2004) |
| " The dosage of 230 mg/kg of nicotinamide given intraperitoneally 15 min before STZ administration (65 mg/kg i." | 1.32 | Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats. ( Kamata, K; Kobayashi, T; Matsumoto, T; Wakabayashi, K, 2004) |
| "Indomethacin treatment abolished these effects." | 1.32 | Prostanoids contribute to the oxygen-dependent regulation of vascular tone of human umbilical vein. ( Mildenberger, E; Siegel, G; Versmold, HT, 2004) |
| "Bradykinin receptors have been divided into B1 and B2 subtypes." | 1.32 | BK2 but not BK1 receptors mediating contractile response in human umbilical arteries: role of thromboxane A2. ( Duret, JF; El Habach, T; Haury, L; Tiritilli, A, 2004) |
| " There was a reduction in PGE2 levels on chronic administration of celecoxib in DSS-treated animals." | 1.32 | Aggravation of inflammatory bowel disease by cyclooxygenase-2 inhibitors in rats. ( Jain, NK; Kulkarni, SK; Patil, CS; Singh, VP, 2004) |
| "Late pregnancy is characterized by a significantly diminished systolic blood pressure in conscious rats (-17 mmHg, P < 0." | 1.31 | Endothelium and aortic contraction to endothelin-1 in the pregnant rat. ( Dièye, AM; Gairard, A, 2000) |
| "Prucalopride did not cause relevant inhibition of 5-HT(2A), 5-HT(2B), or 5-HT(3), motilin or cholecystokinin (CCK(1)) receptor-mediated contractions, nor nicotinic or muscarinic acetylcholine receptor-mediated contractions, up to 10 microM." | 1.31 | The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. ( Bosmans, JP; Briejer, MR; Heylen, L; Jurzak, M; Leysen, JE; Prins, NH; Schuurkes, JA; Van Daele, P, 2001) |
| " The dose-response curve for the acetylcholine-induced relaxation was slightly, but significantly attenuated in diabetic mice." | 1.31 | Contractile responses in spontaneously diabetic mice. I. Involvement of superoxide anion in enhanced contractile response of aorta to norepinephrine in C57BL/KsJ(db/db) mice. ( Kamata, K; Kanie, N, 2000) |
| "Taking into consideration the effect of septic shock on releasing various mediators, the present study was undertaken in an attempt to elucidate the effect of endotoxin on naloxone-induced withdrawal contractions in the guinea-pig isolated ileum." | 1.31 | Effects of endotoxin-induced shock on withdrawal contractions in the Guinea-pig isolated ileum. ( Fatehi, M; Fatehi-Hassanabad, Z; Tanomand, A, 2002) |
| "When histamine was administered to the mucosal side of epithelium-denuded segments, the contractions were twice as high in proximal than in distal parts (3057 vs." | 1.31 | Differential responsiveness of proximal and distal parts of isolated guinea pig trachea. ( Bloksma, N; De Clerck, F; Folkerts, G; Kloek, J; Nijkamp, F, 2002) |
| "The indomethacin effect was eliminated by denuding the endothelium or by inhibiting cyclic nucleotide phosphodiesterase activity." | 1.30 | Regional differentiation in the rat aorta: effects of cyclooxygenase inhibitors. ( Sang, JC; Schachter, D, 1997) |
| "6." | 1.30 | Endothelin receptor-mediated Ca2+ mobilization and contraction in bovine oviductal arteries: comparison with noradrenaline and potassium. ( Costa, G; García-Pascual, A; Jimenez, E; Labadía, A; Triguero, D, 1997) |
| "In indomethacin-treated rats, NKA further increased motility but decreased indomethacin-stimulated bicarbonate secretion by 70%." | 1.30 | Neurokinin A increases duodenal mucosal permeability, bicarbonate secretion, and fluid output in the rat. ( Flemström, G; Hällgren, A; Hellgren, S; Hellström, PM; Lördal, M; Nylander, O, 1997) |
| "Pretreatment with indomethacin (cyclooxygenase inhibitor, 1 x 10[-5] M) had no effect on contractile responses to phenylephrine in rings from both groups of rats." | 1.30 | Enhanced endothelial nitric oxide activity contributes to the reduced responsiveness of vascular alpha1-adrenoceptors following aortic barodenervation. ( Abdel-Galil, AG; Daabees, TT; El-Gowelli, HM; El-Mas, MM, 1997) |
| "Fluoxetine treatment did not modify the binding parameters of [3H]-prazosin to vas deferens." | 1.30 | Long-term treatment with fluoxetine associates with peripheral effects on rat vas deferens contractility. ( Borda, E; Busch, L; Wald, M, 1999) |
| "Indomethacin pretreatment of primary and GP8 cells turned vasorelaxation into contraction while N(omega)-nitro-L-arginine pretreatment decreased the vasorelaxation induced by primary, but not by GP8 cells." | 1.30 | Vasoactive substances produced by cultured rat brain endothelial cells. ( Deli, MA; Gecse, A; Kis, B; Krizbai, IA; Mezei, Z; Papp, JG; Pataricza, J; Szabó, CA; Telegdy, G, 1999) |
| "Chronic hypertension is associated with impaired endothelial function [i." | 1.29 | Effect of cilazapril and indomethacin on endothelial dysfunction in the aortas of spontaneously hypertensive rats. ( Gräser, T; Kauser, K; Rubanyi, GM, 1993) |
| "Indomethacin treatment did not affect endothelium-dependent relaxation in the control solution but partially restored the response to ACh in elevated glucose." | 1.29 | Magnesium modulates endothelial dysfunction produced by elevated glucose incubation. ( Duhault, J; Félétou, M; Rasetti, C, 1994) |
| "Sepsis was induced by cecal ligation and puncture (CLP)." | 1.29 | Alterations of ex vivo vascular reactivity in intraperitoneal sepsis. ( Chen, SJ; Wu, CC; Yen, MH, 1994) |
| " When the endothelium was removed, however, the dose-response curves of both groups of rats were shifted to the left with an increase in maximum responses and they were no longer significantly different (max." | 1.29 | Effect of swimming on vascular reactivity to phenylephrine and KC1 in male rats. ( Jansakul, C, 1995) |
| "Previous studies indicate that anoxia results in vascular smooth muscle contraction, and this phenomenon is mediated in part by a decrease in release of endothelium-derived relaxing factor (EDRF)." | 1.29 | Platelets enhance anoxic contraction of rat aortic rings through platelet-activating factor-dependent mechanism. ( Chandna, VK; Lawson, DL; Mehta, JL; Yang, BC, 1993) |
| "Indomethacin treatment abolished the influence of the epithelium on ovalbumin-induced tracheal contraction." | 1.29 | Pharmacologic modulation of the influence of the epithelium on immunologic- and nonimmunologic-induced histamine release and contraction in guinea pig superfused tracheal strips. ( Buckner, CK; Conklin, R; Doran, O; Fishleder, RI; Graziano, FM; Will, JA, 1993) |
| "Etodolac was found to have no effect on 5-lipoxygenase activity." | 1.29 | Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs. ( Hamada, K; Inoue, K; Kimura, K; Shibata, Y; Ueda, F, 1994) |
| "Sulprostone was more potent than PGE2 indicating that the EP3 receptor was involved." | 1.29 | Effects of exogenous and endogenous prostaglandins on the fast phase of contraction of the guinea-pig vas deferens produced by electrical field stimulation. ( Christian, HC; Poyser, NL, 1994) |
| "Indomethacin was without effect in arteries and veins." | 1.29 | Endothelin receptors mediating functional responses in human small arteries and veins. ( Riezebos, J; Vallance, PJ; Watts, IS, 1994) |
| "Bradykinin relaxation was nearly completely or completely abolished in endothelium-denuded preparations and, in its place, there was often a small contraction." | 1.29 | Occurrence of endothelium-derived relaxing factor--nitric oxide in the lamb ductus arteriosus. ( Coceani, F; Kelsey, L; Seidlitz, E, 1994) |
| "Pretreatment with indomethacin (5 mg/kg, i." | 1.29 | Different modes of endothelin-1 action in pressor response in vivo and pulmonary parenchymal contraction in vitro in the guinea pig. ( Beppu, S; Matsuda, H; Miyatake, K; Ohmori, F, 1993) |
| "Placental vessels of women with gestational diabetes were found to undergo a significantly larger contraction than normal vessels when exposed to posthypoxic reoxygenation or micromolar concentrations of hydrogen peroxide." | 1.29 | Gestational diabetes alters human placental vascular responses to changes in oxygen tension. ( Figueroa, R; Omar, HA; Tejani, N; Wolin, MS, 1993) |
| "Indomethacin (1 microM) was found to produce approximately a 100% increase in the cholinergic response." | 1.29 | Prejunctional inhibition of cholinergic responses by prostaglandin E2 in human bronchi. ( Conanan, ND; Ellis, JL, 1996) |
| "3." | 1.29 | P2-purinoceptors mediating spasm of the isolated uterus of the non-pregnant guinea-pig. ( Hollingsworth, M; Piper, AS, 1996) |
| "Pravadoline was also inhibitory in the MVD." | 1.28 | Antinociceptive (aminoalkyl)indoles. ( Bell, MR; D'Ambra, TE; Daum, SJ; Eissenstat, MA; Herrmann, JL; Hlasta, DJ; Kumar, V; Philion, RE; Rosi, D; Wetzel, JR, 1991) |
| " Dose-response curves of epithelium-denuded tracheas were shifted to the left by approximately one order of magnitude." | 1.28 | Endothelins constrict guinea pig tracheas by multiple mechanisms. ( Hasegawa, S; Hirata, F; Matsumoto, H; Ninomiya, H; Nomura, A; Ohse, H; Saotome, M; Uchida, Y, 1992) |
| "3." | 1.28 | Potassium channel activation in vascular smooth muscle. ( Emden, J; Mironneau, J; Siegel, G; Stock, G; Wenzel, K, 1992) |
| "Treatment with indomethacin (2." | 1.28 | Isolated pulmonary resistance vessels from fetal lambs. Contractile behavior and responses to indomethacin and endothelin-1. ( Coceani, F; Wang, Y, 1992) |
| "1." | 1.28 | Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in alpha-adrenoceptor responsiveness with age and disease in isolated tissues. ( Christ, GJ; Maayani, S; Melman, A; Valcic, M, 1990) |
| "Treatment with indomethacin potentiated the contractile response of the arteries and reversed the relaxant response of veins to a contraction." | 1.28 | Comparison of responses to angiotensin II of dog mesenteric arteries and veins. ( Toda, N; Yamazaki, M, 1991) |
| "Treatment with indomethacin slightly potentiated the contractions induced by PGF2 alpha in mesenteric arteries." | 1.28 | Regional differences in the prostanoid receptors mediating prostaglandin F2 alpha-induced contractions of cat isolated arteries. ( Nakajima, M; Ueda, M, 1990) |
| "Ebselen is a new anti-inflammatory drug with a wide spectrum of pharmacological activities." | 1.28 | Ebselen inhibits contractile responses of guinea-pig parenchymal lung strips. ( Bast, A; Leurs, R; Timmerman, H, 1990) |
| " Preincubation of rat aorta with 10 microM SQ 29,548, a "selective" antagonist of thromboxane A2/prostaglandin H2 (TP) receptors, caused a rightward shift in the dose-response curve and a reduction in the maximal response to endothelin-1." | 1.28 | Role of thromboxane A2/prostaglandin H2 receptor in the vasoconstrictor response of rat aorta to endothelin. ( Mok, LL; Reynolds, EE, 1990) |
| "Pretreatment with lorglumide caused a dose-dependent rightward shift of the dose-response curve, indicating competitive antagonism." | 1.28 | Cholecystokinin causes contraction of the pupillary sphincter in monkeys but not in cats, rabbits, rats and guinea-pigs: antagonism by lorglumide. ( Almegård, B; Andersson, SE; Bill, A, 1990) |
| "We performed three consecutive dose-response curves to rapid intravenous infusions of substance P (SP) in anesthetized, mechanically ventilated guinea pigs." | 1.28 | Enhanced airway responses to substance P after repeated challenge in guinea pigs. ( Drazen, JM; Shore, SA, 1989) |
| "3." | 1.28 | Multiple mechanisms in the motor responses of the guinea-pig isolated urinary bladder to bradykinin. ( Cecconi, R; Geppetti, P; Giuliani, S; Maggi, CA; Meli, A; Patacchini, R; Santicioli, P, 1989) |
| " Dose-response curves with either arecoline or histamine on isolated tracheae from these animals display increased maximal contractions, and decreased EC50 values." | 1.28 | Endotoxin-induced hyperreactivity of the guinea-pig isolated trachea coincides with decreased prostaglandin E2 production by the epithelial layer. ( Engels, F; Folkerts, G; Nijkamp, FP, 1989) |
| "Indomethacin pretreatment did not cause changes in responsiveness or sensitivity of lung parenchymal strips from normal or sensitized guinea-pigs to the agonists tested." | 1.28 | Modification by indomethacin of airway contractile responses in normal and sensitized guinea-pigs. ( Cortijo, J; Esplugues, J; Morcillo, EJ; Ortiz, JL; Pascual, R; Perpiñá, M; Sanz, C; Sarría, B, 1989) |
| "8 mM), the dose-response curve for ATP was shifted to the left in a parallel fashion at this concentration." | 1.28 | Low calcium and calcium antagonists potentiate the contraction of guinea-pig vas deferens induced by ATP: a permissive role for P2-purinoceptors. ( Furukawa, T; Morishita, H, 1989) |
| " In this indomethacin-treated preparation, when an intermittent dosing regimen was used, repeated exposure to either human or murine EGF-URO caused a persistent desensitization." | 1.28 | Contractile actions of epidermal growth factor-urogastrone in isolated smooth muscle preparations from guinea pig stomach: structure-activity relationships and comparison with the effects of human transforming growth factor-alpha. ( Hollenberg, MD; Itoh, H; Lederis, K; Muramatsu, I; Patel, P; Yang, SG, 1989) |
| " Cumulative dose-response effects of ovalbumin were obtained on paired parenchymal strips, one used as control and the other drug treated." | 1.27 | Pharmacological alteration of antigen-induced contraction of lung parenchymal strips isolated from the actively sensitized guinea pig. ( Buckner, CK; Busse, WW; Songsiridej, V, 1983) |
| "Etodolac (Ultradol) is a new tetrahydropyrano-indole derivative which has shown pronounced analgesic and antiinflammatory properties." | 1.27 | Comparative effects of etodolac, indomethacin, and benoxaprofen on icosanoid biosynthesis. ( Borgeat, P; Salari, H; Saura, C; Sirois, P, 1984) |
| "Theophylline and cAMP inhibit the X-ray contraction probably non-specifically." | 1.27 | Contractile reaction of isolated frog aorta after X-irradiation. ( Greimel, H; Michailov, MC; Prechter, I; Welscher, UE, 1983) |
| " In order to evaluate the role of arachidonic acid metabolites in the C3a response, dose-response curves for C3a-induced contractions of guinea pig lung strips were compared in the presence and absence of several inhibitors which block metabolism of arachidonic acid at relatively specific steps in the pathways." | 1.27 | C3a-induced contraction of guinea pig lung parenchyma: role of cyclooxygenase metabolites. ( Bloor, CM; Hugli, TE; Stimler, NP, 1983) |
| "Indomethacin pretreatment (14 microM, 30 min) potentiated the relaxation response in intact rings." | 1.27 | Endothelium-dependent relaxation of rabbit aorta. I. Relaxation stimulated by arachidonic acid. ( Peach, MJ; Singer, HA, 1983) |
| "Indomethacin treatment induced a qualitatively similar shifting of the concentration-response curves of noradrenaline and angiotensin II in some vessels: the concentration-response curves remained unchanged for the aorta, were slightly shifted to the left of the pulmonary artery, were markedly shifted to the left for the coeliac artery, and were shifted to the right for the femoral artery." | 1.27 | The importance of endogenous prostaglandins other than prostacyclin, for the modulation of contractility of some rabbit blood vessels. ( Förstermann, U; Hertting, G; Neufang, B, 1984) |
| "1 X EC50) of NA were calculated from dose-response curves." | 1.27 | Effects of cyclooxygenase inhibitors and PGI2 on the adrenergic contractions of isolated rabbit arteries. ( Hadházy, P; Magyar, K; Malomvölgyi, B, 1984) |
| "Byssinosis is an occupational respiratory disease contracted by cotton mill workers who inhale cotton mill dust." | 1.27 | Bioassays of smooth muscle contracting agents in cotton mill dust and bract extracts: arachidonic acid metabolites as possible mediators of the acute byssinotic reaction. ( Ainsworth, SK; Bray, VJ; Cordova-Salinas, M; Mundie, TG, 1983) |
| "Metyrapone was also a relaxant agent, and its action was greater at low than at high PO2." | 1.27 | Cytochrome P 450-linked monooxygenase: involvement in the lamb ductus arteriosus. ( Coceani, F; Hamilton, NC; Labuc, J; Olley, PM, 1984) |
| " In normal calcium Krebs solution, dose-response curves to histamine were markedly reduced by verapamil while acetylcholine responses were relatively unaffected." | 1.27 | The effect of prostaglandin E2 on histamine-stimulated calcium mobilization as a possible explanation for histamine tachyphylaxis in canine tracheal smooth muscle. ( Anderson, WH; Krzanowski, JJ; Polson, JB; Szentivanyi, A, 1983) |
| " In the order of potency L-648,051 greater than FPL-55712 greater than L-649,923, these agents antagonized contractions to LTD4 and produced parallel rightward shifts in the dose-response curves." | 1.27 | Leukotriene and anti-IgE induced contractions of human isolated trachea: studies with leukotriene receptor antagonists and a novel 5-lipoxygenase inhibitor. ( Charette, L; Denis, D; Jones, TR, 1988) |
| " A method that avoided tachyphylaxis encountered in prior investigations was developed for isometric measurement of multiple dose-response effects." | 1.27 | Parasympathetic involvement in PAF-induced contraction in canine trachealis in vivo. ( Leff, AR; Munoz, NM; Popovich, KJ; Shioya, T; Stimler-Gerard, NP; White, SR, 1987) |
| "Azelastine is a phthalazinone derivative with a wide spectrum of pharmacological activities." | 1.27 | Inhibition of cysteinyl-leukotriene production by azelastine and its biological significance. ( Achterrath-Tuckermann, U; Luck, W; Peskar, BA; Simmet, T; Szelenyi, I, 1988) |
| "Oxytocin was shown to exhibit high intrinsic contractile activity on isolated strips of detrusor muscle, where the maximum contractile amplitude was 12% greater than control responses to 1 microM carbachol." | 1.27 | Evidence for oxytocin receptors in the urinary bladder of the rabbit. ( Anderson, GF; Romine, MT, 1985) |
| "Arachidonic acid (AA) was used to induce contractions of guinea-pig tracheal and lung parenchymal preparations in the presence of indomethacin." | 1.27 | Pharmacological modulation of responses of guinea-pig airways contracted with arachidonic acid. ( Burka, JF, 1985) |
| " Cyclooxygenase inhibition with indomethacin displaced the dose-response curve to AA to the right but did not prevent the relaxant effects of the fatty acid." | 1.27 | Arachidonic acid-induced endothelial-dependent relaxations of canine coronary arteries: contribution of a cytochrome P-450-dependent pathway. ( Abraham, NG; Mullane, KM; Pinto, A, 1987) |
| "In normocapnic and deeply hypocapnic guinea-pig heart-lung-preparations (HLPs), dose-response relationships were estimated for the bronchoconstrictor and pulmonary hypertensive responses to histamine (H), 5 hydroxytryptamine (5HT), arachidonic acid (AA) and U-46619, a prostaglandin endoperoxide analogue acting on thromboxane (TXA2) receptors." | 1.27 | Arachidonic acid and pulmonary function in heart-lung-preparation of guinea-pig: modulation by PCO2. ( Argiolas, L; Bedetti, C; Carpi, A; Del Basso, P, 1987) |
| "Cumulative dose-response curves to leukotriene C4 (LTC4) and leukotriene D4 (LTD)4 were obtained on indomethacin (5 microM) treated isolated guinea pig tracheal spiral strips." | 1.27 | Pharmacological comparison of L-serine borate and glutathione as inhibitors of metabolism of LTC4 to LTD4 by the isolated guinea pig trachea. ( Hand, JM; Schwalm, SF, 1987) |
| " Isolated rings (circular preparations) obtained from rat thoracic aortae responded to increasing concentrations of NE with dose-dependent tonic enhancement, not significantly affected by the presence of indomethacin (10(-6)M); whereas, preincubation with phentolamine (10(-6)M), yohimbine (10(-7)M) or prazosin (10(-8)M), shifted significantly to the right points of the positive inotropic dose-response curve for NE." | 1.27 | Possible prostacyclin involvement on disparate tonic responses to "in vitro" norepinephrine in circular and in longitudinal preparations from rat thoracic aorta. ( Chaud, M; Franchi, AM; Gimeno, AL; Gimeno, MA, 1987) |
| "Caffeine-induced spasm was attenuated in a Ca2+-free medium containing EGTA (2 mM), modestly at first but subsequently more profoundly." | 1.27 | The relaxant and spasmogenic effects of some xanthine derivatives acting on guinea-pig isolated trachealis muscle. ( Boyle, JP; Cortijo, J; Curtis-Prior, PB; Davies, JM; Foster, RW; Hofer, P; Small, RC, 1988) |
| "Histamine tachyphylaxis was also studied both in the presence and in the absence of indomethacin in tracheal smooth muscle strips obtained from seven additional dogs." | 1.27 | Histamine tachyphylaxis in canine airways despite prostaglandin synthesis inhibition. ( Antol, PJ; Gunst, SJ; Hyatt, RE, 1988) |
| "Nifedipine was more potent in inhibiting the contraction to K+ and serotonin in WKY diabetic arteries as compared with WKY controls." | 1.27 | Effect of diabetes on vascular smooth muscle function in normotensive and spontaneously hypertensive rat mesenteric artery. ( Agrawal, DK; McNeill, JH, 1987) |
| "Indomethacin pretreatment enhanced the capacity of PGD2 to potentiate cholinergic-induced contraction in normal but not in ovalbumin-sensitized guinea-pig." | 1.27 | Prostaglandin D2 (PGD2) potentiates cholinergic responsiveness in guinea-pig trachea. ( Berti, F; Brunelli, G; Daffonchio, L; Fabbri, L; Mapp, C; Omini, C, 1986) |
| "Histamine concentration-effect curves were obtained using either an individual or cumulative dosing method." | 1.27 | Histamine contraction of isolated human airway muscle preparations: role of prostaglandins. ( Bayol, A; Benveniste, J; Boullet, C; Brink, C; Cerrina, J; Haye-Legrand, I; Labat, C; Raffestin, B, 1986) |
| "Treatment with indomethacin attenuated the contraction-induced increase in mean arterial pressure and left ventricular dP/dt by 76% and 86%, respectively." | 1.27 | Prostaglandins contribute to cardiovascular reflexes evoked by static muscular contraction. ( Longhurst, JC; Maruoka, Y; Stebbins, CL, 1986) |
| "Pretreatment with milrinone more than doubled the mean time to fatigue (10." | 1.27 | Effects of milrinone on contractility of the rat diaphragm in vitro. ( Miller, MJ; Rossing, TH; Shannon, K, 1987) |
| " Cimetidine shifted the dose-response curve for histamine to the right, but chlorpheniramine did not alter the response." | 1.27 | Mechanisms of histamine-induced relaxation in isolated monkey and dog coronary arteries. ( Toda, N, 1986) |
| "Treatment with indomethacin, propanolol, and ouabain did not alter the potentiating effect of temperature on contractions to norepinephrine in ground squirrel femoral arteries." | 1.27 | Effect of cooling on vascular smooth muscle from the thirteen-lined ground squirrel. ( Harker, CT; Webb, RC, 1987) |
| "Indomethacin treatment reduced the potency of LTD4 and increased maximal contractile responses in most tissues." | 1.27 | Influences of gender and maturation on responses of guinea-pig airway tissues to LTD4. ( Douglas, JS; Duncan, PG, 1985) |
| "75 to 750 pM) of alpha-thrombin prior to contracting in response to higher concentrations during cumulative dose-response experiments." | 1.27 | Thrombin-elicited contractile responses of aortic smooth muscle. ( Aiken, M; Anderson, GF; Ciaglowski, RE; Fenton, JW; Walz, DA, 1985) |
| " On the other hand, in the presence of prostaglandin (PG)-inhibitors the dose-response curve of acetylcholine shifts to the right." | 1.26 | In vitro effect of acetylcholine and bethanechol on the contractions of the human detrusor muscle. Influence of prostaglandins. ( Borda, E; Contreras-Ortiz, N; Gimeno, MF; Gutnisky, R, 1982) |
| "5 Indomethacin treatment reversed the isoprenaline desensitization induced by chronic treatment (0." | 1.26 | Tolerance of guinea-pig airway muscle preparations to relaxant agonists induced by chronic exposure to isoprenaline in vivo. ( Brink, C, 1981) |
| "The indomethacin-induced increase in the amplitude of spontaneous contractions was not affected by intrinsic nerves and was accompanied by an increase in spike discharges on the slow wave and 45Ca uptake in the muscle cells." | 1.26 | Endogenous prostaglandins and spontaneous contractions in the circular muscle of the guinea-pig stomach. ( Ishizawa, M; Nitta, H, 1980) |
| "Indomethacin is an effective inhibitor of prostaglandin synthetase and has recently been demonstrated to inhibit inflammatory fluid secretion into the gallbladder in experimental cholecystitis." | 1.26 | Indomethacin intravenously--a new way for effective relief of biliary pain: a double-blind study in man. ( Jansson, R; Svanvik, J; Thornell, E, 1981) |
| " ETA did not affect the phenylephrine dose-response curves and nor did 8 micrograms/ml of indomethacin, whereas the high dose was inhibitory." | 1.26 | Role of prostaglandins in contractile activity of the ampulla of the rabbit oviduct. ( Coons, LW; Harper, MJ; Hodgson, BJ; Radicke, DA; Valenzuela, G, 1980) |
| " The angiotensin dose-response curves of tachyphylactic organs were shifted to the right, and the maximum responses were depressed in proportion to the conditioning doses of the hormone." | 1.26 | Specific desensitization (tachyphylaxis) of the guinea pig ileum to angiotensin II. ( Mendes, GB; Paiva, AC; Paiva, TB, 1977) |
| " On the rat isolated uterus, angiotensin II and the heptapeptide displayed non-parallel dose-response curves." | 1.26 | A comparison of the effects of angiotensin II and heptapeptide on smooth muscle (vascular and uterine). ( HAll, MM; Khairallah, PA; Moore, AF, 1976) |
| "Indomethacin-treated bovine iris-ciliary body microsomes (IBIM) have been studied for their ability to convert PG endoperoxides into either thromboxane-A2 (TxA2)-like or prostacyclin (PGI2)-like activity." | 1.26 | Microsomal preparations of normal bovine iris-ciliary body generate prostacyclin-like but not thromboxane-A2-activity. ( Eakins, HM; Eakins, KE; Kulkarni, FS; Saber, WL, 1977) |
| "Indoprofen has been studied in vitro as a possible selective inhibitor of thromboxane-synthetase in guinea pig lungs perfused with arachidonic acid." | 1.26 | Effect of indoprofen on prostaglandin and thromboxane A2 synthesis in the guinea pig lung. ( Ceserani, R; Colombo, M; Mandelli, V, 1979) |
| " Oviductal segments removed 2 h after endotoxin (26 h after hCG) showed electrical activity confined to the ampullary-isthmic-junction (AIJ), where ova were located; the dose-response curve for PE was shifted to the right and the maximum contraction was depressed." | 1.26 | Accelerated ovum transport in rabbits induced by endotoxin II. Changes in oviductal smooth muscle activity. ( Harper, MJ; Hodgson, BJ; Valenzuela, G, 1978) |
| "Both indomethacin and ETYA were able to reverse the tachyphylaxis to angiotensin II." | 1.26 | Angiotensin analogs: effect of prostaglandin synthesis inhibitor. ( Gurchinoff, S; Hall, MM; Khairallah, PA; Khosla, MC, 1978) |
| "Indomethacin treatment caused no changes in the spontaneous motility, and this inhibitor of prostaglandins synthesis decreased the responses of epididymis to norepinephrine or acetylcholine." | 1.26 | Effects of prostaglandins and indomethacin on rat epididymal responses to norepinephrine and acetylcholine. ( Hib, J; Oscar, P, 1978) |
| "Adenosine has actions on smooth muscle similar to those of prostaglandin (PG) antagonists." | 1.26 | Adenosine as a natural prostaglandin antagonist in vascular smooth muscle. ( Ally, AI; Horrobin, DF; Karmali, RA; Karmazyn, M; Manku, MS; Morgan, RO, 1977) |
| " The dosage of PGEs required was 1 to 4 mug/kg/min." | 1.26 | Studies on the effects of prostaglandins E1, E2, A1, and A2 on the dustus arteriosus of swine in vivo using cineangiography. ( Elliott, RB; Elliott, RL; Neutze, JM; Starling, MB, 1976) |
| " For higher initial contractions relaxation is slowed during the first minute of wash out, probably because of the sigmoid shape of the dose-response curve." | 1.26 | Relaxation of splenic strips during wash out with amine-free solution after an exposure to noradrenaline. ( Lindmark, E; Schlör, G; Trendelenburg, U, 1976) |
| "Prevention of premature labor is of considerable interest in research and clinics." | 1.25 | The treatment of threatened premature labor by tocolytics, Ca++-Antagonists and anti-inflammatory drugs. ( Mosler, KH, 1975) |
| " Dose-response curves of classical hyperbolic shape are obtained in the first three preparations, but not in the others." | 1.25 | Application of drug receptor theories to the analysis of the myotropic effects of bradykinin. ( Barabe, J; Park, WK; Regoli, D, 1975) |
| " Polyphloretin phosphate at a concentration of 10 mug/ml resulted in complete identity of dioestrus and metoestrus dose-response curves to angiotensin and oxytocin." | 1.25 | Effects of prostaglandin inhibitors on angiotensin, oxytocin and prostaglandin F2 alpha contractile effects on the rat uterus during the oestrous cycle. ( Baudouin-Legros, M; Meyer, P; Worcel, M, 1974) |
| "When treated with indomethacin, the rat stomach strip and chick rectum preparation slowly relaxed, whether they were bathed in Krebs solution or blood." | 1.25 | Prostaglandins, oxygen tension and smooth muscle tone. ( Eckenfels, A; Vane, JR, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 622 (54.13) | 18.7374 |
| 1990's | 350 (30.46) | 18.2507 |
| 2000's | 135 (11.75) | 29.6817 |
| 2010's | 40 (3.48) | 24.3611 |
| 2020's | 2 (0.17) | 2.80 |
| Authors | Studies |
|---|---|
| Bell, MR | 1 |
| D'Ambra, TE | 1 |
| Kumar, V | 1 |
| Eissenstat, MA | 1 |
| Herrmann, JL | 1 |
| Wetzel, JR | 1 |
| Rosi, D | 1 |
| Philion, RE | 1 |
| Daum, SJ | 1 |
| Hlasta, DJ | 1 |
| Narisada, M | 1 |
| Ohtani, M | 1 |
| Watanabe, F | 1 |
| Uchida, K | 2 |
| Arita, H | 1 |
| Doteuchi, M | 1 |
| Hanasaki, K | 1 |
| Kakushi, H | 1 |
| Otani, K | 1 |
| Hara, S | 1 |
| Chung, MI | 1 |
| Gan, KH | 1 |
| Lin, CN | 1 |
| Ko, FN | 1 |
| Teng, CM | 1 |
| Prakash, E | 1 |
| Pavithra, S | 1 |
| Kishor Kumar, DG | 1 |
| Panigrahi, M | 1 |
| Singh, TU | 1 |
| Kumar, D | 1 |
| Parida, S | 1 |
| Butenas, ALE | 1 |
| Hopkins, TD | 1 |
| Rollins, KS | 1 |
| Felice, KP | 1 |
| Copp, SW | 1 |
| Britto-Júnior, J | 1 |
| Jacintho, FF | 1 |
| Figueiredo Murari, GM | 1 |
| Campos, R | 1 |
| Moreno, RA | 1 |
| Antunes, E | 1 |
| Mónica, FZ | 1 |
| De Nucci, G | 2 |
| López, RM | 2 |
| López, JE | 1 |
| López, JS | 1 |
| Castillo, MC | 2 |
| Guevara, G | 1 |
| Morales, JA | 1 |
| López, OA | 1 |
| Lozano, J | 1 |
| Castillo, EF | 3 |
| Esmaeili, H | 1 |
| Sharifi, M | 1 |
| Esmailidehaj, M | 1 |
| Rezvani, ME | 1 |
| Hafizibarjin, Z | 1 |
| Unt, DV | 1 |
| Lobov, GI | 2 |
| Ozen, G | 1 |
| Topal, G | 1 |
| Gomez, I | 1 |
| Ghorreshi, A | 1 |
| Boukais, K | 1 |
| Benyahia, C | 1 |
| Kanyinda, L | 1 |
| Longrois, D | 1 |
| Teskin, O | 1 |
| Uydes-Dogan, BS | 2 |
| Norel, X | 5 |
| Demirci, B | 1 |
| Demir, O | 1 |
| Dost, T | 1 |
| Birincioglu, M | 1 |
| Guarino, MP | 1 |
| Sessa, R | 1 |
| Altomare, A | 1 |
| Cocca, S | 1 |
| Di Pietro, M | 1 |
| Carotti, S | 1 |
| Schiavoni, G | 1 |
| Alloni, R | 1 |
| Emerenziani, S | 1 |
| Morini, S | 1 |
| Severi, C | 1 |
| Cicala, M | 1 |
| Gioda, CR | 1 |
| Capettini, LS | 1 |
| Cruz, JS | 1 |
| Lemos, VS | 2 |
| Mastropaolo, M | 1 |
| Zizzo, MG | 1 |
| Auteri, M | 1 |
| Mulè, F | 1 |
| Serio, R | 1 |
| Terranova, C | 1 |
| Petrella, C | 1 |
| Improta, G | 1 |
| Severini, C | 1 |
| Signore, F | 1 |
| Damiani, P | 1 |
| Plotti, F | 1 |
| Scarpignato, C | 1 |
| Angioli, R | 1 |
| Murrant, CL | 1 |
| Dodd, JD | 1 |
| Foster, AJ | 1 |
| Inch, KA | 1 |
| Muckle, FR | 1 |
| Ruiz, DA | 1 |
| Simpson, JA | 1 |
| Scholl, JH | 1 |
| Ianchuk, PI | 1 |
| Vynohradova, OO | 1 |
| Pasichnichenko, OM | 1 |
| Kostenko, SS | 1 |
| Yuan, WS | 1 |
| Xu, LJ | 1 |
| Liu, MD | 1 |
| Wang, YB | 1 |
| Li, D | 1 |
| Fornai, M | 1 |
| Colucci, R | 1 |
| Antonioli, L | 1 |
| Ippolito, C | 1 |
| Segnani, C | 1 |
| Buccianti, P | 1 |
| Marioni, A | 1 |
| Chiarugi, M | 1 |
| Villanacci, V | 1 |
| Bassotti, G | 1 |
| Blandizzi, C | 1 |
| Bernardini, N | 1 |
| Saidullah, B | 1 |
| Muralidhar, K | 1 |
| Fahim, M | 2 |
| Lichtenberger, LM | 1 |
| Bhattarai, D | 1 |
| Phan, TM | 1 |
| Dial, EJ | 1 |
| Uray, K | 1 |
| Shirole, RL | 1 |
| Shirole, NL | 1 |
| Saraf, MN | 1 |
| Vladimirova, IA | 1 |
| Philyppov, IB | 1 |
| Kulieva, EM | 1 |
| Paduraru, ON | 1 |
| Shuba, YY | 1 |
| Shuba, YM | 1 |
| Vasconcelos, TB | 1 |
| Ribeiro-Filho, HV | 1 |
| Lucetti, LT | 1 |
| Magalhães, PJ | 2 |
| Chiba, Y | 2 |
| Sato, S | 1 |
| Misawa, M | 2 |
| Badawi, JK | 1 |
| Seja, T | 1 |
| Bross, S | 1 |
| de Godoy, MA | 1 |
| Rattan, N | 1 |
| Rattan, S | 4 |
| Fitzgibbon, J | 1 |
| Morrison, JJ | 1 |
| Smith, TJ | 1 |
| O'Brien, M | 1 |
| Occhiuto, F | 1 |
| Pino, A | 1 |
| Palumbo, DR | 1 |
| Samperi, S | 1 |
| De Pasquale, R | 1 |
| Sturlese, E | 1 |
| Circosta, C | 1 |
| Brizic, I | 1 |
| Modun, D | 1 |
| Vukovic, J | 1 |
| Budimir, D | 1 |
| Katalinic, V | 1 |
| Boban, M | 1 |
| Fernández-Ferreiro, A | 1 |
| Gil-Longo, J | 1 |
| Collins, C | 1 |
| Klausner, AP | 1 |
| Herrick, B | 1 |
| Koo, HP | 1 |
| Miner, AS | 1 |
| Henderson, SC | 1 |
| Ratz, PH | 1 |
| Toyoshima, K | 1 |
| Momma, K | 2 |
| Nakanishi, T | 2 |
| Han, JH | 2 |
| Lee, MY | 3 |
| Myung, SC | 3 |
| Amburgey, OA | 1 |
| Reeves, SA | 1 |
| Bernstein, IM | 1 |
| Cipolla, MJ | 1 |
| Castillo-Hernandez, MC | 1 |
| Guevara-Balcazar, G | 1 |
| Lopez-Sanchez, P | 1 |
| Asbun-Bojalil, J | 1 |
| Castillo-Henkel, C | 1 |
| Stanisçuaski, F | 1 |
| Te Brugge, V | 1 |
| Carlini, CR | 1 |
| Orchard, I | 1 |
| Lee, SY | 1 |
| Chang, IH | 1 |
| Kim, HJ | 1 |
| Kim, W | 1 |
| Kaithwas, G | 1 |
| Majumdar, DK | 1 |
| Wong, ES | 1 |
| Man, RY | 1 |
| Vanhoutte, PM | 16 |
| Ng, KF | 1 |
| Flores-Soto, E | 1 |
| Carbajal, V | 1 |
| Reyes-García, J | 1 |
| García-Hernández, LM | 1 |
| Figueroa, A | 1 |
| Checa, M | 1 |
| Barajas-López, C | 1 |
| Montaño, LM | 1 |
| Shimizu, N | 1 |
| Nakahara, T | 4 |
| Kubota, Y | 3 |
| Sakamoto, K | 4 |
| Ishii, K | 5 |
| Lima, FC | 1 |
| Peixoto-Neves, D | 1 |
| Gomes, MD | 1 |
| Coelho-de-Souza, AN | 1 |
| Lima, CC | 1 |
| Araújo Zin, W | 1 |
| Saad, L | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Late Phase Administration Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation[NCT03513458] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2020-09-30 | Withdrawn (stopped due to [The risk of inhaled allergen challenge and anakinra treatment outweigh benefits to participants with allergic asthma due to the COVID-19 pandemic.) | ||
| Early Phase Administration of Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation[NCT03513471] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2019-08-09 | Withdrawn (stopped due to The risk of inhaled allergen challenge and anakinra treatment outweigh benefits to participants with allergic asthma due to the COVID-19 pandemic.) | ||
| Effect of Acupuncture on Vascular Biomarkers and Psychological Well-Being of Women Undergoing In Vitro Fertilization (IVF)[NCT02591186] | 60 participants (Actual) | Interventional | 2015-11-01 | Completed | |||
| Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253] | Phase 3 | 44 participants (Anticipated) | Interventional | 2016-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for indomethacin and Muscle Contraction
| Article | Year |
|---|---|
Ontogeny of the ductus arteriosus response to prostaglandins and inhibitors of their synthesis.
