Page last updated: 2024-10-29

indomethacin and Interstitial Nephritis

indomethacin has been researched along with Interstitial Nephritis in 9 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"We describe three patients in whom severe, life-threatening hyperkalemia and renal insufficiency developed after treatment of acute gouty arthritis with indomethacin."7.66Indomethacin-induced hyperkalemia in three patients with gouty arthritis. ( Beckstrom, D; Findling, JW; Itskovitz, H; Kozin, F; Rawsthorne, L, 1980)
"We report a case of reversible acute renal failure associated with indomethacin therapy."5.27Reversible acute interstitial nephritis associated with indomethacin. ( Barzilai, D; Better, OS; Green, J; Yoffe, B, 1985)
"We describe three patients in whom severe, life-threatening hyperkalemia and renal insufficiency developed after treatment of acute gouty arthritis with indomethacin."3.66Indomethacin-induced hyperkalemia in three patients with gouty arthritis. ( Beckstrom, D; Findling, JW; Itskovitz, H; Kozin, F; Rawsthorne, L, 1980)
"Although scleritis has not been reported as a tubulointerstitial nephritis-associated ocular inflammation, it may be part of the possible spectrum of ocular inflammation occurring as part of the TINU syndrome."1.33Recurrent nodular scleritis preceding an adult TINU syndrome. ( Daniel, E; Gangaputra, S; Jabs, DA; Kempen, JH, 2006)
"We report a case of reversible acute renal failure associated with indomethacin therapy."1.27Reversible acute interstitial nephritis associated with indomethacin. ( Barzilai, D; Better, OS; Green, J; Yoffe, B, 1985)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zuo, Y1
Ma, J1
Gu, Y1
Yang, H1
Lin, S1
Daniel, E1
Gangaputra, S1
Kempen, JH1
Jabs, DA1
Findling, JW1
Beckstrom, D1
Rawsthorne, L1
Kozin, F1
Itskovitz, H1
Sakai, N1
Wada, T1
Shimizu, M1
Segawa, C1
Furuichi, K1
Kobayashi, Ki1
Yokoyama, H1
Carmichael, J1
Shankel, SW1
Schwarz, A1
Krause, PH1
Keller, F1
Offermann, G1
Mihatsch, MJ1
Handa, SP1
Reeves, WB1
Foley, RJ1
Weinman, EJ1
Green, J1
Yoffe, B1
Barzilai, D1
Better, OS1

Reviews

2 reviews available for indomethacin and Interstitial Nephritis

ArticleYear
Effects of nonsteroidal anti-inflammatory drugs on prostaglandins and renal function.
    The American journal of medicine, 1985, Volume: 78, Issue:6 Pt 1

    Topics: Anti-Inflammatory Agents; Aspirin; Epoprostenol; Fenoprofen; Glafenine; Glomerular Filtration Rate;

1985
Granulomatous interstitial nephritis after nonsteroidal anti-inflammatory drugs.
    American journal of nephrology, 1988, Volume: 8, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Indomethacin; Ketoprofen

1988

Other Studies

7 other studies available for indomethacin and Interstitial Nephritis

ArticleYear
[The renal protective effect of selective cyclooxygenase-2 inhibitor on obstructive nephropathy].
    Zhonghua nei ke za zhi, 2002, Volume: 41, Issue:12

    Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, A

2002
Recurrent nodular scleritis preceding an adult TINU syndrome.
    Ocular immunology and inflammation, 2006, Volume: 14, Issue:4

    Topics: Acute Disease; Female; Glucocorticoids; Humans; Indomethacin; Middle Aged; Nephritis, Interstitial;

2006
Indomethacin-induced hyperkalemia in three patients with gouty arthritis.
    JAMA, 1980, Sep-05, Volume: 244, Issue:10

    Topics: Acute Disease; Acute Kidney Injury; Aged; Diabetes Mellitus; Female; Gout; Humans; Hyperkalemia; Ind

1980
Tubulointerstitial nephritis with anti-neutrophil cytoplasmic antibody following indomethacin treatment.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:11

    Topics: Aged; Aged, 80 and over; Antibodies, Antineutrophil Cytoplasmic; Humans; Indomethacin; Kidney Tubule

1999
Drug-induced acute interstitial nephritis: report of 10 cases.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1986, Dec-01, Volume: 135, Issue:11

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory

1986
Nephrotoxicity from nonsteroidal anti-inflammatory drugs.
    Southern medical journal, 1985, Volume: 78, Issue:3

    Topics: Acute Disease; Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Aspirin; Female; Humans; Hyperka

1985
Reversible acute interstitial nephritis associated with indomethacin.
    Israel journal of medical sciences, 1985, Volume: 21, Issue:2

    Topics: Acute Kidney Injury; Atrophy; Female; Glomerular Mesangium; Humans; Indomethacin; Kidney Tubules; Mi

1985