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indomethacin and Hemolysis

indomethacin has been researched along with Hemolysis in 38 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
" Oral bioavailability and anti-inflammation effect of IMC delivery systems established by CMSN and Amino-CMSN were enhanced compared with IMC, which was attributed to the primary cause of the improvement of IMC dissolution, and Amino-CMSN exhibited better biological effect."1.48Superiority of amino-modified chiral mesoporous silica nanoparticles in delivering indometacin. ( Guo, Y; Li, H; Li, J; Li, S; Shang, L, 2018)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199027 (71.05)18.7374
1990's4 (10.53)18.2507
2000's2 (5.26)29.6817
2010's5 (13.16)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Galet, V1
Bernier, JL1
Hénichart, JP1
Lesieur, D1
Abadie, C1
Rochette, L1
Lindenbaum, A1
Chalas, J1
Renaud de la Faverie, JF1
Pfeiffer, B1
Alonso-Castro, AJ1
Zapata-Morales, JR1
Hernández-Munive, A1
Campos-Xolalpa, N1
Pérez-Gutiérrez, S1
Pérez-González, C1
Li, J1
Guo, Y1
Li, H1
Shang, L1
Li, S1
Wersig, T1
Krombholz, R1
Janich, C1
Meister, A1
Kressler, J1
Mäder, K1
Aghajanzadeh, M1
Ghannad, F1
Zamani, M1
Andalib, S1
Danafar, H1
Navath, RS1
Menjoge, AR1
Wang, B1
Romero, R1
Kannan, S1
Kannan, RM1
Łania-Pietrzak, B1
Michalak, K1
Hendrich, AB1
Mosiadz, D1
Grynkiewicz, G1
Motohashi, N1
Shirataki, Y1
Marceau, F1
Hugli, TE1
Minta, JO1
Urowitz, MB1
Smythe, HA1
Isenman, DE1
Gullikson, GW1
Sender, M1
Bass, P1
Görög, P1
Kovács, IB1
Raghava, GP1
Goel, A1
Singh, AM1
Varshney, GC1
Barrios, JM1
Lichtenberger, LM1
Fredholm, BB1
Hedqvist, P1
Galettis, P1
Norton, RS1
Kato, H1
Yoneta, T1
Yoshida, A1
Ozeki, M1
Tagashira, E1
Evans, J1
Wang, YD1
Shaw, KP1
Vernon, LP1
Villar, A1
Gascó, MA1
Alcaraz, MJ1
Stelzner, A1
Schleef, H1
Villa, ML1
Rappocciolo, G1
Piazza, P1
Roubal, Z1
Grimová, J1
Nĕmecek, O1
Cepelák, V1
Mizushima, Y2
Sakai, S2
Saarnivaara, L1
Gieldanowski, J1
Szary, A1
Kowalczyk-Bronisz, SH1
Ignarro, LJ1
Slywka, J1
Tsurumi, K3
Nozaki, M2
Hayashi, M3
Yamaguchi, A1
Hiramatsu, Y2
Di Perri, T1
Auteri, A1
Fujimura, H1
Abe, A1
Nakano, K1
Shibuya, T1
Sofia, RD1
Delgado, CJ1
Douglas, JF1
Sheppard, H1
Tsien, WH1
Burghardt, C1
Kalbhen, DA1
Gelderblom, P1
Domenjoz, R1
Yamaura, M1
Nakanishi, M1
Imamura, H1
Ikegami, K1
Goto, K1
Artini, D1
Logemann, W1
Melloni, P1
Vita, G1
Buttinoni, A1
Tommasini, R1
Brown, JH2
Taylor, JL1
Waters, IW1
Mackey, HK1
Glenn, EM1
Bowman, BJ1

Other Studies

38 other studies available for indomethacin and Hemolysis

ArticleYear
Benzoselenazolinone derivatives designed to be glutathione peroxidase mimetics feature inhibition of cyclooxygenase/5-lipoxygenase pathways and anti-inflammatory activity.
    Journal of medicinal chemistry, 1994, Sep-02, Volume: 37, Issue:18

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Azoles; Cyclooxygenase Inhibitors; G

1994
Synthesis, antinociceptive and anti-inflammatory effects of porphyrins.
    Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10

    Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Exper

2015
Superiority of amino-modified chiral mesoporous silica nanoparticles in delivering indometacin.
    Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:5

    Topics: Adsorption; Animals; Anti-Inflammatory Agents; Cattle; Drug Carriers; Drug Liberation; Hemolysis; In

2018
Indomethacin functionalised poly(glycerol adipate) nanospheres as promising candidates for modified drug release.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Oct-15, Volume: 123

    Topics: A549 Cells; Aluminum Oxide; Animals; Cell Survival; Chemistry, Pharmaceutical; Cyclooxygenase Inhibi

2018
Anti-inflammatory effect of rosuvastatin using diblock amphiphilic copolymer: Synthesis, characterization, in vitro and in vivo study.
    Journal of biomaterials applications, 2019, Volume: 34, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Drug Liberation; HEK293 Cells; Hemolysis; Humans; Indomethacin; L

2019
Amino acid-functionalized dendrimers with heterobifunctional chemoselective peripheral groups for drug delivery applications.
    Biomacromolecules, 2010, Jun-14, Volume: 11, Issue:6

    Topics: Amino Acids; Animals; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Chromatography, High

2010
Modulation of MRP1 protein transport by plant, and synthetically modified flavonoids.
    Life sciences, 2005, Aug-26, Volume: 77, Issue:15

    Topics: Dose-Response Relationship, Drug; Erythrocytes; Flavonoids; Fluoresceins; Genistein; Hemolysis; Huma

2005
Effect of C3a and C5a anaphylatoxins on guinea-pig isolated blood vessels.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:3

    Topics: Anaphylatoxins; Animals; Aspirin; Blood Vessels; Chromones; Complement C3; Complement C3a; Complemen

1984
Effect on the human complement system of the major non-steroidal anti-inflammatory drugs: aspirin, indomethacin, phenylbutazone, oxyphenbutazone and sulindac.
    Clinical and experimental immunology, 1983, Volume: 53, Issue:3

    Topics: Anti-Inflammatory Agents; Aspirin; Centrifugation, Density Gradient; Chromatography, Gel; Complement

1983
Laxative-like effects of nonsteroidal anti-inflammatory drugs on intestinal fluid movement and membrane integrity.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 220, Issue:2

    Topics: Alprostadil; Animals; Anti-Inflammatory Agents; Aspirin; Body Fluids; Cathartics; Cricetinae; Diarrh

1982
Impaired red cell deformability in established adjuvant arthritic disease in rats.
    Agents and actions, 1980, Volume: 10, Issue:5

    Topics: Animals; Arthritis; Arthritis, Experimental; Aspirin; Erythrocytes; Hemolysis; Hot Temperature; Hydr

1980
A simple microassay for computing the hemolytic potency of drugs.
    BioTechniques, 1994, Volume: 17, Issue:6

    Topics: Animals; Electronic Data Processing; Erythrocytes; Flufenamic Acid; Hemolysis; Ibuprofen; Indomethac

1994
Role of biliary phosphatidylcholine in bile acid protection and NSAID injury of the ileal mucosa in rats.
    Gastroenterology, 2000, Volume: 118, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile Acids and Salts; Erythrocytes; Hemolysis; Ile

2000
Indomethacin and the role of prostaglandins in adipose tissue.
    Biochemical pharmacology, 1975, Jan-01, Volume: 24, Issue:1

    Topics: Adipose Tissue; Animals; Blood Glucose; Carbon Radioisotopes; Cell Membrane; Cyclic AMP; Dogs; Elect

1975
Biochemical and pharmacological studies of the mechanism of action of tenebrosin-C, a cardiac stimulatory and haemolytic protein from the sea anemone, Actinia tenebrosa.
    Toxicon : official journal of the International Society on Toxinology, 1990, Volume: 28, Issue:6

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cardiotonic Agents; Cnidaria; Guinea Pigs; He

1990
[Interaction of CN-100, a novel non-steroidal anti-inflammatory drug, on biopolymers].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1990, Volume: 96, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Benzothiepins; Dose-Response Relationship, Dru

1990
Cellular responses to Pyrularia thionin are mediated by Ca2+ influx and phospholipase A2 activation and are inhibited by thionin tyrosine iodination.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:15

    Topics: Animals; Antimicrobial Cationic Peptides; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Line; C

1989
Some aspects of the inhibitory activity of hypolaetin-8-glucoside in acute inflammation.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Female; Flavonoids; Glucur

1987
[The influence of carrageenan, colchicine, 2,4-dinitrophenol, ethanol, galactose, indomethacin and liquoid on hemolytic complement activity (CH50E)].
    Allergie und Immunologie, 1986, Volume: 32, Issue:2

    Topics: 2,4-Dinitrophenol; Animals; Benzenesulfonates; Carrageenan; Colchicine; Complement Inactivator Prote

1986
Primary in vitro antibody response in humans: role of adherent cells in the development of haemolytic colonies.
    Immunology, 1986, Volume: 58, Issue:4

    Topics: Adult; Antibody Formation; Arachidonic Acids; Catalase; Cell Adhesion; Cells, Cultured; Dinoprostone

1986
Effects of nonsteroid anti-inflammatory agents and some dicoumarol derivatives on platelet aggregation, fibrinolysis and stabilization of cell membrane in vitro.
    Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 53

    Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Cell Membrane; Chloroquine; Coumarins; Depressio

1972
Stabilization of erythrocyte membrane by non-steroianti-inflammatory drugs.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Cell Membrane; Dogs; Erythrocytes; Flufenamic Acid; Hemolysis; Ho

1969
Influence of some drugs on the accumulation of morphine in rabbit red cells in vitro.
    Annales medicinae experimentalis et biologiae Fenniae, 1969, Volume: 47, Issue:2

    Topics: Analgesia; Animals; Cyproheptadine; Diphenhydramine; Dopamine; Drug Synergism; Erythrocytes; Hemolys

1969
A method for determining stabilization of erythrocytic membranes.
    Archivum immunologiae et therapiae experimentalis, 1974, Volume: 22, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Cell Membrane; Erythrocytes; Hemolysis; Hydrocortisone; Indometha

1974
Changes in liver lysosome fragility, erythrocyte membrane stability, and local and systemic lysosomal enzyme levels in adjuvant-induced polyarthritis.
    Biochemical pharmacology, 1972, Mar-15, Volume: 21, Issue:6

    Topics: Acid Phosphatase; Adjuvants, Immunologic; Animals; Arthritis; Cell Membrane; Erythrocytes; Foot; Glu

1972
[Pharmacological studies on niflumic acid, with special reference to the comparison with fenametes. 1. Anti-inflammatory and analgesic actions].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:6

    Topics: Analgesics; Aniline Compounds; Animals; Anti-Inflammatory Agents; Arthritis; Capillary Permeability;

1972
[Anti-complement activity in vitro and in vivo of some non-steroid anti-inflammatory drugs].
    Bollettino della Societa italiana di biologia sperimentale, 1973, Feb-28, Volume: 49, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Complement Inactivator Proteins; Flufenamic Acid; Hemoly

1973
[Pharmacological studies of N-benzoyl-N'-phenyl-2,6-diaminobenzoic acid (F1). 3. Interaction with proteins].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:6

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoates; Benzyl Compounds; Blo

1973
[Anti-inflammatory action of N-(2,6-dichlorophenyl)-o-aminophenylacetic acid, its sodium salt, N-(2,6-dichlorophenyl)-anthranilic acid and its sodium salt. 1. On acute inflammation].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:2

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Capillary Permeability; Edema; Electrolytes; Eryth

1973
The effects of various naturally occurring cannabinoids on hypotonic-hyperthermic lysis of rat erythrocytes.
    European journal of pharmacology, 1974, Volume: 27, Issue:1

    Topics: Animals; Aspirin; Cannabis; Cell Membrane; Dose-Response Relationship, Drug; Dronabinol; Erythrocyte

1974
Effect of drugs on the hemolysis of rat erythrocytes.
    Biochemical pharmacology, 1969, Volume: 18, Issue:9

    Topics: Animals; Aspirin; Bile Acids and Salts; Chlordiazepoxide; Chloroquine; Chlorpromazine; Chlorprothixe

1969
Effects of antirheumatic drugs on human erythrocyte membranes.
    Pharmacology, 1970, Volume: 3, Issue:6

    Topics: Aminobenzoates; Analgesics; Antipyrine; Aspirin; Barbiturates; Benzoates; Cell Membrane; Erythrocyte

1970
Mode of stabilizing action of non-steroid anti-inflammatory drugs on erythrocyte membrane.
    Biochemical pharmacology, 1970, Volume: 19, Issue:1

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Blood Coagulation; Cell Membrane; Dogs; Ery

1970
Pharmacological investigations of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Acid Phosphatase; Analgesics; Animals; Anti-Inflammatory Agents; Antibody Formation; Aspirin; Blood

1970
[Analgesic and antiphlogistic action of amide and amine compounds. 1].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Amides; Amines; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Depression, Chemical; Ed

1970
Effect of pH on erythrocyte stabilization by anti-inflammatory drugs.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 136, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Dogs; Erythrocytes; Goats; Guinea Pigs; Hemolysis; Horses; Humans

1971
Further studies on the erythrocyte anti-inflammatory assay.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 128, Issue:2

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Aspirin; Dimethyl Sulfoxide; Erythrocytes; Estrog

1968
In vitro effects of non-steroidal anti-inflammatory drugs (NAIFD).
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 130, Issue:4

    Topics: Acid Phosphatase; Animals; Anti-Inflammatory Agents; Biological Assay; Blood Platelets; Calcium; Ery

1969