Topics: Animals; Arachidonic Acids; Ductus Arteriosus; Epoprostenol; Female; Fetus; Gestational Age; Humans; | 1980 |
Tyrosine kinase pathways and the regulation of smooth muscle contractility.
Topics: Angiotensin II; Animals; Epidermal Growth Factor; Humans; Indomethacin; Muscle Contraction; Muscle, | 1994 |
Eicosanoids and ovulation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Eicosanoids; Female; Gonadotropins, Pituitary; Hum | 1993 |
Indomethacin--a calcium antagonist.
Topics: Animals; Blood Vessels; Calcium; Endothelium; Glucuronidase; Granulocytes; In Vitro Techniques; Indo | 1977 |
Inhibitors of prostaglandin, prostacyclin, and thromboxane synthesis.
Topics: Animals; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Epoprostenol; Female; Humans; Indome | 1978 |
Vascular smooth muscle and prostaglandins.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Aorta; Aspirin; Epinephrine; Indomethacin; | 1976 |
Prejunctional control of excitatory neuroeffector transmission by prostaglandins in the airway smooth muscle tissue.
Topics: Acetylcholine; Animals; Bronchi; Bronchoconstriction; Dogs; Humans; Indomethacin; Muscle Contraction | 1991 |
Vascular actions of leukotrienes.
Topics: Aminophylline; Animals; Atropine; Blood Platelets; Blood Vessels; Capillary Permeability; Cimetidine | 1985 |
Pharmacology of angiotensin.
Topics: Acetylcholine; Adrenal Glands; Adrenal Medulla; Angiotensin II; Animals; Blood Pressure; Cats; Centr | 1974 |
3 trials available for indomethacin and Muscle Contraction
| Article | Year |
|---|---|
Prostaglandin synthesis can be inhibited locally by infusion of NSAIDS through microdialysis catheters in human skeletal muscle.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Catheters, Indwelling; Cyclooxygenase Inhibitors; Di | 2008 |
Cyclooxygenase products sensitize muscle mechanoreceptors in humans with heart failure.
Topics: Adenosine; Adult; Aminophylline; Blood Pressure; Cyclooxygenase Inhibitors; Double-Blind Method; Fem | 2008 |
Benorylate and indomethacin in the treatment of rheumatoid disease: a double-blind clinical trial.
Topics: Acetamides; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Benz | 1972 |
1137 other studies available for indomethacin and Muscle Contraction
| Article | Year |
|---|---|
Antinociceptive (aminoalkyl)indoles.
Topics: Analgesia; Analgesics; Animals; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Indoles; M | 1991 |
Synthesis and in vitro activity of various derivatives of a novel thromboxane receptor antagonist, (+/-)-(5Z)-7-[3-endo-[(phenylsulfonyl)amino]bicyclo[2.2.1] hept-2-exo-yl]heptenoic acid.
Topics: Animals; Aorta; Blood Platelets; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Chemical Phenome | 1988 |
Antiplatelet effects and vasorelaxing action of some constituents of Formosan plants.
Topics: Animals; Anthraquinones; Aorta, Thoracic; Female; In Vitro Techniques; Male; Muscle Contraction; Mus | 1993 |
TXA2 mediates LPA1-stimulated uterine contraction in late pregnant mouse.
Topics: Animals; Female; Indomethacin; Lysophospholipids; Mice; Muscle Contraction; Pregnancy; Receptors, Ly | 2023 |
Investigation of the mechanisms of cyclooxygenase-mediated mechanoreflex sensitization in a rat model of simulated peripheral artery disease.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Femoral Artery; Ganglia, S | 2019 |
Electrical field stimulation induces endothelium-dependent contraction of human umbilical cord vessels.
Topics: Adult; Atropine; Blood Vessels; Electric Stimulation; Glyburide; Humans; Indomethacin; Muscle Contra | 2020 |
Effects of indomethacin on prostanoid synthesis and vasomotor responsiveness in endothelium-denuded abdominal and thoracic aortas of Wistar rats.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Biosynthetic Pathways; Cyclooxygenase 1; | 2017 |
Vasodilatory effect of asafoetida essential oil on rat aorta rings: The role of nitric oxide, prostacyclin, and calcium channels.
Topics: Animals; Aorta, Thoracic; Calcium Channels; Endothelium, Vascular; Epoprostenol; Ferula; Indomethaci | 2017 |
Inhibitory Effect of Interferons on Contractive Activity of Bovine Mesenteric Lymphatic Vessels and Nodes.
Topics: Animals; Apamin; Cattle; Charybdotoxin; Dose-Response Relationship, Drug; Endothelial Cells; Epopros | 2017 |
Control of human vascular tone by prostanoids derived from perivascular adipose tissue.
Topics: Adipose Tissue, White; Aged; Dinoprostone; Epoprostenol; Female; Humans; Indomethacin; Inhibitory Co | 2013 |
Antioxidative effect of aspirin on vascular function of aged ovariectomized rats.
Topics: Acetylcholine; Age Factors; Animals; Antioxidants; Aorta; Aspirin; Endothelium, Vascular; Female; In | 2014 |
Human colonic myogenic dysfunction induced by mucosal lipopolysaccharide translocation and oxidative stress.
Topics: Aged; Catalase; Colon; Humans; Hydrogen Peroxide; Indomethacin; Intestinal Mucosa; Lipopolysaccharid | 2013 |
Thiamine deficiency leads to reduced nitric oxide production and vascular dysfunction in rats.
Topics: Acetylcholine; Animals; Aorta; Hydrazines; Indomethacin; Male; Muscle Contraction; NG-Nitroarginine | 2014 |
Arginine vasopressin, via activation of post-junctional V1 receptors, induces contractile effects in mouse distal colon.
Topics: Animals; Arginine Vasopressin; Atropine; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; | 2013 |
Relaxant effect of proton pump inhibitors on in vitro myometrium from pregnant women.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Apamin; Calcium; Dinoprostone; Esomeprazole; Female; Humans | 2014 |
Prostaglandins induce vasodilatation of the microvasculature during muscle contraction and induce vasodilatation independent of adenosine.
Topics: Adenosine; Animals; Arterioles; Cricetinae; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Indomethac | 2014 |
[Participation of eicosanoids in the mechanisms of contractile reactions of the portal vein to adrenaline and noradrenaline].
Topics: Animals; Eicosanoids; Endothelium, Vascular; Epinephrine; Indomethacin; Muscle Contraction; Muscle, | 2013 |
[The different contraction between rat gastric longitudinal and circular smooth muscle induced by extracellular nucleotides].
Topics: Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Indomethacin; Muscle Contraction; Muscle, | 2014 |
Role of cyclooxygenase isoforms in the altered excitatory motor pathways of human colon with diverticular disease.
Topics: Adult; Aged; Aged, 80 and over; Colon; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors | 2014 |
Onset of diabetes modulates the airway smooth muscle reactivity of guinea pigs: role of epithelial mediators.
Topics: Acetylcholine; Animals; Bronchi; Bronchoconstriction; Cyclooxygenase Inhibitors; Diabetes Mellitus, | 2014 |
Suppression of contractile activity in the small intestine by indomethacin and omeprazole.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Enteritis; Gastrointestinal Hemorrhage | 2015 |
In vitro relaxant and spasmolytic effects of essential oil of Pistacia integerrima Stewart ex Brandis Galls.
Topics: Acetylcholine; Animals; Calcium Channels; Calcium Chloride; Epinephrine; Guinea Pigs; Hexamethonium; | 2015 |
[Impact of diabetic complications on neuromuscular transmission in the smooth muscle of the bladder of rats with experimental diabetes].
Topics: Animals; Atropine; Cyclooxygenase 1; Cyclooxygenase 2; Cyclophosphamide; Cystitis; Diabetes Mellitus | 2015 |
β-Citronellol, an alcoholic monoterpene with inhibitory properties on the contractility of rat trachea.
Topics: Acyclic Monoterpenes; Analysis of Variance; Animals; Calcium Channel Blockers; Enzyme Inhibitors; In | 2016 |
Inhibition of antigen-induced bronchial smooth muscle hyperresponsiveness by lovastatin in mice.
Topics: Acetylcholine; Animals; Antigens; Asthma; Atropine; Bronchial Hyperreactivity; Bronchodilator Agents | 2008 |
In vitro effects of the cyclooxygenase inhibitor indomethacin and of the phospholipase-C inhibitor U-73122 on carbachol-induced contractions of porcine detrusor muscle.
Topics: Animals; Carbachol; Cholinergic Agonists; Cyclooxygenase Inhibitors; Dose-Response Relationship, Dru | 2008 |
COX-1 vs. COX-2 as a determinant of basal tone in the internal anal sphincter.
Topics: Anal Canal; Animals; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibit | 2009 |
Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin.
Topics: Amides; Cell Culture Techniques; Cell Line; Collagen; Female; Humans; Indomethacin; Muscle Contracti | 2009 |
Relaxing effects of Valeriana officinalis extracts on isolated human non-pregnant uterine muscle.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Atenolol; Chromatography, High Pressure Liquid; | 2009 |
Differences in vasodilatory response to red wine in rat and guinea pig aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Clotrimazole; Dose-Response Relationship, Drug; Endothelium | 2009 |
Vascular pro-oxidant effects related to the autoxidation of dopamine.
Topics: Animals; Aorta, Thoracic; Catalase; Dopamine; Female; Humans; Hydrogen Peroxide; In Vitro Techniques | 2009 |
Potential for control of detrusor smooth muscle spontaneous rhythmic contraction by cyclooxygenase products released by interstitial cells of Cajal.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Hydrazines; Ibuprofe | 2009 |
Fetal reversed constrictive effect of indomethacin and postnatal delayed closure of the ductus arteriosus following administration of transplacental magnesium sulfate in rats.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drug Ant | 2009 |
The effect of endothelin-1 on the production of interleukin-6 in cultured human detrusor smooth muscle cells, and the effect of interleukin-6 on the contractile response of bladder smooth muscle strips from rats.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cyclooxygenase Inhibitors; Cystit | 2009 |
Resistance artery adaptation to pregnancy counteracts the vasoconstricting influence of plasma from normal pregnant women.
Topics: Adaptation, Physiological; Adult; Analysis of Variance; Angiography; Animals; Blood Pressure; Blood | 2010 |
The influence of constitutive COX-2 in smooth muscle tissue on the contractile effect of phenylephrine in the rat abdominal aorta.
Topics: Animals; Aorta, Abdominal; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibit | 2010 |
Jack bean urease alters serotonin-induced effects on Rhodnius prolixus anterior midgut.
Topics: Analysis of Variance; Animals; Canavalia; Cyclic AMP; Cyclooxygenase Inhibitors; Dose-Response Relat | 2010 |
Effect of low concentrations of hydrogen peroxide on the contractile responses of rat detrusor smooth muscle strips.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2010 |
Evaluation of antiulcer and antisecretory potential of Linum usitatissimum fixed oil and possible mechanism of action.
Topics: Acetylcholine; Animals; Aspirin; Atropine; Cholinergic Antagonists; Cimetidine; Ethanol; Flax; Gastr | 2010 |
Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Anta | 2010 |
In airways ATP refills sarcoplasmic reticulum via P2X smooth muscle receptors and induces contraction through P2Y epithelial receptors.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Guinea Pigs; Indomethacin; Male; Muscle | 2011 |
Contribution of cyclooxygenase-dependent mechanisms to contractile responses to donepezil in the rat urinary bladder.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Donepezil; Indans; Indomethacin; Male; Muscle Contract | 2010 |
Antispasmodic effects of eugenol on rat airway smooth muscle.
Topics: Acetates; Animals; Calcium; Calcium Channels; Cyclopropanes; Dose-Response Relationship, Drug; Elect | 2011 |
The investigation into indomethacin-induced potentiation of the contractile response to antigen in ovalbumin-sensitized guinea-pig tracheas.
Topics: Animals; Antigens; Arachidonic Acid; Drug Synergism; Guinea Pigs; Indomethacin; Lipoxygenase; Male; | 2012 |
Urothelium-dependent and urothelium-independent detrusor contractility mediated by nitric oxide synthase and cyclooxygenase inhibition.
Topics: Analysis of Variance; Animals; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Indomethacin; M | 2011 |
Balloon catheter injury abolishes phenylephrine-induced relaxation in the rat contralateral carotid.
Topics: Angioplasty, Balloon, Coronary; Animals; Carotid Arteries; Carotid Artery Injuries; Cyclic N-Oxides; | 2011 |
Resveratrol prevents bradykinin-induced contraction of rat urinary bladders by decreasing prostaglandin production and calcium influx.
Topics: Animals; Bradykinin; Calcium; Calcium Channel Agonists; Cyclooxygenase Inhibitors; Diltiazem; Dinopr | 2011 |
Influence of influenza A infection on capsaicin-induced responses in murine airways.
Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhi | 2012 |
The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH.
Topics: Bronchi; Cell Culture Techniques; Cells, Cultured; Cyclic AMP; Cyclooxygenase Inhibitors; Dose-Respo | 2012 |
Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation.
Topics: Analysis of Variance; Animals; Arachidonic Acids; Arterioles; Benzamides; Benzoxazines; Blood Pressu | 2012 |
Oxidative stress and successful antioxidant treatment in models of RYR1-related myopathy.
Topics: Acetophenones; Acetylcysteine; Animals; Animals, Genetically Modified; Antioxidants; Behavior, Anima | 2012 |
In vivo and in vitro cardiovascular effects of Papuan taipan (Oxyuranus scutellatus) venom: Exploring "sudden collapse".
Topics: Animals; Australasia; Cardiovascular Agents; Cardiovascular System; Elapid Venoms; Hypotension; In V | 2012 |
The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea.
Topics: Albuterol; Animals; Bronchodilator Agents; Carbachol; Charybdotoxin; Chloroquine; Cholinergic Agonis | 2012 |
The contractile effect of anandamide in the guinea-pig small intestine is mediated by prostanoids but not TRPV1 receptors or capsaicin-sensitive nerves.
Topics: Animals; Arachidonic Acids; Calcium Channel Blockers; Capsaicin; Cyclooxygenase Inhibitors; Endocann | 2013 |
The effect of indomethacin on the muscarinic induced contractions in the isolated normal guinea pig urinary bladder.
Topics: Animals; Arecoline; Cyclooxygenase Inhibitors; Dinoprostone; Guinea Pigs; Indomethacin; Male; Muscar | 2013 |
Effect of indomethacin on the development of eccentric exercise-induced localized sensitive region in the fascia of the rabbit.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Electromyography; Fascia; Fasciitis; Indomethacin; | 2002 |
Vitamin K(1) prevents the effect of hypoxia on phenylephrine-induced contraction in the carotid artery.
Topics: Animals; Carotid Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypoxia; In Vitr | 2002 |
Hypertension alters the participation of contractile prostanoids and superoxide anions in lipopolysaccharide effects on small mesenteric arteries.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 2; Dexamethasone; Dose-Response Rel | 2002 |
Alterations of intestinal motor responsiveness in a model of mild mesenteric ischemia/reperfusion in rats.
Topics: Acetylcholine; Animals; Chymotrypsin; Disease Models, Animal; Dose-Response Relationship, Drug; Elec | 2002 |
Effects of catechins on vascular tone in rat thoracic aorta with endothelium.
Topics: Animals; Aorta, Thoracic; Catechin; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, V | 2002 |
Omeprazole-induced relaxation in rat aorta is partly dependent on endothelium.
Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; In Vitr | 2002 |
In vitro investigation of the effects of cyclooxygenase-2 inhibitors on contractile activity of the equine dorsal and ventral colon.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Colon; Cyclooxygenase 2; Cyclooxygenase | 2002 |
Effect of lipopolysaccharide on rabbit small intestine muscle contractility in vitro: role of prostaglandins.
Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Dinoprostone; Gastrointestinal Motility; Indometh | 2002 |
Study of the mechanisms involved in the bradykinin-induced contraction of the pig iris sphincter muscle in vitro.
Topics: Animals; Atropine; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Dose-Resp | 2003 |
Contractile responses of the human umbilical artery to KCl and serotonin in Ca-free medium and the effects of levcromakalim.
Topics: Calcium; Chelating Agents; Cromakalim; Egtazic Acid; Enzyme Inhibitors; Humans; Indomethacin; Muscle | 2003 |
A thromboxane A(2) system in the Atlantic stingray, Dasyatis sabina.
Topics: Animals; Aorta; Cyclooxygenase Inhibitors; Elasmobranchii; Female; In Vitro Techniques; Indomethacin | 2003 |
Protease-activated receptor-2-mediated contraction in the rat urinary bladder: the role of urinary bladder mucosa.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Indomethacin; Mal | 2003 |
Differential effects of 5,6-EET on segmental pulmonary vasoactivity in the rabbit.
Topics: 6-Ketoprostaglandin F1 alpha; 8,11,14-Eicosatrienoic Acid; Animals; Cyclooxygenase Inhibitors; Epopr | 2003 |
Mechanisms involved in the loss of excitatory post-stimulus responses by inflammation.
Topics: Adenosine Triphosphate; Animals; Colitis; Cyclooxygenase Inhibitors; Electric Stimulation; Female; I | 2003 |
The contraction of the human pulmonary artery by LTC4 is resistant to cysLT1 antagonists and counteracted by prostacyclin release.
Topics: Adult; Aged; Cysteine; Humans; Indomethacin; Kinetics; Leukotriene C4; Leukotrienes; Lung Neoplasms; | 2002 |
Action of progesterone on contractile activity of isolated gastric strips in rats.
Topics: Animals; Gastrointestinal Motility; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, S | 2003 |
Effect of vigabatrin on contractile response to arachidonic acid and prostaglandins in smooth muscle preparations and platelet aggregation in experimental laboratory animals.
Topics: 4-Aminobutyrate Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Arachidonic A | 2003 |
Influence of cholecystitis state on pharmacological response to cholecystokinin of isolated human gallbladder with gallstones.
Topics: Acetylcholine; Adult; Atropine; Cholecystectomy; Cholecystitis; Cholecystokinin; Cholelithiasis; Dru | 2003 |
Effect of indomethacin on force responses and sarcoplasmic reticulum function in skinned skeletal muscle fibers and cytosolic [Ca2+] in myotubes.
Topics: Animals; Calcium; Cytosol; Electrophysiology; Enzyme Inhibitors; Female; Histological Techniques; In | 2003 |
Involvement of cholinoceptors in cadmium-induced endothelial dysfunction.
Topics: Acetylcholine; Administration, Oral; Animals; Aorta, Thoracic; Atropine; Cadmium; Calcimycin; Dose-R | 2003 |
Myogenic responses of isolated adipose tissue arterioles.
Topics: Adipose Tissue; Animals; Arterioles; Blood Pressure; Calcium; Cyclooxygenase Inhibitors; Indomethaci | 2003 |
Pharmacological characterization of pre- and postsynaptic prostanoid receptors in pig gastric fundus.
Topics: Animals; Choline; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Dr | 2003 |
Mechanisms of vasorelaxation to 17beta-oestradiol in rat arteries.
Topics: Animals; Aorta, Thoracic; Calcium; Charybdotoxin; Cyclooxygenase Inhibitors; Endothelium, Vascular; | 2003 |
PDE4D plays a critical role in the control of airway smooth muscle contraction.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arginine Vasopressin; Bronchoconstrictor Agents; Carba | 2003 |
Role of prostaglandins in lipopolysaccharide effects on K+-induced contractions in rabbit small intestine.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprostone; Duodenum; Ileum; Indomethacin; Injections, Intrave | 2003 |
Effects of flavonoids on vascular smooth muscle of the isolated rat thoracic aorta.
Topics: Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Flavonoids; In Vitro Techniq | 2003 |
Intraluminal pressure oscillation enhances subsequent airway contraction in isolated bronchial segments.
Topics: Animals; Biological Clocks; Bronchoconstriction; In Vitro Techniques; Indomethacin; Lung; Muscle Con | 2004 |
Protease-activated receptor-2-mediated contraction of urinary bladder is enhanced in cyclophosphamide-treated rats.
Topics: Animals; Cyclooxygenase 2; Cyclophosphamide; Cystitis; Dinoprostone; In Vitro Techniques; Indomethac | 2004 |
Chronic methionine load-induced hyperhomocysteinemia enhances rat carotid responsiveness for angiotensin II.
Topics: Angiotensin II; Animals; Carotid Arteries; Cyclooxygenase Inhibitors; Dose-Response Relationship, Dr | 2004 |
Myogenic tone and reactivity of the rat ophthalmic artery.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Homeostasis; Indomethacin; Male; Muscl | 2004 |
EP4 prostanoid receptor-mediated vasodilatation of human middle cerebral arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Aged, 80 and over; Bipheny | 2004 |
In vitro investigation of the effects of nonsteroidal anti-inflammatory drugs, prostaglandin E2, and prostaglandin F2alpha on contractile activity of the third compartment of the stomach of llamas.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Camelids, New World; Dinoprost; Dinopro | 2004 |
Effects of alpha calcitonin gene-related peptide in human bronchial smooth muscle and pulmonary artery.
Topics: Acetylcholine; Bronchi; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Endotheli | 2004 |
Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Factors; Chlorides; Diabetes Mellitus, Experimen | 2004 |
Prostanoids contribute to the oxygen-dependent regulation of vascular tone of human umbilical vein.
Topics: Endothelium, Vascular; Female; Humans; Indomethacin; Membrane Potentials; Muscle Contraction; Muscle | 2004 |
The effect of the indomethacin on phosphodiesterase inhibitors mediated responses in isolated trachea preparations.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Guinea Pigs; Histamine; In Vitro Techniques; Indom | 2004 |
Mechanisms underlying the effect of E. coli endotoxin on contractile function of lymphatic vessels.
Topics: Animals; Cattle; Endotoxins; Epoprostenol; In Vitro Techniques; Indomethacin; Lymphatic Vessels; Mus | 2004 |
[Anti-cholinergic effect of Pluchea ovalis (pers.) Dc. (asteraceae) root extract on isolated Wistar rat tracheae].
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asteraceae; Bronchoconstriction; Ch | 2004 |
BK2 but not BK1 receptors mediating contractile response in human umbilical arteries: role of thromboxane A2.
Topics: Bradykinin; Bradykinin B1 Receptor Antagonists; Bradykinin B2 Receptor Antagonists; Dose-Response Re | 2004 |
Effects of NSAIDs on bladder function in normal and cystitis rats: a comparison study of aspirin, indomethacin, and ketoprofen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclophosphamide; Cystitis; Female; Gastr | 2004 |
Aggravation of inflammatory bowel disease by cyclooxygenase-2 inhibitors in rats.
Topics: Animals; Celecoxib; Colon; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; | 2004 |
An indomethacin-sensitive contraction induced by beta-antagonists in guinea pig airways.
Topics: Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techni | 2004 |
Relaxation induced by acetylcholine involves endothelium-derived hyperpolarizing factor in 2-kidney 1-clip hypertensive rat carotid arteries.
Topics: Acetylcholine; Animals; Biological Factors; Carotid Arteries; Cyclic GMP; Cyclooxygenase Inhibitors; | 2004 |
Regulation of VEGF and bFGF mRNA expression and other proliferative compounds in skeletal muscle cells.
Topics: Adenosine; Adenosine Diphosphate; Animals; Cell Proliferation; Cells, Cultured; Electric Stimulation | 2004 |
Involvement of cyclooxygenase-dependent pathway in contraction of isolated ileum by urotensin II.
Topics: Anesthetics, Local; Animals; Atropine; Calcium Channel Blockers; Cyclooxygenase 1; Cyclooxygenase 2; | 2005 |
Higher viscosity participates in the regulation of coronary flow via nitric oxide and indomethacin-sensitive contracting factor.
Topics: Animals; Blood Viscosity; Coronary Circulation; Cyclooxygenase Inhibitors; Dextrans; Enzyme Inhibito | 2004 |
Celecoxib inhibits ureteral contractility and prostanoid release.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Celecoxib; Cyclooxygenase Inhibitors; Depression, Chemical; D | 2005 |
K(+)-induced vasodilation in the rat kidney is dependent on the endothelium and activation of K+ channels.
Topics: Animals; Barium Compounds; Bradykinin; Carbenoxolone; Chlorides; Clotrimazole; Cytochrome P-450 Enzy | 2005 |
Effect of anti-inflammatory and antioxidant drugs on the long-term repair of severely injured mouse skeletal muscle.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blotting, Western; Curcumin; Cyclooxygenase Inhibit | 2005 |
Indomethacin-induced ileitis is associated with tensiometric, vascular and oxidative changes in the experimental rat model.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Carbachol; Cholinergic Agonists; Disease Models, | 2005 |
The impact of respiratory syncytial virus infection on endothelin receptor function and release in sheep bronchial explants.
Topics: Animals; Bronchi; Culture Media, Conditioned; Dexamethasone; Dinoprostone; Dose-Response Relationshi | 2004 |
Shortening increases spontaneous contractility in myometrium from pregnant women at term.
Topics: Analysis of Variance; Cesarean Section; Female; Humans; Indomethacin; Muscle Contraction; Myometrium | 2005 |
Endothelin-1-induced translocation of RhoA is mediated by endothelin ET(A) receptors in rat bronchial smooth muscle.
Topics: Amides; Animals; Atropine; Blotting, Western; Bronchi; Cell Membrane; Cytosol; Dose-Response Relatio | 2005 |
Relaxant effect of adrenomedullin on bovine isolated iris sphincter muscle under resting conditions.
Topics: Adrenomedullin; Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor A | 2005 |
Effect of indomethacin on electrical field stimulation-induced contractions of isolated transverse and longitudinal rat gastric fundus strips.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Electric Stimulation; Gastric Fundus; In Vitro Tec | 2005 |
Isoquercitrin from Argemone platyceras inhibits carbachol and leukotriene D4-induced contraction in guinea-pig airways.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Argemone; Asthma; | 2005 |
Nitric oxide-dependent vasorelaxation induced by extractive solutions and fractions of Maytenus ilicifolia Mart ex Reissek (Celastraceae) leaves.
Topics: Animals; Aorta; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; | 2006 |
Cyclooxygenase blockade attenuates responses of group III and IV muscle afferents to dynamic exercise in cats.
Topics: Animals; Arachidonic Acid; Cats; Cyclooxygenase Inhibitors; Electromyography; Hindlimb; Indomethacin | 2006 |
Hypoxia promotes relaxation of bovine coronary arteries through lowering cytosolic NADPH.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Calcium Signaling | 2006 |
Epithelium-dependent and -independent inhibitory effects of sivelestat, a neutrophil elastase inhibitor, on substance P-induced contraction of airway smooth muscle in lipopolysaccharide-treated guinea-pigs.
Topics: Animals; Bronchi; Glycine; Guinea Pigs; In Vitro Techniques; Indomethacin; Leukocyte Elastase; Lipop | 2005 |
Endothelium-dependent inhibition of the contractile response is decreased in aorta from aged and spontaneously hypertensive rats.
Topics: Aging; Animals; Aorta; Disease Models, Animal; Endothelium; Hypertension; Indomethacin; Male; Muscle | 2006 |
Vasomotor action of insulin on the rabbit normal cavernous smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2006 |
B(2)-receptor modulation of the reactivity to phenylephrine and angiotensin II in the carotid artery of normotensive rats after trandolapril treatment.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Carotid Arteries; End | 2006 |
Altered neurogenic and mechanical responses to acetylcholine, ATP and substance P in detrusor from rat with outlet obstruction.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Cholinergic Agonists; Cyclooxygenase Inhib | 2006 |
The role of tyrosine kinase in prostaglandin E2 and vanadate-evoked contractions in rabbit duodenum in vitro.
Topics: Animals; Calcium; Carbachol; Dinoprostone; Dose-Response Relationship, Drug; Duodenum; Estrenes; Gen | 2006 |
Plasma levels of nitrites, PGF1alpha, and nitrotyrosine in LPS-treated rats: functional and histochemical implications in aorta.
Topics: Animals; Aorta; Enzyme Inhibitors; Indomethacin; Lipopolysaccharides; Male; Muscle Contraction; Musc | 2006 |
Effect of sodium orthovanadate on the urinary bladder rings isolated from normal and hyperglycemic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Dose-Response Relationship, Drug; En | 2006 |
Roles of stretch-activated cation channel and Rho-kinase in the spontaneous contraction of airway smooth muscle.
Topics: Amides; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cations; Cyclooxygenas | 2006 |
Mechanisms underlying ATP-induced endothelium-dependent contractions in the SHR aorta.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Cytochro | 2007 |
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Acetylcholine; Albuter | 2006 |
Altered arachidonic acid-mediated responses in the perfused kidney of the streptozotocin-induced diabetic rat.
Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Diabetes M | 2006 |
Enhancement effects of nicotine on neurogenic contractile responses in rabbit gastric fundus.
Topics: Animals; Cadmium; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Electric Stimulation; | 2007 |
Effects of washout following indomethacin administration on electrical field stimulation-induced isolated rat gastric fundus strip contractions.
Topics: Animals; Electric Stimulation; Gastric Fundus; In Vitro Techniques; Indomethacin; Male; Muscle Contr | 2007 |
Effects of anethole and structural analogues on the contractility of rat isolated aorta: Involvement of voltage-dependent Ca2+-channels.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Aorta; Calcium; Calcium Channels; Cardiovascular Agents | 2007 |
Tachykinin NK2 receptor and functional mechanisms in human colon: changes with indomethacin and in diverticular disease and ulcerative colitis.
Topics: Adult; Aged; Aged, 80 and over; Colitis, Ulcerative; Colon; Diverticulum, Colon; Female; Humans; In | 2008 |
Phagocytotic activation of muscularis resident macrophages inhibits smooth muscle contraction in rat ileum.
Topics: Animals; Carbachol; Cyclooxygenase 2; Dextrans; Enzyme Induction; Female; Ileum; Indomethacin; Macro | 2007 |
Alterations in spontaneous contractions of rat ileum and jejunum after peritonitis.
Topics: Animals; Celecoxib; Guanidines; Ileum; In Vitro Techniques; Indomethacin; Jejunum; Male; Muscle Cont | 2008 |
Endothelial nitric oxide has inhibitory effects on rhythmic contractions in the aortas of sinoaortic deafferented rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Autonomic Denervation; Blood Pressure; Dose-Respo | 2007 |
Functional vasodilation in the rat spinotrapezius muscle: role of nitric oxide, prostanoids and epoxyeicosatrienoic acids.
Topics: Animals; Caproates; Eicosanoids; Indomethacin; Male; Muscle Contraction; Muscle, Skeletal; NG-Nitroa | 2008 |
Ketorolac effectively inhibits ureteral contractility in vitro.
Topics: Animals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; In Vitro Techniques; Indometha | 2008 |
20-HETE increases renal sympathetic nerve activity via activation of chemically and mechanically sensitive muscle afferents.
Topics: Adrenergic Fibers; Animals; Hydroxyeicosatetraenoic Acids; Indomethacin; Kidney; Male; Muscle Contra | 2008 |
Control of neurotransmission by prostaglandins in canine trachealis smooth muscle.
Topics: Animals; Dinoprostone; Dogs; Drug Interactions; Electric Stimulation; Electrophysiology; Indomethaci | 1984 |
O2-sensitivity of beta adrenergic responsiveness in isolated bovine and porcine coronary arteries.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Coronary Vessels; Dose-Response Relationship, | 1984 |
Possible involvement of a product of the 5-lipoxygenase pathway in mediation of indomethacin-induced inhibition of cholinergic transmission in guinea-pig ileum.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Chromones; Dinoprostone; Electric Stimu | 1984 |
Effects of thyrotropin-releasing hormone (TRH) on the isolated small intestine and taenia coli of the guinea pig.
