Page last updated: 2024-10-29

indomethacin and Hypocalcemia

indomethacin has been researched along with Hypocalcemia in 9 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Hypocalcemia: Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Treatment with hydrochlorothiazide is effective in patients without increased urinary excretion of prostaglandin, whereas patients with increased prostaglandin excretion respond better to indomethacin therapy."1.27[Clinical variants of idiopathic hypercalciuria in children]. ( Bachmann, H; Kohout, I, 1987)
"When indomethacin (I) was administered to hypocalcemic (VE + I) and normocalcemic (VE + Ca2+ + I) AVE animals, both groups of animals had tubular and whole-kidney chloride reabsorption similar to VE animals."1.27Hypocalcemia-associated modulation of renal response to acute volume expansion in rats. ( Wesson, DE, 1987)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kato, Y1
Senzaki, H1
Ogura, H1
Shemerdiak, WP1
Kukreja, SC1
Johnson, PA1
Walker, PR1
Whitfield, JF1
Mayan, H1
Hourvitz, A1
Schiff, E1
Farfel, Z1
Lien, J1
Kaye, M1
MacManus, JP1
Braceland, BM1
Kohout, I1
Bachmann, H1
Cuneo, R1
Gilchrist, N1
Sainsbury, R1
Wesson, DE1

Other Studies

9 other studies available for indomethacin and Hypocalcemia

ArticleYear
Aspirin-induced hypocalcemia in the rat.
    Toxicology and applied pharmacology, 1982, Jun-15, Volume: 64, Issue:1

    Topics: Adrenalectomy; Animals; Aspirin; Body Weight; Calcium; Hypocalcemia; Indomethacin; Male; Nephrectomy

1982
Effect of prostaglandin E1, E2 or indomethacin on serum parathyroid hormone and calcitonin in the rat.
    Prostaglandins and medicine, 1981, Volume: 6, Issue:6

    Topics: Animals; Calcitonin; Calcium; Hypocalcemia; Indomethacin; Male; Parathyroid Glands; Parathyroid Horm

1981
Regulation of the prereplicative changes in the synthesis and transport of messenger and ribosomal RNA in regenerating livers of normal and hypocalcemic rats.
    Journal of cellular physiology, 1981, Volume: 108, Issue:3

    Topics: Animals; Colchicine; DNA Replication; Hypocalcemia; Indomethacin; Liver Regeneration; Poly A; Rats;

1981
Symptomatic hypocalcaemia in hypermagnesaemia-induced hypoparathyroidism, during magnesium tocolytic therapy--possible involvement of the calcium-sensing receptor.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:7

    Topics: Adult; Calcium; Female; Humans; Hypocalcemia; Hypoparathyroidism; Indomethacin; Magnesium; Nifedipin

1999
Changes in red cell space of bone in hypocalcemic states: studies in rat femur.
    The American journal of physiology, 1978, Volume: 234, Issue:1

    Topics: Animals; Bone and Bones; Calcitonin; Calcium, Dietary; Erythrocytes; Hypocalcemia; Indomethacin; Mal

1978
A connection between the production of prostaglandins during liver regeneration and the DNA synthetic response.
    Prostaglandins, 1976, Volume: 11, Issue:4

    Topics: Animals; Arachidonic Acids; Calcium; DNA; Female; Humans; Hypocalcemia; Indomethacin; Liver; Liver R

1976
[Clinical variants of idiopathic hypercalciuria in children].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1987, Volume: 135, Issue:12

    Topics: Aldosterone; Calcium; Child; Child, Preschool; Dinoprostone; Female; Humans; Hydrochlorothiazide; Hy

1987
Hypocalcaemia and indomethacin.
    The New Zealand medical journal, 1986, Oct-08, Volume: 99, Issue:811

    Topics: Aged; Aged, 80 and over; Humans; Hypocalcemia; Indomethacin; Kidney Diseases; Male

1986
Hypocalcemia-associated modulation of renal response to acute volume expansion in rats.
    The American journal of physiology, 1987, Volume: 253, Issue:4 Pt 2

    Topics: Animals; Blood Volume; Body Water; Glomerular Filtration Rate; Hypocalcemia; Indomethacin; Kidney; P

1987