indomethacin has been researched along with Infantile Respiratory Distress Syndrome in 86 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sequential bleeding times were performed on 25 preterm infants receiving intravenous indomethacin for closure of the patent ductus arteriosus." | 7.67 | Prolonged bleeding time in preterm infants receiving indomethacin for patent ductus arteriosus. ( Bejar, R; Corazza, MS; Cvetnic, W; Davis, RF; Merritt, TA, 1984) |
| "Ibuprofen therapy on the third day of life is as efficacious as indomethacin for the treatment of patent ductus arteriosus in preterm infants with the respiratory distress syndrome and is significantly less likely to induce oliguria." | 5.09 | A comparison of ibuprofen and indomethacin for closure of patent ductus arteriosus. ( Degroote, K; Langhendries, JP; Lecoutere, D; Smets, K; Van de Broek, H; Van Overmeire, B; Weyler, J, 2000) |
| " Magnesium sulfate administration, steroid administration, maternal diabetes mellitus, gestational age at delivery, indomethacin exposure, birthweight, and chorioamnionitis were all considered as possible covariates in the multivariable regression models." | 3.83 | Effect of obesity on neonatal outcomes in pregnancies with preterm premature rupture of membranes. ( DeWitt, PE; Faucett, AM; Gibbs, RS; Metz, TD, 2016) |
| "Our objective was to determine the effect of chorioamnionitis on plasma prostaglandin E2 (PGE2) and thromboxane B2 (TxB2) during the first week in preterm infants." | 3.74 | Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants. ( Aranda, JV; Glibetic, M; Natarajan, G; Thomas, RL, 2008) |
| "There were no significant differences between the indomethacin-exposed infants and control infants in birth weight, Apgar scores, frequency of cesarean section deliveries, and multiple gestation." | 3.72 | Neonatal outcome after exposure to indomethacin in utero: a retrospective case cohort study. ( Abbasi, S; Gerdes, JS; Ludmir, J; Samimi, SS; Sehdev, HM, 2003) |
| "Sequential bleeding times were performed on 25 preterm infants receiving intravenous indomethacin for closure of the patent ductus arteriosus." | 3.67 | Prolonged bleeding time in preterm infants receiving indomethacin for patent ductus arteriosus. ( Bejar, R; Corazza, MS; Cvetnic, W; Davis, RF; Merritt, TA, 1984) |
| "Tocolysis in advanced preterm labor delays delivery by more than 48 hours in 50% of patients." | 2.68 | Tocolysis in advanced preterm labor: impact on neonatal outcome. ( Barke, JI; de Veciana, M; Major, CA; Porto, M, 1995) |
| "Aspirin (ASA) is an alternative, but there are no controlled trials on its efficacy." | 2.68 | Aspirin versus indomethacin treatment of patent ductus arteriosus in preterm infants with respiratory distress syndrome. ( Brus, F; Elzenga, NJ; Okken, A; Schasfoort, M; van Acker, KJ; van der Auwera, JC; van Overmeire, B, 1995) |
| "Ibuprofen treatment seems to be as efficient as indomethacin in closing PDA on the third day of life in preterm infants with respiratory distress syndrome and seems to have fewer renal side effects." | 2.68 | Treatment of patent ductus arteriosus with ibuprofen. ( Creten, WL; Follens, I; Hartmann, S; Van Acker, KJ; Van Overmeire, B, 1997) |
| "Prophylactic closure of the patent ductus arteriosus (PDA) has been recommended as a means of decreasing early respiratory distress, and thereby chronic respiratory sequelae in the very low birth weight (VLBW) neonate." | 2.66 | Failure of prophylactic indomethacin to improve the outcome of the very low birth weight infant. ( Bui, K; Hammerman, C; Komar, K; Strates, E, 1987) |
| "The 75% patent ductus arteriosus closure rate with indomethacin treatment in phase 1 was not statistically significant due to a 44% spontaneous closure rate in the control group." | 2.65 | Indomethacin treatment for symptomatic patent ductus arteriosus: a double-blind control study. ( Aziz, KU; Hunt, CE; Newfeld, EA; Wilson, A; Yanagi, RM, 1981) |
