Page last updated: 2024-10-29

indomethacin and Hypercapnia

indomethacin has been researched along with Hypercapnia in 57 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.

Research Excerpts

ExcerptRelevanceReference
"We investigated the effect of moderate (FiO2 13%) and light hypoxia (FiO2 17%) and hypercapnia (CO2 2-4%) with or without indomethacin on circulating levels of endothelin/endothelins (ET) and cerebral blood flow (CBF) in healthy volunteers."9.07Endothelin-1 and cerebral blood flow: influence of hypoxia, hypercapnia and indomethacin on circulating endothelin levels in healthy volunteers. ( Bünemann, L; Bøgeskov Nielsen, L; Freundlich, M; Jensen, KA; Therkelsen, K; Thorshauge, H, 1994)
"To investigate using an arterial spin tagging (AST) approach the effect of indomethacin on the cerebral blood flow (CBF) response to hypercapnia."7.71Effects of indomethacin on cerebral blood flow at rest and during hypercapnia: an arterial spin tagging study in humans. ( Frank, JA; Lewis, BK; McLaughlin, AC; St Lawrence, KS; Weinberger, DR; Ye, FQ, 2002)
" We therefore investigated the effect of indomethacin on the CBF increase caused by acetazolamide (Az), a drug that induces brain extracellular acidosis, which triggers its effect on CBF."7.68Indomethacin abolishes cerebral blood flow increase in response to acetazolamide-induced extracellular acidosis: a mechanism for its effect on hypercapnia? ( Lassen, NA; Paulson, OB; Wang, Q, 1993)
"Responses of pial arterioles to topically applied arachidonic acid, conversion of exogenous arachidonic acid to prostanoids, and pial arteriolar dilation to hypercapnia were examined before and at progressive times after treatment with indomethacin (5 mg/kg i."7.68Effects of indomethacin on cerebral vasodilator responses to arachidonic acid and hypercapnia in newborn pigs. ( Armstead, WM; Leffler, CW; Mirro, R; Parfenova, H; Shibata, M; Zuckerman, S, 1993)
"To study the contribution of prostaglandins to cerebral vasodilatation during hypercapnia, we inhibited prostaglandin synthesis with indomethacin."7.66Effects of indomethacin on cerebral blood flow during hypercapnia in cats. ( Busija, DW; Heistad, DD, 1983)
"We investigated the effect of moderate (FiO2 13%) and light hypoxia (FiO2 17%) and hypercapnia (CO2 2-4%) with or without indomethacin on circulating levels of endothelin/endothelins (ET) and cerebral blood flow (CBF) in healthy volunteers."5.07Endothelin-1 and cerebral blood flow: influence of hypoxia, hypercapnia and indomethacin on circulating endothelin levels in healthy volunteers. ( Bünemann, L; Bøgeskov Nielsen, L; Freundlich, M; Jensen, KA; Therkelsen, K; Thorshauge, H, 1994)
" MCA velocity (MCAv) was measured at baseline and during stepped hypercapnia (2%, 4%, and 6% FiCO2) before and after cyclooxygenase inhibition using indomethacin."3.79Cerebrovascular reactivity is associated with maximal aerobic capacity in healthy older adults. ( Barnes, JN; Johnson, CP; Joyner, MJ; Kluck, BN; Taylor, JL, 2013)
" Corticocerebral blood flow was measured by hydrogen polarography during hypercapnia and acetazolamide stimuli in conscious rabbits."3.71Influence of nitrovasodilators and cyclooxygenase inhibitors on cerebral vasoreactivity in conscious rabbits. ( Barzó, P; Bodosi, M; Csete, K; Papp, JG, 2001)
" We therefore investigated the effect of indomethacin on the CBF increase caused by acetazolamide (Az), a drug that induces brain extracellular acidosis, which triggers its effect on CBF."3.68Indomethacin abolishes cerebral blood flow increase in response to acetazolamide-induced extracellular acidosis: a mechanism for its effect on hypercapnia? ( Lassen, NA; Paulson, OB; Wang, Q, 1993)
"Responses of pial arterioles to topically applied arachidonic acid, conversion of exogenous arachidonic acid to prostanoids, and pial arteriolar dilation to hypercapnia were examined before and at progressive times after treatment with indomethacin (5 mg/kg i."3.68Effects of indomethacin on cerebral vasodilator responses to arachidonic acid and hypercapnia in newborn pigs. ( Armstead, WM; Leffler, CW; Mirro, R; Parfenova, H; Shibata, M; Zuckerman, S, 1993)
" Diameter of one pial arteriole was determined during baseline conditions and topical application of 10(-5) M phorbol 12, 13-dibutyrate (PDB) and during subsequent application of one of the following: arterial hypercapnia (inhalation of 10% CO2), topical application of cerebrospinal fluid with 12 mM K+, or topical application of 10(-5) M isoproterenol in cerebrospinal fluid."3.68Reversal by increased CSF [H+] and [K+] of phorbol ester-induced arteriolar constriction in piglets. ( Busija, DW; Chen, J, 1992)
