indomethacin has been researched along with Liver Neoplasms in 39 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As a result of preclinical data demonstrating the antitumour and antimetastatic efficiency of indomethacin in murine models, and the clinical observation of occasional tumour regression in patients with advanced melanoma treated with indomethacin together with ranitidine, a Phase II study was performed of prolonged administration of these two oral agents in combination." | 9.08 | Oral indomethacin and ranitidine in advanced melanoma: a phase II study. ( Lohmann, RC; Mertens, WC, 1996) |
| " Therefore, we aimed to evaluate novel indomethacin derivatives for the treatment of hepatocellular carcinoma." | 8.02 | Functional Role of Novel Indomethacin Derivatives for the Treatment of Hepatocellular Carcinoma Through Inhibition of Platelet-Derived Growth Factor. ( Chavda, V; Nanavati, P; Patel, S; Savjani, J; Sharma, J, 2021) |
| " The authors report a patient with hepatocellular carcinoma associated with diarrhea mediated by prostaglandins, surviving 30 months after receiving treatment with indomethacin and Adriamycin." | 7.67 | Long survival of diarrhea-associated hepatocarcinoma treated with Adriamycin and indomethacin. A case report. ( Barcena, R; Boixeda, D; Moreno, A; Saban, J; Serrano-Rios, M, 1986) |
| "Twenty-one patients with advanced hepatocellular carcinoma were randomly divided into two groups." | 6.69 | [Effect of indomethacin on natural killer(NK) cell and T lymphocyte subsets from patients with hepatocellular carcinoma]. ( Chen, FY; Yuan, WJ; Zhang, GY, 2000) |
| "Indomethacin pretreatment is used as a potential chemopreventive agent in cancers for it could assist in anti-tumor functions of other agents and exert anti-tumor effect." | 5.42 | Long-term use of indomethacin leads to poor prognoses through promoting the expression of PD-1 and PD-L2 via TRIF/NF-κB pathway and JAK/STAT3 pathway to inhibit TNF-α and IFN-γ in hepatocellular carcinoma. ( Miao, C; Sun, Z; Wang, Y; Xu, P, 2015) |
| "Pretreatment with tocopheryl nicotinate and indomethacin increased the K values in the control subjects, but was without effect on the K values in patients with primary hepatoma." | 5.26 | Decreased disappearance rate of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) from the blood and its unresponsiveness to tocophreyl nicotinate and indomethacin in patients with primary hepatocellular carcinoma. ( Hobara, N; Watanabe, A, 1979) |
| "As a result of preclinical data demonstrating the antitumour and antimetastatic efficiency of indomethacin in murine models, and the clinical observation of occasional tumour regression in patients with advanced melanoma treated with indomethacin together with ranitidine, a Phase II study was performed of prolonged administration of these two oral agents in combination." | 5.08 | Oral indomethacin and ranitidine in advanced melanoma: a phase II study. ( Lohmann, RC; Mertens, WC, 1996) |
| " Therefore, we aimed to evaluate novel indomethacin derivatives for the treatment of hepatocellular carcinoma." | 4.02 | Functional Role of Novel Indomethacin Derivatives for the Treatment of Hepatocellular Carcinoma Through Inhibition of Platelet-Derived Growth Factor. ( Chavda, V; Nanavati, P; Patel, S; Savjani, J; Sharma, J, 2021) |
