indomethacin has been researched along with Hypercalcemia in 70 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Hypercalcemia: Abnormally high level of calcium in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An infant presented with a non-metastatic renal spindle cell sarcoma and hypercalcaemia, which resolved after treatment with indomethacin." | 7.68 | Indomethacin responsive hypercalcaemia associated with a renal sarcoma. ( Dillon, MJ; Gibbs, J; Lang, S; Meghji, S; Pritchard, J, 1990) |
| " We therefore assessed the effect of Indomethacin and aspirin on some parameters of calcium metabolism in patients with breast cancer." | 7.65 | Failure of indomethacin to reduce hypercalcemia in patients with breast cancer. ( Bondy, PK; Coombes, RC; Neville, AM; Powles, TJ, 1976) |
| "Recombinant human TGF alpha-induced bone resorption was completely inhibited by indomethacin." | 5.29 | Ascites sarcoma 180, a tumor associated with hypercalcemia, secretes potent bone-resorbing factors including transforming growth factor alpha, interleukin-1 alpha and interleukin-6. ( Suzuki, K; Yamada, S, 1994) |
| "Hypercalcemia is a known complication of childhood malignancies but has never been reported to be associated with Langerhans cell histiocytosis (LCH) in a pediatric patient." | 5.29 | Langerhans cell histiocytosis and hypercalcemia: clinical response to indomethacin. ( McLean, TW; Pritchard, J, 1996) |
| "The hypercalcemia was unresponsive to hydration and oral phosphate." | 5.25 | Indomethacin-responsive hypercalcemia in a patient with renal-cell adenocarcinoma. ( Alexander, RW; Brereton, HD; DeVita, VT; Halushka, PV; Keiser, HR; Mason, DM, 1974) |
| " Less convincing, but suggestive evidence exists for: 1-asparaginase, iatrogenic hypercalcemia, chlorthalidine, corticosteroids, ethacrynic acid, phenformin, and procainamide." | 4.76 | Drug-induced pancreatitis: a critical review. ( Kern, F; Mallory, A, 1980) |
| "The hypothesis that endogenous PGE2 mediates defective thick ascending limb (TAL) Cl reabsorption (percent delivered load: FRCl%) in rats with vitamin D-induced chronic hypercalcemia (HC) was tested by measuring FRCl% in loop segments microperfused in vivo in HC and control rats treated acutely with indomethacin (Indo) or its vehicle, and obtaining the corresponding outer medullary [PGE2]." | 3.68 | Endogenous prostaglandin E2 mediates inhibition of rat thick ascending limb Cl reabsorption in chronic hypercalcemia. ( Borzecki, JS; McKay, AJ; Peterson, LN, 1993) |
| "An infant presented with a non-metastatic renal spindle cell sarcoma and hypercalcaemia, which resolved after treatment with indomethacin." | 3.68 | Indomethacin responsive hypercalcaemia associated with a renal sarcoma. ( Dillon, MJ; Gibbs, J; Lang, S; Meghji, S; Pritchard, J, 1990) |
| " We therefore assessed the effect of Indomethacin and aspirin on some parameters of calcium metabolism in patients with breast cancer." | 3.65 | Failure of indomethacin to reduce hypercalcemia in patients with breast cancer. ( Bondy, PK; Coombes, RC; Neville, AM; Powles, TJ, 1976) |
| "Indomethacin was effective in only one of five patients to whom it was given, and EHDP was effective also in only one of five patients." | 2.65 | Comparative study of available medical therapy for hypercalcemia of malignancy. ( Heath, DA; Mundy, GR; Wilkinson, R, 1983) |