| "Indomethacin has several adverse effects, the most common of which is renal failure." | 2.49 | Clinical pharmacology of indomethacin in preterm infants: implications in patent ductus arteriosus closure. ( Pacifici, GM, 2013) |
| "The effect of surfactant administration for respiratory distress syndrome (RDS) on indomethacin (INDO) pharmacodynamics and dosing requirements for patent ductus arteriosus (PDA) closure and renal toxicity was evaluated." | 1.36 | Indomethacin pharmacodynamics are altered by surfactant: a possible challenge to current indomethacin dosing guidelines created before surfactant availability. ( Carlos, RQ; Davonzo, C; Dimaguila, MA; Gal, P; McPherson, C; Ransom, JL; Smith, M; Wimmer, JE, 2010) |
| "Respiratory distress and patent ductus arteriosus (PDA) in neonates are mutually perpetuating." | 1.36 | Management of patent ductus arteriosus in term or near-term neonates with respiratory distress. ( Chen, TJ; Chung, HT; Huang, HR; Lien, R; Lin, YC; Liu, WH; Su, WJ; Yang, PH, 2010) |
| "To test the hypothesis that patent ductus arteriosus that fail to close with prostaglandin inhibition may be regulated by mechanisms that act independently of prostaglandin production." | 1.34 | Risk factors for persistent ductus arteriosus patency during indomethacin treatment. ( Chorne, N; Clyman, RI; Jegatheesan, P; Lin, E; Shi, R, 2007) |
| "We confirm that lower indomethacin treatment of patent ductus arteriosus in premature neonates are as effective as standard protocols." | 1.31 | Minimal effective dose of indomethacin for the treatment of patent ductus arteriosus in preterm infants. ( Babre, F; Demarquez, JL; Dumas de la Roque, E; Fayon, M; Pedespan, L, 2002) |
| "Only one patient had recurrence of the PDA, and the PDA was closed again in this case without problems using the same regimen." | 1.29 | Treatment of patent ductus arteriosus with low-dose indomethacin in very low birth weight neonates with impairment of renal function: report of three cases. ( Kuo, CY, 1996) |
| "Infants with a symptomatic patent ductus arteriosus had lower LTV than controls with the same severity of RDS." | 1.28 | The influence of respiratory distress syndrome on heart rate variability in very preterm infants. ( Hopman, JC; Kollée, LA; Stoelinga, GB; van Amen, JP; van Geijn, HP; van Ravenswaaij-Arts, CM, 1991) |
| "Indomethacin was administered at a dosage of 0." | 1.28 | Closure of the ductus arteriosus with indomethacin in ventilated neonates with respiratory distress syndrome. Effects of pulmonary compliance and ventilation. ( Abbasi, S; Bhutani, VK; Esterly, KL; Pearlman, SA; Spear, ML; Stefano, JL, 1991) |
| "The incidence and evolution of patent ductus arteriosus (PDA) was evaluated in twins and preterm singletons with birth weight less than or equal to 1750 g admitted to our Department in 1987 for respiratory distress syndrome (RDS)." | 1.28 | Does the respiratory distress syndrome in twins and singletons run different risks of persistent ductus arteriosus? ( Foti, P; Milanesi, O; Stellin, G; Trevisanuto, D; Zambon, P; Zanardo, V, 1989) |
| " The margin between closure of the ductus arteriosus and the deterioration of kidney function in preterm infants treated with a presently recommended indomethacin dosage is too narrow." | 1.27 | [Therapeutic problems with indomethacin in preterm infants with persistent ductus arteriosus]. ( Müller, H; Plückthun, H; Seyberth, HW; Ulmer, HE; Wille, L; Wolf, D, 1983) |
| "Indomethacin treatment may augment lung inflammation and fibrosis by increasing BAL elastase activity and fibronectin concentration." | 1.27 | Effects of dexamethasone and indomethacin on elastase, alpha 1-proteinase inhibitor, and fibronectin in bronchoalveolar lavage fluid from neonates. ( Gerdes, JS; Harris, MC; Polin, RA, 1988) |