| "We investigated the antitumor effects of a synthetic lipid A derivative, DT-5461a, in combination with indomethacin in three experimental tumor models (peritoneal carcinomatosis, liver tumor, and lung tumor models) of transplanted colon 26 carcinoma in mice." | 3.69 | Effect of combined administration of a synthetic low-toxicity lipid A derivative, DT-5461a, and indomethacin in various experimental tumor models of colon 26 carcinoma in mice. ( Akimoto, T; Jimbo, T; Tohgo, A, 1995) |
| "The PGE2 concentration of sera and tumor tissues in human hepatocellular carcinoma (hHCC) xenografts in nude mice was examined by radio-immuno-assay (RIA) and the effect of intraperitoneal administration of exogenous of PGE2 as well as indomethacin on tumor growth was studied." | 3.68 | [In vivo studies on PGE2 production by human hepatocellular carcinoma xenografts in nude mice]. ( Shi, LH, 1993) |
| "In order to investigate the production of PGE2 and its' function in human hepatocellular carcinoma, the effects of indomethacin and PGE2 on tumor growth were examined using in vivo and in vitro techniques." | 3.67 | [In vivo and in vitro studies on PGE2 production and function in human hepatocellular carcinoma]. ( Itakura, M; Nakase, A; Nohara, T, 1989) |
| " The authors report a patient with hepatocellular carcinoma associated with diarrhea mediated by prostaglandins, surviving 30 months after receiving treatment with indomethacin and Adriamycin." | 3.67 | Long survival of diarrhea-associated hepatocarcinoma treated with Adriamycin and indomethacin. A case report. ( Barcena, R; Boixeda, D; Moreno, A; Saban, J; Serrano-Rios, M, 1986) |
| "Twenty-one patients with advanced hepatocellular carcinoma were randomly divided into two groups." | 2.69 | [Effect of indomethacin on natural killer(NK) cell and T lymphocyte subsets from patients with hepatocellular carcinoma]. ( Chen, FY; Yuan, WJ; Zhang, GY, 2000) |
| "Indomethacin pretreatment is used as a potential chemopreventive agent in cancers for it could assist in anti-tumor functions of other agents and exert anti-tumor effect." | 1.42 | Long-term use of indomethacin leads to poor prognoses through promoting the expression of PD-1 and PD-L2 via TRIF/NF-κB pathway and JAK/STAT3 pathway to inhibit TNF-α and IFN-γ in hepatocellular carcinoma. ( Miao, C; Sun, Z; Wang, Y; Xu, P, 2015) |
| "Indomethacin prodrugs were synthesized and characterized by FTIR and NMR, and dissolution test simulating gastrointestinal tract was employed to screen the colon-specific prodrug." | 1.36 | [Synthesis of colon-specific prodrug of indomethacin and its inhibitory effect on liver metastasis from colon cancer]. ( Cai, X; Chen, RF; Jiang, ZP; Li, LQ; Li, ZH; Peng, NF; Yang, LQ; Zhou, JJ; Zhou, QB, 2010) |
| "By an autopsy, hepatocellular carcinoma was found in the right lobe of the liver." | 1.27 | Prostaglandin-E-producing hepatocellular carcinoma with hypercalcemia. ( Hasumura, Y; Ikeda, T; Takeuchi, J; Tozuka, S, 1988) |
| "Fever of unknown origin was experienced by 45 patients of Group A (31%) and 39 of Group B (26." | 1.27 | Absence of correlation between liver metastases and unexplained fever episodes. ( Aderka, D; Kidron, D; Pinkhas, J; Weinberger, A, 1985) |
| "Pretreatment with tocopheryl nicotinate and indomethacin increased the K values in the control subjects, but was without effect on the K values in patients with primary hepatoma." | 1.26 | Decreased disappearance rate of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) from the blood and its unresponsiveness to tocophreyl nicotinate and indomethacin in patients with primary hepatocellular carcinoma. ( Hobara, N; Watanabe, A, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (51.28) | 18.7374 |
