indomethacin has been researched along with Hypersensitivity in 62 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mechanism of the anti-inflammatory effect of proglumetacin maleate, a novel indomethacin derivative, was examined in vivo in an allergic air pouch inflammation model in rats." | 7.67 | Effects of proglumetacin maleate and its major metabolites on allergic air pouch inflammation in rats. ( Miyake, H; Ono, N; Sunami, A; Yamamoto, N; Yamasaki, Y, 1987) |
| "The effect of indomethacin and dexamethasone on an allergic inflammation in rats, a novel model of allergic inflammation of an air pouch type, was examined." | 7.66 | A possible role of arachidonate metabolism in allergic air pouch inflammation in rats. Anti-inflammatory effect of indomethacin and dexamethasone and the level of prostaglandin E2 in the exudate. ( Kanaoka, K; Levine, L; Ohuchi, K; Tsurufuji, S; Yoshino, S, 1982) |
| "Flurbiprofen was less effective than indomethacin in the immediate hypersensitivity reaction (IHR) model." | 5.27 | In vivo effects of indomethacin and flurbiprofen on the locomotion of neutrophils elicited by immune and non-immune inflammation in the rat. ( Giroud, JP; Hakim, J; Perianin, A; Roch-Arveiller, M, 1984) |
| "The analgesic effects on pain-related behaviors following the topical application of hangeshashinto were evaluated in an oral ulcer rat model treated with acetic acid using recently developed methods." | 3.83 | The traditional Japanese medicine hangeshashinto alleviates oral ulcer-induced pain in a rat model. ( Hattori, T; Hitomi, S; Imai, R; Inenaga, K; Kase, Y; Kubota, K; Omiya, Y; Ono, K; Terawaki, K; Yamaguchi, K, 2016) |
| " The anti- oedema effect was compared with indomethacin." | 3.76 | Immunomodulatory, analgesic and antipyretic effects of violacein isolated from Chromobacterium violaceum. ( Antonisamy, P; Ignacimuthu, S, 2010) |
| "Using an experimental model for allergic inflammation of the air pouch type in rats, the effects of dexamethasone and indomethacin on leukocyte infiltration and level of chemotactic activity in the inflammatory exudate were examined to clarify the mechanisms of anti-inflammatory effects of glucocorticoids." | 3.67 | Reduction by dexamethasone of chemotactic activity in inflammatory exudates. ( Kurihara, A; Ohuchi, K; Tsurufuji, S, 1984) |
| " Furthermore, the complete reversal of indomethacin potentiation of allergic inflammation by addition of PGE2 in low concentration advocates a regulatory function of the endogenous and locally formed PGE2." | 3.67 | Dual action of prostaglandin E2 in allergic inflammation. ( Dahlén, SE; Hedqvist, P; Raud, J, 1989) |
| "The mechanism of the anti-inflammatory effect of proglumetacin maleate, a novel indomethacin derivative, was examined in vivo in an allergic air pouch inflammation model in rats." | 3.67 | Effects of proglumetacin maleate and its major metabolites on allergic air pouch inflammation in rats. ( Miyake, H; Ono, N; Sunami, A; Yamamoto, N; Yamasaki, Y, 1987) |