Topics: Animals; Dose-Response Relationship, Drug; Guanethidine; Guinea Pigs; Hexamethonium Compounds; In Vi | 1980 |
Gastrointestinal actions of carbacyclin, a stable mimic of prostacyclin.
Topics: Animals; Digestive System; Epoprostenol; Gastric Acid; Gastric Mucosa; In Vitro Techniques; Indometh | 1980 |
Relationship between spasmogenic activity of bombesin and prostaglandins on the rat pylorus.
Topics: Animals; Aspirin; Bombesin; Female; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, S | 1980 |
Antagonism of prostanoid-induced contractions of rat gastric fundus muscle by SC-19220, sodium meclofenamate, indomethacin or trimethoquinol.
Topics: Acetylcholine; Animals; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydraz | 1980 |
The effects of SRS-A and histamine antagonists on antigen-induced contraction of guinea pig trachea.
Topics: Airway Resistance; Animals; Antigens; Atropine; Autacoids; Chromones; Drug Interactions; Ethers; Gui | 1981 |
Mechanism of smooth muscle relaxation by tiropramide.
Topics: Animals; Calcium; Colon; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Indometh | 1981 |
Slow-reacting substance from alveolar macrophages--a mechanism of asthma?
Topics: Animals; Asthma; Atropine; Autacoids; Chromones; Cimetidine; Ethers; Guinea Pigs; Indomethacin; Macr | 1981 |
The effect of indomethacin on contractions of guinea-pig stomach following cessation of vagal stimulation in the presence of hyoscine or pempidine.
Topics: Animals; Dinoprostone; Electric Stimulation; Female; Guinea Pigs; Indomethacin; Male; Muscle Contrac | 1981 |
C5a-induced aortic contraction: effect of an antihistamine and inhibitors of arachidonate metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspi | 1982 |
Prejunctional inhibition mediated via alpha 2-adrenoceptors in excitatory transmission of canine small intestine.
Topics: Adrenergic alpha-Agonists; Animals; Dogs; Electric Stimulation; Female; In Vitro Techniques; Indomet | 1982 |
Contractile actions of lysophosphatidic acids with a chemically-defined fatty acyl group on longitudinal muscle from guinea-pig ileum.
Topics: Animals; Chemical Phenomena; Chemistry; Drug Interactions; Fatty Acids; Guinea Pigs; Ileum; In Vitro | 1982 |
The contractile action of slow reacting substance of anaphylaxis (SRS-A) on rat isolated fundic strip and guinea-pig isolated ileum and its antagonism by FPL 55712.
Topics: Animals; Chromones; Gastric Fundus; Ileum; In Vitro Techniques; Indomethacin; Muscle Contraction; Mu | 1982 |
In vitro effect of acetylcholine and bethanechol on the contractions of the human detrusor muscle. Influence of prostaglandins.
Topics: Acetylcholine; Adult; Aged; Aspirin; Bethanechol Compounds; Humans; In Vitro Techniques; Indomethaci | 1982 |
The modulation of adrenergic airway tone in normal and ascaris-sensitive beagle dogs.
Topics: Adrenergic alpha-Agonists; Animals; Ascaris; Dinoprost; Dogs; Female; Hypersensitivity; In Vitro Tec | 1982 |
Neurotransmission in activation of the contractile response in the human urinary bladder.
Topics: Acetylcholine; Adult; Aged; Animals; Atropine; Cats; Dose-Response Relationship, Drug; Electric Stim | 1983 |
Neurotransmitted effect of prostaglandin F2 alpha in isolated cat jejunum.
Topics: Acetylcholine; Animals; Atropine; Cats; Dinoprost; Drug Interactions; Electric Stimulation; Hexameth | 1983 |
Antihistaminic versus anticholinergic effects of atropine on canine trachealis muscle.
Topics: Animals; Atropine; Dogs; Electric Stimulation; Histamine; Histamine H1 Antagonists; In Vitro Techniq | 1983 |
Pharmacological alteration of antigen-induced contraction of lung parenchymal strips isolated from the actively sensitized guinea pig.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Antigens; Drug Interactions; Female; Guinea Pigs; Histamin | 1983 |
Relaxant effects of vasoactive intestinal peptide and bethanechol in cat intrapulmonary artery.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Cats; Drug Interactions; Female; In Vitro Tec | 1983 |
Influence of ricinoleic acid on the contractions elicited by PGE2 on the guinea-pig ileum.
Topics: Animals; Dinoprostone; Fatty Acids, Unsaturated; Female; Guinea Pigs; Ileum; In Vitro Techniques; In | 1984 |
Relaxation and contraction responses to histamine in the human lung parenchymal strip.
Topics: Cimetidine; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Histamine H2 Anta | 1984 |
A study of the atropine-resistant component of the neurogenic response of the rabbit urinary bladder.
Topics: Animals; Atropine; Capsaicin; Chlorpheniramine; Drug Resistance; In Vitro Techniques; Indomethacin; | 1984 |
Prostaglandin-induced inhibition of acetylcholine release from neuronal elements of dog tracheal tissue.
Topics: Acetylcholine; Animals; Atropine; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-ac | 1984 |
Mechanical trauma to bladder epithelium liberates prostanoids which modulate neurotransmission in rabbit detrusor muscle.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bethanechol; Bethanechol Compounds; Carbachol; Dose-Response | 1984 |
Contribution of endogenous prostaglandins to excitation of the myenteric plexus of guinea-pig ileum: are adrenergic factors involved?
Topics: Acetylcholine; Animals; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydraz | 1984 |
The effect of indomethacin and adenosine 5'-triphosphate on the excitatory innervation of the rate urinary bladder.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Electric Stimulation; Indomethacin; Muscle Contracti | 1980 |
The effect of indomethacin and substance P on the guinea pig urinary bladder.
Topics: Animals; Atropine; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Mus | 1981 |
Release of leukotrienes from guinea pig lung stimulated by C5ades Arg anaphylatoxin.
Topics: Anaphylatoxins; Animals; Chromatography, High Pressure Liquid; Complement C5; Complement C5a; Cystei | 1982 |
Factors determining the site of chronic gastroduodenal ulcers.
Topics: Animals; Aspirin; Chronic Disease; Diet; Digestive System; Duodenum; Gastric Acid; Gastric Mucins; G | 1982 |
Pharmacological effects of peptides on tracheal smooth muscle.
Topics: Animals; Carbachol; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle | 1982 |
Effects of C5a on guinea pig lung: histamine release and mechanism of contraction.
Topics: Animals; Aspirin; Atropine; Chromones; Complement C5; Complement C5a; Dose-Response Relationship, Im | 1983 |
Partial agonists and antagonists for substance P.
Topics: Animals; Atropine; Diphenhydramine; Dogs; Guinea Pigs; In Vitro Techniques; Indomethacin; Muscle Con | 1983 |
Response of urethral smooth muscles to pharmacological agents. II. Noncholinergic, nonadrenergic agonists and antagonists.
Topics: Animals; Autonomic Agents; Bradykinin; Cats; Dinoprost; Dinoprostone; Female; In Vitro Techniques; I | 1983 |
[Action of adenosine 5'-triphosphate and effects of various purinergic receptor blocking agents on the movements of an isolated guinea pig gallbladder].
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Apamin; Atropine; Female; Gallbladder; | 1983 |
Receptors for substance P. I. The pharmacological preparations.
Topics: Animals; Atropine; Diphenhydramine; Dogs; Female; Guinea Pigs; Heart; Ileum; In Vitro Techniques; In | 1984 |
Studies on the relationship between contraction and mediator release produced by ovalbumin in superfused trachea isolated from the actively sensitized guinea pig.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Carbachol; Chromones; Dose-Response Relationship, Drug; Fe | 1984 |
Release of slow reacting substance from the guinea-pig lung by phospholipases A2 of Vipera russelli snake venom.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Thoracic; Autacoids; Blood Pressure; Guinea Pigs; Hist | 1984 |
Biological activity of leukotriene C4 in guinea pigs: in vitro and in vivo studies.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Pressure; Bradykinin; Epoprostenol; Guinea Pigs; Histamin | 1982 |
Prostaglandins and the cerebral circulation.
Topics: Animals; Arachidonic Acids; Brain; Cerebrovascular Circulation; Dinoprost; Energy Metabolism; Histor | 1983 |
Effects of 2-nicotinamidoethyl nitrate (SG-75, nicorandil) on indomethacin-induced contractions of isolated dog coronary arteries.
Topics: Animals; Coronary Vessels; Depression, Chemical; Dogs; Epoprostenol; In Vitro Techniques; Indomethac | 1983 |
Prostaglandins and angioplasty. An experimental study in canine arteries.
Topics: Angioplasty, Balloon; Animals; Aspirin; Carotid Arteries; Cyclooxygenase Inhibitors; Dogs; Epoproste | 1983 |
Mating call phonotaxis in the female American toad: induction by hormones.
Topics: Abdominal Muscles; Acoustic Stimulation; Animals; Bufonidae; Chorionic Gonadotropin; Dinoprost; Estr | 1984 |
Comparative effects of etodolac, indomethacin, and benoxaprofen on icosanoid biosynthesis.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Arachidonate Lipoxygenases; Blood Platelets; Catechols; | 1984 |
Prostaglandins and potassium relaxation in vascular smooth muscle of the rat. The role of Na-K ATPase.
Topics: Animals; Arteries; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascul | 1980 |
Blockage of partially obstructed coronary arteries with platelet thrombi: comparison between its prevention with cyclooxygenase inhibitors versus prostacyclin.
Topics: Animals; Aorta; Arachidonic Acids; Aspirin; Coronary Vessels; Cyclic AMP; Cyclooxygenase Inhibitors; | 1980 |
Aspects of prostaglandin action on autonomic neuroeffector transmission.
Topics: Adrenergic Fibers; Animals; Cattle; Cholinergic Fibers; Guinea Pigs; Ileum; Indomethacin; Iris; Kidn | 1980 |
Specific receptors for prostaglandins in airways.
Topics: Animals; Aspirin; Atropine; Bronchi; Cats; Epoprostenol; Female; Guinea Pigs; Histamine; Humans; Ind | 1980 |
Mechanism of physiological hypoxia-induced depression of vascular smooth muscle contraction.
Topics: Animals; Biological Transport, Active; Calcium; Energy Metabolism; In Vitro Techniques; Indomethacin | 1980 |
Cyclic nucleotides and contraction/relaxation in airway muscle: H1 and H2 agonists and antagonists.
Topics: Animals; Cimetidine; Cyclic AMP; Cyclic GMP; Ethylamines; Female; Guinea Pigs; Histamine; Histamine | 1980 |
The action of leukotriene B4 (LTB4) on the lung.
Topics: Animals; Arachidonic Acids; Chromones; Ethers; Guinea Pigs; Histamine; Humans; In Vitro Techniques; | 1980 |
beta-Adrenoceptor activation induces prostaglandin E2 generation in guinea-pig trachea.
Topics: Albuterol; Animals; Guinea Pigs; In Vitro Techniques; Indomethacin; Isoproterenol; Male; Muscle Cont | 1981 |
Tolerance of guinea-pig airway muscle preparations to relaxant agonists induced by chronic exposure to isoprenaline in vivo.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Female; Guinea Pigs; Histamine; In Vitro | 1981 |
Neuromuscular transmission in the corpus-fundus of the urinary bladder. An in vitro study in the cat.
Topics: Animals; Atropine; Cats; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Indomethacin | 1981 |
Role of Ca2+ in non-cholinergic, non-adrenergic responses to nerve stimulation of the guinea-pig small intestine.
Topics: Adenosine Triphosphate; Animals; Atropine; Calcium; Electric Stimulation; Guinea Pigs; In Vitro Tech | 1982 |
Relationship between the Ba-induced contraction and cyclic AMP levels in the isolated longitudinal smooth muscle from guinea pig ileum.
Topics: Animals; Barium; Cyclic AMP; Guinea Pigs; Ileum; Imidazoles; In Vitro Techniques; Indomethacin; Male | 1982 |
Pharmacological characterization of purinergic receptors in the rat vas deferens.
Topics: Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Muscle Contractio | 1983 |
Leukotriene C4-induced cyclic nucleotide changes and contractile response in guinea pig trachea.
Topics: Animals; Cyclic AMP; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smooth; SRS-A; Trachea | 1982 |
Vascular reactivity and high dietary eicosapentaenoic acid.
Topics: Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Dietary Fats; Eicosapentaenoic Acid; Fatty Acid | 1982 |
A possible negative feedback control of excitatory transmission via prostaglandins in canine small intestine.
Topics: Acetylcholine; Animals; Atropine; Dogs; Electric Stimulation; Feedback; Female; In Vitro Techniques; | 1980 |
Effects of selected bronchodilators on antigen- and A23187-induced contraction of guinea-pig trachea.
Topics: Aminophylline; Animals; Anti-Bacterial Agents; Antigens; Bronchodilator Agents; Bucladesine; Calcimy | 1983 |
Desensitization of beta-adrenoceptor in guinea pig trachea: a link with the prostaglandin system.
Topics: Animals; Bronchi; Dinoprostone; Guinea Pigs; Humans; Indomethacin; Isoproterenol; Male; Muscle Contr | 1983 |
Response of bovine intra-ocular muscles to transmural stimulation in the presence of various prostaglandins.
Topics: Action Potentials; Alprostadil; Animals; Cattle; Ciliary Body; Dinoprost; Dinoprostone; Electric Sti | 1983 |
The actions of leukotrienes B4, C4, D4 and E4 in the lung.
Topics: Animals; Guinea Pigs; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Leukotriene B4; Leukotr | 1983 |
Is prostacyclin subserving a vasodilator effect of methoxamine involving alpha adrenoreceptors?
Topics: Animals; Aorta, Abdominal; Epoprostenol; Indomethacin; Male; Methoxamine; Muscle Contraction; Platel | 1983 |
Direct effects of adenosine and adenine nucleotides on isolated human urinary bladder and their influence on electrically induced contractions.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adult; Aged; Atropine; Dipyri | 1983 |
Mechanism of canine coronary artery relaxation by monensin.
Topics: Aminophylline; Animals; Coronary Vessels; Denervation; Dogs; Dose-Response Relationship, Drug; Femal | 1983 |
Contractile reaction of isolated frog aorta after X-irradiation.
Topics: Animals; Aorta; Atropine; Cyclic AMP; Indomethacin; Methysergide; Muscle Contraction; Muscle, Smooth | 1983 |
Alpha adrenergic stimulation modified prostaglandins release in vas deferens.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Indomethacin; Male; Methoxamine; Mice; Muscle Contracti | 1983 |
Decreased lung beta-adrenoceptor function induced by 15-hydroperoxyarachidonic acid.
Topics: Animals; Arachidonic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Leukotriene | 1984 |
Effect of C3a and C5a anaphylatoxins on guinea-pig isolated blood vessels.
Topics: Anaphylatoxins; Animals; Aspirin; Blood Vessels; Chromones; Complement C3; Complement C3a; Complemen | 1984 |
Contraction of guinea pig lung by synthetic oligopeptides related to human C3a.
Topics: Acetylcholine; Animals; Chromones; Complement C3; Complement C3a; Guinea Pigs; In Vitro Techniques; | 1984 |
Relaxation of human isolated pulmonary arteries by prostacyclin (PGI2).
Topics: Adult; Aged; Dinoprost; Dose-Response Relationship, Drug; Electric Stimulation; Epoprostenol; Female | 1983 |
Effects of indomethacin and prostaglandins I2 and E2 on the tone of human isolated mesenteric arteries.
Topics: Adult; Aged; Dinoprostone; Electric Stimulation; Epoprostenol; Humans; In Vitro Techniques; Indometh | 1983 |
Prostacyclin modulates the responses to leukotrienes C4 and D4 of guinea-pig airway smooth muscle.
Topics: Acetylcholine; Animals; Epoprostenol; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Mu | 1984 |
C3a-induced contraction of guinea pig lung parenchyma: role of cyclooxygenase metabolites.
Topics: Animals; Aspirin; Complement C3; Complement C3a; Guinea Pigs; Humans; In Vitro Techniques; Indometha | 1983 |
Possible mechanisms involved in the spontaneous rhythmicity in the guinea-pig tracheal smooth muscle as induced by glucose removal.
Topics: Animals; Atropine; Calcimycin; Female; Glucose; Guinea Pigs; In Vitro Techniques; Indomethacin; Male | 1983 |
Effects of inhibitors of arachidonic acid metabolism and calcium entry on responses to acetylcholine, potassium and norepinephrine in the isolated canine saphenous vein.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium Channel Blockers; Dogs | 1983 |
The lipoxygenase pathway and tracheal muscle contraction.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Anima | 1983 |
Suppression of lymphatic vessel contractility with inhibitors of arachidonic acid metabolism.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arach | 1983 |
[Responses of isolated hepatic artery segments to barium in the presence of a flavonoid (4-methylesculetin), indomethacin and acetylsalicylate].
Topics: Animals; Aspirin; Barium; Hepatic Artery; Indomethacin; Lysine; Muscle Contraction; Scopoletin; Shee | 1983 |
Investigation of the role of prostaglandins in nitroglycerin-induced relaxation of isolated rabbit blood vessels.
Topics: Animals; Arachidonic Acids; Bradykinin; Celiac Artery; In Vitro Techniques; Indomethacin; Male; Mese | 1983 |
Endothelium-dependent relaxation of rabbit aorta. I. Relaxation stimulated by arachidonic acid.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Cate | 1983 |
Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Bacterial Agents; Aorta, Thoracic; Arachidonic Acid; | 1983 |
Release of leukotriene C4 from guinea pig trachea.
Topics: Animals; Antioxidants; Calcimycin; Catechols; Chromatography, High Pressure Liquid; Guinea Pigs; Ind | 1983 |
Protein synthesis in isolated rabbit forelimb muscles. The possible role of metabolites of arachidonic acid in the response to intermittent stretching.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; In Vitro Techniques; Indomethacin; Meclofenam | 1983 |
Endothelial-dependent relaxant effects of vaso-active intestinal polypeptide and arachidonic acid in rat aortic strips.
Topics: Acetylcholine; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Endothelium; Histamine; In Vitro | 1984 |
The importance of endogenous prostaglandins other than prostacyclin, for the modulation of contractility of some rabbit blood vessels.
Topics: Angiotensin II; Animals; Arteries; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Female; In | 1984 |
Role of calcium in arachidonic acid-induced contractions of guinea pig airways.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium Channel Blockers; Edetic Acid; Gallic | 1984 |
Differential contractile responsiveness of isolated rabbit arteries from different vascular beds to cyclooxygenase inhibitors and PGI2.
Topics: Animals; Arteries; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation | 1984 |
Effects of cyclooxygenase inhibitors, prostaglandins F2 alpha and I2, on isolated coeliac and basilar arteries of alloxan-diabetic dogs.
Topics: Animals; Basilar Artery; Body Weight; Celiac Artery; Cyclooxygenase Inhibitors; Diabetes Mellitus, E | 1984 |
Pharmacological studies into cyclo-oxygenase, lipoxygenase and phospholipase in smooth muscle contraction in the isolated trachea.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate Lipoxygenases; C | 1984 |
Cyclo-oxygenase inhibitors antagonize indirectly evoked contractions of the guinea-pig isolated ileum by inhibiting acetylcholine release.
Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Dinoprostone; Electric Stimulation; Female; Guine | 1984 |
Evidence for the involvement of arachidonic acid metabolites in spontaneous and drug-induced contractions of rat urinary bladder.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspir | 1984 |
Bronchoconstriction induced by N-formyl-methionyl-leucyl-phenylalanine in the guinea pig; involvement of arachidonic acid metabolites.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Bronchi; Chromones; Dose-Response Rela | 1984 |
Actions of lipoxygenase metabolites in isolated rat lungs.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Chromones; Dieth | 1984 |
Hypersensitivity to norepinephrine in vasa deferentia from diabetic rats. Possible participation of metabolic products of arachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Carbon Radioisotopes; Catechols; Diabetes Mel | 1984 |
Effects of cyclooxygenase inhibitors and PGI2 on the adrenergic contractions of isolated rabbit arteries.
Topics: Animals; Arteries; Cyclooxygenase Inhibitors; Electric Stimulation; Epoprostenol; In Vitro Technique | 1984 |
Spasmogenic activity of C5adesArg anaphylatoxin on guinea pig lung parenchymal strips: sensitivity of the leukotriene-mediated component to cyclooxygenase inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Complement C5; Complement C5a, des-Argini | 1984 |
Gamma-aminobutyric acid-induced contraction of the dog basilar artery.
Topics: Animals; Arachidonic Acids; Aspirin; Basilar Artery; Bicuculline; Dogs; Drug Interactions; Ethanol; | 1984 |
Cholinergic responses in the human lung parenchymal strip: a structure-function correlation.
Topics: Aged; Carbachol; Female; Histamine; Humans; Indomethacin; Lung; Male; Middle Aged; Muscle Contractio | 1984 |
Histamine-induced rhythmic contraction of hog carotid artery smooth muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Carotid Arteries; Electrophysiology; Female; Hist | 1984 |
Mechanisms of the ergonovine-induced vasoconstriction in the rabbit main coronary artery.
Topics: Acetylcholine; Animals; Coronary Vessels; Electric Stimulation; Electrophysiology; Ergonovine; Femal | 1984 |
Study of mechanisms mediating contraction to leukotriene C4, D4 and other bronchoconstrictors on guinea pig trachea.
Topics: Acetylcholine; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Guinea Pigs; His | 1984 |
Tetrodotoxin-resistant relaxation to transmural nerve stimulation in isolated saphenous vein.
Topics: Aminophylline; Animals; Biomechanical Phenomena; Cimetidine; Cyproheptadine; Dogs; Drug Resistance; | 1984 |
Phentolamine-induced rhythmic contractions in bladder detrusor muscle of guinea-pig.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Indomethacin; | 1984 |
[Effect of indomethacin on leukotriene-induced contractile responses in guinea pig trachea and lung parenchyma strips].
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; In Vitro Techniques; Indo | 1984 |
The role of prostaglandins in the spontaneous and cholinergic nerve-mediated motility of guinea-pig gastric muscle.
Topics: Alprostadil; Animals; Dinoprost; Dinoprostone; Electric Stimulation; Female; Guinea Pigs; In Vitro T | 1983 |
Separation of the two components of the contractile activity of leukotriene C4 on the guinea pig lung parenchymal strip.
Topics: Animals; Biological Assay; Guinea Pigs; Indomethacin; Lung; Muscle Contraction; Muscle, Smooth, Vasc | 1983 |
The influence of changes in tension on protein synthesis and prostaglandin release in isolated rabbit muscles.
Topics: Animals; Calcium; Dinoprost; In Vitro Techniques; Indomethacin; Meclofenamic Acid; Muscle Contractio | 1983 |
Role of prostaglandins in regulating gastric motility.
Topics: Animals; Dinoprostone; Dogs; Electric Conductivity; Gastrointestinal Motility; Indomethacin; Muscle | 1984 |
Decreased contractility of the ductus arteriosus in experimental pulmonic stenosis.
Topics: Animals; Dinoprostone; Disease Models, Animal; Ductus Arteriosus; Female; Hemodynamics; Indomethacin | 1984 |
Leukotriene-induced contraction and thromboxane production in guinea-pig lung parenchymal strips.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Dinoprost; Female; Guinea Pigs; In Vitro Techniques; | 1984 |
Effect of indomethacin on stretch-induced uterine activity in the post-partum.
Topics: Female; Humans; Indomethacin; Labor, Obstetric; Muscle Contraction; Muscle Relaxation; Postpartum Pe | 1983 |
Studies of the mechanism of passive anaphylaxis in human airway smooth muscle.
Topics: Anaphylaxis; Antigens; Arachidonic Acids; Bronchi; Chromones; Histamine; Humans; Immunoglobulin E; I | 1983 |
Bioassays of smooth muscle contracting agents in cotton mill dust and bract extracts: arachidonic acid metabolites as possible mediators of the acute byssinotic reaction.
Topics: Acute Disease; Animals; Arachidonic Acids; Byssinosis; Diphenhydramine; Dust; Gossypium; In Vitro Te | 1983 |
Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Blood Platelets; Catechols; Chromones; Dose-Respo | 1983 |
[Effect of a flavinoid (4-methylesculetin) on the response of isolated calf coronary arteries to histamine in the presence of indomethacin].
Topics: Animals; Cattle; Coronary Vessels; Histamine; Indomethacin; Muscle Contraction; Muscle Relaxation; M | 1983 |
[Response of isolated coronary artery segments to serotonin in the presence of a flavinoid, indomethacin and acetylsalicylate].
Topics: Animals; Ascorbic Acid; Aspirin; Cattle; Coronary Vessels; Indomethacin; Muscle Contraction; Muscle | 1983 |
[Effect of a bioflavinoid (4-methylesculetin) on the response of calf hepatic arteries to serotonin in the presence of indomethacin].
Topics: Animals; Cattle; Hepatic Artery; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth | 1983 |
Electrical activities of the muscle layers of the canine colon.
Topics: Action Potentials; Animals; Atropine; Colon; Dogs; Female; In Vitro Techniques; Indomethacin; Male; | 1983 |
The effect of leukotriene D4 on the isolated stomach and colon of the rat.
Topics: Animals; Chromones; Colon; Dose-Response Relationship, Drug; Indomethacin; Male; Muscle Contraction; | 1983 |
Adenosine and ATP effects on isolated guinea pig gallbladder.
Topics: Adenosine; Adenosine Triphosphate; Animals; Culture Techniques; Drug Interactions; Gallbladder; Guan | 1983 |
Sensitivity to indomethacin of tetrodotoxin-resistant contractions of smooth muscle from the base of rabbit bladder.
Topics: Animals; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins | 1983 |
The effect of indomethacin on the contractile response of the guinea-pig lung parenchymal strip to leukotrienes B4, C4, D4 and E4.
Topics: Animals; Clotrimazole; Drug Interactions; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male | 1983 |
Evidences for involvement of prostaglandins of the E series in morphine physical dependence in the isolated ileum of the guinea-pig.
Topics: Acetylcholine; Animals; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indomethacin; Male; Morphin | 1983 |
The effects of platelet-derived contractile agents on human digital arteries.
Topics: Arteries; Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Ketanserin; Muscle | 1984 |
Potentiating effect of indomethacin on relaxations of sheep isolated coronary artery caused by sympathetic nerve stimulation or exogenous noradrenaline.
Topics: Animals; Coronary Vessels; Electric Stimulation; In Vitro Techniques; Indomethacin; Muscle Contracti | 1984 |
C-6-sulfidopeptide leukotrienes are unlikely to be involved in the endothelium dependent relaxation of rabbit aorta by acetylcholine.
Topics: Acetylcholine; Animals; Aorta; Cyclohexanones; Endothelium; Female; Guinea Pigs; Ileum; In Vitro Tec | 1984 |
Cytochrome P 450-linked monooxygenase: involvement in the lamb ductus arteriosus.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Ductus Arteriosus; Female; Guinea Pigs; In | 1984 |
Autonomic mechanisms in the ductus venosus of the lamb.
Topics: Acetylcholine; Adrenergic Fibers; Animals; Animals, Newborn; Atropine; Electric Stimulation; Indomet | 1984 |
The response of the lamb ductus venosus to prostaglandins and inhibitors of prostaglandin and thromboxane synthesis.
Topics: Animals; Animals, Newborn; Depression, Chemical; Dinoprostone; Epoprostenol; Female; Fetal Organ Mat | 1982 |
A possible role for lipoxygenase products as regulators of airway smooth muscle reactivity.
Topics: Animals; Arachidonic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; In Vitro Techn | 1980 |
Effects of indomethacin on prostaglandin synthesis and on contractile response of the guinea pig gallbladder.
Topics: Animals; Female; Gallbladder; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contracti | 1981 |
Contraction of the canine basilar artery following linoleic, arachidonid 13-hydroperoxylinoleic, or 15-hydroperoxyarachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arteries; Dogs; Female; In Vitro Techniques; Indometha | 1981 |
A proposed role for prostaglandins in the modulation of the relaxation response to urotensin I in isolated rat arteries.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arteries; Aspirin; Atropine; Dose-Response Relationshi | 1981 |
The effect of indomethacin on spontaneous and human menopausal gonadotropin induced pressure changes in the tissue and arterial vascular system from human ovaries perfused in vitro.
Topics: Adult; Arteries; Blood Pressure; Female; Humans; Indomethacin; Menotropins; Middle Aged; Muscle Cont | 1982 |
The effect of inhibitors of arachidonic acid metabolism on drug-induced contractions in isolated tracheal smooth muscle of the pig.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Dexame | 1982 |
Possible mechanisms of 15-hydroperoxyarachidonic acid-induced contraction of the canine basilar artery in vitro.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Basilar Artery; Biotransformation; Dogs; Epoprostenol; | 1982 |
Effect of ETYA and BW 755c on arachidonate-induced contractions in the guinea-pig isolated trachea.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Airwa | 1982 |
Effects of indomethacin on contractility of isolated human umbilical artery.
Topics: Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Dinoprost; Drug Interactions; Female; H | 1982 |
The effects of indomethacin and prostaglandin E2 (PGE2) on acetylcholine-initiated contractions of gastric muscularis muscle of Bufo marinus.
Topics: Acetylcholine; Animals; Bufo marinus; Dinoprostone; Drug Interactions; In Vitro Techniques; Indometh | 1982 |
Antigen-induced contraction of guinea-pig trachea: search for mediator release with cascade superfusion bioassay.
Topics: Animals; Antigens; Arachidonic Acid; Arachidonic Acids; Guinea Pigs; In Vitro Techniques; Indomethac | 1982 |
The effect of mixed inhibitors of cyclo-oxygenase and lipoxygenase on the indomethacin-induced hyper-reactivity in the isolated trachea of the pig.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Airway Resistance; Animals; Cyclooxyge | 1982 |
The effect of contraction and Ca2+ removal on the indomethacin-induced increase in tracheal smooth muscle reactivity.
Topics: Animals; Calcium; Egtazic Acid; Histamine; In Vitro Techniques; Indomethacin; Muscle Contraction; Sw | 1982 |
Vascular effects of hyperthermia on isolated blood vessels.
Topics: Animals; Female; Hot Temperature; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Mus | 1983 |
The effect of lysophosphatidylcholine on gallbladder function in the cat.
Topics: Animals; Bile; Blood Proteins; Cats; Female; Gallbladder; Hexosamines; Indomethacin; Lysophosphatidy | 1983 |
C5a and antigen-induced tracheal contraction: effect of a combination of an antihistamine and cyclo-oxygenase inhibitors.
Topics: Animals; Antigens; Aspirin; Complement C5; Complement C5a; Diphenhydramine; Drug Synergism; Ethanol; | 1983 |
The effect of prostaglandin E2 on histamine-stimulated calcium mobilization as a possible explanation for histamine tachyphylaxis in canine tracheal smooth muscle.
Topics: Acetylcholine; Animals; Calcium; Dogs; Drug Interactions; Histamine; In Vitro Techniques; Indomethac | 1983 |
Anoxia and endothelium-dependent reactivity of the canine femoral artery.
Topics: Animals; Barium; Dogs; Endothelium; Femoral Artery; Glucose; In Vitro Techniques; Indomethacin; Musc | 1983 |
Contraction of isolated airway smooth muscle by synthetic leukotrienes C4 and D4.
Topics: Animals; Arachidonic Acids; Bronchi; Chromones; Ethers; Guinea Pigs; In Vitro Techniques; Indomethac | 1981 |
Comparative potency and pharmacology of isomers of leukotriene D4 on guinea-pig trachea: requirement for a 5(S)6(R) configuration.
Topics: Animals; Chromones; Guinea Pigs; Indomethacin; Isomerism; Male; Muscle Contraction; Muscle, Smooth; | 1982 |
Biological activity of leukotriene sulfones on respiratory tissues.
Topics: Animals; Blood Pressure; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle Con | 1982 |
Copper and contractility of the human fallopian tube.
Topics: Adult; Copper; Dinoprost; Dose-Response Relationship, Drug; Fallopian Tubes; Female; Humans; Indomet | 1981 |
Contractile responses of longitudinal and circular smooth muscle of the canine stomach to prostaglandins E and F2alpha.
Topics: Acetylcholine; Animals; Dogs; Female; Gastric Mucosa; In Vitro Techniques; Indomethacin; Male; Muscl | 1982 |
Age-dependent sensitivity of the lamb ductus arteriosus to indomethacin and prostaglandins.
Topics: Animals; Ductus Arteriosus; Epoprostenol; Gestational Age; Humans; Indomethacin; Infant, Newborn; In | 1980 |
Effects of various prostanoids on gallbladder muscle.
Topics: Animals; Dose-Response Relationship, Drug; Epoprostenol; Gallbladder; Guinea Pigs; Humans; Hydrostat | 1980 |
Effect of exogenous and endogenous prostacyclin on the contractility of rabbit splenic capsular smooth muscle.
Topics: Animals; Arachidonic Acids; Epoprostenol; Fatty Acids; In Vitro Techniques; Indomethacin; Muscle Con | 1980 |
Prostacyclin (PGI2) mediates hypoxic relaxation of bovine coronary arterial strips.
Topics: Animals; Arachidonic Acids; Arteries; Cattle; Coronary Vessels; Epoprostenol; Hypoxia; Indomethacin; | 1981 |
Effects on prostaglandins F2 alpha, I2, and indomethacin on isolated coronary arteries from healthy and alloxan-diabetic dogs.
Topics: Animals; Arteries; Coronary Vessels; Diabetes Mellitus, Experimental; Dinoprost; Dogs; Drug Synergis | 1981 |
Aggregation of platelets induced by novel synthetic secoprostaglandins.
Topics: Animals; Epoprostenol; Hemodynamics; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, | 1981 |
Hypoventilation and elevation of end-expiratory pressure release a substance which relaxes isolated arteries and disaggregates platelets in the presence of cyclooxygenase inhibitors.
Topics: Animals; Aspirin; Biological Assay; Cats; Cattle; Dogs; Epoprostenol; Hypoventilation; Indomethacin; | 1981 |
Evidence for a prostaglandin link in the purinergic activation of rabbit bladder smooth muscle.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbachol; In Vitro Techniques; Indomethacin; Muscle Contr | 1982 |
Effects of SRS (slow reacting substance) on cyclic nucleotides in guinea pig tracheal muscle.
Topics: Animals; Chromones; Female; Guinea Pigs; Hypersensitivity; Indomethacin; Male; Muscle Contraction; M | 1982 |
Investigation of relaxations of the rabbit anococcygeus muscle by nerve stimulation and ATP using the ATP antagonist ANAPP3.
Topics: Adenosine; Adenosine Triphosphate; Animals; Azides; Electric Stimulation; In Vitro Techniques; Indom | 1982 |
Enhancement by levamisole of the contractions induced by prostaglandin E2 in the guinea-pig isolated ileum.
Topics: Animals; Atropine; Bradykinin; Drug Synergism; Guinea Pigs; Hexamethonium Compounds; Histamine; Ileu | 1982 |
Comparison of contractions of the smooth muscle of the guinea-pig vas deferens induced by ATP and related nucleotides.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dose-Response Relations | 1982 |
The interactions of platelet-derived mediators on isolated canine coronary arteries.
Topics: Animals; Blood Platelets; Coronary Vessels; Dogs; Female; In Vitro Techniques; Indomethacin; Male; M | 1982 |
Prostaglandins and the contractility of the guinea pig biliary system.
Topics: Acetylcholine; Animals; Biliary Tract; Electric Stimulation; Female; Gallbladder; Guinea Pigs; In Vi | 1981 |
Spontaneous activity in the trachea of dogs treated with indomethacin: an experimental model for aspirin-related asthma.
Topics: Animals; Aspirin; Asthma; Atropine; Disease Models, Animal; Dogs; Female; Indomethacin; Male; Muscle | 1981 |
Hypogastric nerve from guinea-pig releases prostaglandin-like substance.
