indomethacin has been researched along with Hematologic Diseases in 8 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Hematologic Diseases: Disorders of the blood and blood forming tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hydroquinone (HQ), a toxic bone marrow (BM) metabolite of BZ, causes time- and concentration-dependent inhibition of processing of the 34-Kd pre-interleukin-1 alpha (IL-1 alpha) to the 17-Kd mature cytokine in murine P388D1 macrophages and BM stromal macrophages, as measured by Western immunoblots of cell lysate proteins using a polyclonal rabbit antimurine IL-1 alpha antibody." | 1.28 | Role for interleukin-1 (IL-1) in benzene-induced hematotoxicity: inhibition of conversion of pre-IL-1 alpha to mature cytokine in murine macrophages by hydroquinone and prevention of benzene-induced hematotoxicity in mice by IL-1 alpha. ( Kalf, GF; Renz, JF, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takamura, S | 1 |
| Teraki, Y | 1 |
| Moszczyński, P | 1 |
| Renz, JF | 1 |
| Kalf, GF | 1 |
| Schlegel, SI | 1 |
| Paulus, HE | 1 |
| Cuthbert, MF | 1 |
| Treske, U | 1 |
| Marcolongo, R | 1 |
| Bianco, G | 1 |
| Di Paolo, N | 1 |
| Bravi, A | 1 |
| Jaros, Z | 1 |
2 reviews available for indomethacin and Hematologic Diseases
| Article | Year |
|---|---|
Eosinophilic pustular folliculitis associated with hematological disorders: A report of two cases and review of Japanese literature.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; An | 2016 |
Non-steroidal and analgesic therapy in the elderly.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Cen | 1986 |
6 other studies available for indomethacin and Hematologic Diseases
| Article | Year |
|---|---|
[Letter: Effect of Metindol on the activity of alkaline phosphatase in neutrophil granulocytes].
Topics: Adult; Alkaline Phosphatase; Female; Hematologic Diseases; Humans; Indomethacin; Male; Middle Aged; | 1976 |
Role for interleukin-1 (IL-1) in benzene-induced hematotoxicity: inhibition of conversion of pre-IL-1 alpha to mature cytokine in murine macrophages by hydroquinone and prevention of benzene-induced hematotoxicity in mice by IL-1 alpha.
Topics: Animals; Benzene; Blotting, Western; Bone Marrow Cells; Cells, Cultured; DNA; Hematologic Diseases; | 1991 |
Adverse reactions to non-steroidal antirheumatic drugs.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzophenones; Chemical and Drug Induced Liv | 1974 |
[Indomethacin and hematopoiesis. Antipyretic and antiphlogistic effects in hemoblastoses and various uncommon diseases].
Topics: Arthritis, Infectious; Arthritis, Rheumatoid; Dermatomyositis; Female; Hematologic Diseases; Hematop | 1968 |
[Clinical research on the antipyretic effects of indomethacin in systemic hemopathies].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anemia, Aplastic; Antibiotics, Antineoplastic; Ant | 1970 |
[Influence of drugs used in rheumatology on the blood].
Topics: Analgesics; Anti-Inflammatory Agents; Bone Marrow Diseases; Chloroquine; Corticosterone; Gold; Hemat | 1971 |