Page last updated: 2024-10-29

indomethacin and Heart Failure

indomethacin has been researched along with Heart Failure in 62 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"The acute adverse effects of indomethacin on central and peripheral haemodynamic and renal function suggest that prostaglandins have a significant role in the regulation of peripheral blood flow and renal function in patients with stable chronic heart failure."9.08Peripheral haemodynamic effects of inhibition of prostaglandin synthesis in congestive heart failure and interactions with captopril. ( Davies, MK; Doran, J; Lote, CJ; Townend, JN, 1995)
"The interaction between renal prostaglandins and atrial natriuretic factor (ANF) for the regulation of renal hemodynamic and excretory function was examined in conscious dogs with arteriovenous fistula and chronic compensated high-output heart failure (n = 6)."7.69Indomethacin attenuates the renal actions of atrial natriuretic factor in dogs with chronic heart failure. ( Freeman, RH; Habibullah, AA; Simmons, JC; Villarreal, D, 1997)
"A case of severe fetal congestive heart failure due to occlusion of the ductus arteriosus in a mother treated with indomethacin for polyhydramnios and premature contractions is described."7.69In utero congestive heart failure due to maternal indomethacin treatment for polyhydramnios and premature labour in a fetus with antenatal closure of the foramen ovale. ( Achiron, R; Berant, M; Hegesh, J; Kidron, D; Lipitz, S; Rotstein, Z, 1996)
"We studied the effects of inhaled furosemide (40 mg) on bronchial responsiveness to acetylcholine (ACh) in patients with chronic congestive heart failure who had been premedicated with indomethacin (75 mg/day) for five days."7.69[Effects of inhaled furosemide after indomethacin premedication on bronchial hyperresponsiveness in patients with chronic congestive heart failure]. ( Ishizaki, T; Kanamori, K; Mifune, J; Miyabo, S; Nakai, T; Saitoh, Y; Sakai, T; Sasaki, F, 1994)
"The aims of this study were to investigate the influence of heart failure and dietary sodium content on the natriuretic effect of furosemide."7.67Influence of heart failure and sodium content in the diet on the natriuretic response to furosemide in hamsters. ( du Souich, P; Gutkowska, J; Lambert, C; Larose, P; Ong, H, 1985)
"The effects of captopril on the forearm hemodynamics in patients with severe congestive heart failure were studied, using strain-gauge plethysmography."7.67Effects of captopril on peripheral hemodynamics in severe congestive heart failure. ( Kawamura, K; Kubo, S; Kubota, J; Nishimura, H; Ueyama, M, 1987)
"In 14 patients with severe congestive heart failure, the effects of captopril on the forearm circulation were evaluated with strain gauge plethysmography."7.67Peripheral hemodynamic effects of captopril in patients with congestive heart failure. ( Kawamura, K; Kubo, S; Kubota, J; Nishimura, H; Ueyama, M, 1989)
" In series 1 during acute cardiac failure, indomethacin administration produced striking reductions in RHF but failed to alter the high level of plasma renin activity (PRA)."7.66Effects of indomethacin in conscious dogs with experimental high-output heart failure. ( Davis, JO; Dietz, JR; Echtenkamp, SF; Freeman, RH; Villarreal, D, 1983)
"Simultaneous administration of indomethacin and Moduretic (Merck Sharp & Dohme, USA, 5 mg of amiloride HCl, 50 mg hydrochlorothiazide) to a 78-yr-old patient resulted in severe hyperkalemia twice."7.66Indomethacin- and Moduretic--induced hyperkalemia. ( Mor, R; Pitlik, S; Rosenfeld, JB, 1983)
" Clentiazem dose-response curves for both coronary dilation and negative inotropic effects were determined under control conditions and in the presence of the nitric oxide (NO) synthase inhibitor, NG-nitro-L-arginine (L-NAME, 30 microM), and the cyclooxygenase inhibitor, indomethacin (10 microM)."5.30Coronary and cardiac sensitivity to the vasoselective benzothiazepine-like calcium antagonist, clentiazem, in experimental heart failure. ( Blaise, G; Dumont, L; Jasmin, G; Tanguay, M, 1997)