| "Issues of the pharmacologic therapy of preterm labor, enhancement of lung maturity, and management of labor and delivery are discussed." | 1.27 | Obstetric management of the very low birth weight fetus. ( Hayashi, RH; Marshall, CL, 1986) |
| " However, the margin between closure of the ductus arteriosus and the deterioration of kidney function in preterm infants treated with a presently recommended indomethacin dosage was narrow." | 1.26 | Recovery of prostaglandin production associated with reopening of the ductus arteriosus after indomethacin treatment in preterm infants with respiratory distress syndrome. ( Müller, H; Plückthun, H; Seyberth, HW; Ulmer, HE; Wille, L; Wolf, D, 1982) |
| "Fifteen preterm infants with patent ductus arteriosus and respiratory distress syndrome were given indomethacin (0." | 1.26 | Variability of serum indomethacin concentrations after oral and intravenous administration to preterm infants. ( Imbeck, H; Mrongovius, R; Müller, H; Seyberth, HW; Wille, L, 1982) |
| "Our present policy for patent ductus arteriosus with respiratory distress syndrome in the premature baby is to initiate early treatment with indomethacin." | 1.26 | Management of patent ductus arteriosus in preterm babies. ( Alvarez, F; Burgueros, M; Gómez, R; Moreno, F; Quero, J; Sanchez, PA, 1980) |
| "Indomethacin was used orally 12 of these patients without effect to close the ductus." | 1.26 | [Ductus ligation in idiopathic respiratory distress syndrome of the premature infant]. ( Beitzke, A; Metzler, W; Müller, WD; Rigler, B; Schober, P, 1980) |
| "Patent ductus arteriosus was diagnosed in 239 neonates of low birth weight (less than 2500 g) referred to the Hospital for Sick Children in a 21/2-year period." | 1.26 | Patent ductus arteriosus in infants of low birth weight. ( Cook, DH; Izukawa, T; Olley, PM; Rowe, RD; Smith, DR; Swyer, PR, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (52.33) | 18.7374 |
| 1990's | 19 (22.09) | 18.2507 |
| 2000's | 14 (16.28) | 29.6817 |
| 2010's | 8 (9.30) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pacifici, GM | 1 |
| Lee, HC | 1 |
| Durand, DJ | 1 |
| Danielsen, B | 1 |
| Dueñas, GV | 1 |
| Powers, RJ | 1 |
| Faucett, AM | 1 |
| Metz, TD | 1 |
| DeWitt, PE | 1 |
| Gibbs, RS | 1 |
| Haw, MP | 1 |
| Natarajan, G | 1 |
| Glibetic, M | 1 |
| Thomas, RL | 1 |
| Aranda, JV | 1 |
| McPherson, C | 1 |
| Gal, P | 1 |
| Ransom, JL | 1 |
| Carlos, RQ | 1 |
| Dimaguila, MA | 1 |
| Smith, M | 1 |
| Davonzo, C | 1 |
| Wimmer, JE | 1 |
| Benitz, WE | 1 |
| Lin, YC | 1 |
| Huang, HR | 1 |
| Lien, R | 1 |
| Yang, PH | 1 |
| Su, WJ | 1 |
| Chung, HT | 1 |
| Chen, TJ | 1 |
| Liu, WH | 1 |
| Heo, MJ | 1 |
| Lee, OS | 1 |
| Lim, SC | 1 |
| Seyberth, HW | 5 |
| Müller, H | 4 |
| Wille, L | 4 |
| Plückthun, H | 2 |
| Wolf, D | 2 |
| Ulmer, HE | 3 |
| Abbasi, S | 2 |
| Gerdes, JS | 2 |
| Sehdev, HM | 1 |
| Samimi, SS | 1 |
| Ludmir, J | 1 |
| Su, PH | 1 |
| Chen, JY | 1 |
| Su, CM | 1 |
| Huang, TC | 1 |
| Lee, HS | 1 |
| Lubetzky, R | 1 |
| Mandel, D | 1 |
| Mimouni, FB | 1 |
| Diamant, S | 1 |
| Birger, A | 1 |
| Barak, M | 1 |
| Dollberg, S | 1 |
| Distefano, G | 1 |
| Hasan, SU | 1 |
| Farkouh, CR | 1 |
| Merrill, JD | 1 |
| Ballard, PL | 1 |
| Ballard, RA | 1 |
| Ischiropoulos, H | 1 |
| Lorch, SA | 1 |
| Chorne, N | 1 |
| Jegatheesan, P | 1 |
| Lin, E | 1 |
| Shi, R | 1 |
| Clyman, RI | 1 |
| Kääpä, P | 1 |
| Lanning, P | 1 |
| Koivisto, M | 1 |
| Mansani, FE | 1 |
| Caltabiano, M | 1 |
| Gazza, F | 1 |
| Petersen, S | 2 |
| Christensen, NC | 2 |
| Lauridsen, P | 2 |
| Pedersen, SA | 2 |
| Ryssing, E | 2 |
| Zerella, JT | 1 |
| Spies, RJ | 1 |
| Deaver, DC | 1 |
| Dailry, WJ | 1 |
| Haple, DC | 1 |
| Trump, DS | 1 |
| Barnes, AD | 1 |
| Biskinis, E | 1 |
| Tupulur, I | 1 |
| Toot, PJ | 1 |
| Corazza, MS | 1 |
| Davis, RF | 1 |
| Merritt, TA | 6 |
| Bejar, R | 1 |
| Cvetnic, W | 1 |
| Strauss, A | 1 |
| Modanlou, HD | 1 |
