Page last updated: 2024-10-29

indomethacin and Hepatitis, Animal

indomethacin has been researched along with Hepatitis, Animal in 4 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Hepatitis, Animal: INFLAMMATION of the LIVER in non-human animals.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with indomethacin (IMC) did not abrogate significantly the protective effect of IL-1."1.29The effect of interleukin 1 alpha on acetaminophen-induced hepatotoxicity. ( Bilić, A; Bukovec, Z; Culo, F; Renić, M; Sabolović, D; Zupanović, Z, 1993)
"Treatment with indomethacin, hydrocortisone, dexamethasone, promethazine, metiazinic acid and (+)-catechin ameliorated the liver damage."1.26Protection of mice against endotoxin-induced liver damage by anti-inflammatory drugs. ( Allison, AC; Ferluga, J; Kaplun, A, 1979)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Renić, M1
Culo, F1
Bilić, A1
Bukovec, Z1
Sabolović, D1
Zupanović, Z1
Ferluga, J1
Kaplun, A1
Allison, AC1
Ogawa, M1
Mori, T1
Mori, Y1
Ueda, S1
Yoshida, H1
Kato, I1
Iesato, K1
Wakashin, Y1
Wakashin, M1
Okuda, K1
Wendel, A1
Tiegs, G1

Other Studies

4 other studies available for indomethacin and Hepatitis, Animal

ArticleYear
The effect of interleukin 1 alpha on acetaminophen-induced hepatotoxicity.
    Cytokine, 1993, Volume: 5, Issue:3

    Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Dinoprostone; Dose-Respon

1993
Protection of mice against endotoxin-induced liver damage by anti-inflammatory drugs.
    Agents and actions, 1979, Volume: 9, Issue:5-6

    Topics: Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Blood Glucose; Endotoxins; Female; H

1979
Inhibitory effects of prostaglandin E1 on T-cell mediated cytotoxicity against isolated mouse liver cells.
    Gastroenterology, 1988, Volume: 94, Issue:4

    Topics: Alprostadil; Animals; Cells, Cultured; Cytotoxicity, Immunologic; Hepatitis, Animal; Indomethacin; L

1988
A novel biologically active seleno-organic compound--VI. Protection by ebselen (PZ 51) against galactosamine/endotoxin-induced hepatitis in mice.
    Biochemical pharmacology, 1986, Jul-01, Volume: 35, Issue:13

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Azoles; Chemical and Drug Induced Liver

1986