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indomethacin and Infant, Premature, Diseases

indomethacin has been researched along with Infant, Premature, Diseases in 320 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Infant, Premature, Diseases: Diseases that occur in PREMATURE INFANTS.

Research Excerpts

ExcerptRelevanceReference
"Prophylactic indomethacin reduces the risk of severe intraventricular hemorrhage (IVH) but does not reduce death or neurodevelopmental impairment (NDI) among extremely low birth weight (ELBW) infants."9.27Effect of Prophylactic Indomethacin in Extremely Low Birth Weight Infants Based on the Predicted Risk of Severe Intraventricular Hemorrhage. ( Davis, PG; Foglia, EE; Haslam, R; Roberts, RS; Schmidt, B; Stoller, JZ, 2018)
"Postnatal indomethacin is reportedly associated with an increased incidence of necrotizing enterocolitis (NEC) in preterm infants."7.77The risk of necrotizing enterocolitis after indomethacin tocolysis. ( Holzhausen, KA; Kellogg, H; Lulic-Botica, M; Pruder, S; Salari, V; Sood, BG; Thomas, R, 2011)
"Dexamethasone or indomethacin predisposes very low birth weight (VLBW) neonates to spontaneous intestinal perforation (SIP)."7.73Concurrent use of indomethacin and dexamethasone increases the risk of spontaneous intestinal perforation in very low birth weight neonates. ( Friedlich, P; Paquette, L; Ramanathan, R; Seri, I, 2006)
"Sequential bleeding times were performed on 25 preterm infants receiving intravenous indomethacin for closure of the patent ductus arteriosus."7.67Prolonged bleeding time in preterm infants receiving indomethacin for patent ductus arteriosus. ( Bejar, R; Corazza, MS; Cvetnic, W; Davis, RF; Merritt, TA, 1984)
"This is a case report of focal intestinal perforation in a premature neonate following intravenous administration of indomethacin for patent ductus arteriosus."7.67Localized intestinal perforation following intravenous indomethacin in premature infants. ( Leonard, AS; Snover, DC; Wolf, WM, 1989)
"Within 9 months we observed intestinal perforations in three very low birth weight (VLBW) infants undergoing indomethacin treatment for symptomatic patent ductus arteriosus (sPDA)."7.67Intestinal perforation associated with indomethacin treatment in premature infants. ( Bolkenius, M; Kühl, G; Seyberth, HW; Wille, L, 1985)
"Indomethacin has been also used in women with short cervices as well as in those with idiopathic polyhydramnios."5.38Indomethacin in pregnancy: applications and safety. ( Abou-Ghannam, G; Nassar, AH; Usta, IM, 2012)
"The use of indomethacin to treat patent ductus arteriosus in preterm infants may either decrease the incidence of necrotizing enterocolitis by stabilizing or closing the ductus arteriosus or increase its incidence by a direct constricting effect on mesenteric blood vessels."5.33Patent ductus arteriosus, indomethacin and necrotizing enterocolitis in very low birth weight infants: a population-based study. ( Dollberg, S; Lusky, A; Reichman, B, 2005)
"Indomethacin use has been implicated as a co-risk factor for SIP when combined with glucocorticoids, but previous evidence argued against indomethacin being an independent risk factor when used prophylactically."5.33New insights into spontaneous intestinal perforation using a national data set: (1) SIP is associated with early indomethacin exposure. ( Attridge, JT; Clark, R; Gordon, PV; Walker, MW, 2006)
"Prophylactic indomethacin reduces the risk of severe intraventricular hemorrhage (IVH) but does not reduce death or neurodevelopmental impairment (NDI) among extremely low birth weight (ELBW) infants."5.27Effect of Prophylactic Indomethacin in Extremely Low Birth Weight Infants Based on the Predicted Risk of Severe Intraventricular Hemorrhage. ( Davis, PG; Foglia, EE; Haslam, R; Roberts, RS; Schmidt, B; Stoller, JZ, 2018)
" In view of this and with its higher incidence of necrotizing enterocolitis, we do not recommend using prolonged low-dose indomethacin for closing the patent ductus arteriosus in very low birth weight infants."5.10Randomized trial of prolonged low-dose versus conventional-dose indomethacin for treating patent ductus arteriosus in very low birth weight infants. ( Lee, J; Leong, JY; Rajadurai, VS; Tan, KW; Wong, EH; Wong, KY, 2003)
"Ibuprofen therapy on the third day of life is as efficacious as indomethacin for the treatment of patent ductus arteriosus in preterm infants with the respiratory distress syndrome and is significantly less likely to induce oliguria."5.09A comparison of ibuprofen and indomethacin for closure of patent ductus arteriosus. ( Degroote, K; Langhendries, JP; Lecoutere, D; Smets, K; Van de Broek, H; Van Overmeire, B; Weyler, J, 2000)
"This historical cohort study included 45 infants born with birth weights of 1250 g or less and received indomethacin in the first 12 hours of life for intraventricular hemorrhage prevention."5.09The use of indomethacin for the prevention of intraventricular brain hemorrhage in high-risk neonates. ( Al-Alaiyan, SA; Al-Shawaf, EM; Aqeel, AY; Gamal, MH, 2000)
"Ninety infants, with birth weights of 600 to 1250 gm, were entered into a prospective, randomized, controlled trial to receive either indomethacin, 0."5.08Prophylactic indomethacin therapy in the first twenty-four hours of life for the prevention of patent ductus arteriosus in preterm infants treated prophylactically with surfactant in the delivery room. ( Cabalka, AK; Couser, RJ; Ferrara, TB; Hoekstra, RE; Payne, NR; Schilling, CG; Wright, GB, 1996)
"In a randomized study the effect of an early prophylactic indomethacin treatment on the incidence of the patent ductus arteriosus (PDA) in very low birth weight infants (VLBWI) and their postnatal course were investigated."5.06[Effects of early therapy with indomethacin on the manifestation of a persistent ductus arteriosus in extremely underweight premature infants]. ( Böttcher, H; Grubbe, G; Ockert, C; Ruckhäberle, KE; Vogtmann, C, 1988)
"The impact of early prophylactic use of intravenous indomethacin on the incidence and severity of periventricular-intraventricular hemorrhage and patent ductus arteriosus in 199 oxygen-requiring premature infants (less than or equal to 1300 g birth weight) was prospectively investigated."5.06Prophylactic indomethacin for prevention of intraventricular hemorrhage in premature infants. ( Bancalari, E; Bandstra, ES; Ferrer, PL; Flynn, J; Goldberg, RN; Gregorios, JB; Montalvo, BM; Pacheco, I, 1988)
"Antenatal indomethacin may be associated with an increased risk of periventricular leukomalacia and necrotizing enterocolitis in premature infants and therefore should be used judiciously for tocolysis."4.84Metaanalysis of the effect of antenatal indomethacin on neonatal outcomes. ( Amin, SB; Glantz, JC; Sinkin, RA, 2007)
"Three preterm infants exposed antenatally to indomethacin developed a characteristic syndrome consisting of edema and hydrops with a bleeding disorder at birth, oliguric renal failure during the first 3 postnatal days, and acute pneumoperitoneum resulting from localized ileal perforation(s) at the end of the first week of life."4.77Oligohydramnios, renal insufficiency, and ileal perforation in preterm infants after intrauterine exposure to indomethacin. ( Coppens, M; Cuvelier, C; de Praeter, C; Dhont, M; Govaert, P; Leroy, JG; Thiery, M; Vanhaesebrouck, P, 1988)
"To compare the incidence of medical closure of patent ductus arteriosus (PDA) and adverse events (acute renal dysfunction, necrotizing enterocolitis, spontaneous intestinal perforation, and gastrointestinal bleeding) between preterm infants who received indomethacin and ibuprofen for the treatment of PDA."3.79Effectiveness and safety of indomethacin versus ibuprofen for the treatment of patent ductus arteriosus in preterm infants. ( Bali, V; Harabor, A; Kamaluddeen, M; Sivanandan, S; Soraisham, AS, 2013)
"Postnatal indomethacin is reportedly associated with an increased incidence of necrotizing enterocolitis (NEC) in preterm infants."3.77The risk of necrotizing enterocolitis after indomethacin tocolysis. ( Holzhausen, KA; Kellogg, H; Lulic-Botica, M; Pruder, S; Salari, V; Sood, BG; Thomas, R, 2011)
" neonatologists reported that they would ligate a PDA when infants with birth weights <900 g required mechanical ventilation (and indomethacin was contraindicated or had failed to close the PDA), U."3.76Feeding practices and patent ductus arteriosus ligation preferences-are they related? ( Clyman, RI; Jhaveri, N; Soll, RF, 2010)
"There were no statistically significant differences between the two protocol groups when comparing percentages of neonates with gestational age≤28 weeks, birth weight≤1000 g, male gender or receiving indomethacin for the indication of PDA prophylaxis vs."3.76Comparison of two neonatal indomethacin protocols: efficacy and outcome for patent ductus arteriosus closure. ( Chorne, N; Rosito, G; Sum, K, 2010)
"Our objective was to determine the effect of chorioamnionitis on plasma prostaglandin E2 (PGE2) and thromboxane B2 (TxB2) during the first week in preterm infants."3.74Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants. ( Aranda, JV; Glibetic, M; Natarajan, G; Thomas, RL, 2008)
"Diet, indomethacin, and early use of dexamethasone have been implicated as possible causes of necrotizing enterocolitis and intestinal perforation."3.74Prevention of necrotizing enterocolitis in preterm infants: a 20-year experience. ( Achanti, B; Lilien, L; Mehta, SK; Pietz, J; Stepka, EC, 2007)
"Dexamethasone or indomethacin predisposes very low birth weight (VLBW) neonates to spontaneous intestinal perforation (SIP)."3.73Concurrent use of indomethacin and dexamethasone increases the risk of spontaneous intestinal perforation in very low birth weight neonates. ( Friedlich, P; Paquette, L; Ramanathan, R; Seri, I, 2006)
"Preterm infants with exposure to antenatal indomethacin might be at increased risk of grade I and II intraventricular haemorrhage and those with both ante- and postnatal exposure at an increased risk of necrotising enterocolitis and sepsis."3.70Perinatal indomethacin treatment and neonatal complications in preterm infants. ( Ikonen, S; Ojala, R; Tammela, O, 2000)
"Sequential bleeding times were performed on 25 preterm infants receiving intravenous indomethacin for closure of the patent ductus arteriosus."3.67Prolonged bleeding time in preterm infants receiving indomethacin for patent ductus arteriosus. ( Bejar, R; Corazza, MS; Cvetnic, W; Davis, RF; Merritt, TA, 1984)
"This is a case report of focal intestinal perforation in a premature neonate following intravenous administration of indomethacin for patent ductus arteriosus."3.67Localized intestinal perforation following intravenous indomethacin in premature infants. ( Leonard, AS; Snover, DC; Wolf, WM, 1989)
"Within 9 months we observed intestinal perforations in three very low birth weight (VLBW) infants undergoing indomethacin treatment for symptomatic patent ductus arteriosus (sPDA)."3.67Intestinal perforation associated with indomethacin treatment in premature infants. ( Bolkenius, M; Kühl, G; Seyberth, HW; Wille, L, 1985)
" Intravenous indomethacin was administered to 67 infants with successful closure in 91% of the patients and in 83% of those with birth weights less than 1,000 g."3.66Parenteral indomethacin for closure of the patent ductus arteriosus. Clinical experience with 67 preterm infants. ( Alexson, CG; Harris, JP; Longfield, L; Manning, JA; Merritt, TA, 1982)
" Four had severe hyaline membrane disease and one had chronic bronchopulmonary dysplasia; all received furosemide."3.66Urinary excretion of prostaglandin E following the administration of furosemide and indomethacin to sick low-birth-weight infants. ( Demers, LM; Friedman, Z; Maisels, MJ; Marks, KH; Uhrmann, S, 1978)
"Failure of closure of the patent ductus arteriosus (PDA) may be associated with harm."2.79A randomised placebo-controlled trial of early treatment of the patent ductus arteriosus. ( Evans, N; Gill, A; Jeffery, M; Kluckow, M, 2014)
"A significant patent ductus arteriosus (PDA) is a common finding in the first days of life and, if persistent, is associated with an increased morbidity and mortality in the preterm newborn."2.75Effect of indomethacin infused over 30 minutes on cerebral fractional tissue oxygen extraction in preterm newborns with a patent ductus arteriosus. ( Bos, AF; Keating, P; ter Horst, H; van Hoften, J; Verhagen, E, 2010)
"Indomethacin dosing was withheld in the BNP-guided group if the 12 or 24 h BNP concentrations were found to be <100 pg/ml."2.74B-type natriuretic peptide concentrations to guide treatment of patent ductus arteriosus. ( Attridge, JT; Kaufman, DA; Lim, DS, 2009)
"Ibuprofen has the same efficiency as indomethacin for the treatment of symptomatic patent ductus arteriosus in preterm infants and less likely to induce necrotizing enterocolitis and renal toxicity than indomethacin."2.71A comparison of oral ibuprofen and intravenous indomethacin for closure of patent ductus arteriosus in preterm infants. ( Chotigeat, U; Jirapapa, K; Layangkool, T, 2003)
"Ibuprofen has recently been shown to be effective in closing PDA with fewer hemodynamic effects."2.71[Ibuprofen versus indomethacin in the treatment of patent ductus arteriosus in preterm infants]. ( Cano Sánchez, A; Carrasco Moreno, JI; Fernández Gilino, C; Gimeno Navarro, A; Gutiérrez Laso, A; Izquierdo Macián, I; Morcillo Sopena, F, 2005)
"To evaluate whether a prolonged low-dose course of indomethacin would produce an improved closure rate and have fewer side effects compared with a short standard dosage schedule in the management of patent ductus arteriosus (PDA) in preterm infants."2.69Short versus prolonged indomethacin therapy for patent ductus arteriosus in preterm infants. ( Iivainen, T; Ikonen, S; Janas, M; Koivisto, M; Lautamatti, V; Ojala, R; Pokela, ML; Tammela, O, 1999)
" One group received 3 doses of intravenous indomethacin at the dosage of 0."2.69Indomethacin prophylaxis for patent ductus arteriosus (PDA) in infants with a birth weight of less than 1250 grams. ( Khowsathit, P; Patchakapati, B; Supapannachart, S, 1999)
"Tocolysis in advanced preterm labor delays delivery by more than 48 hours in 50% of patients."2.68Tocolysis in advanced preterm labor: impact on neonatal outcome. ( Barke, JI; de Veciana, M; Major, CA; Porto, M, 1995)
"Fourteen preterm infants with patent ductus arteriosus were studied during three subsequent indomethacin bolus administrations with intervals of 12 and 24 h."2.67Effects of repeated indomethacin administration on cerebral oxygenation and haemodynamics in preterm infants: combined near infrared spectrophotometry and Doppler ultrasound study. ( Hopman, JC; Kollée, LA; Liem, KD; Oeseburg, B, 1994)
"Four indomethacin-treated and three saline solution-treated infants had parenchymal extension of the hemorrhage."2.67Low-dose indomethacin therapy and extension of intraventricular hemorrhage: a multicenter randomized trial. ( Allan, W; Ehrenkranz, RA; Katz, KH; Makuch, RW; Ment, LR; Oh, W; Phillip, AG; Schneider, KC; Taylor, KJ; Vohr, B, 1994)
"This study examined the response of the patent ductus arteriosus (PDA) to intravenous Indomethacin using serial two dimensional and Doppler echocardiography and documented the complications associated with therapy."2.67Intravenous indomethacin therapy in preterm neonates with patent ductus arteriosus. ( Rajadurai, VS; Yu, VY, 1991)
"Over a 4-year period, 63 premature babies presenting with patent ductus arteriosus were treated with indomethacin at two different dosage levels (0."2.66[Treatment of patent ductus arteriosus in premature infants by indomethacin]. ( Bianchetti, G; Marchal, F; Monin, P; Morselli, P; Vert, P, 1987)
"Treatment with indomethacin prolonged bleeding time, raised serum creatinine concentrations, and was associated with gastrointestinal haemorrhage in seven infants."2.66Early administration of indomethacin to preterm infants. ( Cooke, RW; Doyle, J; Rennie, JM, 1986)
"The indomethacin-treated group had significant decreases in serum prostaglandin values 30 hours after the initiation of therapy."2.66Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants. ( Duncan, CC; Ehrenkranz, RA; Gettner, P; Kleinman, CS; Ment, LR; Pitt, BR; Scott, DT; Stewart, WB; Taylor, KJ, 1985)