| Gyepes, M | 1 |
| Wittner, R | 1 |
| Jacob, J | 1 |
| Gluck, L | 3 |
| DiSessa, T | 1 |
| Edwards, D | 1 |
| Kulovich, M | 1 |
| Kurlinski, J | 1 |
| Friedman, WF | 4 |
| Kitterman, JA | 1 |
| Harris, JP | 1 |
| Roghmann, K | 1 |
| Wood, B | 1 |
| Campanella, V | 1 |
| Alexson, C | 1 |
| Manning, J | 1 |
| Shapiro, DL | 1 |
| Yanagi, RM | 1 |
| Wilson, A | 1 |
| Newfeld, EA | 1 |
| Aziz, KU | 1 |
| Hunt, CE | 1 |
| Hencz, P | 1 |
| Kertész, E | 1 |
| Beviz, J | 1 |
| Szeleczki, T | 1 |
| Szekeres, Z | 1 |
| White, CL | 1 |
| Coen, RW | 1 |
| Rosenberg, M | 1 |
| Mrongovius, R | 1 |
| Imbeck, H | 1 |
| Jaso, E | 1 |
| Tejedor, JC | 1 |
| Quero, J | 2 |
| Pérez Rodríguez, J | 1 |
| Agustí, B | 1 |
| Castro, J | 1 |
| García Frías, E | 1 |
| Frisch, H | 1 |
| Hammerer, I | 1 |
| Heinz-Erian, P | 1 |
| Gschnitzer, F | 1 |
| Lozano González, CH | 1 |
| Holden, AM | 1 |
| Hurtado del Río, D | 1 |
| Segura, MA | 1 |
| Oh, W | 1 |
| Gómez, R | 1 |
| Moreno, F | 1 |
| Burgueros, M | 1 |
| Sanchez, PA | 1 |
| Alvarez, F | 1 |
| Molina, V | 1 |
| Krauel, J | 1 |
| Baraibar, R | 1 |
| Campistol, J | 1 |
| Beitzke, A | 2 |
| Rigler, B | 1 |
| Müller, WD | 2 |
| Metzler, W | 1 |
| Schober, P | 1 |
| Smith, DR | 1 |
| Cook, DH | 1 |
| Izukawa, T | 1 |
| Olley, PM | 1 |
| Swyer, PR | 1 |
| Rowe, RD | 1 |
| de Veciana, M | 1 |
| Porto, M | 1 |
| Major, CA | 1 |
| Barke, JI | 1 |
| Varsila, E | 1 |
| Hallman, M | 1 |
| Venge, P | 1 |
| Andersson, S | 1 |
| van Overmeire, B | 5 |
| Brus, F | 1 |
| van Acker, KJ | 2 |
| van der Auwera, JC | 1 |
| Schasfoort, M | 1 |
| Elzenga, NJ | 1 |
| Okken, A | 1 |
| Cleary, GM | 1 |
| Higgins, ST | 1 |
| Merton, DA | 1 |
| Cullen, JA | 1 |
| Gottlieb, RP | 1 |
| Baumgart, S | 1 |
| Gardner, MO | 1 |
| Owen, J | 1 |
| Skelly, S | 1 |
| Hauth, JC | 1 |
| Yaseen, H | 1 |
| al Umran, K | 1 |
| Ali, H | 1 |
| Rustum, M | 1 |
| Darwich, M | 1 |
| al-Faraidy, A | 1 |
| Kuo, CY | 1 |
| Follens, I | 1 |
| Hartmann, S | 1 |
| Creten, WL | 1 |
| Slootmaekers, V | 1 |
| De Loor, J | 1 |
| Buytaert, P | 1 |
| Hagendorens, M | 1 |
| Sys, SU | 1 |
| Van Reempts, PJ | 1 |
| Soll, RF | 1 |
| Andruscavage, L | 1 |
| Horigome, H | 1 |
| Szebeni, J | 1 |
| Fontana, JL | 1 |
| Wassef, NM | 1 |
| Mongan, PD | 1 |
| Morse, DS | 1 |
| Dobbins, DE | 1 |
| Stahl, GL | 1 |
| Bünger, R | 1 |
| Alving, CR | 1 |
| Trevisanuto, D | 3 |
| Zaninotto, M | 1 |
| Lachin, M | 1 |
| Altinier, S | 1 |
| Plebani, M | 1 |
| Ferrarese, P | 1 |
| Zanardo, V | 3 |
| Smets, K | 1 |
| Lecoutere, D | 1 |
| Van de Broek, H | 2 |
| Weyler, J | 2 |
| Degroote, K | 1 |
| Langhendries, JP | 1 |
| Van Laer, P | 1 |
| Vanhaesebrouck, P | 1 |
| Weintraub, Z | 1 |
| Solovechick, M | 1 |
| Reichman, B | 1 |
| Rotschild, A | 1 |
| Waisman, D | 1 |
| Davkin, O | 1 |
| Lusky, A | 1 |
| Bental, Y | 1 |
| Dumas de la Roque, E | 1 |
| Fayon, M | 1 |
| Babre, F | 1 |
| Demarquez, JL | 1 |
| Pedespan, L | 1 |
| Harrold, J | 1 |
| Schmidt, B | 1 |
| DiSessa, TG | 1 |
| Feldman, BH | 2 |
| Kirkpatrick, SE | 1 |
| Fitzpatrick, KM | 1 |
| Bhat, R | 1 |
| Vidyasagar, D | 1 |
| Vadapalli, M | 1 |
| Whalley, C | 1 |
| Fisher, E | 1 |
| Hastreiter, A | 1 |
| Evans, M | 1 |
| Zach, M | 1 |
| Stix, H | 1 |
| Rosegger, H | 1 |
| Gersony, WM | 2 |
| Fuller, WE | 1 |
| Heymann, MA | 1 |
| Hoffman, JI | 1 |
| Neal, WA | 1 |
| Kyle, JM | 1 |
| Mullett, MD | 1 |
| Bavoux, F | 1 |
| Balsan, MJ | 1 |
| Jones, JG | 1 |
| Guthrie, RD | 1 |
| Cotton, RB | 2 |
| Haywood, JL | 1 |
| FitzGerald, GA | 1 |
| van Ravenswaaij-Arts, CM | 1 |
| Hopman, JC | 1 |
| Kollée, LA | 1 |
| van Amen, JP | 1 |
| Stoelinga, GB | 1 |
| van Geijn, HP | 1 |
| Reller, MD | 1 |
| Buffkin, DC | 1 |
| Colasurdo, MA | 1 |
| Rice, MJ | 1 |
| McDonald, RW | 1 |
| Milanesi, O | 2 |
| Rizzo, M | 1 |
| Ronconi, M | 1 |
| Stellin, G | 2 |
| Cantarutti, F | 1 |
| Stefano, JL | 1 |
| Pearlman, SA | 1 |
| Spear, ML | 1 |