"Using awake, chronically catheterized newborn pigs, we measured cerebral blood flow (CBF), net cerebral vascular 6-keto-prostaglandin F1 alpha production, and cerebral metabolic rate of oxygen (CMRO2) during hypercapnia and during hypercapnia at increased mean airway pressure (Paw), both before and after treatment with indomethacin."3.68Pressure ventilation increases brain vascular prostacyclin production in newborn pigs. ( Armstead, WM; Busija, DW; Leffler, CW; Mirro, R, 1990)
"The effect of cyclooxygenase inhibition by indomethacin on regional cerebral blood flow (CBF) during hypocapnia induced by hyperventilation and during hypercapnia induced by CO2 inhalation was examined."3.67Effect of indomethacin on the regulation of cerebral blood flow during respiratory alkalosis in newborn piglets. ( DeGiulio, PA; Delivoria-Papadopoulos, M; Mishra, OP; Roth, RA; Wagerle, LC, 1989)
"Cerebral blood flow (CBF) was measured in conscious rats treated with indomethacin, diclofenac or the vehicle for indomethacin during hypercapnia of three different degrees."3.67Effects of indomethacin and diclofenac on cerebral blood flow in hypercapnic conscious rats. ( Quintana, A; Quintana, MA; Raczka, E, 1988)
"Although results obtained in baboons and rats have demonstrated that the fatty acid cyclo-oxygenase inhibitor indomethacin reduces cerebral blood flow (CBF) under control conditions and markedly attenuates the CBF response to hypercapnia, nonconfirmatory results have been obtained in rabbits and cats."3.66Effects of indomethacin on cerebral blood flow and oxygen consumption in barbiturate-anesthetized Normocapnic and hypercapnic rats. ( Dahlgren, N; Siesjö, BK, 1981)
" The inhibition of prostaglandin synthesis with indomethacin or aspirin blocks the vasodilatatory effect of hypercapnia and, to a lesser extent, of hypoxia."3.66[The metabolic regulation of the retinal blood flow and the role of prostaglandins (author's transl)]. ( Pournaras, C; Tsacopoulos, M, 1978)
"To further our understanding of central sleep apnea (CSA) at high altitude during acclimatization, we tested the hypothesis that pharmacologically altering cerebral blood flow (CBF) would alter the severity of CSA at high altitude."2.79Influence of cerebral blood flow on central sleep apnea at high altitude. ( Ainslie, PN; Basnyat, R; Burgess, KR; Dawson, A; Donnelly, J; Lucas, RA; Lucas, SJ; Peebles, KC; Shepherd, K; Swart, M; Thomas, KN, 2014)
"The functional hemodynamic parameter mean flow velocity (MFV) was assessed at rest, before and 90min after 100mg of INDO, and during the BHT."2.78Effect of indomethacin on cerebrovascular reactivity in patients with type 2 diabetes mellitus. ( Demarin, V; Drenjancevic, I; Rahelic, D; Vuletic, V, 2013)
"Indomethacin (INDO) has the potential to be a useful tool to explore the influence of cerebral blood flow and its responses to CO(2) on ventilatory control."2.76Influence of indomethacin on the ventilatory and cerebrovascular responsiveness to hypoxia. ( Ainslie, PN; Burgess, KR; Cotter, JD; Fan, JL; Lucas, RA; Lucas, SJ; Peebles, KC; Thomas, KN, 2011)
"Indomethacin (IND) is a non-steroidal anti-inflammatory agent with unique effects on cerebral blood flow physiology which may be of benefit in reducing elevated ICP in TBI patients."2.40Indomethacin: a review of its cerebral blood flow effects and potential use for controlling intracranial pressure in traumatic brain injury patients. ( Rhoney, DH; Slavik, RS, 1999)
"Indomethacin (IMC) was used as cyclooxygenase inhibitor."1.31Cyclooxygenase-pathway participates in the regulation of regional cerebral blood flow in response to neuronal activation under normo- and hypercapnia. ( Bakalova, RA; Kanno, I; Matsuura, T, 2002)
" We hypothesized that with chronic administration of indomethacin the piglet would advance the role of the NO system in cerebrovascular responses."1.31Chronic administration of indomethacin increases role of nitric oxide in hypercapnic cerebrovasodilation in piglets. ( Son, M; Zuckerman, S, 2002)
"Ibuprofen treatment (30 mg/kg) had no effect on pial arteriolar diameter during normoxia or hypoxia, and pretreatment did not alter dilation to hypoxia."1.30Cerebral arteriolar dilation to hypoxia: role of prostanoids. ( Leffler, CW; Parfenova, H, 1997)
"Since chronic hypertension has been associated with impaired endothelial function, we designed a study to find out whether hypercapnic cerebral blood flow and its nitric oxide- and prostaglandin-sensitive component is reduced in spontaneously hypertensive rats (SHR) compared with normotensive controls."1.30Hypercapnic cerebral blood flow in spontaneously hypertensive rats. ( Casadei, B; Heinert, G; Paterson, DJ, 1998)
"We studied the effect of systemic hypoxemia and hypercarbia on the bronchial blood flow in open-chested, anesthetized dogs."1.27Hypoxia and hypercarbia increase bronchial blood flow through bronchopulmonary anastomoses in anesthetized dogs. ( Albert, RK; Butler, J; Charan, NB; Kirk, W; Lakshminarayan, S, 1986)

