Page last updated: 2024-10-29

indomethacin and Lymph Node Metastasis

indomethacin has been researched along with Lymph Node Metastasis in 5 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"As a result of preclinical data demonstrating the antitumour and antimetastatic efficiency of indomethacin in murine models, and the clinical observation of occasional tumour regression in patients with advanced melanoma treated with indomethacin together with ranitidine, a Phase II study was performed of prolonged administration of these two oral agents in combination."9.08Oral indomethacin and ranitidine in advanced melanoma: a phase II study. ( Lohmann, RC; Mertens, WC, 1996)
"To investigate the combined effects of indomethacin and oxaliplatin on expressions of epidermal growth factor receptor (EGFR), E-cadherin (E-cad), intercellular adhesion molecule-1 (ICAM-1) and CD44v6 related to lymph node metastasis of human lung cancer cell lines."7.83Combined effects off indomethacin and oxaliplatin on lymph node metastasis related factors in human lung cancerxenografts in nude mice. ( Chen, G; Chen, YQ; Wang, DC; Xing, D; Zhao, YX, 2016)
"As a result of preclinical data demonstrating the antitumour and antimetastatic efficiency of indomethacin in murine models, and the clinical observation of occasional tumour regression in patients with advanced melanoma treated with indomethacin together with ranitidine, a Phase II study was performed of prolonged administration of these two oral agents in combination."5.08Oral indomethacin and ranitidine in advanced melanoma: a phase II study. ( Lohmann, RC; Mertens, WC, 1996)
"To investigate the combined effects of indomethacin and oxaliplatin on expressions of epidermal growth factor receptor (EGFR), E-cadherin (E-cad), intercellular adhesion molecule-1 (ICAM-1) and CD44v6 related to lymph node metastasis of human lung cancer cell lines."3.83Combined effects off indomethacin and oxaliplatin on lymph node metastasis related factors in human lung cancerxenografts in nude mice. ( Chen, G; Chen, YQ; Wang, DC; Xing, D; Zhao, YX, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xing, D1
Chen, YQ1
Wang, DC1
Zhao, YX1
Chen, G1
Metzger, U1
Meier, J1
Uhlschmid, G1
Weihe, H1
Mertens, WC1
Lohmann, RC1
Barrera, JL1
Verastegui, E1
Meneses, A1
Zinser, J1
de la Garza, J1
Hadden, JW1
Ishihara, K1

Trials

2 trials available for indomethacin and Lymph Node Metastasis

ArticleYear
Oral indomethacin and ranitidine in advanced melanoma: a phase II study.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1996, Volume: 8, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antin

1996
Combination immunotherapy of squamous cell carcinoma of the head and neck: a phase 2 trial.
    Archives of otolaryngology--head & neck surgery, 2000, Volume: 126, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamid

2000

Other Studies

3 other studies available for indomethacin and Lymph Node Metastasis

ArticleYear
Combined effects off indomethacin and oxaliplatin on lymph node metastasis related factors in human lung cancerxenografts in nude mice.
    Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:6

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antigens, CD; Antineoplastic Combined C

2016
Influence of various prostaglandin synthesis inhibitors on DMH-induced rat colon cancer.
    Diseases of the colon and rectum, 1984, Volume: 27, Issue:6

    Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Drinking; Eating

1984
[Therapeutic response of interferon-beta in malignant melanoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:4 Pt 1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Female; Humans;

1986