indomethacin has been researched along with Hodgkin Disease in 42 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Hodgkin Disease: A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In one patient with untreated Hodgkin's disease, temperature fell from 40." | 5.27 | Antipyretic effect of indomethacin in malignant lymphoma. ( Björkholm, M; Engervall, P; Grimfors, G; Holm, G, 1986) |
| "When indomethacin was added in vitro, lymphocytes from healthy controls showed similar but more consistent increases of PHA responses than lymphocytes from patients with sarcoidosis or lymphoma." | 5.27 | The effect of indomethacin treatment on lymphocyte PHA reactivity in healthy controls and patients with lymphoma and sarcoidosis. ( Underhill, G; Valdimarsson, H, 1985) |
| "In one patient with untreated Hodgkin's disease, temperature fell from 40." | 1.27 | Antipyretic effect of indomethacin in malignant lymphoma. ( Björkholm, M; Engervall, P; Grimfors, G; Holm, G, 1986) |
| "A 52-year-old man developed minimal change nephrotic syndrome which responded only partially to prednisolone." | 1.27 | Nephrotic syndrome preceding Hodgkin's disease by 42 months. ( de Jong, PE; de Zeeuw, D; Huisman, RM; van der Hem, GK; van Imhoff, GW, 1986) |
| "Patients with active Hodgkin's disease (HD) often demonstrate an impaired T-cell proliferative response to phytohemagglutinin (PHA)." | 1.27 | Impaired interleukin regulation of the phytohemagglutinin response in Hodgkin's disease. ( Comis, RL; Paolozzi, FP; Poiesz, BJ; Reeves, WG; Tomar, RH; Zamkoff, KW, 1985) |
| "Patients with active Hodgkin's disease demonstrate a significant depression of cellular immunity." | 1.27 | [Abnormal regulation in the production of IL2 in Hodgkin's disease]. ( Chouaib, S; Ferme, C; Fradelizi, D; Janvier, M; Kaplan, C; Marchiol, C; Muller, JY, 1985) |
| "When indomethacin was added in vitro, lymphocytes from healthy controls showed similar but more consistent increases of PHA responses than lymphocytes from patients with sarcoidosis or lymphoma." | 1.27 | The effect of indomethacin treatment on lymphocyte PHA reactivity in healthy controls and patients with lymphoma and sarcoidosis. ( Underhill, G; Valdimarsson, H, 1985) |
| "When indomethacin was added to the cultures, the mean percent increase in patient proliferation exceeded that of normals (160 +/- 19% vs 81 +/- 9%; p less than 0." | 1.26 | Depressed T cell proliferative responses in Hodgkin's disease: role of monocyte-mediated suppression via prostaglandins and hydrogen peroxide. ( Bostick-Bruton, F; Fisher, RI, 1982) |
| "With indomethacin it was 94% of the control value." | 1.26 | Prostaglandin-producing suppressor cells in Hodgkin's disease. ( Bankhurst, AD; Goodwin, JS; Messner, RP; Peake, GT; Saiki, JH; Williams, RC, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haim, N | 1 |
| Meidav, A | 1 |
| Samuelly, B | 1 |
| Segal, R | 1 |
| Mekori, T | 1 |
| Robinson, E | 1 |
| Fisher, RI | 4 |
| Vanhaelen, C | 1 |
| Bostick, F | 1 |
| Vanhaelen, CP | 1 |
| Passwell, J | 1 |
| Levanon, M | 1 |
| Davidsohn, J | 1 |
| Ramot, B | 2 |
| Han, T | 1 |
| Winnicki, MS | 1 |
| Bostick-Bruton, F | 1 |
| Rosenthal, E | 1 |
| Biniaminov, M | 1 |
| Ben-Bassat, I | 1 |
| Jondal, M | 1 |
| Merrill, J | 1 |
| Ullberg, M | 1 |
| Deshazo, RD | 2 |
| Ewel, C | 1 |
