indomethacin has been researched along with Hepatic Encephalopathy in 6 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with hepatic encephalopathy and Reye's syndrome have elevated levels of plasma octanoate." | 5.28 | On octanoic acid-induced hyperventilation--implications for hepatic encephalopathy and Reye's syndrome. ( Jumbasova, S; Kostadinova, I; Krustev, A; Mitkov, D; Toreva, D, 1989) |
| "Patients with hepatic encephalopathy and Reye's syndrome have elevated levels of plasma octanoate." | 1.28 | On octanoic acid-induced hyperventilation--implications for hepatic encephalopathy and Reye's syndrome. ( Jumbasova, S; Kostadinova, I; Krustev, A; Mitkov, D; Toreva, D, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brück, J | 1 |
| Görg, B | 1 |
| Bidmon, HJ | 1 |
| Zemtsova, I | 1 |
| Qvartskhava, N | 1 |
| Keitel, V | 1 |
| Kircheis, G | 2 |
| Häussinger, D | 2 |
| Ahboucha, S | 1 |
| Jiang, W | 1 |
| Chatauret, N | 1 |
| Mamer, O | 1 |
| Baker, GB | 1 |
| Butterworth, RF | 1 |
| de Kraker-Sangster, M | 1 |
| Bronkhorst, FB | 1 |
| Brandt, KH | 1 |
| Boersma, JW | 1 |
| Kristev, A | 1 |
| Mitkov, D | 2 |
| Lukanov, Y | 1 |
| Chapkynov, P | 1 |
| Toreva, D | 1 |
| Krustev, A | 1 |
| Kostadinova, I | 1 |
| Jumbasova, S | 1 |
1 review available for indomethacin and Hepatic Encephalopathy
| Article | Year |
|---|---|
[Hepatic encephalopathy].
Topics: Amino Acids, Branched-Chain; Ammonia; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Automobil | 2012 |
5 other studies available for indomethacin and Hepatic Encephalopathy
| Article | Year |
|---|---|
Locomotor impairment and cerebrocortical oxidative stress in portal vein ligated rats in vivo.
Topics: Animals; Cerebral Cortex; Cytokines; Hepatic Encephalopathy; Hyperammonemia; Indomethacin; Ligation; | 2011 |
Indomethacin improves locomotor deficit and reduces brain concentrations of neuroinhibitory steroids in rats following portacaval anastomosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Brain; Brain Chemistry; Desoxycorticostero | 2008 |
[Massive liver cell necrosis following administration of indomethacin in combination with aminophenzone].
Topics: Adult; Aminopyrine; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Hepatic Encep | 1981 |
The effect of octanoic fatty acid on the cardiovascular system of the guinea pig.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Caprylates; Cardiac Output; Cardiovascular Disease | 1989 |
On octanoic acid-induced hyperventilation--implications for hepatic encephalopathy and Reye's syndrome.
Topics: Alkalosis, Respiratory; Animals; Blood Pressure; Caprylates; Electroencephalography; Hepatic Encepha | 1989 |