"The 75% patent ductus arteriosus closure rate with indomethacin treatment in phase 1 was not statistically significant due to a 44% spontaneous closure rate in the control group."2.65Indomethacin treatment for symptomatic patent ductus arteriosus: a double-blind control study. ( Aziz, KU; Hunt, CE; Newfeld, EA; Wilson, A; Yanagi, RM, 1981)
"The pathophysiology leading to preterm labor is not well understood and often multifactorial; initiating factors include intrauterine infection, inflammation, ischemia, overdistension, and hemorrhage."2.48Tocolytic therapy for acute preterm labor. ( Abramovici, A; Cantu, J; Jenkins, SM, 2012)
"Although ongoing patency of the ductus arteriosus is common in small extremely preterm infants, consensus is lacking regarding its clinical significance and treatment strategies."2.48The ductus arteriosus: a refined approach! ( McNamara, PJ; Sehgal, A, 2012)
"Although a moderate-sized patent ductus arteriosus (PDA) needs to be closed by the time a child is 1-2 years old, there is great uncertainty about whether it needs to be closed during the neonatal period."2.48Patent ductus arteriosus: are current neonatal treatment options better or worse than no treatment at all? ( Clyman, RI; Couto, J; Murphy, GM, 2012)
""Patent ductus arteriosus is one of most common problems that physicians caring for preterm infants have to face."2.47Patent ductus arteriosus: wait and see? ( Ciarmoli, E; Mosca, F; Schena, F, 2011)
"Persistent patent ductus arteriosus (PDA) is associated with mortality and morbidity in preterm infants."2.46Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants. ( Davis, PG; Fowlie, PW; McGuire, W, 2010)
"Indomethacin has long been the drug of choice."2.45Therapeutic closure of the ductus arteriosus: benefits and limitations. ( Boubred, F; Mercanti, I; Simeoni, U, 2009)
"Indomethacin is a prostaglandin inhibitor used to treat patent ductus arteriosus (PDA) in preterm infants."2.44Prolonged versus short course of indomethacin for the treatment of patent ductus arteriosus in preterm infants. ( Davis, P; Herrera, C; Holberton, J, 2007)
" The drug has prolonged elimination (plasma half-life = ca 23 hours), suggesting that once daily dosing is appropriate."2.43Systematic review: intravenous Ibuprofen in preterm newborns. ( Aranda, JV; Thomas, R, 2006)
"Indomethacin is a prostaglandin inhibitor used to treat patent ductus arteriosus (PDA) in preterm infants."2.42Prolonged versus short course of indomethacin for the treatment of patent ductus arteriosus in preterm infants. ( Davis, P; Herrera, C; Holberton, J, 2004)
"Indomethacin has been used successfully to treat symptomatic PDA and may also prevent or limit IVH in the neonatal period."2.41Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants. ( Davis, PG; Fowlie, PW, 2002)
"Indomethacin is used to treat symptomatic patent ductus arteriosus and may prevent or limit intraventricular haemorrhage in the neonatal period."2.41Intravenous indomethacin for preventing mortality and morbidity in very low birth weight infants. ( Fowlie, PW, 2000)
"Indomethacin was used for median (IQR) 3 (2-5) days while ibuprofen was given for 3 (2-4) days, at a median of 8 and 10 days after birth, respectively; surgical treatment was used later at 33 (24-45) days after birth."1.72Management of patent ductus arteriosus in very preterm infants in England and Wales: a retrospective cohort study. ( Al-Turkait, A; Choonara, I; Ojha, S; Szatkowski, L, 2022)
"Few studies exist that have evaluated the effects of indomethacin dosing frequency as a factor associated with successful patent ductus arteriosus closure in very low birth weight neonates."1.51Indomethacin dosing strategy and neonatal patent ductus arteriosus closure. ( Messina, C; Mintzer, JP; Rathi, P, 2019)
"Indomethacin has vasoactive properties in cerebral and systemic vascular beds, and it improves cerebral autoregulatory ability."1.39Tocolytic indomethacin: effects on neonatal haemodynamics and cerebral autoregulation in the preterm newborn. ( Baerts, W; Derks, JB; Lemmers, PM; Thewissen, L; van Bel, F, 2013)
"Indomethacin prophylaxis was given at <6 hours of life in 730 infants and at >6 hours of life to 168 infants."1.39Indomethacin prophylaxis to prevent intraventricular hemorrhage: association between incidence and timing of drug administration. ( Laptook, A; Mirza, H; Oh, W; Stonestreet, BS; Tucker, R; Vohr, B, 2013)
"Reports of Bartter syndrome in premature neonates are rare."1.39Bartter syndrome: presentation in an extremely premature neonate. ( Calhoun, DA; Flores, FX; Ojeda, FJ, 2013)
"Indomethacin has been also used in women with short cervices as well as in those with idiopathic polyhydramnios."1.38Indomethacin in pregnancy: applications and safety. ( Abou-Ghannam, G; Nassar, AH; Usta, IM, 2012)
"Multiple indomethacin courses using the standard dosing approach result in high PDA closure rates for infants < 29 weeks gestation."1.38Patent ductus arteriosus in infants <29 weeks gestation--outcomes and factors affecting closure. ( Kapoor, V; Popat, H; Travadi, J, 2012)
"The effect of patent ductus arteriosus (PDA) treatment with cyclooxygenase (COX) inhibitors (indomethacin [INDO] and ibuprofen [IBU]) on regional oxygenation requires further clarification."1.38Does treatment of patent ductus arteriosus with cyclooxygenase inhibitors affect neonatal regional tissue oxygenation? ( Bhatt, M; Mehta, R; Petrova, A, 2012)
"In ibuprofen group, there was no correlation of AQP2 level with urinary osmolality."1.37Urinary aquaporin-2 excretion during ibuprofen or indomethacin treatment in preterm infants with patent ductus arteriosus. ( Aperia, A; Casper, C; Li, Y; Marcoux, MO; Plat-Willson, G; Zelenina, M, 2011)
"Neonatal Bartter syndrome is a rare condition, usually revealed by alkalosis and hypokalemia."1.35[Neonatal Bartter syndrome's special features in very premature newborns]. ( André, JL; Feldmann, M; Hamon, I; Hascoët, JM; Vieux, R, 2009)
"Optimal time to surgical ligation of patent ductus arteriosus (PDA) in very-low-birth-weight (< 1500 g) premature infants remains an area of controversy."1.35Early or late surgical ligation of medical refractory patent ductus arteriosus in premature infants. ( Chang, WC; Hsiao, CC; Tsao, LY; Wung, JT, 2009)
"The use of indomethacin to treat patent ductus arteriosus in preterm infants may either decrease the incidence of necrotizing enterocolitis by stabilizing or closing the ductus arteriosus or increase its incidence by a direct constricting effect on mesenteric blood vessels."1.33Patent ductus arteriosus, indomethacin and necrotizing enterocolitis in very low birth weight infants: a population-based study. ( Dollberg, S; Lusky, A; Reichman, B, 2005)
"Surgical ligation of patent ductus arteriosus (PDA) is widely practised in preterm infants despite no clear evidence that this improves outcomes."1.33Is surgical ligation of patent ductus arteriosus necessary? The Western Australian experience of conservative management. ( Brooks, JM; Doherty, DA; Patole, SK; Simmer, K; Travadi, JN, 2005)
"Ibuprofen treatment caused a significant decrease in urinary AVP (UAVP/Ucr 24."1.33Urinary ET-1, AVP and sodium in premature infants treated with indomethacin and ibuprofen for patent ductus arteriosus. ( Faggian, D; Favaro, F; Lago, P; Plebani, M; Trevisanuto, D; Vedovato, S; Zanardo, V, 2005)
"Indomethacin use has been implicated as a co-risk factor for SIP when combined with glucocorticoids, but previous evidence argued against indomethacin being an independent risk factor when used prophylactically."1.33New insights into spontaneous intestinal perforation using a national data set: (1) SIP is associated with early indomethacin exposure. ( Attridge, JT; Clark, R; Gordon, PV; Walker, MW, 2006)
"Symptomatic patent ductus arteriosus (sPDA) is a common problem in premature infants and can be treated effectively with intravenous indomethacin, leading to permanent ductal closure in 70% to 80% of infants."1.33Effectiveness and side effects of an escalating, stepwise approach to indomethacin treatment for symptomatic patent ductus arteriosus in premature infants below 33 weeks of gestation. ( Beedgen, B; Brüssau, J; Feneberg, R; Huppertz, C; Linderkamp, O; Pöschl, J; Sperandio, M, 2005)
"The patent ductus arteriosus was confirmed by echocardiography."1.31[Dopplersonographic findings in neonates with significant persistent ductus arteriosus]. ( Knüpfer, M; Pulzer, F; Robel-Tillig, E; Vogtmann, C, 2002)
"Persistent patent ductus arteriosus was more common in those infants delivered within 48 hours of maternal indomethacin exposure (40% versus 20% (p<0."1.30Antenatal indomethacin--adverse fetal effects confirmed. ( Baxendale, H; Harding, J; McCowan, L; McLeay, E; O'Donnell, C; Souter, D, 1998)
"Indomethacin treatment was successful in 27 infants."1.30Surgical ligation of patent ductus arteriosus in very low birth weight infants: is it safe? ( Atkinson, JB; Bustorff-Silva, JM; Fonkalsrud, EW; Perez, CA; Villasenor, E, 1998)
"Indomethacin tocolysis has been reported to increase the incidence of persistent PDA in premature infants."1.30Indomethacin tocolysis increases postnatal patent ductus arteriosus severity. ( Eidelman, AI; Ferber, B; Glaser, J; Hammerman, C; Kaplan, M; Schimmel, MS, 1998)
"9 percent, P = 0."1.29Neonatal complications after the administration of indomethacin for preterm labor. ( Clyman, RI; Cooper, BA; Kuller, JA; Merrill, J; Norton, ME, 1993)
"Indomethacin was directly associated with intestinal perforation in 3 patients, and acute renal failure in 1; all 4 died."1.29Optimal management of patent ductus arteriosus in the neonate weighing less than 800 g. ( Langer, JC; Lau, GY; Pipe, S; Shah, J; Trus, T; Winthrop, AL, 1993)
"The indomethacin was prepared by diluting the content of the commercially available 25-mg indomethacin capsule with lactose by the method of trituration."1.28Preterm infants with patent ductus arteriosus: treatment with an enteral preparation of indomethacin. ( Fok, TF; Ho, JK; So, LY; Sung, RY, 1992)
"In 18 infants the patent ductus arteriosus closed after one course of indomethacin; atrial natriuretic peptide levels decreased from median 1240 pg/ml (range 201-5483 pg/ml) to 266 pg/ml (range 62-1108 pg/ml)."1.28Atrial natriuretic peptide in the diagnosis of patent ductus arteriosus. ( Carter, N; Hamilton, PA; Littleton, P; Smith, A; Weir, FJ, 1992)
"Indomethacin infusion was associated with a significant reduction in time averaged mean velocity (TAMV), peak systolic velocity (PSV), and end diastolic velocity in both the anterior cerebral artery and middle cerebral artery."1.28Regional cerebral blood flow velocity changes after indomethacin infusion in preterm infants. ( Austin, NC; Hall, MA; Hames, TK; Pairaudeau, PW, 1992)
" We recommend the use of MA for closure of symptomatic PDA in preterms, especially in those cases where indomethacin is not tolerated or when minute titration of its dosage is impracticable."1.28Therapy of symptomatic patent ductus arteriosus in preterms using mefenemic acid and indomethacin. ( Merchant, RH; Sakhalkar, VS, 1992)
"Indomethacin was given as part of tocolytic management to mothers with a high incidence of early rupture of membranes and preterm labour; and 76 fetuses were exposed to the drug as a result."1.28Cerebral lesions in preterm infants after tocolytic indomethacin. ( Baerts, W; Fetter, WP; Hop, WC; Sauer, PJ; Spritzer, R; Wallenburg, HC, 1990)
"We present pharmacokinetic data of prolonged, intra-arterial indomethacin treatment (i."1.28Pharmacokinetics of intra-arterial indomethacin treatment for patent ductus arteriosus. ( Pollak, A; Salzer, HR; Salzer-Muhar, U; Vergesslich, KA; Weninger, M, 1989)
"The incidence and evolution of patent ductus arteriosus (PDA) was evaluated in twins and preterm singletons with birth weight less than or equal to 1750 g admitted to our Department in 1987 for respiratory distress syndrome (RDS)."1.28Does the respiratory distress syndrome in twins and singletons run different risks of persistent ductus arteriosus? ( Foti, P; Milanesi, O; Stellin, G; Trevisanuto, D; Zambon, P; Zanardo, V, 1989)
"A haemodynamically significant, patent ductus arteriosus in mechanically ventilated preterm infants can be closed by two means today, either medical or surgical."1.28[Indomethacin or ligation in the treatment of persistent ductus arteriosus: a report of clinical experiences]. ( Fürnkranz, H; Sterniste, W, 1989)
"A case of early onset Bartter's syndrome associated with hydramnios, prematurity, hypercalciuria and nephrocalcinosis is reported."1.27A variant of Bartter's syndrome. Bartter's syndrome associated with hydramnios, prematurity, hypercalciuria and nephrocalcinosis. ( Akhtar, M; Cumming, W; Ohlsson, A; Serenius, F; Sieck, U, 1984)
"The necessity of an early closure of a patent ductus arteriosus is now admitted in the very premature infant, but the use of indomethacin in the first days of life is often impossible because of its side-effects."1.27[Surgical ligation of patent ductus arteriosus in the very-low-birth-weight premature infant]. ( Couturier, C; Estève, C; Laguenie, G; Murat, I; Saint-Maurice, JP, 1983)
"Infants who experienced a recurrence of symptomatic PDA had lower birth weights and had received indomethacin at an earlier postnatal age than did infants with a sustained effect."1.27Recurrence of symptomatic patent ductus arteriosus in extremely premature infants, treated with indomethacin. ( Cotton, RB; Graham, TP; Leheup, B; Lindstrom, DP; Mellander, M; Palme, C; Stahlman, MT, 1984)
" The margin between closure of the ductus arteriosus and the deterioration of kidney function in preterm infants treated with a presently recommended indomethacin dosage is too narrow."1.27[Therapeutic problems with indomethacin in preterm infants with persistent ductus arteriosus]. ( Müller, H; Plückthun, H; Seyberth, HW; Ulmer, HE; Wille, L; Wolf, D, 1983)
"Appropriate management of preterm labor mandates early recognition of subtle signs and symptoms; successful therapy is dependent on this issue."1.27Preterm labor: its diagnosis and management. ( Creasy, RK; Gonik, B, 1986)
"Indomethacin treatment for 1 week monitored by drug level determinations was evaluated in 32 preterm infants with symptomatic patent ductus arteriosus (sPDA)."1.27Prolonged indomethacin treatment in preterm infants with symptomatic patent ductus arteriosus: efficacy, drug level monitoring, and patient selection. ( Isken, V; Kühl, PG; Leonhardt, A; Seyberth, HW, 1987)
" Patients with this renal disorder require a permanent high dosed indomethacin therapy."1.27[The significance of renal prostaglandins for kidney function in early childhood]. ( Seyberth, HW, 1987)
"Indomethacin was infused intravenously in five infants."1.27The effect of indomethacin on cerebral blood-flow velocity in premature infants. ( Archer, LN; Evans, DH; Levene, MI, 1987)
"Issues of the pharmacologic therapy of preterm labor, enhancement of lung maturity, and management of labor and delivery are discussed."1.27Obstetric management of the very low birth weight fetus. ( Hayashi, RH; Marshall, CL, 1986)
" Qualitative and quantitative differences in pharmacokinetics and pharmacodynamics of drugs should be considered before dosage regimens can be established."1.27[Peculiarities of drug therapy in childhood]. ( Kusenbach, G; Reinhardt, D, 1986)
"Indomethacin was given by suppository to 18 neonates for the treatment of patent ductus arteriosus."1.27Indomethacin therapy of patent ductus in preterm infants controlled by plasma levels. ( Harvey, DP; Lewis, IG; Maxwell, GM, 1985)
" The mean half-life of elimination (20."1.26Pharmacokinetics of intravenously administered indomethacin in premature infants. ( Carr, I; Luken, JA; Pildes, RS; Raval, D; Thalji, AA; Yeh, TF, 1980)
"Indomethacin was administered from the 20th to the 34th week of gestation to 51 women (59 fetuses) in whom bed rest and a beta-mimetic compound (ritodrine) had failed to stop preterm labor."1.26Perinatal hazards of chronic antenatal tocolysis with indomethacin. ( Baele, G; Derom, R; Thiery, M; Van Egmond, H; Van Kets, H, 1979)
"Indomethacin constricts the patent ductus arteriosus in approximately 70% of premature infants, but temporarily inhibits synthesis of all prostaglandins."1.26Operation or indomethacin for the premature ductus. ( Edmunds, LH, 1978)