Topics: Animals; Arachidonic Acids; Atropine; Gastric Fundus; Guinea Pigs; Hypogastric Plexus; In Vitro Tech | 1981 |
Vascular smooth muscle contraction induced by direct electrical stimulation and its subsequent effect of reactivity to agonists.
Topics: Animals; Arteries; Calcium; Electric Stimulation; Female; Histamine; In Vitro Techniques; Indomethac | 1981 |
Effects of tartrazine of different contractile stimuli in guinea pig tracheal muscle.
Topics: Animals; Arachidonic Acids; Azo Compounds; Carbachol; Guinea Pigs; Histamine Antagonists; Indomethac | 1981 |
Endogenous prostaglandins and spontaneous contractions in the circular muscle of the guinea-pig stomach.
Topics: Animals; Calcium; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Prostagl | 1980 |
The effect of cigarette smoke on the metabolism of arachidonic acid to myotropic compounds in rat and hamster isolated lungs.
Topics: Animals; Arachidonic Acids; Cricetinae; Culture Media; In Vitro Techniques; Indomethacin; Lung; Male | 1981 |
Indomethacin intravenously--a new way for effective relief of biliary pain: a double-blind study in man.
Topics: Adult; Aged; Blood Pressure; Cholelithiasis; Double-Blind Method; Female; Gallbladder; Humans; Indom | 1981 |
Biphasic dose-response relationship for acetylcholine in the chick jugular vein.
Topics: Acetylcholine; Animals; Aspirin; Atropine; Chickens; Dose-Response Relationship, Drug; Indomethacin; | 1981 |
Effects of ergotamine on isolated human vessels.
Topics: Adult; Aged; Drug Interactions; Ergotamine; Female; Humans; In Vitro Techniques; Indomethacin; Male; | 1981 |
Further investigations on potassium-induced automaticity of isolated human renal artery.
Topics: Adult; Aged; Aspirin; Bradykinin; Female; Humans; In Vitro Techniques; Indomethacin; Male; Middle Ag | 1981 |
An objective measurement of change in morning stiffness.
Topics: Arthritis, Rheumatoid; Female; Hand; Humans; Indomethacin; Male; Middle Aged; Muscle Contraction; Pr | 1981 |
Evidence for two types of excitatory receptor for 5-hydroxytryptamine in dog isolated vasculature.
Topics: Animals; Blood Vessels; Dogs; Female; Indomethacin; Male; Methoxamine; Methysergide; Muscle Contract | 1980 |
Role of prostaglandins in contractile activity of the ampulla of the rabbit oviduct.
Topics: Animals; Arachidonic Acids; Drug Therapy, Combination; Fallopian Tubes; Female; In Vitro Techniques; | 1980 |
Gastroenterology, prostaglandins, bradykinin, and rat ileum.
Topics: Animals; Bradykinin; Gastrointestinal Motility; Ileum; In Vitro Techniques; Indomethacin; Intestinal | 1980 |
Further studies of dog tracheobronchial smooth muscle.
Topics: Airway Resistance; Animals; Bronchi; Carbachol; Dogs; Drug Interactions; Histamine; Histamine Antago | 1980 |
Evidence for oscillation of prostaglandin release from spontaneously contracting guinea pig taenia coli.
Topics: Animals; Cell Communication; Colon; Guinea Pigs; In Vitro Techniques; Indomethacin; Muscle Contracti | 1980 |
The interaction between indomethacin and contractile agents on human isolated airway muscle.
Topics: Acetylcholine; Airway Resistance; Bronchi; Drug Interactions; Histamine; Humans; In Vitro Techniques | 1980 |
Stimulation of cholinergic nerves in dog intestine by adenine nucleotides.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Dogs; Dose-Response Relationship, Drug; Electr | 1980 |
The stimulant effect of prostaglandin F2 alpha on the longitudinal muscle of guinea pig caecum.
Topics: Action Potentials; Animals; Atropine; Cecum; Electric Stimulation; Evoked Potentials; Guinea Pigs; I | 1980 |
Effect of inhibition of arachidonic acid metabolism on anaphylaxis of guinea pig lung strips.
Topics: Anaphylaxis; Animals; Arachidonic Acids; Catechols; Dose-Response Relationship, Drug; Guinea Pigs; I | 1980 |
On the relation between contraction and prostaglandin release in rabbit mesenteric blood vessels.
Topics: Angiotensin II; Animals; Calcium; Female; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteri | 1980 |
Mechanisms of the responses to non-cholinergic, non-adrenergic nerve stimulation and to ATP in isolated rabbit urinary bladder: evidence for ADP evoked prostaglandin release.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Carbachol; Ele | 1980 |
Contribution of prostaglandins to the adenosine triphosphate-induced contraction of rabbit urinary bladder.
Topics: Adenosine Triphosphate; Animals; Carbachol; Drug Interactions; Electric Stimulation; Guinea Pigs; In | 1980 |
Contribution of prostaglandin to the contraction induced by catecholamines in the isolated gallbladder of the guinea-pig.
Topics: Animals; Catecholamines; Ceruletide; Common Bile Duct; Gallbladder; Guinea Pigs; Indomethacin; Muscl | 1980 |
Role of prostaglandins in the responses of rabbit detrusor to non-cholinergic, non-adrenergic nerve stimulation and to ATP.
Topics: Adenosine Triphosphate; Animals; Atropine; Electric Stimulation; Indomethacin; Muscle Contraction; M | 1980 |
Detrusor dynamics. II. Effect of prostaglandins and their synthesis inhibitor on stress-relaxation time course.
Topics: Animals; Biomechanical Phenomena; Cats; Female; Indomethacin; Male; Muscle Contraction; Muscle Relax | 1981 |
[Effect of prostaglandin F2 on the bladder muscles in women].
Topics: Female; Humans; Indomethacin; Manometry; Muscle Contraction; Muscle Tonus; Prostaglandins F; Urinary | 1980 |
The effects of time and indomethacin on contractile responses of the guinea-pig gall bladder in vitro.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Female; Gallbladder; Guinea Pigs; In Vitro | 1980 |
Aminoguanidine selectively inhibits inducible nitric oxide synthase.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Cimetidine; Endothelium, Vascular; End | 1993 |
Effect of cilazapril and indomethacin on endothelial dysfunction in the aortas of spontaneously hypertensive rats.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Aorta, Thoracic; Blood Pressure; Cilazapril; Dinopros | 1993 |
Endothelium-dependent contractions to endothelin in the rat aorta are mediated by thromboxane A2.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Bridged Bicyclo Compounds, Heterocyc | 1993 |
Endothelium-dependent relaxation to substance P in human umbilical artery is mediated via prostanoid synthesis.
Topics: Endothelium, Vascular; Humans; Indomethacin; Muscle Contraction; Potassium; Prostaglandins; Substanc | 1994 |
Sensitivity to protein kinase C inhibitors of nicardipine-insensitive component of high K+ contracture in rat and guinea-pig aorta.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta, Thoracic; Calcium; Guinea Pigs; Hyper | 1994 |
Involvement of apamin-sensitive K+ channels in antigen-induced spasm of guinea-pig isolated trachea.
Topics: Animals; Antigens; Apamin; Charybdotoxin; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro | 1994 |
Magnesium modulates endothelial dysfunction produced by elevated glucose incubation.
Topics: Acetylcholine; Analysis of Variance; Animals; Aorta; Diabetes Mellitus, Experimental; Disease Models | 1994 |
Endothelial modulation of vascular tone in isolated porcine and bovine basilar arteries.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Basilar Artery; Bradykinin; Cattle; Dose-Response Rel | 1994 |
Alterations of ex vivo vascular reactivity in intraperitoneal sepsis.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Body Temperature; Cecum; Disease Models, Animal; D | 1994 |
Pharmacological analysis of the local and reflex responses to bradykinin on rat urinary bladder motility in vivo.
Topics: Adrenergic beta-Antagonists; Animals; Bradykinin; Capsaicin; Dose-Response Relationship, Drug; Indol | 1995 |
Involvement of nitroxidergic and noradrenergic nerves in the relaxation of dog and monkey temporal veins.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amino Acid Oxidoreductases; Animals; Argi | 1995 |
Role of thromboxane A2 in bradykinin-induced human isolated small bronchi contraction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Biphenyl Compounds; | 1995 |
Evidence that tachykinin NK1 and NK2 receptors mediate non-adrenergic non-cholinergic excitation and contraction in the circular muscle of guinea-pig duodenum.
Topics: Action Potentials; Adenosine Diphosphate; Animals; Apamin; Arginine; Atropine; Dose-Response Relatio | 1995 |
The effect of lithium on endothelial-dependent relaxation in rat isolated aorta.
Topics: Animals; Aorta; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Lithium; Male; Muscle Cont | 1995 |
Effect of swimming on vascular reactivity to phenylephrine and KC1 in male rats.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Dose-Response Relationship, Drug; Endothel | 1995 |
Calcitonin gene-related peptide (CGRP)-enhanced non-adrenergic non-cholinergic contraction of guinea-pig proximal colon.
Topics: Animals; Atropine; Calcitonin Gene-Related Peptide; Colon; Electric Stimulation; Guanethidine; Guine | 1995 |
Vasorelaxant effect of the analgesic clonixin on rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
The effects of PGE2 and PGF2 alpha on rhythmic contractions of sphincter of Oddi.
Topics: Acetylcholine; Animals; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Female; Guinea Pi | 1995 |
Mechanisms of bradykinin-induced contraction of the guinea-pig gallbladder in vitro.
Topics: Animals; Bradykinin; Dinoprostone; Dose-Response Relationship, Drug; Female; Gallbladder; Guinea Pig | 1995 |
Sustained contraction produced by caffeine after ryanodine treatment in the circular muscle of the guinea-pig gastric antrum and rabbit portal vein.
Topics: Animals; Caffeine; Calcium; Carbachol; Colforsin; Female; Fura-2; Guinea Pigs; Indomethacin; Male; M | 1995 |
Contraction to endothelin-1 in pulmonary arteries from endotoxin-treated rats is modulated by endothelium.
Topics: Animals; Dioxanes; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; E | 1995 |
Attenuated Ca2+ response to acetylcholine in endothelial cells from aorta of aldosterone-salt hypertensive rats.
Topics: Acetylcholine; Aldosterone; Animals; Arginine; Calcium; Endothelium, Vascular; Fura-2; Hypertension; | 1995 |
15-Hydroxyeicosatetraenoic acid and diabetic endothelial dysfunction in rabbit aorta.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Bridged Bicyclo Compounds, Heterocyclic; Cytochrome P-450 | 1995 |
Potentiation by endothelin-1 of Ca2+ sensitivity of contractile elements depends on Ca2+ influx through L-type Ca2+ channels in the canine cerebral artery.
Topics: Animals; Arginine; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebral Arteries; Dogs; End | 1995 |
Effects of the peptide leukotriene receptor antagonist ICI 198,615 on the in vivo and in vitro changes in guinea pig bladder function which occur after sensitization with ovalbumin.
Topics: Animals; Female; Guinea Pigs; In Vitro Techniques; Indazoles; Indomethacin; Leukotriene Antagonists; | 1995 |
Effects of des-Asp-angiotensin I on the contractile action of angiotensin II and angiotensin III.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Aorta, Th | 1995 |
Platelets enhance anoxic contraction of rat aortic rings through platelet-activating factor-dependent mechanism.
Topics: Animals; Aorta, Thoracic; Blood Platelets; Buffers; Endothelium, Vascular; Free Radical Scavengers; | 1993 |
Pharmacologic modulation of the influence of the epithelium on immunologic- and nonimmunologic-induced histamine release and contraction in guinea pig superfused tracheal strips.
Topics: Animals; Epithelium; Female; Guinea Pigs; Histamine Release; Hydroxyurea; In Vitro Techniques; Indaz | 1993 |
Effect of frusemide on bradykinin- and capsaicin-induced contraction of the guinea-pig trachea.
Topics: Animals; Bradykinin; Bronchoconstriction; Capsaicin; Furosemide; Guinea Pigs; Indomethacin; Male; Mu | 1993 |
Endothelin-induced contraction and mediator release in human bronchus.
Topics: Acetylcholine; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Dicarboxylic Acids; Endot | 1993 |
Mechanical and biochemical responses to endothelin-1 and endothelin-3 in human bronchi.
Topics: Atropine; Bronchi; Calcium; Dose-Response Relationship, Drug; Endothelins; Glycopeptides; Humans; In | 1994 |
Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs.
Topics: Animals; Asthma; Benzoquinones; Disease Models, Animal; Etodolac; Guinea Pigs; Immunization, Passive | 1994 |
Cardiovascular actions of frog urotensin II in the frog, Rana catesbeiana.
Topics: Acetylcholine; Animals; Arachidonic Acid; Atropine; Blood Pressure; Cardiac Output; In Vitro Techniq | 1995 |
Contractile effects of prostanoids on fetal rabbit ductus arteriosus.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Analysis of Variance; Animals; C | 1995 |
Interactions between prostaglandins, muscarinic agonists and the adenylate cyclase and phospholipase C systems in dog ciliary smooth muscle.
Topics: Adenylyl Cyclases; Animals; Carbachol; Ciliary Body; Cyclic AMP; Dinoprostone; Dogs; Indomethacin; I | 1995 |
Diaphragmatic failure during group B streptococcal sepsis in piglets: the role of thromboxane A2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Gas Analysis; Bri | 1995 |
Endothelium-dependent relaxation resistant to NG-nitro-L-arginine in rat aorta.
Topics: Acetylcholine; Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Atropine; Biological Factor | 1995 |
Desensitization of platelet-activating factor receptors, induced by inflammation in guinea pig ileal smooth muscle cells.
Topics: Acetylcholine; Animals; Cell Survival; Dinoprostone; Diterpenes; Ginkgolides; Guinea Pigs; Ileitis; | 1995 |
Role of 5-hydroxytryptamine in mediating adenosine-induced airway contraction.
Topics: Analysis of Variance; Animals; Atropine; Diphenhydramine; Dose-Response Relationship, Drug; Epitheli | 1995 |
Effect of the vascular endothelium on noradrenaline-induced contractions in non-pregnant and pregnant guinea-pig uterine arteries.
Topics: Animals; Arginine; Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Guinea | 1995 |
Further investigations into adenosine A1 receptor-mediated contraction in rat colonic muscularis mucosae and its augmentation by certain alkylxanthine antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colon; Cyclooxygenase Inhibitors; In Vitro Te | 1995 |
Antagonism by paraquat of the relaxing effects of acetylcholine and A23187 in rat thoracic aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcimycin; Dinoprost; Endothelium, Vascular; Female; Free | 1995 |
Homologous desensitization of PAF receptors via a PGE2-dependent pathway on intestinal smooth muscle.
Topics: Acetophenones; Animals; Dinoprostone; Guinea Pigs; Ileum; Indomethacin; Kinetics; Male; Muscle Contr | 1994 |
Endothelium-dependent, nitric oxide-mediated inhibition of angiotensin II-induced contractions in rabbit aorta.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Arginine; Dose-Resp | 1994 |
Relaxation of human isolated mesenteric arteries by vasopressin and desmopressin.
Topics: Adult; Arginine; Arginine Vasopressin; Deamino Arginine Vasopressin; Endothelium, Vascular; Female; | 1994 |
Effects of intrinsic prostaglandins on the spontaneous contractile and electrical activity of the proximal renal pelvis of the guinea-pig.
Topics: Action Potentials; Animals; Dinoprost; Electric Stimulation; Electrophysiology; Guinea Pigs; In Vitr | 1994 |
Role of the endothelium in regulation of vascular functions in two teleosts.
Topics: Acetylcholine; Animals; Aorta; Arginine; Endothelins; Endothelium, Vascular; Epinephrine; Fishes; In | 1994 |
Modulation of contractions to and receptors for endothelins in canine veins.
Topics: Acetylcholine; Animals; Arteriovenous Shunt, Surgical; Binding, Competitive; Cell Membrane; Dinopros | 1995 |
Reversibility of tachyphylaxis to C5A in guinea pig tissues, perfused human placental lobule, and umbilical artery.
Topics: Animals; Complement C5a; Female; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indomethacin; Lung | 1994 |
Comparison of endothelial function between in situ and reversed vein graft: differences in endothelium-dependent responses.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Calcimycin; Carotid Artery, Common; Dogs; Endothelium | 1995 |
Pharmacological studies of stonefish (Synanceja trachynis) venom.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Captopril; Chromones; Dose-Response Relationship, Drug; | 1994 |
Spasmogenic actions of frog urotensin II on the bladder and ileum of the frog, Rana catesbeiana.
Topics: Animals; Atropine; Female; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscl | 1994 |
Assessment of agonist- and cell-mediated responses in airway microsections by computerized videomicrometry.
Topics: Acetylcholine; Animals; Computers; Eosinophils; Epithelium; Guinea Pigs; Humans; Indomethacin; Kinet | 1995 |
In vitro demonstration of a positive effect of rhein anthrone on peristaltic reflex of guinea pig ileum.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anthracenes; Dibenz(b,f)(1,4) | 1993 |
Predominance of endothelinA (ETA) receptors in ovine airway smooth muscle and their mediation of ET-1-induced contraction.
Topics: Animals; Autoradiography; Carbachol; Endothelin Receptor Antagonists; Endothelins; In Vitro Techniqu | 1994 |
Effects of exogenous and endogenous prostaglandins on the fast phase of contraction of the guinea-pig vas deferens produced by electrical field stimulation.
Topics: Animals; Arachidonic Acid; Dinoprostone; Electric Stimulation; Epoprostenol; Guinea Pigs; In Vitro T | 1994 |
Inhibition of vasoactive amine induced contractions of vascular smooth muscle by hydrogen peroxide in rabbit aorta.
Topics: Acetylcholine; Animals; Antioxidants; Aorta; Deferoxamine; Depression, Chemical; Endothelium, Vascul | 1994 |
Interactions between leukotrienes and histamine in the anaphylactic contraction of guinea pig lung parenchyma.
Topics: Anaphylaxis; Animals; Azepines; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Indomethacin; | 1994 |
Modulation of phorbol ester-induced contraction by endogenously released cyclooxygenase products in rat aorta.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Arachidonic Acid; Bridged Bicyclo Compounds, Heteroc | 1994 |
The human deferential artery: endothelium-mediated contraction in response to adrenergic stimulation.
Topics: Acetylcholine; Adult; Aged; Aged, 80 and over; Arginine; Arteries; Electric Stimulation; Endothelium | 1994 |
Endothelin receptors mediating functional responses in human small arteries and veins.
Topics: Arginine; Arteries; Endothelin Receptor Antagonists; Endothelins; Humans; In Vitro Techniques; Indom | 1994 |
Nitric oxide pathway-mediated relaxant effect of bradykinin in the guinea-pig isolated trachea.
Topics: Animals; Arginine; Bradykinin; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Femal | 1994 |
Occurrence of endothelium-derived relaxing factor--nitric oxide in the lamb ductus arteriosus.
Topics: Animals; Arginine; Bradykinin; Ductus Arteriosus; Endothelium, Vascular; Female; Fetus; Indomethacin | 1994 |
Atrial natriuretic peptide inhibits the purinergic and not the adrenergic component of electrically induced contractile responses in guinea pig vas deferens.
Topics: Adenosine Triphosphate; Adrenergic Antagonists; Animals; Atrial Natriuretic Factor; Electric Stimula | 1993 |
Vascular mode of action of kinin B1 receptors and development of a cellular model for the investigation of these receptors.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Thoracic; Bradykinin; Bradykinin Receptor Antagonists; | 1993 |
Selective hyperresponsiveness to ovalbumin-induced epithelial transport in inflamed guinea pig distal colon.
Topics: Animals; Antigens; Chlorpheniramine; Colitis; Cyclooxygenase Inhibitors; Disease Models, Animal; Epi | 1993 |
Effects of epithelial cell supernatant on membrane potential and contraction of dog airway smooth muscles.
Topics: Animals; Arginine; Bronchi; Cells, Cultured; Dogs; Electrophysiology; Epithelial Cells; Epithelium; | 1994 |
Endothelium-dependent component in the contractile responses of human omental arteries to adrenergic stimulation.
Topics: Adult; Aged; Arginine; Arteries; Electric Stimulation; Endothelium, Vascular; Female; Humans; In Vit | 1993 |
Adenosine induces contractions in suncus ileum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atropine | 1993 |
Cocaine-induced cerebrovasospasm and its possible mechanism of action.
Topics: Animals; Biological Transport; Brain; Calcium; Cells, Cultured; Cocaine; Cyclooxygenase Inhibitors; | 1994 |
Gamma-interferon modifies guinea pig airway functions in vitro.
Topics: Animals; Arginine; Carbachol; Cycloheximide; Guinea Pigs; In Vitro Techniques; Indomethacin; Interfe | 1994 |
Mechanical stimulation of skeletal muscle cells mitigates glucocorticoid-induced decreases in prostaglandin production and prostaglandin synthase activity.
Topics: Animals; Cells, Cultured; Chick Embryo; Dexamethasone; Dinoprost; Dinoprostone; Indomethacin; Kineti | 1994 |
Rat gastric motor response to food protein-induced anaphylaxis.
Topics: Albumins; Anaphylaxis; Animals; Dietary Proteins; Gastrointestinal Motility; Histamine Antagonists; | 1994 |
Potentiation of sensory tachykininergic and parasympathetic cholinergic transmission by epidermal growth factor.
Topics: Acetylcholine; Alprostadil; Animals; Atropine; Capsaicin; Epidermal Growth Factor; Female; Genistein | 1993 |
[In vitro contractility of the musculature of human gallbladders with and without gallstones--relevance of the prostaglandin system for CCK regulated motoricity].
Topics: Adult; Aged; Aged, 80 and over; Cholecystokinin; Cholelithiasis; Culture Techniques; Dose-Response R | 1993 |
Involvement of the "tethered ligand" receptor in thrombin-induced endothelium-mediated relaxations.
Topics: Amino Acid Sequence; Animals; Antithrombins; Arginine; Coronary Vessels; Dogs; Endothelium, Vascular | 1993 |
Characterization of receptor-mediated actions of T-kinin.
Topics: Amino Acid Sequence; Animals; Bradykinin; Dose-Response Relationship, Drug; Female; Indomethacin; Mo | 1993 |
Effect of airway inflammation on smooth muscle shortening and contractility in guinea pig trachealis.
Topics: Aerosols; Animals; Capsaicin; Guinea Pigs; In Vitro Techniques; Indomethacin; Inflammation; Male; Mu | 1993 |
Different modes of endothelin-1 action in pressor response in vivo and pulmonary parenchymal contraction in vitro in the guinea pig.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Pressure; Dose-Re | 1993 |
Dirofilaria immitis: heartworm products contract rat trachea in vitro.
Topics: Acetylcholine; Animals; Aspirin; Culture Techniques; Cyclooxygenase Inhibitors; Dirofilaria immitis; | 1994 |
Endothelium-derived relaxing factor, hypertension and chronic parathyroidectomy in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Acetylcholine; Animals; Aorta; Arginine; Calcium; Cyclic GMP; Drug Interactions; Extracellular Space | 1993 |
Bradykinin contributes to the exercise pressor reflex: mechanism of action.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Gas Analysis; Blood Pressure; Bradykinin; Br | 1993 |
Mechanism of pregnancy-induced attenuation of contraction to phenylephrine in rat aorta.
Topics: Acetylcholine; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Indo | 1993 |
Products of cyclooxygenase mediate the responses of the guinea pig trachea to hydrogen peroxide.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Bridged | 1993 |
Effects of age and indomethacin on response and sensitivity of pulmonary artery to phenylephrine and to histamine in pigs.
Topics: Aging; Animals; Arachidonic Acid; Dogs; Dose-Response Relationship, Drug; Female; Histamine; Indomet | 1993 |
Non-adrenergic, non-cholinergic neural activation in guinea-pig bronchi: powerful and frequency-dependent stabilizing effect on tone.
Topics: Animals; Autonomic Nervous System; Bronchi; Electric Stimulation; Female; Guinea Pigs; Histamine; In | 1993 |
Endothelial modulation of 5-hydroxytryptamine-induced contraction in goat cerebral arteries.
Topics: Animals; Arginine; Cerebral Arteries; Endothelium, Vascular; Epoprostenol; Female; Goats; Gossypol; | 1993 |
Effect of in vitro exposure to acrolein on carbachol responses in rat trachealis muscle.
Topics: Acrolein; Animals; Arachidonic Acid; Carbachol; Dose-Response Relationship, Drug; In Vitro Technique | 1993 |
Contractile effects of nucleotides in guinea pig isolated, perfused trachea: involvement of respiratory epithelium, prostanoids and Na+ and Cl- channels.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo | 1993 |
Influence of hydroxyl radical on rabbit airway smooth muscle chronically exposed to H2O2 in vivo.
Topics: Acetylcholine; Animals; Catalase; Epithelium; Free Radicals; Glucose Oxidase; Histological Technique | 1993 |
Time-dependent improvement in guinea pig tracheal contractility: modification by cyclooxygenase inhibitors.
Topics: Acetylcholine; Adenosine; Animals; Cyclooxygenase Inhibitors; Guinea Pigs; In Vitro Techniques; Indo | 1993 |
Contraction of the rat isolated spleen mediated by adenosine A1 receptor activation.
Topics: Adenosine; Animals; Biotransformation; Corpus Striatum; In Vitro Techniques; Indomethacin; Male; Mus | 1993 |
Characterisation of the peptido-leukotriene receptor PL2 on the ferret spleen strip.
Topics: Animals; Dose-Response Relationship, Drug; Ferrets; In Vitro Techniques; Indomethacin; Leukotriene A | 1993 |
Mediation by the same muscarinic receptor subtype of phasic and tonic contractile activities in the rat isolated portal vein.
Topics: Animals; Arginine; Denervation; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Musca | 1993 |
Motor effects of indomethacin, morphine or vagal nerve stimulation on the feline small intestine in vivo.
Topics: Animals; Aspirin; Autonomic Nervous System; Cats; Diclofenac; Electric Stimulation; Female; Gastroin | 1993 |
Pharmacological modulation of the spasmogenic response to methylxanthines in guinea-pig trachea.
Topics: Animals; Caffeine; Calcium; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indometh | 1993 |
Modification by CO2 of endothelin-1-induced contraction of isolated guinea pig trachea.
Topics: Acetylcholine; Animals; Aspirin; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Interactions | 1993 |
Endothelium-dependent contractions to oxygen-derived free radicals in the canine basilar artery.
Topics: Animals; Arginine; Basilar Artery; Cattle; Dogs; Endothelium, Vascular; Free Radicals; Hydrogen Pero | 1993 |
Mechanism by which indomethacin delays gastric ulcer healing in the rat: inhibited contraction of the ulcer base.
Topics: Acetates; Acetic Acid; Animals; Connective Tissue; Gastric Mucosa; Indomethacin; Male; Muscle Contra | 1993 |
Role of Ca2+ entry in the modulation of airway tone by hypoxia.
Topics: Animals; Bronchi; Calcium; Carbachol; Carbon Dioxide; Dose-Response Relationship, Drug; Hypoxia; Ind | 1993 |
Nonadrenergic, noncholinergic responses stabilize smooth muscle tone, with and without parasympathetic activation, in guinea-pig isolated airways.
Topics: Animals; Atropine; Bronchi; Electric Stimulation; Female; Guanethidine; Guinea Pigs; Indomethacin; M | 1993 |
In vitro and ex vivo inhibitory effects of L- and D-enantiomers of NG-nitro-arginine on endothelium-dependent relaxation of rat aorta.
Topics: Acetylcholine; Animals; Aorta; Arginine; Calcimycin; Endothelium, Vascular; In Vitro Techniques; Ind | 1993 |
Characterization of the angiotensin II-receptor subtype in the longitudinal smooth muscle of the rat portal vein.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Dithiothreitol; In Vitro Techniques; Indo | 1993 |
Partial mediation by nitric oxide of the relaxation of human isolated detrusor strips in response to electrical field stimulation.
Topics: Arginine; Electric Stimulation; Humans; In Vitro Techniques; Indomethacin; Methylene Blue; Muscle Co | 1993 |
Gestational diabetes alters human placental vascular responses to changes in oxygen tension.
Topics: Adolescent; Adult; Arteries; Cell Hypoxia; Diabetes, Gestational; Dose-Response Relationship, Drug; | 1993 |
Endothelium-derived factors modulate contraction of bronchial smooth muscle.
Topics: Animals; Arginine; Bronchi; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; | 1993 |
Antigen-induced contraction of guinea pig isolated pulmonary arteries and lung parenchyma.
Topics: Animals; Antigens; Dicarboxylic Acids; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; M | 1993 |
Prostaglandins mediate the stimulatory effects of endothelin-1 on cAMP accumulation and inositol-1,4,5-trisphosphate production and contraction in cat iris sphincter.
Topics: Adenylyl Cyclases; Animals; Cats; Cattle; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug | 1995 |
Effect of diadenosine phosphates on human umbilical vessels: novel platelet-derived vasoconstrictors.
Topics: Arginine; Blood Platelets; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Enzyme Inhibit | 1995 |
Effects of phorbol 12,13-diacetate and its influence on spasmogenic responses in normal and sensitized guinea-pig trachea.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium; Diuretics; Guinea Pigs; | 1995 |
Endothelin-1 contracts and increases motor responses to ATP in rat seminal vesicle.
Topics: Adenosine Triphosphate; Animals; Endothelins; Indomethacin; Male; Muscle Contraction; Rats; Rats, Wi | 1995 |
Evaluation of vascular actions of the nitric oxide-trapping agent, N-methyl-D-glucamine dithiocarbamate-Fe2+, on basal and agonist-stimulated nitric oxide activity.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Chelating Agents; Electron Spin Resonance Spectro | 1996 |
Evidence that epithelium-derived relaxing factor released by bradykinin in the guinea pig trachea is nitric oxide.
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Bradykinin; Culture Techniques; Cyclic GMP; Cyclooxy | 1996 |
Protein kinase C isoforms in iris sphincter smooth muscle: differential effects of phorbol ester on contraction and cAMP accumulation are species specific.
Topics: Animals; Carcinogens; Cats; Cattle; Cell Membrane; Cyclic AMP; Cyclooxygenase Inhibitors; Cytosol; D | 1996 |
Prejunctional inhibition of cholinergic responses by prostaglandin E2 in human bronchi.
Topics: Acetylcholine; Adult; Atropine; Barium Compounds; Bronchi; Charybdotoxin; Chlorides; Cyclooxygenase | 1996 |
Inhibitory action of 5-hydroxytryptamine on propulsive activity of the guinea-pig isolated colon.
Topics: 5-Methoxytryptamine; Animals; Colon; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniq | 1996 |
Effects of Androctonus crassicauda scorpion venom on endothelium-dependent and -independent vascular responses of rabbit aorta.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Endothelium, Vascu | 1996 |
P2-purinoceptors mediating spasm of the isolated uterus of the non-pregnant guinea-pig.
Topics: Adenosine Triphosphate; Animals; Female; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smoo | 1996 |
Dominant contribution of 5-hydroxytryptamine over thromboxane A2 in contractile response of rabbit isolated aortic preparation to thrombin activated platelets.
Topics: Animals; Aorta; Blood Platelets; Blood Pressure; Female; Indomethacin; Male; Methysergide; Muscle Co | 1995 |
Role of endothelium-derived relaxing factors in arteriolar dilation during muscle contraction elicited by electrical field stimulation.
Topics: Animals; Arginine; Arterioles; Cricetinae; Electric Stimulation; Enzyme Inhibitors; Indomethacin; Mu | 1994 |
Dual regulation of cerebrovascular tone by UTP: P2U receptor-mediated contraction and endothelium-dependent relaxation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; Cattle; Cerebr | 1996 |
Excitatory effects of volatile fatty acids on the in vitro motility of the rumen of sheep.
Topics: Acetylcholine; Animals; Atropine; Butyrates; Butyric Acid; Fatty Acids, Volatile; Female; Gastric Mu | 1996 |
ATP and beta,gamma-methylene ATP produce relaxation of guinea-pig isolated trachealis muscle via actions at P1 purinoceptors.
Topics: Adenosine Triphosphate; Animals; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; | 1996 |
Carbon monoxide-induced relaxation of the ductus arteriosus in the lamb: evidence against the prime role of guanylyl cyclase.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Cyclic GMP; Cyto | 1996 |
Cholinergic-nitrergic interactions in the guinea-pig gastric fundus.
Topics: Acetylcholine; Animals; Arginine; Atropine; Electric Stimulation; Enzyme Inhibitors; Female; Gastric | 1996 |
Hyperglycemia increased the responsiveness of isolated rabbit's pulmonary arterial rings to serotonin.
Topics: Animals; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; In Vitro Techniques; Indomethac | 1996 |
Mediation by prostaglandins of the stimulatory effect of substance P on cyclic AMP production in dog iris sphincter smooth muscle.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Dose-Response | 1996 |
Effects of vasopressin on human renal arteries.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Endothelium, | 1996 |
Mechanism of cooling-induced relaxation in the isolated guinea-pig trachea.
Topics: Animals; Cold Temperature; Guinea Pigs; Hot Temperature; In Vitro Techniques; Indomethacin; Male; Ma | 1996 |
Mechanism of hydroxyl radical-induced modulation of vascular tone.
Topics: Animals; Aorta; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hydroxyl Radical; Indomethacin; | 1997 |
Mn(2+)-induced transient contraction of the longitudinal muscle of guinea-pig stomach through prostaglandin synthesis.
Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Electric Stimulatio | 1996 |
Tyrosine kinase inhibitor-sensitive contractile action of ethanol in gastric smooth muscle: comparison with the action of epidermal growth factor.
Topics: 1-Propanol; Animals; Calcium; Catechols; Cyclohexanones; Enzyme Inhibitors; Epidermal Growth Factor; | 1997 |
Pre- and post-junctional effects of VIP-like peptides in guinea pig tracheal smooth muscle.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; F | 1997 |
Arachidonic acid products-mediated contraction induced by bradykinin in relaxed mesenteric arterial rings from Holtzman rats.
Topics: Animals; Arachidonic Acid; Bradykinin; Bradykinin Receptor Antagonists; Dinoprost; Endothelium, Vasc | 1997 |
Association of gestational diabetes with abnormal maternal vascular endothelial function.
Topics: Acetylcholine; Arginine; Diabetes, Gestational; Endothelium, Vascular; Enzyme Inhibitors; Female; Hu | 1997 |
Hypoxia and response of human umbilical artery strips to 5-hydroxytryptamine: role of prostaglandin F2 alpha.
Topics: Cell Hypoxia; Cyclooxygenase Inhibitors; Dinoprost; Drug Synergism; Enzyme Inhibitors; Humans; In Vi | 1997 |
P1-purinoceptor-mediated vasodilatation and vasoconstriction in hypoxia.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Hypoxia; In Vitro Techniques; In | 1996 |
The role of cyclooxygenase and 5-lipoxygenase metabolites in potentiated endothelin-1-evoked contractions in bovine bronchi.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bronchial Hyperreactivity; Cattle; Cyclooxyg | 1996 |
Effects of baicalein on prostanoid generation from the lung and contractile responses of the trachea in guinea pig.
Topics: Animals; Biological Assay; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinopros | 1997 |
The effects of lithium, indomethacin, and neomycin on vasopressin-induced contractions in rat urinary bladder.
Topics: Animals; Arginine Vasopressin; Indomethacin; Lithium; Male; Muscle Contraction; Muscle, Smooth; Neom | 1997 |
[Effect of shashen maidong decoction on gastric motility in vivo].
Topics: Animals; Drugs, Chinese Herbal; Female; Gastric Emptying; Gastrointestinal Agents; Gastrointestinal | 1996 |
Contractile action of ethanol in guinea pig gastric smooth muscle: inhibition by tyrosine kinase inhibitors and comparison with the contractile action of epidermal growth factor-urogastrone.