| " The pharmacologic characteristics of the antigen-induced airway smooth muscle contraction in vitro were similar to those induced by arachidonic acid and the leukotrienes only in some respects but were clearly different from those induced by compound 48/80." | 3.67 | Pharmacological characterization of airway smooth muscle responses to antigen in ascaris-sensitive dogs. ( Davis, C; Kannan, L; Kannan, MS; Ladenius, AR; Sankaranarayanan, A, 1986) |
| " To explore a possible therapeutic application of substances that inhibit 15-LO of soybean in vitro, we have tested several active compounds, namely nordihydroguaiaretic acid (NDGA), phenidone, diethylcarbamazine and mefenamic acid, on the following in vivo inflammation models in the rat: plantar oedema induced by carrageenin; cutaneous vascular hyperpermeability induced by pafacether; pleurisy induced by carrageenin." | 3.67 | In vivo anti-allergic and anti-inflammatory effects of drugs that inhibit lipoxygenase activity in vitro. ( Braquet, P; Clostre, F; Etienne, A; Soulard, C; Touvay, C, 1985) |
| " An analogous mechanism may account for aspirin-induced asthma in man." | 3.66 | Evidence for lipoxygenase pathway involvement in allergic tracheal contraction. ( Burka, JF; Paterson, NA, 1980) |
| "The effect of indomethacin and dexamethasone on an allergic inflammation in rats, a novel model of allergic inflammation of an air pouch type, was examined." | 3.66 | A possible role of arachidonate metabolism in allergic air pouch inflammation in rats. Anti-inflammatory effect of indomethacin and dexamethasone and the level of prostaglandin E2 in the exudate. ( Kanaoka, K; Levine, L; Ohuchi, K; Tsurufuji, S; Yoshino, S, 1982) |
| "Experimental allergic myocarditis was induced in rabbits; a study was made of the effect on the kininogen content and on the activity of kininase in the myocardium, and on its morphological structure produced by anginine, contrical, aspirin, indometacine and epsilon-aminocapronic acid." | 3.65 | [Changes in the kinin system components and structure of the myocardium under the influence of antikinin preparations in allergic myocarditis in rabbits]. ( Gurevich, MA; Iankovskaia, MO; Odinokova, VA; Paleev, NR; Surovikina, MS, 1976) |
| "Acute and chronic sialoadenitis were induced in ovalbumin-immunized guinea pigs by a single or repeated (once a day for 5 days) instillation of antigen into the parotid gland via the parotid duct." | 1.28 | Experimental models of acute and chronic sialoadenitis in the guinea pig. ( Aonuma, S; Mikami, T; Miyasaka, K; Miyazawa, K, 1992) |
| " L-Serine borate (45 mM), an inhibitor of gamma-glutamyl transpeptidase, shifted the dose-response curve of LTC4 to the left by 161-fold, and L-cysteine (6 mM), an inhibitor of aminopeptidase, shifted the dose-response curves of LTC4 and LTD4 to the left by 67- and 23-fold, respectively." | 1.28 | Characterization of sulfidopeptide leukotriene responses in sheep tracheal smooth muscle in vitro. ( Abraham, WM; Jackowski, JT; Tomioka, K, 1991) |