Research

Studies (320)

TimeframeStudies, this research(%)All Research%
pre-1990122 (38.13)18.7374
1990's54 (16.88)18.2507
2000's83 (25.94)29.6817
2010's57 (17.81)24.3611
2020's4 (1.25)2.80

Authors

AuthorsStudies
Miller, CJ1
Prusakov, P1
Magers, J1
Speaks, S1
Sacic, H1
Escobar, K1
Abdel-Rasoul, M1
Nelin, LD1
Cambonie, G1
Rozé, JC1
Marchand-Martin, L1
Marret, S1
Durrmeyer, X1
Torchin, H1
Ancel, PY1
Al-Turkait, A1
Szatkowski, L1
Choonara, I1
Ojha, S1
Yao, SL1
Smit, E1
Odd, D1
Rathi, P1
Messina, C1
Mintzer, JP1
Foglia, EE1
Roberts, RS4
Stoller, JZ1
Davis, PG4
Haslam, R1
Schmidt, B5
Lewis, T1
Van Haandel, L1
Scott, A1
Leeder, JS1
Kaur, S1
Stritzke, A1
Soraisham, AS2
Lei, C1
Liu, H1
Wang, H1
Liu, C1
Kemmochi, M1
Senzaki, H1
Miyaji, K1
Hashimoto, M1
Yamaguchi, A1
Ooka, M1
Yokozeki, Y1
Ishii, M1
Sallmon, H1
Aydin, T1
Hort, S1
Kubinski, A1
Bode, C1
Klippstein, T1
Endesfelder, S1
Bührer, C1
Koehne, P1
Chiba, H1
Masutani, S1
Toyoshima, K1
Mori, R1
Baerts, W2
van Bel, F1
Thewissen, L1
Derks, JB1
Lemmers, PM1
Mirza, H1
Oh, W7
Laptook, A2
Vohr, B6
Tucker, R2
Stonestreet, BS2
Flores, FX1
Ojeda, FJ1
Calhoun, DA1
Saida, K1
Nakamura, T1
Hiroma, T1
Takigiku, K1
Yasukochi, S1
Kluckow, M2
Jeffery, M1
Gill, A1
Evans, N3
Nagasawa, H1
Terazawa, D1
Kohno, Y1
Yamamoto, Y1
Kondo, M1
Sugawara, M1
Koyama, T1
Miura, R1
Coceani, F3
ElHassan, NO1
Bird, TM1
King, AJ1
Ambadwar, PB1
Jaquiss, RD1
Kaiser, JR1
Robbins, JM1
Chhina, AS1
Sharma, BK1
Raja, M1
Singhal, M1
Shenoi, A1
Tu, YF1
Wang, LW1
Wang, ST1
Yeh, TF11
Huang, CC1
Vettukattil, JJ1
Samuel, BP1
Stuive, AJ1
Eding, DM1
Haw, MP1
Talavera, MM1
Bixler, G1
Cozzi, C1
Dail, J1
Miller, RR1
McClead, R1
Reber, K1
Kalani, M1
Shariat, M1
Khalesi, N1
Farahani, Z1
Ahmadi, S1
Zanardo, V4
Vedovato, S2
Chiozza, L1
Faggian, D2
Favaro, F2
Trevisanuto, D4
Giardini, A1
Derrick, G1
Natarajan, G1
Glibetic, M1
Thomas, RL1
Aranda, JV4
Busalt, M1
Attridge, JT3
Kaufman, DA1
Lim, DS1
Vieux, R1
Hamon, I1
Feldmann, M1
André, JL1
Hascoët, JM1
Gordon, PV2
Golombek, SG1
Sola, A1
Baquero, H1
Borbonet, D1
Cabañas, F1
Fajardo, C1
Goldsmit, G1
Lemus, L1
Miura, E1
Pellicer, A1
Pérez, JM1
Rogido, M1
Zambosco, G1
van Overmeire, B3
Hsiao, CC1
Wung, JT1
Tsao, LY1
Chang, WC1
Luu, TM2
Ment, LR10
Schneider, KC6
Katz, KH7
Allan, WC4
Vohr, BR3
Carmo, KB1
Paradisis, M1
Noori, S1
Seri, I3
Mercanti, I1
Boubred, F1
Simeoni, U2
Beharry, KD1
Valencia, GB1
Benitz, WE1
Jhaveri, N1
Soll, RF2
Clyman, RI14
Chen, S1
Tacy, T1
Clyman, R1
Keating, P1
Verhagen, E1
van Hoften, J1
ter Horst, H1
Bos, AF1
Katayama, Y1
Minami, H1
Enomoto, M1
Takano, T1
Hayashi, S1
Lee, YK1
Sehgal, A2
Bajaj, R1
Narasimhan, R1
Fowlie, PW5
McGuire, W2
Rosito, G1
Sum, K1
Chorne, N1
Jones, LJ1
Craven, PD1
Attia, J1
Thakkinstian, A1
Wright, I1
Li, Y1
Zelenina, M1
Plat-Willson, G1
Marcoux, MO1
Aperia, A1
Casper, C1
DeMauro, SB1
Brissaud, O1
Guichoux, J1
Sood, BG1
Lulic-Botica, M1
Holzhausen, KA1
Pruder, S1
Kellogg, H1
Salari, V1
Thomas, R2
Seshia, M1
Shankaran, S2
Mildenhall, L1
Tyson, J1
Lui, K1
Fok, T1
Roberts, R1
Abou-Ghannam, G1
Usta, IM1
Nassar, AH1
Schena, F1
Ciarmoli, E1
Mosca, F2
Dani, C1
Fanos, V1
Pusceddu, M1
Dessì, A1
Marcialis, MA1
Garner, RS1
Miller, C1
Burchfield, DJ1
Adrouche-Amrani, L1
Green, RS1
Gluck, KM1
Lin, J1
Popat, H1
Kapoor, V1
Travadi, J1
Maruyama, K1
Fujiu, T1
Abramovici, A1
Cantu, J1
Jenkins, SM1
McNamara, PJ1
Hammerman, C6
Bin-Nun, A1
Kaplan, M3
Couto, J1
Murphy, GM1
Bhatt, M1
Petrova, A1
Mehta, R1
Wadhawan, R1
Saha, S1
Das, A1
Bell, EF1
Stoll, BJ1
Walsh, MC1
Higgins, R1
Wickremasinghe, AC1
Rogers, EE1
Piecuch, RE1
Johnson, BC1
Golden, S1
Moon-Grady, AJ1
Davis, JS1
Ryan, ML1
Shields, JM1
Sola, JE1
Perez, EA1
Neville, HL1
Rodriguez, MM1
Knott, EM1
Zamora, A1
Cavett, C1
Wattsman, TA1
Zhang, CC1
Cheng, GQ1
Sivanandan, S1
Bali, V1
Harabor, A1
Kamaluddeen, M1
Wright, LL1
Davis, P3
Solimano, A1
Supapannachart, S2
Limrungsikul, A1
Khowsathit, P2
Allan, W3
Westerveld, M4
Duncan, CC6
Makuch, RW6
Morley, GM1
Asztalos, EV1
Robertson, CM1
Sauve, RS1
Whitfield, MF1
Lee, J2
Rajadurai, VS2
Tan, KW1
Wong, KY1
Wong, EH1
Leong, JY1
Keller, RL2
Itabashi, K1
Ohno, T1
Nishida, H1
Bellander, M1
Ley, D1
Polberger, S1
Hellström-Westas, L1
Osborn, DA1
Su, PH1
Chen, JY1
Su, CM1
Huang, TC1
Lee, HS1
Shah, S1
Chotigeat, U1
Jirapapa, K1
Layangkool, T1
Herrera, C2
Holberton, J2
Dollberg, S1
Lusky, A1
Reichman, B1
Distefano, G1
Brooks, JM2
Travadi, JN2
Patole, SK2
Doherty, DA2
Simmer, K1
Doyle, NM1
Gardner, MO1
Wells, L1
Qualls, C1
Papile, LA1
Lago, P1
Plebani, M2
Gimeno Navarro, A1
Cano Sánchez, A1
Fernández Gilino, C1
Carrasco Moreno, JI1
Izquierdo Macián, I1
Gutiérrez Laso, A1
Morcillo Sopena, F1
Hasan, SU1
Tacy, TA1
Fields, S1
Ofenstein, JP1
Clark, R1
Walker, MW1
Sperandio, M1
Beedgen, B1
Feneberg, R1
Huppertz, C1
Brüssau, J1
Pöschl, J1
Linderkamp, O2
Jaillard, S1
Larrue, B1
Rakza, T1
Magnenant, E1
Warembourg, H1
Storme, L1
Miller, SP1
Mayer, EE1
Glidden, DV1
Hamrick, SE1
Barkovich, AJ1
Manzar, S1
Paquette, L1
Friedlich, P1
Ramanathan, R1
Kumaran, V1
Godambe, S1
Newby, B1
Shah, V1
Shah, PS1
Pietz, J1
Achanti, B2
Lilien, L3
Stepka, EC1
Mehta, SK1
Kawase, Y1
Ishii, T1
Arai, H1
Uga, N1
Cordero, L1
Nankervis, CA1
Delooze, D1
Giannone, PJ1
Levene, M1
Cherif, A1
Jabnoun, S1
Khrouf, N1
Su, BH1
Lin, HC1
Chiu, HY1
Hsieh, HY1
Chen, HH1
Tsai, YC1
Amin, SB1
Sinkin, RA1
Glantz, JC1
Sangem, M1
Asthana, S1
Amin, S1
Kimura, R1
Lee, KS1
Herrman, K1
Bose, C1
Lewis, K1
Laughon, M1
Versmold, HT1
Raval, D5
Lilien, LD2
Srinivasan, G2
Pildes, RS10
Kääpä, P1
Lanning, P1
Koivisto, M2
Gersony, WM3
Peckham, GJ2
Ellison, RC3
Miettinen, OS2
Nadas, AS4
Pyati, S1
Drummond, WH1
Bucciarelli, RL1
Gessner, IH1
Monset-Couchard, M1
Dias-Mançano, D1
Murat, I2
Relier, JP1
Wagner, HR1
Zierler, S2
Lang, P2
Purohit, DM1
Behrendt, D1
Waldhausen, JA1
Seyberth, HW6
Rascher, W1
Wille, L3
Hackenthal, E1
Ulmer, HE2
Kraybill, EN1
Ohlsson, A1
Sieck, U1
Cumming, W1
Akhtar, M1
Serenius, F1
Tulassay, T1
Kiszel, J1
Csömör, S1
Regazzi, MB1
Rondanelli, R1
Vidale, E1
Chirico, G1
Rondini, G1
Chiara, A1
Piccolo, A1
Zarfin, Y2
Koren, G2
Perlman, M3
Dooley, KJ1
Smallhorn, JF1
Gow, R1
Olley, PM4
Freedom, RM1
Swyer, PR3
Rowe, RD3
Atik, E1
Moromizato, JH1
Zan, R1
Ajzenberg, M1
Esher, R1
Diniz, EM1
Souza, AT1
Martins, CO1
Bastos, JC1
Pedersen, S1
Frost, L1
Vázquez, C1
Cabrera, A2
Pastor, E2
Valls y Soler, A1
Petersen, S3
Christensen, NC3
Lauridsen, P2
Pedersen, SA2
Ryssing, E3
Laguenie, G1
Estève, C1
Couturier, C1
Saint-Maurice, JP1
Mellander, M1
Leheup, B1
Lindstrom, DP1
Palme, C1
Graham, TP1
Stahlman, MT1
Cotton, RB3
Corazza, MS1
Davis, RF1
Merritt, TA5
Bejar, R1
Cvetnic, W1
Chiswick, ML1
Blinova, EI1
Aleksi-Meskhishvili, VV1
Verboom, AJ1
de Leeuw, R1
Müller, H1
Plückthun, H1
Wolf, D1
Luken, J2
Thalji, A3
Carr, I3
O'Loughlin, JE1
Yanagi, RM1
Wilson, A1
Newfeld, EA1
Aziz, KU1
Hunt, CE1
Hencz, P1
Kertész, E1
Beviz, J1
Szeleczki, T1
Szekeres, Z1
Mahony, L1
Carnero, V1
Brett, C1
Heymann, MA5
Mullett, MD2
Croghan, TW1
Myerberg, DZ1
Krall, JM1
Neal, WA2
Burnard, ED1
Thomas, DB1
Grattan-Smith, P1
Wilks, A2
Singh, J1
Betkerur, M1
Goldbarg, HR1
Henek, T1
Friedman, CA1
Parks, BR1
Rawson, JE1
Serwer, GA1
Anderson, PA1
Harris, JP1
Alexson, CG1
Longfield, L1
Manning, JA1
Jaso, E1
Tejedor, JC1
Quero, J1
Pérez Rodríguez, J1
Agustí, B1
Castro, J1
García Frías, E1
Lozano González, CH1
Holden, AM1
Hurtado del Río, D1
Segura, MA1
Dalens, B1
Dechelotte, P1
Gaulme, J1
Raynaud, EJ1
Luken, L1
Møller Jensen, K1
Nagaraj, HS1
Sandhu, AS1
Cook, LN1
Buchino, JJ1
Groff, DB1
Neu, J1
Ariagno, RL1
Johnson, JD1
Pitlick, PT2
Cohen, RS1
Beets, CL1
Sunshine, P1
Evans, M1
Bhat, R1
Vidyasagar, D1
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Catterton, Z1
Sellers, B1
Gray, B1
Chantepie, A1
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Gray, PH1
Pemberton, PJ1
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Pankhurst, S1
Yu, VY4
Procianoy, RS1
Garcia-Prats, JA2
Hittner, HM1
Adams, JM1
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Yaffe, SJ1
Friedman, WF6
Rogers, D1
Ragni, M1
Saccar, C1
Thalji, AA1
Luken, JA1
de Veciana, M1
Porto, M1
Major, CA2
Barke, JI1
Patel, J1
Marks, KA1
Roberts, I1
Azzopardi, D1
Edwards, AD2
Glaser, J2
Schimmel, MS2
Ferber, B2
Eidelman, AI2
Ehrenkranz, RA5
Philip, AG2
Liem, KD2
Hopman, JC1
Kollée, LA1
Oeseburg, B1
Barrington, KJ1
Fox, M1
Merrill, JD1
Norton, ME2
Hebel, A1
Grasser, S1
Phillip, AG1
Taylor, KJ3
Merrill, J1
Cooper, BA1
Kuller, JA1
Archer, N3
Gal, P2
Gilman, JT1
Schneider, K1
Lewis, DF1
Harding, JA1
Porto, MA1
Garite, TJ1
Trus, T1
Winthrop, AL1
Pipe, S1
Shah, J1
Langer, JC1
Lau, GY1
Zangen, D1
Buderus, S1
Thomas, B1
Fahnenstich, H1
Kowalewski, S1
Renfro, WH1
Burr, JM1
Rawlings, J1
Couser, RJ1
Ferrara, TB1
Wright, GB1
Cabalka, AK1
Schilling, CG1
Hoekstra, RE1
Payne, NR1
Kirsten, D1
Grosfeld, JL1
Chaet, M1
Molinari, F1
Engle, W1
Engum, SA1
West, KW1
Rescorla, FJ1
Scherer, LR1
Scott, DT2
Bada, HS1
Bray, M1
Lattanzio, M1
Fumagalli, M1
Tosetto, C1
Yanowitz, TD1
Yao, AC1
Werner, JC1
Pettigrew, KD1
Souter, D1
Harding, J1
McCowan, L1
O'Donnell, C1
McLeay, E1
Baxendale, H1
Makuch, R1
Perez, CA1
Bustorff-Silva, JM1
Villasenor, E1
Fonkalsrud, EW1
Atkinson, JB1
Andruscavage, L1
Shorter, NA1
Liu, JY1
Mooney, DP1
Harmon, BJ1
Patole, S2
Whitehall, J2
Tammela, O3
Ojala, R3
Iivainen, T1
Lautamatti, V1
Pokela, ML1
Janas, M1
Ikonen, S2
Narayanan, M2
Schlueter, M1
Kang, NS1
Yoo, KH1
Cheon, H1
Choi, BM1
Hong, YS1
Lee, JW1
Kim, SK1
Vermillion, ST1
Newman, RB1
Watterberg, KL1
Scott, SM1
Backstrom, C1
Gifford, KL1
Cook, KL1
Sparrow, SS1
Cooper, B2
Weiss, H1
Patchakapati, B1
Zaninotto, M1
Lachin, M1
Altinier, S1
Ferrarese, P1
Brion, LP2
Campbell, DE2
Smets, K1
Lecoutere, D1
Van de Broek, H2
Weyler, J2
Degroote, K1
Langhendries, JP1
Van Laer, P1
Vanhaesebrouck, P2
Edstedt-Bonamy, AK1
Johansson, S1
Milerad, J1
Casalaz, D1
Suzumura, H1
Nitta, A1
Tanaka, G1
Arisaka, O1
Ruuska, T1
Karikoski, R1
Ikonen, RS1
Bolisetty, S1
Koh, G1
Stalewski, H1
Al-Shawaf, EM1
Al-Alaiyan, SA1
Aqeel, AY1
Gamal, MH1
Arlettaz, R1
Wilkinson, AR2
Robel-Tillig, E1
Knüpfer, M1
Pulzer, F1
Vogtmann, C2
Christmann, V1
Semmekrot, BA1
van de Bor, M1
Quinn, D1
Edwards, DK1
Higgins, CB1
DiSessa, TG1
Imre, S1
Katalin, P1
Bartel, J1
Fitzpatrick, KM1
Feldman, BH1
Cifuentes, RF1
Balfe, JW1
Radde, IC1
Polgár, M1
Kemény, J1
Szirmai, Z1
Van Kets, H1
Thiery, M2
Derom, R1
Van Egmond, H1
Baele, G1
Rudolph, AM3
Gluck, L1
Higgins, C1
Friedman, W1
Nyhan, WL1
Friedman, Z1
Demers, LM1
Marks, KH1
Uhrmann, S1
Maisels, MJ1
Hoffman, JI1
Edmunds, LH1
Hirschklau, MJ1
Printz, MP1
Kirkpatrick, SE1
Silverman, NH1
So, LY1
Fok, TF1
Sung, RY1
Ho, JK1
Morales-Suárez, M1
Lemus-Varela, L1
Udaeta-Mora, E1
Cardiel-Marmolejo, L1
Rodríguez-Balderrama, I1
Liz-Cedillo, RE1
Weir, FJ1
Smith, A1
Littleton, P1
Carter, N1
Hamilton, PA1
Austin, NC1
Pairaudeau, PW1
Hames, TK1
Hall, MA1
Sakhalkar, VS1
Merchant, RH1
Figueras Aloy, J1
Vilanova Juanola, JM1
Molina González, J1
Jiménez González, R1
Haywood, JL1
FitzGerald, GA1
Satur, CR1
Walker, DR1
Dickinson, DF1
Lamp, KC1
Reynolds, MS1
James, C1
Reed, MD1
Wyatt, JS1
Richardson, C1
Potter, A1
Cope, M1
Delpy, DT1
Reynolds, EO1
Fetter, WP1
Hop, WC1
Wallenburg, HC1
Spritzer, R1
Sauer, PJ1
Steinberg, JD1
Bambang Oetomo, S1
Martijn, A1
Messer, J1
Weisburd, P1
Haddad, J1
Willard, D1
Weninger, M2
Pollak, A2
Salzer-Muhar, U2
Vergesslich, KA1
Salzer, HR2
Volpe, JJ2
Foti, P1
Zambon, P1
Stellin, G1
Milanesi, O1
Strasser, T1
Vogel, M1
Wolf, WM1
Snover, DC1
Leonard, AS1
Sterniste, W1
Fürnkranz, H1
Patel, H1
Gonik, B1
Creasy, RK1
Colditz, P1
Murphy, D1
Rolfe, P1
Morselli, P1
Leroy, JG1
Govaert, P1
de Praeter, C1
Coppens, M1
Cuvelier, C1
Dhont, M1
Grubbe, G1
Ruckhäberle, KE1
Böttcher, H1
Ockert, C1
Walters, M1
Bandstra, ES1
Montalvo, BM1
Goldberg, RN1
Pacheco, I1
Ferrer, PL1
Flynn, J1
Gregorios, JB1
Bancalari, E1
Hwang, B1
Hsieh, KS1
Tsuei, DH1
Chen, SJ1
Meng, CC1
Perlman, JM1
Kresch, MJ1
Moya, FR1
Ascuitto, RJ1
Ross-Ascuitto, NT1
Heusser, F1
Pryds, O1
Greisen, G1
Johansen, KH1
Kauffman, RE1
Rennie, JM1
Doyle, J1
Cooke, RW1
Burghard, R2
Leititis, JU2
Brandis, M2
Leonhardt, A1
Isken, V1
Kühl, PG1
Szymonowicz, W1
Daniel, M1
Ho, NK1
Gordjani, N1
Wildberg, A1
Valls i Soler, A1
Benito, J1
López Heredia, I1
Santiago, M1
Evans, DH1
Levene, MI1
Archer, LN1
Marshall, CL1
Hayashi, RH1
Ho, LY1
Silove, ED1
Reinhardt, D1
Kusenbach, G1
Goldberg, SJ1
Ramsay, JM1
Murphy, DJ1
Vick, GW1
Courtney, JT1
Huhta, JC1
Page, GG1
Kleinman, CS1
Pitt, BR1
Stewart, WB1
Gettner, P1
Maresky, D1
MacLeod, S1
Kühl, G1
Bolkenius, M1
Lewis, IG1
Harvey, DP1
Maxwell, GM1

