indomethacin has been researched along with Itching in 18 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Skin biopsy showed eosinophilic folliculitis and there was a rapid response to indomethacin." | 3.69 | Pruritic follicular facial rash: eosinophilic folliculitis. ( Kossard, S; Saywell, L, 1997) |
| "The causes of pruritus are numerous including xerosis, drug and photoeruptions, follicular and papular eruptions as well as infestations and infections by a wide range of organisms." | 2.68 | Pruritus in HIV-1 disease: therapy with drugs which may modulate the pattern of immune dysregulation. ( Lee, RB; Skelton, HG; Smith, KJ; Wagner, KF; Yeager, J, 1997) |
| "Atopic dermatitis is a chronic inflammatory disease characterized by severe pruritus, and cutaneous barrier disruption by scratching contributes to further aggravation of the condition." | 1.34 | Cyclooxygenase-1 inhibition delays recovery of the cutaneous barrier disruption caused by mechanical scratching in mice. ( Arai, I; Futaki, N; Hashimoto, Y; Honma, Y; Nakaike, S; Sakurai, T; Sugimoto, M, 2007) |
| "Pretreatment of arachidonic acid increased the skin prostaglandins (prostaglandin D2, prostaglandin E2, prostaglandin F2alpha and 6-keto-prostaglandin F1alpha) contents, but indomethacin decreased the prostaglandin D2 and prostaglandin E2 contents." | 1.32 | Prostanoid DP1 receptor agonist inhibits the pruritic activity in NC/Nga mice with atopic dermatitis. ( Arai, I; Futaki, N; Hashimoto, Y; Inoue, T; Nakaike, S; Sugimoto, M; Takahashi, N; Takano, N, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (33.33) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Choi, JK | 1 |
| Kim, KM | 1 |
| Kim, DK | 1 |
| Yeom, MH | 1 |
| Koh, JY | 1 |
| Jung, SJ | 1 |
| Kim, HJ | 1 |
| Oh, SH | 1 |
| Kim, SY | 1 |
| Lee, CH | 1 |
| Zhu, Y | 1 |
| Wang, XR | 1 |
| Peng, C | 1 |
| Xu, JG | 1 |
| Liu, YX | 1 |
| Wu, L | 1 |
| Zhu, QG | 1 |
| Liu, JY | 1 |
| Li, FQ | 1 |
| Pan, YH | 1 |
| You, BM | 1 |
| Hu, JH | 1 |
| Arai, I | 3 |
| Takano, N | 1 |
| Hashimoto, Y | 3 |
| Futaki, N | 3 |
| Sugimoto, M | 3 |
| Takahashi, N | 1 |
| Inoue, T | 1 |
| Nakaike, S | 3 |
| Honma, Y | 2 |
| Tanaka, M | 1 |
| Fallah, H | 1 |
| Dunlop, K | 1 |
| Kossard, S | 2 |
| Sakurai, T | 1 |
| Kuraishi, Y | 2 |
| Ohtsuka, E | 1 |
| Nakano, T | 1 |
| Kawai, S | 1 |
| Andoh, T | 2 |
| Nojima, H | 1 |
| Kamimura, K | 1 |
| Fjellner, B | 1 |
| Hägermark, O | 1 |
| Awadzi, K | 1 |
| Orme, ML | 1 |
| Breckenridge, AM | 1 |
| Gilles, HM | 1 |
| Nishijima, S | 1 |
| Sugiyama, T | 1 |
| Nakagawa, M | 1 |
| Odaka, T | 1 |
| Takaishi, K | 1 |
| Saywell, L | 1 |
| Smith, KJ | 1 |
| Skelton, HG | 1 |
| Yeager, J | 1 |
| Lee, RB | 1 |
| Wagner, KF | 1 |
| Katsube, N | 1 |
| Maruyama, M | 1 |
| Bigby, M | 1 |
| Stern, R | 1 |
| Almeyda, J | 1 |
| Baker, H | 1 |
| Caruso, I | 1 |
| Silberman, HR | 1 |
| McGinn, TG | 1 |
| Kremer, WB | 1 |
2 reviews available for indomethacin and Itching
| Article | Year |
|---|---|
Cutaneous reactions to nonsteroidal anti-inflammatory drugs. A review.
