Page last updated: 2024-10-29

indomethacin and Hypertrophy

indomethacin has been researched along with Hypertrophy in 13 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).

Research Excerpts

ExcerptRelevanceReference
" The results of the present investigation demonstrates a reduction by indomethacin of soleus hypertrophy, which occurred during a one week recovery period following rat hindlimb suspension."4.77Influences of inactivity and indomethacin on soleus phosphatidylethanolamine and size. ( Moss, R; Padalino, M; Templeton, GH, 1986)
"A four-year-old girl with growth failure and clinical and laboratory evidence of Bartter's syndrome responded to indomethacin treatment with decreased urinary prostaglandin excretion, symptomatic and chemical improvement, and accelerated growth."3.67Reversal of Bartter's syndrome by renal transplantation in a child with focal, segmental glomerular sclerosis. ( Blethen, SL; Jennette, JC; Lorentz, WB; Van Wyk, JJ, 1985)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's5 (38.46)18.2507
2000's1 (7.69)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, SO1
Harris, SM1
Duffy, DM1
Belin de Chantemèle, EJ1
Vessières, E1
Guihot, AL1
Toutain, B1
Loufrani, L1
Henrion, D1
van den Hoff, MJ1
Deprez, RH1
Ruijter, JM1
de Boer, PA1
Tesink-Taekema, S1
Buffing, AA1
Lamers, WH1
Moorman, AF1
Osório, JA1
Schunke, A1
Pagnoncelli, CC1
Barbosa, ED1
Baldauf, NJ1
De, S1
Zelazny, ET1
Souhrada, JF1
Souhrada, M1
Mahadevan, P1
Larkins, RG1
Fraser, JR1
Dunlop, ME1
Löhrke, B1
Wegner, J1
Viergutz, T1
Dietl, G1
Ender, K1
Włodarski, K1
Luczak, M1
Galus, R1
Włodarski, P1
Vasadi, P1
Selmeci, L1
Pósch, E1
Hársing, L1
Chaudhuri, G1
Wight, JP1
Bassett, AH1
Le Carpentier, JE1
el Nahas, AM1
Templeton, GH1
Padalino, M1
Moss, R1
Blethen, SL1
Van Wyk, JJ1
Lorentz, WB1
Jennette, JC1

Reviews

1 review available for indomethacin and Hypertrophy

ArticleYear
Influences of inactivity and indomethacin on soleus phosphatidylethanolamine and size.
    Prostaglandins, 1986, Volume: 31, Issue:3

    Topics: Animals; Calcium; Calcium-Transporting ATPases; Fatty Acids; Hypertrophy; Immobilization; Indomethac

1986

Other Studies

12 other studies available for indomethacin and Hypertrophy

ArticleYear
Prostaglandin E2 (EP) receptors mediate PGE2-specific events in ovulation and luteinization within primate ovarian follicles.
    Endocrinology, 2014, Volume: 155, Issue:4

    Topics: Animals; Chorionic Gonadotropin; Cumulus Cells; Dinoprostone; Female; Granulosa Cells; Haplorhini; H

2014
Cyclooxygenase-2 preserves flow-mediated remodelling in old obese Zucker rat mesenteric arteries.
    Cardiovascular research, 2010, Jun-01, Volume: 86, Issue:3

    Topics: Acetylcholine; Age Factors; Animals; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Di

2010
Increased cardiac workload by closure of the ductus arteriosus leads to hypertrophy and apoptosis rather than to hyperplasia in the late fetal period.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Apoptosis; Body Weight; Bromodeox

2004
[Action of indomethacin on renal blood flow and urinary excretion during compensatory hypertrophy].
    Revista brasileira de biologia, 1980, Volume: 40, Issue:3

    Topics: Animals; Hypertrophy; Indomethacin; Kidney; Male; Nephrectomy; Rats; Regional Blood Flow

1980
IL-1 beta and IL-6 induce hyperplasia and hypertrophy of cultured guinea pig airway smooth muscle cells.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:4

    Topics: Animals; DNA; Guinea Pigs; Hyperplasia; Hypertrophy; Indomethacin; Interleukin-1; Interleukin-6; Mal

1995
Effect of prostaglandin E2 and hyaluronan on mesangial cell proliferation. A potential contribution to glomerular hypercellularity in diabetes.
    Diabetes, 1996, Volume: 45, Issue:1

    Topics: Animals; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental;

1996
Flow-cytometric analysis of oxidative and proteolytical activities in tissue-associated phagocytes from normal and hypertrophic muscles.
    Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology, 1995, Volume: 9, Issue:4

    Topics: Animals; Caseins; Cattle; Endopeptidases; Flow Cytometry; Hydrolysis; Hypertrophy; Indomethacin; Mal

1995
Local hypertrophic/hyperplastic changes of keratinizing squamous epithelium of pinna induced by concanavalin A and other immunomodulators in mice.
    Folia biologica, 1999, Volume: 45, Issue:5

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Transplantatio

1999
Hypertrophic response of the kidney in indomethacin treated rats.
    Acta physiologica Academiae Scientiarum Hungaricae, 1979, Volume: 53, Issue:4

    Topics: Animals; Hypertrophy; Indomethacin; Kidney; Male; Organ Size; Rats; Ribonucleases; RNA

1979
Inhibition by aspirin and indomethacin of uterine hypertrophy induced by an IUD.
    Journal of reproduction and fertility, 1975, Volume: 43, Issue:1

    Topics: Animals; Aspirin; Castration; Fallopian Tubes; Female; Hydrocortisone; Hypertrophy; Indomethacin; In

1975
Effect of treatment with enalapril, verapamil and indomethacin on compensatory renal growth in the rat.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1990, Volume: 5, Issue:9

    Topics: Animals; Body Weight; Enalapril; Hypertrophy; Indomethacin; Kidney; Male; Nephrectomy; Organ Size; R

1990
Reversal of Bartter's syndrome by renal transplantation in a child with focal, segmental glomerular sclerosis.
    The American journal of the medical sciences, 1985, Volume: 289, Issue:1

    Topics: Alkalosis; Child, Preschool; Female; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Humans

1985