| "Recombinant human TGF alpha-induced bone resorption was completely inhibited by indomethacin." | 1.29 | Ascites sarcoma 180, a tumor associated with hypercalcemia, secretes potent bone-resorbing factors including transforming growth factor alpha, interleukin-1 alpha and interleukin-6. ( Suzuki, K; Yamada, S, 1994) |
| "Hypercalcemia is a known complication of childhood malignancies but has never been reported to be associated with Langerhans cell histiocytosis (LCH) in a pediatric patient." | 1.29 | Langerhans cell histiocytosis and hypercalcemia: clinical response to indomethacin. ( McLean, TW; Pritchard, J, 1996) |
| "Human pancreatic cancer cells (FA-6) producing bone resorbing factor were established in culture." | 1.28 | The tumor cells (FA-6) established from a pancreatic cancer associated with humoral hypercalcemia of malignancy: a simultaneous production of parathyroid hormone-like activity and transforming growth factor activity. ( Akatsu, T; Kinoshita, T; Kosano, H; Kugai, N; Nagata, N; Shimauchi, T; Takatani, O; Ueyama, Y; Yasutomo, Y, 1989) |
| "Treatment with prednisolone (1." | 1.27 | Association of hypercalcemia with tumors producing colony-stimulating factor(s). ( Asano, S; Kondo, Y; Kosaka, K; Mori, M; Ohkawa, H; Ohsawa, N; Okabe, T; Sato, K; Sato, N; Ueyama, Y, 1983) |
| "By an autopsy, hepatocellular carcinoma was found in the right lobe of the liver." | 1.27 | Prostaglandin-E-producing hepatocellular carcinoma with hypercalcemia. ( Hasumura, Y; Ikeda, T; Takeuchi, J; Tozuka, S, 1988) |
| "Therefore, 146 trials of treatment for hypercalcemia between 1980 and 1983 at the National Cancer Center Hospital, Tokyo, were evaluated retrospectively." | 1.27 | A retrospective evaluation of the medical treatment of malignancy-associated hypercalcemia. ( Abe, K; Adachi, I; Kimura, S; Matsubara, H; Sato, Y; Suemasu, K; Suzuki, M; Yamaguchi, K, 1986) |
| "Hypercalcemia is associated with impaired urinary concentrating ability." | 1.27 | Role of the loop segment in the urinary concentrating defect of hypercalcemia. ( Booker, BB; Galla, JH; Luke, RG, 1986) |
| "Indomethacin was given to four patients with hypercalcemia with no effect on serum calcium levels in any cases." | 1.27 | Hypercalcemia of cancer in the digestive tract. ( Furuta, S; Monno, S; Nagata, A, 1987) |
| "Patients with advanced breast cancer may develop acute, severe hypercalcemia when treated with estrogens or antiestrogens." | 1.27 | Estrogens and antiestrogens stimulate release of bone resorbing activity by cultured human breast cancer cells. ( Eilon, G; Mundy, GR; Saez, S; Valentin-Opran, A, 1985) |
| "Tumor-stimulated bone resorption was blocked by indomethacin and eicosatetraynoic acid, inhibitors of the synthesis of prostaglandins (PGs) and related metabolites of arachidonic acid, whereas resorption stimulated by parathyroid hormone (PTH), PGE2, or 1,25-(OH)2D3 was not." | 1.26 | Bone resorption and humoral hypercalcemia of malignancy: stimulation of bone resorption in vitro by tumor extracts is inhibited by prostaglandin synthesis inhibitors. ( Fredericks, RS; Minkin, C; Pokress, S; Rude, RK; Sharp, CF; Singer, FR; Tong, M, 1981) |
| "Treatment with indomethacin, a potent inhibitor of prostaglandin synthesis, did not lower serum calcium concentrations with two different doses (1·6 mg/kg/day orally and 5 mg/kg/day i." | 1.26 | Prostaglandin E production and hypercalcaemia in rats bearing the Walker carcinosarcoma. ( Bonsch, G; Erlenmaier, T; Imbeck, H; Minne, HW; Mrongovius, R; Müller, H; Seyberth, HW; Strein, K, 1980) |