Clinical Trials (22)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Drug Utilization Patterns in Neonatal Units in the UK: a Retrospective Pharmaco-epidemiological Study[NCT03773289]642,729 participants (Actual)Observational2018-04-20Completed
Dynamic Prediction of Bleeding in Thrombocytopenic Preterm Neonates[NCT06043050]1,200 participants (Anticipated)Observational2022-09-26Recruiting
Long Term Follow-up of the TREOCAPA (Prophylactic TREatment Of the duCtus Arteriosus in Preterm Infants by Acetaminophen) Study (TREOCAPA-LT)[NCT06064825]500 participants (Anticipated)Observational2023-11-30Not yet recruiting
The Best Treatment Strategy: Surgical Versus Pharmacological, to Close the Ductus Arteriosus Persistent in Preterm Infants. A Randomized Controlled Trial[NCT02602054]Phase 240 participants (Anticipated)Interventional2015-10-31Recruiting
Randomized Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage (GMH/IVH) Prevention Trial[NCT00033917]Phase 3630 participants (Actual)Interventional1989-09-30Completed
Randomised Controlled Clinical Trial of Echocardiographically Guided Versus Standard Ibuprofen Treatment for Patent Ductus Arteriosus: a Pilot Study[NCT01593163]Phase 349 participants (Actual)Interventional2009-05-31Completed
Combination of Acetaminophen and Ibuprofen in the Management of Patent Ductus Arteriosus in Premature Infants: A Pilot Study[NCT03103022]Phase 120 participants (Actual)Interventional2017-06-12Completed
Randomized, Placebo Controlled Trial of Indomethacin for Tocolysis[NCT01869361]Early Phase 10 participants (Actual)Interventional2020-08-01Withdrawn (stopped due to Due to much lower than expected numbers of eligible patients and lack of PI time, the study was not started.)
Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)[NCT00009646]Phase 31,202 participants (Actual)Interventional1993-11-30Completed
Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253]Phase 344 participants (Anticipated)Interventional2016-03-31Completed
Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)[NCT02409680]11,976 participants (Actual)Interventional2016-03-23Completed
Paracetamol (Acetaminophen) for Closure of PDA in Preterm Infants[NCT01755728]Phase 319 participants (Actual)Interventional2013-01-01Completed
Lactoferrin Infant Feeding Trial - LIFT_Canada[NCT03367013]Phase 3453 participants (Actual)Interventional2018-02-16Active, not recruiting
Enteral Supplementation With High-dose Docosahexaenoic Acid on the Risk for Bronchopulmonary Dysplasia in Very Preterm Infants: A Collaborative Study Protocol for an Individual Participant Data Meta-analysis[NCT05915806]1,801 participants (Actual)Interventional2023-07-30Active, not recruiting
Clinical Research on the Predictive Effect of Neonatal Morbidities on the Poor Outcomes to Very Low Birth-weight and Extremely Low Birth-weight Infants[NCT03104946]834 participants (Actual)Observational2013-09-01Completed
Generic Database: A Survey of Morbidity and Mortality in Very Low Birth Weight Infants[NCT00063063]80,000 participants (Anticipated)Observational1987-01-31Recruiting
New Therapeutic Approaches to the Resistant Patent Ductus Arteriosus (PDA) in Low Birth Weight Neonates[NCT00616382]Phase 268 participants (Anticipated)Interventional2008-03-31Not yet recruiting
Intestinal Function in Neonates With Complex Congenital Heart Disease[NCT01475357]27 participants (Actual)Interventional2011-10-31Completed
Randomized Pilot Study Comparing Oral Ibuprofen With Intravenous Ibuprofen in Very Low Birth Weight Infants With Patent Ductus Arteriosus[NCT00642330]Phase 462 participants (Actual)Interventional2007-01-31Completed
[NCT00000494]Phase 30 participants Interventional1978-09-30Completed
Comparison of the Efficacy of IV Acetaminophen Versus IV Indomethacin in Treatment of Hemodynamically Significant PDA in VLBW Infants[NCT03537144]Phase 337 participants (Actual)Interventional2016-06-30Terminated (stopped due to Difficulty enrolling patients)
Pharmacological Closure of Patent Ductus Arteriosus in Extreme Low Birth Weight Infants. A Comparison of Efficacy, Side Effects and Outcomes Between Indomethacin and Ibuprofen[NCT01758913]110 participants (Actual)Interventional2007-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

IVH at 5 Postnatal Days

Cranial ultrasounds were performed daily for the first 5 postnatal days; the main outcome measure was intraaventricular hemorrhage (IVH) at 5 days of age (NCT00033917)
Timeframe: at 5 days

InterventionIVH (Number)
Indomethacin25
Placebo40

Language Outcome

"Peabody Picture Vocabulary Test (PPVT) This is a semantic language test. The mean value is 100; standard deviation is 16 points. A higher score means better language; a lower score means poorer language.~There are no subscales to the PPVT. The measurement unit is points on a scale. A score < 70 indicates severely abnormal language function." (NCT00033917)
Timeframe: at 8 years

Interventionparticipants with PPVT score < 70 (Number)
Indomethacin - no IVH12
Indomethacin - IVH5
Placebo - no IVH24
Placebo - IVH7

Fetal Outcome 1 - Incidence of Early Preterm Delivery (<34 Weeks)

- Early preterm delivery (<34 weeks) (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm189
Placebo Arm230

Fetal Outcome 2 - Incidence of Actual Birth Weight <2500g

- Birth weight <2500g (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm1078
Placebo Arm1153

Fetal Outcome 3 - Incidence of Actual Birth Weight <1500g

- Birth weight <1500g (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm78
Placebo Arm101

Fetal Outcome 4 - Incidence of Fetal Loss

- Incidence of Fetal Loss (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm303
Placebo Arm353

Fetal Outcome 5 - Incidence of Spontaneous Abortion

- Incidence of Spontaneous Abortion (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm134
Placebo Arm152

Fetal Outcome 6 - Incidence of All Stillbirth

- Incidence of All stillbirth (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm141
Placebo Arm166

Fetal Outcome 7 - Incidence of Medical Termination of Pregnancy

- Incidence of Medical Termination of Pregnancy (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm42
Placebo Arm30

Incidence of Hypertensive Disorders of Pregnancy

- Hypertensive disorders of pregnancy is defined by the characterization of evidence of a hypertensive disorder, including either preeclampsia or eclampsia occurring during the pregnancy. (NCT02409680)
Timeframe: Evidence of hypertensive disorder during the pregnancy (prior to delivery/birth)

InterventionParticipants (Count of Participants)
Intervention Arm352
Placebo Arm325

Incidence of Perinatal Mortality

- Incidence of Perinatal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm264
Placebo Arm309

Incidence of Preterm Birth

The primary outcome of this study is incidence of preterm birth, which will be defined as delivery at or after 20 0/7 weeks and prior to 37 0/7 weeks. This will be determined based on actual date of delivery in comparison to the projected estimated due date (EDD), independent of whether or not the preterm delivery is indicated or spontaneous. (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm668
Placebo Arm754

Incidence of Small for Gestational Age (SGA)

- Small for gestational age (SGA) as defined by the INTERGROWTH-21st standard (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm1506
Placebo Arm1564

Maternal Outcome 1 - Incidence of Vaginal Bleeding

- Vaginal bleeding (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm214
Placebo Arm246

Maternal Outcome 2 - Incidence of Antepartum Hemorrhage

- Antepartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm26
Placebo Arm25

Maternal Outcome 3 - Incidence of Postpartum Hemorrhage

- Postpartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm54
Placebo Arm43

Maternal Outcome 4 - Incidence of Maternal Mortality

- Incidence of Maternal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm9
Placebo Arm12

Maternal Outcome 5 - Incidence of Late Abortion

- Incidence of Late Abortion (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm23
Placebo Arm30

Maternal Outcome 6 - Change in Maternal Hemoglobin

Hemoglobin < 7.0 gm/dl at 26-30 weeks gestation or a drop of 3.5+ gm/dl from screening to 26-30 weeks gestation (NCT02409680)
Timeframe: At enrollment, 4 weeks post enrollment, and 26-30 weeks GA.

InterventionParticipants (Count of Participants)
Intervention Arm290
Placebo Arm333

Maternal Outcome 7 - Incidence of Preterm, Preeclampsia

Early preterm delivery (<34 weeks) and hypertensive disorders (i.e.: preeclampsia) (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm8
Placebo Arm21

Reviews

51 reviews available for indomethacin and Infant, Premature, Diseases

ArticleYear
The effectiveness of interventions to prevent intraventricular haemorrhage in premature infants: A systematic review and network meta-analysis.
    Journal of neonatal-perinatal medicine, 2023, Volume: 16, Issue:1

    Topics: Cerebral Hemorrhage; Humans; Indomethacin; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant

2023
Indomethacin for preterm infants with intracranial hemorrhage.
    Pediatrics international : official journal of the Japan Pediatric Society, 2013, Volume: 55, Issue:1

    Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Pre

2013
Therapeutic manipulation of the ductus arteriosus: current options and future prospects.
    Polskie Archiwum Medycyny Wewnetrznej, 2014, Volume: 124, Issue:1-2

    Topics: Ductus Arteriosus, Patent; Female; Forecasting; Hemodynamics; Humans; Ibuprofen; Indomethacin; Infan

2014
Nursing Assessment, Education, and Care of Extremely Premature Neonates with Patent Ductus Arteriosus.
    Current pediatric reviews, 2016, Volume: 12, Issue:2

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Extremely Low Bi

2016
Surgical Intervention in Preterm Neonates with Patent Ductus Arteriosus.
    Current pediatric reviews, 2016, Volume: 12, Issue:2

    Topics: Bronchopulmonary Dysplasia; Combined Modality Therapy; Cyclooxygenase Inhibitors; Ductus Arteriosus,

2016
Understanding clinical literature relevant to spontaneous intestinal perforations.
    American journal of perinatology, 2009, Volume: 26, Issue:4

    Topics: Acute Disease; Bacterial Infections; Critical Care; Dexamethasone; Drug Therapy, Combination; Female

2009
Therapeutic closure of the ductus arteriosus: benefits and limitations.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2009, Volume: 22 Suppl 3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Evidence-Based Medicine; Gestati

2009
Nonsteroidal anti-inflammatory drugs (NSAIDs) in the newborn - which ones?
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2009, Volume: 22 Suppl 3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Hemorrhage; Humans; Ibuprofen; I

2009
Treatment of persistent patent ductus arteriosus in preterm infants: time to accept the null hypothesis?
    Journal of perinatology : official journal of the California Perinatal Association, 2010, Volume: 30, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiac Surgical Procedures; Confidence Intervals; Ductus A

2010
Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants.
    The Cochrane database of systematic reviews, 2010, Jul-07, Issue:7

    Topics: Cardiovascular Agents; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant,

2010
Network meta-analysis of indomethacin versus ibuprofen versus placebo for PDA in preterm infants.
    Archives of disease in childhood. Fetal and neonatal edition, 2011, Volume: 96, Issue:1

    Topics: Cardiovascular Agents; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprof

2011
Patent ductus arteriosus: wait and see?
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2011, Volume: 24 Suppl 3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin;

2011
Should we definitively abandon prophylaxis for patent ductus arteriosus in preterm new-borns?
    Clinics (Sao Paulo, Brazil), 2011, Volume: 66, Issue:12

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Extre

2011
Tocolytic therapy for acute preterm labor.
    Obstetrics and gynecology clinics of North America, 2012, Volume: 39, Issue:1

    Topics: Calcium Channel Blockers; Drug Administration Schedule; Female; Gestational Age; Humans; Indomethaci

2012
Tocolytic therapy for acute preterm labor.
    Obstetrics and gynecology clinics of North America, 2012, Volume: 39, Issue:1

    Topics: Calcium Channel Blockers; Drug Administration Schedule; Female; Gestational Age; Humans; Indomethaci

2012
Tocolytic therapy for acute preterm labor.
    Obstetrics and gynecology clinics of North America, 2012, Volume: 39, Issue:1

    Topics: Calcium Channel Blockers; Drug Administration Schedule; Female; Gestational Age; Humans; Indomethaci

2012
Tocolytic therapy for acute preterm labor.
    Obstetrics and gynecology clinics of North America, 2012, Volume: 39, Issue:1

    Topics: Calcium Channel Blockers; Drug Administration Schedule; Female; Gestational Age; Humans; Indomethaci

2012
The ductus arteriosus: a refined approach!
    Seminars in perinatology, 2012, Volume: 36, Issue:2

    Topics: Biomarkers; Cyclooxygenase Inhibitors; Decision Making; Ductus Arteriosus, Patent; Echocardiography;

2012
Managing the patent ductus arteriosus in the premature neonate: a new look at what we thought we knew.
    Seminars in perinatology, 2012, Volume: 36, Issue:2

    Topics: Acetaminophen; Biomarkers; Dose-Response Relationship, Drug; Ductus Arteriosus, Patent; Echocardiogr

2012
Patent ductus arteriosus: are current neonatal treatment options better or worse than no treatment at all?
    Seminars in perinatology, 2012, Volume: 36, Issue:2

    Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Inf

2012
Segmental absence of intestinal musculature: an increasingly reported pathology.
    Journal of pediatric surgery, 2012, Volume: 47, Issue:8

    Topics: Abdomen, Acute; Abnormalities, Multiple; Adult; Cesarean Section; Digestive System Abnormalities; Du

2012
[Progresses in treatment of patent ductus arteriosus in premature infants].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2012, Volume: 50, Issue:11

    Topics: Ductus Arteriosus; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Wei

2012
Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants.
    The Cochrane database of systematic reviews, 2002, Issue:3

    Topics: Cardiovascular Agents; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant,

2002
Prophylactic indomethacin for preterm infants: a systematic review and meta-analysis.
    Archives of disease in childhood. Fetal and neonatal edition, 2003, Volume: 88, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorrhage; Humans; Indomethacin; Infant, Newborn;

2003
Should a prolonged or short course of indomethacin be used in preterm infants to treat patent ductus arteriosus?
    Archives of disease in childhood, 2003, Volume: 88, Issue:12

    Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Pre

2003
Prolonged versus short course of indomethacin for the treatment of patent ductus arteriosus in preterm infants.
    The Cochrane database of systematic reviews, 2004, Issue:1

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Prematu

2004
[The pharmacological manipulation of Botallo's duct in the duct-dependent congenital cardiopathies and in the preterm infants with respiratory distress. A review and personal findings].
    Minerva pediatrica, 2005, Volume: 57, Issue:1

    Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Agents; Cerebral Angiography; C

2005
Systematic review: intravenous Ibuprofen in preterm newborns.
    Seminars in perinatology, 2006, Volume: 30, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indom

2006
Minimising neonatal brain injury: how research in the past five years has changed my clinical practice.
    Archives of disease in childhood, 2007, Volume: 92, Issue:3

    Topics: Animals; Birth Injuries; Brain Diseases; Dexamethasone; Disease Models, Animal; Ethamsylate; Humans;

2007
Prolonged versus short course of indomethacin for the treatment of patent ductus arteriosus in preterm infants.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Prematu

2007
Metaanalysis of the effect of antenatal indomethacin on neonatal outcomes.
    American journal of obstetrics and gynecology, 2007, Volume: 197, Issue:5

    Topics: Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant

2007
The ductus arteriosus: why and how to manipulate its patency.
    The Journal of the Florida Medical Association, 1983, Volume: 70, Issue:9

    Topics: Alprostadil; Ductus Arteriosus, Patent; Gestational Age; Heart Defects, Congenital; Humans; Indometh

1983
[Patent ductus arteriosus in premature infants (review of the literature)].
    Pediatriia, 1982, Issue:1

    Topics: Aortography; Carbon Dioxide; Digoxin; Diuretics; Ductus Arteriosus, Patent; Echocardiography; Electr

1982
The problem of ductal patency in prematures.
    Pediatric annals, 1981, Volume: 10, Issue:4

    Topics: Cardiac Catheterization; Digoxin; Ductus Arteriosus, Patent; Echocardiography; Electrocardiography;

1981
Patent ductus arteriosus. Clinical relevance of prostaglandins and prostaglandin inhibitors in PDA pathophysiology and treatment.
    Clinics in perinatology, 1995, Volume: 22, Issue:2

    Topics: Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Infant,

1995
Patent ductus arteriosus in the newborn.
    Archives of disease in childhood, 1993, Volume: 69, Issue:5 Spec No

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Prematu

1993
Drug disposition in neonates with patent ductus arteriosus.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:11

    Topics: Absorption; Anti-Bacterial Agents; Digoxin; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant,

1993
Recommendations for the postnatal use of indomethacin: an analysis of four separate treatment strategies.
    The Journal of pediatrics, 1996, Volume: 128, Issue:5 Pt 1

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Prematu

1996
Patent ductus arteriosus in the preterm infant.
    Neonatal network : NN, 1996, Volume: 15, Issue:2

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant,

1996
Routine indomethacin prophylaxis: has the time come?
    Pediatrics, 1996, Volume: 98, Issue:4 Pt 1

    Topics: Cerebral Hemorrhage; Cyclooxygenase Inhibitors; Humans; Indomethacin; Infant, Newborn; Infant, Prema

1996
Intravenous indomethacin for preventing mortality and morbidity in very low birth weight infants.
    The Cochrane database of systematic reviews, 2000, Issue:2

    Topics: Cardiovascular Agents; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant,

2000
Furosemide for symptomatic patent ductus arteriosus in indomethacin-treated infants.
    The Cochrane database of systematic reviews, 2000, Issue:2

    Topics: Cyclooxygenase Inhibitors; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Indomethacin; I

2000
Furosemide for symptomatic patent ductus arteriosus in indomethacin-treated infants.
    The Cochrane database of systematic reviews, 2001, Issue:3

    Topics: Cyclooxygenase Inhibitors; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Indomethacin; I