| Londono, S | 1 |
| Metzger, Z | 1 |
| Hoffeld, JT | 1 |
| Oppenheim, JJ | 3 |
| Pees, HW | 1 |
| Girmann, G | 1 |
| Schwamborn, J | 1 |
| Amlot, PL | 1 |
| Chivers, A | 1 |
| Heinzelmann, D | 1 |
| Youlten, LJ | 1 |
| Engleman, EG | 1 |
| Benike, C | 1 |
| Hoppe, RT | 1 |
| Kaplan, HS | 1 |
| Schechter, GP | 1 |
| Wahl, LM | 1 |
| Sibbitt, WL | 1 |
| Bankhurst, AD | 2 |
| Williams, RC | 2 |
| Goodwin, JS | 1 |
| Messner, RP | 1 |
| Peake, GT | 1 |
| Saiki, JH | 1 |
| Hansz, J | 1 |
| Sawiński, K | 1 |
| Minassian, AA | 1 |
| Villa, ML | 1 |
| Colleoni, M | 1 |
| Valenti, F | 1 |
| Tondini, C | 1 |
| Clerici, E | 1 |
| Nagai, H | 1 |
| Cossman, J | 1 |
| Engervall, P | 1 |
| Björkholm, M | 1 |
| Grimfors, G | 1 |
| Holm, G | 1 |
| Musatti, CC | 1 |
| Yasaka, K | 1 |
| Santos, LM | 1 |
| Huisman, RM | 1 |
| de Jong, PE | 1 |
| de Zeeuw, D | 1 |
| van Imhoff, GW | 1 |
| van der Hem, GK | 1 |
| Soulillou, JP | 1 |
| Douillard, JY | 1 |
| Vie, H | 1 |
| Harousseau, JL | 1 |
| Guenel, J | 1 |
| le Mevel-le Pourhiet, A | 1 |
| le Mevel, B | 1 |
| Estevez, ME | 1 |
| Ballart, IJ | 1 |
| Diez, RA | 1 |
| Sen, L | 1 |
| Nicastro, MA | 1 |
| Wechsler, A | 1 |
| Zamkoff, KW | 1 |
| Reeves, WG | 1 |
| Paolozzi, FP | 1 |
| Poiesz, BJ | 1 |
| Comis, RL | 1 |
| Tomar, RH | 1 |
| Marchiol, C | 1 |
| Kaplan, C | 1 |
| Chouaib, S | 1 |
| Janvier, M | 1 |
| Ferme, C | 1 |
| Muller, JY | 1 |
| Fradelizi, D | 1 |
| Underhill, G | 1 |
| Valdimarsson, H | 1 |
| Simon, S | 1 |
| Azevedo, SJ | 1 |
| Byrnes, JJ | 1 |
| Kiely, JM | 1 |
| Banerjee, AK | 1 |
| Lusch, CJ | 1 |
| Serpick, AA | 1 |
| Slater, L | 1 |
| Milevskaia, IuL | 1 |
| Treske, U | 2 |
| Marcolongo, R | 2 |
| Bianco, G | 1 |
| Di Paolo, N | 1 |
| Bravi, A | 1 |
| Hiemeyer, V | 2 |
| Fusco, FA | 1 |
| Azzolini, A | 1 |
| Dolcino, G | 1 |
| Feyen, H | 1 |
| Pötting, H | 1 |
| Liotta, S | 1 |
| Ronchi, F | 1 |
| Silberman, HR | 1 |
| McGinn, TG | 1 |
| Kremer, WB | 1 |
| Boggiano, CA | 1 |
1 review available for indomethacin and Hodgkin Disease
| Article | Year |
|---|---|
Suppressor monocytes in human disease: a review.
Topics: Cell Communication; Hodgkin Disease; Humans; Immunity; Immunoglobulins; Immunologic Deficiency Syndr | 1979 |
41 other studies available for indomethacin and Hodgkin Disease
| Article | Year |
|---|---|
Prostaglandin-related and adherent cell suppressor system in apparently cured Hodgkin's disease patients.
Topics: Adolescent; Adult; Aged; Cell Adhesion; Female; Hodgkin Disease; Humans; Indomethacin; Lung Neoplasm | 1984 |
Increased sensitivity to normal adherent suppressor cells in untreated advanced Hodgkin's disease.
Topics: Adult; Aged; Cell Adhesion; Female; Freezing; Hodgkin Disease; Humans; Indomethacin; Lymphocyte Cult | 1981 |
Increased sensitivity of lymphocytes from patients with Hodgkin's disease to concanavalin A-induced suppressor cells.
Topics: Adolescent; Adult; Cell Adhesion; Concanavalin A; Female; Hodgkin Disease; Humans; Indomethacin; Lym | 1981 |
Monocyte PGE2 secretion in Hodgkin's disease and its relation to decreased cellular immunity.
Topics: Adolescent; Adult; Cell Division; Cells, Cultured; Child; Dinoprostone; Dose-Response Relationship, | 1983 |
Indomethacin-mediated enhancement of lymphocyte response to mitogens; in treated and untreated Hodgkin's disease and non-Hodgkin's lymphoma.