| "The treatment of hypercalcemia is directed toward immediate correction of the electrolyte imbalance and long-term control." | 1.26 | Genitourinary malignancy and pseudohyperparathyroidism. ( Barry, JM; Carey, TC; Metcalfe, JB, 1978) |
| "Indomethacin treatment lowered both serum calcium and the plasma level of 15-keto-13,14-dihydro-PGE2." | 1.26 | Prostaglandin-mediated hypercalcemia in the VX2 carcinoma-bearing rabbit. ( Hubbard, WC; Oates, JA; Oelz, O; Seyberth, HW; Sweetman, BJ; Watson, JT, 1977) |
| "The production of bone resorption-stimulating activity and PGE2 by VX2 cells in culture were both inhibited by indomethacin (100 ng/ml)." | 1.25 | Hypercalcemia and tumor-prostaglandins: the VX2 carcinoma model in the rabbit. ( Franklin, R; Levine, L; Tashjian, AH; Voelkel, EF; Wasserman, E, 1975) |
| "The specific bone resorption-stimulating activity of the HSDM(1) factor extracted from the tumor is high and approximately equal to that of PGE(2) as measured in a bone tissue culture system in vitro." | 1.25 | Evidence that the bone resorption-stimulating factor produced by mouse fibrosarcoma cells is prostaglandin E 2 . A new model for the hypercalcemia of cancer. ( Goldhaber, P; Levine, L; Tashjian, AH; Voelkel, EF, 1972) |
| "The hypercalcemia was unresponsive to hydration and oral phosphate." | 1.25 | Indomethacin-responsive hypercalcemia in a patient with renal-cell adenocarcinoma. ( Alexander, RW; Brereton, HD; DeVita, VT; Halushka, PV; Keiser, HR; Mason, DM, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (90.00) | 18.7374 |
| 1990's | 5 (7.14) | 18.2507 |
| 2000's | 1 (1.43) | 29.6817 |
| 2010's | 1 (1.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pacifici, GM | 1 |
| Diament, MJ | 1 |
| Peluffo, GD | 1 |
| Stillitani, I | 1 |
| Cerchietti, LC | 1 |
| Navigante, A | 1 |
| Ranuncolo, SM | 1 |
| Klein, SM | 1 |
| Doppelt, SH | 1 |
| Slovik, DM | 1 |
| Neer, RM | 1 |
| Nolan, J | 1 |
| Zusman, RM | 1 |
| Potts, JT | 3 |
| Mundy, GR | 3 |
| Wilkinson, R | 1 |
| Heath, DA | 1 |
| Gennari, C | 1 |
| Montagnani, M | 1 |
| Nami, R | 1 |
| Francini, G | 1 |
| Elliott, GT | 1 |
| McKenzie, MW | 1 |
| Levi, M | 2 |
| Ellis, MA | 1 |
| Berl, T | 2 |
| Kukreja, SC | 1 |
| Schürer, CC | 1 |
| Peters, U | 1 |
| Fischer, JT | 1 |
| Peterson, L | 1 |
| Kondo, Y | 2 |
| Sato, K | 4 |
| Ohkawa, H | 2 |
| Ueyama, Y | 3 |
| Okabe, T | 2 |
| Sato, N | 1 |
| Asano, S | 1 |
| Mori, M | 1 |
| Ohsawa, N | 2 |
| Kosaka, K | 1 |
| Ritchie, GA | 1 |
| Heath, H | 2 |
| Weller, RE | 1 |
| Minkin, C | 1 |
| Fredericks, RS | 1 |
| Pokress, S | 1 |
| Rude, RK | 1 |
| Sharp, CF | 1 |
| Tong, M | 1 |
| Singer, FR | 1 |
| Serros, ER | 1 |
| Kirschenbaum, MA | 1 |
| Takeuchi, T | 1 |
| Takeuchi, H | 1 |
| Hoshino, R | 1 |
| Ohmi, K | 1 |
| Mallory, A | 1 |
| Kern, F | 1 |
| Brenner, DE | 1 |
| Harvey, HA | 1 |
| Lipton, A | 1 |
| Demers, L | 1 |
| Josse, RG | 1 |
| Wilson, DR | 1 |
| Heersche, JN | 1 |
| Mills, JR | 1 |
| Murray, TM | 1 |
| Seyberth, HW | 5 |
| Bonsch, G | 1 |
| Müller, H | 1 |
| Minne, HW | 1 |
| Erlenmaier, T | 1 |
| Strein, K | 1 |
| Imbeck, H | 1 |
| Mrongovius, R | 1 |
| Suzuki, K | 1 |
| Yamada, S | 1 |
| Lozance, LA | 1 |
| Zafirovska, KG | 1 |
| Bogdanovska, SV | 1 |
| Zafirovski, GJ | 1 |
| Peterson, LN | 1 |
