indomethacin has been researched along with Hypoplastic Left Heart Syndrome in 2 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Hypoplastic Left Heart Syndrome: A condition caused by underdevelopment of the whole left half of the heart. It is characterized by hypoplasia of the left cardiac chambers (HEART ATRIUM; HEART VENTRICLE), the AORTA, the AORTIC VALVE, and the MITRAL VALVE. Severe symptoms appear in early infancy when DUCTUS ARTERIOSUS closes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Close echocardiographic monitoring of fetal Doppler flow velocities is very important after fetal intervention and indomethacin treatment, as the consequences of DA constriction in a fetus with hypoplastic left heart syndrome are potentially lethal." | 7.76 | Reversible ductus arteriosus constriction due to maternal indomethacin after fetal intervention for hypoplastic left heart syndrome with intact/restrictive atrial septum. ( Benson, CB; Marshall, AC; McElhinney, DB; Silva, V; Tworetzky, W; Vogel, M; Wilkins-Haug, LE, 2010) |
| "Close echocardiographic monitoring of fetal Doppler flow velocities is very important after fetal intervention and indomethacin treatment, as the consequences of DA constriction in a fetus with hypoplastic left heart syndrome are potentially lethal." | 3.76 | Reversible ductus arteriosus constriction due to maternal indomethacin after fetal intervention for hypoplastic left heart syndrome with intact/restrictive atrial septum. ( Benson, CB; Marshall, AC; McElhinney, DB; Silva, V; Tworetzky, W; Vogel, M; Wilkins-Haug, LE, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marini, D | 1 |
| Xu, J | 1 |
| Sun, L | 1 |
| Jaeggi, E | 1 |
| Seed, M | 1 |
| Vogel, M | 1 |
| Wilkins-Haug, LE | 1 |
| McElhinney, DB | 1 |
| Marshall, AC | 1 |
| Benson, CB | 1 |
| Silva, V | 1 |
| Tworetzky, W | 1 |
1 review available for indomethacin and Hypoplastic Left Heart Syndrome
| Article | Year |
|---|---|
Current and future role of fetal cardiovascular MRI in the setting of fetal cardiac interventions.
Topics: Anemia; Anti-Inflammatory Agents, Non-Steroidal; Atrial Septum; Blood Transfusion, Intrauterine; Duc | 2020 |
1 other study available for indomethacin and Hypoplastic Left Heart Syndrome
| Article | Year |
|---|---|
Reversible ductus arteriosus constriction due to maternal indomethacin after fetal intervention for hypoplastic left heart syndrome with intact/restrictive atrial septum.
Topics: Atrial Septum; Catheterization; Constriction, Pathologic; Ductus Arteriosus; Female; Fetal Therapies | 2010 |