"Heart failure was not associated with increased cardiac sensitivity to diltiazem but rather with altered coronary sensitivity."5.29Impaired coronary sensitivity to diltiazem in experimental heart failure: involvement of the cyclooxygenase but not the nitric oxide-synthase pathway. ( Blaise, G; Dumont, L; Jasmin, G; Tanguay, M, 1996)
"Twenty-five patients with congestive heart failure and an ejection fraction less than 40% were evaluated."5.28Renal response to indomethacin in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. ( Fisher, ML; Gottlieb, SS; Krichten, CM; Robinson, S, 1992)
"The acute adverse effects of indomethacin on central and peripheral haemodynamic and renal function suggest that prostaglandins have a significant role in the regulation of peripheral blood flow and renal function in patients with stable chronic heart failure."5.08Peripheral haemodynamic effects of inhibition of prostaglandin synthesis in congestive heart failure and interactions with captopril. ( Davies, MK; Doran, J; Lote, CJ; Townend, JN, 1995)
"Ten patients in heart failure of various etiologies underwent a placebo-controlled study to determine the effect of indomethacin (150 mg daily by mouth) on urine volume, sodium chloride excretion, glomerular filtration rate, renal prostaglandins, as well as plasma renin and aldosterone concentrations before and after administration of 40 mg frusemide by mouth."5.06[Indomethacin and furosemide in patients with cardiac insufficiency. Kidney function, the renin-angiotensin system and renal prostaglandins]. ( Kahles, H; Riegger, AJ, 1987)
"Nonsteroidal antiinflammatory drugs (NSAIDs) as a class have been shown to increase the risk of congestive heart failure (CHF) compared with celecoxib."3.74Risk of congestive heart failure with nonsteroidal antiinflammatory drugs and selective Cyclooxygenase 2 inhibitors: a class effect? ( Hudson, M; Pilote, L; Rahme, E; Richard, H, 2007)
"The interaction between renal prostaglandins and atrial natriuretic factor (ANF) for the regulation of renal hemodynamic and excretory function was examined in conscious dogs with arteriovenous fistula and chronic compensated high-output heart failure (n = 6)."3.69Indomethacin attenuates the renal actions of atrial natriuretic factor in dogs with chronic heart failure. ( Freeman, RH; Habibullah, AA; Simmons, JC; Villarreal, D, 1997)
"A case of severe fetal congestive heart failure due to occlusion of the ductus arteriosus in a mother treated with indomethacin for polyhydramnios and premature contractions is described."3.69In utero congestive heart failure due to maternal indomethacin treatment for polyhydramnios and premature labour in a fetus with antenatal closure of the foramen ovale. ( Achiron, R; Berant, M; Hegesh, J; Kidron, D; Lipitz, S; Rotstein, Z, 1996)
"We studied the effects of inhaled furosemide (40 mg) on bronchial responsiveness to acetylcholine (ACh) in patients with chronic congestive heart failure who had been premedicated with indomethacin (75 mg/day) for five days."3.69[Effects of inhaled furosemide after indomethacin premedication on bronchial hyperresponsiveness in patients with chronic congestive heart failure]. ( Ishizaki, T; Kanamori, K; Mifune, J; Miyabo, S; Nakai, T; Saitoh, Y; Sakai, T; Sasaki, F, 1994)
"Digoxin was administered to an 18-day-old infant who showed evidence of cardiac failure."3.68Increase in serum digoxin concentrations after indomethacin therapy in a full-term neonate. ( Brookfield, EG; Haig, GM, 1992)
" Of 23 patients with severe heart failure challenged with indomethacin (an inhibitor of prostaglandin synthesis), the 9 with hyponatremia had significant decreases in the cardiac index (1."3.67Prostaglandins in severe congestive heart failure. Relation to activation of the renin--angiotensin system and hyponatremia. ( Dzau, VJ; Hollenberg, NK; Lilly, LS; Packer, M; Swartz, SL; Williams, GH, 1984)
"In 14 patients with severe congestive heart failure, the effects of captopril on the forearm circulation were evaluated with strain gauge plethysmography."3.67Peripheral hemodynamic effects of captopril in patients with congestive heart failure. ( Kawamura, K; Kubo, S; Kubota, J; Nishimura, H; Ueyama, M, 1989)