| 1990's | 7 (17.95) | 18.2507 |
| 2000's | 6 (15.38) | 29.6817 |
| 2010's | 5 (12.82) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 2 |
| Liu, L | 1 |
| Zheng, C | 1 |
| Wang, Y | 2 |
| Nie, X | 1 |
| Shi, D | 1 |
| Chen, Y | 1 |
| Wei, G | 1 |
| Wang, J | 1 |
| Peng, X | 1 |
| Gao, J | 1 |
| Yuan, Y | 1 |
| Liu, H | 1 |
| Lei, W | 1 |
| Li, S | 1 |
| Zhang, J | 1 |
| Wang, S | 1 |
| Patel, S | 1 |
| Nanavati, P | 1 |
| Sharma, J | 1 |
| Chavda, V | 1 |
| Savjani, J | 1 |
| Xu, P | 1 |
| Sun, Z | 1 |
| Miao, C | 1 |
| Peng, NF | 1 |
| Yang, LQ | 1 |
| Chen, RF | 1 |
| Cai, X | 1 |
| Li, LQ | 1 |
| Li, ZH | 1 |
| Zhou, QB | 1 |
| Zhou, JJ | 1 |
| Jiang, ZP | 1 |
| Ye, CG | 1 |
| Wu, WK | 1 |
| Yeung, JH | 1 |
| Li, HT | 1 |
| Li, ZJ | 1 |
| Wong, CC | 1 |
| Ren, SX | 1 |
| Fung, KP | 1 |
| Cho, CH | 1 |
| Yuan, WJ | 1 |
| Chen, FY | 1 |
| Zhang, GY | 1 |
| Tabernero, A | 1 |
| Schneider, F | 1 |
| Potenza, MA | 1 |
| Randriamboavonjy, V | 1 |
| Chasserot, S | 1 |
| Wolf, P | 1 |
| Mitolo-Chieppa, D | 1 |
| Stoclet, JC | 1 |
| Andriantsitohaina, R | 1 |
| Horani, MH | 1 |
| Gobal, F | 1 |
| Haas, MJ | 1 |
| Wong, NC | 1 |
| Mooradian, AD | 1 |
| Park, WH | 1 |
| Joo, ST | 1 |
| Park, KK | 1 |
| Chang, YC | 1 |
| Kim, CH | 1 |
| Romeu, J | 1 |
| Chadha, N | 1 |
| Fukilman, O | 1 |
| Dave, P | 1 |
| Lee, M | 1 |
| Mahmud, I | 1 |
| Miura, Y | 1 |
| Fennelly, JJ | 1 |
| Cantwell, B | 1 |
| Fielding, JF | 1 |
| FitzGerald, O | 1 |
| Collins, PG | 1 |
| Buchanan, KD | 1 |
| Metzger, U | 1 |
| Meier, J | 1 |
| Uhlschmid, G | 1 |
| Weihe, H | 1 |
| Bredt, AB | 1 |
| Girey, GJ | 1 |
| Warshaw, AL | 1 |
| Carey, RW | 1 |
| Robinson, DR | 1 |
| Jimbo, T | 1 |
| Akimoto, T | 1 |
| Tohgo, A | 1 |
| Kasckow, JW | 1 |
| Mulcahey, JJ | 1 |
| Han, JH | 1 |
| Owens, MJ | 1 |
| Stipetic, MD | 1 |
| Breitman, D | 1 |
| Nemeroff, CB | 1 |
| Shi, LH | 1 |
| Mertens, WC | 1 |
| Lohmann, RC | 1 |
| Sekhar, KR | 1 |
| Spitz, DR | 1 |
| Harris, S | 1 |
| Nguyen, TT | 1 |
| Meredith, MJ | 1 |
| Holt, JT | 1 |
| Gius, D | 1 |
| Marnett, LJ | 1 |
| Summar, ML | 1 |
| Freeman, ML | 1 |
| Guis, D | 1 |
| Marinho, R | 1 |
| Pinto, R | 1 |
| Santos, ML | 1 |
| de, M | 1 |
| Benvenisti, D | 1 |
| Goldberg, H | 1 |
| Hobara, N | 1 |
| Watanabe, A | 1 |
| Robertson, RP | 1 |
| Baylink, DJ | 1 |
| Marini, BJ | 1 |
| Adkison, HW | 1 |
| Liu, LM | 1 |
| Yu, EX | 1 |
| Tzanakakis, GN | 1 |
| Agarwal, KC | 1 |
| Veronikis, DK | 1 |
| Vezeridis, MP | 1 |
| Hietanen, E | 1 |
| Bartsch, H | 1 |
| Bereziat, JC | 1 |
| Ahotupa, M | 1 |
| Camus, AM | 1 |
| Cabral, JR | 1 |
| Laitinen, M | 1 |
| Itakura, M | 1 |
| Nohara, T | 1 |
| Nakase, A | 1 |
| Gupta, C | 1 |
| Banks, M | 1 |
| Shinozuka, H | 1 |
| Ikeda, T | 1 |
| Tozuka, S | 1 |
| Hasumura, Y | 1 |
| Takeuchi, J | 1 |
| Abe, S | 1 |
| Saban, J | 1 |
| Boixeda, D | 1 |
| Moreno, A | 1 |
| Barcena, R | 1 |
| Serrano-Rios, M | 1 |
| Yokota, M | 1 |
| Sakamoto, S | 1 |
| Koga, S | 1 |
| Ibayashi, H | 1 |
| Aderka, D | 1 |
| Kidron, D | 1 |
| Weinberger, A | 1 |
| Pinkhas, J | 1 |
| Hilario, E | 1 |
| Unda, F | 1 |
| Aliño, SF | 1 |
| Ellison, NM | 1 |
| Servi, RJ | 1 |
| Apps, MC | 1 |
| Cater, DB | 1 |
| Delaveirre, PH | 1 |
| Hureau, J | 1 |
| Grivaux, M | 1 |
| Chretien, J | 1 |
| Etienne, JP | 1 |
2 trials available for indomethacin and Liver Neoplasms
| Article | Year |
|---|---|
[Effect of indomethacin on natural killer(NK) cell and T lymphocyte subsets from patients with hepatocellular carcinoma].