Topics: Animals; Calcium; Cyclohexanones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Gro | 1997 |
Apamin-sensitive K+ channels involved in the inhibition of acetylcholine-induced contractions in lamb coronary small arteries.
Topics: Acetylcholine; Animals; Apamin; Arginine; Calcimycin; Calcium; Coronary Vessels; Cyclooxygenase Inhi | 1997 |
Pharmacology and mode of action of bradykinin on mouse-isolated trachea.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Capsaicin; In Vitro Techniques; Indoles; Indom | 1997 |
Role of the endothelium in the relaxation induced by propofol and thiopental in isolated arteries from man.
Topics: Aged; Analysis of Variance; Anesthetics, Intravenous; Cyclooxygenase Inhibitors; Endothelium, Vascul | 1997 |
The comparison of the responsiveness of human isolated internal mammary and gastroepiploic arteries to levcromakalim: an alternative approach to the management of graft spasm.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arteries; Benzopyrans; Coronary | 1997 |
Chronic inhibition of NO synthase enhances the production of prostacyclin in coronary arteries through upregulation of the cyclooxygenase type 1 isoform.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bradykinin; Coronary Vessels; Cyclooxygenase 1; Dogs; Enzyme | 1997 |
Effects of hypercholesterolemia on the contractions to angiotensin II in the isolated aorta and iliac artery of the rabbit: role of arachidonic acid metabolites.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Arachidonic Acid | 1997 |
Endothelium-dependent rhythmic contractions induced by cyclopiazonic acid in rat mesenteric artery.
Topics: Animals; Calcium Channel Blockers; Endothelium, Vascular; Enzyme Inhibitors; Indoles; Indomethacin; | 1997 |
The effect of nitric oxide synthase blockade and indomethacin on gastric emptying and gastric contractility.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Gastric Emptying; In Vitro Tech | 1997 |
Interaction between prostaglandins and selective phosphodiesterase inhibitors in isolated guinea-pig trachea in vitro.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Drug Interactions; Female; Guanidines; | 1997 |
EP1 receptor blockade attenuates both spontaneous tone and PGE2-elicited contraction in guinea pig trachealis.
Topics: Acetylcholine; Animals; Biphenyl Compounds; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chl | 1997 |
Regional differentiation in the rat aorta: effects of cyclooxygenase inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; Aorta, Abdominal; Aorta, Thoracic; Aspir | 1997 |
Functional characterization of receptors for cysteinyl-leukotrienes in sheep trachealis muscle.
Topics: Animals; Cyclooxygenase Inhibitors; Epithelium; Female; In Vitro Techniques; Indomethacin; Male; Mus | 1997 |
The signalling pathway which causes contraction via P2-purinoceptors in rat urinary bladder smooth muscle.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Carbamates; Estrenes; In Vitro Tech | 1997 |
Endothelin receptor-mediated Ca2+ mobilization and contraction in bovine oviductal arteries: comparison with noradrenaline and potassium.
Topics: Animals; Cadmium; Caffeine; Calcium; Calcium Channel Agonists; Cattle; Endothelin Receptor Antagonis | 1997 |
Neurokinin A increases duodenal mucosal permeability, bicarbonate secretion, and fluid output in the rat.
Topics: Animals; Bicarbonates; Chromium Radioisotopes; Duodenum; Edetic Acid; Gastrointestinal Motility; Hex | 1997 |
Prostaglandins reduce the contractile responses to noradrenaline and angiotensin II in canine femoral arteries after but not before chronic inhibition of nitric oxide synthesis.
Topics: Angiotensin II; Animals; Blood Pressure; Cyclooxygenase Inhibitors; Dogs; Endothelium, Vascular; Fem | 1997 |
Airway smooth muscle, tidal stretches, and dynamically determined contractile states.
Topics: Animals; Biomechanical Phenomena; Cattle; Cyclooxygenase Inhibitors; Elasticity; In Vitro Techniques | 1997 |
Enhanced endothelial nitric oxide activity contributes to the reduced responsiveness of vascular alpha1-adrenoceptors following aortic barodenervation.
Topics: Animals; Aorta; Cyclooxygenase Inhibitors; Denervation; Endothelium, Vascular; Enzyme Inhibitors; He | 1997 |
Myogenic and neurogenic mechanisms and arachidonate metabolites in bronchial muscle response to allergen.
Topics: Allergens; Animals; Arachidonic Acids; Ascaris suum; Bronchi; Bronchial Hyperreactivity; Carbachol; | 1997 |
Pharmacological characterization of the contractile effects of galanin (1-29)-NH2, galantide and galanin (1-14)-(alpha-aminobutyric acid8)scyliorhinin-I in the rat gastric fundus.
Topics: Acetylcholine; Analgesics; Animals; Calcium Channels; Dose-Response Relationship, Drug; Female; Gala | 1997 |
Biphasic response to bradykinin in isolated porcine iliac arteries is mediated by bradykinin B1 and B2 receptors.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin | 1998 |
Effect of serum on vascular smooth muscle function.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood; Cattle; Corticosterone; Cyclooxygenase Inhi | 1998 |
Contractile responses of proximal and distal trachea segments isolated from rats subjected to immunological stimulation: role of connective tissue mast cells.
Topics: Anaphylaxis; Animals; Anti-Asthmatic Agents; Cromolyn Sodium; Cyclooxygenase Inhibitors; Indomethaci | 1998 |
Early effects of acute gamma-radiation on vascular arterial tone.
Topics: Animals; Antioxidants; Aorta, Thoracic; Female; Free Radical Scavengers; Free Radicals; Gamma Rays; | 1998 |
Regulation of ductus arteriosus patency by nitric oxide in fetal lambs: the role of gestation, oxygen tension, and vasa vasorum.
Topics: Aminoquinolines; Animals; Aorta; Calcimycin; Ductus Arteriosus; Ductus Arteriosus, Patent; Enzyme In | 1998 |
Involvement of thromboxane A2 in the mediation of the contractile effect induced by inhibition of nitric oxide synthesis in isolated rat middle cerebral arteries.
Topics: Animals; Cerebral Arteries; Cyclooxygenase Inhibitors; Dioxanes; Enzyme Inhibitors; Indomethacin; Ma | 1998 |
Rat aorta and mesenteric artery respond differently to serotonin.
Topics: Animals; Aorta; Captopril; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteri | 1997 |
Effects of the selective cyclooxygenase-2 inhibitor nimesulide on vascular contractions in endothelium-denuded rat aorta.
Topics: Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Clonidine; Cyclooxygenase 2; Cyclooxygenase | 1998 |
In vitro evidence that rabbit distal colonic muscularis mucosae has a Clostridium difficile toxin A receptor.
Topics: Acetylcholine; Analysis of Variance; Animals; Bacterial Toxins; Clostridioides difficile; Colon; Ent | 1998 |
Role of nitric oxide in in vitro contractile activity of the third compartment of the stomach in llamas.
Topics: Animals; Apamin; Atropine; Camelids, New World; Electric Stimulation; Enzyme Inhibitors; Guanethidin | 1998 |
Endothelium-derived prostanoids reduce 5-hydroxytryptamine-induced contraction in the human uterine artery.
Topics: Adult; Aged; Arteries; Cyclooxygenase Inhibitors; Drug Synergism; Endothelium, Vascular; Enzyme Inhi | 1998 |
Pharmacologic characterization of latex extracts by isolated guinea pig tracheal tissue.
Topics: Animals; Arachidonic Acids; Atropine; Capsaicin; Cholinergic Antagonists; Cyclooxygenase Inhibitors; | 1998 |
Purification, characterization, and spasmogenic activity of neurotensin from the toad Bufo marinus.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Atropine; Bufo marinus; Cattle; Chromatography, High Pr | 1998 |
Biphasic relaxant response of ovine trachealis muscle to electrical field stimulation: influence of cooling.
Topics: Analysis of Variance; Animals; Atropine; Capsaicin; Carbachol; Cold Temperature; Electric Stimulatio | 1999 |
Effect of interleukin-1beta on the ascending and descending reflex in rat small intestine.
Topics: Animals; Cyclooxygenase Inhibitors; Electric Stimulation; Histamine Antagonists; Imidazoles; In Vitr | 1998 |
Responses of umbilical arteries and veins to diverse vasoactives drugs.
Topics: Acetylcholine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Indomethacin; Infant, Ne | 1998 |
Chronic blockade of endothelin ETA receptors improves flow dependent dilation in resistance arteries of hypertensive rats.
Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelin Rece | 1998 |
Mechanisms and sites of action of endothelins 1 and 2 on the opossum internal anal sphincter smooth muscle tone in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic Agents; Anal Canal; Animals; Atropine; Cal | 1999 |
Analysis of an H1 receptor-mediated, zinc-potentiated vasoconstrictor action of the histidyl dipeptide carnosine in rabbit saphenous vein.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carnosine; Cimetidine; Drug Interactions; Histamin | 1998 |
Contractile responses elicited by hydrogen peroxide in aorta from normotensive and hypertensive rats. Endothelial modulation and mechanism involved.
Topics: Animals; Aorta; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Dimethyl Sulfoxide; Endothe | 1998 |
Potentiation of bradykinin-induced responses by indomethacin in the intact and denuded epithelium of guinea pig tracheal preparations.
Topics: Animals; Bradykinin; Drug Synergism; Epithelium; Female; Guinea Pigs; In Vitro Techniques; Indometha | 1998 |
Effects of cell-permeant calcium chelators on contractility in monkey basilar artery.
Topics: Animals; Basilar Artery; Caffeine; Calcium; Chelating Agents; Dinoprost; Dogs; Egtazic Acid; Endothe | 1999 |
Streptozotocin diabetes in the pregnant rat induces cardiovascular dysfunction in adult offspring.
Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Cardiovascular Diseases; Diabetes Mellitus, Expe | 1999 |
Evaluation of possible mechanism of anti-ulcerogenic activity of UL-409, a herbal preparation.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Aspirin; Carbohydrates; Cyclooxygenase Inhibitors; | 1998 |
The cyclo-oxygenase-dependent regulation of rabbit vein contraction: evidence for a prostaglandin E2-mediated relaxation.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; Arachidonic Acid; Bi | 1999 |
Enhanced, unaltered and impaired nitric oxide-mediated endothelium-dependent relaxation in experimental diabetes mellitus: importance of disease duration.
Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibi | 1999 |
Relative roles of cyclooxygenase and nitric oxide synthase pathways in ischemia-induced increased contraction of cavernosal smooth muscle.
Topics: Animals; Arginine; Arteriosclerosis; Electric Stimulation; Enzyme Inhibitors; Hypercholesterolemia; | 1999 |
Long-term treatment with fluoxetine associates with peripheral effects on rat vas deferens contractility.
Topics: Adrenergic Agents; Animals; Antidepressive Agents, Second-Generation; Binding Sites; Calcium; Cycloo | 1999 |
Vasoactive substances produced by cultured rat brain endothelial cells.
Topics: Animals; Arachidonic Acid; Brain; Cell Line; Cells, Cultured; Coronary Vessels; Culture Media, Condi | 1999 |
Age-related changes in adenosine 5'-triphosphate-induced constriction of isolated, perfused mesenteric arteries of rats.
Topics: Adenosine Triphosphate; Aging; Animals; Blood Pressure; Endothelium, Vascular; In Vitro Techniques; | 1999 |
Cyclosporine A preparations and their vehicles induce contraction of the guinea pig gallbladder in vitro: the role of cyclooxygenase metabolites.
Topics: Acetylcholine; Administration, Oral; Animals; Cyclooxygenase Inhibitors; Cyclosporine; Enzyme Inhibi | 1999 |
Cyclic pentapeptides of chiral sequence DLDDL as scaffold for antagonism of G-protein coupled receptors: synthesis, activity and conformational analysis by NMR and molecular dynamics of ITF 1565 a substance P inhibitor.
Topics: Animals; Aorta; GTP-Binding Proteins; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagen | 1999 |
Time-course of the alterations in prostanoid production and in contractile responses of mesenteric beds isolated from streptozotocin diabetic rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Diabetes Mellitus, Experimental; Dinoprost; Dinoprostone; Ind | 1999 |
Increased activity of H2O2 in aorta isolated from chronically streptozotocin-diabetic rats: effects of antioxidant enzymes and enzymes inhibitors.
Topics: Amitrole; Animals; Antioxidants; Aorta; Catalase; Cyclooxygenase Inhibitors; Diabetes Mellitus, Expe | 1999 |
In vitro effects of nonsteroidal anti-inflammatory agents and prostaglandins I2, E2, and F2alpha on contractility of taenia of the large colon of horses.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Clonixin; Colon; Cyclooxygenase Inhibi | 1999 |
Cannabinoid inhibition of guinea-pig intestinal peristalsis via inhibition of excitatory and activation of inhibitory neural pathways.
Topics: Animals; Arachidonic Acids; Cannabinoids; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indometha | 1999 |
Pharmacological effects of Agapanthus africanus on the isolated rat uterus.
Topics: Acetylcholine; Animals; Atropine; Diethylstilbestrol; Dose-Response Relationship, Drug; Female; In V | 1999 |
Pharmacological characterization of metamizol-induced relaxation in phenylephrine-precontracted rabbit thoracic aorta smooth muscle.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Dipyrone; Dose-Response Relations | 1999 |
Vasodilator action in the nitroxylated cyanoamidine derivative, KRN2391, in rabbit basilar artery.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Basilar Artery; Cyclic AMP; Cyclic GMP; Cyclooxygenase | 1999 |
Biological evaluation of the nitric oxide-trapping agent, N-methyl-D-glucamine dithiocarbamate-Fe2+, as a probe of nitric oxide activity released from control and diabetic rat endothelium.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Chelating Agents; Diabetes Mell | 1999 |
Pharmacological and molecular evidence for kinin B1 receptor expression in urinary bladder of cyclophosphamide-treated rats.
Topics: Acrolein; Animals; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Cyclophos | 1999 |
Interleukin-1beta-induced hyperresponsiveness to [Sar9,Met(O2)11]substance P in isolated human bronchi.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Anti-Inflammatory Agents, | 1999 |
Interleukin-1beta-induced hyperresponsiveness to [Sar9,Met(O2)11]substance P in isolated human bronchi.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Anti-Inflammatory Agents, | 1999 |
Interleukin-1beta-induced hyperresponsiveness to [Sar9,Met(O2)11]substance P in isolated human bronchi.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Anti-Inflammatory Agents, | 1999 |
Interleukin-1beta-induced hyperresponsiveness to [Sar9,Met(O2)11]substance P in isolated human bronchi.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Anti-Inflammatory Agents, | 1999 |
Response to isoprenaline of rabbit detrusor muscle following exposure to 5, 8, 11, 14 eicosatetraynoic acid. Role of prostanoids on beta-adrenergic-evoked response.
Topics: Alprostadil; Animals; Arachidonic Acids; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; | 1999 |
A pharmacological examination of venom from the Papuan taipan (Oxyuranus scutellatus canni).
Topics: Acetophenones; Acetylcholine; Animals; Aorta; Blood Pressure; Carbachol; Chickens; Diaphragm; Dose-R | 1999 |
Threshold concentrations of endothelin-1: the effects on contractions induced by 5-hydroxytryptamine in isolated rat cerebral and mesenteric arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Basilar Artery; Bipheny | 1999 |
Antagonistic effects of losartan on thromboxane A2-receptors in human isolated gastroepiploic artery and saphenous vein.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Angiotensin Rece | 1999 |
Intestinal motor depression by 7-nitroindazole through an action unrelated to nitric oxide synthase inhibition.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gastrointestinal Motility; Gui | 1999 |
Cholinergic contraction is altered in nNOS knockouts. Cooperative modulation of neural bronchoconstriction by nNOS and COX.
Topics: Animals; Atropine; Bronchi; Bronchoconstriction; Cholinergic Fibers; Cyclooxygenase Inhibitors; Elec | 1999 |
Effects of the chronic in vivo administration of L-NAME on the contractile responses of the rat perfused mesenteric bed.
Topics: Animals; Blood Pressure; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhib | 1999 |
Chronic exposure to hypoxia attenuates contractile responses in rat airways in vitro: a possible role for nitric oxide.
Topics: Albuterol; Animals; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Cyclooxygenase Inhibi | 1999 |
Pranidipine enhances relaxation produced by endothelium-derived relaxing factor in carotid artery.
Topics: Acetylcholine; Animals; Calcium Channel Blockers; Carotid Arteries; Dihydropyridines; Dose-Response | 1999 |
Selective cyclooxygenase-2 inhibitors reduce ureteral contraction in vitro: a better alternative for renal colic?
Topics: Animals; Colic; Cyclooxygenase Inhibitors; Dimethyl Sulfoxide; Humans; In Vitro Techniques; Indometh | 2000 |
Effects of selective inhibitors of cyclo-oxygenase-1 (COX-1) and cyclo-oxygenase-2 (COX-2) on the spontaneous myogenic contractions in the upper urinary tract of the guinea-pig and rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase | 2000 |
Simulated microgravity-induced vascular hyporesponsiveness: role of signal transduction.
Topics: Animals; Aorta, Abdominal; Cyclooxygenase Inhibitors; Hindlimb Suspension; In Vitro Techniques; Indo | 1999 |
Endogenous prostaglandin formation in the field-stimulated guinea-pig vas deferens: comparison of the inhibitory effects of indomethacin and NS-398.
Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Dinoprostone; Electric Stimulation; Guinea Pig | 1999 |
Effects of neutral sphingomyelinase on phenylephrine-induced vasoconstriction and Ca(2+) mobilization in rat aortic smooth muscle.
Topics: Animals; Aorta, Thoracic; Calcium; Cells, Cultured; Ceramides; Cyclooxygenase Inhibitors; Endotheliu | 2000 |
Spontaneous contractions in elasmobranch vessels in vitro.
Topics: Animals; Aorta; Cell Hypoxia; Epinephrine; Indomethacin; Liver Circulation; Muscle Contraction; Musc | 2000 |
Mechanisms of the contractile effect of the hydroalcoholic extract of Cissampelos sympodialis Eichl. in the rat aorta.
Topics: Adrenergic alpha-Antagonists; Alcohols; Animals; Aorta; Cyclooxygenase Inhibitors; Dose-Response Rel | 2000 |
Actions of angiotensin peptides on the rabbit pulmonary artery.
Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Angiotensins; Animals; Cyclooxyge | 2000 |
Endothelium and aortic contraction to endothelin-1 in the pregnant rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Blood Pressure; Body Weight; Endo | 2000 |
Nitric oxide prevents rat duodenal contractions induced by potentially noxious agents.
Topics: Animals; Arginine; Bicarbonates; Capsaicin; Carbon Dioxide; Chromium Radioisotopes; Crosses, Genetic | 2000 |
Tissue hypoxia inhibits prostaglandin and nitric oxide production and prevents ductus arteriosus reopening.
Topics: Animals; Animals, Newborn; Cell Hypoxia; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Rela | 2000 |
5-hydroxytryptamine induces vasoconstriction of the human umbilical artery: effects of hypoxia and nicorandil.
Topics: Humans; Hypoxia; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Ni | 2000 |
Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder.
Topics: Animals; Caenorhabditis elegans Proteins; Dose-Response Relationship, Drug; Gallbladder; Guinea Pigs | 2000 |
Subrenal aorta coarctation of pregnant rats: changes in vascular contractility.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Aortic Coarctation; Dose-Response | 2000 |
Influences of indomethacin on contractions induced by endothelins in guinea pig isolated gallbladder.
Topics: Animals; Endothelins; Female; Gallbladder; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Mus | 2000 |
Function of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the ductus arteriosus from foetal lamb: differential development and change by oxygen and endotoxin.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; | 2001 |
Contractile actions of proteinase-activated receptor-derived polypeptides in guinea-pig gastric and lung parenchymal strips: evidence for distinct receptor systems.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Antibodies, Blocking; Guinea Pigs; Immunohistoc | 2001 |
Effect of indomethacin on gallbladder inflammation and contractility during acute cholecystitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholecystitis; Common Bile Duct; Ga | 2001 |
Antinociceptive properties of N-aryl-glutaramic acids and N-aryl-glutarimides.
Topics: Acetic Acid; Analgesics; Aspirin; Chromatography, Thin Layer; Formaldehyde; Glutamic Acid; Humans; I | 2000 |
The involvement of phospholipase A(2) in ethanol-induced gastric muscle contraction.
Topics: Animals; Cats; Central Nervous System Depressants; Cyclooxygenase Inhibitors; Dose-Response Relation | 2001 |
Endothelin-1 releases endothelium-derived endoperoxides and thromboxane A2 in porcine coronary arteries with regenerated endothelium.
Topics: Animals; Coronary Vessels; Cyclooxygenase Inhibitors; Endothelin-1; Endothelium, Vascular; Imidazole | 1999 |
Tachykinin NK(2) receptor mediates contraction and ion transport in rat colon by different mechanisms.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colon; Indomethacin; Intestinal Mucosa; Ion Transp | 2001 |
In utero remodeling of the fetal lamb ductus arteriosus: the role of antenatal indomethacin and avascular zone thickness on vasa vasorum proliferation, neointima formation, and cell death.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blotting, Western; Cell Death; Cell Division; Coronary Circul | 2001 |
Endothelial factors involved in the bradykinin-induced relaxation of the guinea-pig aorta.
Topics: Animals; Aorta, Thoracic; Bradykinin; Carbenoxolone; Endothelium, Vascular; Gap Junctions; Guinea Pi | 2000 |
Isoprostaglandin E2 type-III (8-iso-prostaglandin E2) evoked contractions in the human internal mammary artery.
Topics: Aged; Biphenyl Compounds; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; F2-Isoprostanes | 2001 |
The effect of vitamin A on contraction of the ductus arteriosus in fetal rat.
Topics: Animals; Calcium; Ductus Arteriosus; Endothelium, Vascular; Female; Fetus; Indomethacin; Maternal-Fe | 2001 |
Effect of progesterone on the contractile response of isolated pulmonary artery in rabbits.
Topics: Animals; Calcium; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Muscle | 2001 |
The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound.
Topics: Acetylcholine; Animals; Benzofurans; Binding, Competitive; Carbachol; Cell Line; CHO Cells; Colon; C | 2001 |
Simulated microgravity upregulates an endothelial vasoconstrictor prostaglandin.
Topics: Analysis of Variance; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carotid Arteries; Cyclooxyge | 2001 |
Impaired relaxation to acetylcholine in 2K-1C hypertensive rat aortas involves changes in membrane hyperpolarization instead of an abnormal contribution of endothelial factors.
Topics: Acetylcholine; Animals; Aorta; Biological Factors; Cyclic GMP; Disease Models, Animal; Endothelium, | 2000 |
A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Bronchi; Calcium Channel Blockers; Caps | 2001 |
Evidence for the presence of A(1) adenosine receptors in the aorta of spontaneously hypertensive rats.
Topics: Adenine; Adenosine; Animals; Aorta; Culture Techniques; Dose-Response Relationship, Drug; Endotheliu | 2001 |
Receptor preferences of cysteinyl-leukotrienes in the guinea pig lung parenchyma.
Topics: Animals; Bronchodilator Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme | 2002 |
Comparative study of the contractile activity evoked by ATP and diadenosine tetraphosphate in isolated rat urinary bladder.
Topics: Adenosine Triphosphate; Animals; Atropine; Dinucleoside Phosphates; Dose-Response Relationship, Drug | 2002 |
Inhibitory actions of indomethacin on electrical and mechanical responses produced by nerve stimulation in circular smooth muscle of the guinea-pig gastric fundus.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Calcium C | 2001 |
Contractile responses in spontaneously diabetic mice. I. Involvement of superoxide anion in enhanced contractile response of aorta to norepinephrine in C57BL/KsJ(db/db) mice.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Blood Glucose; Bod | 2000 |
Relaxation of guinea pig trachealis during electrical field stimulation increases with age.
Topics: Aging; Animals; Bronchoconstriction; Cyclooxygenase Inhibitors; Electric Stimulation; Guinea Pigs; I | 2002 |
Muscarinic receptor knockout mice: role of muscarinic acetylcholine receptors M(2), M(3), and M(4) in carbamylcholine-induced gallbladder contractility.
Topics: Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Cardiovascular Agents; Cholinesterase Inhibito | 2002 |
Constitutive expression and function of cyclooxygenase-2 in murine gastric muscles.
Topics: Acetylcholine; Animals; Cyclooxygenase 2; Female; Immunohistochemistry; Indomethacin; Isoenzymes; Ma | 2002 |
Bacterial toxin N-formyl-methionyl-leucyl-phenylalanine acutely contracts human and rabbit detrusor through the release of eicosanoids.
Topics: Animals; Bacterial Toxins; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; | 2002 |
Sensitization of enteric reflexes in the rat colon in vitro.
Topics: Animals; Area Under Curve; Carbachol; Cholinergic Agonists; Colon; Cyclooxygenase Inhibitors; Dose-R | 2002 |
Simultaneous changes in intracellular calcium and tension induced by endothelin-1 and sarafotoxin S6c in guinea pig isolated gallbladder: influence of indomethacin.
Topics: Animals; Calcium; Endothelin-1; Female; Gallbladder; Guinea Pigs; In Vitro Techniques; Indomethacin; | 2002 |
Effects of endotoxin-induced shock on withdrawal contractions in the Guinea-pig isolated ileum.
Topics: Animals; Endotoxins; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Morphine; | 2002 |
Differential responsiveness of proximal and distal parts of isolated guinea pig trachea.
Topics: Animals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelium; | 2002 |
Effect of inflammatory mediators on the physiology of the human Fallopian tube.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Diclofenac; Dose-Response Relatio | 2002 |
Effects of aminophylline, imidazole and indomethacin on spontaneous and prostaglandin induced ovarian contractions in vitro.
Topics: Aminophylline; Animals; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Muscle C | 1975 |
Possible involvement of prostaglandins in the contractile action of bradykinin on rat terminal ileum.
Topics: Animals; Aspirin; Bradykinin; Ileum; Indomethacin; Male; Muscle Contraction; Prostaglandins; Rats | 1976 |
Mediation of prostaglandin E2 in the biphasic response to ATP of the isolated tracheal muscle of guinea-pigs.
Topics: Adenosine Triphosphate; Animals; Aspirin; Drug Interactions; Guinea Pigs; In Vitro Techniques; Indom | 1976 |
Possible mechanisms involved in the coronary vasodilatory response to dopamine.
Topics: Adrenergic alpha-Antagonists; Animals; Coronary Circulation; Coronary Vessels; Dogs; Dopamine; Femal | 1976 |
Pharmacological differences of non-adrenergic inhibitory response and of ATP-induced relaxation in guineq-pig tracheal strip-chains.
Topics: Adenosine Triphosphate; Animals; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Muscle Relaxat | 1976 |
Antagonism of arachidonic acid hydroperoxide on isolated gastrointestinal tissues as a measure of the inhibition of prostaglandin biosynthesis.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Biolog | 1976 |
Specific desensitization (tachyphylaxis) of the guinea pig ileum to angiotensin II.
Topics: Angiotensin II; Animals; Binding Sites; Bradykinin; Calcium; Dose-Response Relationship, Drug; Gluco | 1977 |
Bradykinin relaxes contracted airways through prostaglandin production.
Topics: Animals; Bradykinin; Bronchi; Dogs; Guinea Pigs; In Vitro Techniques; Indomethacin; Muscle Contracti | 1977 |
Atypical (relaxant) response to histamine in cat bronchus.
Topics: Airway Resistance; Animals; Bronchi; Burimamide; Carbachol; Cats; Female; Histamine; Histamine H1 An | 1977 |
Effects of aspirin-like drugs on canine gastric mucosal blood flow and acid secretion.
Topics: Acetaminophen; Animals; Aspirin; Dogs; Female; Gastric Mucosa; Indomethacin; Muscle Contraction; Mus | 1977 |
Responses of rabbit portal vein to histamine.
Topics: Animals; Atropine; Drug Interactions; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; | 1978 |
The effect of neurotransmitters, bradikynin, prostaglandins, and follicular fluid on spontaneous contractile characteristics of human fimbriae and tubo-ovarian ligaments isolated during different stages of the sexual cycle.
Topics: Body Fluids; Bradykinin; Fallopian Tubes; Female; Humans; Indomethacin; Ligaments; Menstruation; Mus | 1978 |
In vitro spontaneous and norepinephrine-induced contractions of ampulla, isthmus, and mesosalpinx from human fallopian tubes; effects of cocaine and indomethacin.
Topics: Cocaine; Drug Interactions; Fallopian Tubes; Female; Humans; Indomethacin; Middle Aged; Muscle Contr | 1978 |
Slow-reacting substance of anaphylaxis: studies on purification and characterisation.
Topics: Animals; Arachidonic Acids; Autacoids; Bronchi; Fatty Acids; Guinea Pigs; Humans; Ileum; Indomethaci | 1979 |
Letter: Prostaglandins and asthma.
Topics: Antigens; Asthma; Humans; Indomethacin; Muscle Contraction; Muscles; Physical Exertion; Prostaglandi | 1975 |
Letter: Prostaglandins and asthma.
Topics: Animals; Asthma; Guinea Pigs; Humans; Indomethacin; Muscle Contraction; Prostaglandins; Spirometry; | 1975 |
In vitro action of combined salbutamol and theophylline on anaphylactic contractions, mediator release and cyclic 3',5'-adenosine monophosphate in lung parenchyma.
Topics: Albuterol; Anaphylaxis; Animals; Cyclic AMP; Guinea Pigs; Histamine Release; In Vitro Techniques; In | 1979 |
Studies in vitro on the effect of adenosine, adenine and NAD on guinea pig myometrium in the presence of exogenously applied PGE2.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; | 1979 |
The influence of prostaglandin synthetase inhibition on the spontaneous contractile activity and induced responses of the human oviduct.
Topics: Adult; Cyclooxygenase Inhibitors; Fallopian Tubes; Female; Humans; Indomethacin; Muscle Contraction; | 1979 |
Reversible depression of electrically-induced contractions of guinea pig longitudinal muscle by a reversible inhibitor of prostaglandin synthetase.
Topics: Amidines; Animals; Chlorphenamidine; Clonidine; Cyclooxygenase Inhibitors; Guinea Pigs; Indomethacin | 1979 |
The effect of caesium on adrenergic transmission in rabbit vas deferens.
Topics: Action Potentials; Animals; Cesium; Electric Stimulation; Guanethidine; In Vitro Techniques; Indomet | 1975 |
[Physiological role of prostaglandins in adrenergic and non-adrenergic inhibitory neurotransmission in guinea pig taenia coli].
Topics: Animals; Colon; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; | 1975 |
Evidence for a role of prostaglandins in atropine-resistant transmission in the mammalian urinary bladder.
Topics: Animals; Atropine; Drug Interactions; Drug Resistance; Female; Haplorhini; Indomethacin; Macaca fasc | 1976 |
A comparison of the effects of angiotensin II and heptapeptide on smooth muscle (vascular and uterine).
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dose-Response Relationship, Drug; | 1976 |
Block of electrically induced contractions of guinea pig longitudinal muscle by prostaglandin synthetase and receptor inhibitors.
Topics: Acetylcholine; Animals; Arachidonic Acids; Electric Stimulation; Guinea Pigs; Ileum; Indomethacin; M | 1976 |
Effects of urotensin I on isolated blood vessels.
Topics: Acetylcholine; Animals; Atropine; Blood Vessels; Cyclic AMP; Drug Interactions; In Vitro Techniques; | 1976 |
Interrelations between cyclic AMP, cyclic GMP and contraction in guinea pig gallbladder stimulated by cholecystokinin.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cholecystokinin; Cyclic AMP; Cyclic GMP; Female; Gallb | 1977 |
Presynaptic inhibitory actions of adenine nucleotides and adenosine on neurotransmission in the rat vas deferens.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Atropine; Depression, Chemical; Dip | 1977 |
Effects of urotensin I on the isolated rat tail artery: possible mediation of the relaxation responses by cAMP.
Topics: Animals; Arteries; Cyclic AMP; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle R | 1978 |
Interaction of prostaglandins and adenosine 5'-triphosphate in the noncholinergic neurotransmission in rabbit detrusor.
Topics: Adenosine Triphosphate; Animals; Carbachol; Dose-Response Relationship, Drug; Drug Interactions; Fem | 1978 |
Effects of prostaglandins on excitatory transmission in isolated canine tracheal muscle.
Topics: Acetylcholine; Animals; Depression, Chemical; Dogs; Electric Stimulation; Female; In Vitro Technique | 1978 |
The direct influence of thyrotropin-releasing hormone (TRH) on the smooth muscle of rat duodenum.
Topics: Animals; Bucladesine; Duodenum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle | 1979 |
An electrophysiological analysis of the actions of prostaglandin on neuromuscular transmission in the guinea-pig vas deferens.
Topics: Action Potentials; Animals; Calcium; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Membrane | 1979 |
The treatment of threatened premature labor by tocolytics, Ca++-Antagonists and anti-inflammatory drugs.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Aspirin; Calcium; Drug Therapy, Combina | 1975 |
Generation of prostaglandin E-like material by the guinea-pig trachea contracted by histamine.
Topics: Animals; Colon; Histamine; In Vitro Techniques; Indomethacin; Isoproterenol; Mice; Muscle Contractio | 1975 |
Application of drug receptor theories to the analysis of the myotropic effects of bradykinin.
Topics: Animals; Bradykinin; Cats; Dose-Response Relationship, Drug; Duodenum; Female; Histamine H1 Antagoni | 1975 |
Release of slow reacting substance (SRS) from rat basophilic leukemia (RBL-1) cells.
Topics: Animals; Anti-Bacterial Agents; Arylsulfatases; Basophils; Benzopyrans; Calcimycin; Cells, Cultured; | 1977 |
Microsomal preparations of normal bovine iris-ciliary body generate prostacyclin-like but not thromboxane-A2-activity.
Topics: Animals; Arteries; Cattle; Ciliary Body; Dogs; Epoprostenol; Humans; Indomethacin; Iris; Microsomes; | 1977 |
PGE2 is a more potent vasodilator of the lamb ductus arteriosus than is either PGI2 or 6 keto PGF1alpha.
Topics: Animals; Ductus Arteriosus; Epoprostenol; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscl | 1978 |
Potentiation of PG effects on the intraocular muscles of the cat by inhibition of PG synthesis.
Topics: Animals; Cats; Ciliary Body; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Syner | 1977 |
Prostaglandin and histaminergic mediation of prolonged vasodilation after exercise.
Topics: Animals; Cyclooxygenase Inhibitors; Dogs; Electric Stimulation; Fatigue; Hindlimb; Histamine; Indome | 1977 |
Endogenous prostaglandin E and contractile activity of isolated ileal smooth muscle.
Topics: Acetylcholine; Animals; Cats; Cyclooxygenase Inhibitors; Drug Interactions; Ileum; In Vitro Techniqu | 1978 |
Effects of indomethacin on labor, fetal oxygenation, and fetal development in rhesus monkeys.
Topics: Amniotic Fluid; Animals; Female; Fetus; Gestational Age; Haplorhini; Indomethacin; Labor, Obstetric; | 1978 |
Prostaglandins and tetrodotoxin-insensitive relaxation of opossum lower esophageal sphincter.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Action Potentials; Animals; Black Widow Spider; Carbachol; Esophago | 1979 |
Anaphylaxis in guinea-pig peripheral airways in vitro.
Topics: Anaphylaxis; Animals; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Isoproteren | 1979 |
Effects of neuronal polypeptides on intestinal smooth muscle; a comparison with non-adrenergic, non-cholinergic nerve stimulation and ATP.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Enkephalins; Female; Guinea Pigs; In Vitro Te | 1979 |
Inhibition of ATP-induced contraction in the guinea-pig urinary bladder in vitro and in vivo.