"The effects of captopril on the forearm hemodynamics in patients with severe congestive heart failure were studied, using strain-gauge plethysmography."3.67Effects of captopril on peripheral hemodynamics in severe congestive heart failure. ( Kawamura, K; Kubo, S; Kubota, J; Nishimura, H; Ueyama, M, 1987)
"The aims of this study were to investigate the influence of heart failure and dietary sodium content on the natriuretic effect of furosemide."3.67Influence of heart failure and sodium content in the diet on the natriuretic response to furosemide in hamsters. ( du Souich, P; Gutkowska, J; Lambert, C; Larose, P; Ong, H, 1985)
" In series 1 during acute cardiac failure, indomethacin administration produced striking reductions in RHF but failed to alter the high level of plasma renin activity (PRA)."3.66Effects of indomethacin in conscious dogs with experimental high-output heart failure. ( Davis, JO; Dietz, JR; Echtenkamp, SF; Freeman, RH; Villarreal, D, 1983)
"Simultaneous administration of indomethacin and Moduretic (Merck Sharp & Dohme, USA, 5 mg of amiloride HCl, 50 mg hydrochlorothiazide) to a 78-yr-old patient resulted in severe hyperkalemia twice."3.66Indomethacin- and Moduretic--induced hyperkalemia. ( Mor, R; Pitlik, S; Rosenfeld, JB, 1983)
"A patient with compensated congestive heart failure suffered acute deterioration of her renal function and cardiac status, requiring peritoneal dialysis, in association with indomethacin therapy."3.66Acute oliguric renal failure induced by indomethacin: possible mechanism. ( Venuto, RC; Walshe, JJ, 1979)
"Congestive heart failure is a clinical condition associated with alterations in the normal balance of neurohumoral agents and factors acting on the vascular wall."1.30Altered vascular function in early stages of heart failure in hamsters. ( Altieri, PI; Crespo, MJ; Escobales, N, 1997)
" Clentiazem dose-response curves for both coronary dilation and negative inotropic effects were determined under control conditions and in the presence of the nitric oxide (NO) synthase inhibitor, NG-nitro-L-arginine (L-NAME, 30 microM), and the cyclooxygenase inhibitor, indomethacin (10 microM)."1.30Coronary and cardiac sensitivity to the vasoselective benzothiazepine-like calcium antagonist, clentiazem, in experimental heart failure. ( Blaise, G; Dumont, L; Jasmin, G; Tanguay, M, 1997)
"Heart failure was not associated with increased cardiac sensitivity to diltiazem but rather with altered coronary sensitivity."1.29Impaired coronary sensitivity to diltiazem in experimental heart failure: involvement of the cyclooxygenase but not the nitric oxide-synthase pathway. ( Blaise, G; Dumont, L; Jasmin, G; Tanguay, M, 1996)
"Thirty-one patients with congestive heart failure (New York Heart Association functional class II-III) and five age-matched normal subjects were studied."1.29Impaired acetylcholine-mediated vasodilation in patients with congestive heart failure. Role of endothelium-derived vasodilating and vasoconstricting factors. ( Katz, SD; LeJemtel, TH; Schwarz, M; Yuen, J, 1993)
"Twenty-two patients with chronic treated heart failure (12 with secondary pulmonary hypertension, Group I; 10 with normal pulmonary artery pressure, Group II) and 8 control patients constituted the study groups."1.29Endothelium-dependent pulmonary artery responses in chronic heart failure: influence of pulmonary hypertension. ( Bagley, CW; Cycan, A; Fields, J; Mohanty, PK; Pandian, NG; Porter, TR; Taylor, DO, 1993)
"Twenty-five patients with congestive heart failure and an ejection fraction less than 40% were evaluated."1.28Renal response to indomethacin in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. ( Fisher, ML; Gottlieb, SS; Krichten, CM; Robinson, S, 1992)
"Usually congestive heart failure is considered to develop as a vicious cycle in which impaired cardiac output, increased peripheral resistance, decreased renal blood flow, increased renin release and further increased peripheral resistance and decreased cardiac output are important constituents."1.27Cardiovascular prostaglandins: some comments on their involvement in circulatory physiology and pathophysiology. ( Wennmalm, A, 1986)
