indomethacin has been researched along with Leishmaniasis, Visceral in 6 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Leishmaniasis, Visceral: A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Visceral leishmaniasis is associated with an antigen-specific immunosuppression during the acute disease." | 1.28 | Antigen-specific immunosuppression in visceral leishmaniasis is cell mediated. ( Bacellar, O; Badaro, R; Barral, A; Carvalho, EM; Johnson, WD, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kirkpatrick, CE | 1 |
| Farrell, JP | 1 |
| Saha, B | 2 |
| Bandyopadhyay, D | 1 |
| Roy, S | 1 |
| Das, G | 1 |
| Vohra, H | 1 |
| Ganguly, NK | 1 |
| Mishra, GC | 1 |
| Carvalho, EM | 1 |
| Bacellar, O | 1 |
| Barral, A | 1 |
| Badaro, R | 1 |
| Johnson, WD | 1 |
| Murray, HW | 1 |
| Carriero, SM | 1 |
| Donelly, DM | 1 |
| Treske, U | 1 |
6 other studies available for indomethacin and Leishmaniasis, Visceral
| Article | Year |
|---|---|
Mechanisms of depression of splenic natural killer cell function in C57BL/6 mice infected with Leishmania donovani.
Topics: Animals; Cytotoxicity, Immunologic; Female; Immunity, Cellular; Immunity, Innate; Indomethacin; Inte | 1984 |
Immunobiological studies on experimental visceral leishmaniasis. IV. Kinetics of evolution of disease-promoting versus host-protective cells of monocyte-macrophage lineage and their characterization.
Topics: Animals; Antigen-Presenting Cells; Cell Separation; Cyclooxygenase Inhibitors; Female; Hypersensitiv | 1995 |
Macrophage-T cell interaction in experimental visceral leishmaniasis: failure to express costimulatory molecules on Leishmania-infected macrophages and its implication in the suppression of cell-mediated immunity.
Topics: Animals; B7-1 Antigen; Cells, Cultured; Humans; Immunity, Cellular; Indomethacin; Intercellular Adhe | 1995 |
Antigen-specific immunosuppression in visceral leishmaniasis is cell mediated.
Topics: Adolescent; Adult; Aged; Animals; Antigens, Protozoan; Antimony; Cells, Cultured; Child; Dose-Respon | 1989 |
Presence of a macrophage-mediated suppressor cell mechanism during cell-mediated immune response in experimental visceral leishmaniasis.
Topics: Animals; Disease Susceptibility; Immunity, Cellular; Indomethacin; Interferon-gamma; Leishmaniasis, | 1986 |
[Indomethacin and hematopoiesis. Antipyretic and antiphlogistic effects in hemoblastoses and various uncommon diseases].
Topics: Arthritis, Infectious; Arthritis, Rheumatoid; Dermatomyositis; Female; Hematologic Diseases; Hematop | 1968 |