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indomethacin and Mesenteric Vascular Occlusion

indomethacin has been researched along with Mesenteric Vascular Occlusion in 6 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Mesenteric Vascular Occlusion: Obstruction of the flow in the SPLANCHNIC CIRCULATION by ATHEROSCLEROSIS; EMBOLISM; THROMBOSIS; STENOSIS; TRAUMA; and compression or intrinsic pressure from adjacent tumors. Rare causes are drugs, intestinal parasites, and vascular immunoinflammatory diseases such as PERIARTERITIS NODOSA and THROMBOANGIITIS OBLITERANS. (From Juergens et al., Peripheral Vascular Diseases, 5th ed, pp295-6)

Research Excerpts

ExcerptRelevanceReference
"The role of thromboxane and prostacyclin in circulatory shock of intestinal origin was investigated in anesthetized dogs by measuring their stable metabolites, thromboxane B2 (TXB2) and 6-keto-PGF1 alpha, respectively, in superior mesenteric vein (SMV), right ventricle (RV), and aorta during superior mesenteric artery occlusion-induced (SMAO) shock and by inhibiting prostanoid synthesis with indomethacin (IM)."7.67Intestinal and arterial plasma thromboxane and prostacyclin levels in shock: effects of indomethacin. ( Mózes, T; Wieszt, E, 1989)
"The role of thromboxane and prostacyclin in circulatory shock of intestinal origin was investigated in anesthetized dogs by measuring their stable metabolites, thromboxane B2 (TXB2) and 6-keto-PGF1 alpha, respectively, in superior mesenteric vein (SMV), right ventricle (RV), and aorta during superior mesenteric artery occlusion-induced (SMAO) shock and by inhibiting prostanoid synthesis with indomethacin (IM)."3.67Intestinal and arterial plasma thromboxane and prostacyclin levels in shock: effects of indomethacin. ( Mózes, T; Wieszt, E, 1989)
"The role of PGF2 alpha in circulatory shock of intestinal origin was investigated in anesthetized dogs by measuring PGF2 alpha levels in superior mesenteric vein, right ventricle, aorta, and femoral vein during superior mesenteric artery occlusion-induced shock by comparing the circulatory effects of exogenous PGF2 alpha injected into either the superior mesenteric or the femoral vein and by inhibiting of prostanoid synthesis with indomethacin."3.67Role of PGF2 alpha in the superior mesenteric artery-induced shock. ( Mózes, T; Wieszt, E; Zahajszky, T, 1989)
"The role of prostanoids in respiratory failure during circulatory shock of intestinal origin was investigated in anesthetized, non-ventilated dogs by measuring PGF2 alpha thromboxane B2 (TXB2) and 6-keto prostaglandin F1 alpha (PGF1 alpha) in arterial and mixed venous (right ventricle) blood samples during superior mesenteric artery occlusion-induced (SMAO) shock."3.67Role of prostanoids in respiratory failure during circulatory shock of intestinal origin in dogs. ( Mózes, T; Wieszt, E, 1989)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ballabeni, V1
Barocelli, E1
Bertoni, S1
Impicciatore, M1
Krasna, IH1
Kim, H1
Bourgain, RH1
Andries, R1
Braquet, P1
Mózes, T3
Wieszt, E3
Zahajszky, T1

Other Studies

6 other studies available for indomethacin and Mesenteric Vascular Occlusion

ArticleYear
Alterations of intestinal motor responsiveness in a model of mild mesenteric ischemia/reperfusion in rats.
    Life sciences, 2002, Sep-13, Volume: 71, Issue:17

    Topics: Acetylcholine; Animals; Chymotrypsin; Disease Models, Animal; Dose-Response Relationship, Drug; Elec

2002
Indomethacin administration after temporary ischemia causes bowel necrosis in mice.
    Journal of pediatric surgery, 1992, Volume: 27, Issue:7

    Topics: Animals; Enterocolitis, Pseudomembranous; Indomethacin; Intestines; Mesenteric Arteries; Mesenteric

1992
Endotoxin, PAF and arterial thrombosis.
    Journal of lipid mediators, 1990, Volume: 2 Suppl

    Topics: Animals; Endotoxins; Epoprostenol; Guinea Pigs; Indomethacin; Male; Mesenteric Vascular Occlusion; P

1990
Intestinal and arterial plasma thromboxane and prostacyclin levels in shock: effects of indomethacin.
    The Journal of surgical research, 1989, Volume: 47, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Dogs; Epoprostenol; Indomethacin; Male; Mesen

1989
Role of PGF2 alpha in the superior mesenteric artery-induced shock.
    The Journal of surgical research, 1989, Volume: 47, Issue:6

    Topics: Animals; Blood Pressure; Dinoprost; Dogs; Hemodynamics; Indomethacin; Intestinal Mucosa; Intestines;

1989
Role of prostanoids in respiratory failure during circulatory shock of intestinal origin in dogs.
    Prostaglandins, leukotrienes, and essential fatty acids, 1989, Volume: 36, Issue:3

    Topics: Animals; Dogs; Indomethacin; Male; Mesenteric Vascular Occlusion; Prostaglandins; Respiratory Insuff

1989