indomethacin has been researched along with Leishmaniasis, American in 6 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cutaneous leishmaniasis is still one of the health problems in Iran and in the region." | 1.35 | Evaluation of anti-leishmanial activity by induction of nitric oxide and inhibition of prostaglandin in Balb/c mice infected with Leishmania major. ( Arjmand, M; Farahmand, M; Ghasemi, F; Hajihosseini, R; Nahrevanian, H, 2009) |
| "Mice treated with indomethacin are responsive to treatment with exogenous IL-12 through at least the first 2 weeks of infection and, unlike control mice treated with IL-12, develop an enhanced Th1-type response associated with increased enhanced resistance to infection." | 1.31 | Combined treatment with interleukin-12 and indomethacin promotes increased resistance in BALB/c mice with established Leishmania major infections. ( Farrell, JP; Li, J; Padigel, UM; Scott, P, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nahrevanian, H | 1 |
| Hajihosseini, R | 1 |
| Arjmand, M | 1 |
| Farahmand, M | 1 |
| Ghasemi, F | 1 |
| Li, J | 1 |
| Padigel, UM | 1 |
| Scott, P | 1 |
| Farrell, JP | 1 |
| Guimarães, ET | 1 |
| Santos, LA | 1 |
| Ribeiro dos Santos, R | 1 |
| Teixeira, MM | 1 |
| dos Santos, WL | 1 |
| Soares, MB | 1 |
| Ajdary, S | 1 |
| Hosseini, MH | 1 |
| Alimohammadian, MH | 1 |
| De Freitas, LA | 1 |
| Mbow, LM | 1 |
| Estay, M | 1 |
| Bleyenberg, JA | 1 |
| Titus, RG | 1 |
| Pérez-Santos, JL | 1 |
| Talamás-Rohana, P | 1 |
6 other studies available for indomethacin and Leishmaniasis, American
| Article | Year |
|---|---|
Evaluation of anti-leishmanial activity by induction of nitric oxide and inhibition of prostaglandin in Balb/c mice infected with Leishmania major.
Topics: Analysis of Variance; Animals; Arginine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; | 2009 |
Combined treatment with interleukin-12 and indomethacin promotes increased resistance in BALB/c mice with established Leishmania major infections.
Topics: Animals; Female; In Vitro Techniques; Indomethacin; Interferon-gamma; Interleukin-12; Leishmania maj | 2002 |
Role of interleukin-4 and prostaglandin E2 in Leishmania amazonensis infection of BALB/c mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Disease Susceptibility; Female; Huma | 2006 |
Recombinant interleukin-1 promotes leishmaniasis in susceptible mice.
Topics: Animals; Disease Progression; Indomethacin; Interleukin-1; Leishmaniasis, Cutaneous; Mice; Mice, Inb | 1997 |
Indomethacin treatment slows disease progression and enhances a Th1 response in susceptible BALB/c mice infected with Leishmania major.
Topics: Animals; Antiprotozoal Agents; Cyclooxygenase Inhibitors; Disease Progression; Female; Immunity, Cel | 1999 |
In vitro indomethacin administration upregulates interleukin-12 production and polarizes the immune response towards a Th1 type in susceptible BALB/c mice infected with Leishmania mexicana.
Topics: Animals; Blotting, Western; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Enzyme- | 2001 |