| " Dose-response lines in response to the two agonists, expressed as percent maximal contraction, did not differ among the groups." | 1.28 | Muscarinic-receptor functioning in tracheas from normal and ovalbumin-sensitive guinea pigs. ( Biggs, DF; Yang, ZJ, 1991) |
| "Flurbiprofen was less effective than indomethacin in the immediate hypersensitivity reaction (IHR) model." | 1.27 | In vivo effects of indomethacin and flurbiprofen on the locomotion of neutrophils elicited by immune and non-immune inflammation in the rat. ( Giroud, JP; Hakim, J; Perianin, A; Roch-Arveiller, M, 1984) |
| "Indomethacin pretreatment attenuated the antigen-induced increase in Qbr, thus suggesting that vasodilator cyclooxygenase products contribute to the vascular response." | 1.27 | Modification of bronchial blood flow during allergic airway responses. ( Abraham, WM; Codias, E; Long, WM; Martinez, H; Sprung, CL; Wanner, A; Yerger, LD, 1988) |
| "Diffuse cutaneous leishmaniasis is characterized by multiple nonulcerative skin lesions." | 1.26 | Specific inhibition of lymphocyte-proliferation responses by adherent suppressor cells in diffuse cutaneous leishmaniasis. ( Bogaert Diaz, H; Neva, FA; Oster, CN; Petersen, EA, 1982) |
| "Prevention of arterial hypoxemia by oxygen breathing blocked an increase in pulmonary vascular resistance in four pretreated responders." | 1.26 | Failure of hypoxic pulmonary vasoconstriction in the canine asthma model. Effect of prostaglandin inhibitors. ( Baier, H; Cohn, MA; Wanner, A, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (66.13) | 18.7374 |
| 1990's | 8 (12.90) | 18.2507 |
| 2000's | 6 (9.68) | 29.6817 |
| 2010's | 7 (11.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hata, AN | 1 |
| Lybrand, TP | 1 |
| Breyer, RM | 1 |
| Riley, JP | 1 |
| Fuchs, B | 1 |
| Sjöberg, L | 1 |
| Nilsson, GP | 1 |
| Karlsson, L | 1 |
| Dahlén, SE | 2 |
| Rao, NL | 1 |
| Adner, M | 1 |
| Zhou, W | 3 |
| Goleniewska, K | 3 |
| Zhang, J | 2 |
| Dulek, DE | 2 |
| Toki, S | 2 |
| Lotz, MT | 1 |
| Newcomb, DC | 2 |
| Boswell, MG | 1 |
| Polosukhin, VV | 1 |
| Milne, GL | 1 |
| Wu, P | 2 |
| Moore, ML | 1 |
| FitzGerald, GA | 1 |
| Peebles, RS | 4 |
| Hitomi, S | 1 |
| Ono, K | 1 |
| Yamaguchi, K | 1 |
| Terawaki, K | 1 |
| Imai, R | 1 |
| Kubota, K | 1 |
| Omiya, Y | 1 |
| Hattori, T | 1 |
| Kase, Y | 1 |
| Inenaga, K | 1 |
| Cephus, JY | 1 |
| Collins, RD | 3 |
| Boothby, MR | 1 |
| Antonisamy, P | 1 |
| Ignacimuthu, S | 1 |
| Rievaj, J | 1 |
| Davidson, C | 1 |
| Nadeem, A | 1 |
| Hollenberg, M | 1 |
| Duszyk, M | 1 |
| Vliagoftis, H | 1 |
| Scott, NM | 1 |
| Ng, RL | 1 |
| Strickland, DH | 1 |
| Bisley, JL | 1 |
| Bazely, SA | 1 |
| Gorman, S | 1 |
| Norval, M | 1 |
| Hart, PH | 1 |
| Hashimoto, K | 1 |
| Sheller, JR | 2 |
| Morrow, JD | 1 |
| O'Neal, J | 1 |
| Ji, S | 1 |
| Mitchell, DB | 2 |
| Graham, BS | 2 |
| Garfield, RE | 1 |
| Irani, AM | 1 |
| Schwartz, LB | 1 |
| Bytautiene, E | 1 |
| Romero, R | 1 |
| Rahman, A | 1 |
| Yatsuzuka, R | 1 |
| Jiang, S | 1 |
| Ueda, Y | 1 |
| Kamei, C | 1 |
| Kuraishi, Y | 1 |
| Ohtsuka, E | 1 |
| Nakano, T | 1 |
| Kawai, S | 1 |