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-199020 (35.09)18.7374
1990's18 (31.58)18.2507
2000's11 (19.30)29.6817
2010's8 (14.04)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JN2
Taylor, JL1
Kluck, BN1
Johnson, CP1
Joyner, MJ3
Vuletic, V1
Drenjancevic, I1
Rahelic, D1
Demarin, V1
Harrell, JW1
Schrage, WG1
Burgess, KR2
Lucas, SJ2
Shepherd, K1
Dawson, A1
Swart, M1
Thomas, KN2
Lucas, RA2
Donnelly, J1
Peebles, KC2
Basnyat, R1
Ainslie, PN3
Beaudin, AE1
Waltz, X1
Pun, M1
Wynne-Edwards, KE1
Ahmed, SB1
Anderson, TJ1
Hanly, PJ1
Poulin, MJ1
Hoiland, RL1
Tymko, MM1
Bain, AR1
Wildfong, KW1
Monteleone, B1
Xie, A1
Skatrud, JB1
Barczi, SR1
Reichmuth, K1
Morgan, BJ1
Mont, S1
Dempsey, JA1
Ivancev, V1
Bakovic, D1
Obad, A1
Breskovic, T1
Palada, I1
Dujic, Z1
Lenti, L1
Zimmermann, A1
Kis, D1
Oláh, O1
Tóth, GK1
Hegyi, O1
Busija, DW8
Bari, F2
Domoki, F2
Fan, JL1
Cotter, JD1
Schmidt, JE1
Nicholson, WT1
St Lawrence, KS1
Ye, FQ1
Lewis, BK1
Weinberger, DR1
Frank, JA1
McLaughlin, AC1
Bakalova, RA1
Matsuura, T1
Kanno, I1
Nagy, K1
Temesvári, P1
Siesjö, BK4
Nilsson, B1
Heistad, DD1
Jackson, EK1
Gerkens, JF1
Zimmerman, JB1
Uderman, HD1
Oates, JA1
Workman, RJ1
Branch, RA1
Gabrielian, ES2
Amroian, EA2
Hoffman, WE1
Albrecht, RF1
Pelligrino, D1
Miletich, DJ1
Dahlgren, N1
Wei, EP1
Ellis, EF1
Kontos, HA1
Parfenova, H4
Shibata, M5
Zuckerman, S4
Leffler, CW12
Mirro, R3
Pharris, LJ1
Therkelsen, K1
Jensen, KA1
Freundlich, M1
Thorshauge, H1
Bünemann, L1
Bøgeskov Nielsen, L1
Wang, Q1
Paulson, OB1
Lassen, NA1
Armstead, WM3
Hsu, P2
Nilsson, F1
Björkman, S1
Rosén, I1
Messeter, K1
Nordström, CH1
Zuckerman, SL1
Rudinsky, BF1
Lozon, M1
Bell, A1
Hipps, R1
Meadow, WL1
Yamaguchi, K1
Suzuki, K1
Naoki, K1
Nishio, K1
Sato, N1
Takeshita, K1
Kudo, H1
Aoki, T1
Suzuki, Y1
Miyata, A1
Tsumura, H1
Okazaki, K1
Endou, M1
Okumura, F1
Heinert, G1
Casadei, B1
Paterson, DJ1
Slavik, RS1
Rhoney, DH1
Stark, AR1
Carlo, WA1
Tyson, JE1
Papile, LA1
Wright, LL1
Shankaran, S1
Donovan, EF1
Oh, W1
Bauer, CR1
Saha, S1
Poole, WK1
Stoll, BJ1
Csete, K1
Barzó, P1
Bodosi, M1
Papp, JG1
Willis, AP1
Son, M1
Zhang, Y1
Megrabian, VI1
Sakabe, T1
Pournaras, C2
