indomethacin has been researched along with Liver Failure in 4 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study reports the effect of indomethacin on four occasions of intracranial hypertension, in a 23-year old previously healthy woman with severe acetaminophen poisoning." | 7.69 | Indomethacin normalizes intracranial pressure in acute liver failure: a twenty-three-year-old woman treated with indomethacin. ( Clemmesen, JO; Hansen, BA; Larsen, FS, 1997) |
| "Indomethacin treatment led to distortion of hepatic cell arrangement as well as marked cellular infiltration and congestion." | 5.29 | Studies on the effect of acute doses of indomethacin (prostaglandins inhibitor) during induced liver failure. ( Abdel-Wahab, MM; Bayoumy, AS; Hassounah, OA, 1995) |
| " The present study reports the effect of indomethacin on four occasions of intracranial hypertension, in a 23-year old previously healthy woman with severe acetaminophen poisoning." | 3.69 | Indomethacin normalizes intracranial pressure in acute liver failure: a twenty-three-year-old woman treated with indomethacin. ( Clemmesen, JO; Hansen, BA; Larsen, FS, 1997) |
| "Indomethacin treatment led to distortion of hepatic cell arrangement as well as marked cellular infiltration and congestion." | 1.29 | Studies on the effect of acute doses of indomethacin (prostaglandins inhibitor) during induced liver failure. ( Abdel-Wahab, MM; Bayoumy, AS; Hassounah, OA, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tabernero, A | 1 |
| Schneider, F | 1 |
| Potenza, MA | 1 |
| Randriamboavonjy, V | 1 |
| Chasserot, S | 1 |
| Wolf, P | 1 |
| Mitolo-Chieppa, D | 1 |
| Stoclet, JC | 1 |
| Andriantsitohaina, R | 1 |
| Tofteng, F | 1 |
| Larsen, FS | 2 |
| Hassounah, OA | 1 |
| Bayoumy, AS | 1 |
| Abdel-Wahab, MM | 1 |
| Clemmesen, JO | 1 |
| Hansen, BA | 1 |
4 other studies available for indomethacin and Liver Failure
| Article | Year |
|---|---|
Cyclooxygenase-2 and inducible nitric oxide synthase in omental arteries harvested from patients with severe liver diseases: immuno-localization and influence on vascular tone.
Topics: Adult; Arteries; Blotting, Western; Carcinoma, Hepatocellular; Case-Control Studies; Cyclooxygenase | 2003 |
The effect of indomethacin on intracranial pressure, cerebral perfusion and extracellular lactate and glutamate concentrations in patients with fulminant hepatic failure.
Topics: Adult; Blood Pressure; Brain; Brain Chemistry; Extracellular Space; Female; Glutamic Acid; Homeostas | 2004 |
Studies on the effect of acute doses of indomethacin (prostaglandins inhibitor) during induced liver failure.
Topics: Animals; Carbon Tetrachloride Poisoning; Dose-Response Relationship, Drug; Indomethacin; Kidney Func | 1995 |
Indomethacin normalizes intracranial pressure in acute liver failure: a twenty-three-year-old woman treated with indomethacin.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Arteries; Fatal Outcome; Fem | 1997 |