| Andoh, T | 1 |
| Nojima, H | 1 |
| Kamimura, K | 1 |
| Malo, PE | 1 |
| Wasserman, MA | 1 |
| Wojnar, RJ | 1 |
| Hearn, T | 1 |
| Starkweather, S | 1 |
| DeShazo, RD | 1 |
| Levinson, AI | 1 |
| Dvorak, HF | 1 |
| Ohuchi, K | 5 |
| Watanabe, M | 2 |
| Levine, L | 2 |
| Petersen, EA | 1 |
| Neva, FA | 1 |
| Oster, CN | 1 |
| Bogaert Diaz, H | 1 |
| Perianin, A | 1 |
| Roch-Arveiller, M | 1 |
| Giroud, JP | 1 |
| Hakim, J | 1 |
| Kurihara, A | 1 |
| Tsurufuji, S | 3 |
| Burka, JF | 3 |
| Paterson, NA | 2 |
| Rothberg, KG | 1 |
| Hitchcock, M | 1 |
| Yoshino, S | 2 |
| Kanaoka, K | 1 |
| Morley, J | 1 |
| Beets, JL | 1 |
| Bray, MA | 1 |
| Paul, W | 1 |
| Hedman, SE | 1 |
| Andersson, RG | 1 |
| Varoqua, S | 1 |
| Lin-Greenberg, A | 1 |
| Brown, M | 1 |
| Bandeira-Melo, C | 1 |
| Singh, Y | 1 |
| Cordeiro, RS | 1 |
| e Silva, PM | 1 |
| Martins, MA | 1 |
| Niki, H | 1 |
| Tominaga, Y | 1 |
| Watanabe-Kobayashi, M | 1 |
| Mue, S | 1 |
| Szebeni, J | 1 |
| Fontana, JL | 1 |
| Wassef, NM | 1 |
| Mongan, PD | 1 |
| Morse, DS | 1 |
| Dobbins, DE | 1 |
| Stahl, GL | 1 |
| Bünger, R | 1 |
| Alving, CR | 1 |
| Dworski, R | 1 |
| Jarzecka, K | 1 |
| Hubscher, T | 1 |
| Mathé, AA | 1 |
| Yen, SS | 1 |
| Sohn, R | 1 |
| Hedqvist, P | 2 |
| Pelus, LM | 1 |
| Strausser, HR | 1 |
| Surovikina, MS | 1 |
| Odinokova, VA | 1 |
| Paleev, NR | 1 |
| Gurevich, MA | 1 |
| Iankovskaia, MO | 1 |
| Chand, N | 2 |
| Eyre, P | 1 |
| Johnston, MG | 1 |
| Hay, JB | 1 |
| Movat, HZ | 1 |
| Cohn, MA | 1 |
| Baier, H | 1 |
| Wanner, A | 4 |
| Miyazawa, K | 1 |
| Mikami, T | 1 |
| Miyasaka, K | 1 |
| Aonuma, S | 1 |
| Tomioka, K | 1 |
| Jackowski, JT | 1 |
| Abraham, WM | 4 |
| Yang, ZJ | 1 |
| Biggs, DF | 1 |
| Zhang, S | 1 |
| Castro, GA | 1 |
| Ring, J | 1 |
| Walz, U | 1 |
| Schulman, ES | 1 |
| Anderson, CL | 1 |
| Briand, H | 1 |
| Scott-Savage, P | 1 |
| Pasutto, FM | 1 |
| Raud, J | 1 |
| Ono, N | 1 |
| Sunami, A | 1 |
| Yamasaki, Y | 1 |
| Yamamoto, N | 1 |
| Miyake, H | 1 |
| Poole, MD | 1 |
| Pillsbury, HC | 1 |
| Ford-Hutchinson, AW | 1 |
| Hamel, R | 1 |
| McFarlane, CS | 1 |
| Creese, BR | 1 |
| Temple, DM | 1 |
| Hand, JM | 1 |
| Schwalm, SF | 1 |
| Lewis, AJ | 1 |
| Diamantis, W | 1 |
| Sofia, RD | 1 |
| Hirasawa, N | 1 |
| Sugio, K | 1 |
| Lanes, S | 1 |
| Stevenson, JS | 1 |
| Codias, E | 2 |
| Hernandez, A | 1 |
| Sielczak, MW | 1 |
| Kannan, MS | 1 |
| Davis, C | 1 |
| Sankaranarayanan, A | 1 |
| Ladenius, AR | 1 |
| Kannan, L | 1 |
| Long, WM | 1 |
| Yerger, LD | 1 |
| Martinez, H | 1 |
| Sprung, CL | 1 |
| Sielczak, M | 1 |
| Mella, JF | 1 |
| Etienne, A | 1 |
| Soulard, C | 1 |
| Touvay, C | 1 |
| Clostre, F | 1 |
| Braquet, P | 1 |
| Kubanova, AA | 1 |
| Calabro, JJ | 1 |
| Katz, RM | 1 |
| Maltz, BA | 1 |
| Müller, P | 1 |
| Dörr, A | 1 |
| Dörr, M | 1 |
| Thoss, K | 1 |
| Raabe, G | 1 |
| Szarmach, H | 1 |
| Poniecka, H | 1 |
| Suc, JM | 1 |
| Conte, J | 1 |
5 reviews available for indomethacin and Hypersensitivity
| Article | Year |
|---|---|
Regulation of allergic responses by prostaglandins: a review.
