Page last updated: 2024-10-29

indomethacin and Metabolic Syndrome

indomethacin has been researched along with Metabolic Syndrome in 3 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harrell, JW1
Schrage, WG1
Pons, Z1
Margalef, M1
Bravo, FI1
Arola-Arnal, A1
Muguerza, B1
Torres, IP1
Hafidi, ME1
Zamora-González, J1
Infante, O1
Chavira, R1
Baños, G1

Trials

1 trial available for indomethacin and Metabolic Syndrome

ArticleYear
Cyclooxygenase-derived vasoconstriction restrains hypoxia-mediated cerebral vasodilation in young adults with metabolic syndrome.
    American journal of physiology. Heart and circulatory physiology, 2014, Jan-15, Volume: 306, Issue:2

    Topics: Adult; Blood Flow Velocity; Carbon Dioxide; Cyclooxygenase Inhibitors; Double-Blind Method; Female;

2014

Other Studies

2 other studies available for indomethacin and Metabolic Syndrome

ArticleYear
Acute administration of single oral dose of grape seed polyphenols restores blood pressure in a rat model of metabolic syndrome: role of nitric oxide and prostacyclin.
    European journal of nutrition, 2016, Volume: 55, Issue:2

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Diet; Dose-Response Relation

2016
Modulation of aortic vascular reactivity by sex hormones in a male rat model of metabolic syndrome.
    Life sciences, 2007, May-16, Volume: 80, Issue:23

    Topics: Animals; Aorta; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Estradiol; Gonadal St

2007