Topics: Adult; Aged; Female; Hodgkin Disease; Humans; Indomethacin; Interleukin-2; Lymphocyte Activation; Ly | 1980 |
Depressed T cell proliferative responses in Hodgkin's disease: role of monocyte-mediated suppression via prostaglandins and hydrogen peroxide.
Topics: Catalase; Hodgkin Disease; Humans; Hydrogen Peroxide; Immune Tolerance; Indomethacin; Lymphocyte Act | 1982 |
Effect of levamisole, thymic humoral factor and indomethacin on e-rosette formation of lymphocytes in Hodgkin's disease.
Topics: Hodgkin Disease; Humans; Indomethacin; Levamisole; Lymphocytes; Monocytes; Rosette Formation; Thymic | 1981 |
Monocyte-induced human natural killer cell suppression followed by increased cytotoxic activity during short-term in vitro culture in autologous serum.
Topics: Cell Communication; Cells, Cultured; Depression, Chemical; Hodgkin Disease; Humans; Immunosuppressio | 1981 |
Evidence for the involvement of monocyte-derived toxic oxygen metabolites in the lymphocyte dysfunction of Hodgkin's disease.
Topics: Adolescent; Adult; Antioxidants; Catalase; Hodgkin Disease; Humans; Indomethacin; Leukocyte Count; L | 1981 |
[The influence on PHA-stimulation by inhibition of prostaglandin synthesis in vitro in patients with Hodgkin's disease (author's transl)].
Topics: Adolescent; Adult; Hodgkin Disease; Humans; Indomethacin; Lymphocyte Activation; Middle Aged; Phytoh | 1980 |
Increased prostaglandin synthesis in Hodgkin's disease: a lymphocyte-monocyte interaction.
Topics: Cell Adhesion; Hodgkin Disease; Humans; Indomethacin; Lymphocytes; Monocytes; Phagocytosis; Prostagl | 1980 |
Indomethacin-responsive mononuclear cell dysfunction in Hodgkins disease.
Topics: Hodgkin Disease; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Indomethacin; Lymphocyte Act | 1980 |
Suppressor cells of the mixed lymphocyte reaction in patients with Hodgkin's disease.
Topics: HLA Antigens; Hodgkin Disease; Humans; Immunity, Cellular; Indomethacin; Lymphocyte Culture Test, Mi | 1979 |
Studies of cell subpopulations mediating mitogen hyporesponsiveness in patients with Hodgkin's disease.
Topics: Hodgkin Disease; Humans; Immune Adherence Reaction; Immunity, Cellular; In Vitro Techniques; Indomet | 1978 |
Prostaglandin-producing suppressor cells in Hodgkin's disease.
Topics: Adult; Cell Adhesion; Cyclooxygenase Inhibitors; Female; Hodgkin Disease; Humans; Immunosuppression | 1977 |
Splenic monocyte-macrophage dependent suppression of autologous granulocyte-progenitors growth in Hodgkin's disease.
Topics: Adult; Bone Marrow; Colony-Forming Units Assay; Female; Granulocytes; Growth Inhibitors; Hematopoiet | 1987 |
Suppressor cells in the peripheral blood and spleen of patients with Hodgkin's disease.
Topics: Adolescent; Adult; Cells, Cultured; DNA; Female; Hodgkin Disease; Humans; Indomethacin; Male; Middle | 1986 |
[Antibody response in cultures of lymphocytes from patients with Hodgkin's lymphoma: role of monocytes].
Topics: Adolescent; Adult; Catalase; Cells, Cultured; Child; Child, Preschool; Hemolytic Plaque Technique; H | 1987 |
Decreased expression of class II major histocompatibility antigens on monocytes from patients with Hodgkin's disease.
Topics: Adult; Concanavalin A; Female; Histocompatibility Antigens Class II; HLA-DR Antigens; Hodgkin Diseas | 1986 |
Antipyretic effect of indomethacin in malignant lymphoma.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Female; Hodgkin Disease; Hum | 1986 |
Impaired proliferative response and low interleukin-2 production in patients with lymphoma.
Topics: Adolescent; Adult; Aged; Female; Hodgkin Disease; Humans; Immune Sera; Immune Tolerance; Immunity, C | 1987 |
Nephrotic syndrome preceding Hodgkin's disease by 42 months.