Topics: Anaphylaxis; Anti-Inflammatory Agents; Humans; Hypersensitivity; Hypersensitivity, Delayed; Indometh | 1980 |
Prostaglandins and the immune response.
Topics: Animals; Antibody Formation; B-Lymphocytes; Cyclic AMP; Cyclic GMP; Cytotoxicity Tests, Immunologic; | 1977 |
Nonsteroidal anti-inflammatory drugs: a review. New applications in hypersensitivity reactions of cattle and horses.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents; Arthritis; Ascariasis; Aspirin; Cattle; Cattle Disea | 1977 |
Prostaglandins and other metabolites of arachidonic acid. An overview for the otolaryngologist.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Blo | 1985 |
A critical reappraisal of juvenile rheumatoid arthritis.
Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine | 1971 |
57 other studies available for indomethacin and Hypersensitivity
| Article | Year |
|---|---|
Identification of determinants of ligand binding affinity and selectivity in the prostaglandin D2 receptor CRTH2.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Cell Line; Cell Mov | 2005 |
Mast cell mediators cause early allergic bronchoconstriction in guinea-pigs in vivo: a model of relevance to asthma.
Topics: Acetates; Animals; Asthma; Bronchial Hyperreactivity; Constriction, Pathologic; Cyclopropanes; Disea | 2013 |
Cyclooxygenase inhibition abrogates aeroallergen-induced immune tolerance by suppressing prostaglandin I2 receptor signaling.
Topics: Air Pollution; Allergens; Animals; Enzyme Inhibitors; Epoprostenol; Humans; Hypersensitivity; Immune | 2014 |
The traditional Japanese medicine hangeshashinto alleviates oral ulcer-induced pain in a rat model.
Topics: Acetic Acid; Administration, Topical; Analgesics; Animals; Disease Models, Animal; Drugs, Chinese He | 2016 |
Prostaglandin I2 Suppresses Proinflammatory Chemokine Expression, CD4 T Cell Activation, and STAT6-Independent Allergic Lung Inflammation.
Topics: Allergens; Animals; Antihypertensive Agents; Asthma; CD4-Positive T-Lymphocytes; Cell Proliferation; | 2016 |
Immunomodulatory, analgesic and antipyretic effects of violacein isolated from Chromobacterium violaceum.
Topics: Acetic Acid; Analgesics; Anaphylaxis; Animals; Behavior, Animal; Chromobacterium; Dose-Response Rela | 2010 |
Allergic sensitization enhances anion current responsiveness of murine trachea to PAR-2 activation.
Topics: Amiloride; Animals; Asthma; Benzoates; Bestrophins; Chloride Channels; Eye Proteins; Hypersensitivit | 2012 |
Toward homeostasis: regulatory dendritic cells from the bone marrow of mice with inflammation of the airways and peritoneal cavity.
Topics: Alum Compounds; Animals; B7-2 Antigen; Bone Marrow Cells; CD11c Antigen; Cell Differentiation; Cell | 2012 |
Cyclooxygenase inhibition augments allergic inflammation through CD4-dependent, STAT6-independent mechanisms.
Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclooxygenase Inhibitors; Cytokine | 2005 |
Structural and functional comparison of mast cells in the pregnant versus nonpregnant human uterus.