"Our present policy for patent ductus arteriosus with respiratory distress syndrome in the premature baby is to initiate early treatment with indomethacin."1.26Management of patent ductus arteriosus in preterm babies. ( Alvarez, F; Burgueros, M; Gómez, R; Moreno, F; Quero, J; Sanchez, PA, 1980)
"9 pre-term babies with patent ductus arteriosus (P."1.26Plasma-prostaglandins in pre-term neonates before and after treatment for patient ductus arteriosus. ( Lucas, A; Mitchell, MD, 1978)
" This article attempts to critically review these studies under seven different sections: furosemide pharmacokinetics in normal volunteers, furosemide pharmacokinetics in patients with decreased renal function, furosemide pharmacokinetics in patients with congestive heart failure, furosemide metabolism and assay methods, furosemide bioavailability, dose-response relationships, and the role of inhibitors and mediators on furosemide effects."1.26Pharmacokinetics/pharmacodynamics of furosemide in man: a review. ( Benet, LZ, 1979)
"Patent ductus arteriosus was diagnosed in 239 neonates of low birth weight (less than 2500 g) referred to the Hospital for Sick Children in a 21/2-year period."1.26Patent ductus arteriosus in infants of low birth weight. ( Cook, DH; Izukawa, T; Olley, PM; Rowe, RD; Smith, DR; Swyer, PR, 1980)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199032 (51.61)18.7374
1990's18 (29.03)18.2507
2000's10 (16.13)29.6817
2010's2 (3.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tomlin, AM1
Woods, DJ1
Lloyd, HS1
Stewart, RAH1
Tilyard, MW1
Tongsong, T1
Luewan, S1
Srisupundit, K1
Jatavan, T1
Gschwend, S1
Henning, RH1
Pinto, YM1
de Zeeuw, D1
van Gilst, WH1
Buikema, H1
Pereira, RB1
Sartório, CL1
Vassallo, DV1
Stefanon, I1
Distefano, G1
Ovcharenko, E1
Abassi, Z3
Rubinstein, I2
Kaballa, A1
Hoffman, A2
Winaver, J2
Hudson, M1
Rahme, E1
Richard, H1
Pilote, L1
Middlekauff, HR1
Chiu, J1
Hamilton, MA1
Fonarow, GC1
Maclellan, WR1
Hage, A1
Moriguchi, J1
Patel, J1
Dzau, VJ1
Packer, M1
Lilly, LS1
Swartz, SL1
Hollenberg, NK1
Williams, GH1
Villarreal, D2
Davis, JO1
Freeman, RH2
Dietz, JR1
Echtenkamp, SF1
Gracián Gómez, M1
Rodríguez Caamaño, J1
Guía Torrent, JM1
Atik, E1
Moromizato, JH1
Zan, R1
Ajzenberg, M1
Esher, R1
Diniz, EM1
Souza, AT1
Martins, CO1
Bastos, JC1
Poe, TE1
Scott, RB1
Keith, JF1
Mor, R1
Pitlik, S1
Rosenfeld, JB1
Pillay, SP1
Hardie, IR1
Burnett, W1
Neal, WA1
Mullett, MD1
Prikryl, P1
Rysánek, K1
Továrek, J1
Carpi, A1
Del Basso, P1
Gómez, R1
Moreno, F1
Burgueros, M1
Sanchez, PA1
Quero, J1
Alvarez, F1
Schimmel, MS1
Inwood, RJ1
Eidelman, AI1
Eylath, U1
Yu, VY1
Smith, DR1
Cook, DH1
Izukawa, T1
Olley, PM1
Swyer, PR1
Rowe, RD1
Townend, JN1
Doran, J1
Lote, CJ1
Davies, MK1
Saitoh, Y1
Sasaki, F1
Sakai, T1
Ishizaki, T1
Nakai, T1
Miyabo, S1
Kanamori, K1
Mifune, J1
Porter, TR1
Taylor, DO1
Cycan, A1
Fields, J1
Bagley, CW1
Pandian, NG1
Mohanty, PK1
O'Murchu, B1
Miller, VM1
Perrella, MA1
Burnett, JC1
Katz, SD2
Schwarz, M1
Yuen, J1
LeJemtel, TH1
Achiron, R1
Lipitz, S1
Kidron, D1
Berant, M1
Hegesh, J1
Rotstein, Z1
Wang, W1
Zucker, IH1
Tanguay, M2
Jasmin, G2
Blaise, G2
Dumont, L2
Habibullah, AA1
Simmons, JC1
Lang, CC1
Chomsky, DB1
Butler, J1
Kapoor, S1
Wilson, JR1
Crespo, MJ1
Altieri, PI1
Escobales, N1
Horigome, H1
Malmsjö, M1
Bergdahl, A1
Zhao, XH1
Sun, XY1
Hedner, T1
Edvinsson, L1
Erlinge, D1
Niitsuma, T1
Saito, T1
Tamagawa, K1
Saitoh, S1
Mitsugi, M1
Sato, M1
Maehara, K1
Maruyama, Y1
Brodsky, S1
Gealekman, O1
Krum, H1
Goldfarb, M1
Rosen, S1
Shina, A1
Brezis, M1
Heyman, SN1
Mushiake, K1
Motoyoshi, F1
Kinoshita, Y1
Nakagawa, A1
Ito, M1
Lucas, A1
Mitchell, MD1
Ivey, HH1
Kattwinkel, J1
Park, TS1
Krovetz, LJ1
Kaplan, S1
Gaum, WE1
Benzing, G1
Meyer, RA1
Schwartz, DC1
Benet, LZ1
Walshe, JJ1
Venuto, RC1
Heymann, MA1
Hoffman, JI1
Bavoux, F1
Haig, GM1
Brookfield, EG1
Gottlieb, SS1
Robinson, S1
Krichten, CM1
Fisher, ML1
Momma, K1
Takao, A1
Riegger, GA1
Elsner, D1
Hildenbrand, J1
Koch, K1
Kromer, EP1
Nishimura, H2
Kubo, S2
Ueyama, M2
Kubota, J2
Kawamura, K2
George, BL1
Friedman, WF1
Kahles, H1
Riegger, AJ1
Van den Ouweland, FA1
Gribnau, FW1
Meyboom, RH1
Wennmalm, A1
Koopmans, PP1
Lambert, C1
Larose, P1
Ong, H1
Gutkowska, J1
du Souich, P1
Calabro, JJ1
Katz, RM1
Maltz, BA1
Phelps, P1