| Esterly, KL | 1 |
| Bhutani, VK | 1 |
| Harris, MC | 1 |
| Polin, RA | 1 |
| Foti, P | 1 |
| Zambon, P | 1 |
| Weesner, KM | 1 |
| Dillard, RG | 1 |
| Boyle, RJ | 1 |
| Block, SM | 1 |
| Pongiglione, G | 1 |
| Marasini, M | 1 |
| Silvestri, G | 1 |
| Tuo, P | 1 |
| Ribaldone, D | 1 |
| Bertolini, A | 1 |
| Garello-Cantoni, L | 1 |
| Hammerman, C | 1 |
| Strates, E | 1 |
| Komar, K | 1 |
| Bui, K | 1 |
| Marshall, CL | 1 |
| Hayashi, RH | 1 |
| Vargas-Origel, A | 1 |
| Cruz-Anguiano, V | 1 |
| López-Montaño, E | 1 |
| Dudley, DK | 1 |
| Hardie, MJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Combination of Acetaminophen and Ibuprofen in the Management of Patent Ductus Arteriosus in Premature Infants: A Pilot Study[NCT03103022] | Phase 1 | 20 participants (Actual) | Interventional | 2017-06-12 | Completed | ||
| Physiological Disturbances Associated With Neonatal Intraventricular Hemorrhage[NCT00665769] | 103 participants (Actual) | Interventional | 2008-06-30 | Terminated (stopped due to Recruitment was proceeding too slowly) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for indomethacin and Infantile Respiratory Distress Syndrome
| Article | Year |
|---|---|
Clinical pharmacology of indomethacin in preterm infants: implications in patent ductus arteriosus closure.
Topics: Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity; Ductus Arteriosus, Patent | 2013 |
Surgical Intervention in Preterm Neonates with Patent Ductus Arteriosus.
Topics: Bronchopulmonary Dysplasia; Combined Modality Therapy; Cyclooxygenase Inhibitors; Ductus Arteriosus, | 2016 |
Treatment of persistent patent ductus arteriosus in preterm infants: time to accept the null hypothesis?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiac Surgical Procedures; Confidence Intervals; Ductus A | 2010 |
[The pharmacological manipulation of Botallo's duct in the duct-dependent congenital cardiopathies and in the preterm infants with respiratory distress. A review and personal findings].
Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Agents; Cerebral Angiography; C | 2005 |
Patent ductus arteriosus: current clinical status.
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Respiratory Dis | 1980 |
Evidence-based neonatology: making a difference beyond discharge from the neonatal nursery.
Topics: Breast Feeding; Cryotherapy; Cyclooxygenase Inhibitors; Evidence-Based Medicine; Extracorporeal Memb | 2002 |
The patent ductus arteriosus.
Topics: Acute Kidney Injury; Animals; Clinical Trials as Topic; Ductus Arteriosus; Ductus Arteriosus, Patent | 1978 |
[Fetal toxicity of non-steroidal anti-inflammatory agents].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Fetal Diseases; Heart Failure; Humans; Indomethacin | 1992 |
The relationship of symptomatic patent ductus arteriosus to respiratory distress in premature newborn infants.
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Ligat | 1987 |
Patent ductus arteriosus in the neonate.
Topics: Alprostadil; Blood Circulation; Clinical Trials as Topic; Digoxin; Ductus Arteriosus; Ductus Arterio | 1986 |
17 trials available for indomethacin and Infantile Respiratory Distress Syndrome
| Article | Year |
|---|---|
Comparison of ibuprofen and indomethacin therapy for patent ductus arteriosus in preterm infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Femal | 2003 |
Early closure of patent ductus arteriosus with indomethacin in preterm infants with idiopathic respiratory distress syndrome.
Topics: Clinical Trials as Topic; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, | 1983 |
Early closure of the patent ductus arteriosus in very low-birth-weight infants: a controlled trial.
Topics: Bronchial Diseases; Clinical Trials as Topic; Ductus Arteriosus, Patent; Humans; Indomethacin; Infan | 1981 |
Indomethacin treatment for symptomatic patent ductus arteriosus: a double-blind control study.