Topics: Ambrosia; Antigens, Plant; Case-Control Studies; Cell Count; Cyclooxygenase Inhibitors; Diphenhydram | 2006 |
Involvement of cyclooxygenase-2 in allergic nasal inflammation in rats.
Topics: Animals; Carbazoles; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Electroenc | 2006 |
Possible involvement of 5-lipoxygenase metabolite in itch-associated response of mosquito allergy in mice.
Topics: Animals; Arachidonate 5-Lipoxygenase; Betamethasone Valerate; Bridged Bicyclo Compounds, Heterocycli | 2007 |
The modulation of adrenergic airway tone in normal and ascaris-sensitive beagle dogs.
Topics: Adrenergic alpha-Agonists; Animals; Ascaris; Dinoprost; Dogs; Female; Hypersensitivity; In Vitro Tec | 1982 |
Augmentation of allergic histamine release from human leukocytes by nonsteroidal anti-inflammatory-analgesic agents.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aurothioglucose; Dust; Female; Flufenamic Acid; Fluo | 1980 |
The late phase skin reaction: paradigm or epiphenomena?
Topics: Adrenal Cortex Hormones; Animals; Arthus Reaction; Chemotaxis, Leukocyte; Dermatitis, Atopic; Diseas | 1983 |
Arachidonate metabolites in acute and chronic allergic air pouch inflammation in rats and the anti-inflammatory effects of indomethacin and dexamethasone.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dexamethasone; Hypersensitivity; Indomethacin; Lipoxyg | 1984 |
Specific inhibition of lymphocyte-proliferation responses by adherent suppressor cells in diffuse cutaneous leishmaniasis.
Topics: Adolescent; Antigens; Cell Adhesion; Female; Humans; Hypersensitivity; Immune Tolerance; Indomethaci | 1982 |
In vivo effects of indomethacin and flurbiprofen on the locomotion of neutrophils elicited by immune and non-immune inflammation in the rat.
Topics: Animals; Cell Movement; Flurbiprofen; Hypersensitivity; In Vitro Techniques; Indomethacin; Inflammat | 1984 |
Reduction by dexamethasone of chemotactic activity in inflammatory exudates.
Topics: Animals; Chemotaxis, Leukocyte; Dexamethasone; Exudates and Transudates; Hypersensitivity; Indometha | 1984 |
Enhancement of antigen-induced tracheal contraction by cyclooxygenase inhibition.
Topics: Airway Resistance; Animals; Cyclooxygenase Inhibitors; Guinea Pigs; Hypersensitivity; Indomethacin; | 1980 |
Evidence for lipoxygenase pathway involvement in allergic tracheal contraction.
Topics: Animals; Arachidonic Acids; Aspirin; Asthma; Constriction, Pathologic; Guinea Pigs; Histamine; Hyper | 1980 |
In vitro biosynthesis of cyclooxygenase metabolites in ovalbumin-sensitized and control lungs of guinea pigs.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Guinea Pigs; Hypersensitivity; In Vitro Techniques; In | 1982 |
A possible role of arachidonate metabolism in allergic air pouch inflammation in rats. Anti-inflammatory effect of indomethacin and dexamethasone and the level of prostaglandin E2 in the exudate.
Topics: Animals; Arachidonic Acids; Cycloheximide; Dexamethasone; Dinoprostone; Exudates and Transudates; Hy | 1982 |
Effects of SRS (slow reacting substance) on cyclic nucleotides in guinea pig tracheal muscle.
Topics: Animals; Chromones; Female; Guinea Pigs; Hypersensitivity; Indomethacin; Male; Muscle Contraction; M | 1982 |
Polyarthritis in an elderly man with bladder cancer.
Topics: Administration, Intravesical; Aged; Arthritis; BCG Vaccine; Carcinoma, Transitional Cell; Drug Thera | 1994 |
Involvement of prostaglandins in the down-regulation of allergic plasma leakage observed in rats undergoing pleural eosinophilia.
