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indomethacin and Lung Diseases, Obstructive

indomethacin has been researched along with Lung Diseases, Obstructive in 12 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Lung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.

Research Excerpts

ExcerptRelevanceReference
"A recent study showed that indomethacin reduces the perception of dyspnea during submaximal exercise in normal subjects (1)."9.06Indomethacin and perception of dyspnea in chronic airflow obstruction. ( Brown, SE; Fischer, CE; Light, RW; Sato, RI; Schiffman, GL; Stansbury, DW, 1988)
"A recent study showed that indomethacin reduces the perception of dyspnea during submaximal exercise in normal subjects (1)."5.06Indomethacin and perception of dyspnea in chronic airflow obstruction. ( Brown, SE; Fischer, CE; Light, RW; Sato, RI; Schiffman, GL; Stansbury, DW, 1988)
" Because Indo may interfere with the hypotensive effect of hydralazine and because hydralazine has been proposed in the treatment of patients with pulmonary hypertension, 7 of these patients also received 0."3.67Effects of indomethacin on pulmonary hemodynamics and gas exchange in patients with pulmonary artery hypertension, interference with hydralazine. ( Adnot, S; Brun-Buisson, C; de Cremoux, H; Defouilloy, C; Lemaire, F; Piquet, J, 1987)
"When indomethacin was added simultaneously with IL-2, the proliferative response for 12 of 19 patients was increased significantly more than for the normal controls."1.27The effects of indomethacin and interleukin-2 on the proliferation of lymphocytes from patients with lung cancer. ( Burford, JG; Maca, RD; Taylor, RT, 1985)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's3 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Seale, JP1
Pillay, SP1
Hardie, IR1
Burnett, W1
Wang, ZW1
Yu, MF1
Robinson, NE1
Derksen, FJ1
Fitting, JW1
Vigdahl, RL1
Ferber, RH1
Parrish, SL1
Weir, EK1
McMurtry, IF1
Tucker, A1
Reeves, JT1
Grover, RF1
Dinh-Xuan, AT1
Higenbottam, TW1
Wallwork, J1
Schiffman, GL1
Stansbury, DW1
Fischer, CE1
Sato, RI1
Light, RW1
Brown, SE1
Adnot, S1
Defouilloy, C1
Brun-Buisson, C1
Piquet, J1
de Cremoux, H1
Lemaire, F1
Maca, RD1
Burford, JG1
Taylor, RT1
Fairshter, RD1
Weinberg, MS1
Quigg, RJ1
Salant, DJ1
Bernard, DB1

Reviews

2 reviews available for indomethacin and Lung Diseases, Obstructive

ArticleYear
Prostaglandins, slow-reacting substances (leukotrienes) and the lung.
    Australian and New Zealand journal of medicine, 1981, Volume: 11, Issue:5

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Bronchi; Epoprostenol; Guinea Pigs; H

1981
[Symptomatic pharmacological treatment of dyspnea].
    Revue des maladies respiratoires, 1993, Volume: 10, Issue:2

    Topics: Anesthetics, Local; Benzodiazepines; Dyspnea; Humans; Indomethacin; Lung Diseases, Obstructive; Narc

1993

Trials

1 trial available for indomethacin and Lung Diseases, Obstructive

ArticleYear
Indomethacin and perception of dyspnea in chronic airflow obstruction.
    The American review of respiratory disease, 1988, Volume: 137, Issue:5

    Topics: Double-Blind Method; Dyspnea; Forced Expiratory Volume; Humans; Indomethacin; Lung Diseases, Obstruc

1988

Other Studies

9 other studies available for indomethacin and Lung Diseases, Obstructive

ArticleYear
Emergency surgery for the complications of peptic ulcer in the elderly.
    The Australian and New Zealand journal of surgery, 1981, Volume: 51, Issue:6

    Topics: Aged; Emergencies; Heart Failure; Humans; Indomethacin; Lung Diseases, Obstructive; Peptic Ulcer; Sa

1981
Acetylcholine release from airway cholinergic nerves in horses with heaves, an airway obstructive disease.
    American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:3 Pt 1

    Topics: Acetylcholine; Animals; Atropine; Bronchi; Cholinergic Fibers; Chromatography, High Pressure Liquid;

1995
Evaluation of antiinflammatory and antithrombotic drugs in pulmonary and arterial thrombosis.
    Thrombosis research, 1979, Volume: 16, Issue:1-2

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Anti-Inflammatory Agents; Arterial Occlusive Di

1979
Prostaglandin synthetase inhibitors do not decrease hypoxic pulmonary vasoconstriction.
    Journal of applied physiology, 1976, Volume: 41, Issue:5 Pt. 1

    Topics: Animals; Cattle; Cyclooxygenase Inhibitors; Dogs; Female; Hypoxia; Indomethacin; Lung Diseases, Obst

1976
Relationship between chronic hypoxia and in vitro pulmonary relaxation mediated by endothelium-derived relaxing factors in human chronic obstructive lung disease.
    Angiology, 1992, Volume: 43, Issue:4

    Topics: Acetylcholine; Chronic Disease; Endothelium, Vascular; Humans; Hypoxia; In Vitro Techniques; Indomet

1992
Effects of indomethacin on pulmonary hemodynamics and gas exchange in patients with pulmonary artery hypertension, interference with hydralazine.
    The American review of respiratory disease, 1987, Volume: 136, Issue:6

    Topics: Aged; Cardiac Catheterization; Drug Evaluation; Drug Interactions; Female; Hemodynamics; Humans; Hyd

1987
The effects of indomethacin and interleukin-2 on the proliferation of lymphocytes from patients with lung cancer.
    Journal of clinical immunology, 1985, Volume: 5, Issue:3

    Topics: Cells, Cultured; Dinoprostone; DNA Replication; Humans; Indomethacin; Interleukin-2; Lung Diseases,

1985
Airway hysteresis in normal subjects and individuals with chronic airflow obstruction.
    Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:5

    Topics: Adult; Airway Resistance; Ascorbic Acid; Aspirin; Bronchi; Female; Humans; Indomethacin; Lung Compli

1985
Anuric renal failure precipitated by indomethacin and triamterene.
    Nephron, 1985, Volume: 40, Issue:2

    Topics: Acute Kidney Injury; Aged; Angina Pectoris; Anuria; Drug Interactions; Female; Humans; Indomethacin;

1985