2001
[Drug therapy of patent ductus arteriosus in premature and newborn infants].
    Kinderarztliche Praxis, 1978, Volume: 46, Issue:12

    Topics: Apnea; Aspirin; Chloroquine; Digitalis Glycosides; Ductus Arteriosus, Patent; Humans; Indomethacin;

1978
The patent ductus arteriosus.
    Clinics in perinatology, 1978, Volume: 5, Issue:2

    Topics: Acute Kidney Injury; Animals; Clinical Trials as Topic; Ductus Arteriosus; Ductus Arteriosus, Patent

1978
[Pathogenic factors in bronchopulmonary dysplasia].
    Anales espanoles de pediatria, 1991, Volume: 35, Issue:1

    Topics: Birth Weight; Bronchopulmonary Dysplasia; Gestational Age; Humans; Iatrogenic Disease; Indomethacin;

1991
Indomethacin for prevention of neonatal intraventricular hemorrhage.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:12

    Topics: Birth Weight; Cerebral Hemorrhage; Cerebral Ventricles; Female; Humans; Indomethacin; Infant, Newbor

1991
Intraventricular hemorrhage in the premature infant--current concepts. Part II.
    Annals of neurology, 1989, Volume: 25, Issue:2

    Topics: Cerebral Hemorrhage; Cerebral Ventricles; Combined Modality Therapy; Echoencephalography; Ethamsylat

1989
Oligohydramnios, renal insufficiency, and ileal perforation in preterm infants after intrauterine exposure to indomethacin.
    The Journal of pediatrics, 1988, Volume: 113, Issue:4

    Topics: Amniotic Fluid; Female; Gastrointestinal Hemorrhage; Humans; Ileal Diseases; Indomethacin; Infant, L

1988
The relationship of symptomatic patent ductus arteriosus to respiratory distress in premature newborn infants.
    Clinics in perinatology, 1987, Volume: 14, Issue:3

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Ligat

1987
Prevention of neonatal intraventricular hemorrhage.
    Clinical neuropharmacology, 1987, Volume: 10, Issue:2

    Topics: Cerebral Hemorrhage; Cerebral Ventricles; Cerebrovascular Circulation; Ethamsylate; Humans; Indometh

1987
Therapeutic interventions to prevent intracerebral hemorrhage in preterm infants.
    The Journal of pediatrics, 1986, Volume: 108, Issue:2

    Topics: Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials as Topic; Ethamsylate; Humans; Ind

1986
Patent ductus arteriosus in the neonate.
    Pediatric clinics of North America, 1986, Volume: 33, Issue:3

    Topics: Alprostadil; Blood Circulation; Clinical Trials as Topic; Digoxin; Ductus Arteriosus; Ductus Arterio

1986
Patent ductus arteriosus in the premature neonate.
    Heart & lung : the journal of critical care, 1985, Volume: 14, Issue:2

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Ligat

1985

Trials

69 trials available for indomethacin and Infant, Premature, Diseases

ArticleYear
Effect of Prophylactic Indomethacin in Extremely Low Birth Weight Infants Based on the Predicted Risk of Severe Intraventricular Hemorrhage.
    Neonatology, 2018, Volume: 113, Issue:2

    Topics: Birth Weight; Cerebral Hemorrhage; Cyclooxygenase Inhibitors; Drug Administration Schedule; Female;

2018
A randomised placebo-controlled trial of early treatment of the patent ductus arteriosus.
    Archives of disease in childhood. Fetal and neonatal edition, 2014, Volume: 99, Issue:2

    Topics: Brain; Cyclooxygenase Inhibitors; Double-Blind Method; Ductus Arteriosus, Patent; Echocardiography,

2014
A Comparison of Early Ibuprofen and Indomethacin Administration to Prevent Intraventricular Hemorrhage Among Preterm Infants.
    Acta medica Iranica, 2016, Volume: 54, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorrhage; Cyclooxygenase Inhibitors; Ductus Arte

2016
Pharmacological closure of patent ductus arteriosus: effects on pulse pressure and on endothelin-1 and vasopressin excretion.
    American journal of perinatology, 2008, Volume: 25, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Blood Pressure; Ductus Arteriosus, Pa

2008
B-type natriuretic peptide concentrations to guide treatment of patent ductus arteriosus.
    Archives of disease in childhood. Fetal and neonatal edition, 2009, Volume: 94, Issue:3

    Topics: Biomarkers; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography; Female; Humans;

2009
Lasting effects of preterm birth and neonatal brain hemorrhage at 12 years of age.
    Pediatrics, 2009, Volume: 123, Issue:3

    Topics: Brain Damage, Chronic; Cerebral Ventricles; Child; Child Behavior Disorders; Child, Preschool; Cogni

2009
Trajectories of receptive language development from 3 to 12 years of age for very preterm children.
    Pediatrics, 2009, Volume: 124, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Brain Damage, Chronic; Cerebral Hemorrhage; Child; Child, P

2009
Duration of indomethacin treatment of the preterm patent ductus arteriosus as directed by echocardiography.
    The Journal of pediatrics, 2009, Volume: 155, Issue:6

    Topics: Cyclooxygenase Inhibitors; Drug Administration Schedule; Ductus Arteriosus, Patent; Echocardiography

2009
Effect of indomethacin infused over 30 minutes on cerebral fractional tissue oxygen extraction in preterm newborns with a patent ductus arteriosus.
    Neonatology, 2010, Volume: 98, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Cerebrum; Ductus Arteriosus, Patent; Female

2010
Effects of prophylactic indomethacin in extremely low-birth-weight infants with and without adequate exposure to antenatal corticosteroids.
    Archives of pediatrics & adolescent medicine, 2011, Volume: 165, Issue:7

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Developmental Disabilities; Female

2011
Effects of prophylactic indomethacin on renal and intestinal blood flows in premature infants.
    Pediatrics international : official journal of the Japan Pediatric Society, 2012, Volume: 54, Issue:4

    Topics: Cerebral Hemorrhage; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Infan

2012
Ibuprofen prophylaxis in preterm neonates.
    Lancet (London, England), 2002, Aug-10, Volume: 360, Issue:9331

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Hypertension, Pulmonary; Hypoxia; Ibup

2002
Oral ibuprofen and indomethacin for treatment of patent ductus arteriosus in premature infants: a randomized trial at Ramathibodi Hospital.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2002, Volume: 85 Suppl 4

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Hu

2002
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Impact of bronchopulmonary dysplasia, brain injury, and severe retinopathy on the outcome of extremely low-birth-weight infants at 18 months: results from the trial of indomethacin prophylaxis in preterms.
    JAMA, 2003, Mar-05, Volume: 289, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blindness; Brain Diseases; Bronchopulmonary Dysplasia; Cere

2003
Randomized trial of prolonged low-dose versus conventional-dose indomethacin for treating patent ductus arteriosus in very low birth weight infants.
    Pediatrics, 2003, Volume: 112, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Administration Schedule; Ductus Arteriosus, Patent; Ec

2003
Effect of early targeted indomethacin on the ductus arteriosus and blood flow to the upper body and brain in the preterm infant.
    Archives of disease in childhood. Fetal and neonatal edition, 2003, Volume: 88, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorrhage; Cerebrovascular Circulation; Cross-Ove

2003
Comparison of ibuprofen and indomethacin therapy for patent ductus arteriosus in preterm infants.
    Pediatrics international : official journal of the Japan Pediatric Society, 2003, Volume: 45, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Femal

2003
A comparison of oral ibuprofen and intravenous indomethacin for closure of patent ductus arteriosus in preterm infants.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2003, Volume: 86 Suppl 3

    Topics: Administration, Oral; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofe

2003
[Ibuprofen versus indomethacin in the treatment of patent ductus arteriosus in preterm infants].
    Anales de pediatria (Barcelona, Spain : 2003), 2005, Volume: 63, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indom

2005
Combined treatment with a nonselective nitric oxide synthase inhibitor (l-NMMA) and indomethacin increases ductus constriction in extremely premature newborns.
    Pediatric research, 2005, Volume: 58, Issue:6

    Topics: Drug Therapy, Combination; Ductus Arteriosus; Ductus Arteriosus, Patent; Enzyme Inhibitors; Female;

2005
Comparison of ibuprofen and indometacin for early-targeted treatment of patent ductus arteriosus in extremely premature infants: a randomised controlled trial.
    Archives of disease in childhood. Fetal and neonatal edition, 2008, Volume: 93, Issue:2

    Topics: Analysis of Variance; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ductus Arteriosus

2008
Decreased plasma glucose after indomethacin therapy in premature infants with patent ductus anteriosus.
    Lancet (London, England), 1982, Jul-10, Volume: 2, Issue:8289

    Topics: Blood Glucose; Clinical Trials as Topic; Double-Blind Method; Ductus Arteriosus, Patent; Humans; Ind

1982
Early closure of patent ductus arteriosus with indomethacin in preterm infants with idiopathic respiratory distress syndrome.
    Acta paediatrica Scandinavica, 1983, Volume: 72, Issue:2

    Topics: Clinical Trials as Topic; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant,

1983
Effects of indomethacin in premature infants with patent ductus arteriosus: results of a national collaborative study.
    The Journal of pediatrics, 1983, Volume: 102, Issue:6

    Topics: Clinical Trials as Topic; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant,

1983
Effects of indomethacin in premature infants with patent ductus arteriosus: results of a national collaborative study.
    The Journal of pediatrics, 1983, Volume: 102, Issue:6

    Topics: Clinical Trials as Topic; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant,

1983
Effects of indomethacin in premature infants with patent ductus arteriosus: results of a national collaborative study.
    The Journal of pediatrics, 1983, Volume: 102, Issue:6

    Topics: Clinical Trials as Topic; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant,

1983
Effects of indomethacin in premature infants with patent ductus arteriosus: results of a national collaborative study.
    The Journal of pediatrics, 1983, Volume: 102, Issue:6

    Topics: Clinical Trials as Topic; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant,

1983
Retinopathy of prematurity (ROP) and indomethacin therapy in premature infants with patent ductus arteriosus (PDA).
    Prostaglandins, 1983, Volume: 25, Issue:3

    Topics: Clinical Trials as Topic; Ductus Arteriosus, Patent; Gestational Age; Humans; Indomethacin; Infant,

1983
[Controlled trial of intravenous lyophilized indomethacin in the treatment of persistent ductus arteriosus in premature infants].
    Pediatrie, 1983, Volume: 38, Issue:6

    Topics: Clinical Trials as Topic; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn;

1983
Surgical closure of patent ductus arteriosus in 268 preterm infants.
    The Journal of thoracic and cardiovascular surgery, 1984, Volume: 87, Issue:6

    Topics: Clinical Trials as Topic; Double-Blind Method; Ductus Arteriosus, Patent; Female; Humans; Indomethac

1984
Clinical course to 1 year of age in premature infants with patent ductus arteriosus: results of a multicenter randomized trial of indomethacin.
    The Journal of pediatrics, 1984, Volume: 105, Issue:2

    Topics: Bronchopulmonary Dysplasia; Child Development; Clinical Trials as Topic; Combined Modality Therapy;

1984
The use of dopamine for the prevention of the renal side effects of indomethacin in premature infants with patent ductus arteriosus.
    The International journal of pediatric nephrology, 1984, Volume: 5, Issue:4

    Topics: Clinical Trials as Topic; Dopamine; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn

1984
Mannheimer lecture.
    Pediatric cardiology, 1982, Volume: 3, Issue:1

    Topics: Clinical Trials as Topic; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant,

1982
Decreased plasma glucose following indomethacin therapy in premature infants with patent ductus arteriosus.
    Pediatric pharmacology (New York, N.Y.), 1982, Volume: 2, Issue:3

    Topics: Blood Glucose; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature,

1982
Indomethacin treatment for symptomatic patent ductus arteriosus: a double-blind control study.
    Pediatrics, 1981, Volume: 67, Issue:5

    Topics: Clinical Trials as Topic; Double-Blind Method; Ductus Arteriosus, Patent; Gastrointestinal Hemorrhag

1981
Prophylactic indomethacin therapy for patent ductus arteriosus in very-low-birth-weight infants.
    The New England journal of medicine, 1982, Mar-04, Volume: 306, Issue:9

    Topics: Clinical Trials as Topic; Double-Blind Method; Ductus Arteriosus, Patent; Female; Hemodynamics; Huma

1982
Indomethacin for closure of patent ductus arteriosus in prematures.
    Clinical pediatrics, 1982, Volume: 21, Issue:4

    Topics: Clinical Trials as Topic; Double-Blind Method; Ductus Arteriosus, Patent; Enterocolitis, Pseudomembr

1982
Furosemide prevents the renal side effects of indomethacin therapy in premature infants with patent ductus arteriosus.
    The Journal of pediatrics, 1982, Volume: 101, Issue:3

    Topics: Drug Therapy, Combination; Ductus Arteriosus, Patent; Furosemide; Humans; Indomethacin; Infant, Newb

1982
Intravenous indomethacin therapy in premature infants with patent ductus arteriosus. Causes of death and one-year follow-up.
    American journal of diseases of children (1960), 1982, Volume: 136, Issue:9

    Topics: Double-Blind Method; Ductus Arteriosus, Patent; Follow-Up Studies; Humans; Indomethacin; Infant, New

1982
Improved lung compliance following indomethacin therapy in premature infants with persistent ductus arteriosus.
    Chest, 1981, Volume: 80, Issue:6

    Topics: Birth Weight; Blood Gas Analysis; Gestational Age; Humans; Hydrogen-Ion Concentration; Indomethacin;

1981
A double blind study of the effects of oral indomethacin in preterm infants with patent ductus arteriosus who failed medical management.
    Pediatric pharmacology (New York, N.Y.), 1981, Volume: 1, Issue:3

    Topics: Double-Blind Method; Drug Evaluation; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newbo

1981
Tocolysis in advanced preterm labor: impact on neonatal outcome.
    American journal of perinatology, 1995, Volume: 12, Issue:4

    Topics: Cohort Studies; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Magnesiu

1995
Continuous versus multiple rapid infusions of indomethacin: effects on cerebral blood flow velocity.
    Pediatrics, 1995, Volume: 95, Issue:2

    Topics: Blood Flow Velocity; Cerebrovascular Circulation; Depression, Chemical; Ductus Arteriosus, Patent; E

1995
Antenatal steroids, delivery mode, and intraventricular hemorrhage in preterm infants.
    American journal of obstetrics and gynecology, 1995, Volume: 172, Issue:3

    Topics: Cerebral Hemorrhage; Cesarean Section; Female; Humans; Indomethacin; Infant, Low Birth Weight; Infan

1995
Effects of repeated indomethacin administration on cerebral oxygenation and haemodynamics in preterm infants: combined near infrared spectrophotometry and Doppler ultrasound study.
    European journal of pediatrics, 1994, Volume: 153, Issue:7

    Topics: Blood Flow Velocity; Brain; Cerebrovascular Circulation; Ductus Arteriosus, Patent; Female; Humans;

1994
Low-dose indomethacin therapy and extension of intraventricular hemorrhage: a multicenter randomized trial.
    The Journal of pediatrics, 1994, Volume: 124, Issue:6

    Topics: Cerebral Hemorrhage; Drug Administration Schedule; Ductus Arteriosus, Patent; Female; Humans; Indome

1994
Risk period for intraventricular hemorrhage of the preterm neonate is independent of gestational age.
    Seminars in perinatology, 1993, Volume: 17, Issue:5

    Topics: Age of Onset; Cerebral Hemorrhage; Cerebral Ventricles; Gestational Age; Humans; Indomethacin; Infan

1993
Prophylactic indomethacin therapy in the first twenty-four hours of life for the prevention of patent ductus arteriosus in preterm infants treated prophylactically with surfactant in the delivery room.
    The Journal of pediatrics, 1996, Volume: 128, Issue:5 Pt 1

    Topics: Birth Weight; Ductus Arteriosus, Patent; Electrocardiography; Female; Humans; Indomethacin; Infant,

1996
Increased risk of necrotizing enterocolitis in premature infants with patent ductus arteriosus treated with indomethacin.
    Annals of surgery, 1996, Volume: 224, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Enterocolitis, Pseudomembranous;

1996
Neurodevelopmental outcome at 36 months' corrected age of preterm infants in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial.
    Pediatrics, 1996, Volume: 98, Issue:4 Pt 1

    Topics: Cerebral Hemorrhage; Chi-Square Distribution; Child Development; Child, Preschool; Cyclooxygenase In

1996
Comparative evaluation of the effects of indomethacin and ibuprofen on cerebral perfusion and oxygenation in preterm infants with patent ductus arteriosus.
    The Journal of pediatrics, 1997, Volume: 131, Issue:4

    Topics: Blood Flow Velocity; Brain; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Dose-Response Re

1997
Cognitive outcome at 4 1/2 years of very low birth weight infants enrolled in the multicenter indomethacin intraventricular hemorrhage prevention trial.
    Pediatrics, 1998, Volume: 102, Issue:1 Pt 1

    Topics: Brain Damage, Chronic; Cerebral Hemorrhage; Cerebral Ventricles; Child, Preschool; Cyclooxygenase In

1998
Short versus prolonged indomethacin therapy for patent ductus arteriosus in preterm infants.
    The Journal of pediatrics, 1999, Volume: 134, Issue:5

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography; Gestational Age; Humans; Ind

1999
Outcome of children in the indomethacin intraventricular hemorrhage prevention trial.
    Pediatrics, 2000, Volume: 105, Issue:3 Pt 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Brain Damage, Chronic; Cerebral Hemorrhage; Cerebral Ventri

2000
Prophylactic indomethacin: factors determining permanent ductus arteriosus closure.
    The Journal of pediatrics, 2000, Volume: 136, Issue:3

    Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Inf

2000
Indomethacin prophylaxis for patent ductus arteriosus (PDA) in infants with a birth weight of less than 1250 grams.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1999, Volume: 82 Suppl 1

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn;

1999
A comparison of ibuprofen and indomethacin for closure of patent ductus arteriosus.
    The New England journal of medicine, 2000, Sep-07, Volume: 343, Issue:10

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newbo

2000
Early versus late indomethacin treatment for patent ductus arteriosus in premature infants with respiratory distress syndrome.
    The Journal of pediatrics, 2001, Volume: 138, Issue:2