Topics: Adenosine; Adenosine Triphosphate; Amines; Animals; Female; Guinea Pigs; Indomethacin; Isoproterenol | 1979 |
Prostaglandin E release from dog skeletal muscle during restricted flow exercise.
Topics: Animals; Dogs; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscles; Prostaglandins E; Vas | 1979 |
[Studies on the mechanism of the effect of adenosine on the contractility of blood vessels on human placenta].
Topics: Adenosine; Adenosine Triphosphate; Drug Antagonism; Female; Humans; Indomethacin; Muscle Contraction | 1979 |
Effects of prostaglandin E2 and indomethacin on the rebound of the guinea-pig taenia coli.
Topics: Animals; Colon; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; | 1979 |
Responses of isolated human internal anal sphincter to drugs and electrical field stimulation.
Topics: Adenosine Triphosphate; Anal Canal; Ascorbic Acid; Autonomic Agents; Electric Stimulation; Humans; I | 1979 |
Effect of prostaglandin E1 and indomethacin on responses of longitudinal muscle of guinea-pig ileum to cholecystokinin.
Topics: Acetylcholine; Animals; Cecum; Cholecystokinin; Clonidine; Electric Stimulation; Female; Guinea Pigs | 1979 |
The effect of varying the concentration of calcium ions on the actions of indomethacin and PGE1 in guinea-pig ileum.
Topics: Animals; Calcium; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle Con | 1979 |
Possible involvement of prostaglandins in the action of ATP on guinea-pig uterus.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Arachidonic Acids; F | 1979 |
Pharmacological evaluation of the lung strip of neonatal swine.
Topics: Animals; Animals, Newborn; Carbachol; Female; Histamine; Indomethacin; Isoproterenol; Lung; Male; Mu | 1979 |
Non-specific antagonism against thromboxane A2 of 7-ethoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1(2H)-phthalazinone (EG-626) in contraction of isolated smooth muscles.
Topics: Angiotensin II; Animals; Aorta; Imidazoles; Indomethacin; Muscle Contraction; Muscle, Smooth; Prosta | 1979 |
Prostaglandins and the contractile action of bradykinin on the longitudinal muscle of rat isolated ileum.
Topics: Animals; Aspirin; Bradykinin; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Mu | 1979 |
Experimental investigation on the pathogenesis of tartrazine-induced asthma.
Topics: Animals; Asthma; Azo Compounds; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Synerg | 1979 |
Post-tetanic potentiation in the innervated smooth muscle preparation of the guinea-pig ileum.
Topics: Acetylcholine; Animals; Guinea Pigs; Ileum; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; | 1979 |
Effect of indoprofen on prostaglandin and thromboxane A2 synthesis in the guinea pig lung.
Topics: Animals; Arachidonic Acids; Depression, Chemical; Female; Guinea Pigs; In Vitro Techniques; Indometh | 1979 |
The contribution of prostaglandins in the muscle of human isolated small intestine to neurogenic responses.
Topics: Electric Stimulation; Humans; Ileum; In Vitro Techniques; Indomethacin; Jejunum; Muscle Contraction; | 1977 |
Influence of indomethacin and aspirin on the contractile effects of prostaglandin F2alpha (PGF2alpha) at different Ca++ concentrations (experiments on guinea-pig ileum).
Topics: Animals; Aspirin; Calcium; Cations, Divalent; Dose-Response Relationship, Drug; Drug Interactions; G | 1977 |
Accelerated ovum transport in rabbits induced by endotoxin II. Changes in oviductal smooth muscle activity.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Endotoxins; Fallopian Tubes; Female; Indomethaci | 1978 |
Significance of the prostaglandin system to the control of muscle tone of the ductus arteriosus.
Topics: Animals; Animals, Newborn; Arachidonic Acids; Ductus Arteriosus; Female; Fetus; Glutathione; Indomet | 1978 |
Inhibition of prostaglandin biosynthesis in rat small intestine by SL-573.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Borohydrides; Cattle; Depression, Chemical; Do | 1978 |
Spasmolytic action of histamine in airway smooth muscle of horse.
Topics: Animals; Atropine; Bronchi; Burimamide; Cimetidine; Histamine; Horses; In Vitro Techniques; Indometh | 1978 |
Interactions of calcium, prostaglandins and indomethacin on the smooth muscle of the bladder.
Topics: Animals; Calcium; Indomethacin; Muscle Contraction; Muscle, Smooth; Potassium; Prostaglandins E; Pro | 1978 |
Angiotensin analogs: effect of prostaglandin synthesis inhibitor.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Aorta, Thoracic; Arteries; Dose-Response R | 1978 |
The effects of hypoxia and indomethacin on the responsiveness of fetal and neonatal mesenteric arteries to epinephrine.
Topics: Animals; Animals, Newborn; Blood Vessels; Epinephrine; Female; In Vitro Techniques; Indomethacin; Me | 1978 |
Ductus arteriosus: developmental response to oxygen and indomethacin.
Topics: Animals; Animals, Newborn; Ductus Arteriosus; Gestational Age; Indomethacin; Muscle Contraction; Oxy | 1978 |
Developmental responses to oxygen, arachidonic acid, and indomethacin in the fetal lamb ductus arteriosus in vitro.
Topics: Animals; Arachidonic Acids; Ductus Arteriosus; Female; Gestational Age; In Vitro Techniques; Indomet | 1978 |
Prostaglandin mediated relaxation of coronary artery strips under hypoxia.
Topics: Acetylcholine; Animals; Aspirin; Cattle; Coronary Vessels; In Vitro Techniques; Indomethacin; Muscle | 1978 |
Electrical activity of human colonic smooth muscle in vitro.
Topics: Acetylcholine; Action Potentials; Colon; Humans; In Vitro Techniques; Indomethacin; Muscle Contracti | 1978 |
Problem of patent ductus arteriosus in premature infants.
Topics: Animals; Aspirin; Blood Pressure; Coronary Circulation; Ductus Arteriosus, Patent; Heart Failure; He | 1978 |
[Effect of indomethacin on the contractile responses of guinea pig tracheal tissues with various bronchoconstrictors (author's transl)].
Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; | 1978 |
Effects of prostaglandins on vesicourethral smooth muscle of rabbit. Therapeutic implications.
Topics: Acetylcholine; Animals; Barium; Female; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle C | 1978 |
Effects of prostaglandins and indomethacin on rat epididymal responses to norepinephrine and acetylcholine.
Topics: Acetylcholine; Animals; Epididymis; Indomethacin; Male; Muscle Contraction; Norepinephrine; Prostagl | 1978 |
Drug-induced motility of sow (Sus scrofa) graafian follicles isolated during pre and post-ovulatory periods of the sex cycle.
Topics: Acetylcholine; Animals; Cocaine; Female; Indomethacin; Muscle Contraction; Norepinephrine; Ovarian F | 1977 |
Studies on closure of the ductus arteriosus. XII. In utero effect of indomethacin and sodium salicylate in rats and rabbits.
Topics: Animals; Cyclooxygenase Inhibitors; Depression, Chemical; Dose-Response Relationship, Drug; Ductus A | 1975 |
Evidence for enhanced venous smooth muscle turnover of prostaglandin-like substance in portal veins from spontaneously hypertensive rats.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Arachidonic Acids; Drug Interactions; Hype | 1976 |
Inhibition of prostaglandin activity and synthesis by fenbufen (a new nonsteroidal antiinflammatory agent) and one of its metabolites.
Topics: Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Cell-Free System; Cyclooxygenase Inhibitors; | 1976 |
Maintenance of the tone of the human umbilical artery by prostaglandin and thromboxane formation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans | 1976 |
The role of prostaglandins in the spontaneous motility of the fallopian tube.
Topics: Fallopian Tubes; Female; Humans; In Vitro Techniques; Indomethacin; Menstruation; Muscle Contraction | 1977 |
Presynaptic receptor systems on the noradrenergic neurones of the rabbit pulmonary artery.
Topics: Acetylcholine; Angiotensin II; Animals; Atropine; Catecholamines; Electric Stimulation; In Vitro Tec | 1977 |
Prostacyclin (PGX) is the endogenous metabolite responsible for relaxation of coronary arteries induced by arachindonic acid.
Topics: Animals; Arachidonic Acids; Arteries; Cattle; Coronary Vessels; Culture Media; Hydroxy Acids; Indome | 1977 |
Effect of indomethacin on atropine-resistant transmission in rabbit and monkey urinary bladder: evidence for involvement of prostaglandins in transmission.
Topics: Acetylcholine; Animals; Atropine; Depression, Chemical; Drug Interactions; Electric Stimulation; Fem | 1977 |
Suppression of the release of prostaglandin-like substances by hydrocortisone in vivo.
Topics: Adrenalectomy; Aldosterone; Animals; Depression, Chemical; Dogs; Electric Stimulation; Hindlimb; Hyd | 1977 |
Angiotensin II-induced contractions of rabbit splenic capsular strips and release of prostaglandins. Use of radioimmunoassays for prostaglandins E1 and E2.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Drug Interactions; Female; Indomethacin; M | 1977 |
Effects of prostaglandins on baseline pressure and responses to noradrenaline in a perfused rat mesenteric artery preparation. PGE1 as an antagonist of PGE2.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Drug Synergism; Indomethacin; Male; Mesen | 1977 |
Anti-inflammatory properties of griseofulvin.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cell Migration Inhibition; Dose-Response Relationshi | 1977 |
Migrating action potential complex of cholera: a possible prostaglandin-induced response.
Topics: Action Potentials; Animals; Aspirin; Bacterial Toxins; Female; Gastrointestinal Motility; Ileum; Ind | 1977 |
Selective inhibitory actions of sodium-p-benzyl-4-[1-oxo-2-(4-chlorobenzyl)-3-phenyl propyl] phenyl phosphonate (N-0161) and indomethacin on the biosynthesis of prostaglandins and thromboxanes from arachidonic acid.
Topics: Animals; Arachidonic Acids; Arteries; Biological Assay; Blood Platelets; Depression, Chemical; Dogs; | 1977 |
Adenosine as a natural prostaglandin antagonist in vascular smooth muscle.
Topics: Adenosine; Animals; Calcium; Drug Interactions; Indomethacin; Male; Mesenteric Arteries; Muscle Cont | 1977 |
Actions of the tricyclic antidepressant clomipramine on responses to pressor agents. Interactions with prostaglandin E2.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Clomipramine; Dibenzazepines; Drug Synergism; Ileum; | 1977 |
Differentiation of vasoconstrictor sensitivity caused by prostaglandin E in peripheral vascular beds of the rabbit.
Topics: Animals; Aorta, Thoracic; Ear; Female; Femoral Artery; Hindlimb; Indomethacin; Male; Mesenteric Arte | 1977 |
Prostaglandins and the control of muscle tone in the ductus arteriosus.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Ductus Arteriosus; Gestational Age; Glu | 1977 |
Smooth muscle sensitization induced by colchicine: is it an in vitro property of antitubulin agents?
Topics: Animals; Colchicine; Drug Interactions; Glycoproteins; Guinea Pigs; Ileum; In Vitro Techniques; Indo | 1977 |
Some possibilities for prostaglandin mediation in the contractile response to ATP of the guinea-pig digestive tract.
Topics: Adenosine Triphosphate; Animals; Digestive System; Drug Interactions; Guinea Pigs; In Vitro Techniqu | 1977 |
Modification of airway smooth muscle responses in the guinea pig by hydrocortisone, in vitro and in vivo.
Topics: Airway Resistance; Animals; Barium; Female; Guinea Pigs; Histamine; Hydrocortisone; In Vitro Techniq | 1977 |
On the relation between release of prostaglandins and contractility of rabbit splenic capsular strips.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Cocaine; Female; In Vitro Techniques; Indomethacin; Male; | 1976 |
Endogenous prostaglandins and mechanical tension in canine trachealis muscle.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Atropine; Carbachol; Dogs; Indomethacin; Membrane | 1976 |
Intrinsic prostaglandin release. A mediator of anoxia-induced relaxation in an isolated coronary artery preparation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arteries; Aspirin; Cattle; Coronary Vessels; Hypoxia; Indo | 1976 |
Effect of rubidium on responses of rabbit vas deferens to transmural stimulation and to noradrenaline.
Topics: Animals; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Metaraminol; Muscle Contract | 1976 |
Autonomic nerves versus prostaglandins in the control of rat and rabbit testicular capsular contractions in vivo and in vitro.
Topics: Animals; Autonomic Agents; Autonomic Nervous System; Depression, Chemical; Electric Stimulation; In | 1976 |
Prostaglandin biosynthesis in the human umbilical cord.
Topics: Arachidonic Acids; Humans; Indomethacin; Muscle Contraction; Muscle, Smooth; Prostaglandins; Prostag | 1976 |
Prostaglandin endoperoxide and thromboxane generating systems and their selective inhibition.
Topics: Animals; Arachidonic Acids; Benzydamine; Blood Platelets; Horses; Hydroxy Acids; Indomethacin; Male; | 1976 |
Paradoxical endogenous synthesis of a coronary dilating substance from arachidonate.
Topics: Animals; Arachidonic Acids; Arteries; Aspirin; Cattle; Coronary Vessels; Dogs; Dose-Response Relatio | 1976 |
Studies on the effects of prostaglandins E1, E2, A1, and A2 on the dustus arteriosus of swine in vivo using cineangiography.
Topics: Animals; Animals, Newborn; Cineangiography; Drug Interactions; Ductus Arteriosus; Indomethacin; Musc | 1976 |
Indomethacin inhibits responses to all vasoconstrictors in the rat mesenteric vascular bed: restoration of responses by prostaglandin E2.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Aspirin; Blood Pressure; Calcium; Drug Interactions; | 1976 |
N-0164 inhibits generation of thromboxane-A2-like activity from prostaglandin endoperoxides by human platelet microsomes.
Topics: Animals; Aorta; Arachidonic Acids; Blood Platelets; Humans; Hydroxy Acids; Indomethacin; Male; Micro | 1976 |
Release of prostaglandins from the isolated perfused rabbit ear by bradykinin and acetylcholine.
Topics: Acetylcholine; Administration, Topical; Animals; Biological Assay; Bradykinin; Dose-Response Relatio | 1976 |
Effect of indomethacin and prostaglandin on the smooth muscle contracting activity of angiotensin and other agonists.
Topics: Acetylcholine; Angiotensin II; Animals; Bradykinin; Drug Interactions; Epinephrine; Female; Guinea P | 1976 |
Pharmacological study of phospholipase A from Vipera ammodytes venom.
Topics: Acetylcholine; Animals; Blood Pressure; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Muscl | 1976 |
Effects of oxytocin on in vitro ovarian contractility during the estrous cycle of the rat.
Topics: Animals; Estrus; Female; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Ovar | 1976 |
Effects of inhibitors of prostaglandin synthesis on rebound excitation of guinea-pig small bowel.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Female; Gastroin | 1976 |
Prostaglandins: a possible regulator of muscle tone in the ductus arteriosus.
Topics: Animals; Animals, Newborn; Ductus Arteriosus; Female; Glutathione; Heart Septal Defects; Humans; Ind | 1976 |
Relaxation of splenic strips during wash out with amine-free solution after an exposure to noradrenaline.
Topics: Animals; Biological Transport; Catechol O-Methyltransferase Inhibitors; Cats; Cocaine; Corticosteron | 1976 |
Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac ateries and inhibits platelet aggregation.
Topics: Animals; Arachidonic Acids; Celiac Artery; Drug Interactions; Indomethacin; Mesenteric Arteries; Mus | 1976 |
Relationship between the inhibitory activity on 'RCS' and prostaglandins synthesis and the anti-inflammatory activity of ketoprofen and several other non-steroidal anti-inflammatory agents.
Topics: Abscess; Animals; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Aspirin; Benzophenones; Colon; | 1976 |
Role of prostaglandins in tone and effector reactivity of the isolated rat stomach preparation.
Topics: Acetylcholine; Animals; Fatty Acids, Essential; In Vitro Techniques; Indomethacin; Male; Muscle Cont | 1975 |
Activity of prostaglandin E, F, A and B on sphincter, dilator and ciliary muscle preparations of the cat eye.
Topics: Animals; Atropine; Cats; Ciliary Body; Drug Synergism; Epinephrine; Indomethacin; Iris; Isoprotereno | 1975 |
Lamb ductus arteriosus: effect of prostaglandin synthesis inhibitors on the muscle tone and the response to prostaglandin E2.
Topics: Animals; Arachidonic Acids; Depression, Chemical; Ductus Arteriosus; Female; Indomethacin; Muscle Co | 1975 |
Multiple sites of interaction between prostaglandins and non-steroidal anti-inflammatory agents.
Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents; Cell-Free System; Colon; Depression, Chemical; Dr | 1975 |
Modulation by prostaglandins of contractions in guinea-pig ileum.
Topics: Acetylcholine; Animals; Depression, Chemical; Electric Stimulation; Female; Guinea Pigs; Histamine; | 1975 |
Angiotensin II stimulation of prostaglandin production in cultured human vascular endothelium.
Topics: Angiotensin II; Capillary Permeability; Culture Techniques; Depression, Chemical; Dose-Response Rela | 1975 |
Evidence against prostaglandin E having a physiological role in acetylcholine liberation from Auerbach's plexus of guinea-pig ileum.
Topics: Acetylcholine; Animals; Biological Assay; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniq | 1975 |
Indomethacin potentiation of the response of the rabbit portal vein to electrical stimulation: effect of stimulus frequency and train length.
Topics: Animals; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Norepine | 1975 |
Evidence that prostaglandin is responsible for the 'rebound contraction' following stimulation of non-adrenergic, non-cholinergic ('purinergic') inhibitory nerves.
Topics: Adenosine Triphosphate; Animals; Colon; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indo | 1975 |
Contractility of rat testicular seminiferous tubules in vitro: prostaglandin f 1 alpha and indomethacin-1,2.
Topics: Animals; Depression, Chemical; Indomethacin; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; | 1975 |
Effects of prostaglandin E2 and indomethacin on responses of the isthmus of rabbit oviduct to norepinephrine and transmural stimulation.
Topics: Animals; Electric Stimulation; Fallopian Tubes; Female; In Vitro Techniques; Indomethacin; Muscle Co | 1975 |
Prostaglandin endoperoxides IX. Characterization of rabbit aorta contracting substance (RCS) from guinea pig lung and human platelets.
Topics: Animals; Aorta, Thoracic; Arachidonic Acids; Aspirin; Blood Platelets; Humans; Indomethacin; Lung; M | 1975 |
Contractile responses of the guinea-pig trachea in vitro: modification by prostaglandin synthesis-inhibiting drugs.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Animals; Anti-Inflammatory Agents; Aspirin; Barium; | 1975 |
Effect of prostaglandin E2 on the pressor response to periarterial stimulation and norepinephrine of the isolated perfused rabbit kidney.
Topics: Animals; Aorta; Aspirin; Depression, Chemical; Drug Interactions; Electric Stimulation; Female; Indo | 1975 |
Reduction of antigen-induced contraction of sensitized human bronchus in vitro by indomethacin.
Topics: Acetylcholine; Antigens; Arachidonic Acids; Bronchi; Humans; In Vitro Techniques; Indomethacin; Musc | 1975 |
In vitro production of prostaglandins by isolated aorta strips of normotensive and hypertensive rats.
Topics: Animals; Aorta, Thoracic; Female; Hypertension; In Vitro Techniques; Indomethacin; Male; Muscle Cont | 1975 |
Reduction of the tone of the isolated human umbilical artery by indomethacin, eicosa-5,8,11,14-tetraynoic acid and polyphloretin phosphate.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Depression, Chemical; Dose-Response Relationship, Drug; Drug Intera | 1975 |
Pharmacological influences upon the contractile activity of isolated guinea pig epididymis.
Topics: Animals; Epididymis; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Phentolamine; Prostaglandi | 1975 |
Modifications of canine vascular smooth muscle responses to dihydroergotamine by endogenous prostaglandin synthesis.
Topics: Animals; Arachidonic Acids; Blood Vessels; Dihydroergotamine; Dogs; Drug Interactions; Ergotamines; | 1975 |
Suprofen, a potent antagonist of acetic acid-induced writhing in rats.
Topics: Acetates; Analgesics; Animals; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Drug Ev | 1975 |
Endogenous prostaglandin in guinea pig taenia coli.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Action Potentials; Animals; Aspirin; Atropine; Carbachol; Colon; Do | 1976 |
The effect of cocaine, desipramine, 6-hydroxydopamine and indomethacin on the sensitivity of the estrogen-dominated ampulla of rabbit oviduct to (-)-norepinephrine.
Topics: Animals; Cocaine; Desipramine; Drug Synergism; Female; Hydroxydopamines; Indomethacin; Muscle Contra | 1976 |
Some biological effects of prostaglandin endoperoxide analogs.
Topics: Animals; Aorta; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Peroxides; Pl | 1976 |
Prostaglandin production by rabbit isolated jejunum and its relationship to the inherent tone of the preparation.
Topics: Animals; In Vitro Techniques; Indomethacin; Jejunum; Muscle Contraction; Muscle Tonus; Muscle, Smoot | 1976 |
Effects of indomethacin and PGE1 on the vasoconstrictor responses of the rabbit ear artery to nerve stimulation.
Topics: Animals; Arteries; Ear; Electric Stimulation; Indomethacin; Muscle Contraction; Muscle, Smooth; Pros | 1976 |
Prostacyclin rather than nitric oxide lowers human umbilical artery tone in vitro.
Topics: Arginine; Bradykinin; Cyclic GMP; Epoprostenol; Female; Histamine; Humans; Iloprost; In Vitro Techni | 1992 |
Influence of endothelium in the in vitro vasorelaxant effect of magnesium on aortic basal tension in DOCA-salt hypertensive rat.
Topics: Animals; Aorta, Thoracic; Arginine; Desoxycorticosterone; Endothelium, Vascular; Hypertension; In Vi | 1992 |
Omega-conotoxin-sensitive calcium channels modulate autonomic neurotransmission in guinea pig airways.
Topics: Acetylcholine; Animals; Atropine; Autonomic Nervous System; Bronchi; Calcium Channels; Capsaicin; Ch | 1992 |
Activated neutrophils alter contractile properties of the pulmonary artery.
Topics: Animals; Catalase; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Methacrylates; Muscle Contrac | 1992 |
The modulatory effects of prostaglandins on both excitatory and inhibitory non-adrenergic non-cholinergic neurotransmission in guinea-pig airways.
Topics: Acetylcholine; Animals; Bronchi; Dinoprostone; Electric Stimulation; Guinea Pigs; In Vitro Technique | 1992 |
Local motor responses to bradykinin and bacterial chemotactic peptide formyl-methionyl-leucyl-phenylalanine (FMLP) in the guinea-pig isolated renal pelvis and ureter.
Topics: Animals; Bradykinin; Calcitonin; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relations | 1992 |
Tachykinins and calcitonin gene-related peptide as co-transmitters in local motor responses produced by sensory nerve activation in the guinea-pig isolated renal pelvis.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Tec | 1992 |
Effects of the medium chain octanoic fatty acid on the contractile activity of vascular smooth muscle tissues.
Topics: Animals; Caprylates; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide | 1992 |
Mechanisms of action of cicletanine in human and guinea pig resistance arteries.
Topics: Animals; Antihypertensive Agents; Arteries; Charybdotoxin; Diuretics; Drug Interactions; Eicosanoids | 1992 |
Endothelins constrict guinea pig tracheas by multiple mechanisms.
Topics: Animals; Arachidonic Acid; Calcium Channel Blockers; Endothelins; Guinea Pigs; Histamine Release; In | 1992 |
Slow channel calcium blockers attenuate reoxygenation-mediated vascular contraction, but augment anoxia-mediated vascular contraction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aorta; D | 1992 |
Potassium channel activation in vascular smooth muscle.
Topics: Animals; Antihypertensive Agents; Basilar Artery; Carotid Arteries; Coronary Vessels; Diuretics; Dog | 1992 |
Relationship between histamine, lipoxygenase and cyclooxygenase products in antigen-induced contraction in guinea-pig tracheal tube preparations.
Topics: Animals; Antigens; Eicosanoids; Epithelium; Female; Guinea Pigs; Histamine; Indoles; Indomethacin; L | 1992 |
Mechanical effects of some prostanoids on isolated human oesophageal submucosal veins.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Drug Interactions; Esophagus; Fe | 1992 |
Variable effects of human and canine polymorphonuclear leucocytes on vascular smooth muscle tone.
Topics: Animals; Arginine; Arteries; Chromones; Culture Techniques; Dogs; Endothelium; Humans; Indomethacin; | 1992 |
Studies on the electrical stimulation-induced contractile responses of hamster and mouse gallbladders.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Atropine; Cricetinae; Electric Stimulation; Ethanol; Gallb | 1992 |
Increased sensitivity of guinea pig gallbladder in vitro to bradykinin.
Topics: Animals; Bradykinin; Carbachol; Cycloheximide; Gallbladder; Guinea Pigs; In Vitro Techniques; Indome | 1992 |
Endothelium-dependent increase in vascular sensitivity to phenylephrine in long-term streptozotocin diabetic rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Endothelium, Vascular; Ind | 1992 |
Effects of indomethacin on myogenic contractile activation and responses to changes in O2 and CO2 in isolated feline cerebral arteries.
Topics: Animals; Carbon Dioxide; Cats; Cerebral Arteries; Female; Hypercapnia; Hypoxia; In Vitro Techniques; | 1992 |
Effects on the rabbit coronary artery of LP-805, a new type of releaser of endothelium-derived relaxing factor and a K+ channel opener.
Topics: Acetylcholine; Action Potentials; Animals; Coronary Vessels; Glyburide; In Vitro Techniques; Indomet | 1992 |
Endothelial modulation of the ouabain-induced contraction in human placental vessels.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adult; Arginine; Arteries; Biological Assay; Blood Vessels; Endothe | 1992 |
A possible role for urinary bladder epithelium in bradykinin-induced contraction in diabetic rats.
Topics: Animals; Bradykinin; Diabetes Mellitus, Experimental; Dinoprost; Dinoprostone; Epithelium; In Vitro | 1992 |
Porcine pancreatic phospholipase A2-induced contractions of guinea pig lung pleural strips.
Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; E | 1992 |
Histamine receptors on human isolated pulmonary arterial muscle preparations: effects of endothelial cell removal and nitric oxide inhibitors.
Topics: Arginine; Burimamide; Chlorpheniramine; Cimetidine; Dimaprit; Endothelium, Vascular; Histamine; Huma | 1992 |
Endothelium-dependent contractile responses to 5-hydroxytryptamine in the rabbit basilar artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arginine; Basilar Artery; Endothelium, Vascular; Fe | 1992 |
Endothelin-1 inhibits and enhances contraction of porcine coronary arterial strips with an intact endothelium.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Bradykinin; C | 1992 |
Protective effect of propranolol on ethanol-induced gastric lesions in rats: probable mechanism of action.
Topics: Animals; Drug Interactions; Ethanol; Gastric Fundus; Gastrointestinal Hemorrhage; Indomethacin; Lido | 1992 |
A pharmacological in vitro study of the mouse urinary bladder at the time of acute change in bladder reservoir function after irradiation.
Topics: Acetylcholine; Animals; Carbachol; Electric Stimulation; Guanidines; In Vitro Techniques; Indomethac | 1992 |
Isolated pulmonary resistance vessels from fetal lambs. Contractile behavior and responses to indomethacin and endothelin-1.
Topics: Animals; Delivery, Obstetric; Endothelins; Female; Fetus; In Vitro Techniques; Indomethacin; Lung; M | 1992 |
Estradiol effect on indomethacin and prostaglandin E2-modulation of adrenergic transmission in rabbit oviduct.
Topics: Adrenergic Fibers; Animals; Dinoprostone; Electric Stimulation; Estradiol; Fallopian Tubes; Female; | 1991 |
Bradykinin and angiotensin II inhibit neurotransmission in rabbit ear artery by releasing prostanoids.
Topics: Angiotensin II; Animals; Arteries; Bradykinin; Ear; Electric Stimulation; Enkephalin, Methionine; In | 1991 |
In vitro characteristics of spontaneous airway tone in the guinea-pig.
Topics: Animals; Bronchi; Chromones; Cyclooxygenase Inhibitors; Guinea Pigs; In Vitro Techniques; Indomethac | 1991 |
The mechanism of LTE4-induced histamine hyperresponsiveness in guinea-pig tracheal and human bronchial smooth muscle, in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Animals; Atropine; Bipheny | 1991 |
Regional effects of indomethacin, acetylsalicylic acid and SC-19220 on the contractility of rabbit renal pelvis (pacemaker regions and pelviureteric junction).
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-ch | 1991 |
Selective production of endothelium-derived nitric oxide in canine femoral veins.
Topics: Acetylcholine; Adenosine Diphosphate; Adrenergic beta-Antagonists; Animals; Arginine; Azepines; Calc | 1991 |
Effects of palytoxin on guinea pig tracheal strips.
Topics: Acrylamides; Airway Resistance; Animals; Atropine; Calcium; Cnidarian Venoms; Guinea Pigs; In Vitro | 1991 |
Influence of short-chain fatty acids on vascular tone.
Topics: Animals; Aspirin; Blood Pressure; Cats; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro- | 1991 |
Suppression by neuropeptide Y of capsaicin-sensitive sensory nerve-mediated contraction in guinea-pig airways.
Topics: Animals; Atropine; Bronchi; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indom | 1990 |
Contractile activity of three endothelins (ET-1, ET-2 and ET-3) on the human isolated bronchus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Substance P contracts bovine tracheal smooth muscle via activation of myosin light chain kinase.
Topics: Animals; Atropine; Calcium; Cattle; Enzyme Activation; Glycopeptides; In Vitro Techniques; Indometha | 1990 |
Pharmacological modulation of the contractile response to toluene diisocyanate in the rat isolated urinary bladder.
Topics: Animals; Atropine; Capsaicin; In Vitro Techniques; Indomethacin; Male; Methylprednisolone; Muscle Co | 1990 |
Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in alpha-adrenoceptor responsiveness with age and disease in isolated tissues.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Calcium dependence of the contraction produced by endothelin (ET-1) in isolated guinea-pig trachea.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Influence of indomethacin and L-cysteine on histamine and peptidoleukotriene release from superfused tracheas taken from guinea pigs passively sensitized with IgG1 and IgE antibodies.
Topics: Animals; Cysteine; Female; Guinea Pigs; Histamine Release; Immunization; Immunoglobulin E; Immunoglo | 1991 |
Low pH-induced release of calcitonin gene-related peptide from capsaicin-sensitive sensory nerves: mechanism of action and biological response.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5 | 1991 |
Endothelial cells are required for inhibition of contractile responses induced by reduction in extracellular magnesium and sodium ions in rat aortic smooth muscle [corrected].
Topics: Animals; Aorta, Thoracic; Atropine; Calcium; Endothelium, Vascular; Female; Indomethacin; Magnesium; | 1990 |
Prostaglandin E2 and fetal oxygen tension synergistically inhibit response of isolated fetal rabbit ductus arteriosus to norepinephrine.
Topics: Animals; Dinoprostone; Drug Synergism; Ductus Arteriosus; Female; Fetus; In Vitro Techniques; Indome | 1991 |
Endothelium-dependent response of the rabbit aorta to femtomolar concentrations of angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Kinetics; | 1991 |
Inhibitory effects of cyclic AMP-elevating agents on norepinephrine-induced phosphatidylinositide hydrolysis and contraction in rat aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Buclades | 1991 |
Pharmacological characterization of the vascular muscarinic receptors mediating relaxation and contraction in rabbit aorta.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Antihy | 1991 |
Desensitization of alpha-adrenergic receptor-mediated smooth muscle contraction: role of the endothelium.
Topics: Adrenal Gland Neoplasms; Animals; Aorta, Thoracic; Endothelium, Vascular; Female; Hemoglobins; In Vi | 1991 |
Characterization of bradykinin receptors in peripheral organs.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Bradykinin; Cricetinae; Guine | 1991 |
Bronchial smooth muscle responses evoked by toluene diisocyanate are inhibited by ruthenium red and by indomethacin.
Topics: Animals; Bronchi; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Ruthenium Red | 1991 |
CAS 936, a novel syndnonimine with direct vasodilating and nitric oxide-donating properties: effects on isolated blood vessels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcimycin; Guinea Pigs | 1991 |
Effects of vasoactive intestinal peptide, helodermin and galanin on responses of guinea-pig lung parenchyma to histamine, acetylcholine and leukotriene D4.
Topics: Acetylcholine; Albuterol; Animals; Galanin; Guinea Pigs; Histamine; Histamine Antagonists; In Vitro | 1991 |
Endothelium-dependent nonadrenergic, noncholinergic neural relaxation in guinea pig pulmonary artery.
Topics: Acetamides; Adenosine Triphosphate; Animals; Arginine; Atropine; Autonomic Nervous System; Capsaicin | 1992 |
Effect of endothelin-1 on guinea pig gallbladder smooth muscle in vitro.
Topics: Animals; Arachidonic Acid; Atropine; Calcium; Cations, Divalent; Diltiazem; Endothelins; Gallbladder | 1992 |
Pharmacologic evaluation of A23187-induced contractions of three distinct preparations of guinea pig lung parenchymal strips.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcimycin; Drug Intera | 1992 |
The interaction of acetylcholine and histamine on human bronchial smooth muscle contraction.
Topics: Acetylcholine; Asthma; Atropine; Bronchi; Dose-Response Relationship, Drug; Drug Interactions; Epith | 1991 |
Comparison of responses to angiotensin II of dog mesenteric arteries and veins.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Arachidonic Acid; Calcimycin; Dogs; Endotheli | 1991 |
Effects and specific binding sites of endothelin in human lung preparations.
Topics: Binding Sites; Calcium Channel Blockers; Endothelins; Humans; In Vitro Techniques; Indomethacin; Iod | 1991 |
Attenuated responses to endothelin-1, KCl and CaCl2, but not noradrenaline, of aortae from rats with streptozotocin-induced diabetes mellitus.
Topics: Animals; Aorta, Thoracic; Body Weight; Calcium Chloride; Diabetes Mellitus, Experimental; Electric S | 1991 |
NIP-121 and cromakalim, potassium channel openers, preferentially suppress prostanoid-induced contraction of the guinea-pig isolated trachea.
Topics: Animals; Arachidonic Acid; Benzopyrans; Cromakalim; Dinoprost; Glyburide; Guinea Pigs; Indomethacin; | 1991 |
Non-adrenergic, non-cholinergic regulation of guinea-pig airway smooth muscle-indomethacin-induced changes and segmental differences.
Topics: Animals; Autonomic Nervous System; Bronchi; Electric Stimulation; Female; Guinea Pigs; Humans; In Vi | 1991 |
15-lipoxygenase metabolites of arachidonic acid evoke contractions and relaxations in isolated canine arteries: role of thromboxane receptors, endothelial cells and cyclooxygenase.
Topics: Animals; Arachidonate 15-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Arteries; Coronary Vesse | 1991 |
Effects of indomethacin, endothelium-denudation, methylene blue and L-NG-monomethyl arginine on the vasoactive effects of endothelin-3.
Topics: Animals; Arginine; Cholic Acids; Endothelins; Endothelium, Vascular; In Vitro Techniques; Indomethac | 1991 |
Epithelial modulation of airway smooth muscle response to endothelin-1.
Topics: Animals; Bronchoconstriction; Endothelins; Epithelium; Guinea Pigs; Indomethacin; Male; Muscle Contr | 1991 |
Effects of dantrolene on the responses to methylxanthines in the isolated guinea-pig trachea.
Topics: Acetylcholine; Albuterol; Animals; Caffeine; Calcium; Dantrolene; Female; Guinea Pigs; Indomethacin; | 1991 |
IgE-dependent activation of alveolar macrophages augments neurally mediated contraction of small airways.