Topics: Cyclophosphamide; Drug Therapy, Combination; Hodgkin Disease; Humans; Indomethacin; Male; Middle Age | 1986 |
Defect in lectin-induced interleukin 2 (IL-2) production by peripheral blood lymphocytes of patients with Hodgkin's disease.
Topics: Adolescent; Adult; Cells, Cultured; Hodgkin Disease; Humans; Indomethacin; Interleukin-1; Interleuki | 1985 |
Normalization of monocyte candidacidal deficiency by cyclooxygenase inhibitors in Hodgkin's disease.
Topics: Adolescent; Adult; Aspirin; Candida; Cells, Cultured; Child; Child, Preschool; Cyclooxygenase Inhibi | 1985 |
Impaired interleukin regulation of the phytohemagglutinin response in Hodgkin's disease.
Topics: Adult; Antibodies, Monoclonal; Catalase; Dinoprostone; Female; Histocompatibility Antigens Class II; | 1985 |
[Abnormal regulation in the production of IL2 in Hodgkin's disease].
Topics: Hodgkin Disease; Humans; In Vitro Techniques; Indomethacin; Interleukin-2; Lymphocytes | 1985 |
The effect of indomethacin treatment on lymphocyte PHA reactivity in healthy controls and patients with lymphoma and sarcoidosis.
Topics: Adolescent; Adult; Cells, Cultured; Female; Hodgkin Disease; Humans; Indomethacin; Lymphocyte Activa | 1985 |
Erythema nodosum heralding recurrent Hodgkin's disease.
Topics: Adolescent; Adult; Erythema Nodosum; Hodgkin Disease; Humans; Indomethacin; Male; Neoplasm Recurrenc | 1985 |
Symptomatic control of fever in lymphoma and leukemia.
Topics: Adolescent; Adult; Aged; Aminopyrine; Analgesics; Aspirin; Female; Fever; Hodgkin Disease; Humans; I | 1969 |
Use of Indomethacin as an anti-pyretic agent in malignant reticulosis.
Topics: Adolescent; Adult; Child; Evaluation Studies as Topic; Female; Fever; Hodgkin Disease; Humans; Indom | 1972 |
Antipyretic effect of indomethacin in patients with malignancy.
Topics: Anti-Bacterial Agents; Body Temperature; Female; Fever; Hodgkin Disease; Humans; Indomethacin; Leuke | 1968 |
[Use of indomethacin in internal and hematologic practice].
Topics: Hodgkin Disease; Humans; Indomethacin; Joint Diseases; Leukemia; Lymphoma; Lymphoma, Large B-Cell, D | 1970 |
[Indomethacin in hemoblastosis].
Topics: Hodgkin Disease; Humans; Indomethacin; Joint Diseases; Leukemia; Lymphoma; Lymphoma, Large B-Cell, D | 1971 |
[Indomethacin and hematopoiesis. Antipyretic and antiphlogistic effects in hemoblastoses and various uncommon diseases].
Topics: Arthritis, Infectious; Arthritis, Rheumatoid; Dermatomyositis; Female; Hematologic Diseases; Hematop | 1968 |
[Clinical research on the antipyretic effects of indomethacin in systemic hemopathies].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anemia, Aplastic; Antibiotics, Antineoplastic; Ant | 1970 |
[Antiphlogistic and analgetic effect of indomethazine in patients with inflammatory joint diseases, carcinoma, lymphogranulomatosis and chronic myelosis].
Topics: Adult; Aged; Arthritis; Female; Gout; Hodgkin Disease; Humans; Indomethacin; Leukemia, Myeloid; Male | 1971 |
[Clinical observations on the treatment of rheumatic diseases and other morbid states with indomethacin].
Topics: Anemia, Hemolytic, Autoimmune; Arthritis, Rheumatoid; Asthma; Crohn Disease; Dexamethasone; Hodgkin | 1966 |
[Clinical experience with indomethacin].
Topics: Arthritis, Rheumatoid; Hodgkin Disease; Humans; Indomethacin; Joint Diseases; Leukemia, Myeloid; Lup | 1968 |
[Antipyretic activity of indomethacin in histiocytic sarcomatosis of a systemic type].
Topics: Adolescent; Adult; Aged; Female; Histiocytes; Hodgkin Disease; Humans; Indomethacin; Leukemia; Male; | 1967 |
Control of fever in Hodgkin's disease by indomethacin.
Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Aspirin; Female; Fever | 1965 |
[On the antipyretic action of indomethacin in Hodgkin's lymphogranuloma and in neoplasms].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Fever; Hodgkin Disease; Human | 1966 |