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Injec

2001
The use of indomethacin for the prevention of intraventricular brain hemorrhage in high-risk neonates.
    Saudi medical journal, 2000, Volume: 21, Issue:3

    Topics: Birth Weight; Cerebral Hemorrhage; Cerebral Ventricles; Cohort Studies; Gestational Age; Humans; Inc

2000
Changes in cerebral, renal and mesenteric blood flow velocity during continuous and bolus infusion of indomethacin.
    Acta paediatrica (Oslo, Norway : 1992), 2002, Volume: 91, Issue:4

    Topics: Blood Flow Velocity; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Ductus Arteriosus, Pate

2002
The patent ductus arteriosus.
    Clinics in perinatology, 1978, Volume: 5, Issue:2

    Topics: Acute Kidney Injury; Animals; Clinical Trials as Topic; Ductus Arteriosus; Ductus Arteriosus, Patent

1978
[Indomethacin in the prevention of subependymal-intraventricular hemorrhage in preterm newborns with conventional mechanical ventilation].
    Boletin medico del Hospital Infantil de Mexico, 1992, Volume: 49, Issue:4

    Topics: Cerebral Hemorrhage; Double-Blind Method; Ependyma; Humans; Indomethacin; Infant, Newborn; Infant, P

1992
Intravenous indomethacin therapy in preterm neonates with patent ductus arteriosus.
    Journal of paediatrics and child health, 1991, Volume: 27, Issue:6

    Topics: Ductus Arteriosus, Patent; Echocardiography, Doppler; Humans; Indomethacin; Infant, Newborn; Infant,

1991
Symptomatic patent ductus arteriosus following prophylactic indomethacin. A clinical and biochemical appraisal.
    Biology of the neonate, 1991, Volume: 60, Issue:5

    Topics: Dinoprostone; Ductus Arteriosus, Patent; Epoprostenol; High-Frequency Ventilation; Humans; Indometha

1991
Effects of indomethacin on cerebral haemodynamics in very preterm infants.
    Lancet (London, England), 1990, Jun-23, Volume: 335, Issue:8704

    Topics: Blood Gas Monitoring, Transcutaneous; Blood Pressure; Blood Volume; Cerebrovascular Circulation; Dru

1990
[Treatment of patent ductus arteriosus in premature infants by indomethacin].
    Presse medicale (Paris, France : 1983), 1987, Jun-06, Volume: 16, Issue:21

    Topics: Diuresis; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Disea

1987
[Effects of early therapy with indomethacin on the manifestation of a persistent ductus arteriosus in extremely underweight premature infants].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1988, Volume: 136, Issue:9

    Topics: Birth Weight; Clinical Trials as Topic; Drug Administration Schedule; Ductus Arteriosus, Patent; Fem

1988
Prophylactic indomethacin for prevention of intraventricular hemorrhage in premature infants.
    Pediatrics, 1988, Volume: 82, Issue:4

    Topics: Birth Weight; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant,

1988
Therapeutic interventions to prevent intracerebral hemorrhage in preterm infants.
    The Journal of pediatrics, 1986, Volume: 108, Issue:2

    Topics: Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials as Topic; Ethamsylate; Humans; Ind

1986
Early administration of indomethacin to preterm infants.
    Archives of disease in childhood, 1986, Volume: 61, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Clinical Trials as Topic; Double-Blind Method; Drug Administration Sch

1986
Patent ductus arteriosus in the neonate.
    Pediatric clinics of North America, 1986, Volume: 33, Issue:3

    Topics: Alprostadil; Blood Circulation; Clinical Trials as Topic; Digoxin; Ductus Arteriosus; Ductus Arterio

1986
Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants.
    The Journal of pediatrics, 1985, Volume: 107, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Cerebral Hemorrhage; Clinical Trials as Topic; Ductus Arteriosus, Pate

1985

Other Studies

203 other studies available for indomethacin and Infant, Premature, Diseases

ArticleYear
Effects of prophylactic indomethacin on intraventricular hemorrhage and adverse outcomes in neonatal intensive care unit.
    Journal of perinatology : official journal of the California Perinatal Association, 2022, Volume: 42, Issue:12

    Topics: Cerebral Hemorrhage; Child; Gestational Age; Humans; Indomethacin; Infant; Infant, Extremely Prematu

2022
Neurodevelopment at 5 Years of Age According to Early Screening for Patent Ductus Arteriosus in Extremely Preterm Infants.
    JAMA, 2022, 07-05, Volume: 328, Issue:1

    Topics: Child Development; Child, Preschool; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Extrem

2022
Management of patent ductus arteriosus in very preterm infants in England and Wales: a retrospective cohort study.
    BMJ paediatrics open, 2022, Volume: 6, Issue:1

    Topics: Ductus Arteriosus, Patent; Female; Fetal Growth Retardation; Humans; Ibuprofen; Indomethacin; Infant

2022
Indomethacin dosing strategy and neonatal patent ductus arteriosus closure.
    Journal of neonatal-perinatal medicine, 2019, Volume: 12, Issue:4

    Topics: Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ductus Arteriosus, Patent; Female; Gest

2019
Intensive and prolonged urine collection in preterm infants reveals three distinct indomethacin metabolic patterns: potential implications for drug dosing.
    Pediatric research, 2018, Volume: 84, Issue:3

    Topics: Drug Administration Schedule; Ductus Arteriosus, Patent; Female; Glucuronides; Humans; Indomethacin;

2018
Does Postmenstrual Age Affect Medical Patent Ductus Arteriosus Treatment Success in Preterm Infants?
    American journal of perinatology, 2019, Volume: 36, Issue:14

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Gestational Age; Humans;

2019
Effectiveness and Renal Functions Safety of Treatments Used for Neonates with Patent Ductus Arteriosus: A Prospective Cohort Study.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, May-17, Volume: 25

    Topics: Acetaminophen; Acute Kidney Injury; China; Cohort Studies; Ductus Arteriosus, Patent; Female; Humans

2019
Optimal timing of video-assisted thoracoscopic surgery for patent ductus arteriosus in preterm infants born at ≤ 28 weeks of gestation.
    Pediatrics international : official journal of the Japan Pediatric Society, 2019, Volume: 61, Issue:8

    Topics: Age Factors; Cardiovascular Agents; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant,

2019
Vascular endothelial growth factor polymorphism rs2010963 status does not affect patent ductus arteriosus incidence or cyclooxygenase inhibitor treatment success in preterm infants.
    Cardiology in the young, 2019, Volume: 29, Issue:7

    Topics: Case-Control Studies; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofe

2019
Tocolytic indomethacin: effects on neonatal haemodynamics and cerebral autoregulation in the preterm newborn.
    Archives of disease in childhood. Fetal and neonatal edition, 2013, Volume: 98, Issue:5

    Topics: Brain; Case-Control Studies; Cerebrovascular Circulation; Female; Gestational Age; Hemodynamics; Hom

2013
Indomethacin prophylaxis to prevent intraventricular hemorrhage: association between incidence and timing of drug administration.
    The Journal of pediatrics, 2013, Volume: 163, Issue:3

    Topics: Cerebral Hemorrhage; Cyclooxygenase Inhibitors; Drug Administration Schedule; Female; Follow-Up Stud

2013
Bartter syndrome: presentation in an extremely premature neonate.
    Journal of perinatology : official journal of the California Perinatal Association, 2013, Volume: 33, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Bartter Syndrome; Female; Humans; Indomethacin; Infant, Ext

2013
Preoperative left ventricular internal dimension in end-diastole as earlier identification of early patent ductus arteriosus operation and postoperative intensive care in very low birth weight infants.
    Early human development, 2013, Volume: 89, Issue:10

    Topics: Cohort Studies; Ductus Arteriosus, Patent; Gestational Age; Heart Ventricles; Humans; Indomethacin;

2013
Novel treatment criteria for persistent ductus arteriosus in neonates.
    Pediatrics and neonatology, 2014, Volume: 55, Issue:4

    Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Echocardiography; Female; Heart Ventricles; Humans

2014
Variation and comparative effectiveness of patent ductus arteriosus pharmacotherapy in extremely low birth weight infants.
    Journal of neonatal-perinatal medicine, 2014, Jan-01, Volume: 7, Issue:3

    Topics: Cohort Studies; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Ind

2014
Indomethacin-Responsive Patent Ductus Arteriosus in an Extremely Preterm Infant at 8 Weeks Postnatal Age.
    Indian journal of pediatrics, 2015, Volume: 82, Issue:7

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant; Infant, Extremel

2015
Postnatal Steroids and Febrile Seizure Susceptibility in Preterm Children.
    Pediatrics, 2016, Volume: 137, Issue:4

    Topics: Adrenal Cortex Hormones; Child, Preschool; Disease Susceptibility; Epilepsy; Female; Gestational Age

2016
Editorial: Patent Ductus Arteriosus in Extremely Premature Neonates.
    Current pediatric reviews, 2016, Volume: 12, Issue:2

    Topics: Anterior Cerebral Artery; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography, Do

2016
Quality Improvement Initiative to Reduce the Necrotizing Enterocolitis Rate in Premature Infants.
    Pediatrics, 2016, Volume: 137, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Transfusion; Enterocolitis, Necrotizing; Humans; Inci

2016
The effect of ductal diameter on surgical and medical closure of patent ductus arteriosus in preterm neonates.
    The Journal of thoracic and cardiovascular surgery, 2008, Volume: 136, Issue:1

    Topics: Cardiovascular Surgical Procedures; Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus,

2008
Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants.
    American journal of perinatology, 2008, Volume: 25, Issue:8

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; Bronchopulmonary Dysplasia

2008
[Drug therapy of persistent ductus arteriosus Botalli in the premature infant from the nursing viewpoint].
    Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege, 2008, Volume: 27, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Ductus Arteriosus, Patent; Echocardiography

2008
[Neonatal Bartter syndrome's special features in very premature newborns].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2009, Volume: 16, Issue:1

    Topics: Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Bartter Syndrome; Dietary Supplements; Female;

2009
[First SIBEN clinical consensus: diagnostic and therapeutic approach to patent ductus arteriosus in premature newborns].
    Anales de pediatria (Barcelona, Spain : 2003), 2008, Volume: 69, Issue:5

    Topics: Age Factors; Brain Diseases; Cost-Benefit Analysis; Cyclooxygenase Inhibitors; Diuretics; Ductus Art

2008
Early or late surgical ligation of medical refractory patent ductus arteriosus in premature infants.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2009, Volume: 108, Issue:1

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Indomethacin;

2009
Treatment of the patent ductus arteriosus: when, how, and for how long?
    The Journal of pediatrics, 2009, Volume: 155, Issue:6

    Topics: Cyclooxygenase Inhibitors; Drug Administration Schedule; Ductus Arteriosus, Patent; Humans; Indometh

2009
Feeding practices and patent ductus arteriosus ligation preferences-are they related?
    American journal of perinatology, 2010, Volume: 27, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; Ductus Arteriosus, Patent; Enteral Nutrition;

2010
How useful are B-type natriuretic peptide measurements for monitoring changes in patent ductus arteriosus shunt magnitude?
    Journal of perinatology : official journal of the California Perinatal Association, 2010, Volume: 30, Issue:12

    Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Echocardiography; Female; Gestational Age; Humans;

2010
Antenatal magnesium sulfate and the postnatal response of the ductus arteriosus to indomethacin in extremely preterm neonates.
    Journal of perinatology : official journal of the California Perinatal Association, 2011, Volume: 31, Issue:1

    Topics: Drug Administration Schedule; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Gestational Age;

2011
Global shortage and rationing of indomethacin: need to refine approach.
    Journal of perinatology : official journal of the California Perinatal Association, 2010, Volume: 30, Issue:6

    Topics: Ductus Arteriosus, Patent; Global Health; Health Care Rationing; Humans; Indomethacin; Infant, Newbo

2010
Use of echocardiography to guide the duration of indomethacin treatment of patent ductus arteriosus in preterm infants.
    The Journal of pediatrics, 2010, Volume: 157, Issue:2

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography; Gestational Age; Humans; Ind

2010
Comparison of two neonatal indomethacin protocols: efficacy and outcome for patent ductus arteriosus closure.
    Journal of clinical pharmacy and therapeutics, 2010, Volume: 35, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; Ductus Arteriosus, Patent; Female; Gestationa

2010
Urinary aquaporin-2 excretion during ibuprofen or indomethacin treatment in preterm infants with patent ductus arteriosus.
    Acta paediatrica (Oslo, Norway : 1992), 2011, Volume: 100, Issue:1

    Topics: Aquaporin 2; Cardiovascular Agents; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Ibup

2011
Why would a sane clinician not prescribe prophylactic indomethacin?
    Acta paediatrica (Oslo, Norway : 1992), 2011, Volume: 100, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Agents; Clinical Trials as Topic; Ductus Art

2011
Patent ductus arteriosus in the preterm infant: a survey of clinical practices in French neonatal intensive care units.
    Pediatric cardiology, 2011, Volume: 32, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Contraindications; Data Collection; Dose-Response Relations

2011
The risk of necrotizing enterocolitis after indomethacin tocolysis.
    Pediatrics, 2011, Volume: 128, Issue:1

    Topics: Cohort Studies; Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant, Newborn; Infant, P

2011
Indomethacin in pregnancy: applications and safety.
    American journal of perinatology, 2012, Volume: 29, Issue:3

    Topics: Cerclage, Cervical; Cerebral Hemorrhage; Ductus Arteriosus; Enterocolitis, Necrotizing; Female; Fetu

2012
Update on management of patent ductus arteriosus in the preterm infant.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2011, Volume: 24 Suppl 3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin;

2011
Prophylactic indomethacin infusion increases fractional cerebral oxygen extraction in ELBW neonates.
    Journal of perinatology : official journal of the California Perinatal Association, 2012, Volume: 32, Issue:9

    Topics: Brain; Carbon Dioxide; Cerebral Ventricles; Cerebrovascular Circulation; Cyclooxygenase Inhibitors;

2012
Failure of a repeat course of cyclooxygenase inhibitor to close a PDA is a risk factor for developing chronic lung disease in ELBW infants.
    BMC pediatrics, 2012, Jan-27, Volume: 12

    Topics: Chronic Disease; Cyclooxygenase Inhibitors; Drug Administration Schedule; Ductus Arteriosus, Patent;

2012
Patent ductus arteriosus in infants <29 weeks gestation--outcomes and factors affecting closure.
    Indian pediatrics, 2012, Volume: 49, Issue:8

    Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Extremely Pr

2012
Does treatment of patent ductus arteriosus with cyclooxygenase inhibitors affect neonatal regional tissue oxygenation?
    Pediatric cardiology, 2012, Volume: 33, Issue:8

    Topics: Analysis of Variance; Blood Gas Analysis; Cerebrovascular Circulation; Chi-Square Distribution; Chro

2012
Spontaneous intestinal perforation in extremely low birth weight infants: association with indometacin therapy and effects on neurodevelopmental outcomes at 18-22 months corrected age.
    Archives of disease in childhood. Fetal and neonatal edition, 2013, Volume: 98, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Developmental Disabilities; Ductus Arteriosus, Paten

2013
Neurodevelopmental outcomes following two different treatment approaches (early ligation and selective ligation) for patent ductus arteriosus.
    The Journal of pediatrics, 2012, Volume: 161, Issue:6

    Topics: Age Factors; Blindness; Cardiovascular Agents; Cerebral Palsy; Child, Preschool; Combined Modality T

2012
Decline in health status of extremely premature neonates with patent ductus arteriosus after second course of medical therapy.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2013, Volume: 23, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiac Surgical Procedures; Ductus Arteriosus, Patent; Hea

2013
Effectiveness and safety of indomethacin versus ibuprofen for the treatment of patent ductus arteriosus in preterm infants.
    American journal of perinatology, 2013, Volume: 30, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Fema

2013
Change in cognitive function over time in very low-birth-weight infants.
    JAMA, 2003, Feb-12, Volume: 289, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Brain Damage, Chronic; Cerebral Hemorrhage; Child; Child, P

2003
Safety and efficacy of ibuprofen versus indomethacin in preterm infants.
    European journal of pediatrics, 2003, Volume: 162, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, P

2003
Persistent Doppler flow predicts lack of response to multiple courses of indomethacin in premature infants with recurrent patent ductus arteriosus.
    Pediatrics, 2003, Volume: 112, Issue:3 Pt 1

    Topics: Ductus Arteriosus, Patent; Echocardiography, Doppler, Color; Hemodynamics; Humans; Indomethacin; Inf

2003
Indomethacin responsiveness of patent ductus arteriosus and renal abnormalities in preterm infants treated with indomethacin.
    The Journal of pediatrics, 2003, Volume: 143, Issue:2

    Topics: Cardiovascular Agents; Chorioamnionitis; Ductus Arteriosus, Patent; Echocardiography, Doppler; Femal

2003
Tolerance to early human milk feeding is not compromised by indomethacin in preterm infants with persistent ductus arteriosus.
    Acta paediatrica (Oslo, Norway : 1992), 2003, Volume: 92, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Enteral Nutrition; Female; Human

2003
Patent ductus arteriosus, indomethacin and necrotizing enterocolitis in very low birth weight infants: a population-based study.
    Journal of pediatric gastroenterology and nutrition, 2005, Volume: 40, Issue:2

    Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Female; Humans; Indome

2005
Is surgical ligation of patent ductus arteriosus necessary? The Western Australian experience of conservative management.
    Archives of disease in childhood. Fetal and neonatal edition, 2005, Volume: 90, Issue:3

    Topics: Cardiovascular Agents; Cause of Death; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; I

2005
Outcome of very low birth weight infants exposed to antenatal indomethacin for tocolysis.
    Journal of perinatology : official journal of the California Perinatal Association, 2005, Volume: 25, Issue:5

    Topics: Cause of Death; Cohort Studies; Critical Care; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing

2005
Urinary ET-1, AVP and sodium in premature infants treated with indomethacin and ibuprofen for patent ductus arteriosus.
    Pediatric nephrology (Berlin, Germany), 2005, Volume: 20, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Cyclooxygenase 2 Inhibitors; Ductus A

2005
Inhaled nitric oxide.
    The New England journal of medicine, 2005, Oct-13, Volume: 353, Issue:15

    Topics: Administration, Inhalation; Anti-Inflammatory Agents, Non-Steroidal; Bronchopulmonary Dysplasia; Dev