| McKay, AJ | 1 |
| Borzecki, JS | 1 |
| McLean, TW | 1 |
| Pritchard, J | 2 |
| Blum, I | 1 |
| Dindogru, A | 1 |
| Gailani, S | 1 |
| Henderson, ES | 1 |
| Wallace, HJ | 1 |
| Fitzpatrick, J | 1 |
| Benvenisti, D | 1 |
| Goldberg, H | 1 |
| Sturtridge, WC | 1 |
| Segre, GV | 3 |
| Hamet, P | 1 |
| Sweetman, BJ | 3 |
| Oates, JA | 4 |
| Jaffe, BM | 2 |
| Kopen, DF | 1 |
| DeSchryver-Kecskemeti, K | 1 |
| Gingerich, RL | 1 |
| Greider, M | 1 |
| Godeau, P | 1 |
| Wechsler, B | 1 |
| Lambrozo, J | 1 |
| Raisz, LG | 1 |
| Morita, R | 1 |
| Metcalfe, JB | 1 |
| Carey, TC | 1 |
| Barry, JM | 1 |
| Pina Boronat, R | 1 |
| Buzón Rueda, JL | 1 |
| Arenas Mirave, JI | 1 |
| Boixeda Miquel, D | 1 |
| Hernández Ranz, F | 1 |
| Moreira Vicente, V | 1 |
| Rodríguez San Pedro, F | 1 |
| Gaskin, KJ | 1 |
| Vines, RH | 1 |
| Tashjian, AH | 6 |
| Voelkel, EF | 5 |
| Levine, L | 5 |
| Hubbard, WC | 1 |
| Oelz, O | 1 |
| Watson, JT | 1 |
| Robertson, RP | 2 |
| Baylink, DJ | 2 |
| Metz, SA | 1 |
| Cummings, KB | 1 |
| Coombes, RC | 1 |
| Neville, AM | 2 |
| Bondy, PK | 1 |
| Powles, TJ | 2 |
| Franklin, R | 1 |
| Wasserman, E | 1 |
| Marini, BJ | 1 |
| Adkison, HW | 1 |
| Ito, H | 1 |
| Sanada, T | 1 |
| Katayama, T | 1 |
| Shimazaki, J | 1 |
| Morgan, JL | 1 |
| Gibbs, J | 1 |
| Dillon, MJ | 1 |
| Lang, S | 1 |
| Meghji, S | 1 |
| Chasan, SA | 1 |
| Pothel, LR | 1 |
| Huben, RP | 1 |
| Nagata, N | 1 |
| Akatsu, T | 1 |
| Kugai, N | 1 |
| Yasutomo, Y | 1 |
| Kinoshita, T | 1 |
| Kosano, H | 1 |
| Shimauchi, T | 1 |
| Takatani, O | 1 |
| Ikeda, T | 1 |
| Tozuka, S | 1 |
| Hasumura, Y | 1 |
| Takeuchi, J | 1 |
| Kimura, S | 2 |
| Sato, Y | 1 |
| Matsubara, H | 1 |
| Adachi, I | 1 |
| Yamaguchi, K | 1 |
| Suzuki, M | 1 |
| Suemasu, K | 1 |
| Abe, K | 1 |
| Bringhurst, FR | 1 |
| Bierer, BE | 1 |
| Godeau, F | 1 |
| Neyhard, N | 1 |
| Varner, V | 1 |
| Fujii, Y | 2 |
| Kasono, K | 1 |
| Tsushima, T | 2 |
| Shizume, K | 2 |
| Mimura, H | 1 |
| Han, DC | 1 |
| Kakiuchi, T | 1 |
| Galla, JH | 1 |
| Booker, BB | 1 |
| Luke, RG | 1 |
| Ono, M | 1 |
| Nomura, H | 1 |
| Monno, S | 1 |
| Nagata, A | 1 |
| Furuta, S | 1 |
| Masa Jiménez, JF | 1 |
| Verea Hernando, H | 1 |
| Montero Martínez, C | 1 |
| Fontán Bueso, JM | 1 |
| Gavras, I | 1 |
| Hatinoglou, S | 1 |
| Benetos, A | 1 |
| Gavras, H | 1 |
| Valentin-Opran, A | 1 |
| Eilon, G | 1 |
| Saez, S | 1 |
| Law, WM | 1 |
| Uchida, T | 1 |
| Kuwao, S | 1 |
| Ishibashi, A | 1 |
| Koshiba, K | 1 |
| Goldhaber, P | 3 |
| Clark, SA | 1 |
| Easty, DM | 1 |
| Easty, GC | 1 |
| Brereton, HD | 1 |
| Halushka, PV | 1 |
| Alexander, RW | 1 |
| Mason, DM | 1 |
| Keiser, HR | 1 |
| DeVita, VT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I Pilot Trial to Study the Safety and Efficacy of Concomitant Radiotherapy and Zoledronic Acid for the Palliation of Bone Metastases From Breast Cancer, Prostate Cancer and Lung Cancer[NCT00264420] | Phase 1 | 4 participants (Actual) | Interventional | 2005-12-31 | Completed | ||
| A Pilot Study of Immunoregulatory Factor Expression and Immune Responses in Patients With Squamous Cell Carcinoma or Papilloma of the Upper Aerodigestive Tract[NCT00001603] | 93 participants | Observational | 1996-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for indomethacin and Hypercalcemia
| Article | Year |
|---|---|
Clinical pharmacology of the loop diuretics furosemide and bumetanide in neonates and infants.
Topics: Acetazolamide; Bumetanide; Drug Therapy, Combination; Ductus Arteriosus, Patent; Extracorporeal Memb | 2012 |
Treatment of hypercalcemia.
Topics: Calcium; Chelating Agents; Diuresis; Diuretics; Female; Humans; Hypercalcemia; Indomethacin; Male; M | 1983 |
Drug-induced pancreatitis: a critical review.
Topics: Acetaminophen; Adrenal Cortex Hormones; Amphetamines; Asparaginase; Azathioprine; Chlorthalidone; Ch | 1980 |
Prostaglandins and hypercalcemic states.
Topics: Adenocarcinoma; Animals; Bone and Bones; Bone Resorption; Humans; Hypercalcemia; Indomethacin; Kidne | 1978 |
Prostaglandins and cancer: an update.
Topics: Animals; Aspirin; Bucladesine; Calcium; Carcinoma; Cell Division; Cell Line; Depression, Chemical; H | 1974 |
1 trial available for indomethacin and Hypercalcemia
| Article | Year |
|---|---|
Comparative study of available medical therapy for hypercalcemia of malignancy.
Topics: Administration, Oral; Adult; Aged; Calcium; Clinical Trials as Topic; Diphosphonates; Etidronic Acid | 1983 |
64 other studies available for indomethacin and Hypercalcemia
| Article | Year |
|---|---|
Inhibition of tumor progression and paraneoplastic syndrome development in a murine lung adenocarcinoma by medroxyprogesterone acetate and indomethacin.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Hormonal; A | 2006 |
Gut-mediated hypercalcemia in rabbits bearing VX2 carcinoma: new mechanism for tumor-induced hypercalcemia.
Topics: Animals; Carcinoma; Clodronic Acid; Hypercalcemia; Indomethacin; Male; Neoplasms, Experimental; Pros | 1982 |
[Humoral mechanisms in neoplastic hypercalcemia].
Topics: Calcitonin; Calcium; Cyclic AMP; Humans; Hypercalcemia; Indomethacin; Neoplasms; Parathyroid Hormone | 1984 |
Control of renal hemodynamics and glomerular filtration rate in chronic hypercalcemia. Role of prostaglandins, renin-angiotensin system, and calcium.
Topics: Angiotensin II; Animals; Calcium; Captopril; Glomerular Filtration Rate; Hemodynamics; Hypercalcemia | 1983 |
Diagnosis and management of hypercalcemia.
Topics: Calcitonin; Glucocorticoids; Humans; Hypercalcemia; Hyperparathyroidism; Indomethacin; Neoplasms; Ph | 1980 |
[Hypercalcemia in non-parathyroid malignant tumors].
Topics: Adrenal Cortex Hormones; Bone Neoplasms; Diuretics; Humans; Hypercalcemia; Indomethacin; Neoplasms; | 1981 |
[Therapeutic possibilities in paraneoplastic hypercalcemia].
Topics: Adrenal Cortex Hormones; Adult; Aged; Calcitonin; Diphosphonates; Drug Therapy, Combination; Female; | 1981 |
Mechanism of concentrating defect in hypercalcemia. Role of polydipsia and prostaglandins.
Topics: Animals; Body Water; Dinoprostone; Drinking; Glomerular Filtration Rate; Hypercalcemia; Indomethacin | 1983 |
Association of hypercalcemia with tumors producing colony-stimulating factor(s).
Topics: Adult; Animals; Calcium; Carcinoma, Squamous Cell; Colony-Stimulating Factors; Female; Granulocytes; | 1983 |
The direct inhibition of prostaglandin synthetase of human breast cancer tumor tissue by tamoxifen.
Topics: Bone Neoplasms; Bone Resorption; Breast Neoplasms; Cyclooxygenase Inhibitors; Dose-Response Relation | 1980 |
Canine lymphosarcoma: a model for study of the hypercalcemia of cancer.
Topics: Animals; Antineoplastic Agents; Aspirin; Bone Resorption; Calcium; Disease Models, Animal; Dog Disea | 1980 |
Bone resorption and humoral hypercalcemia of malignancy: stimulation of bone resorption in vitro by tumor extracts is inhibited by prostaglandin synthesis inhibitors.
Topics: Adult; Animals; Arachidonic Acid; Arachidonic Acids; Biological Assay; Bone and Bones; Bone Resorpti | 1981 |
Prostaglandin-dependent polyuria in hypercalcemia.
Topics: Animals; Calcitriol; Female; Hypercalcemia; Indomethacin; Kidney; Polyuria; Prostaglandins; Prostagl | 1981 |
Rhabdomyosarcoma-induced hypercalcemia in a nude mouse.
Topics: Animals; Anus Neoplasms; Calcium; Dinoprostone; Female; Humans; Hypercalcemia; Indomethacin; Mice; M | 1982 |
A study of prostaglandin E2, parathormone, and response to indomethacin in patients with hypercalcemia of malignancy.
Topics: Humans; Hypercalcemia; Indomethacin; Neoplasms; Parathyroid Hormone; Prospective Studies; Prostaglan | 1982 |
Hypercalcemia with ovarian carcinoma: evidence of a pathogenetic role for prostaglandins.
Topics: Aged; Animals; Biological Assay; Bone Resorption; Cystadenocarcinoma; Female; Humans; Hypercalcemia; | 1981 |
Prostaglandin E production and hypercalcaemia in rats bearing the Walker carcinosarcoma.
Topics: Animals; Calcium; Carcinoma 256, Walker; Dexamethasone; Female; Hypercalcemia; Indomethacin; Parathy | 1980 |
Ascites sarcoma 180, a tumor associated with hypercalcemia, secretes potent bone-resorbing factors including transforming growth factor alpha, interleukin-1 alpha and interleukin-6.
Topics: Animals; Antibodies; Blotting, Northern; Bone Resorption; Culture Media, Conditioned; Cyclic AMP; Di | 1994 |
Primary disseminated form of Ewing sarcoma in association with hypercalcemia and acute renal failure.
Topics: Acute Kidney Injury; Adult; Glomerular Filtration Rate; Humans; Hypercalcemia; Hyperparathyroidism, | 1994 |
Endogenous prostaglandin E2 mediates inhibition of rat thick ascending limb Cl reabsorption in chronic hypercalcemia.
Topics: Alkaloids; Animals; Biological Transport, Active; Chlorides; Chronic Disease; Colforsin; Cyclic AMP; | 1993 |
Langerhans cell histiocytosis and hypercalcemia: clinical response to indomethacin.
Topics: Cyclooxygenase Inhibitors; Fatal Outcome; Follow-Up Studies; Histiocytosis, Langerhans-Cell; Humans; | 1996 |
Letter: Indomethacin in hypercalcaemia.
Topics: Administration, Oral; Calcium; Humans; Hypercalcemia; Indomethacin; Time Factors | 1975 |
Letter: Indomethacin in hypercalcaemia.
Topics: Adenocarcinoma; Calcium; Humans; Hypercalcemia; Indomethacin; Kidney Neoplasms; Multiple Myeloma | 1975 |
Letter: Prostaglandins, indomethacin and hypercalcemia in neoplastic disease.
Topics: Aged; Carcinoma, Squamous Cell; Humans; Hypercalcemia; Indomethacin; Liver Neoplasms; Lung Neoplasms | 1975 |
Pharmacology and therapeutics of bone.
Topics: Animals; Bone Resorption; Calcitonin; Calcium; Cyclic AMP; Endotoxins; Glucocorticoids; Humans; Hydr | 1975 |
Characterization of the group of patients with the hypercalcemia of cancer who respond to treatment with prostaglandin synthesis inhibitors.
Topics: Aspirin; Calcium; Cyclic AMP; Humans; Hypercalcemia; Hyperparathyroidism; Indomethacin; Neoplasm Met | 1976 |
Indomethacin-responsive pancreatic cholera.
Topics: Adenoma, Islet Cell; Aged; Dehydration; Diarrhea; Female; Gastrins; Humans; Hypercalcemia; Hypokalem | 1977 |
[Treatment of hypercalcemia].
Topics: Calcitonin; Furosemide; Humans; Hypercalcemia; Indomethacin; Peritoneal Dialysis; Phosphates; Plicam | 1977 |
[Indomethacin loading test].
Topics: Calcium; Humans; Hypercalcemia; Indomethacin; Neoplasms; Prostaglandins | 1979 |
Genitourinary malignancy and pseudohyperparathyroidism.
Topics: Carcinoma, Squamous Cell; Castration; Dysgerminoma; Female; Furosemide; Humans; Hypercalcemia; Hyper | 1978 |
[Response to the administration of indomethacin in a case of paraneoplastic hypercalcemia].
Topics: Aged; Carcinoma, Squamous Cell; Dexamethasone; Drug Evaluation; Humans; Hypercalcemia; Indomethacin; | 1977 |
Hypercalcaemia: an unusual complication of tuberculosis. A case report.
Topics: Child; Humans; Hypercalcemia; Indomethacin; Male; Tuberculosis, Lymph Node | 1978 |
Plasma concentrations of 13,14-dihydro-15-keto-prostaglandin E2 in rabbits bearing the VX2 carcinoma: effects of hydrocortisone and indomethacin.
Topics: Animals; Calcium; Hydrocortisone; Hypercalcemia; Indomethacin; Neoplasms, Experimental; Prostaglandi | 1977 |
Prostaglandin-mediated hypercalcemia in the VX2 carcinoma-bearing rabbit.
Topics: Animals; Arachidonic Acids; Blood Urea Nitrogen; Creatinine; Hypercalcemia; Indomethacin; Liver; Lun | 1977 |
Plasma prostaglandin E in patients with cancer with and without hypercalcemia.
Topics: Bone Neoplasms; Female; Humans; Hypercalcemia; Indomethacin; Male; Neoplasm Metastasis; Neoplasms; P | 1976 |
Failure of indomethacin to reduce hypercalcemia in patients with breast cancer.
Topics: Aspirin; Bone Neoplasms; Breast Neoplasms; Calcium; Creatinine; Female; Humans; Hydroxyproline; Hype | 1976 |
Hypercalcemia and tumor-prostaglandins: the VX2 carcinoma model in the rabbit.
Topics: Animals; Biological Assay; Bone Resorption; Carcinoma; Disease Models, Animal; Femoral Vein; Hyperca | 1975 |
Elevated prostaglandins and suppressed parathyroid hormone associated with hypercalcemia and renal cell carcinoma.
Topics: Adenocarcinoma; Calcium; Humans; Hypercalcemia; Indomethacin; Kidney Cortex; Liver; Liver Neoplasms; | 1975 |
Letter: Indomethacin-responsive hypercalcemia.
Topics: Adenocarcinoma; Humans; Hypercalcemia; Indomethacin; Kidney Neoplasms; Male; Middle Aged | 1975 |
Prostaglandins as mediators of hypercalcemia associated with certain types of cancer.
Topics: Aspirin; Calcium; Humans; Hypercalcemia; Indomethacin; Male; Middle Aged; Neoplasms; Parathyroid Hor | 1975 |
Editorial: Prostaglandins, hypercalcemia and cancer.
Topics: Animals; Aspirin; Humans; Hypercalcemia; Indomethacin; Mice; Neoplasms; Prostaglandin Antagonists; P | 1975 |
Indomethacin responsive hypercalcaemia associated with a renal sarcoma.
Topics: Combined Modality Therapy; Dinoprostone; Humans; Hypercalcemia; Indomethacin; Infant; Kidney Neoplas | 1990 |
Management and prognostic significance of hypercalcemia in renal cell carcinoma.
Topics: Calcitonin; Calcium; Carcinoma, Renal Cell; Furosemide; Humans; Hypercalcemia; Indomethacin; Kidney | 1989 |
The tumor cells (FA-6) established from a pancreatic cancer associated with humoral hypercalcemia of malignancy: a simultaneous production of parathyroid hormone-like activity and transforming growth factor activity.
Topics: Animals; Biological Assay; Bone and Bones; Bone Resorption; Chromatography, Gel; Culture Media; Cycl | 1989 |
Prostaglandin-E-producing hepatocellular carcinoma with hypercalcemia.
Topics: Aged; Carcinoma, Hepatocellular; Humans; Hypercalcemia; Indomethacin; Liver Neoplasms; Male; Phospha | 1988 |
[Hypercalcemia].
Topics: Calcitonin; Humans; Hypercalcemia; Indomethacin; Paraneoplastic Syndromes; Prednisolone | 1989 |
A retrospective evaluation of the medical treatment of malignancy-associated hypercalcemia.
