indomethacin has been researched along with Kahler Disease in 11 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "3 patients with multiple myeloma developed hyperkalemic hypoaldosteronism and renal insufficiency while receiving indomethacin for bone pain." | 7.66 | Indomethacin-induced hyperkalemia and renal failure in multiple myeloma. ( Paladini, G; Tonazzi, C, 1982) |
| "We report the case of a patient with multiple myeloma who developed acute life-threatening water intoxication following treatment with oral indomethacin and low dose intravenous cyclophosphamide." | 3.67 | Life-threatening acute hyponatraemia induced by low dose cyclophosphamide and indomethacin. ( Murray, JA; Webberley, MJ, 1989) |
| "3 patients with multiple myeloma developed hyperkalemic hypoaldosteronism and renal insufficiency while receiving indomethacin for bone pain." | 3.66 | Indomethacin-induced hyperkalemia and renal failure in multiple myeloma. ( Paladini, G; Tonazzi, C, 1982) |
| "Those dilutions of OAF that caused bone resorption had no effect on accumulation of cAMP in rat or mouse calvaria incubated in vitro." | 1.26 | Observations on the mechanism of bone resorption induced by multiple myeloma marrow culture fluids and partially purified osteoclast-activating factor. ( Heersche, JN; Jez, D; Josse, RG; Mundy, GR; Murray, TM, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alexanian, R | 1 |
| Gutterman, J | 1 |
| Levy, H | 1 |
| Josse, RG | 1 |
| Murray, TM | 1 |
| Mundy, GR | 1 |
| Jez, D | 1 |
| Heersche, JN | 1 |
| Sala, P | 1 |
| Tonutti, E | 1 |
| Ruscio, M | 1 |
| Colle, R | 1 |
| Antonutto, G | 1 |
| Falconieri, G | 1 |
| Paladini, G | 1 |
| Tonazzi, C | 1 |
| Quesada, S | 1 |
| Leo, R | 1 |
| Deicher, H | 1 |
| Peest, D | 1 |
| Lu, ZY | 1 |
| Bataille, R | 1 |
| Poubelle, P | 1 |
| Rapp, MJ | 1 |
| Harousseau, JL | 1 |
| Klein, B | 1 |
| Sravan Kumar, G | 1 |
| Das, UN | 1 |
| Dindogru, A | 1 |
| Gailani, S | 1 |
| Henderson, ES | 1 |
| Wallace, HJ | 1 |
| Fitzpatrick, J | 1 |
| Schechter, GP | 1 |
| Wahl, LM | 1 |
| Oppenheim, JJ | 1 |
| Webberley, MJ | 1 |
| Murray, JA | 1 |
| Ophir, R | 1 |
| Ben-Efraim, S | 1 |
| Bonta, IL | 1 |
1 review available for indomethacin and Kahler Disease
| Article | Year |
|---|---|
Suppressor monocytes in human disease: a review.
Topics: Cell Communication; Hodgkin Disease; Humans; Immunity; Immunoglobulins; Immunologic Deficiency Syndr | 1979 |
10 other studies available for indomethacin and Kahler Disease
| Article | Year |
|---|---|
Interferon treatment for multiple myeloma.
Topics: Adult; Aged; Agranulocytosis; Carboxymethylcellulose Sodium; Female; Humans; Indomethacin; Interfero | 1982 |
Observations on the mechanism of bone resorption induced by multiple myeloma marrow culture fluids and partially purified osteoclast-activating factor.
Topics: Aged; Biological Assay; Bone Resorption; Culture Media; Cyclic AMP; Extracellular Space; Female; Hum | 1981 |
IgE myeloma. Report of a new case and review of the literature.
Topics: Aged; Drug Therapy, Combination; Female; Fructose; Humans; Immunoglobulin E; Indomethacin; Leukemia, | 1981 |
Indomethacin-induced hyperkalemia and renal failure in multiple myeloma.
Topics: Acute Kidney Injury; Aged; Female; Humans; Hyperkalemia; Indomethacin; Kidney Function Tests; Male; | 1982 |
Functional and biochemical characteristics of a soluble B lymphocyte proliferation-inhibiting activity produced by bone marrow cells from multiple myeloma patients.
Topics: B-Lymphocytes; Bone Marrow; Humans; Immunosuppressive Agents; Indomethacin; Lymphocyte Activation; M | 1995 |
An interleukin 1 receptor antagonist blocks the IL-1-induced IL-6 paracrine production through a prostaglandin E2-related mechanism in multiple myeloma.
Topics: Animals; Cell Division; Dinoprostone; Humans; In Vitro Techniques; Indomethacin; Interleukin 1 Recep | 1995 |
Cytotoxic action of alpha-linolenic and eicosapentaenoic acids on myeloma cells in vitro.
Topics: alpha-Linolenic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arginine; Calm | 1997 |
Letter: Indomethacin in hypercalcaemia.
Topics: Adenocarcinoma; Calcium; Humans; Hypercalcemia; Indomethacin; Kidney Neoplasms; Multiple Myeloma | 1975 |
Life-threatening acute hyponatraemia induced by low dose cyclophosphamide and indomethacin.
Topics: Aged; Cyclophosphamide; Drug Interactions; Humans; Hyponatremia; Indomethacin; Male; Multiple Myelom | 1989 |
Leukotriene D4 and indomethacin mutually promote the cytostatic activity of macrophages towards tumor cells.
Topics: Animals; Cytotoxicity, Immunologic; In Vitro Techniques; Indomethacin; Macrophage Activation; Mice; | 1987 |