2005
New insights into spontaneous intestinal perforation using a national data set: (1) SIP is associated with early indomethacin exposure.
    Journal of perinatology : official journal of the California Perinatal Association, 2006, Volume: 26, Issue:2

    Topics: Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Databases, Factual; E

2006
Effectiveness and side effects of an escalating, stepwise approach to indomethacin treatment for symptomatic patent ductus arteriosus in premature infants below 33 weeks of gestation.
    Pediatrics, 2005, Volume: 116, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Ne

2005
Consequences of delayed surgical closure of patent ductus arteriosus in very premature infants.
    The Annals of thoracic surgery, 2006, Volume: 81, Issue:1

    Topics: Combined Modality Therapy; Ductus Arteriosus, Patent; Enteral Nutrition; Female; Gestational Age; Hu

2006
Prolonged indomethacin exposure is associated with decreased white matter injury detected with magnetic resonance imaging in premature newborns at 24 to 28 weeks' gestation at birth.
    Pediatrics, 2006, Volume: 117, Issue:5

    Topics: Brain; Brain Damage, Chronic; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Gestational Age;

2006
High-dose indomethacin for patent ductus arteriosus closure: how strong is the evidence?
    Pediatrics, 2006, Volume: 117, Issue:5

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Prematu

2006
Concurrent use of indomethacin and dexamethasone increases the risk of spontaneous intestinal perforation in very low birth weight neonates.
    Journal of perinatology : official journal of the California Perinatal Association, 2006, Volume: 26, Issue:8

    Topics: Case-Control Studies; Dexamethasone; Ductus Arteriosus, Patent; Female; Humans; Hypotension; Indomet

2006
Does patent ductus arteriosus affect feed tolerance in preterm neonates?
    Archives of disease in childhood. Fetal and neonatal edition, 2007, Volume: 92, Issue:1

    Topics: Age Factors; Analysis of Variance; Cardiovascular Agents; Ductus Arteriosus, Patent; Enteral Nutriti

2007
Effect of indomethacin on closure of ductus arteriosus in very-low-birthweight neonates.
    Acta paediatrica (Oslo, Norway : 1992), 2006, Volume: 95, Issue:11

    Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Inf

2006
Prevention of necrotizing enterocolitis in preterm infants: a 20-year experience.
    Pediatrics, 2007, Volume: 119, Issue:1

    Topics: Dexamethasone; Enterocolitis, Necrotizing; Feeding Methods; Female; Humans; Indomethacin; Infant, Ex

2007
Gastrointestinal perforation in very low-birthweight infants.
    Pediatrics international : official journal of the Japan Pediatric Society, 2006, Volume: 48, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Enterocolitis, Necrotizing; Female

2006
Indomethacin prophylaxis or expectant treatment of patent ductus arteriosus in extremely low birth weight infants?
    Journal of perinatology : official journal of the California Perinatal Association, 2007, Volume: 27, Issue:3

    Topics: Cerebral Hemorrhage; Comorbidity; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, N

2007
Oral ibuprofen in early curative closure of patent ductus arteriosus in very premature infants.
    American journal of perinatology, 2007, Volume: 24, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Echocardiography, Doppler, Color

2007
Multiple courses of indomethacin and neonatal outcomes in premature infants.
    Pediatric cardiology, 2008, Volume: 29, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Ductus Arteriosus, Patent; Human

2008
A third course of indomethacin.
    Pediatric cardiology, 2008, Volume: 29, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Ne

2008
Indomethacin therapy for patent ductus arteriosus in premature infants.
    Pediatric cardiology, 2008, Volume: 29, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Gestational Age; Humans; Indomet

2008
Spontaneous closure of the patent ductus arteriosus in very low birth weight infants following discharge from the neonatal unit.
    Archives of disease in childhood. Fetal and neonatal edition, 2009, Volume: 94, Issue:1

    Topics: Cardiac Catheterization; Cardiovascular Agents; Ductus Arteriosus, Patent; Electrocardiography; Epid

2009
[Indomethacin for closure of persisting ductus arteriosus in the premature infant].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1981, Volume: 129, Issue:2

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Prost

1981
Evaluation of adverse renal reactions to prolonged indomethacin therapy in preterm infants with persistent ductus arteriosus.
    Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:3-4

    Topics: Blood Volume; Body Weight; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant,

1983
A variant of Bartter's syndrome. Bartter's syndrome associated with hydramnios, prematurity, hypercalciuria and nephrocalcinosis.
    Acta paediatrica Scandinavica, 1984, Volume: 73, Issue:6

    Topics: Bartter Syndrome; Calcium; Child, Preschool; Female; Humans; Hyperaldosteronism; Indomethacin; Infan

1984
Pharmacokinetics and clinical efficacy of indomethacin in premature infants with patent ductus arteriosus.
    International journal of clinical pharmacology research, 1984, Volume: 4, Issue:2

    Topics: Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Disease

1984
Digoxin and indomethacin in preterm infants with PDA.
    The Journal of pediatrics, 1984, Volume: 105, Issue:4

    Topics: Digoxin; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseas

1984
Management of the premature infant with a patent ductus arteriosus.
    Pediatric clinics of North America, 1984, Volume: 31, Issue:6

    Topics: Blood Transfusion; Cardiac Catheterization; Digoxin; Diuresis; Ductus Arteriosus, Patent; Echocardio

1984
Combined noninvasive assessment of the patent ductus arteriosus in the preterm infant before and after indomethacin treatment.
    The American journal of cardiology, 1984, Dec-01, Volume: 54, Issue:10

    Topics: Ductus Arteriosus, Patent; Echocardiography; Humans; Indomethacin; Infant, Newborn; Infant, Prematur

1984
[Efficacy of indomethacin in the closure of patent ductus arteriosus in premature newborn infants with cardiac insufficiency. Analysis of 14 cases].
    Arquivos brasileiros de cardiologia, 1984, Volume: 43, Issue:3

    Topics: Birth Weight; Ductus Arteriosus, Patent; Electrocardiography; Heart Failure; Heart Murmurs; Humans;

1984
[Presumed side effects of indomethacin in 2 premature infants].
    Ugeskrift for laeger, 1983, Jun-20, Volume: 145, Issue:25

    Topics: Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases;

1983
[Pharmacologic treatment of patent ductus arteriosus in premature infants].
    Anales espanoles de pediatria, 1983, Volume: 18, Issue:6

    Topics: Age Factors; Diuresis; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Pre

1983
[Persistent ductus arteriosus in premature infants].
    Ugeskrift for laeger, 1983, Nov-14, Volume: 145, Issue:46

    Topics: Ductus Arteriosus; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Prematu

1983
[Indomethacin treatment of persistent ductus arteriosus in premature infants].
    Ugeskrift for laeger, 1983, Nov-14, Volume: 145, Issue:46

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Respi

1983
[Surgical ligation of patent ductus arteriosus in the very-low-birth-weight premature infant].
    Annales francaises d'anesthesie et de reanimation, 1983, Volume: 2, Issue:4

    Topics: Anesthesia, General; Body Temperature; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Low

1983
Recurrence of symptomatic patent ductus arteriosus in extremely premature infants, treated with indomethacin.
    The Journal of pediatrics, 1984, Volume: 105, Issue:1

    Topics: Ductus Arteriosus, Patent; Echocardiography; Female; Humans; Indomethacin; Infant, Low Birth Weight;

1984
Prolonged bleeding time in preterm infants receiving indomethacin for patent ductus arteriosus.
    The Journal of pediatrics, 1984, Volume: 105, Issue:2

    Topics: Bleeding Time; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Female; Hemorrhage; Humans; Indometha

1984
Patent ductus arteriosus in premature babies.
    British medical journal (Clinical research ed.), 1981, Dec-05, Volume: 283, Issue:6305

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases

1981
[Fetal hydrops following indomethacin administration during pregnancy].
    Nederlands tijdschrift voor geneeskunde, 1983, Jan-01, Volume: 127, Issue:1

    Topics: Adult; Edema; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Male; Mate

1983
[Therapeutic problems with indomethacin in preterm infants with persistent ductus arteriosus].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1983, Volume: 131, Issue:2

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Kidne

1983
Indomethacin treatment in small versus large premature infants with ductus arteriosus. Comparison of plasma indomethacin concentration and clinical response.
    British heart journal, 1983, Volume: 50, Issue:1

    Topics: Birth Weight; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, D

1983
[Closure of persistent ductus arteriosus in premature infants by drug therapy].
    Orvosi hetilap, 1981, Oct-11, Volume: 122, Issue:41

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Inter

1981
Early indomethacin in patent ductus of the very small premature.
    Australian paediatric journal, 1982, Volume: 18, Issue:1

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Infan

1982
Indomethacin and the preterm infant with a patent ductus arteriosus: relationship between plasma concentration and ductus closure.
    Developmental pharmacology and therapeutics, 1982, Volume: 4, Issue:1-2

    Topics: Bacterial Infections; Dose-Response Relationship, Drug; Ductus Arteriosus, Patent; Half-Life; Humans

1982
Parenteral indomethacin for closure of the patent ductus arteriosus. Clinical experience with 67 preterm infants.
    American journal of diseases of children (1960), 1982, Volume: 136, Issue:11

    Topics: Age Factors; Birth Weight; Bronchopulmonary Dysplasia; Cerebral Hemorrhage; Ductus Arteriosus, Paten

1982
[Treatment of patent ductus arteriosus in preterm infants].
    Anales espanoles de pediatria, 1982, Volume: 16, Issue:6

    Topics: Digoxin; Ductus Arteriosus, Patent; Female; Furosemide; Humans; Indomethacin; Infant, Low Birth Weig

1982
Patent ductus arteriosus in premature infants: a review of current management.
    Pediatric cardiology, 1982, Volume: 3, Issue:1

    Topics: Ductus Arteriosus, Patent; Heart Failure; Humans; Indomethacin; Infant, Newborn; Infant, Premature,

1982
[An alternative in the management of patent ductus arteriosus using indomethacin in premature newborn infants].
    Boletin medico del Hospital Infantil de Mexico, 1982, Volume: 39, Issue:8

    Topics: Birth Weight; Ductus Arteriosus, Patent; Gestational Age; Humans; Indomethacin; Infant, Newborn; Inf

1982
[Maternal treatment with indomethacin and severe neonatal pulmonary hypertension (author's transl)].
    Archives francaises de pediatrie, 1981, Volume: 38, Issue:4

    Topics: Female; Humans; Hypertension, Pulmonary; Indomethacin; Infant, Newborn; Infant, Premature, Diseases;

1981
Serum indomethacin concentrations after intravenous administration to preterm infants with patent ductus arteriosus.
    Acta paediatrica Scandinavica, 1981, Volume: 70, Issue:5

    Topics: Ductus Arteriosus, Patent; Half-Life; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Dise

1981
Gastrointestinal perforation following indomethacin therapy in very low birth weight infants.
    Journal of pediatric surgery, 1981, Volume: 16, Issue:6

    Topics: Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Disease

1981
A comparison of oral and intravenous indomethacin dispositions in the premature infant with patent ductus arteriosus.
    Pediatric pharmacology (New York, N.Y.), 1981, Volume: 1, Issue:3

    Topics: Administration, Oral; Biological Availability; Ductus Arteriosus, Patent; Humans; Indomethacin; Infa

1981
Inulin clearance in the premature infant receiving indomethacin.
    The Journal of pediatrics, 1980, Volume: 96, Issue:4

    Topics: Ductus Arteriosus, Patent; Glomerular Filtration Rate; Humans; Indomethacin; Infant, Newborn; Infant

1980
[Salt and water retention after the administration of indomethacin to premature infants].
    La Nouvelle presse medicale, 1980, Feb-09, Volume: 9, Issue:7

    Topics: Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Male; Water-Electrolyte Imbalanc

1980
Plasma indomethacin levels in preterm newborns with symptomatic patent ductus arteriosus: clinical and echocardiographic assessments of response.
    Advances in prostaglandin and thromboxane research, 1980, Volume: 7

    Topics: Ductus Arteriosus, Patent; Echocardiography; Humans; Indomethacin; Infant, Newborn; Infant, Prematur

1980
Gastric perforation associated with indomethacin therapy in a pre-term infant.
    Australian paediatric journal, 1980, Volume: 16, Issue:1

    Topics: Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant,

1980
Effectiveness and pharmacokinetics of indomethacin in premature newborns with patent ductus arteriosus.
    European journal of clinical pharmacology, 1980, Volume: 18, Issue:1

    Topics: Ductus Arteriosus, Patent; Half-Life; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Dise

1980
Pharmacological closure of ductus arteriosus in preterm infants using indomethacin.
    Archives of disease in childhood, 1980, Volume: 55, Issue:4

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant,

1980
Patent ductus arteriosus in preterm infants.
    The Medical journal of Australia, 1980, Aug-23, Volume: 2, Issue:4

    Topics: Ductus Arteriosus, Patent; Heart Failure; Humans; Hyaline Membrane Disease; Indomethacin; Infant, Ne

1980
Use of indomethacin and its relationship to retinopathy of prematurity in very low birthweight infants.
    Archives of disease in childhood, 1980, Volume: 55, Issue:5

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant,

1980
The disposition of indomethacin in preterm babies.
    The Journal of pediatrics, 1980, Volume: 97, Issue:6

    Topics: Age Factors; Ductus Arteriosus, Patent; Female; Half-Life; Humans; Indomethacin; Infant, Newborn; In

1980
Pharmacokinetics of intravenously administered indomethacin in premature infants.
    The Journal of pediatrics, 1980, Volume: 97, Issue:6

    Topics: Double-Blind Method; Ductus Arteriosus, Patent; Half-Life; Humans; Indomethacin; Infant, Newborn; In

1980
Ibuprofen treatment of patent ductus arteriosus.
    Lancet (London, England), 1995, Jul-22, Volume: 346, Issue:8969

    Topics: Brain; Cerebrovascular Circulation; Ductus Arteriosus, Patent; Gestational Age; Humans; Ibuprofen; I

1995
Predicting oliguria following indomethacin for treatment of patent ductus arteriosus.
    American journal of perinatology, 1994, Volume: 11, Issue:3

    Topics: Creatinine; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Dis

1994
Indomethacin as a tocolytic agent: the controversy continues.
    The Journal of pediatrics, 1994, Volume: 124, Issue:5 Pt 1

    Topics: Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Obstetric Labor, Prematu

1994
[Care of a premature infant in indomethacin therapy with an open ductus arteriosus].
    Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege, 1994, Volume: 13, Issue:3

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases

1994
Neonatal complications after the administration of indomethacin for preterm labor.
    The New England journal of medicine, 1993, Nov-25, Volume: 329, Issue:22

    Topics: Cerebral Hemorrhage; Ductus Arteriosus, Patent; Enterocolitis, Pseudomembranous; Female; Fetus; Huma

1993
Tocolysis with indomethacin increases the incidence of necrotizing enterocolitis in the low-birth-weight neonate.
    American journal of obstetrics and gynecology, 1994, Volume: 170, Issue:1 Pt 1

    Topics: Birth Weight; Chi-Square Distribution; Cohort Studies; Enterocolitis, Pseudomembranous; Female; Gest

1994
Optimal management of patent ductus arteriosus in the neonate weighing less than 800 g.
    Journal of pediatric surgery, 1993, Volume: 28, Issue:9

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant,

1993
Indomethacin and apnea of prematurity.
    Critical care medicine, 1993, Volume: 21, Issue:1

    Topics: Aminophylline; Apnea; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, D

1993
Renal failure in two preterm infants: toxic effect of prenatal maternal indomethacin treatment?
    British journal of obstetrics and gynaecology, 1993, Volume: 100, Issue:1

    Topics: Acute Kidney Injury; Adult; Amniocentesis; Cesarean Section; Female; Humans; Indomethacin; Infant, N

1993
Criteria for use of indomethacin injection in neonates.
    Clinical pharmacy, 1993, Volume: 12, Issue:3

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Prematu

1993
Drug induced closure of patent ductus arteriosus.
    Heart (British Cardiac Society), 1996, Volume: 76, Issue:5

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Fetal Diseases; Humans; Indomethacin;

1996
Effects of prophylactic low-dose indomethacin on hemodynamics in very low birth weight infants.
    The Journal of pediatrics, 1998, Volume: 132, Issue:1

    Topics: Analysis of Variance; Blood Flow Velocity; Cerebral Hemorrhage; Cerebrovascular Circulation; Cycloox

1998
Antenatal indomethacin--adverse fetal effects confirmed.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1998, Volume: 38, Issue:1

    Topics: Cerebral Hemorrhage; Ductus Arteriosus, Patent; Female; Fetal Diseases; Humans; Indomethacin; Infant

1998
Surgical ligation of patent ductus arteriosus in very low birth weight infants: is it safe?
    The American surgeon, 1998, Volume: 64, Issue:10

    Topics: Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Disease

1998
Indomethacin tocolysis increases postnatal patent ductus arteriosus severity.
    Pediatrics, 1998, Volume: 102, Issue:5

    Topics: Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant,

1998
The principles and practice of evidence-based neonatology.
    Pediatrics, 1999, Volume: 103, Issue:1 Suppl E

    Topics: Adrenal Cortex Hormones; Evidence-Based Medicine; Humans; Indomethacin; Infant, Newborn; Infant, Pre

1999
Indomethacin-associated bowel perforations: a study of possible risk factors.
    Journal of pediatric surgery, 1999, Volume: 34, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; Case-Control Studies; Female; Humans; Indomet

1999
Adenosine infusion in the management of a micropremi neonate with pulmonary hypertension.
    Indian pediatrics, 1998, Volume: 35, Issue:12

    Topics: Adenosine; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Fatal Outcome; Humans

1998
Incidence and outcome of a 10-fold indomethacin overdose in premature infants.
    The Journal of pediatrics, 1999, Volume: 135, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Bronchopulmonary Dysplasia; Cerebral Hemorrhage; Ductus Art

1999
Indomethacin treatment decreases renal blood flow velocity in human neonates.
    Biology of the neonate, 1999, Volume: 76, Issue:5

    Topics: Birth Weight; Blood Flow Velocity; Creatinine; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent;