Topics: Animals; Aspirin; Dinoprostone; Down-Regulation; Eosinophils; Female; Hypersensitivity; Indomethacin | 1996 |
Possible participation of cyclooxygenase-2 in the recurrence of allergic inflammation in rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cycloo | 1997 |
Hemodynamic changes induced by liposomes and liposome-encapsulated hemoglobin in pigs: a model for pseudoallergic cardiopulmonary reactions to liposomes. Role of complement and inhibition by soluble CR1 and anti-C5a antibody.
Topics: Animals; Complement Activation; Complement C5a; Complement System Proteins; Female; Hemodynamics; He | 1999 |
Cyclooxygenase inhibition increases interleukin 5 and interleukin 13 production and airway hyperresponsiveness in allergic mice.
Topics: Animals; Arachidonic Acid; Chemokines, CC; Cyclooxygenase Inhibitors; Female; Hypersensitivity; Immu | 2000 |
Role of the eosinophil in the allergic reactions. II. Release of prostaglandins from human eosinophilic leukocytes.
Topics: Adenosine Diphosphate; Antibodies; Biological Assay; Chromatography, Thin Layer; Eosinophils; Histam | 1975 |
Release of prostaglandins and histamine from sensitized and anaphylactic guinea pig lungs--changes in cyclic AMP levels.
Topics: Anaphylaxis; Animals; Cyclic AMP; Deoxyglucose; Epinephrine; Guinea Pigs; Histamine Release; Hyperse | 1977 |
[Changes in the kinin system components and structure of the myocardium under the influence of antikinin preparations in allergic myocarditis in rabbits].
Topics: Aminocaproic Acid; Animals; Aprotinin; Aspirin; Heart; Hypersensitivity; Indomethacin; Kininogens; K | 1976 |
Kinetics of prostaglandin production in various inflammatory lesions, measured in draining lymph.
Topics: Animals; Capillary Permeability; Carrageenan; Escherichia coli; Female; Hypersensitivity; Immunizati | 1979 |
Failure of hypoxic pulmonary vasoconstriction in the canine asthma model. Effect of prostaglandin inhibitors.
Topics: Animals; Ascaris; Aspirin; Asthma; Dogs; Hypersensitivity; Hypoxia; Indomethacin; Lung; Oxygen; Pros | 1978 |
Experimental models of acute and chronic sialoadenitis in the guinea pig.
Topics: Acute Disease; Animals; Chronic Disease; Cyclophosphamide; Disease Models, Animal; Guinea Pigs; Hype | 1992 |
Characterization of sulfidopeptide leukotriene responses in sheep tracheal smooth muscle in vitro.
Topics: Animals; Ascaris; Borates; Carbachol; Cysteine; Female; Hypersensitivity; In Vitro Techniques; Indom | 1991 |
Muscarinic-receptor functioning in tracheas from normal and ovalbumin-sensitive guinea pigs.
Topics: Aerosols; Animals; Asthma; Bethanidine; Electric Stimulation; Female; Gallamine Triethiodide; Guinea | 1991 |
Involvement of type I hypersensitivity in rapid rejection of Trichinella spiralis from adult rats.
Topics: Animals; Diphenhydramine; Hypersensitivity; Immunization, Passive; Indomethacin; Intestinal Mucosa; | 1990 |
Indomethacin enhances in vitro histamine release induced by anti-IgE and Ca-ionophore but inhibits C5a-induced release reactions from basophils of atopics and normals.
Topics: Adolescent; Adult; Antibodies, Anti-Idiotypic; Basophils; Calcimycin; Complement C5; Complement C5a; | 1985 |
Lung hypersensitivity responses: dissociation of human lung mast cell leukotriene C4 (LTC4) from histamine release.