Topics: Acetylcholine; Animals; Bronchi; Dinitrophenols; Dogs; Eicosanoids; Electric Stimulation; Female; Im | 1991 |
Persistent effects of interleukin-1 on smooth muscle preparations from adrenalectomized rats: implications for increased phospholipase-A2 activity via stimulation of 5-lipoxygenase.
Topics: Adrenalectomy; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Aspirin; C | 1991 |
Inhibitory effect of dietary administration of eicosapentaenoic acid on the contractions of guinea-pig tracheal smooth muscle induced by leukotriene C4 and D4.
Topics: Animals; Benzoquinones; Body Weight; Chromatography, High Pressure Liquid; Diet; Eicosapentaenoic Ac | 1991 |
Modulation of equine tracheal smooth muscle contractility by epithelial-derived and cyclooxygenase metabolites.
Topics: Acetylcholine; Animals; Arachidonic Acids; Biological Factors; Cyclooxygenase Inhibitors; Dinoprosto | 1991 |
Involvement of capsaicin-sensitive nerves in the bronchomotor effects of arachidonic acid and melittin: a possible role for lipoxin A4.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzeneacetamides; Bronchi; Capsaicin; Epithelium; Gui | 1991 |
Action of noradrenaline on isolated proximal and distal coronary arteries of rat: selective release of endothelium-derived relaxing factor in proximal arteries.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Arteries; Azepines; Coronary Vessels; Dinoprost; | 1990 |
Endogenous AA metabolites and their possible role in tracheal smooth muscle tone in guinea pigs.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Chromones; Dibenz(b,f)(1,4)oxazepine-10 | 1990 |
Antianaphylactic and antihistaminic activity of the non-steroidal anti-inflammatory compound nimesulide in guinea-pig.
Topics: Airway Resistance; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; B | 1990 |
Responses of rat isolated intestinal segments to stimulation of perivascular mesenteric nerve fibres.
Topics: Animals; Atropine; Capsaicin; Electric Stimulation; Female; Ganglionic Blockers; Hexamethonium; Hexa | 1990 |
Purification and characterization of Contractin A from the pedicellarial venom of sea urchin, Toxopneustes pileolus.
Topics: Amino Acid Sequence; Animals; Guinea Pigs; Indomethacin; Male; Marine Toxins; Molecular Sequence Dat | 1991 |
Endothelium-dependent effects of pentoxifylline in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Colforsin; Endothelium, Vascular; In Vitro Techniques; Indo | 1991 |
Study of the contraction induced by norepinephrine and clonidine in the isolated guinea-pig ileum.
Topics: Animals; Atropine; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle Co | 1991 |
Mechanisms of action of endothelin 1 in maturing rabbit airway smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Aging; Animals; Dinoprostone; Eicosano | 1991 |
Effect of different bronchodilators on airway smooth muscle responsiveness to contractile agents.
Topics: Animals; Bronchodilator Agents; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; | 1991 |
Selective implication of thromboxane A2 and PAF-acether in two guinea pig anaphylactic models.
Topics: Anaphylaxis; Animals; Antigens; Glyceryl Ethers; Guinea Pigs; Immunoglobulin E; Immunoglobulin G; In | 1990 |
Regional differences in the prostanoid receptors mediating prostaglandin F2 alpha-induced contractions of cat isolated arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compoun | 1990 |
The effect of indomethacin and metamizole on ureteral motility and urine flow in sheep.
Topics: Animals; Colic; Dipyrone; Dose-Response Relationship, Drug; Female; Indomethacin; Kidney Diseases; M | 1990 |
Effects of indomethacin on neural and myogenic components in equine airway smooth muscle.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Animals; Atropine; Dinoprostone; Horses; In Vitro Te | 1990 |
Pertussis toxin inhibits endothelium-dependent relaxations evoked by fluoride.
Topics: Acetylcholine; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Coronary Vessels | 1990 |
Sensitization of group III muscle afferents to static contraction by arachidonic acid.
Topics: Action Potentials; Afferent Pathways; Animals; Arachidonic Acid; Arachidonic Acids; Cats; Electric S | 1990 |
Endothelium-dependent effects of cigarette smoke components on tone of porcine intrapulmonary arteries in vitro.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Endothelium, Vascular; Hexamethonium Compounds; In Vitr | 1990 |
Ebselen inhibits contractile responses of guinea-pig parenchymal lung strips.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azo | 1990 |
Differential modulation by basilar and mesenteric endothelium of angiotensin-induced contraction in canine arteries.
Topics: Acetylcholine; Angiotensin II; Angiotensin III; Animals; Basilar Artery; Dogs; Endothelium, Vascular | 1990 |
Cyclooxygenase blockade attenuates responses of group IV muscle afferents to static contraction.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cats; Cyclooxygenase Inhibitors; Indomethacin; Muscle | 1990 |
Defibrotide, by enhancing prostacyclin generation, prevents endothelin-1 induced contraction in human saphenous veins.
Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Cyclooxygenase Inhibitors; Dinoprostone; Endothelin | 1990 |
Modulation of bradykinin responses in airway smooth muscle by epithelial enzymes.
Topics: Animals; Bradykinin; Cyclooxygenase Inhibitors; Epithelium; Glycopeptides; Guinea Pigs; Indomethacin | 1990 |
Effects of prostaglandin synthetase inhibitors on the upper urinary tract. Experimental studies on isolated preparations and urodynamic measurements in men.
Topics: Adult; Cyclooxygenase Inhibitors; Dipyrone; Female; Humans; Indomethacin; Kidney Pelvis; Male; Middl | 1990 |
Effects of m-nisoldipine on anoxia-potentiated histamine and acetylcholine-induced contractions of the porcine isolated coronary artery.
Topics: Acetylcholine; Animals; Coronary Vessels; Histamine Antagonists; Hypoxia; In Vitro Techniques; Indom | 1990 |
Role of thromboxane A2/prostaglandin H2 receptor in the vasoconstrictor response of rat aorta to endothelin.
Topics: Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Endothelins; Fatty Acids, | 1990 |
Hypoxic and posthypoxic responses in isolated coronary arteries and veins: role of endothelium.
Topics: Animals; Calcium; Coronary Circulation; Coronary Vessels; Dogs; Endothelium, Vascular; Gallopamil; I | 1990 |
Beta-adrenoceptor desensitization induced by antigen challenge in guinea-pig trachea.
Topics: Animals; Antigens; Arachidonic Acid; Arachidonic Acids; Eicosanoids; Epinephrine; Guinea Pigs; Hydro | 1990 |
Pharmacologic characterization of the contractile activity of peptide leukotrienes in guinea-pig pulmonary artery.
Topics: Acetophenones; Animals; Borates; Drug Synergism; Endothelium, Vascular; Guinea Pigs; In Vitro Techni | 1990 |
Relaxation of canine airway smooth muscle by the heparin preservative benzyl alcohol.
Topics: Acetylcholine; Animals; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Bronchi; Cyclic AMP; Dogs | 1990 |
Endothelin modulation of neuroeffector transmission in rat and guinea pig vas deferens.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Triphosphate; Animals; Auton | 1990 |
Purinoceptor desensitization impairs but does not abolish the non-cholinergic motor transmission in rat isolated urinary bladder.
Topics: Adenosine Triphosphate; Animals; Atropine; Autonomic Nervous System; Electric Stimulation; Electrode | 1990 |
Further studies on the response of the guinea-pig isolated bronchus to endothelins and sarafotoxin S6b.
Topics: Animals; Aorta, Thoracic; Bronchi; Captopril; Endothelins; Epithelium; Guinea Pigs; In Vitro Techniq | 1990 |
Preventive effects of indomethacin on diaphragmatic contractile alterations in endotoxemic rats.
Topics: Animals; Diaphragm; Endotoxins; Escherichia coli; Indomethacin; Male; Muscle Contraction; Rats; Rats | 1990 |
Simultaneous release of endothelium-derived relaxing and contracting factors induced by noradrenaline in normotensive rats.
Topics: Animals; Aorta, Thoracic; Endothelins; Endothelium, Vascular; Female; In Vitro Techniques; Indometha | 1990 |
Effect of flush-perfusion with Euro-Collins solution on pulmonary arterial function.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Bradykinin; Calcimycin; Dogs; Endothelium, Vascular; | 1990 |
Vagal innervation of guinea pig bronchial smooth muscle.
Topics: Animals; Bronchi; Electric Stimulation; Electrophysiology; Ganglia, Parasympathetic; Guinea Pigs; In | 1990 |
The level of spontaneous myogenic tone in isolated human posterior ciliary arteries decreases with age.
Topics: Acetylcholine; Adult; Aged; Aging; Arteries; Ciliary Body; Dose-Response Relationship, Drug; Endothe | 1990 |
Carbamylcholine- and 5-hydroxytryptamine-induced contraction in rat isolated airways: inhibition by calcitonin gene-related peptide.
Topics: Animals; Bronchi; Calcitonin Gene-Related Peptide; Carbachol; Humans; In Vitro Techniques; Indometha | 1990 |
Role of neuropeptide Y in opossum internal anal sphincter.
Topics: Anal Canal; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Guanethidine; | 1990 |
Indomethacin improves the impaired endothelium-dependent relaxations in small mesenteric arteries of the spontaneously hypertensive rat.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Hypertension; Indomethacin; Isometric Contraction; Ma | 1990 |
Effects of PGF2 alpha and of indomethacin on rabbit small and large intestinal motility in vivo.
Topics: Animals; Colon; Computer Simulation; Dinoprost; Evoked Potentials; Gastrointestinal Motility; Ileum; | 1990 |
The effect of neomycin on contractile activity of the canine cervical lymphatic vessel induced by various agents.
Topics: Animals; Dogs; Female; In Vitro Techniques; Indomethacin; Isometric Contraction; Lymphatic System; M | 1990 |
The effect of inhibitors of prostaglandin formation on contraction of the rat, rabbit and human vas deferens.
Topics: Animals; Dinoprost; Dinoprostone; Ethanol; Humans; Indomethacin; Male; Muscle Contraction; Rabbits; | 1990 |
Effect of nifedipine on the contractile responses of the isolated rat bladder.
Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro T | 1990 |
Inhibitory effects of OKY-046 on spasmogen-induced bronchoconstrictions in sensitized and non-sensitized guinea pigs.
Topics: Acrylates; Animals; Blood Pressure; Bordetella pertussis; Bronchi; Guinea Pigs; Histamine; In Vitro | 1990 |
Responses of equine trachealis and lung parenchyma to methacholine, histamine, serotonin, prostanoids, and leukotrienes in vitro.
Topics: Animals; Asthma; Atropine; Disease Models, Animal; Histamine; Horses; In Vitro Techniques; Indometha | 1990 |
Modulation of the reactivity of the guinea-pig isolated trachealis by respiratory epithelium: effects of cooling.
Topics: Animals; Cold Temperature; Epithelium; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Methach | 1990 |
[Tyr0]-calcitonin gene-related peptide 28-37 (rat) as a putative antagonist of calcitonin gene-related peptide responses on opossum internal anal sphincter smooth muscle.
Topics: Anal Canal; Animals; Blood Pressure; Calcitonin; Calcitonin Gene-Related Peptide; Heart Rate; In Vit | 1990 |
Hydrogen peroxide-induced potentiation of contractile responses in isolated rat airways.
Topics: Acetylcholine; Animals; Bronchi; Catalase; Electric Stimulation; Hydrogen Peroxide; In Vitro Techniq | 1990 |
No effect of prostaglandin synthesis inhibition on muscle reflexes in fetal lambs.
Topics: Acetaminophen; Animals; Cerebral Cortex; Differential Threshold; Electric Stimulation; Electrocardio | 1990 |
Depression by fenoprofen of the rebound contractions' elicited by vagal stimulation and arterial infusion of ATP in the rabbit stomach in vivo.
Topics: Adenosine Triphosphate; Animals; Fenoprofen; Indomethacin; Muscle Contraction; Phenylpropionates; Ra | 1990 |
Cholecystokinin causes contraction of the pupillary sphincter in monkeys but not in cats, rabbits, rats and guinea-pigs: antagonism by lorglumide.
Topics: Animals; Cats; Cholecystokinin; Eye; Female; Guinea Pigs; Indomethacin; Macaca; Macaca fascicularis; | 1990 |
The ligamentum infundibulo-cornuale in the pig: morphological and physiological studies of the smooth muscle component.
Topics: Animals; Dinoprost; Dinoprostone; Estrus; Female; Genitalia, Female; Indomethacin; Ligaments; Moveme | 1990 |
Pre-junctional inhibitory action of prostaglandin E2 on excitatory neuro-effector transmission in the human bronchus.
Topics: Bronchi; Chromones; Dinoprostone; Electric Stimulation; Humans; In Vitro Techniques; Indomethacin; I | 1990 |
Stretch-induced prostaglandins and protein turnover in cultured skeletal muscle.
Topics: Animals; Cathepsins; Cells, Cultured; Chick Embryo; Dinoprost; Dinoprostone; Indomethacin; Kinetics; | 1990 |
The inhibition of [3H]leukotriene D4 binding to guinea-pig lung membranes. The correlation of binding affinity with activity on the guinea-pig ileum.
Topics: Animals; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Indomethacin; Kinetics; L | 1990 |
Oxytocin enhances the basal release of uterine prostaglandin F2 alpha, but not that of PGE1, or of PGE2, and changes the metabolism of exogenous arachidonate, favouring the formation of prostaglandin F2 alpha and 5-HETE. Relationships with its uterotonic
Topics: Alprostadil; Animals; Arachidonic Acids; Calcium; Dinoprost; Dinoprostone; Estradiol; Female; Hydrox | 1990 |
Possible involvement of substance P in the contraction produced by periarterial nerve stimulation in the rat ileum.
Topics: Acetylcholine; Animals; Atropine; Capsaicin; Electric Stimulation; Guanethidine; Ileum; In Vitro Tec | 1985 |
Intracellular electrical activity of muscularis mucosae of the dog stomach.
Topics: Action Potentials; Animals; Calcium; Dogs; Electric Stimulation; Female; Gallopamil; Gastric Mucosa; | 1985 |
Lipoxygenase and calcium entry in vascular smooth muscle.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium Channel Blockers; Cate | 1985 |
IgG vs IgE: mediators of antigen-induced guinea pig lung parenchymal contraction.
Topics: Animals; Antigens; Atropine; Chromones; Guinea Pigs; Histamine Release; Immunoglobulin E; Immunoglob | 1985 |
5-Carboxamidotryptamine: a potent agonist mediating relaxation and elevation of cyclic AMP in the isolated neonatal porcine vena cava.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Atropine; Cimetidine; Cocaine; Cyclic AMP; D | 1986 |
The effect of indomethacin on anaphylactic contraction and histamine release in guinea-pig lung parenchymal strips.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anaphylaxis; Animals; Chromones; Femal | 1986 |
Relaxation of isolated human pulmonary muscle preparations with prostacyclin (PGI2) and its analogs.
Topics: Bronchi; Epoprostenol; Histamine; Humans; Iloprost; Indomethacin; Lung; Muscle Contraction; Muscle R | 1987 |
Characterization of substance P contractile activity on isolated guinea pig lung tissues.
Topics: Animals; Dose-Response Relationship, Drug; Glycopeptides; Guinea Pigs; In Vitro Techniques; Indometh | 1987 |
Effect of OKY-046, a new thromboxane A2 synthetase inhibitor, on experimental asthma in guinea pigs.
Topics: Acrylates; Animals; Asthma; Female; Guinea Pigs; Histamine; Histamine Release; Indomethacin; Lung; M | 1987 |
Spasmogen action in guinea-pig isolated trachealis: involvement of membrane K+-channels and the consequences of K+-channel blockade.
Topics: Animals; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Ion Channels; Male; Membrane Potent | 1988 |
Effects of substance P on isolated preparations from rabbit and rat renal arteries.
Topics: Animals; Dinoprost; Electric Stimulation; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular | 1988 |
Influence of epithelium on guinea pig airway responses to tachykinins: role of endopeptidase and cyclooxygenase.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Endopeptidases; Epithelium; Glycopeptides; Gui | 1989 |
Smooth-muscle effects of substance P.
Topics: Animals; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, In | 1988 |
Inhibition of the oxygen-induced contraction of the isolated human umbilical artery by indomethacin, flurbiprofen, aspirin and drugs modifying Ca2+ disposition.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1988 |
C3a-induced contraction of guinea pig ileum consists of two components: fast histamine-mediated and slow prostanoid-mediated.
Topics: Animals; Complement C3; Complement C3a; Guinea Pigs; Histamine; Histamine Release; Ileum; In Vitro T | 1989 |
Enhanced airway responses to substance P after repeated challenge in guinea pigs.
Topics: Animals; Atropine; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin | 1989 |
Pharmacology of endothelin-1 in isolated vessels: effect of nicardipine, methylene blue, hemoglobin, and gossypol.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
The hamster isolated trachea: a new preparation for studying NK-2 receptors.
Topics: Animals; Atropine; Cricetinae; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, | 1989 |
Multiple mechanisms in the motor responses of the guinea-pig isolated urinary bladder to bradykinin.
Topics: Animals; Apamin; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Dibenz(b,f)(1,4)oxazepine-1 | 1989 |
Pharmacological action of the phospholipase A2 from the venom of Trimeresurus flavoviridis on the smooth muscle of the rat stomach.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Crotalid Venoms; Dinoprost; Dinoprostone; Indomethacin | 1989 |
Endotoxin-induced hyperreactivity of the guinea-pig isolated trachea coincides with decreased prostaglandin E2 production by the epithelial layer.
Topics: Airway Resistance; Animals; Arachidonic Acid; Arachidonic Acids; Arecoline; Dinoprostone; Drug Inter | 1989 |
Potent contractile effect of endothelin in isolated guinea-pig airways.
Topics: Animals; Bronchi; Edetic Acid; Endothelins; Guinea Pigs; In Vitro Techniques; Indomethacin; Isoprote | 1989 |
Contraction of the rat isolated aorta caused by Clostridium perfringens alpha toxin (phospholipase C): evidence for the involvement of arachidonic acid metabolism.
Topics: Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspirin; Bacterial Toxins; Calcium-Bi | 1989 |
Spontaneous rhythmic contractions of human saphenous veins isolated from old subjects are sensitive to cyclooxygenase inhibitors.
Topics: Adult; Aged; Aging; Aspirin; Coronary Artery Bypass; Cyclooxygenase Inhibitors; Female; Histamine; H | 1989 |
N-[(arylmethoxy)phenyl] and N-[(arylmethoxy)naphthyl] sulfonamides: potent orally active leukotriene D4 antagonists of novel structure.
Topics: Acetophenones; Animals; Bronchi; Chemical Phenomena; Chemistry; Constriction, Pathologic; Cyclooxyge | 1989 |
Metabolism of 20-hydroxyeicosatetraenoic acid by cyclooxygenase. Formation and identification of novel endothelium-dependent vasoconstrictor metabolites.
Topics: Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, Thin Layer; Cyclooxygenase | 1989 |
[Mechanisms of bronchoconstriction induced by anaphylaxis in sensitized guinea pigs].
Topics: Anaphylaxis; Animals; Benzoquinones; Bronchi; Guinea Pigs; Histamine Antagonists; Indomethacin; Leuk | 1989 |
Arachidonic acid lipoxygenation may be involved in interleukin-1 induction of prostaglandin biosynthesis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium Chloride; In Vitro Techniques; Indomethacin; I | 1989 |
Leukotriene D4 and platelet-activating factor-acether antagonists on allergic and arachidonic acid-induced reactions in guinea pig airways.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Guinea Pigs; Hypersensitivity; In Vitro Techniques; In | 1989 |
Endothelium-dependent relaxation of human basilar arteries.
Topics: Acetylcholine; Adult; Aged; Basilar Artery; Benzoquinones; Calcimycin; Child; Child, Preschool; Dose | 1989 |
Are arachidonic acid metabolites involved in the hypoxic reactions of cerebrovascular smooth muscle cells?
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carotid Arteries; Dogs; Hypoxia; In Vitro Techniques; | 1989 |
Contraction followed by relaxation in response to hypoxia in the sheep isolated middle cerebral artery.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Cerebral Arteries; Endotheliu | 1989 |
Atrial natriuretic factor inhibits adrenergic and purinergic neurotransmission in the rabbit isolated vas deferens.
Topics: Adenosine Triphosphate; Animals; Atrial Natriuretic Factor; Electric Stimulation; In Vitro Technique | 1989 |
Paf-induced release of spasmogens from guinea-pig lungs.
Topics: Animals; Aspirin; Bronchi; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Ind | 1989 |
Role of monokines in altering receptor and non-receptor mediated vascular contraction in sepsis.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Endothelium, Vascular; In Vitro Techniques; Indomethacin; I | 1989 |
Evidence for two populations of 5-hydroxytryptamine receptors in dog basilar artery.
Topics: Animals; Basilar Artery; Cocaine; Dogs; In Vitro Techniques; Indomethacin; Ketanserin; Muscle Contra | 1989 |
Failure of non-adrenergic transmission in the rat vas deferens.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Electric Stimulation; Epididymis; | 1989 |
Antihypertensive properties of linoleic acid and fish oil omega-3 fatty acids independent of the prostaglandin system.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Eicosapentaenoic Acid; Fish Oils; Hyperten | 1989 |
The different contributions of prostaglandins (E1, E2, F2 alpha, D2) to the tone and neurogenic response of bovine iris sphincter muscle.
Topics: Animals; Carbachol; Cattle; Electric Stimulation; In Vitro Techniques; Indomethacin; Iris; Muscle Co | 1989 |
Short-term desensitization of prostaglandin F2 alpha receptors increases cyclic AMP formation and reduces inositol phosphates accumulation and contraction in the bovine iris sphincter.
Topics: Animals; Cattle; Cyclic AMP; Diglycerides; Dinoprost; In Vitro Techniques; Indomethacin; Inositol Ph | 1989 |
Analysis of the beta-adrenoceptor mediated inhibition of IgG1 and IgE dependent guinea-pig anaphylactic tracheal smooth muscle contraction.
Topics: Anaphylaxis; Animals; Chromones; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-ace | 1989 |
Prostaglandins and neurotransmission at the guinea pig and rabbit urinary bladder.
Topics: Acetylcholine; Action Potentials; Animals; Electric Stimulation; Guinea Pigs; Indomethacin; Membrane | 1989 |
Effects of verapamil on the contractions of guinea-pig tracheal muscle induced by Ca, Sr and Ba.
Topics: Animals; Barium; Calcium; Carbachol; Dinoprost; Guinea Pigs; In Vitro Techniques; Indomethacin; Ion | 1985 |
Some properties of calcium-induced contraction in the isolated human and guinea-pig tracheal smooth muscle.
Topics: Aged; Animals; Aspirin; Calcium; Chromones; Female; Guinea Pigs; Humans; Indomethacin; Ion Channels; | 1985 |
In vitro reactivity of dog cavernous carotid artery to stretch and adrenergic stimulation.
Topics: Acetylcholine; Animals; Aspirin; Carotid Artery, Internal; Dogs; Electric Stimulation; Endothelium, | 1989 |
The role of protein kinase-C in sensitization and antigen response of airway smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Antibody Specificity; Antigens; C | 1989 |
The spontaneous electrical and mechanical activity of human bronchial smooth muscle: its modulation by drugs.
Topics: Adult; Aged; Aged, 80 and over; Atropine; Bronchi; Chromones; Electric Stimulation; Electrophysiolog | 1989 |
[Arg8]vasopressin-induced contractions of rabbit urinary bladder smooth muscle.
Topics: Animals; Arginine Vasopressin; Calcium; Carbachol; In Vitro Techniques; Indomethacin; Male; Muscle C | 1989 |
Vasoconstrictor response of large cerebral arteries of cats to endothelin, an endothelium-derived vasoactive peptide.
Topics: Animals; Calcium; Cats; Cerebral Arteries; Endothelins; Female; In Vitro Techniques; Indomethacin; M | 1989 |
The activity of peptides of the endothelin family in various mammalian smooth muscle preparations.
Topics: Animals; Electric Stimulation; Endothelins; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; | 1989 |
Role of arachidonic acid metabolites in hypoxic contractions of isolated porcine pulmonary artery and vein.
Topics: Animals; Arachidonic Acids; Chromones; Histamine; Hypoxia; In Vitro Techniques; Indomethacin; Muscle | 1989 |
Endothelium-dependent relaxation of the rat renal artery caused by activation of histamine H1-receptors.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Female; Histamine; In Vitro Techniques; Indomethacin; | 1989 |
Effects of hypoxia on the pharmacological responsiveness of isolated coronary artery rings from the sheep.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Coronary Vessels; Hypox | 1989 |
Modification by indomethacin of airway contractile responses in normal and sensitized guinea-pigs.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Muscle Contraction; Muscle, Smo | 1989 |
Histamine receptors in the smooth muscle of human internal mammary artery and saphenous vein.
Topics: Diuretics; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Humans; Indomethacin; | 1989 |
Cholecystokinin-octapeptide constricts guinea-pig and human airways.
Topics: Animals; Benzodiazepinones; Bronchi; Devazepide; Electric Stimulation; Epithelium; Glycopeptides; Gu | 1989 |
Human isolated bronchial muscle preparations from asthmatic patients: effects of indomethacin and contractile agonists.
Topics: Acetylcholine; Asthma; Bronchi; Dinoprost; Dinoprostone; Histamine; Humans; In Vitro Techniques; Ind | 1989 |
Low calcium and calcium antagonists potentiate the contraction of guinea-pig vas deferens induced by ATP: a permissive role for P2-purinoceptors.
Topics: Adenosine Triphosphate; Animals; Atropine; Calcium; Calcium Channel Blockers; Guinea Pigs; Hexametho | 1989 |
Inhibition of antigen-induced contraction of guinea pig trachea by ICI 198,615.
Topics: Animals; Antigens; Guinea Pigs; In Vitro Techniques; Indazoles; Indomethacin; Leukotrienes; Lipoxyge | 1989 |
Mechanisms involved in the action of prostaglandins as modulators of neurotransmission.
Topics: Acetylcholine; Adenosine; Animals; Blood Pressure; Dilazep; Electric Stimulation; Female; Heart Rate | 1989 |
Wy-48,252 (1,1,1-trifluoro-N-[3-(2-quinolinylmethoxy)phenyl]methane sulfonamide) an orally active leukotriene D4 antagonist: pharmacological characterization in vitro and in vivo in the guinea pig.
Topics: Animals; Bronchi; Capillary Permeability; Cysteine; Guinea Pigs; Histamine; Hydroxyquinolines; In Vi | 1989 |
Interleukin 1 inhibits contraction of vascular smooth muscle.
Topics: Animals; Cycloheximide; Indomethacin; Interleukin-1; Male; Muscle Contraction; Muscle, Smooth, Vascu | 1989 |
Contractile actions of epidermal growth factor-urogastrone in isolated smooth muscle preparations from guinea pig stomach: structure-activity relationships and comparison with the effects of human transforming growth factor-alpha.
Topics: Animals; Dose-Response Relationship, Drug; Epidermal Growth Factor; Guinea Pigs; In Vitro Techniques | 1989 |
Epidermal growth factor-urogastrone (EGF-URO) causes contraction of porcine coronary arterial strips: inhibition by indomethacin.
Topics: Animals; Calcium; Coronary Vessels; Dinoprost; Epidermal Growth Factor; In Vitro Techniques; Indomet | 1989 |
Effects of antigen on tracheal circulation and smooth muscle in sheep of different ages.
Topics: Age Factors; Animals; Antigens, Helminth; Ascaris; Asthma; Female; Indomethacin; Male; Muscle Contra | 1989 |
Temperature-dependent specific desensitization in the rat anococcygeus muscle to angiotensin II.
Topics: Angiotensin II; Animals; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscles; Norep | 1989 |
Characterization of an endothelial 5-hydroxytryptamine (5-HT) receptor mediating relaxation of the porcine coronary artery.
Topics: Animals; Citalopram; Coronary Vessels; Corticosterone; Endothelium, Vascular; Gossypol; In Vitro Tec | 1989 |
Effects of endogenous and exogenous prostaglandin in neurotransmission in canine trachea.
Topics: Acetylcholine; Animals; Atropine; Dinoprostone; Dogs; Female; Guanethidine; In Vitro Techniques; Ind | 1987 |
Influence of eicosapentaenoic acid on noradrenaline and angiotensin-induced contractions of the rabbit aorta: mode of action.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Eicosapentaenoic Acid; In Vitro Techniques; Indomethacin; | 1987 |
Mechanisms of endothelium-dependent vascular smooth muscle relaxation elicited by bradykinin and VIP.
Topics: Animals; Bradykinin; Cattle; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Indomethacin; Methylene | 1987 |
Endothelium-dependent modulation of angiotensin II-induced contraction in blood vessels.
Topics: Angiotensin II; Animals; Cattle; Endothelium, Vascular; Hemoglobins; Hydrolysis; In Vitro Techniques | 1988 |
Indications for P2-purinoceptor subtypes in guinea pig smooth muscle.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atropine; C | 1988 |
Physio-pharmacology of erectile process in man.
Topics: Animals; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Norepinep | 1988 |
Modulation of cholinergic neurotransmission by vasoactive intestinal peptide in ferret trachea.
Topics: Acetylcholine; Animals; Ferrets; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smoo | 1988 |
Leukotriene and anti-IgE induced contractions of human isolated trachea: studies with leukotriene receptor antagonists and a novel 5-lipoxygenase inhibitor.
Topics: Animals; Antibodies, Anti-Idiotypic; Arachidonate Lipoxygenases; Atropine; Benzofurans; Chromones; G | 1988 |
Release of prostaglandins during the contraction of rat aorta induced by ouabain and K+-free solution.
Topics: Animals; Aorta, Thoracic; Calcium; In Vitro Techniques; Indomethacin; Ion Exchange; Male; Muscle Con | 1988 |
Postjunctional effects of mianserin and its metabolites on the rat isolated anococcygeus muscle.
Topics: Animals; Dibenzazepines; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Male; | 1985 |
Contraction induced by (-)-tartaric acid on rat isolated gastric fundus and its inhibition with indomethacin.
Topics: Acetylcholine; Animals; Atropine; Dinoprostone; Female; Gastric Fundus; Histamine; In Vitro Techniqu | 1985 |
Beta agonist-induced desensitization in pig bronchus.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Airway Resistance; Animals; Bronchi; Colforsi | 1986 |
Characteristics of neuro-effector transmission in the smooth muscle layer of dog bronchiole and modifications by autacoids.
Topics: Action Potentials; Animals; Atropine; Autacoids; Bronchi; Dogs; Female; Histamine Antagonists; In Vi | 1986 |
The contractile action of palytoxin in the isolated rabbit urinary bladder.
Topics: Acrylamides; Animals; Arachidonic Acid; Arachidonic Acids; Cnidarian Venoms; In Vitro Techniques; In | 1986 |
Menstrual cycle and sensitivity of human fallopian tube to prostaglandins.
Topics: Adult; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprost; D | 1986 |
Evidence against VIP as the inhibitory transmitter in non-adrenergic, non-cholinergic nerves supplying the longitudinal muscle of the mouse colon.
Topics: Adenylyl Cyclases; Animals; Colon; In Vitro Techniques; Indomethacin; Mice; Muscle Contraction; Musc | 1986 |
Contractile effects of jellyfish toxin extracted from Carybdea rastonii on isolated rabbit aorta.
Topics: Animals; Aorta, Thoracic; Chlorpromazine; Cnidarian Venoms; Drug Interactions; In Vitro Techniques; | 1986 |
Parasympathetic involvement in PAF-induced contraction in canine trachealis in vivo.
Topics: Animals; Atropine; Biomechanical Phenomena; Chlorpheniramine; Dogs; Dose-Response Relationship, Drug | 1987 |
Contractile and relaxant effects of jellyfish toxin on the vascular and intestinal tissues.
Topics: Animals; Aspirin; Cnidaria; Cnidarian Venoms; Endothelium; In Vitro Techniques; Indomethacin; Male; | 1987 |
Gastric antisecretory and antiulcer effects of WHR1582A, a compound exerting alpha-2 adrenoceptor agonist activity.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Ulcer Agents; Aspirin; Carbachol; Clonidine; Cysteamine; Di | 1987 |
Modulation of rabbit airway smooth muscle responsiveness by respiratory epithelium. Involvement of an inhibitory metabolite of arachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bethanechol; Bethanechol Compounds; Bronchi; Epitheliu | 1987 |
Potentiation of the responses to transmural nerve stimulation by alpha-agonists: a possible role in vivo.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dogs; Electric Stimulation; Epinephrine; Indomethacin | 1987 |
Effect of neurotensin on the smooth muscle of the chicken crop.
Topics: Animals; Atropine; Chickens; Dose-Response Relationship, Drug; Indomethacin; Muscle Contraction; Mus | 1987 |
Contractile activity of calcitonin gene-related peptide on pulmonary tissues.
Topics: Animals; Calcitonin Gene-Related Peptide; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Musc | 1988 |
Production of leukotrienes from mouse peritoneal macrophages by treatment with a neutral subfraction of bakers' yeast mannan.
Topics: Animals; Autacoids; Chromatography, High Pressure Liquid; Dexamethasone; Guinea Pigs; Indomethacin; | 1988 |
Inhibition of cysteinyl-leukotriene production by azelastine and its biological significance.
Topics: Animals; Antigens; Arachidonic Acid; Arachidonic Acids; Bronchi; Guinea Pigs; Histamine H1 Antagonis | 1988 |
Influence of prostaglandins on electrical and mechanical activities of gastric muscles of Bufo marinus.
Topics: Acetylcholine; Animals; Bufonidae; Dinoprostone; Drug Synergism; Electric Stimulation; In Vitro Tech | 1988 |
Prostaglandins augment muscarinic responses in the rabbit cecum.
Topics: Acetylcholine; Animals; Apamin; Atropine; Cecum; Dinoprost; Dinoprostone; Electric Stimulation; Evok | 1989 |
[Effect of indomethacin on the sensitivity of the adreno- and cholinoreceptors in the cardiovascular system].
Topics: Abdominal Muscles; Animals; Cardiovascular System; Cats; Heart; Indomethacin; Muscle Contraction; Ra | 1986 |
Differential effect of vasoactive intestinal peptide on contractions induced by leukotriene D4, histamine, and acetylcholine in guinea pig lung parenchyma in vitro.
Topics: Acetylcholine; Albuterol; Animals; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Lung; | 1987 |
Two distinct effects of oxygen on vascular tone in isolated porcine coronary arteries.
Topics: Animals; Aspirin; Coronary Vessels; Histamine Antagonists; Indomethacin; Isoproterenol; Meclofenamic | 1985 |
Inhibitors of prostaglandin synthesis augment beta-adrenergic responsiveness in canine coronary arteries.
Topics: Acetylcholine; Animals; Coronary Vessels; Dinoprost; Dogs; Electric Stimulation; Indomethacin; Isopr | 1985 |
Evidence for oxytocin receptors in the urinary bladder of the rabbit.
Topics: Animals; Cell Membrane; Indomethacin; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Oxytocin; | 1985 |
Dual effect of GABA on the contractile activity of the guinea-pig isolated urinary bladder.
Topics: Acetylcholine; Animals; Baclofen; Dimethylphenylpiperazinium Iodide; Drug Interactions; gamma-Aminob | 1985 |
Pharmacological modulation of responses of guinea-pig airways contracted with arachidonic acid.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Catechols; Chromones; Epop | 1985 |
Dual inhibitory action of ATP on adrenergic neuroeffector transmission in rabbit pulmonary artery.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; | 1985 |
Modulation of cholinergic neurotransmission in canine airways by thromboxane mimetic U46619.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Bronchi; | 1985 |
Enhancement of plasma levels of biologically active leukotriene B compounds during anaphylaxis in guinea pigs pretreated by indomethacin or by a fish oil-enriched diet.
