indomethacin has been researched along with Hypoglycemia in 13 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effects of an increase in glucose infusion rate of 2 mg/kg per min from the basal infusion rate on the prevention of hypoglycemia in very low-birthweight (VLBW) infants, following indomethacin therapy for patent ductus arteriosus (PDA)." | 7.71 | Preventive management of hypoglycemia in very low-birthweight infants following indomethacin therapy for patent ductus arteriosus. ( Hosono, S; Kimoto, H; Nagoshi, R; Nozawa, M; Ohono, T; Shimizu, M, 2001) |
| "Effects of acute sodium salicylate infusion on glucagon and epinephrine responses to insulin hypoglycemia were studied in streptozotocin diabetic and age-matched control rats." | 7.67 | Effects of acute sodium salicylate on the abnormal counterregulatory glucagon and epinephrine responses to insulin hypoglycemia in diabetic rats. ( Patel, DG, 1989) |
| "To evaluate the effects of an increase in glucose infusion rate of 2 mg/kg per min from the basal infusion rate on the prevention of hypoglycemia in very low-birthweight (VLBW) infants, following indomethacin therapy for patent ductus arteriosus (PDA)." | 3.71 | Preventive management of hypoglycemia in very low-birthweight infants following indomethacin therapy for patent ductus arteriosus. ( Hosono, S; Kimoto, H; Nagoshi, R; Nozawa, M; Ohono, T; Shimizu, M, 2001) |
| "Effects of acute sodium salicylate infusion on glucagon and epinephrine responses to insulin hypoglycemia were studied in streptozotocin diabetic and age-matched control rats." | 3.67 | Effects of acute sodium salicylate on the abnormal counterregulatory glucagon and epinephrine responses to insulin hypoglycemia in diabetic rats. ( Patel, DG, 1989) |
| "The effects of alpha 2-adrenergic-receptor blocker mianserin on the responses of blood glucose, plasma beta-thromboglobulin (beta-TG), and various counterregulatory hormones to insulin-induced hypoglycemia were studied in nine healthy male subjects." | 3.67 | Role of alpha 2-adrenergic receptor in platelet activation during insulin-induced hypoglycemia in normal subjects. ( Fukushima, H; Ichinose, K; Kishikawa, H; Kiyota, S; Matsuda, H; Nakamura, N; Sakakida, M; Takeda, H; Uzawa, H, 1987) |
| "Pretreatment with indomethacin was introduced in order to evaluate the possible influence of fatty acid cyclo-oxygenase products on the pattern of CBF changes." | 1.26 | Cerebrovascular response during and following severe insulin-induced hypoglycemia: CO2-sensitivity, autoregulation, and influence of prostaglandin synthesis inhibition. ( Agardh, CD; Ingvar, M; Nilsson, B; Siesjö, BK, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (53.85) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, Y | 1 |
| Matsuwaki, T | 2 |
| Yamanouchi, K | 2 |
| Nishihara, M | 2 |
| Kayasuga, Y | 1 |
| Siesjö, BK | 3 |
| Nilsson, B | 2 |
| Diwan, PV | 1 |
| Kulkarni, DR | 1 |
| Agardh, CD | 1 |
| Ingvar, M | 1 |
| Rehncrona, S | 1 |
| Smith, D | 1 |
| Hosono, S | 3 |
| Ohno, T | 2 |
| Kimoto, H | 3 |
| Nagoshi, R | 3 |
| Shimizu, M | 3 |
| Nozawa, M | 3 |
| Ojima, K | 1 |
| Ohono, T | 1 |
| Chajek-Shaul, T | 1 |
| Barash, V | 1 |
| Weidenfeld, J | 1 |
| Friedman, G | 1 |
| Ziv, E | 1 |
| Shohami, E | 1 |
| Shiloni, E | 1 |
| Patel, DG | 1 |
| Kishikawa, H | 1 |
| Takeda, H | 1 |
| Kiyota, S | 1 |
| Sakakida, M | 1 |
| Fukushima, H | 1 |
| Ichinose, K | 1 |
| Matsuda, H | 1 |
| Nakamura, N | 1 |
| Uzawa, H | 1 |
| Barlascini, CO | 1 |
| Schmitt, JK | 1 |
1 review available for indomethacin and Hypoglycemia
| Article | Year |
|---|---|
Prostaglandins and the cerebral circulation.
Topics: Animals; Brain; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Dose-Response Relationship, | 1982 |
12 other studies available for indomethacin and Hypoglycemia
| Article | Year |
|---|---|
Cyclooxygenase-2-related signaling in the hypothalamus plays differential roles in response to various acute stresses.
Topics: Adrenalectomy; Animals; Corticotropin-Releasing Hormone; Cyclooxygenase 2; Cyclooxygenase 2 Inhibito | 2013 |
Maintenance of gonadotropin secretion by glucocorticoids under stress conditions through the inhibition of prostaglandin synthesis in the brain.
Topics: Adrenal Glands; Animals; Body Temperature; Brain; Corticosterone; Cyclooxygenase 2; Deoxyglucose; Fe | 2006 |
Influence of non-steroidal anti-inflammatory agents on tolbutamide hypoglycaemia.
Topics: Animals; Anti-Inflammatory Agents; Female; Humans; Hypoglycemia; Ibuprofen; Indomethacin; Male; orth | 1983 |
Cerebrovascular response during and following severe insulin-induced hypoglycemia: CO2-sensitivity, autoregulation, and influence of prostaglandin synthesis inhibition.
Topics: Animals; Brain; Carbon Dioxide; Cerebrovascular Circulation; Glucose; Homeostasis; Hypoglycemia; Ind | 1981 |
Neuronal cell damage in the brain: possible involvement of oxidative mechanisms.
Topics: Animals; Brain Diseases; Brain Ischemia; Cerebrovascular Circulation; Hypoglycemia; Hypoxia; Indomet | 1980 |
Reduction in blood glucose values following indomethacin therapy for patent ductus arteriosus.
Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Female; Humans; Hypoglycemia; Indomethacin; Infant | 1999 |
Intractable hypoglycemia following indomethacin therapy for patent ductus arteriosus.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Humans; Hypoglycemia; In | 2000 |
Preventive management of hypoglycemia in very low-birthweight infants following indomethacin therapy for patent ductus arteriosus.
Topics: Blood Glucose; Ductus Arteriosus, Patent; Female; Gestational Age; Glucose; Humans; Hypoglycemia; In | 2001 |
Lethal hypoglycemia and hypothermia induced by administration of low doses of tumor necrosis factor to adrenalectomized rats.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Blood Glucose; Body Temperature Regulation; Dexamethasone; | 1990 |
Effects of acute sodium salicylate on the abnormal counterregulatory glucagon and epinephrine responses to insulin hypoglycemia in diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Epinephrine; Glucagon; Hypoglycemia; Indomethacin; Insulin | 1989 |
Role of alpha 2-adrenergic receptor in platelet activation during insulin-induced hypoglycemia in normal subjects.
Topics: Adult; beta-Thromboglobulin; Blood Platelets; Epinephrine; Humans; Hypoglycemia; Indomethacin; Insul | 1987 |
Indomethacin, hypoglycemia, quadriplegia.
Topics: Glucagon; Humans; Hypoglycemia; Indomethacin; Quadriplegia | 1987 |