indomethacin has been researched along with Leukocytosis in 9 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Leukocytosis: A transient increase in the number of leukocytes in a body fluid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Despite the reduction in leukocytosis, implantation was prevented by the high dose of indomethacin." | 5.27 | Suppression of leukocytosis by the intrauterine delivery of high doses of indomethacin in the rat. ( Hurst, PR; Peplow, PV, 1985) |
| "Other known leukocytosis factors, such as epinephrine, dexamethasone, lipopolysaccharide, and the prostanoid 15(S)-15-methyl PGF2 alpha, produced a distinctly different profile of leukocyte mobilization than that of C5a." | 1.28 | C5a-induced neutrophilia. A primary humoral mechanism for recruitment of neutrophils. ( Hugli, TE; Kajita, T, 1990) |
| "Despite the reduction in leukocytosis, implantation was prevented by the high dose of indomethacin." | 1.27 | Suppression of leukocytosis by the intrauterine delivery of high doses of indomethacin in the rat. ( Hurst, PR; Peplow, PV, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greer, KE | 1 |
| Cooper, PH | 1 |
| Sandberg, G | 1 |
| Bezerra, MM | 1 |
| de Lima, V | 1 |
| Alencar, VB | 1 |
| Vieira, IB | 1 |
| Brito, GA | 1 |
| Ribeiro, RA | 1 |
| Rocha, FA | 1 |
| Kajita, T | 1 |
| Hugli, TE | 1 |
| Tuomanen, E | 1 |
| Hengstler, B | 1 |
| Rich, R | 1 |
| Bray, MA | 1 |
| Zak, O | 1 |
| Tomasz, A | 1 |
| Sato, K | 2 |
| Mimura, H | 1 |
| Han, DC | 1 |
| Kakiuchi, T | 1 |
| Ueyama, Y | 1 |
| Ohkawa, H | 1 |
| Okabe, T | 1 |
| Kondo, Y | 1 |
| Ohsawa, N | 1 |
| Tsushima, T | 1 |
| Fujii, Y | 1 |
| Ono, M | 1 |
| Nomura, H | 1 |
| Shizume, K | 1 |
| Hurst, PR | 1 |
| Peplow, PV | 1 |
| Julou, L | 1 |
| Ducrot, R | 1 |
| Fournel, J | 1 |
| Ganter, P | 1 |
| Populaire, P | 1 |
| Durel, J | 1 |
| Myon, J | 1 |
| Pascal, S | 1 |
| Pasquet, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of Immunoregulatory Factor Expression and Immune Responses in Patients With Squamous Cell Carcinoma or Papilloma of the Upper Aerodigestive Tract[NCT00001603] | 93 participants | Observational | 1996-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for indomethacin and Leukocytosis
| Article | Year |
|---|---|
Sweet's syndrome (acute febrile neutrophilic dermatosis).
Topics: Adult; Arthritis; Clofazimine; Diagnosis, Differential; Eye Diseases; Female; Fever; Humans; Indomet | 1982 |
8 other studies available for indomethacin and Leukocytosis
| Article | Year |
|---|---|
Leukocyte mobilization from the guinea pig spleen by muscarinic cholinergic stimulation.
Topics: Animals; Atropine; Carbachol; Cell Movement; Granulocytes; Guinea Pigs; Hematopoiesis, Extramedullar | 1994 |
Selective cyclooxygenase-2 inhibition prevents alveolar bone loss in experimental periodontitis in rats.
Topics: Alveolar Bone Loss; Alveolar Process; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; | 2000 |
C5a-induced neutrophilia. A primary humoral mechanism for recruitment of neutrophils.
Topics: Animals; Cell Division; Complement C5a; Dexamethasone; Dinoprost; Epinephrine; Humans; Indomethacin; | 1990 |
Nonsteroidal anti-inflammatory agents in the therapy for experimental pneumococcal meningitis.
Topics: Ampicillin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacteriolysis; Cell Wall; Cerebrospina | 1987 |
Production of bone-resorbing activity and colony-stimulating activity in vivo and in vitro by a human squamous cell carcinoma associated with hypercalcemia and leukocytosis.
Topics: Animals; Bone Resorption; Carcinoma, Squamous Cell; Chromatography, Gel; Colony-Stimulating Factors; | 1986 |
Production of interleukin 1 alpha-like factor and colony-stimulating factor by a squamous cell carcinoma of the thyroid (T3M-5) derived from a patient with hypercalcemia and leukocytosis.
Topics: Aged; Bone Resorption; Carcinoma, Squamous Cell; Chromatography, Ion Exchange; Colony-Stimulating Fa | 1987 |
Suppression of leukocytosis by the intrauterine delivery of high doses of indomethacin in the rat.
Topics: Animals; Anti-Inflammatory Agents; Biological Availability; Drug Implants; Female; Indomethacin; Leu | 1985 |
[Toxicologic study of methiazinic acid (16091 R.P)].
Topics: Abnormalities, Drug-Induced; Acetates; Anemia; Animals; Dogs; Drug Tolerance; Female; Gastric Mucosa | 1969 |