Topics: Clinical Trials as Topic; Double-Blind Method; Ductus Arteriosus, Patent; Gastrointestinal Hemorrhag | 1981 |
Tocolysis in advanced preterm labor: impact on neonatal outcome.
Topics: Cohort Studies; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Magnesiu | 1995 |
Aspirin versus indomethacin treatment of patent ductus arteriosus in preterm infants with respiratory distress syndrome.
Topics: Aspirin; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Logistic Models; Prospect | 1995 |
Effects of early indomethacin administration on oxygenation and surfactant requirement in low birth weight infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biological Products; Double-Blind Method; Ductus Arteriosus | 1997 |
Treatment of patent ductus arteriosus with ibuprofen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Administration Schedule; Ductus Arteriosus, Patent; Ec | 1997 |
A comparison of ibuprofen and indomethacin for closure of patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newbo | 2000 |
Early versus late indomethacin treatment for patent ductus arteriosus in premature infants with respiratory distress syndrome.
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Injec | 2001 |
The patent ductus arteriosus.
Topics: Acute Kidney Injury; Animals; Clinical Trials as Topic; Ductus Arteriosus; Ductus Arteriosus, Patent | 1978 |
Disposition of indomethacin in preterm infants.
Topics: Birth Weight; Ductus Arteriosus, Patent; Gestational Age; Half-Life; Humans; Indomethacin; Infant, L | 1979 |
Symptomatic patent ductus arteriosus following prophylactic indomethacin. A clinical and biochemical appraisal.
Topics: Dinoprostone; Ductus Arteriosus, Patent; Epoprostenol; High-Frequency Ventilation; Humans; Indometha | 1991 |
Ductal patency in neonates with respiratory distress syndrome. A randomized surfactant trial.
Topics: Ductus Arteriosus, Patent; Echocardiography; Gestational Age; Humans; Indomethacin; Infant, Newborn; | 1991 |
Prophylactic treatment of asymptomatic patent ductus arteriosus in premature infants with respiratory distress syndrome.
Topics: Clinical Trials as Topic; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Random A | 1987 |
Patent ductus arteriosus in the neonate.
Topics: Alprostadil; Blood Circulation; Clinical Trials as Topic; Digoxin; Ductus Arteriosus; Ductus Arterio | 1986 |
Failure of prophylactic indomethacin to improve the outcome of the very low birth weight infant.
Topics: Double-Blind Method; Ductus Arteriosus, Patent; Echocardiography; Follow-Up Studies; Humans; Indomet | 1987 |
61 other studies available for indomethacin and Infantile Respiratory Distress Syndrome
| Article | Year |
|---|---|
Hospital variation in medical and surgical treatment of patent ductus arteriosus.
Topics: Birth Weight; California; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Gestational | 2015 |
Effect of obesity on neonatal outcomes in pregnancies with preterm premature rupture of membranes.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Birth Weight; Case-Control Studies; Cerebral Hemorrhage; | 2016 |
Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; Bronchopulmonary Dysplasia | 2008 |
Indomethacin pharmacodynamics are altered by surfactant: a possible challenge to current indomethacin dosing guidelines created before surfactant availability.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Biological Products; Coho | 2010 |
Management of patent ductus arteriosus in term or near-term neonates with respiratory distress.
Topics: Analysis of Variance; Cardiac Surgical Procedures; Cardiotonic Agents; Cardiovascular Agents; Diuret | 2010 |
Comparative evaluation for the use of oral ibuprofen and intravenous indomethacin in Korean infants with patent ductus.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Comorbidity; Ductus Arteriosus, Paten | 2012 |
Recovery of prostaglandin production associated with reopening of the ductus arteriosus after indomethacin treatment in preterm infants with respiratory distress syndrome.
Topics: Child; Child, Preschool; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, P | 1982 |
Neonatal outcome after exposure to indomethacin in utero: a retrospective case cohort study.
Topics: Apgar Score; Betamethasone; Birth Weight; Cesarean Section; Cohort Studies; Female; Fetal Blood; Ges | 2003 |
Indomethacin-induced early patent ductus arteriosus closure cannot be predicted by a decrease in pulse pressure.
Topics: Blood Pressure; Cardiovascular Agents; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Low | 2004 |
Inhaled nitric oxide.
Topics: Administration, Inhalation; Anti-Inflammatory Agents, Non-Steroidal; Bronchopulmonary Dysplasia; Dev | 2005 |
Urinary metabolites of oxidative stress and nitric oxide in preterm and term infants.
Topics: Biomarkers; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Male; Nitrates; Nitric | 2006 |
Risk factors for persistent ductus arteriosus patency during indomethacin treatment.
Topics: Betamethasone; Cohort Studies; Ductus Arteriosus, Patent; Gestational Age; Glucocorticoids; Humans; | 2007 |
RDS prophylaxis in preterm labor: corticosteroids and beta-mimetics association-indications and limits.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adrenal Cortex Hormones; Drug Therapy, Combination; Female; Huma | 1984 |
Urinary excretion rates of 6-keto-PGF1 alpha in preterm infants recovering from respiratory distress with and without patent ductus arteriosus.
