Page last updated: 2024-10-29

indomethacin and Hyperuricemia

indomethacin has been researched along with Hyperuricemia in 3 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Hyperuricemia: Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.

Research Excerpts

ExcerptRelevanceReference
"Lesinurad is a novel selective uric acid reabsorption inhibitor approved for treatment of hyperuricemia associated with gout in combination with xanthine oxidase inhibitors (XOIs)."3.85Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and Commonly Used Drugs for Gout Treatment. ( Bucci, G; Gillen, M; Kerr, B; Lee, C; Shen, Z; Tieu, K; Wilson, D, 2017)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujii, M1
Takahashi, I1
Kishiyama, K1
Honma, M1
Ishida-Yamamoto, A1
Shen, Z1
Tieu, K1
Wilson, D1
Bucci, G1
Gillen, M1
Lee, C1
Kerr, B1
de Albuquerque Ugoline, BC1
de Souza, J1
Ferrari, FC1
Ferraz-Filha, ZS1
Coelho, GB1
Saúde-Guimarães, DA1

Other Studies

3 other studies available for indomethacin and Hyperuricemia

ArticleYear
Case of generalized eosinophilic pustular folliculitis induced by allopurinol.
    The Journal of dermatology, 2016, Volume: 43, Issue:4

    Topics: Administration, Oral; Aged; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Comb

2016
Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and Commonly Used Drugs for Gout Treatment.
    Clinical pharmacology in drug development, 2017, Volume: 6, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Colchicine; Drug Administration Schedule; Drug Interactions; Female;

2017
The influence of seasonality on the content of goyazensolide and on anti-inflammatory and anti-hyperuricemic effects of the ethanolic extract of Lychnophora passerina (Brazilian arnica).
    Journal of ethnopharmacology, 2017, Feb-23, Volume: 198

    Topics: Animals; Anti-Inflammatory Agents; Asteraceae; Brazil; Bridged-Ring Compounds; Chromatography, High

2017