Reviews

6 reviews available for indomethacin and Heart Failure

ArticleYear
[The pharmacological manipulation of Botallo's duct in the duct-dependent congenital cardiopathies and in the preterm infants with respiratory distress. A review and personal findings].
    Minerva pediatrica, 2005, Volume: 57, Issue:1

    Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Agents; Cerebral Angiography; C

2005
[Recent advances and future perspectives in the medical treatment of cardiopathies in children].
    Revista espanola de cardiologia, 1984, Volume: 37 Suppl 1

    Topics: Child; Ductus Arteriosus, Patent; Heart Defects, Congenital; Heart Failure; Humans; Hypoxia; Indomet

1984
Therapeutic advances in pediatric cardiology.
    Pediatric clinics of North America, 1978, Volume: 25, Issue:4

    Topics: Adult; Animals; Child; Digitalis Glycosides; Dogs; Ductus Arteriosus; Ductus Arteriosus, Patent; Ech

1978
[Fetal toxicity of non-steroidal anti-inflammatory agents].
    Presse medicale (Paris, France : 1983), 1992, Nov-28, Volume: 21, Issue:40

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Fetal Diseases; Heart Failure; Humans; Indomethacin

1992
Pathophysiological and clinical aspects of the interaction between non-steroidal anti-inflammatory drugs (NSAID) and diuretics.
    The Netherlands journal of medicine, 1985, Volume: 28, Issue:11

    Topics: Anti-Inflammatory Agents; Diuretics; Drug Interactions; Drug Therapy, Combination; Heart Failure; Hu

1985
A critical reappraisal of juvenile rheumatoid arthritis.
    Clinical orthopaedics and related research, 1971, Volume: 74

    Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine

1971

Trials

4 trials available for indomethacin and Heart Failure

ArticleYear
Cyclooxygenase products sensitize muscle mechanoreceptors in humans with heart failure.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

    Topics: Adenosine; Adult; Aminophylline; Blood Pressure; Cyclooxygenase Inhibitors; Double-Blind Method; Fem

2008
Peripheral haemodynamic effects of inhibition of prostaglandin synthesis in congestive heart failure and interactions with captopril.
    British heart journal, 1995, Volume: 73, Issue:5

    Topics: Aged; Blood Pressure; Captopril; Cardiac Output; Dinoprostone; Double-Blind Method; Female; Glomerul

1995
Prostaglandin production contributes to exercise-induced vasodilation in heart failure.
    Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 83, Issue:6

    Topics: Cyclooxygenase Inhibitors; Exercise; Heart Failure; Hemodynamics; Humans; Indomethacin; Leg; Middle

1997
[Indomethacin and furosemide in patients with cardiac insufficiency. Kidney function, the renin-angiotensin system and renal prostaglandins].
    Deutsche medizinische Wochenschrift (1946), 1987, Nov-06, Volume: 112, Issue:45

    Topics: Clinical Trials as Topic; Drug Therapy, Combination; Furosemide; Heart Failure; Humans; Indomethacin

1987

Other Studies

52 other studies available for indomethacin and Heart Failure

ArticleYear
Understanding medicines with a propensity to increase the risk of heart failure: Combining existing knowledge with targeted population assessment.
    Pharmacoepidemiology and drug safety, 2018, Volume: 27, Issue:9

