indomethacin has been researched along with Keratitis in 14 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Keratitis: Inflammation of the cornea.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Regarding superficial punctate keratitis, the corneal tolerance of preservative-free indomethacin 0." | 9.10 | Efficacy of indomethacin 0.1% and fluorometholone 0.1% on conjunctival inflammation following chronic application of antiglaucomatous drugs. ( Allaire, C; Baudouin, C; Creuzot-Garcher, C; Denis, P; Nordmann, JP; Trinquand, C, 2002) |
| "The effect of topically administrated indomethacin was studied in rabbits on an experimentally provoked inflammatory keratitis." | 7.67 | Effect of indomethacin on immunogenic keratitis. ( Barthen, ER; de Wolff-Rouendaal, D; Oosterhuis, JA; van Delft, JL; van Haeringen, NJ, 1986) |
| " Regarding superficial punctate keratitis, the corneal tolerance of preservative-free indomethacin 0." | 5.10 | Efficacy of indomethacin 0.1% and fluorometholone 0.1% on conjunctival inflammation following chronic application of antiglaucomatous drugs. ( Allaire, C; Baudouin, C; Creuzot-Garcher, C; Denis, P; Nordmann, JP; Trinquand, C, 2002) |
| "The effect of topically administrated indomethacin was studied in rabbits on an experimentally provoked inflammatory keratitis." | 3.67 | Effect of indomethacin on immunogenic keratitis. ( Barthen, ER; de Wolff-Rouendaal, D; Oosterhuis, JA; van Delft, JL; van Haeringen, NJ, 1986) |
| "Low doses of indomethacin were applied topically to rabbit eyes in an experimental model of immunologically provoked inflammatory keratitis." | 3.66 | Inhibitors of prostaglandin synthesis and the cornea. ( Barthen, ER; Oosterhuis, JA; van Delft, JL; van Haeringen, NJ, 1983) |
| "Two different chitosan (CS) nanocarriers namely nanoparticles and nanoemulsion were developed to prolong Indomethacin (IM) precorneal residence time and to improve its ocular bioavailability the main limitations in its management of post-operative inflammation and intraocular irritation after cataract extraction." | 1.35 | Chitosan based nanocarriers for indomethacin ocular delivery. ( Badawi, AA; El dally, M; El Mofty, H; El Qidra, RK; El-Laithy, HM, 2008) |
| "Indomethacin-treated eyes showed significantly less inflammatory response, and an insignificantly greater number of antibody-forming cells, than the controls." | 1.26 | Indomethacin and the corneal immune response. ( Belfort, R; Hall, JM; Okumoto, M; Smolin, G, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takkar, B | 1 |
| Khokhar, S | 1 |
| Kumar, U | 1 |
| Venkatesh, P | 1 |
| Badawi, AA | 1 |
| El-Laithy, HM | 1 |
| El Qidra, RK | 1 |
| El Mofty, H | 1 |
| El dally, M | 1 |
| Baudouin, C | 1 |
| Nordmann, JP | 1 |
| Denis, P | 1 |
| Creuzot-Garcher, C | 1 |
| Allaire, C | 1 |
| Trinquand, C | 1 |
| Tuovinen, E | 1 |
| Esilä, R | 1 |
| Liesmaa, M | 1 |
| van Haeringen, NJ | 3 |
| Oosterhuis, JA | 3 |
| van Delft, JL | 3 |
| Barthen, ER | 2 |
| Frucht, J | 1 |
| Zauberman, H | 1 |
| Jager, MJ | 1 |
| Bradley, D | 1 |
| Streilein, JW | 1 |
| Belfort, R | 1 |
| Smolin, G | 1 |
| Hall, JM | 1 |
| Okumoto, M | 1 |
| Girard, LJ | 1 |
| Pichon, P | 1 |
| Moreau, PG | 1 |
| de Wolff-Rouendaal, D | 1 |
| Bolkova, A | 1 |
| Henkind, P | 1 |
| Gold, DH | 1 |
| Watson, PG | 1 |
| Hayreh, SS | 1 |
| Awdry, PN | 1 |
1 review available for indomethacin and Keratitis
| Article | Year |
|---|---|
Ocular manifestations of rheumatic disorders. Natural and iatrogenic.
Topics: Adrenal Cortex Hormones; Arteritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Chloroquine; Conjunc | 1973 |
1 trial available for indomethacin and Keratitis
| Article | Year |
|---|---|
Efficacy of indomethacin 0.1% and fluorometholone 0.1% on conjunctival inflammation following chronic application of antiglaucomatous drugs.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Conjunctiv | 2002 |
12 other studies available for indomethacin and Keratitis
| Article | Year |
|---|---|
Necrotising scleritis, keratitis and uveitis in primary antiphospholipid syndrome.
Topics: Administration, Oral; Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Antiphosphol | 2018 |
Chitosan based nanocarriers for indomethacin ocular delivery.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Area Under Curve; Chemical Phenomen | 2008 |
Experience of the use of indomethacin in inflammatory eye diseases.
Topics: Capsules; Choroiditis; Eye Diseases; Humans; Indomethacin; Iritis; Keratitis; Optic Neuritis; Retini | 1966 |
Inhibitors of prostaglandin synthesis and the cornea.
Topics: Animals; Cornea; Indomethacin; Keratitis; Neovascularization, Pathologic; Prostaglandin Antagonists; | 1983 |
Topical indomethacin effect on neovascularisation of the cornea and on prostaglandin E2 levels.
Topics: Administration, Topical; Animals; Cornea; Dinoprostone; Indomethacin; Keratitis; Neovascularization, | 1984 |
Immunosuppressive properties of cultured human cornea and ciliary body in normal and pathological conditions.
Topics: Aged; Aged, 80 and over; Animals; Cell-Free System; Cells, Cultured; Ciliary Body; Cornea; Culture M | 1995 |
Indomethacin and the corneal immune response.
Topics: Animals; Antibodies; Antibody Formation; Antibody-Producing Cells; Antigens; Aqueous Humor; Cornea; | 1976 |
The effect of topical administration of indomethacin on symptoms in corneal scars and edema.
Topics: Administration, Topical; Castor Oil; Corneal Edema; Drug Carriers; Dry Eye Syndromes; Humans; Indome | 1992 |
[Corneal complications caused by indomethacin eyedrop].
Topics: Adult; Aged; Aged, 80 and over; Corneal Edema; Female; Humans; Indomethacin; Keratitis; Male; Ophtha | 1990 |
Effect of indomethacin on immunogenic keratitis.
Topics: Animals; Cornea; Dexamethasone; Horses; Immune System Diseases; Indomethacin; Keratitis; Rabbits | 1986 |
Enzyme activities in the rabbit cornea during immunogenic keratitis.
Topics: Acetylglucosaminidase; Acid Phosphatase; Animals; Cornea; Horses; Immune System Diseases; Immunizati | 1986 |
Episcleritis and scleritis. II.
Topics: Corneal Opacity; Eye Diseases; Humans; Indomethacin; Inflammation; Keratitis; Oxyphenbutazone; Predn | 1968 |