Topics: Acetates; Anti-Inflammatory Agents; Aspirin; Drug Eruptions; Humans; Ibuprofen; Indomethacin; ortho- | 1985 |
Drug reactions. XII. Cutaneous reactions to anti-rheumatic drugs.
Topics: Adult; Anti-Inflammatory Agents; Drug Eruptions; Edema; Female; Gold; Humans; Indomethacin; Lymphade | 1970 |
2 trials available for indomethacin and Itching
| Article | Year |
|---|---|
The chemotherapy of onchocerciasis VI. The effect of indomethacin and cyproheptadine on the Mazzotti reaction.
Topics: Adult; Clinical Trials as Topic; Cyproheptadine; Diethylcarbamazine; Double-Blind Method; Humans; Hy | 1982 |
Pruritus in HIV-1 disease: therapy with drugs which may modulate the pattern of immune dysregulation.
Topics: Administration, Cutaneous; Administration, Topical; Anti-Inflammatory Agents; Antipruritics; Cycloox | 1997 |
14 other studies available for indomethacin and Itching
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Topical anti-inflammatory and antipruritic effects of Alpinia katsumadai extracts.
Topics: Administration, Topical; Alpinia; Animals; Anti-Inflammatory Agents; Antipruritics; Disease Models, | 2009 |
Induction of leukotriene B(4) and prostaglandin E(2) release from keratinocytes by protease-activated receptor-2-activating peptide in ICR mice.
Topics: Animals; Cetirizine; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Hydroxyurea; | 2009 |
Prostanoid DP1 receptor agonist inhibits the pruritic activity in NC/Nga mice with atopic dermatitis.
Topics: 6-Ketoprostaglandin F1 alpha; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachid | 2004 |
Prostaglandin D2 and prostaglandin E2 accelerate the recovery of cutaneous barrier disruption induced by mechanical scratching in mice.
Topics: 6-Ketoprostaglandin F1 alpha; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinopro | 2005 |
Successful treatment of recalcitrant necrotizing eosinophilic folliculitis using indomethacin and cephalexin.
Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cephalexin; Di | 2006 |
Cyclooxygenase-1 inhibition delays recovery of the cutaneous barrier disruption caused by mechanical scratching in mice.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; | 2007 |
Possible involvement of 5-lipoxygenase metabolite in itch-associated response of mosquito allergy in mice.
Topics: Animals; Arachidonate 5-Lipoxygenase; Betamethasone Valerate; Bridged Bicyclo Compounds, Heterocycli | 2007 |
Potentiation of histamine-induced itch and flare responses in human skin by the enkephalin analogue FK-33-824, beta-endorphin and morphine.
Topics: Adolescent; Adult; beta-Endorphin; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dinoprostone; Drug Synerg | 1982 |
Two cases of eosinophilic pustular folliculitis treated by acemetacin.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Back; Eosinophilia; Facial Dermatoses; Female; Folli | 1994 |
Pruritic follicular facial rash: eosinophilic folliculitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Eosinophilia; Facial Dermatoses; Female; Folliculiti | 1997 |
Involvement of leukotriene B(4) in substance P-induced itch-associated response in mice.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors | 2001 |
[Undesired collateral effects of antirheumatic drugs: indomethacin].
Topics: Arthritis, Rheumatoid; Drug Eruptions; Gastrointestinal Diseases; Headache; Humans; Indomethacin; Pa | 1972 |
Control of fever in Hodgkin's disease by indomethacin.
Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Aspirin; Female; Fever | 1965 |