    Topics: Aged; Aged, 80 and over; Albuterol; Antifungal Agents; Case-Control Studies; Clozapine; Diltiazem; D

2018
Hemodynamic assessment of indomethacin-induced fetal heart failure in high-output state.
    Journal of clinical ultrasound : JCU, 2013, Volume: 41, Issue:7

    Topics: Adult; Female; Heart Failure; Hemangioma; Hemodynamics; Humans; Hydrops Fetalis; Indomethacin; Infan

2013
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.
    British journal of pharmacology, 2003, Volume: 139, Issue:7

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds

2003
Differences in tail vascular bed reactivity in rats with and without heart failure following myocardial infarction.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Heart Failure; Indomethacin; Male; Myocardial Infarction;

2005
Renal effects of human urotensin-II in rats with experimental congestive heart failure.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:5

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Glomerular Filtration Rate; Heart Failure; He

2006
Risk of congestive heart failure with nonsteroidal antiinflammatory drugs and selective Cyclooxygenase 2 inhibitors: a class effect?
    Arthritis and rheumatism, 2007, Apr-15, Volume: 57, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Celecoxib; C

2007
Prostaglandins in severe congestive heart failure. Relation to activation of the renin--angiotensin system and hyponatremia.
    The New England journal of medicine, 1984, Feb-09, Volume: 310, Issue:6

    Topics: Adult; Aged; Dinoprostone; Epoprostenol; Female; Heart Failure; Hemodynamics; Homeostasis; Humans; H

1984
Effects of indomethacin in conscious dogs with experimental high-output heart failure.
    The American journal of physiology, 1983, Volume: 245, Issue:6

    Topics: Animals; Blood Pressure; Dinoprostone; Disease Models, Animal; Dogs; Female; Heart; Heart Failure; H

1983
[Efficacy of indomethacin in the closure of patent ductus arteriosus in premature newborn infants with cardiac insufficiency. Analysis of 14 cases].
    Arquivos brasileiros de cardiologia, 1984, Volume: 43, Issue:3

    Topics: Birth Weight; Ductus Arteriosus, Patent; Electrocardiography; Heart Failure; Heart Murmurs; Humans;

1984
Interaction of indomethacin with furosemide.
    The Journal of family practice, 1983, Volume: 16, Issue:3

    Topics: Aged; Arthritis; Drug Interactions; Female; Furosemide; Gout; Heart Failure; Humans; Indomethacin; W

1983
Indomethacin- and Moduretic--induced hyperkalemia.
    Israel journal of medical sciences, 1983, Volume: 19, Issue:6

    Topics: Aged; Amiloride; Diabetes Complications; Diabetes Mellitus; Drug Combinations; Drug Interactions; Fe

1983
Emergency surgery for the complications of peptic ulcer in the elderly.
    The Australian and New Zealand journal of surgery, 1981, Volume: 51, Issue:6

    Topics: Aged; Emergencies; Heart Failure; Humans; Indomethacin; Lung Diseases, Obstructive; Peptic Ulcer; Sa

1981
Patent ductus arteriosus in premature infants: a review of current management.
    Pediatric cardiology, 1982, Volume: 3, Issue:1

    Topics: Ductus Arteriosus, Patent; Heart Failure; Humans; Indomethacin; Infant, Newborn; Infant, Premature,

1982
Psychosomatic stress and lipoperoxides of human platelet-rich plasma.
    Activitas nervosa superior, 1980, Volume: 22, Issue:4

    Topics: Aspirin; Female; Heart Failure; Humans; Indomethacin; Lipid Peroxides; Male; Middle Aged; Stress, Ps

1980
[Interaction between heart and lung functions in a heart-lung preparation: rheological aspects].
    Vestnik Akademii meditsinskikh nauk SSSR, 1980, Issue:1

    Topics: Animals; Guinea Pigs; Heart; Heart Failure; In Vitro Techniques; Indomethacin; Lung; Platelet Aggreg

1980
Management of patent ductus arteriosus in preterm babies.
    The Annals of thoracic surgery, 1980, Volume: 29, Issue:5

    Topics: Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Heart Failure; Humans; Indomethacin; Infant, N

1980
Toxic digitalis levels associated with indomethacin therapy in a neonate.
    Clinical pediatrics, 1980, Volume: 19, Issue:11

    Topics: Creatinine; Digoxin; Ductus Arteriosus, Patent; Heart Failure; Humans; Indomethacin; Infant, