Page last updated: 2024-10-29

indomethacin and Hypoplastic Left Heart Syndrome

indomethacin has been researched along with Hypoplastic Left Heart Syndrome in 2 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Hypoplastic Left Heart Syndrome: A condition caused by underdevelopment of the whole left half of the heart. It is characterized by hypoplasia of the left cardiac chambers (HEART ATRIUM; HEART VENTRICLE), the AORTA, the AORTIC VALVE, and the MITRAL VALVE. Severe symptoms appear in early infancy when DUCTUS ARTERIOSUS closes.

Research Excerpts

ExcerptRelevanceReference
"Close echocardiographic monitoring of fetal Doppler flow velocities is very important after fetal intervention and indomethacin treatment, as the consequences of DA constriction in a fetus with hypoplastic left heart syndrome are potentially lethal."7.76Reversible ductus arteriosus constriction due to maternal indomethacin after fetal intervention for hypoplastic left heart syndrome with intact/restrictive atrial septum. ( Benson, CB; Marshall, AC; McElhinney, DB; Silva, V; Tworetzky, W; Vogel, M; Wilkins-Haug, LE, 2010)
"Close echocardiographic monitoring of fetal Doppler flow velocities is very important after fetal intervention and indomethacin treatment, as the consequences of DA constriction in a fetus with hypoplastic left heart syndrome are potentially lethal."3.76Reversible ductus arteriosus constriction due to maternal indomethacin after fetal intervention for hypoplastic left heart syndrome with intact/restrictive atrial septum. ( Benson, CB; Marshall, AC; McElhinney, DB; Silva, V; Tworetzky, W; Vogel, M; Wilkins-Haug, LE, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Marini, D1
Xu, J1
Sun, L1
Jaeggi, E1
Seed, M1
Vogel, M1
Wilkins-Haug, LE1
McElhinney, DB1
Marshall, AC1
Benson, CB1
Silva, V1
Tworetzky, W1

Reviews

1 review available for indomethacin and Hypoplastic Left Heart Syndrome

ArticleYear
Current and future role of fetal cardiovascular MRI in the setting of fetal cardiac interventions.
    Prenatal diagnosis, 2020, Volume: 40, Issue:1

    Topics: Anemia; Anti-Inflammatory Agents, Non-Steroidal; Atrial Septum; Blood Transfusion, Intrauterine; Duc

2020

Other Studies

1 other study available for indomethacin and Hypoplastic Left Heart Syndrome

ArticleYear
Reversible ductus arteriosus constriction due to maternal indomethacin after fetal intervention for hypoplastic left heart syndrome with intact/restrictive atrial septum.
    Fetal diagnosis and therapy, 2010, Volume: 27, Issue:1

    Topics: Atrial Septum; Catheterization; Constriction, Pathologic; Ductus Arteriosus; Female; Fetal Therapies

2010