indomethacin has been researched along with Hypotension, Postural in 35 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a patient with Shy-Drager syndrome the severe episodic diarrhea and orthostatic hypotension were both successfully treated with indomethacin." | 7.66 | [Successful indomethacin therapy of severe diarrhea with primary orthostatic hypotension]. ( Scheidegger, K; Schlup, P; Straub, PW, 1980) |
| "Treatment with indomethacin (75-150 mg/day) raised the upright blood-pressure (B." | 5.26 | Treatment of idiopathic orthostatic hypotension (Shy-Drager syndrome) with indomethacin. ( Itskovitz, HD; Kochar, MS, 1978) |
| "In a patient with Shy-Drager syndrome the severe episodic diarrhea and orthostatic hypotension were both successfully treated with indomethacin." | 3.66 | [Successful indomethacin therapy of severe diarrhea with primary orthostatic hypotension]. ( Scheidegger, K; Schlup, P; Straub, PW, 1980) |
| "Orthostatic hypotension is the most disabling symptom of autonomic failure." | 2.69 | Contrasting actions of pressor agents in severe autonomic failure. ( Biaggioni, I; Black, BK; Jordan, J; Norman, R; Robertson, D; Shannon, JR, 1998) |
| "Postural hypotension is defined as a reduction of at least 20 mm Hg in systolic blood pressure or at least a 10 mm Hg decrease in diastolic blood pressure." | 2.41 | Management of postural hypotension. ( Kochar, MS, 2000) |
| "Fludrocortisone was shown to prevent the orthostatic drop in blood pressure." | 2.39 | Orthostatic hypotension in patients, bed rest subjects, and astronauts. ( Charles, JB; Lathers, CM, 1994) |
| "Orthostatic hypotension is a serious condition that is sometimes manifested in astronauts during standing postflight." | 1.31 | Indomethacin attenuates post-suspension hypotension in Sprague-Dawley rats. ( Bayorh, MA; Eatman, D; Emmett, N; Socci, RR; Thierry-Palmer, M; Wang, M, 2001) |
| "All medications suitable for treating orthostatic hypotension can appreciably increase the blood pressure in the prone patient." | 1.31 | [Effective "home remedies" in orthostatic hypotension. A glass of water before getting up and a brick under the bed]. ( Jordan, J, 2002) |
| "In patients with orthostatic hypotension and central nervous system involvement indomethacin increased recumbent blood pressure, resting forearm vascular resistance, and reflex forearm vasoconstriction during lower body negative pressure." | 1.27 | Increase in reflex vasoconstriction with indomethacin in patients with orthostatic hypotension and central nervous system involvement. ( Ashihara, T; Imaizumi, T; Nakamura, M; Shibazaki, H; Takeshita, A; Tsuji, S, 1984) |
| "1 Indomethacin treatment of postural hypotension in four patients with chronic autonomic failure increased their pressor supersensitivity to intravenous noradrenaline without causing fluid retention." | 1.26 | The pressor actions of noradrenaline and angiotension II in chronic autonomic failure treated with indomethacin. ( Bannister, R; Davies, IB; Hensby, C; Sever, PS, 1980) |
| "Treatment with indomethacin (75-150 mg/day) raised the upright blood-pressure (B." | 1.26 | Treatment of idiopathic orthostatic hypotension (Shy-Drager syndrome) with indomethacin. ( Itskovitz, HD; Kochar, MS, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (80.00) | 18.7374 |
| 1990's | 4 (11.43) | 18.2507 |
| 2000's | 3 (8.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bayorh, MA | 1 |
| Eatman, D | 1 |
| Wang, M | 1 |
| Socci, RR | 1 |
| Emmett, N | 1 |
| Thierry-Palmer, M | 1 |
| Jordan, J | 2 |
| Cruaud, D | 1 |
| Schatz, IJ | 2 |
| Imaizumi, T | 1 |
| Takeshita, A | 1 |
| Ashihara, T | 1 |
| Nakamura, M | 1 |
| Tsuji, S | 1 |
| Shibazaki, H | 1 |
| Awadzi, K | 1 |
| Orme, ML | 1 |
| Breckenridge, AM | 1 |
| Gilles, HM | 1 |
| Crook, JE | 1 |
| Robertson, D | 3 |
| Whorton, AR | 1 |
| Zawada, ET | 1 |
| Galassi, G | 1 |
| Beylot, M | 1 |
| Benzoni, D | 2 |
| Vincent, M | 2 |
| Haro, M | 1 |
| Orgiazzi, J | 1 |
| Noel, G | 1 |
| Castillo, J | 1 |
| Lema, M | 1 |
| García-Martínez, I | 1 |
| Noya, M | 1 |
| Dal Ri, E | 1 |
| Bettini, R | 1 |
| Lovaste, MG | 1 |
| Ferrari, G | 1 |
| Davies, IB | 2 |
| Bannister, R | 2 |
| Sever, PS | 2 |
| Sutcliffe, RL | 1 |
| Levrat, R | 1 |
| Ninet, J | 1 |
| Dano, P | 1 |
| Bouillat, J | 1 |
| Annat, G | 1 |
| Schlup, P | 1 |
| Scheidegger, K | 1 |
| Straub, PW | 1 |
| Jones, DH | 1 |
| Reid, JL | 1 |
| Hensby, C | 1 |
| Lathers, CM | 1 |
| Charles, JB | 1 |
| Shannon, JR | 1 |
| Biaggioni, I | 1 |
| Norman, R | 1 |
| Black, BK | 1 |
| Liaw, LC | 1 |
| Banerjee, K | 1 |
| Coulthard, MG | 1 |
| Kochar, MS | 3 |
| Itskovitz, HD | 2 |
| Abate, G | 1 |
| Polimeni, RM | 1 |
| Cuccurullo, F | 1 |
| Puddu, P | 1 |
| Lenzi, S | 1 |
| Albers, JW | 1 |
| Rumpf, KW | 1 |
| Frenzel, S | 1 |
| Lowitz, HD | 1 |
| Scheler, F | 1 |
| Uchida, K | 1 |
| Himei, H | 1 |
| Hoeldtke, RD | 1 |
| O'Dorisio, TM | 1 |
| Boden, G | 1 |
| Lasaridis, AN | 1 |
| Pitsariotis, B | 1 |
| Syrganis, C | 1 |
| Gatzis, C | 1 |
| Brettou, E | 1 |
| Tourkantonis, A | 1 |
| Thilothammal, N | 1 |
| Dhanaraj, M | 1 |
| Kumaresan, G | 1 |
| Jagannathan, K | 1 |
| Shanmugam, S | 1 |
| Goldberg, MR | 1 |
| FitzGerald, GA | 1 |
| Hinge, HH | 1 |
| Mikkelsen, B | 1 |
| Korsager, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation and Treatment of Autonomic Failure.[NCT00223691] | Phase 1 | 389 participants (Actual) | Interventional | 2002-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for indomethacin and Hypotension, Postural
| Article | Year |
|---|---|
Renal consequences of nonsteroidal antiinflammatory drugs.
Topics: Acidosis; Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Bartter Syndrome; Female; Humans; Hyp | 1982 |
Orthostatic hypotension in patients, bed rest subjects, and astronauts.
Topics: Animals; Atropine; Bed Rest; Female; Fludrocortisone; Humans; Hypotension, Orthostatic; Indomethacin | 1994 |
Management of postural hypotension.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Fludrocortisone; Humans; Hypotension, Orth | 2000 |
5 trials available for indomethacin and Hypotension, Postural
| Article | Year |
|---|---|
The chemotherapy of onchocerciasis VI. The effect of indomethacin and cyproheptadine on the Mazzotti reaction.
Topics: Adult; Clinical Trials as Topic; Cyproheptadine; Diethylcarbamazine; Double-Blind Method; Humans; Hy | 1982 |
Volume expansion and vasodilators in the treatment of idiopathic postural hypotension.
Topics: Aged; Fludrocortisone; Humans; Hydralazine; Hypotension, Orthostatic; Indomethacin; Male; Sodium | 1980 |
Contrasting actions of pressor agents in severe autonomic failure.
Topics: Aged; Autonomic Agents; Blood Pressure; Caffeine; Catecholamines; Female; Heart Rate; Humans; Hypote | 1998 |
Effects of indomethacin on postural hypotension in Parkinsonism.
Topics: Administration, Oral; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypotensi | 1979 |
Treatment of autonomic neuropathy with a somatostatin analogue SMS-201-995.
Topics: Adult; Aged; Autonomic Nervous System Diseases; Blood Pressure; Caffeine; Chronic Disease; Female; H | 1986 |
27 other studies available for indomethacin and Hypotension, Postural
| Article | Year |
|---|---|
Indomethacin attenuates post-suspension hypotension in Sprague-Dawley rats.
Topics: Animals; Baroreflex; Blood Pressure; Cyclooxygenase Inhibitors; Epoprostenol; Head-Down Tilt; Heart | 2001 |
[Effective "home remedies" in orthostatic hypotension. A glass of water before getting up and a brick under the bed].
Topics: Adrenergic alpha-Agonists; Drinking; Humans; Hypotension, Orthostatic; Indomethacin; Medicine, Tradi | 2002 |
[Use of indomethacin in the treatment of orthostatic hypotension in diabetic patients].
Topics: Diabetes Mellitus; Humans; Hypotension, Orthostatic; Indomethacin | 1983 |
Orthostatic hypotension: diagnosis and treatment.
Topics: Blood Pressure; Diagnosis, Differential; Dizziness; Female; Fludrocortisone; Humans; Hypotension, Or | 1984 |
Increase in reflex vasoconstriction with indomethacin in patients with orthostatic hypotension and central nervous system involvement.
Topics: Adult; Aged; Central Nervous System Diseases; Forearm; Hemodynamics; Humans; Hypotension, Orthostati | 1984 |
Prostaglandin suppression: inability to correct severe idiopathic orthostatic hypotension.
Topics: Aged; Blood Pressure; Dose-Response Relationship, Drug; Drug Administration Schedule; Epoprostenol; | 1981 |
Indomethacin and propranolol combined treatment for Shy-Drager syndrome.
Topics: Autonomic Nervous System Diseases; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypote | 1982 |
[Diabetic orthostatic hypotension. Trial of indomethacin therapy].
Topics: Diabetes Complications; Humans; Hypotension, Orthostatic; Indomethacin | 1982 |
[Treatment of chronic idiopathic orthostatic hypotension with indomethacin].
Topics: Chronic Disease; Female; Humans; Hypotension, Orthostatic; Indomethacin; Middle Aged | 1981 |
Study of autonomic functions in primary orthostatic hypotension.
Topics: Autonomic Nervous System Diseases; Blood Pressure; Heart Rate; Humans; Hypotension, Orthostatic; Ind | 1981 |
Indomethacin treatment of postural hypotension in autonomic failure.
Topics: Autonomic Nervous System; Humans; Hypotension, Orthostatic; Indomethacin; Male; Nervous System Disea | 1980 |
Indomethacin treatment of postural hypotension.
Topics: Aged; Flurbiprofen; Humans; Hypotension, Orthostatic; Indomethacin; Prostaglandins E | 1980 |
[Primary orthostatic hypotension. Improvement by indomethacin].
Topics: Aged; Female; Humans; Hypotension, Orthostatic; Indomethacin; Middle Aged | 1980 |
Current management concepts in orthostatic hypotension.
Topics: Fludrocortisone; Humans; Hypotension, Orthostatic; Indomethacin; Monoamine Oxidase Inhibitors; Propr | 1980 |
[Successful indomethacin therapy of severe diarrhea with primary orthostatic hypotension].
Topics: Aged; Diarrhea; Humans; Hypotension, Orthostatic; Indomethacin; Male; Prostatectomy; Urinary Inconti | 1980 |
The pressor actions of noradrenaline and angiotension II in chronic autonomic failure treated with indomethacin.
Topics: Adult; Aged; Angiotensin II; Autonomic Nervous System Diseases; Blood Pressure; Female; Humans; Hypo | 1980 |
Dose related growth response to indometacin in Gitelman syndrome.
Topics: Bartter Syndrome; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Growth Disord | 1999 |
Treatment of idiopathic orthostatic hypotension (Shy-Drager syndrome) with indomethacin.
Topics: Administration, Oral; Blood Pressure; Drug Evaluation; Fecal Incontinence; Female; Follow-Up Studies | 1978 |
Indomethacin for Shy-Drager syndrome.
Topics: Drug Evaluation; Fecal Incontinence; Humans; Hypotension, Orthostatic; Indomethacin; Nervous System | 1978 |
Treatment of orthostatic hypotension with indomethacin.
Topics: Aspirin; Drug Evaluation; Humans; Hypotension, Orthostatic; Indomethacin | 1979 |
[The effect of indomethacin on basal and stimulated plasma renin activity in normal subjects (author's transl)].
Topics: Adult; Basal Metabolism; Blood Pressure; Creatinine; Diuresis; Female; Furosemide; Humans; Hypotensi | 1976 |
[Diabetic orthostatic hypotension].
Topics: Diabetic Neuropathies; Dihydroergotamine; Droxidopa; Humans; Hypotension, Orthostatic; Indomethacin | 1991 |
Severe orthostatic hypotension due to Bartter's syndrome.
Topics: Adult; Bartter Syndrome; Female; Humans; Hyperaldosteronism; Hypotension, Orthostatic; Indomethacin | 1987 |
Treatment of neurogenic orthostatic hypotension with indomethacin.
Topics: Humans; Hypotension, Orthostatic; Indomethacin; Nervous System Diseases | 1986 |
Treatment of neurogenic orthostatic hypotension with indomethacin.
Topics: Humans; Hypotension, Orthostatic; Indomethacin | 1986 |
Prostacyclin biosynthesis and platelet function in autonomic dysfunction.
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Autonomic Nervous System Diseases; Female; Humans; Hypotension, | 1985 |
[Acetylsalicylic acid and indomethacin in the treatment of idiopathic orthostatic hypotension and Shy-Drager's syndrome].
Topics: Aged; Aspirin; Autonomic Nervous System Diseases; Female; Humans; Hypotension, Orthostatic; Indometh | 1985 |