Topics: 6-Ketoprostaglandin F1 alpha; Alprostadil; Dinoprost; Dinoprostone; Ductus Arteriosus, Patent; Femal | 1984 |
[Persistent ductus arteriosus in premature infants].
Topics: Ductus Arteriosus; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Prematu | 1983 |
[Indomethacin treatment of persistent ductus arteriosus in premature infants].
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Respi | 1983 |
Indomethacin versus immediate ligation in the treatment of 82 newborns with patent ductus arteriosus.
Topics: Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Ligation; Male; Prognosis; | 1983 |
Respiratory distress syndrome and presence of phosphatidylglycerol: report of three cases.
Topics: Adult; Amniotic Fluid; Animals; Cesarean Section; Female; Humans; Indomethacin; Infant, Newborn; Mal | 1984 |
Prolonged bleeding time in preterm infants receiving indomethacin for patent ductus arteriosus.
Topics: Bleeding Time; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Female; Hemorrhage; Humans; Indometha | 1984 |
[Therapeutic problems with indomethacin in preterm infants with persistent ductus arteriosus].
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Kidne | 1983 |
Congenital heart disease and respiratory distress syndrome. Reversal of indomethacin closure of patent ductus arteriosus by prostaglandin therapy in a preterm infant.
Topics: Alprostadil; Ductus Arteriosus, Patent; Heart Defects, Congenital; Humans; Hypoxia; Indomethacin; In | 1982 |
The contribution of PDA in the neonate with severe RDS.
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Phospholipids; | 1980 |
[Closure of persistent ductus arteriosus in premature infants by drug therapy].
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Inter | 1981 |
Preschool assessment of infants with a patent ductus arteriosus: comparison of ligation and indomethacin therapy.
Topics: Body Height; Body Weight; Bronchopulmonary Dysplasia; Child Development; Child, Preschool; Ductus Ar | 1982 |
Variability of serum indomethacin concentrations after oral and intravenous administration to preterm infants.
Topics: Administration, Oral; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Prem | 1982 |
[Treatment of patent ductus arteriosus in preterm infants].
Topics: Digoxin; Ductus Arteriosus, Patent; Female; Furosemide; Humans; Indomethacin; Infant, Low Birth Weig | 1982 |
[Ductus arteriosus persistens in the newborn with respiratory distress syndrome. Experience with indomethacin and operative ligation].
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Ligation; Respiratory Distress Syn | 1982 |
[An alternative in the management of patent ductus arteriosus using indomethacin in premature newborn infants].
Topics: Birth Weight; Ductus Arteriosus, Patent; Gestational Age; Humans; Indomethacin; Infant, Newborn; Inf | 1982 |
Renal functions and clinical disorders in the neonate.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Asphyxia Neonatorum; Furosemide; Humans; Indomethacin; I | 1981 |
Management of patent ductus arteriosus in preterm babies.
Topics: Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Heart Failure; Humans; Indomethacin; Infant, N | 1980 |
[Persistance of fetal circulation. a case associated to maternal indomethacin administration (author's transl)].
Topics: Female; Hemodynamics; Humans; Indomethacin; Infant, Newborn; Labor, Obstetric; Male; Persistent Feta | 1980 |
[Ductus ligation in idiopathic respiratory distress syndrome of the premature infant].
Topics: Birth Weight; Ductus Arteriosus, Patent; Gestational Age; Humans; Indomethacin; Infant, Newborn; Inf | 1980 |
Patent ductus arteriosus in infants of low birth weight.
Topics: Ductus Arteriosus, Patent; Female; Heart Failure; Humans; Indomethacin; Infant, Low Birth Weight; In | 1980 |
Closure of patent ductus arteriosus decreases pulmonary myeloperoxidase in premature infants with respiratory distress syndrome.
Topics: Birth Weight; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature; I | 1995 |
Developmental changes in renal artery blood flow velocity during the first three weeks of life in preterm neonates.
Topics: Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Abdominal; Blood Flow Velocity | 1996 |
Preterm delivery after indomethacin. A risk factor for neonatal complications?
Topics: Cohort Studies; Ductus Arteriosus, Patent; Enterocolitis, Pseudomembranous; Female; Hemorrhage; Huma | 1996 |
Treatment of patent ductus arteriosus with low-dose indomethacin in very low birth weight neonates with impairment of renal function: report of three cases.
Topics: Adult; Blood Urea Nitrogen; Contraindications; Creatinine; Ductus Arteriosus, Patent; Female; Gestat | 1996 |
The addition of indomethacin to betamimetics for tocolysis: any benefit for the neonate?
Topics: Adrenergic beta-Agonists; Bronchopulmonary Dysplasia; Cohort Studies; Female; Fetal Membranes, Prema | 1998 |
The principles and practice of evidence-based neonatology.
Topics: Adrenal Cortex Hormones; Evidence-Based Medicine; Humans; Indomethacin; Infant, Newborn; Infant, Pre | 1999 |
The contracted type of endocardial fibroelastosis.
Topics: Disease Progression; Ductus Arteriosus, Patent; Echocardiography; Endocardial Fibroelastosis; Fatal | 1999 |
Hemodynamic changes induced by liposomes and liposome-encapsulated hemoglobin in pigs: a model for pseudoallergic cardiopulmonary reactions to liposomes. Role of complement and inhibition by soluble CR1 and anti-C5a antibody.
Topics: Animals; Complement Activation; Complement C5a; Complement System Proteins; Female; Hemodynamics; He | 1999 |
Effect of patent ductus arteriosus and indomethacin treatment on serum cardiac troponin T levels in preterm infants with respiratory distress syndrome.
Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Pre | 2000 |
Effect of maternal tocolysis on the incidence of severe periventricular/intraventricular haemorrhage in very low birthweight infants.
Topics: Anti-Inflammatory Agents; Apgar Score; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; I | 2001 |
Minimal effective dose of indomethacin for the treatment of patent ductus arteriosus in preterm infants.
Topics: Cardiovascular Agents; Dose-Response Relationship, Drug; Ductus Arteriosus, Patent; Echocardiography | 2002 |
Closure of the patent ductus arteriosus with ligation and indomethacin: a consecutive experience.
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Ligation; Respiratory Distress Syn | 1978 |
[Indomethacin in IRDS with PDA phenomenon (author's transl)].
Topics: Apnea; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Respiratory Distress Syndro | 1979 |
Commentary: patent ductus arteriosus and the respiratory distress syndrome--a perspective.
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant; Infant, Newborn; Respiration, Artificial; R | 1977 |
Management of premature labor.
Topics: Aspirin; Bed Rest; Betamethasone; Estrogens; Ethanol; Female; Fetal Membranes, Premature Rupture; Gl | 1978 |
Problem of patent ductus arteriosus in premature infants.
Topics: Animals; Aspirin; Blood Pressure; Coronary Circulation; Ductus Arteriosus, Patent; Heart Failure; He | 1978 |
Failure of indomethacin therapy to induce closure of patent ductus arteriosus in premature infants with respiratory distress syndrome.
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant; Infant, Newborn; Infant, Premature; Respira | 1977 |
Effects of a clinically detectable PDA on pulmonary mechanics measures in VLBW infants with RDS.
Topics: Airway Resistance; Ductus Arteriosus, Patent; Female; Follow-Up Studies; Humans; Indomethacin; Infan | 1991 |
The influence of respiratory distress syndrome on heart rate variability in very preterm infants.
Topics: Age Factors; Birth Weight; Blood Gas Monitoring, Transcutaneous; Cerebral Hemorrhage; Ductus Arterio | 1991 |
Early screening and treatment of "silent" patent ductus arteriosus in prematures with RDS.
Topics: Birth Weight; Ductus Arteriosus, Patent; Echocardiography, Doppler; Female; Humans; Indomethacin; In | 1991 |
Closure of the ductus arteriosus with indomethacin in ventilated neonates with respiratory distress syndrome. Effects of pulmonary compliance and ventilation.
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant; Infant, Newborn; Lung Compliance; Respirati | 1991 |
Effects of dexamethasone and indomethacin on elastase, alpha 1-proteinase inhibitor, and fibronectin in bronchoalveolar lavage fluid from neonates.
Topics: Acute-Phase Proteins; alpha 1-Antitrypsin; Blood Proteins; Bronchoalveolar Lavage Fluid; Bronchopulm | 1988 |
Does the respiratory distress syndrome in twins and singletons run different risks of persistent ductus arteriosus?
Topics: Diseases in Twins; Ductus Arteriosus, Patent; Echocardiography; Humans; Indomethacin; Infant, Low Bi | 1989 |
Early treatment of patent ductus arteriosus in premature infants with severe respiratory distress syndrome.
Topics: Bronchopulmonary Dysplasia; Ductus Arteriosus; Ductus Arteriosus, Patent; Echocardiography; Female; | 1988 |
[New aspects on the pathogenesis of patent ductus arteriosus in premature infants].
Topics: 6-Ketoprostaglandin F1 alpha; Combined Modality Therapy; Dinoprostone; Ductus Arteriosus, Patent; Ep | 1986 |
Obstetric management of the very low birth weight fetus.
Topics: Adrenal Cortex Hormones; Extraction, Obstetrical; Female; Fetal Distress; Fetal Monitoring; Fetal Or | 1986 |
[Indomethacin and furosemide in closure of ductus arteriosus].
Topics: Drug Evaluation; Ductus Arteriosus, Patent; Female; Furosemide; Humans; Indomethacin; Infant, Newbor | 1986 |
Fetal and neonatal effects of indomethacin used as a tocolytic agent.
Topics: Birth Weight; Female; Fetus; Humans; Indomethacin; Infant Mortality; Infant, Newborn; Infant, Newbor | 1985 |