Tsacopoulos, M2
Chapuis, P1
Chen, J1
Norins, NA1
Wendelberger, K1
Hoffman, RG1
Keller, PA1
Madden, JA1
DeGiulio, PA1
Roth, RA1
Mishra, OP1
Delivoria-Papadopoulos, M1
Wagerle, LC1
Quintana, A1
Raczka, E1
Quintana, MA1
Charan, NB1
Lakshminarayan, S1
Albert, RK1
Kirk, W1
Butler, J1
Fletcher, AM1
Beasley, DG1
Hessler, JR1
Green, RS1
Pickard, JD1
Mackenzie, ET1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Role of Shear Stress in the Cerebrovascular Response to Acute Exercise[NCT03722953]18 participants (Actual)Interventional2018-12-01Completed
Effects of Acute Exercise Intensity on Cerebral Blood Flow and Cognitive Function in Older Adults[NCT05131217]13 participants (Actual)Interventional2022-01-14Completed
MRI Biomarkers of Risk in Sedentary and Exercise Trained Humans[NCT02729428]71 participants (Actual)Observational2016-04-30Completed
Cerebral Vasodilator Responses in Sedentary and Exercise Trained Humans[NCT02653638]Early Phase 180 participants (Actual)Interventional2016-06-30Completed
Brain Blood Flow Response to Hypercapnia in Healthy Adults: The Effect of Age and Sex[NCT02840851]46 participants (Actual)Observational2016-11-30Completed
Autonomic Dysfunction, Brain Blood Flow and Cognitive Decline in Veterans With Gulf War Illness[NCT04586049]70 participants (Anticipated)Observational2023-05-16Recruiting
The Impact of Cerebral Anatomical Variations on Cerebrovascular Reactivity[NCT05396287]80 participants (Anticipated)Observational2022-07-19Enrolling by invitation
Cerebrovascular Outcomes in Ischemic Heart Disease Patients Undergoing Cardiac Rehabilitation[NCT02715661]140 participants (Actual)Interventional2016-03-31Completed
Randomized Trial of Minimal Ventilator Support and Early Corticosteroid Therapy to Increase Survival Without Chronic Lung Disease in Extremely-Low-Birth-Weight Infants[NCT00005777]Phase 3220 participants (Actual)Interventional1998-02-28Terminated (stopped due to The trial was halted because of unanticipated nonrespiratory adverse events related to dexamethasone therapy.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for indomethacin and Hypercapnia