Topics: Adjuvants, Immunologic; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Fem | 2000 |
Oral indomethacin and ranitidine in advanced melanoma: a phase II study.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antin | 1996 |
37 other studies available for indomethacin and Liver Neoplasms
| Article | Year |
|---|---|
Synthesis and biological evaluation of novel podophyllotoxin-NSAIDs conjugates as multifunctional anti-MDR agents against resistant human hepatocellular carcinoma Bel-7402/5-FU cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line | 2017 |
Hypoxia-Activated and Indomethacin-Mediated Theranostic Prodrug Releasing Drug On-Demand for Tumor Imaging and Therapy.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; | 2019 |
Functional Role of Novel Indomethacin Derivatives for the Treatment of Hepatocellular Carcinoma Through Inhibition of Platelet-Derived Growth Factor.
Topics: Carcinoma, Hepatocellular; Humans; Indomethacin; Liver Neoplasms; Molecular Docking Simulation; Plat | 2021 |
Long-term use of indomethacin leads to poor prognoses through promoting the expression of PD-1 and PD-L2 via TRIF/NF-κB pathway and JAK/STAT3 pathway to inhibit TNF-α and IFN-γ in hepatocellular carcinoma.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, | 2015 |
[Synthesis of colon-specific prodrug of indomethacin and its inhibitory effect on liver metastasis from colon cancer].
Topics: Amylose; Animals; Colon; Colonic Neoplasms; Delayed-Action Preparations; Drug Delivery Systems; HT29 | 2010 |
Indomethacin and SC236 enhance the cytotoxicity of doxorubicin in human hepatocellular carcinoma cells via inhibiting P-glycoprotein and MRP1 expression.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Tr | 2011 |
Cyclooxygenase-2 and inducible nitric oxide synthase in omental arteries harvested from patients with severe liver diseases: immuno-localization and influence on vascular tone.
Topics: Adult; Arteries; Blotting, Western; Carcinoma, Hepatocellular; Case-Control Studies; Cyclooxygenase | 2003 |
Cyclooxygenase inhibition is associated with downregulation of apolipoprotein AI promoter activity in cultured hepatoma cell line HepG2.
Topics: Apolipoprotein A-I; Arachidonic Acid; Aspirin; Blotting, Northern; Blotting, Western; Carcinoma, Hep | 2004 |
Effects of the Geiji-Bokryung-Hwan on carrageenan-induced inflammation in mice and cyclooxygenase-2 in hepatoma cells of HepG2 and Hep3B.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Hepat | 2004 |
Indomethacin therapy in symptomatic hepatic neoplasms.
Topics: Adenocarcinoma; Aged; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Female; Humans; Indometha | 1982 |
Effects of stimulators and inhibitors on arachidonic acid metabolism in hepatoma.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Butylated Hydroxytoluene; Carcinoma, Hepatoce | 1981 |
Metastatic pancreatic vipoma: a case report of clinical response following treatment with corticosteroids and actinomycin D.
Topics: Adenoma, Islet Cell; Dactinomycin; Female; Humans; Indomethacin; Liver Neoplasms; Middle Aged; Pancr | 1982 |
Influence of various prostaglandin synthesis inhibitors on DMH-induced rat colon cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Drinking; Eating | 1984 |
Antipyretic effects of indomethacin in liver metastases of solid tumors.
Topics: Drug Administration Schedule; Female; Fever; Humans; Indomethacin; Liver Neoplasms; Male; Middle Age | 1982 |
Control of fever associated with visceral cancers by indomethacin.
Topics: Abdominal Neoplasms; Adenocarcinoma; Adult; Aged; Female; Fever; Humans; Indomethacin; Liver Neoplas | 1981 |
Effect of combined administration of a synthetic low-toxicity lipid A derivative, DT-5461a, and indomethacin in various experimental tumor models of colon 26 carcinoma in mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dinoprostone; Disacchari | 1995 |
Interleukin-1 alpha induces corticotropin-releasing factor secretion and synthesis from NPLC-KC cells through various second messenger pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoma, Hepatocellular; Corticotropin-Releasing Ho | 1994 |
[In vivo studies on PGE2 production by human hepatocellular carcinoma xenografts in nude mice].
Topics: Animals; Carcinoma, Hepatocellular; Dinoprostone; Humans; Indomethacin; Injections, Intraperitoneal; | 1993 |
Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Carcinoma, Hepatocellular; Carrier Prot | 2002 |
Evidence for prostaglandin-producing supressor cells in HCV patients with normal ALT.
