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indomethacin and Lung Injury, Acute

indomethacin has been researched along with Lung Injury, Acute in 4 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"We have reported that airway nociceptors [C fibre receptors (CFRs) and high-threshold Aδ fibre receptors (HTARs)] are activated during oleic acid (OA)-induced acute lung injury."7.77Arachidonic acid products in airway nociceptor activation during acute lung injury. ( Guardiola, J; Li, H; Lin, S; Moldoveanu, B; Xu, L; Yu, J, 2011)
"Acute lung injury was efficiently treated by inhibiting the cascade of inflammation, and reducing the inflammatory response in the lung."5.62Design, synthesis and structure-activity relationship studies of 4-indole-2-arylaminopyrimidine derivatives as anti-inflammatory agents for acute lung injury. ( Chen, T; Wei, Y; Zhang, X; Zhao, H; Zhu, G, 2021)
"We have reported that airway nociceptors [C fibre receptors (CFRs) and high-threshold Aδ fibre receptors (HTARs)] are activated during oleic acid (OA)-induced acute lung injury."3.77Arachidonic acid products in airway nociceptor activation during acute lung injury. ( Guardiola, J; Li, H; Lin, S; Moldoveanu, B; Xu, L; Yu, J, 2011)
"Acute lung injury was efficiently treated by inhibiting the cascade of inflammation, and reducing the inflammatory response in the lung."1.62Design, synthesis and structure-activity relationship studies of 4-indole-2-arylaminopyrimidine derivatives as anti-inflammatory agents for acute lung injury. ( Chen, T; Wei, Y; Zhang, X; Zhao, H; Zhu, G, 2021)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Xia, Q1
Bao, X1
Sun, C1
Wu, D1
Rong, X1
Liu, Z1
Gu, Y1
Zhou, J1
Liang, G1
Chen, T1
Wei, Y1
Zhu, G1
Zhao, H1
Zhang, X1
Kao, RL1
Huang, W1
Martin, CM1
Rui, T1
Lin, S1
Li, H1
Xu, L1
Moldoveanu, B1
Guardiola, J1
Yu, J1

Other Studies

4 other studies available for indomethacin and Lung Injury, Acute

ArticleYear
Design, synthesis and biological evaluation of novel 2-sulfonylindoles as potential anti-inflammatory therapeutic agents for treatment of acute lung injury.
    European journal of medicinal chemistry, 2018, Dec-05, Volume: 160

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dose-Response Relati

2018
Design, synthesis and structure-activity relationship studies of 4-indole-2-arylaminopyrimidine derivatives as anti-inflammatory agents for acute lung injury.
    European journal of medicinal chemistry, 2021, Dec-05, Volume: 225

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cytokines; Dose-Resp

2021
The effect of aerosolized indomethacin on lung inflammation and injury in a rat model of blunt chest trauma
    Canadian journal of surgery. Journal canadien de chirurgie, 2018, 12-01, Volume: 61, Issue:6

    Topics: Acute Lung Injury; Administration, Inhalation; Aerosols; Animals; Anti-Inflammatory Agents, Non-Ster

2018
Arachidonic acid products in airway nociceptor activation during acute lung injury.
    Experimental physiology, 2011, Volume: 96, Issue:9

    Topics: Acute Lung Injury; Animals; Arachidonic Acid; Indomethacin; Ketoconazole; Male; Nociceptors; Oleic A

2011