ArticleYear
Prostaglandins and the cerebral circulation.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1982, Volume: 10

    Topics: Animals; Brain; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Dose-Response Relationship,

1982
Cerebral metabolic rate in hypercarbia--a controversy.
    Anesthesiology, 1980, Volume: 52, Issue:6

    Topics: Amino Acids; Animals; Brain; Carbon Dioxide; Cerebrovascular Circulation; Citric Acid Cycle; Diazepa

1980
Indomethacin: a review of its cerebral blood flow effects and potential use for controlling intracranial pressure in traumatic brain injury patients.
    Neurological research, 1999, Volume: 21, Issue:5

    Topics: Adult; Animals; Barbiturates; Birth Injuries; Brain Damage, Chronic; Brain Injuries; Cerebrovascular

1999

Trials

9 trials available for indomethacin and Hypercapnia

ArticleYear
Effect of indomethacin on cerebrovascular reactivity in patients with type 2 diabetes mellitus.
    Diabetes research and clinical practice, 2013, Volume: 101, Issue:1

    Topics: Adolescent; Adult; Aged; Brain; Cardiovascular Agents; Cerebrovascular Circulation; Diabetes Mellitu

2013
Cyclooxygenase-derived vasoconstriction restrains hypoxia-mediated cerebral vasodilation in young adults with metabolic syndrome.
    American journal of physiology. Heart and circulatory physiology, 2014, Jan-15, Volume: 306, Issue:2

    Topics: Adult; Blood Flow Velocity; Carbon Dioxide; Cyclooxygenase Inhibitors; Double-Blind Method; Female;

2014
Influence of cerebral blood flow on central sleep apnea at high altitude.
    Sleep, 2014, Oct-01, Volume: 37, Issue:10

    Topics: Acclimatization; Acetazolamide; Administration, Intravenous; Administration, Oral; Adult; Altitude;

2014
Human intermittent hypoxia-induced respiratory plasticity is not caused by inflammation.
    The European respiratory journal, 2015, Volume: 46, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cross-Over Studies; Double-Blind Method;

2015
Carbon dioxide-mediated vasomotion of extra-cranial cerebral arteries in humans: a role for prostaglandins?
    The Journal of physiology, 2016, 06-15, Volume: 594, Issue:12

    Topics: Adolescent; Adult; Carbon Dioxide; Carotid Artery, Internal; Cerebrovascular Circulation; Cyclooxyge

2016
Effects of indomethacin on cerebrovascular response to hypercapnea and hypocapnea in breath-hold diving and obstructive sleep apnea.
    Respiratory physiology & neurobiology, 2009, May-15, Volume: 166, Issue:3

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Cardiovascular Agents; Cerebrovascular Circulation; Cros

2009
Effects of indomethacin on cerebrovascular response to hypercapnea and hypocapnea in breath-hold diving and obstructive sleep apnea.
    Respiratory physiology & neurobiology, 2009, May-15, Volume: 166, Issue:3

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Cardiovascular Agents; Cerebrovascular Circulation; Cros

2009
Effects of indomethacin on cerebrovascular response to hypercapnea and hypocapnea in breath-hold diving and obstructive sleep apnea.
    Respiratory physiology & neurobiology, 2009, May-15, Volume: 166, Issue:3

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Cardiovascular Agents; Cerebrovascular Circulation; Cros

2009
Effects of indomethacin on cerebrovascular response to hypercapnea and hypocapnea in breath-hold diving and obstructive sleep apnea.
    Respiratory physiology & neurobiology, 2009, May-15, Volume: 166, Issue:3

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Cardiovascular Agents; Cerebrovascular Circulation; Cros

2009
Influence of indomethacin on the ventilatory and cerebrovascular responsiveness to hypoxia.
    European journal of applied physiology, 2011, Volume: 111, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cerebrovascular Circulation; Female; Humans;

2011
Endothelin-1 and cerebral blood flow: influence of hypoxia, hypercapnia and indomethacin on circulating endothelin levels in healthy volunteers.
    Scandinavian journal of clinical and laboratory investigation, 1994, Volume: 54, Issue:6

    Topics: Adolescent; Adult; Cerebrovascular Circulation; Double-Blind Method; Endothelins; Female; Humans; Hy

1994
Adverse effects of early dexamethasone treatment in extremely-low-birth-weight infants. National Institute of Child Health and Human Development Neonatal Research Network.
    The New England journal of medicine, 2001, 01-11, Volume: 344, Issue:2

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dexamethasone; D

2001

Other Studies

45 other studies available for indomethacin and Hypercapnia

ArticleYear
Cerebrovascular reactivity is associated with maximal aerobic capacity in healthy older adults.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, May-15, Volume: 114, Issue:10

    Topics: Adult; Age Factors; Arterial Pressure; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat

2013
Cerebrovascular reactivity is associated with maximal aerobic capacity in healthy older adults.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, May-15, Volume: 114, Issue:10

    Topics: Adult; Age Factors; Arterial Pressure; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat

2013
Cerebrovascular reactivity is associated with maximal aerobic capacity in healthy older adults.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, May-15, Volume: 114, Issue:10

    Topics: Adult; Age Factors; Arterial Pressure; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat

2013
Cerebrovascular reactivity is associated with maximal aerobic capacity in healthy older adults.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, May-15, Volume: 114, Issue:10

    Topics: Adult; Age Factors; Arterial Pressure; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat

2013
Cerebrovascular reactivity is associated with maximal aerobic capacity in healthy older adults.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, May-15, Volume: 114, Issue:10

    Topics: Adult; Age Factors; Arterial Pressure; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat

2013
Cerebrovascular reactivity is associated with maximal aerobic capacity in healthy older adults.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, May-15, Volume: 114, Issue:10

