Page last updated: 2024-10-29

indomethacin and Inflammation, Endodontic

indomethacin has been researched along with Inflammation, Endodontic in 7 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"In a randomized double-blinded clinical trial, 150 patients (50 per group) with irreversible pulpitis were given placebo, 600 mg ibuprofen, or 75 mg indomethacin 1 hour before local anesthesia."9.14The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis. ( Abbott, PV; Ashouri, R; Askarifard, S; Nakhaee, N; Pardakhti, A; Parirokh, M; Rekabi, AR, 2010)
"In a randomized double-blinded clinical trial, 150 patients (50 per group) with irreversible pulpitis were given placebo, 600 mg ibuprofen, or 75 mg indomethacin 1 hour before local anesthesia."5.14The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis. ( Abbott, PV; Ashouri, R; Askarifard, S; Nakhaee, N; Pardakhti, A; Parirokh, M; Rekabi, AR, 2010)
"Following the induction of experimental pulpitis in baboon teeth, calf skin collagen, indomethacin, or zinc oxide-eugenol was used to dress exposed dental pulp wounds in selected teeth."3.67The effect of collagen and indomethacin on inflamed dental pulp wounds of baboon teeth. ( Dover, MS; Franklin, CJ; Oguntebi, BR; Tuwaijri, AS, 1988)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Parirokh, M1
Ashouri, R1
Rekabi, AR1
Nakhaee, N1
Pardakhti, A1
Askarifard, S1
Abbott, PV1
Benoliel, R1
Sharav, Y1
Ohnishi, T1
Suwa, M1
Oyama, T1
Arakaki, N1
Torii, M1
Daikuhara, Y1
Lin, SK1
Kuo, MY1
Wang, JS1
Lee, JJ1
Wang, CC1
Huang, S1
Shun, CT1
Hong, CY1
Okiji, T2
Morita, I2
Sunada, I2
Murota, S2
Oguntebi, BR1
Dover, MS1
Franklin, CJ1
Tuwaijri, AS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Electroacupuncture (EA) on the Success of Inferior Alveolar Nerve Block (IANB) and Post-operative Pain Relief in Mandibular Molar With Symptomatic Irreversible Pulpitis (SIP) Among Malaysians: A Study Protocol for Randomized Double-Blinded C[NCT04804761]20 participants (Anticipated)Interventional2023-01-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for indomethacin and Inflammation, Endodontic

ArticleYear
Paroxysmal hemicrania. Case studies and review of the literature.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1998, Volume: 85, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Cluster Headache; Conjunctiva

1998

Trials

1 trial available for indomethacin and Inflammation, Endodontic

ArticleYear
The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis.
    Journal of endodontics, 2010, Volume: 36, Issue:9

    Topics: Adult; Analysis of Variance; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-S

2010

Other Studies

5 other studies available for indomethacin and Inflammation, Endodontic

ArticleYear
Prostaglandin E2 predominantly induces production of hepatocyte growth factor/scatter factor in human dental pulp in acute inflammation.
    Journal of dental research, 2000, Volume: 79, Issue:2

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Cells, Cultured; Chi

2000
Differential regulation of interleukin-6 and inducible cyclooxygenase gene expression by cytokines through prostaglandin-dependent and -independent mechanisms in human dental pulp fibroblasts.
    Journal of endodontics, 2002, Volume: 28, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Cells, Cultured; Cyclooxygenase 2; Cycl

2002
The role of leukotriene B4 in neutrophil infiltration in experimentally-induced inflammation of rat tooth pulp.
    Journal of dental research, 1991, Volume: 70, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Cell Movement; Cyclophosphami

1991
Involvement of arachidonic acid metabolites in increases in vascular permeability in experimental dental pulpal inflammation in the rat.
    Archives of oral biology, 1989, Volume: 34, Issue:7

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid;

1989
The effect of collagen and indomethacin on inflamed dental pulp wounds of baboon teeth.
    Oral surgery, oral medicine, and oral pathology, 1988, Volume: 65, Issue:2

    Topics: Animals; Collagen; Dental Pulp; Dental Pulp Necrosis; Dentin, Secondary; Indomethacin; Papio; Pulpit

1988