Topics: Alanine Transaminase; Carcinoma, Hepatocellular; Carrier State; Dinoprostone; Hepatitis C Antigens; | 2002 |
Letter: Prostaglandins, indomethacin and hypercalcemia in neoplastic disease.
Topics: Aged; Carcinoma, Squamous Cell; Humans; Hypercalcemia; Indomethacin; Liver Neoplasms; Lung Neoplasms | 1975 |
Decreased disappearance rate of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) from the blood and its unresponsiveness to tocophreyl nicotinate and indomethacin in patients with primary hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Fluorouracil; Humans; Indomethacin; Kinetics; Liver Cirrhosis; Liver Neop | 1979 |
Elevated prostaglandins and suppressed parathyroid hormone associated with hypercalcemia and renal cell carcinoma.
Topics: Adenocarcinoma; Calcium; Humans; Hypercalcemia; Indomethacin; Kidney Cortex; Liver; Liver Neoplasms; | 1975 |
[Comprehensive "4-step analgesic ladder" therapy in treating cancer-related pain-analysis of 486 cases].
Topics: Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Drugs, Chinese Herbal; Female; Humans; Indomethac | 1992 |
Effects of antiplatelet agents alone or in combinations on platelet aggregation and on liver metastases from a human pancreatic adenocarcinoma in the nude mouse.
Topics: Adenocarcinoma; Animals; Colforsin; Drug Interactions; Humans; Indomethacin; Ketoconazole; Liver Neo | 1991 |
Quantity and saturation degree of dietary fats as modulators of oxidative stress and chemically-induced liver tumours in rats.
Topics: Animals; Biomarkers; Blood Chemical Analysis; Cell Transformation, Neoplastic; Cholesterol; Dietary | 1990 |
[In vivo and in vitro studies on PGE2 production and function in human hepatocellular carcinoma].
Topics: Animals; Carcinoma, Hepatocellular; Dinoprostone; Humans; Indomethacin; Liver Neoplasms; Male; Mice; | 1989 |
Elevated levels of prostaglandin E2 in the liver of rats fed a choline deficient diet: possible involvement in liver tumor promotion.
Topics: Animals; Choline Deficiency; Diethylhexyl Phthalate; Dinoprostone; Fish Oils; gamma-Glutamyltransfer | 1989 |
Prostaglandin-E-producing hepatocellular carcinoma with hypercalcemia.
Topics: Aged; Carcinoma, Hepatocellular; Humans; Hypercalcemia; Indomethacin; Liver Neoplasms; Male; Phospha | 1988 |
Effects of arachidonic acid and indomethacin on sister-chromatid exchange induction by polycyclic aromatic hydrocarbons in mammalian cell lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonic Acid; Arachidonic Acids; Aryl Hydrocarbon Hyd | 1986 |
Long survival of diarrhea-associated hepatocarcinoma treated with Adriamycin and indomethacin. A case report.
Topics: Adult; Carcinoma, Hepatocellular; Diarrhea; Doxorubicin; Drug Therapy, Combination; Humans; Indometh | 1986 |
Decreased interleukin 1 activity in culture supernatant of lipopolysaccharide stimulated monocytes from patients with liver cirrhosis and hepatocellular carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Body Temperature; C-Reactive Protein; Carcinoma, Hepatocellular; Din | 1987 |
Absence of correlation between liver metastases and unexplained fever episodes.
Topics: Adrenal Cortex Hormones; Aged; Breast Neoplasms; Diagnostic Errors; Digestive System Neoplasms; Fema | 1985 |
Differential distribution of B16F10 melanoma cells in the liver lobule.
Topics: Animals; Cell Line; Female; Indomethacin; Liver Neoplasms; Male; Melanoma; Mice; Mice, Inbred Strain | 1988 |
Acute renal failure and death following sequential intermediate-dose methotrexate and 5-FU: a possible adverse effect due to concomitant indomethacin administration.
Topics: Acute Kidney Injury; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic N | 1985 |
Production of histamine-like and prostaglandin-like substances from serum incubated with rat, dog, mouse or human tumours.
Topics: Acetates; Animals; Aspirin; Carcinoma, Hepatocellular; Complement System Proteins; Dogs; Histamine; | 1973 |
[Iatrogenic gastroduodenal ulcerations. Corticosteroids excluded].
Topics: Aged; Bone Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Duodenal Ulcer; Female; Humans; In | 1973 |