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indomethacin and Malaria, Falciparum

indomethacin has been researched along with Malaria, Falciparum in 4 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.

Research Excerpts

ExcerptRelevanceReference
"Indomethacin was significantly quicker at clearing fever than acetaminophen (P < 0."2.67Antipyretic efficacy of indomethacin and acetaminophen in uncomplicated falciparum malaria. ( Looareesuwan, S; Wilairatana, P, 1994)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miller, ME1
Parrott, EE1
Singh, R1
Nelson, SW1
Wilairatana, P1
Looareesuwan, S1
Dekker, E1
Romijn, JA1
Ackermans, MT1
Endert, E1
Kager, PA1
Thuy, LT1
Sauerwein, HP1
Alves, MF1
Santos-Neto, LL1
Junqueira, MI1
Tosta, CE1
Costa, CE1

Trials

2 trials available for indomethacin and Malaria, Falciparum

ArticleYear
Antipyretic efficacy of indomethacin and acetaminophen in uncomplicated falciparum malaria.
    Annals of tropical medicine and parasitology, 1994, Volume: 88, Issue:4

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Female; Fever; Humans; Indomethacin; Malaria

1994
Indomethacin stimulates glucose production in adults with uncomplicated falciparum malaria.
    Metabolism: clinical and experimental, 1998, Volume: 47, Issue:2

    Topics: Adult; Cyclooxygenase Inhibitors; Cytokines; Female; Glucose; Humans; Indomethacin; Insulin; Malaria

1998

Other Studies

2 other studies available for indomethacin and Malaria, Falciparum

ArticleYear
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
    Journal of biomolecular screening, 2014, Volume: 19, Issue:6

    Topics: Antimalarials; Apicoplasts; Chloroplasts; DNA; DNA-Directed DNA Polymerase; Drug Discovery; Exonucle

2014
Cytokines and dysregulation of the immune response in human malaria.
    Memorias do Instituto Oswaldo Cruz, 1992, Volume: 87 Suppl 3

    Topics: Dinoprostone; Humans; Indomethacin; Interleukin-1; Leukocytes, Mononuclear; Lymphocyte Activation; M

1992