    Topics: Adult; Age Factors; Arterial Pressure; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat

2013
Cerebrovascular reactivity is associated with maximal aerobic capacity in healthy older adults.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, May-15, Volume: 114, Issue:10

    Topics: Adult; Age Factors; Arterial Pressure; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat

2013
Cerebrovascular reactivity is associated with maximal aerobic capacity in healthy older adults.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, May-15, Volume: 114, Issue:10

    Topics: Adult; Age Factors; Arterial Pressure; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat

2013
Cerebrovascular reactivity is associated with maximal aerobic capacity in healthy older adults.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, May-15, Volume: 114, Issue:10

    Topics: Adult; Age Factors; Arterial Pressure; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat

2013
Influence of cerebral blood flow on breathing stability.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 106, Issue:3

    Topics: Adolescent; Adult; Blood Flow Velocity; Brain; Carbon Dioxide; Cardiovascular Agents; Cerebrovascula

2009
PACAP and VIP differentially preserve neurovascular reactivity after global cerebral ischemia in newborn pigs.
    Brain research, 2009, Aug-04, Volume: 1283

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Arterioles; Brain Ischemia; Cere

2009
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Adolescent; Adult; Aged; Aging; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Female; Huma

2012
Effects of indomethacin on cerebral blood flow at rest and during hypercapnia: an arterial spin tagging study in humans.
    Journal of magnetic resonance imaging : JMRI, 2002, Volume: 15, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Brain; Cerebrovascular Circulation;

2002
Cyclooxygenase-pathway participates in the regulation of regional cerebral blood flow in response to neuronal activation under normo- and hypercapnia.
    Prostaglandins, leukotrienes, and essential fatty acids, 2002, Volume: 67, Issue:6

    Topics: Acid-Base Equilibrium; Animals; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cerebral Cortex

2002
Selective inhibitors differentially affect cyclooxygenase-dependent pial arteriolar responses in newborn pigs.
    Pediatric research, 2005, Volume: 57, Issue:6

    Topics: Acetaminophen; Animals; Animals, Newborn; Arterioles; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxyge

2005
Effects of indomethacin on cerebral blood flow during hypercapnia in cats.
    The American journal of physiology, 1983, Volume: 244, Issue:4

    Topics: Animals; Blood Pressure; Brain; Carbon Dioxide; Cats; Cerebrovascular Circulation; Hypercapnia; Indo

1983
Role of prostaglandins in the response of the cerebral circulation to carbon dioxide in conscious rabbits.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1983, Volume: 3, Issue:3

    Topics: Animals; Carbon Dioxide; Cerebrovascular Circulation; Consciousness; Hypercapnia; Indomethacin; Micr

1983
Prostaglandin biosynthesis does not participate in hypercapnia-induced cerebral vasodilatation in the dog.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Cerebrovascular Circulation; Dogs; Epo

1983
[Effect of CO2 on thrombocyte aggregation in the cat].
    Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 97, Issue:4

    Topics: Animals; Cats; Cyclooxygenase Inhibitors; Hypercapnia; Indomethacin; Platelet Aggregation

1984
Effects of prostaglandins on the cerebral circulation in the coat.
    Prostaglandins, 1982, Volume: 23, Issue:6

    Topics: Animals; Cerebrovascular Circulation; Dinoprost; Dinoprostone; Epoprostenol; Female; Goats; Hypercap

1982
Effects of indomethacin on cerebral blood flow and oxygen consumption in barbiturate-anesthetized Normocapnic and hypercapnic rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1981, Volume: 1, Issue:1

    Topics: Anesthetics; Animals; Brain; Cerebrovascular Circulation; Hypercapnia; Indomethacin; Nitrous Oxide;

1981
Role of prostaglandins in pial arteriolar response to CO2 and hypoxia.
    The American journal of physiology, 1980, Volume: 238, Issue:2

    Topics: Animals; Arterioles; Benzene Derivatives; Carbon Dioxide; Cats; Hypercapnia; Hypoxia; Indomethacin;

1980
CO2 and cerebral circulation in newborn pigs: cyclic nucleotides and prostanoids in vascular regulation.
    The American journal of physiology, 1994, Volume: 266, Issue:4 Pt 2

    Topics: Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arterioles; Blood Vessels; Carbon Dioxide; Ce

1994
Permissive role of prostacyclin in cerebral vasodilation to hypercapnia in newborn pigs.
    The American journal of physiology, 1994, Volume: 267, Issue:1 Pt 2