Topics: Anaphylaxis; Animals; Cattle; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Dietary F | 1986 |
Eicosonoid metabolism and beta-adrenergic mechanisms in coronary arterial smooth muscle: potential compartmentation of cAMP.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Coronary Vessels; Cyclic AMP; Indomethacin; Is | 1986 |
Characterization of prostanoid relaxant/inhibitory receptors (psi) using a highly selective agonist, TR4979.
Topics: Alprostadil; Animals; Cats; Chickens; Colon; Dose-Response Relationship, Drug; Female; Guinea Pigs; | 1986 |
Methacholine sensitivity and cAMP protein kinase in tracheal smooth muscle.
Topics: Animals; Cyclic AMP; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Drug Resistance; In Vitro T | 1986 |
Biochemical and pharmacological analysis of 2-[(2-dimethylaminobenzyl)sulfinyl] benzimidazole (NC-1300), a new proton pump inhibitor.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetylcholine; Adenosine Triphosphatases; Animals; Anti-Ulc | 1986 |
Effects of sodium vanadate on various types of vascular smooth muscles.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo | 1986 |
Generation and transmission of ovine ureteral contractions, with special reference to prostaglandins.
Topics: Animals; Dinoprost; Indomethacin; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Prosta | 1986 |
Induction of vascular relaxation by hydroperoxides.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Chlorobenzoates; Endothelium; Hydroxide | 1986 |
Endothelium-dependent modulation of cGMP levels and intrinsic smooth muscle tone in isolated bovine intrapulmonary artery and vein.
Topics: Animals; Cattle; Cyclic AMP; Cyclic GMP; Endothelium; In Vitro Techniques; Indomethacin; Methylene B | 1987 |
Antagonism of antigen-induced contraction of isolated guinea-pig trachea by 5-lipoxygenase inhibitors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Anima | 1986 |
Modulation of in vitro anaphylaxis of guinea-pig isolated tracheal segments by azelastine, inhibitors of arachidonic acid metabolism and selected antiallergic drugs.
Topics: Airway Resistance; Anaphylaxis; Animals; Antigens; Arachidonic Acid; Arachidonic Acids; Guinea Pigs; | 1986 |
Effects of prostaglandin I2 synthesized in the endothelium and in the smooth muscle on mechanical properties of the canine thoracic aorta.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Animals; Aorta, Thoracic; Calcimycin; Dogs; Endothelium | 1986 |
Cyclo-oxygenase blockers influence the effects of 15-lipoxygenase metabolites of arachidonic acid in isolated canine blood vessels.
Topics: Animals; Arachidonate 15-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acids; Aspirin; Cyclo | 1986 |
Modulation of smooth muscle responses by serine proteases and related enzymes.
Topics: Animals; Biological Assay; Blood Pressure; Endopeptidases; Factor IX; Factor IXa; Factor VII; Factor | 1986 |
Pharmacological characterization of airway smooth muscle responses to antigen in ascaris-sensitive dogs.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Airway Resistance; Animals; Antigens, Helminth; Arac | 1986 |
Effects of leukotriene D4 and antagonists of arachidonic acid metabolism and calcium entry on guinea pig tracheal muscle responsiveness.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetylcholine; Animals; Arachidonic Ac | 1986 |
Antagonism by ETYA of the effects of leukotrienes on ileum and lung parenchymal strips independent of effects on arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Chromones; Fatty Acid | 1986 |
Extracellular calcium dependence of contraction and endothelium-dependent relaxation varies along the length of the aorta and its branches.
Topics: Acetylcholine; Animals; Aorta; Calcimycin; Calcium; Diltiazem; Endothelium; Extracellular Space; Gal | 1987 |
Feedback control of arterial smooth muscle tone: the role of prostacyclin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase Inhibitors; Epoprostenol; Feedback; In Vitro T | 1986 |
Arachidonic acid-induced endothelial-dependent relaxations of canine coronary arteries: contribution of a cytochrome P-450-dependent pathway.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoflavones; beta-Naphthoflavone; Coronary Vessels; | 1987 |
Arachidonic acid and pulmonary function in heart-lung-preparation of guinea-pig: modulation by PCO2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arach | 1987 |
Pharmacological comparison of L-serine borate and glutathione as inhibitors of metabolism of LTC4 to LTD4 by the isolated guinea pig trachea.
Topics: Animals; Borates; Glutathione; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contract | 1987 |
Interaction between chloroquine and indomethacin in airways smooth muscle in vivo.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bronchi; Chloroquine; Female; Guinea Pigs; Histamine; | 1987 |
Impaired endothelium-dependent relaxations in rabbits subjected to aortic coarctation hypertension.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Coarctation; Calcimycin; Carotid A | 1987 |
Relaxation of guinea-pig tracheal smooth muscle to arachidonate is converted to contraction following epithelium removal.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Epithelium; Guinea Pigs; In Vitro Techniques; Indometh | 1987 |
Arachidonic acid metabolites and airway epithelium-dependent relaxant factor.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non | 1987 |
Release of eicosanoids from human synovial tissue and the effect of anti-inflammatory drugs.
Topics: Aminosalicylic Acids; Animals; Calcimycin; Chromones; Guinea Pigs; Humans; In Vitro Techniques; Indo | 1987 |
Prostaglandin F2 stimulates the generation of lipoxygenase products in guinea pig isolated trachea.
Topics: Animals; Chromones; Guinea Pigs; In Vitro Techniques; Indomethacin; Lipoxygenase; Male; Masoprocol; | 1987 |
Effects of indomethacin and prostaglandins on the dog iris sphincter and dilator muscles.
Topics: Animals; Atropine; Dogs; Egtazic Acid; Female; Indomethacin; Iris; Male; Membrane Potentials; Muscle | 1988 |
Possible prostacyclin involvement on disparate tonic responses to "in vitro" norepinephrine in circular and in longitudinal preparations from rat thoracic aorta.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Dose-Re | 1987 |
The effect of nifedipine on spontaneous, drug-induced and reflexly-activated contractions of the rat urinary bladder: evidence for the participation of an intracellular calcium store to micturition contraction.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carbachol; Edetic Aci | 1988 |
A possible role for prostaglandins in the expression of morphine dependence in guinea-pig isolated ileum.
Topics: Alprostadil; Animals; Cyclooxygenase Inhibitors; Guinea Pigs; Ileum; In Vitro Techniques; Indomethac | 1988 |
Effect of metabolic products of muscular contraction on discharge of group III and IV afferents.
Topics: 2-Chloroadenosine; Adenosine; Afferent Pathways; Animals; Arachidonic Acid; Arachidonic Acids; Blood | 1988 |
Effect of Desmodium adscendens fractions on antigen- and arachidonic acid-induced contractions of guinea pig airways.
Topics: 1-Butanol; Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Butanols; Chemical Fractionati | 1988 |
Inhibitors of cyclooxygenase augment serotonergic responsiveness in canine coronary arteries.
Topics: Animals; Coronary Vessels; Cyclooxygenase Inhibitors; Dinoprost; Dogs; Endothelium, Vascular; Female | 1988 |
The relaxant and spasmogenic effects of some xanthine derivatives acting on guinea-pig isolated trachealis muscle.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Colforsin; Egtazic Acid; Female; Guinea Pigs; In Vitro Te | 1988 |
Evidence that the histamine sensitivity and responsiveness of guinea-pig isolated trachea are modulated by epithelial prostaglandin E2 production.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Epithelium; Histamine; In Vitro Techniqu | 1988 |
Mucosal inhibition of cholinergic contractions in ferret trachea can be transferred between organ baths.
Topics: Animals; Biological Factors; Cholinergic Fibers; Cyclooxygenase Inhibitors; Electric Stimulation; Fe | 1988 |
Contraction of guinea pig trachea by epidermal growth factor--urogastrone.
Topics: Animals; Calcium; Egtazic Acid; Epidermal Growth Factor; Epithelium; Guinea Pigs; In Vitro Technique | 1988 |
Potentiation by phenolphthalein of the responses of guinea-pig ileum and rat stomach strip to PGE2 and other agonists.
Topics: Animals; Calcium; Dinoprostone; Drug Synergism; Guinea Pigs; Ileum; In Vitro Techniques; Indomethaci | 1988 |
Effect of pharmacological agents on the activity of the circular and longitudinal smooth muscle layers of human fallopian tube ampullar segments.
Topics: Adult; Dinoprost; Fallopian Tubes; Female; Humans; In Vitro Techniques; Indomethacin; Isoproterenol; | 1988 |
Histamine tachyphylaxis in canine airways despite prostaglandin synthesis inhibition.
Topics: Airway Resistance; Animals; Dogs; Histamine; In Vitro Techniques; Indomethacin; Meclofenamic Acid; M | 1988 |
Inhibitory effects of a lipoxygenase inhibitor nordihydroguaiaretic acid on antagonism of leukotriene C4-induced contractions of isolated guinea-pig trachea.
Topics: Animals; Catechols; Chromones; Guinea Pigs; In Vitro Techniques; Indomethacin; Masoprocol; Muscle Co | 1988 |
Relaxation by prostacyclin (PGI2) of human, dog and rabbit femoral artery strips. Interspecies difference.
Topics: Animals; Dinoprost; Dogs; Drug Synergism; Femoral Artery; Humans; In Vitro Techniques; Indomethacin; | 1988 |
Possible mechanisms related to contraction of the bovine iris sphincter in the presence of acetylcholine and carbachol.
Topics: Acetylcholine; Animals; Carbachol; Cattle; Dose-Response Relationship, Drug; Indomethacin; Iris; Mus | 1988 |
The spasmogenic effect of caffeine in trachealis isolated from control and actively sensitized guinea-pigs.
Topics: Animals; Caffeine; Calcium; Dantrolene; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Muscle, | 1988 |
Distinctive actions of epidermal growth factor-urogastrone in isolated smooth muscle preparations from guinea pig stomach: differential inhibition by indomethacin.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Epidermal Growth Factor; | 1988 |
Inhibition by anti-inflammatory agents of contraction induced by epidermal growth factor-urogastrone in isolated longitudinal smooth muscle strips from guinea-pig stomach.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Auranofin; Cycloheximide; Dexamethasone; | 1988 |
Effect of endogenous prostaglandins on acetylcholine release from dog trachealis muscle.
Topics: Acetylcholine; Animals; Dinoprostone; Dogs; Electric Stimulation; Epoprostenol; In Vitro Techniques; | 1987 |
Study of platelet activating factor and its antagonists on rat colon strip with a new method avoiding tachyphylaxis.
Topics: Animals; Atropine; Chlorpheniramine; Chromones; Colon; In Vitro Techniques; Indomethacin; Male; Meth | 1988 |
Regional differences in the mechanical properties of rabbit airway smooth muscle.
Topics: Acetylcholine; Animals; Asthma; Bronchi; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle | 1988 |
The action of the prostaglandins on isolated human ureteric smooth muscle.
Topics: Diclofenac; Dinoprost; Dinoprostone; Humans; In Vitro Techniques; Indomethacin; Membrane Potentials; | 1988 |
Vasopressin causes endothelium-independent contraction of the rat arteries.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arteries; Endothelium, Vascular; Female; In Vitro Technique | 1987 |
The long-lasting contraction induced by transmural stimulation in the longitudinal muscle of the guinea-pig gastric corpus.
Topics: Adenosine Triphosphate; Animals; Atropine; Electric Stimulation; Female; Guinea Pigs; In Vitro Techn | 1987 |
Different time courses of bovine iris sphincter and dilator muscles after stimulation.
Topics: Animals; Cattle; Electric Stimulation; Electromyography; In Vitro Techniques; Indomethacin; Iris; Mu | 1987 |
Effect of diabetes on vascular smooth muscle function in normotensive and spontaneously hypertensive rat mesenteric artery.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Dr | 1987 |
Involvement of intramural prostaglandin E2 in prenatal patency of the lamb ductus arteriosus.
Topics: Animals; Carbon Monoxide; Dinoprostone; Ductus Arteriosus; Female; Fetus; Glutathione; Indomethacin; | 1986 |
Responsiveness of rat vas deferens and stomach smooth muscles after treatment with indomethacin.
Topics: Acetylcholine; Animals; Dinoprost; Dinoprostone; Electric Stimulation; In Vitro Techniques; Indometh | 1986 |
Angiotensin peptides and prostaglandin E2 synthesis: modulation of neurogenic responses in the rabbit vas deferens.
Topics: Adenosine Triphosphate; Angiotensin II; Angiotensin III; Animals; Dinoprostone; Electric Stimulation | 1986 |
Prostaglandin D2 (PGD2) potentiates cholinergic responsiveness in guinea-pig trachea.
Topics: Acetylcholine; Animals; Dinoprost; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indometha | 1986 |
Histamine contraction of isolated human airway muscle preparations: role of prostaglandins.
Topics: Bronchi; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Histamine; Humans; Indomethacin; | 1986 |
Muscle tone and drug sensitivity of isolated bovine iris sphincter are enhanced at low temperatures.
Topics: Animals; Carbachol; Cattle; Dinoprostone; Indomethacin; Iris; Muscle Contraction; Muscle Tonus; Pros | 1987 |
Endothelium-dependent relaxations in human arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Adolescent; Adult; Aged; Arteries; Dinoprost; Endothelium; Hum | 1987 |
Contribution of prostaglandin E2 to bradykinin-induced contraction in rabbit urinary detrusor.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Arachidonic Acids; Bradykinin; Caffeic Acids; Dinopr | 1987 |
Platelet-activating factor-acether-induced relaxation of guinea pig airway muscle: role of prostaglandin E2 and the epithelium.
Topics: Acetylcholine; Animals; Aspirin; Dinoprostone; Epithelium; Guinea Pigs; Histamine; In Vitro Techniqu | 1987 |
The effect of prostaglandin synthesis inhibition on motility of the sheep ureter.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Diclofenac; Dinoprost; Humans; Indomethacin; Muscle Contracti | 1987 |
Endothelium-derived relaxing factor is a selective relaxant of vascular smooth muscle.
Topics: Animals; Aorta; Biological Products; Cattle; Cells, Cultured; Endothelium, Vascular; Guinea Pigs; In | 1987 |
Biological profile of a bioactive aortic substance (BAS), released by vessel rings from indomethacin-treated rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Abdominal; Aorta, Thoracic; Culture Media; Epoprosteno | 1986 |
Prostaglandins contribute to cardiovascular reflexes evoked by static muscular contraction.
Topics: Animals; Captopril; Cardiovascular Physiological Phenomena; Cats; Dinoprostone; Female; Hemodynamics | 1986 |
Effect of macrophage stimulation on parasympathetic airway contraction in dogs.
Topics: Animals; Asthma; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Dogs; Electric Stimulation; Fatty | 1987 |
Effects of milrinone on contractility of the rat diaphragm in vitro.
Topics: Animals; Diaphragm; Dose-Response Relationship, Drug; Electric Stimulation; Indomethacin; Isometric | 1987 |
Actions of platelet-activating factor in the coronary circulation of the guinea pig in vitro.
Topics: Animals; Blood Pressure; Chromones; Coronary Circulation; Guinea Pigs; In Vitro Techniques; Indometh | 1987 |
Differential effects of epithelium removal on the responsiveness of guinea-pig tracheal smooth muscle to bronchoconstrictors.
Topics: Animals; Asthma; Bronchi; Epithelium; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle C | 1987 |
Pre- and postsynaptic bradykinin responses in the rat vas deferens: asymmetric distribution of the postsynaptic effect.
Topics: Animals; Bradykinin; Drug Interactions; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; | 1986 |
Pharmacological analysis of rebound excitation in large intestine of piebald mouse model for Hirschsprung's disease.
Topics: Animals; Atropine; Dimethylphenylpiperazinium Iodide; Guanethidine; Hirschsprung Disease; Indomethac | 1986 |
Inhibition by indomethacin of naloxone-precipitated opiate withdrawal contraction in isolated guinea pig myenteric plexus-longitudinal muscle preparation.
Topics: Acetylcholine; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Morphine Depend | 1986 |
Suppression by 5'-methylthioadenosine of histamine or leukotriene-induced contraction in isolated guinea pig tracheal rings.
Topics: Adenosine; Animals; Deoxyadenosines; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Hi | 1986 |
Physiological and pharmacological characterization of an in vitro vagus nerve-trachea preparation from guinea-pig.
Topics: Animals; Atropine; Carbachol; Electric Stimulation; Guinea Pigs; Hexamethonium Compounds; In Vitro T | 1986 |
Mechanisms of histamine-induced relaxation in isolated monkey and dog coronary arteries.
Topics: Animals; Benzoquinones; Chlorpheniramine; Cimetidine; Coronary Vessels; Dogs; Female; Histamine; Ind | 1986 |
Relation between duodenal alkaline secretion and motility in fasted and sham-fed dogs.
Topics: Action Potentials; Animals; Atropine; Bicarbonates; Dogs; Duodenum; Fasting; Food; Gastrins; Gastroi | 1986 |
In vitro muscle contractures induced by halothane and suxamethonium. I: The rat diaphragm.
Topics: Animals; Dantrolene; Diaphragm; Drug Synergism; Halothane; In Vitro Techniques; Indomethacin; Male; | 1986 |
In vitro muscle contractures induced by halothane and suxamethonium. II: Human skeletal muscle from normal and malignant hyperthermia susceptible patients.
Topics: Disease Susceptibility; Fatty Acids, Nonesterified; Halothane; Humans; In Vitro Techniques; Indometh | 1986 |
Endothelium-dependent relaxation of human pulmonary arteries.
Topics: Acetylcholine; Adenosine Triphosphate; Endothelium; Humans; Indomethacin; Muscle Contraction; Muscle | 1987 |
Effect of cooling on vascular smooth muscle from the thirteen-lined ground squirrel.
Topics: Animals; Cold Temperature; Hibernation; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscl | 1987 |
Smooth muscle contractility and changes in histaminergic mechanisms in the pig trachea during development.
Topics: Animals; Connective Tissue; Histamine; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle | 1986 |
Action of different agonists and antagonists of the cholinergic system on the rat lower esophageal sphincter.
Topics: Animals; Benzodiazepinones; Calcium; Cold Temperature; Dimethylphenylpiperazinium Iodide; Esophagoga | 1985 |
Leukotriene D4 and phospholipase A2 release thromboxane A2 of different origin in the guinea pig lung parenchymal strip.
Topics: Animals; Chloroquine; Guinea Pigs; Indomethacin; Lung; Muscle Contraction; Phospholipases; Phospholi | 1985 |
Central control of intestinal motility by prostaglandins: a mediator of the actions of several peptides in rats and dogs.
Topics: Action Potentials; Animals; Calcitonin; Dinoprostone; Dogs; Electromyography; Enkephalin, Methionine | 1985 |
Augmentation of parasympathetic contraction in tracheal and bronchial airways by PGF2 alpha in situ.
Topics: Animals; Bronchi; Dinoprost; Dogs; Electric Stimulation; Female; Indomethacin; Male; Muscle Contract | 1985 |
Effect of prostaglandin E2 on the electrical activity of cat isolated stomach muscle.
Topics: Action Potentials; Animals; Cats; Dinoprostone; Electromyography; Female; In Vitro Techniques; Indom | 1985 |
Effects of prostaglandin F2 alpha and indomethacin on the contractile activity of different compartments of the complex stomach.
Topics: Abomasum; Acetylcholine; Animals; Dinoprost; Gallopamil; Guinea Pigs; In Vitro Techniques; Indometha | 1985 |
Motility of the human ureter, with special reference to the effect of indomethacin.
Topics: Dinoprost; Dinoprostone; Humans; In Vitro Techniques; Indomethacin; Kidney Diseases; Muscle Contract | 1985 |
Vascular actions of epidermal growth factor-urogastrone: possible relationship to prostaglandin production.
Topics: Alprostadil; Animals; Dinoprost; Drug Interactions; Epidermal Growth Factor; In Vitro Techniques; In | 1985 |
Role of endothelium in the contractions induced by norepinephrine and clonidine in rat aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Clonidine; Endothelium; In Vitro Techniques; Indomethacin; | 1985 |
Role of prostaglandins in control of intestinal motility.
Topics: Animals; Dinoprost; Dinoprostone; Dogs; Eating; Electrodes, Implanted; Epoprostenol; Gastrointestina | 1985 |
Endogenous prostaglandins modulate histamine-induced contraction in canine tracheal smooth muscle.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Chromatography, High Pressure Liquid; Dogs; Epoprost | 1985 |
Indomethacin and meclofenamate potentiation of skeletal muscle active hyperemia.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dogs; Hyperemia; Indomethacin; Male; Meclofenamic Acid | 1985 |
Influence of cyclooxygenase inhibitors and arachidonic acid on contractile activity of the human Fallopian tube.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adult; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibito | 1985 |
Effect of indomethacin on airway contraction and the release of LTC4-like material.
Topics: Airway Resistance; Animals; Arachidonic Acid; Arachidonic Acids; Guinea Pigs; In Vitro Techniques; I | 1985 |
Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Aci | 1985 |
Pharmacological modulation of responses of guinea-pig airways contracted with antigen and calcium ionophore A23187.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate Lipoxygenases; C | 1985 |
Prostaglandin synthetase inhibition of renal pelvic smooth muscle in the rabbit.
Topics: Animals; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Dose-Response Relationship, | 1985 |
The effect of cyclooxygenase inhibitors on the low filling rate cystometrogram in urethane anesthetized rats.
Topics: Anesthesia; Animals; Cyclooxygenase Inhibitors; Indomethacin; Ketoprofen; Male; Muscle Contraction; | 1985 |
Dopamine-induced potentiation of the contractile response to arachidonic acid in guinea-pig aorta.
Topics: Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Aspirin; Catechols; Corticosterone; Dopamine; D | 1985 |
Ouabain inhibits endothelium-dependent relaxations to arachidonic acid in canine coronary arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Coronary Vessels | 1985 |
Alterations of arachidonic acid metabolism modulate adenosine relaxation in isolated coronary arteries.
Topics: Adenosine; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Coronary Vessels; Dogs; Enzyme Inhi | 1985 |
Pharmacological characterization of opossum distal colonic muscularis mucosae in vitro.
Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atropine; Colon; Dose-Respons | 1986 |
Parasympathetic stimulation as a mechanism for platelet-activating factor-induced contractile responses in the lung.
Topics: Acetylcholine; Animals; Atropine; Cholinesterase Inhibitors; Guinea Pigs; In Vitro Techniques; Indom | 1986 |
Respiratory epithelium inhibits bronchial smooth muscle tone.
Topics: Acetylcholine; Animals; Bronchi; Dogs; Electric Stimulation; Epithelium; Female; Histamine; Indometh | 1985 |
Influences of gender and maturation on responses of guinea-pig airway tissues to LTD4.
Topics: Animals; Bronchi; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; | 1985 |
The effect of indomethacin on the motility of isolated sheep ureters.
Topics: Animals; Dose-Response Relationship, Drug; Indomethacin; Muscle Contraction; Muscle, Smooth; Sheep; | 1985 |
Sow (Sus scrofa) follicular fluid: prostaglandin content and effect on the motility of isolated oviducts.
Topics: Animals; Bradykinin; Estrus; Fallopian Tubes; Female; Indomethacin; Muscle Contraction; Ovarian Foll | 1985 |
The neural and non-neural mechanisms involved in urethral activity in rabbits.
Topics: Action Potentials; Animals; Atropine; Guanethidine; In Vitro Techniques; Indomethacin; Male; Membran | 1985 |
Inhibition of gastric motor activity by 16,16-dimethyl prostaglandin E2. A possible explanation of cytoprotection.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Drug Interactions; Ethanol; Gastric Mucosa; Gastrointestina | 1985 |
Effects of ethyl alcohol on phasic and tonic contractions of the proximal stomach.
Topics: Acetylcholine; Animals; Dogs; Dose-Response Relationship, Drug; Ethanol; Female; In Vitro Techniques | 1985 |
Thrombin-elicited contractile responses of aortic smooth muscle.
Topics: Animals; Aorta, Thoracic; Atropine; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; | 1985 |
Attenuation of tracheal smooth muscle contraction by connective tissue.
Topics: Acetylcholine; Animals; Connective Tissue; Histamine; In Vitro Techniques; Indomethacin; Muscle Cont | 1985 |
Turnover rate of interstitial albumin in rat skin and skeletal muscle. Effects of limb movements and motor activity.
Topics: Animals; Capillary Permeability; Extracellular Space; Female; Hindlimb; Indomethacin; Male; Motor Ac | 1985 |
Gradient in excitation-contraction coupling in canine gastric antral circular muscle.
Topics: Animals; Biomechanical Phenomena; Dogs; Female; In Vitro Techniques; Indomethacin; Male; Membrane Po | 1985 |
[Spontaneous contraction of the human saphenous vein and electric stimulation].
Topics: Electric Stimulation; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, | 1985 |
[Effect of hydrogen peroxide on the rat uterine muscle].
Topics: Amitrole; Animals; Calcium; Female; Hydrogen Peroxide; In Vitro Techniques; Indomethacin; Muscle Con | 1985 |
Release of rabbit aorta contracting substance (RCS) and prostaglandins induced by chemical or mechanical stimulation of guinea-pig lungs.
Topics: Angiotensin II; Animals; Aorta; Arachidonic Acids; Arachis; Aspirin; Bradykinin; Guinea Pigs; Half-L | 1973 |
Inhibition by non-steroidal anti-inflammatory agents of the release of rabbit aorta contracting substance and prostaglandins from chopped guinea-pig lungs.
Topics: Animals; Anti-Inflammatory Agents; Aorta; Aspirin; Female; Flufenamic Acid; Guinea Pigs; In Vitro Te | 1974 |
Inhibition by non-steroid anti-inflammatory agents of rabbit aorta contracting activity generated in blood by slow reacting substance C.
Topics: Animals; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Atropine; Autacoids; Colon; Dogs; Fatty | 1974 |
Reversal by prostaglandin E2 of the inhibitory effect of indomethacin on contractions of guinea-pig ileum induced by angiotensin.
Topics: Angiotensin II; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Muscle Contraction; | 1974 |
Actions of putative transmitters in the chicken vagus nerve/oesophagus and Remak nerve/rectum preparations.
Topics: Adenosine; Adenosine Diphosphate; Animals; Animals, Newborn; Chickens; Cyclic AMP; Electric Stimulat | 1974 |
Prostaglandin regulation of airway smooth muscle tone.
Topics: Acetylcholine; Animals; Aspirin; Biological Assay; Female; Guinea Pigs; Histamine; In Vitro Techniqu | 1973 |
Proceedings: Prostaglandin generation maintains the smooth muscle tone of the rabbit isolated jejunum.
Topics: Animals; In Vitro Techniques; Indomethacin; Jejunum; Muscle Contraction; Muscle Tonus; Muscle, Smoot | 1972 |
The effects of arachidonic acid, prostaglandin E2 and prostaglandin F2alpha on the longitudinal stomach strip of the rat.
Topics: Acetylcholine; Animals; Arachidonic Acids; Atropine; Carbachol; Dose-Response Relationship, Drug; Fa | 1973 |
Differentiation of the contractile effects of prostaglandin E2 and the C-terminal octapeptide of cholecystokinin in isolated guinea-pig gallbladder.
Topics: Acetylcholine; Animals; Arachidonic Acids; Cholecystokinin; Depression, Chemical; Dibenzoxazepines; | 1974 |
Studies of prostaglandins and prostaglandin antagonists on bovine pulmonary vein in vitro.
Topics: Acetylcholine; Animals; Aspirin; Bradykinin; Cattle; Depression, Chemical; Diethylcarbamazine; Dose- | 1974 |
The effects of prostaglandins, prostaglandin inhibitors, and oxygen on the closure of the ductus arteriosus, pulmonary arteries and umbilical vessels in vitro.
Topics: Animals; Cattle; Depression, Chemical; Drug Synergism; Ductus Arteriosus; Gestational Age; Humans; I | 1974 |
Effect of anti-inflammatory compounds on actomyosin-adenosinetriphosphate interaction.
Topics: Actomyosin; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; As | 1970 |
Proceedings: Interactions between prostaglandin release and contractile state of isolated splenic strips.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Indomethaci | 1974 |
Interaction of prostaglandins and indomethacin with algesic substances.
Topics: Acetylcholine; Analgesics; Animals; Blood Pressure; Bradykinin; Drug Interactions; Ear; Guinea Pigs; | 1974 |
Production of histamine-like and prostaglandin-like substances from serum incubated with rat, dog, mouse or human tumours.
Topics: Acetates; Animals; Aspirin; Carcinoma, Hepatocellular; Complement System Proteins; Dogs; Histamine; | 1973 |
Some effects of inhibiting endogenous prostaglandin formation on the responses of the cat spleen.
Topics: Angiotensin II; Animals; Cats; Chromatography, Thin Layer; Feedback; Indomethacin; Muscle Contractio | 1973 |
The release of spasmogenic substances from human chopped lung tissue and its inhibition.
Topics: Anaphylaxis; Animals; Aorta; Bordetella pertussis; Bronchi; Cromolyn Sodium; Histamine; Humans; Immu | 1973 |
Application of drug-receptor theories to angiotensin.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Atropine; Cocaine; Diphenhydramine; Dose-Re | 1973 |
Release of prostaglandins from the rabbit renal medulla.
Topics: Angiotensin II; Animals; Atropine; Bradykinin; Carbachol; Diphenhydramine; Dose-Response Relationshi | 1974 |
Proceedings: Influence of postaglandins and oestrus cycle on the spasmodic action of angiotensin II and oxytocin on rat uterus.
Topics: Angiotensin II; Animals; Dose-Response Relationship, Drug; Estrus; Female; In Vitro Techniques; Indo | 1974 |
A modulating role of prostaglandins in contractions of the guinea-pig ileum.
Topics: Acetylcholine; Action Potentials; Adenosine Triphosphate; Angiotensin II; Animals; Atropine; Colon; | 1974 |
Effects of prostaglandin inhibitors on angiotensin, oxytocin and prostaglandin F2 alpha contractile effects on the rat uterus during the oestrous cycle.
Topics: Angiotensin II; Animals; Estrus; Female; In Vitro Techniques; Indomethacin; Muscle Contraction; Oxyt | 1974 |
[Pharmacological study of phenethyl-8-oxa-1-diaza-3,8-spiro(4,5)decanone-2 hydrochloride or fenspiride (JP 428)].
Topics: Anaphylaxis; Anesthesia; Animals; Anti-Inflammatory Agents; Atropine; Autonomic Nervous System; Bron | 1969 |
An overview of chronic recurring headache.
Topics: Acute Disease; Analgesics; Antidepressive Agents; Anxiety; Chronic Disease; Cortisone; Diuretics; Er | 1972 |
Spontaneous and testosterone-induced motility of isolated guinea-pig cauda epididymis.
Topics: Animals; Atropine; Epididymis; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; | 1974 |
The effects of indomethacin and eicosa-5,8,11,14-tetraynoic acid on the response of the rabbit portal vein to electrical stimulation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Electric Stimulation; Fatty Acids, Unsaturated; Guanethidi | 1974 |
Inhibition by sulfhydryl agents of arachidonic acid-induced platelet aggregation and release of potential inflammatory substances.
Topics: Animals; Aorta; Arachidonic Acids; Copper; Depression, Chemical; Dithiothreitol; Glycerol; In Vitro | 1974 |
A release of prostaglandins may be responsible for acute tolerance to norepinephrine infusions.
Topics: Animals; Blood Pressure; Cats; Chickens; Drug Tolerance; Female; Indomethacin; Infusions, Parenteral | 1974 |
Regulation of uterine activity during gestation and parturition in rabbits and rats.
Topics: Animals; Estradiol; Estrogens; Estrone; Female; Indomethacin; Muscle Contraction; Muscle, Smooth; Ov | 1974 |
Prostaglandins reverse inhibition of electrically-induced contractions of guinea pig ileum by morphine, indomethacin and acetylsalicylic acid.
Topics: Animals; Aspirin; Binding, Competitive; Dose-Response Relationship, Drug; Electric Stimulation; Guin | 1973 |
Aspirin and indomethacin prolong parturition in rats: evidence that prostaglandins contribute to expulsion of fetus.
Topics: Administration, Oral; Animals; Aspirin; Biological Assay; Chickens; Chromatography, Thin Layer; Fema | 1972 |
Indomethacin and prostaglandins.
Topics: Animals; Bradykinin; Drug Antagonism; Female; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; | 1972 |
Augmented noradrenaline release following nerve stimulation after inhibition of prostaglandin synthesis with indomethacin.
Topics: Animals; Electric Stimulation; Feedback; Female; Indomethacin; Male; Muscle Contraction; Muscles; My | 1972 |
[Pharmacological studies of niflumic acid, with special reference to the comparison with fenamates. 2. General pharmacological effects].
Topics: Aniline Compounds; Animals; Body Temperature; Digestive System; Electric Stimulation; Electrocardiog | 1972 |
Contractions of rabbit testes in vitro: permissive role of prostaglandins for the actions of calcium and some smooth-muscle stimulating agents.
Topics: Acetylcholine; Animals; Calcium; Depression, Chemical; Dose-Response Relationship, Drug; Drug Synerg | 1973 |
[Effects of metoclopramide and procaine on isolated rat stomach strip].
Topics: Acetylcholine; Animals; Calcium; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techn | 1973 |
The contribution of prostaglandin production to contractions of the isolated uterus of the rat.
Topics: Animals; Chromatography, Gas; Ducks; Epinephrine; Female; In Vitro Techniques; Indomethacin; Muscle | 1973 |
General pharmacological properties of 4,5-diphenyl-2-bis-(2-hydroxyethyl)-aminoxazol (ditazol).
Topics: Amphetamine; Animals; Anti-Inflammatory Agents; Atropine; Blood Pressure; Cats; Chlorpromazine; Etha | 1973 |
[Anti-inflammatory action of N-(2,6-dichlorophenyl)-o-aminophenylacetic acid, its sodium salt, N-(2,6-dichlorophenyl)-anthranilic acid and its sodium salt. 1. On acute inflammation].
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Capillary Permeability; Edema; Electrolytes; Eryth | 1973 |
Vasotropic activity of arachidonic acid peroxide on the isolated murine portal vein and its modification by antiinflammatory substances.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Benzyl Compounds; Blood Vessels; | 1974 |
Effects of indomethacin and prostaglandin F-2-alpha on ovulation and ovarian contractility in the rabbit.
Topics: Animals; Aorta, Abdominal; Chorionic Gonadotropin; Depression, Chemical; Female; Indomethacin; Injec | 1974 |
The effect of indomethacin on the release of prostaglandin E2 and acetylcholine from guinea-pig isolated ileum at rest and during field stimulation.
Topics: Acetylcholine; Animals; Chromatography, Thin Layer; Electric Stimulation; Guinea Pigs; Ileum; In Vit | 1974 |
Studies on the peripheral mode of action of dihydroergotamine in human and canine veins.
Topics: Animals; Atropine; Chlorpheniramine; Dogs; Dose-Response Relationship, Drug; Ergotamine; Femoral Vei | 1974 |
Prostaglandin production contributes to the contractions of the rat isolated uterus.
Topics: Animals; Female; In Vitro Techniques; Indomethacin; Muscle Contraction; Oxytocin; Prostaglandins; Ra | 1972 |
Prostaglandins, oxygen tension and smooth muscle tone.
Topics: Action Potentials; Animals; Chickens; Colon; Glucose; Guinea Pigs; Histamine; In Vitro Techniques; I | 1972 |
The venotropic action of some anti-inflammatory compounds. Observations in the isolated murine portal vein.
Topics: Aminopyrine; Animals; Ergotamine; Glycosides; In Vitro Techniques; Indomethacin; Isoproterenol; Male | 1971 |