Topics: Adult; Aged; Calcitonin; Calcium; Female; Fluid Therapy; Glucocorticoids; Humans; Hypercalcemia; Ind | 1986 |
Humoral hypercalcemia of malignancy. Release of a prostaglandin-stimulating bone-resorbing factor in vitro by human transitional-cell carcinoma cells.
Topics: Animals; Biological Assay; Biological Products; Bone Resorption; Calcitonin; Carcinoma, Transitional | 1986 |
Production of interleukin-1 alpha and a parathyroid hormone-like factor by a squamous cell carcinoma of the esophagus (EC-GI) derived from a patient with hypercalcemia.
Topics: Aged; Animals; Bone Resorption; Carcinoma, Squamous Cell; Chromatography; DNA; Esophageal Neoplasms; | 1988 |
Production of bone-resorbing activity and colony-stimulating activity in vivo and in vitro by a human squamous cell carcinoma associated with hypercalcemia and leukocytosis.
Topics: Animals; Bone Resorption; Carcinoma, Squamous Cell; Chromatography, Gel; Colony-Stimulating Factors; | 1986 |
Role of the loop segment in the urinary concentrating defect of hypercalcemia.
Topics: Animals; Biological Transport, Active; Calcium; Calcium Gluconate; Chlorides; Ergocalciferols; Hyper | 1986 |
Production of interleukin 1 alpha-like factor and colony-stimulating factor by a squamous cell carcinoma of the thyroid (T3M-5) derived from a patient with hypercalcemia and leukocytosis.
Topics: Aged; Bone Resorption; Carcinoma, Squamous Cell; Chromatography, Ion Exchange; Colony-Stimulating Fa | 1987 |
Hypercalcemia of cancer in the digestive tract.
Topics: Aged; Aged, 80 and over; Bone Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Hypercalcemia; | 1987 |
[Indomethacin treatment of hypercalcemia associated with pulmonary adenocarcinoma].
Topics: Humans; Hypercalcemia; Indomethacin; Lung Neoplasms; Male; Middle Aged | 1986 |
Calcium stimulates vasopressin release.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Calcium; Hypercalcemia; Hypertension; Indomethacin; K | 1986 |
Estrogens and antiestrogens stimulate release of bone resorbing activity by cultured human breast cancer cells.
Topics: Biological Products; Bone Resorption; Breast Neoplasms; Cells, Cultured; Cytokines; Dinoprostone; Es | 1985 |
Familial benign hypercalcemia (hypocalciuric hypercalcemia). Clinical and pathogenetic studies in 21 families.
Topics: Adolescent; Adult; Aged; Bone and Bones; Calcium; Female; Humans; Hypercalcemia; Indomethacin; Intes | 1985 |
Elevated prostaglandin and indomethacin-responsive hypercalcemia in a patient with malignant pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Bone Neoplasms; Calcium; Humans; Hypercalcemia; Indomethacin; Male; Middle | 1985 |
Prostaglandins, calcium metabolism and cancer.
Topics: Animals; Aspirin; Bone and Bones; Bone Resorption; Calcium; Calcium Radioisotopes; Cells, Cultured; | 1974 |
Evidence that the bone resorption-stimulating factor produced by mouse fibrosarcoma cells is prostaglandin E 2 . A new model for the hypercalcemia of cancer.
Topics: Animals; Bone Neoplasms; Bone Resorption; Calcium; Cells, Cultured; Clone Cells; Culture Techniques; | 1972 |
Letter: Indomethacin, prostaglandin and hypercalcemia.
Topics: Alcohol Oxidoreductases; Cyclic AMP; Humans; Hypercalcemia; Indomethacin; Mixed Function Oxygenases; | 1974 |
Successful treatment of hypercalcemia by indomethacin in mice bearing a prostaglandin-producing fibrosarcoma.
Topics: Administration, Oral; Animals; Biological Assay; Body Weight; Bone Resorption; Calcium; Calcium Isot | 1973 |
The inhibition by aspirin and indomethacin of osteolytic tumor deposits and hypercalcaemia in rats with Walker tumour, and its possible application to human breast cancer.
Topics: Animals; Aspirin; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Calciu | 1973 |
Indomethacin-responsive hypercalcemia in a patient with renal-cell adenocarcinoma.
Topics: Adenocarcinoma; Administration, Oral; Calcium; Humans; Hypercalcemia; Indomethacin; Kidney Neoplasms | 1974 |