Topics: Animals; Catechols; Histamine Release; Humans; Hypersensitivity; Indomethacin; Lung; Masoprocol; Mas | 1985 |
Leukotriene D4 and platelet-activating factor-acether antagonists on allergic and arachidonic acid-induced reactions in guinea pig airways.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Guinea Pigs; Hypersensitivity; In Vitro Techniques; In | 1989 |
Dual action of prostaglandin E2 in allergic inflammation.
Topics: Animals; Cheek; Cricetinae; Dinoprostone; Hypersensitivity; Indomethacin; Inflammation; Leukocytes; | 1989 |
Effects of proglumetacin maleate and its major metabolites on allergic air pouch inflammation in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Dinoprostone; | 1987 |
Pulmonary responses to exogenous leukotrienes.
Topics: Allergens; Animals; Arachidonic Acids; Ascaris; Bronchi; Bronchial Provocation Tests; Bronchial Spas | 1985 |
The mediators of allergic contraction of human airway smooth muscle: a comparison of bronchial and lung parenchymal strip preparations.
Topics: Bronchi; Chromones; Cromolyn Sodium; Histamine; Humans; Hypersensitivity; In Vitro Techniques; Indom | 1986 |
Antagonism of antigen-induced contraction of isolated guinea-pig trachea by 5-lipoxygenase inhibitors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Anima | 1986 |
Modulation of in vitro anaphylaxis of guinea-pig isolated tracheal segments by azelastine, inhibitors of arachidonic acid metabolism and selected antiallergic drugs.
Topics: Airway Resistance; Anaphylaxis; Animals; Antigens; Arachidonic Acid; Arachidonic Acids; Guinea Pigs; | 1986 |
Vascular permeability responses and the role of prostaglandin E2 in an experimental allergic inflammation of air pouch type in rats.
Topics: Animals; Capillary Permeability; Diclofenac; Dinoprostone; Hypersensitivity; Indomethacin; Inflammat | 1986 |
Indomethacin and FPL-57231 inhibit antigen-induced airway hyperresponsiveness in sheep.
Topics: Airway Resistance; Animals; Antigens; Arachidonic Acid; Arachidonic Acids; Bronchi; Chromones; Hyper | 1986 |
Pharmacological characterization of airway smooth muscle responses to antigen in ascaris-sensitive dogs.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Airway Resistance; Animals; Antigens, Helminth; Arac | 1986 |
Modification of bronchial blood flow during allergic airway responses.
Topics: Airway Resistance; Animals; Ascaris; Bronchi; Cromolyn Sodium; Female; Hemodynamics; Hypersensitivit | 1988 |
Ciliary responsiveness in allergic and nonallergic airways.
Topics: Alprostadil; Animals; Ascaris; Asthma; Cilia; Dinoprostone; Dose-Response Relationship, Drug; Epithe | 1986 |
In vivo anti-allergic and anti-inflammatory effects of drugs that inhibit lipoxygenase activity in vitro.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenas | 1985 |
[Role of prostaglandins and cyclic nucleotides in the development of allergic reactions in eczema patients].
Topics: Eczema; Humans; Hypersensitivity; Indomethacin; Nucleotides, Cyclic; Prostaglandins | 1985 |
BSA-induced allergic arthritis and formal-induced non-allergic arthritis in rabbits. 3. Anti-inflammatory intraarticular action of indometacin in BSA-induced allergic arthritis in rabbits.
Topics: Animals; Arthritis; Disease Models, Animal; Freund's Adjuvant; Hypersensitivity; Indomethacin; Injec | 1974 |
[Clinical obervations on the usefulness of Methindol in treatment of selected allergic dermatoses].
Topics: Adolescent; Adult; Aged; Drug Tolerance; Humans; Hypersensitivity; Indomethacin; Middle Aged; Skin D | 1973 |
Treatment of glomerulonephritis with indomethacin and heparin.
Topics: Adolescent; Adult; Aged; Child; Female; Glomerulonephritis; Heparin; Humans; Hypersensitivity; Indom | 1973 |