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indomethacin and Hematologic Diseases

indomethacin has been researched along with Hematologic Diseases in 8 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Hematologic Diseases: Disorders of the blood and blood forming tissues.

Research Excerpts

ExcerptRelevanceReference
" Hydroquinone (HQ), a toxic bone marrow (BM) metabolite of BZ, causes time- and concentration-dependent inhibition of processing of the 34-Kd pre-interleukin-1 alpha (IL-1 alpha) to the 17-Kd mature cytokine in murine P388D1 macrophages and BM stromal macrophages, as measured by Western immunoblots of cell lysate proteins using a polyclonal rabbit antimurine IL-1 alpha antibody."1.28Role for interleukin-1 (IL-1) in benzene-induced hematotoxicity: inhibition of conversion of pre-IL-1 alpha to mature cytokine in murine macrophages by hydroquinone and prevention of benzene-induced hematotoxicity in mice by IL-1 alpha. ( Kalf, GF; Renz, JF, 1991)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takamura, S1
Teraki, Y1
MoszczyƄski, P1
Renz, JF1
Kalf, GF1
Schlegel, SI1
Paulus, HE1
Cuthbert, MF1
Treske, U1
Marcolongo, R1
Bianco, G1
Di Paolo, N1
Bravi, A1
Jaros, Z1

Reviews

2 reviews available for indomethacin and Hematologic Diseases

ArticleYear
Eosinophilic pustular folliculitis associated with hematological disorders: A report of two cases and review of Japanese literature.
    The Journal of dermatology, 2016, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; An

2016
Non-steroidal and analgesic therapy in the elderly.
    Clinics in rheumatic diseases, 1986, Volume: 12, Issue:1

    Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Cen

1986

Other Studies

6 other studies available for indomethacin and Hematologic Diseases

ArticleYear
[Letter: Effect of Metindol on the activity of alkaline phosphatase in neutrophil granulocytes].
    Przeglad lekarski, 1976, Volume: 33, Issue:4

    Topics: Adult; Alkaline Phosphatase; Female; Hematologic Diseases; Humans; Indomethacin; Male; Middle Aged;

1976
Role for interleukin-1 (IL-1) in benzene-induced hematotoxicity: inhibition of conversion of pre-IL-1 alpha to mature cytokine in murine macrophages by hydroquinone and prevention of benzene-induced hematotoxicity in mice by IL-1 alpha.
    Blood, 1991, Aug-15, Volume: 78, Issue:4

    Topics: Animals; Benzene; Blotting, Western; Bone Marrow Cells; Cells, Cultured; DNA; Hematologic Diseases;

1991
Adverse reactions to non-steroidal antirheumatic drugs.
    Current medical research and opinion, 1974, Volume: 2, Issue:9

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzophenones; Chemical and Drug Induced Liv

1974
[Indomethacin and hematopoiesis. Antipyretic and antiphlogistic effects in hemoblastoses and various uncommon diseases].
    Medizinische Klinik, 1968, Mar-01, Volume: 63, Issue:9

    Topics: Arthritis, Infectious; Arthritis, Rheumatoid; Dermatomyositis; Female; Hematologic Diseases; Hematop

1968
[Clinical research on the antipyretic effects of indomethacin in systemic hemopathies].
    Minerva medica, 1970, Oct-13, Volume: 61, Issue:82

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anemia, Aplastic; Antibiotics, Antineoplastic; Ant

1970
[Influence of drugs used in rheumatology on the blood].
    Vnitrni lekarstvi, 1971, Volume: 17, Issue:6

    Topics: Analgesics; Anti-Inflammatory Agents; Bone Marrow Diseases; Chloroquine; Corticosterone; Gold; Hemat

1971