    Topics: Animals; Animals, Newborn; Cerebrovascular Circulation; Dinoprostone; Epoprostenol; Hypercapnia; Ilo

1994
Inhibitory effect of indomethacin on prostacyclin receptor-mediated cerebral vascular responses.
    The American journal of physiology, 1995, Volume: 268, Issue:5 Pt 2

    Topics: Animals; Animals, Newborn; Arterioles; Aspirin; Cerebrovascular Circulation; Hypercapnia; Iloprost;

1995
Indomethacin abolishes cerebral blood flow increase in response to acetazolamide-induced extracellular acidosis: a mechanism for its effect on hypercapnia?
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1993, Volume: 13, Issue:4

    Topics: Acetazolamide; Acidosis; Animals; Carbon Dioxide; Cerebrovascular Circulation; Diclofenac; Extracell

1993
Effects of indomethacin on cerebral vasodilator responses to arachidonic acid and hypercapnia in newborn pigs.
    Pediatric research, 1993, Volume: 33, Issue:6

    Topics: Animals; Animals, Newborn; Arachidonic Acid; Arterioles; Cerebrovascular Circulation; Dinoprost; Din

1993
Prostanoid synthesis in response to high CO2 in newborn pig brain microvascular endothelial cells.
    The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 2

    Topics: Animals; Animals, Newborn; Calcimycin; Carbon Dioxide; Cells, Cultured; Cerebrovascular Circulation;

1993
Cerebral vasoconstriction by indomethacin in intracranial hypertension. An experimental investigation in pigs.
    Anesthesiology, 1995, Volume: 83, Issue:6

    Topics: Animals; Cerebrovascular Circulation; Hypercapnia; Indomethacin; Intracranial Pressure; Swine; Vascu

1995
Age dependence of cerebrovascular response mechanisms in domestic pigs.
    The American journal of physiology, 1996, Volume: 271, Issue:2 Pt 2

    Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Arterioles; Cerebrovascular Circulation; Cyclooxyge

1996
Group B streptococcal sepsis impairs cerebral vascular reactivity to acute hypercarbia in piglets.
    Pediatric research, 1996, Volume: 39, Issue:1

    Topics: Animals; Blood Pressure; Brain; Carbon Monoxide; Carotid Artery, Internal; Disease Models, Animal; H

1996
Cerebral arteriolar dilation to hypoxia: role of prostanoids.
    The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Arterioles; Cerebrovascular Circulation; Hy

1997
Response of intra-acinar pulmonary microvessels to hypoxia, hypercapnic acidosis, and isocapnic acidosis.
    Circulation research, 1998, Apr-06, Volume: 82, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Acidosis; Animals; Arterioles; Capillaries; Carbon Dioxide; Epoprosten

1998
Involvement of barium-sensitive K+ channels in endothelium-dependent vasodilation produced by hypercapnia in rat mesenteric vascular beds.
    British journal of pharmacology, 1998, Volume: 125, Issue:1

    Topics: Animals; Barium; Bicarbonates; Carbon Dioxide; Cytochrome P-450 Enzyme Inhibitors; Endothelium; Hydr

1998
Hypercapnic cerebral blood flow in spontaneously hypertensive rats.
    Journal of hypertension, 1998, Volume: 16, Issue:10

    Topics: Animals; Blood Flow Velocity; Cerebral Cortex; Cerebrovascular Circulation; Enzyme Inhibitors; Hyper

1998
Influence of nitrovasodilators and cyclooxygenase inhibitors on cerebral vasoreactivity in conscious rabbits.
    European journal of pharmacology, 2001, Feb-02, Volume: 412, Issue:3

    Topics: Acetazolamide; Animals; Blood Pressure; Blood Vessels; Cerebrovascular Circulation; Cyclooxygenase I

2001
Endothelial NO and prostanoid involvement in newborn and juvenile pig pial arteriolar vasomotor responses.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Age Factors; Animals; Animals, Newborn; Arterioles; Bra

2001
Chronic administration of indomethacin increases role of nitric oxide in hypercapnic cerebrovasodilation in piglets.
    Prostaglandins & other lipid mediators, 2002, Volume: 67, Issue:1

    Topics: Administration, Topical; Animals; Animals, Newborn; Blood Pressure; Brain; Cyclooxygenase Inhibitors

2002
Compensatory role of NO in cerebral circulation of piglets chronically treated with indomethacin.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:2

    Topics: Acetylcholine; Animals; Animals, Newborn; Bradykinin; Cardiovascular Agents; Cells, Cultured; Cerebr