1999
Recent indomethacin tocolysis is not associated with neonatal complications in preterm infants.
    American journal of obstetrics and gynecology, 1999, Volume: 181, Issue:5 Pt 1

    Topics: Birth Weight; Case-Control Studies; Delivery, Obstetric; Drug Administration Schedule; Female; Gesta

1999
Links between early adrenal function and respiratory outcome in preterm infants: airway inflammation and patent ductus arteriosus.
    Pediatrics, 2000, Volume: 105, Issue:2

    Topics: Adrenal Insufficiency; Bronchoalveolar Lavage Fluid; Bronchopulmonary Dysplasia; Chronic Disease; Du

2000
Perinatal indomethacin treatment and neonatal complications in preterm infants.
    European journal of pediatrics, 2000, Volume: 159, Issue:3

    Topics: Cerebral Hemorrhage; Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant, Newborn; Infa

2000
Effect of patent ductus arteriosus and indomethacin treatment on serum cardiac troponin T levels in preterm infants with respiratory distress syndrome.
    European journal of pediatrics, 2000, Volume: 159, Issue:4

    Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Pre

2000
In partial defense of prolonged indomethacin therapy for patent ductus arteriosus.
    The Journal of pediatrics, 2000, Volume: 136, Issue:5

    Topics: Cardiovascular Agents; Drug Administration Schedule; Ductus Arteriosus, Patent; Humans; Indomethacin

2000
Ibuprofen and patent ductus arteriosus.
    The New England journal of medicine, 2000, Sep-07, Volume: 343, Issue:10

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newbo

2000
[Patent ductus arteriosus. A common clinical problem in extremely premature infants].
    Lakartidningen, 2000, Dec-06, Volume: 97, Issue:49

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Fluid Therapy; Humans; Incidence; Indomethacin

2000
Ibuprofen versus indomethacin for closure of patent ductus arteriosus.
    The New England journal of medicine, 2001, Feb-08, Volume: 344, Issue:6

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newbo

2001
Diastolic flow velocity of the left pulmonary artery of patent ductus arteriosus in preterm infants.
    Pediatrics international : official journal of the Japan Pediatric Society, 2001, Volume: 43, Issue:2

    Topics: Blood Flow Velocity; Diastole; Ductus Arteriosus, Patent; Echocardiography, Doppler, Pulsed; Female;

2001
Gastroesophageal endoscopic findings and gastrointestinal symptoms in preterm neonates with and without perinatal indomethacin exposure.
    Journal of pediatric gastroenterology and nutrition, 2001, Volume: 32, Issue:2

    Topics: Biopsy; Case-Control Studies; Ductus Arteriosus, Patent; Endoscopy, Gastrointestinal; Enteral Nutrit

2001
Neonatal acute haemorrhagic gastritis and antenatal exposure to indomethacin for tocolysis.
    ANZ journal of surgery, 2001, Volume: 71, Issue:2

    Topics: Adolescent; Fatal Outcome; Female; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Humans; I

2001
Closure of the ductus arteriosus and development of pulmonary branch stenosis in babies of less than 32 weeks gestation.
    Archives of disease in childhood. Fetal and neonatal edition, 2001, Volume: 85, Issue:3

    Topics: Cardiovascular Agents; Disease Progression; Ductus Arteriosus, Patent; Female; Heart Murmurs; Humans

2001
Treating extremely low birthweight infants with prophylactic indomethacin. Evidence for short term benefits only.
    BMJ (Clinical research ed.), 2002, Jan-12, Volume: 324, Issue:7329

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Agents; Cerebral Hemorrhage; Ductus Arterios

2002
[Dopplersonographic findings in neonates with significant persistent ductus arteriosus].
    Zeitschrift fur Geburtshilfe und Neonatologie, 2002, Volume: 206, Issue:2

    Topics: Anterior Cerebral Artery; Ductus Arteriosus, Patent; Echocardiography, Doppler; Echocardiography, Do

2002
Factors associated with permanent closure of the ductus arteriosus: a role for prolonged indomethacin therapy.
    Pediatrics, 2002, Volume: 110, Issue:1 Pt 1

    Topics: Cardiovascular Agents; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedul

2002
Radiographic and echocardiographic evaluation of newborns treated with indomethacin for patent ductus arteriosus.
    AJR. American journal of roentgenology, 1978, Volume: 131, Issue:6

    Topics: Diagnostic Errors; Ductus Arteriosus, Patent; Echocardiography; Female; Humans; Indomethacin; Infant

1978
[Treatment of hypoxia caused by a right-lef shunt in a newborn infant (effect of indomethacin associated with distending therapy) (preliminary report)].
    Orvosi hetilap, 1978, Sep-17, Volume: 119, Issue:38

    Topics: Arteriovenous Fistula; Ductus Arteriosus, Patent; Humans; Hypoxia; Indomethacin; Infant, Newborn; In

1978
Pharmacologic treatment of patent ductus arteriosus.
    Advances in cardiology, 1979, Volume: 26

    Topics: Drug Evaluation; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature

1979
Plasma indomethacin levels in preterm newborn infants with symptomatic patent ductus arteriosus--clinical and echocardiographic assessments of response.
    The Journal of pediatrics, 1979, Volume: 95, Issue:4

    Topics: Ductus Arteriosus, Patent; Echocardiography; Humans; Indomethacin; Infant, Newborn; Infant, Prematur

1979
Indomethacin and renal function in premature infants with persistent patent ductus arteriosus.
    The Journal of pediatrics, 1979, Volume: 95, Issue:4

    Topics: Ductus Arteriosus, Patent; Glomerular Filtration Rate; Humans; Indomethacin; Infant, Newborn; Infant

1979
[Closure of the ductus arteriosus by medication in low birth weight infants].
    Orvosi hetilap, 1979, Oct-28, Volume: 120, Issue:43

    Topics: Autopsy; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Low Birth Weight; Infant, Newborn;

1979
Perinatal hazards of chronic antenatal tocolysis with indomethacin.
    Prostaglandins, 1979, Volume: 18, Issue:6

    Topics: Adult; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Obstetric Labor,

1979
Medical treatment of the ductus arteriosus.
    Hospital practice, 1977, Volume: 12, Issue:2

    Topics: Animals; Aspirin; Coronary Circulation; Ductus Arteriosus; Ductus Arteriosus, Patent; Fetal Heart; F

1977
Management of premature infants with patent ductus arteriosus.
    The Western journal of medicine, 1978, Volume: 128, Issue:3

    Topics: Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Disease

1978
Urinary excretion of prostaglandin E following the administration of furosemide and indomethacin to sick low-birth-weight infants.
    The Journal of pediatrics, 1978, Volume: 93, Issue:3

    Topics: Calcium; Drug Antagonism; Ductus Arteriosus, Patent; Female; Furosemide; Humans; Hyaline Membrane Di

1978
Problem of patent ductus arteriosus in premature infants.
    Paediatrician, 1978, Volume: 7, Issue:1-3

    Topics: Animals; Aspirin; Blood Pressure; Coronary Circulation; Ductus Arteriosus, Patent; Heart Failure; He

1978
Operation or indomethacin for the premature ductus.
    The Annals of thoracic surgery, 1978, Volume: 26, Issue:6

    Topics: Age Factors; Ductus Arteriosus, Patent; Follow-Up Studies; Humans; Indomethacin; Infant; Infant, New

1978
Pharmacologic closure of patent ductus arteriosus in the premature infant.
    The New England journal of medicine, 1976, Sep-02, Volume: 295, Issue:10

    Topics: Cyclooxygenase Inhibitors; Depression, Chemical; Drug Evaluation; Ductus Arteriosus, Patent; Female;

1976
Commentary: new thoughts on an old problem--patent ductus arteriosus in the premature infant.
    The Journal of pediatrics, 1977, Volume: 90, Issue:2

    Topics: Dose-Response Relationship, Drug; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn;

1977
Closure of the ductus arteriosus in premature infants by inhibition of prostaglandin synthesis.
    The New England journal of medicine, 1976, Sep-02, Volume: 295, Issue:10

    Topics: Aspirin; Depression, Chemical; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Follow-Up Studi

1976
Editorial: Patent ductus revisited.
    The New England journal of medicine, 1976, Sep-02, Volume: 295, Issue:10

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant; Infant, Newborn; Infant, Premature, Disease

1976
Preterm infants with patent ductus arteriosus: treatment with an enteral preparation of indomethacin.
    Annals of tropical paediatrics, 1992, Volume: 12, Issue:4

    Topics: Administration, Oral; Ductus Arteriosus, Patent; Enteral Nutrition; Humans; Indomethacin; Infant, Ne

1992
Atrial natriuretic peptide in the diagnosis of patent ductus arteriosus.
    Acta paediatrica (Oslo, Norway : 1992), 1992, Volume: 81, Issue:9

    Topics: Atrial Natriuretic Factor; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn;

1992
Regional cerebral blood flow velocity changes after indomethacin infusion in preterm infants.
    Archives of disease in childhood, 1992, Volume: 67, Issue:7 Spec No

    Topics: Blood Flow Velocity; Cerebrovascular Circulation; Ductus Arteriosus, Patent; Echocardiography, Doppl

1992
Therapy of symptomatic patent ductus arteriosus in preterms using mefenemic acid and indomethacin.
    Indian pediatrics, 1992, Volume: 29, Issue:3

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Mefen

1992
Day case ligation of patent ductus arteriosus in preterm infants: a 10 year review.
    Archives of disease in childhood, 1991, Volume: 66, Issue:4

    Topics: Birth Weight; Ductus Arteriosus, Patent; Gestational Age; Humans; Indomethacin; Infant, Newborn; Inf

1991
Indomethacin therapy for intraventricular hemorrhage in neonates: another use for that "old" drug.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:12

    Topics: Cerebral Hemorrhage; Cerebral Ventricles; Humans; Indomethacin; Infant, Newborn; Infant, Premature;

1991
Cerebral lesions in preterm infants after tocolytic indomethacin.
    Developmental medicine and child neurology, 1990, Volume: 32, Issue:10

    Topics: Administration, Rectal; Brain; Brain Damage, Chronic; Cerebral Hemorrhage; Dose-Response Relationshi

1990
Asymmetrical pulmonary changes in premature infants with surgical closure of a persistent ductus arteriosus.
    The British journal of radiology, 1990, Volume: 63, Issue:745

    Topics: Bronchopulmonary Dysplasia; Ductus Arteriosus, Patent; Humans; Hyaline Membrane Disease; Indomethaci

1990
Neonatal renal dysfunction and intrauterine exposure to prostaglandin synthesis inhibitors.
    European journal of pediatrics, 1989, Volume: 148, Issue:4

    Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Cesarean Section; Cyclo

1989
Pharmacokinetics of intra-arterial indomethacin treatment for patent ductus arteriosus.
    European journal of pediatrics, 1989, Volume: 149, Issue:2

    Topics: Ductus Arteriosus, Patent; Echocardiography; Female; Humans; Indomethacin; Infant, Newborn; Infant,

1989
Does the respiratory distress syndrome in twins and singletons run different risks of persistent ductus arteriosus?
    Acta geneticae medicae et gemellologiae, 1989, Volume: 38, Issue:3-4

    Topics: Diseases in Twins; Ductus Arteriosus, Patent; Echocardiography; Humans; Indomethacin; Infant, Low Bi

1989
Prostaglandin E2 in the lung lavage fluid of premature newborns before and after surgical or medical closure of a patent ductus arteriosus.
    Biochimica et biophysica acta, 1989, May-15, Volume: 1003, Issue:1

    Topics: Bronchoalveolar Lavage Fluid; Dinoprostone; Ductus Arteriosus, Patent; Female; Humans; Indomethacin;

1989
Localized intestinal perforation following intravenous indomethacin in premature infants.
    Journal of pediatric surgery, 1989, Volume: 24, Issue:4

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Intes

1989
[Indomethacin or ligation in the treatment of persistent ductus arteriosus: a report of clinical experiences].
    Padiatrie und Padologie, 1989, Volume: 24, Issue:2

    Topics: Dose-Response Relationship, Drug; Ductus Arteriosus, Patent; Follow-Up Studies; Humans; Indomethacin

1989
Indomethacin therapy in premature infants with patent ductus arteriosus--determination of therapeutic plasma levels.
    Developmental pharmacology and therapeutics, 1989, Volume: 12, Issue:4

    Topics: Ductus Arteriosus, Patent; Half-Life; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Dise

1989
Preterm labor: its diagnosis and management.
    American journal of obstetrics and gynecology, 1986, Volume: 154, Issue:1

    Topics: Adolescent; Adrenergic beta-Agonists; Adult; Female; Fluid Therapy; Humans; Indomethacin; Infant, Ne

1986
Sepsis and indomethacin failure in premature infants with symptomatic patent ductus arteriosus.
    Lancet (London, England), 1987, Apr-25, Volume: 1, Issue:8539

    Topics: Bacterial Infections; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Prem

1987
Effect of infusion rate of indomethacin on cerebrovascular responses in preterm neonates.
    Archives of disease in childhood, 1989, Volume: 64, Issue:1 Spec No

    Topics: Blood Flow Velocity; Brain; Cerebrovascular Circulation; Drug Administration Schedule; Ductus Arteri

1989
Tolerance of intravenous indomethacin treatment for premature infants with patent ductus arteriosus.
    BMJ (Clinical research ed.), 1988, Sep-24, Volume: 297, Issue:6651

    Topics: Drug Tolerance; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature,

1988
Symptomatic patent ductus arteriosus in premature infants.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1988, Volume: 41, Issue:3

    Topics: Cross-Sectional Studies; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Low Birth

1988
Late closure of the ductus arteriosus using indomethacin in the preterm infant.
    Clinical pediatrics, 1988, Volume: 27, Issue:3

    Topics: Ductus Arteriosus, Patent; Echocardiography; Female; Humans; Indomethacin; Infant, Newborn; Infant,

1988
Indomethacin and cerebral blood flow in premature infants treated for patent ductus arteriosus.
    European journal of pediatrics, 1988, Volume: 147, Issue:3

    Topics: Cerebrovascular Circulation; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infan

1988
[Disorders of kidney function and acute kidney failure in newborn infants].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1987, Volume: 135, Issue:1

    Topics: Acid-Base Equilibrium; Acute Kidney Injury; Aminoglycosides; Anti-Bacterial Agents; Creatinine; Diag

1987
Prolonged indomethacin treatment in preterm infants with symptomatic patent ductus arteriosus: efficacy, drug level monitoring, and patient selection.
    European journal of pediatrics, 1987, Volume: 146, Issue:2

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Monit

1987
[The significance of renal prostaglandins for kidney function in early childhood].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1987, Volume: 135, Issue:4

    Topics: Angiotensin II; Aspirin; Child, Preschool; Creatinine; Ductus Arteriosus, Patent; Glomerular Filtrat

1987
Periventricular haemorrhage: association with patent ductus arteriosus and its treatment with indomethacin or surgery.
    Australian paediatric journal, 1987, Volume: 23, Issue:1

    Topics: Cerebral Hemorrhage; Cerebral Ventricles; Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, N

1987
Symptomatic patent ductus arteriosus in premature neonates: a 5 year study in Toa Payoh Hospital.
    The Journal of the Singapore Paediatric Society, 1987, Volume: 29 Suppl 1

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Respi

1987
Effect of a modified fluid therapy on renal function during indomethacin therapy for persistent ductus arteriosus.
    Acta paediatrica Scandinavica, 1987, Volume: 76, Issue:5

    Topics: Creatinine; Fluid Therapy; Glomerular Filtration Rate; Humans; Indomethacin; Infant; Infant, Newborn

1987
[Treatment with intravenous indomethacin of symptomatic ductus arteriosus in premature newborn infants].
    Anales espanoles de pediatria, 1987, Volume: 27, Issue:2

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Injec

1987
The effect of indomethacin on cerebral blood-flow velocity in premature infants.
    Developmental medicine and child neurology, 1987, Volume: 29, Issue:6

    Topics: Blood Flow Velocity; Cerebrovascular Circulation; Ductus Arteriosus, Patent; Humans; Indomethacin; I

1987
Obstetric management of the very low birth weight fetus.
    Clinics in perinatology, 1986, Volume: 13, Issue:2

    Topics: Adrenal Cortex Hormones; Extraction, Obstetrical; Female; Fetal Distress; Fetal Monitoring; Fetal Or

1986
The management of symptomatic patient ductus arteriosus in premature infants.
    The Journal of the Singapore Paediatric Society, 1986, Volume: 28, Issue:1-2

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant,

1986
Pharmacological manipulation of the ductus arteriosus.
    Archives of disease in childhood, 1986, Volume: 61, Issue:9

    Topics: Drug Administration Schedule; Ductus Arteriosus; Ductus Arteriosus, Patent; Heart Defects, Congenita

1986
[Peculiarities of drug therapy in childhood].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1986, Volume: 134, Issue:11

    Topics: Apnea; Biological Availability; Biotransformation; Caffeine; Child; Child, Preschool; Dexamethasone;

1986
Response of the patent ductus arteriosus to indomethacin treatment.
    American journal of diseases of children (1960), 1987, Volume: 141, Issue:3

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases

1987
Response of the patent ductus arteriosus to indomethacin treatment.
    American journal of diseases of children (1960), 1987, Volume: 141, Issue:3

    Topics: Drug Evaluation; Ductus Arteriosus, Patent; Echocardiography; Female; Humans; Indomethacin; Infant,

1987
Indomethacin therapy in premature infants with patent ductus arteriosus and oliguria.
    Developmental pharmacology and therapeutics, 1986, Volume: 9, Issue:6

    Topics: Anuria; Drug Therapy, Combination; Ductus Arteriosus, Patent; Furosemide; Humans; Indomethacin; Infa

1986
Possible indomethacin-aminoglycoside interaction in preterm infants.
    The Journal of pediatrics, 1985, Volume: 106, Issue:3

    Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Creatinine; Diuresis; Drug Interactions; Ductus Ar

1985
Intestinal perforation associated with indomethacin treatment in premature infants.
    European journal of pediatrics, 1985, Volume: 143, Issue:3

    Topics: Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Low Birth Weight; Infant, Newborn;

1985
Indomethacin therapy of patent ductus in preterm infants controlled by plasma levels.
    Australian paediatric journal, 1985, Volume: 21, Issue:3

    Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases

1985