2002
[Cerebral blood flow reactions to hypo- and hypercapnia during indomethacin inhibition of prostaglandin biosynthesis].
    Biulleten' eksperimental'noi biologii i meditsiny, 1979, Volume: 87, Issue:3

    Topics: Acid-Base Equilibrium; Animals; Carbon Dioxide; Cats; Cerebrospinal Fluid; Cerebrovascular Circulati

1979
The effect of indomethacin on the blood flow-metabolism couple in the brain under normal, hypercapnic and hypoxic conditions.
    Acta physiologica Scandinavica, 1979, Volume: 107, Issue:3

    Topics: Animals; Brain; Cerebrovascular Circulation; Hypercapnia; Hypoxia; Indomethacin; Male; Oxygen; Parti

1979
[The metabolic regulation of the retinal blood flow and the role of prostaglandins (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1978, Volume: 172, Issue:4

    Topics: Animals; Arterioles; Aspirin; Histamine; Hypercapnia; Hypoxia; Indomethacin; Prostaglandins E; Regio

1978
Studies on the role of prostaglandins in the regulation of retinal blood flow.
    Experimental eye research, 1978, Volume: 26, Issue:6

    Topics: Animals; Arterioles; Aspirin; Fluorescein Angiography; Hypercapnia; Hypoxia; Indomethacin; Prostagla

1978
Reversal by increased CSF [H+] and [K+] of phorbol ester-induced arteriolar constriction in piglets.
    The American journal of physiology, 1992, Volume: 263, Issue:5 Pt 2

    Topics: Animals; Animals, Newborn; Arterioles; Colforsin; Hydrogen; Hypercapnia; Indomethacin; Isoproterenol

1992
Effects of indomethacin on myogenic contractile activation and responses to changes in O2 and CO2 in isolated feline cerebral arteries.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:5

    Topics: Animals; Carbon Dioxide; Cats; Cerebral Arteries; Female; Hypercapnia; Hypoxia; In Vitro Techniques;

1992
Pressure ventilation increases brain vascular prostacyclin production in newborn pigs.
    Pediatric research, 1990, Volume: 28, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Brain; Cerebrovascular Circulation; Epopros

1990
Effect of indomethacin on the regulation of cerebral blood flow during respiratory alkalosis in newborn piglets.
    Pediatric research, 1989, Volume: 26, Issue:6

    Topics: Alkalosis, Respiratory; Animals; Animals, Newborn; Carbon Dioxide; Cerebrovascular Circulation; Elec

1989
Effects of indomethacin and diclofenac on cerebral blood flow in hypercapnic conscious rats.
    European journal of pharmacology, 1988, May-10, Volume: 149, Issue:3

    Topics: Animals; Carbon Dioxide; Cerebrovascular Circulation; Diclofenac; Hypercapnia; Indomethacin; Male; R

1988
Hypoxia and hypercarbia increase bronchial blood flow through bronchopulmonary anastomoses in anesthetized dogs.
    The American review of respiratory disease, 1986, Volume: 134, Issue:1

    Topics: Anesthesia, General; Animals; Arteriovenous Anastomosis; Bronchi; Bronchial Arteries; Dogs; Hypercap

1986
Indomethacin does not potentiate renovascular constriction during hypercapnia in unanesthetized rabbits.
    Prostaglandins, 1985, Volume: 30, Issue:2

    Topics: Animals; Cyclooxygenase Inhibitors; Hypercapnia; Indomethacin; Kidney; Prostaglandins; Rabbits; Regi

1985
Prostanoids in cortical subarachnoid cerebrospinal fluid and pial arterial diameter in newborn pigs.
    Circulation research, 1985, Volume: 57, Issue:5

    Topics: Animals; Animals, Newborn; Cerebral Arteries; Cisterna Magna; Female; Hypercapnia; Hypoxia, Brain; I

1985
Effects of indomethacin upon cerebral hemodynamics of newborn pigs.
    Pediatric research, 1985, Volume: 19, Issue:11

    Topics: Animals; Animals, Newborn; Blood-Brain Barrier; Cerebrovascular Circulation; Hemodynamics; Hypercapn

1985
Inhibition of prostaglandin synthesis and the response of baboon cerebral circulation to carbon dioxide.
    Nature: New biology, 1973, Oct-10, Volume: 245, Issue:145

    Topics: Animals; Brain; Cerebrovascular Circulation; Haplorhini; Hypercapnia; Indomethacin; Papio; Prostagla

1973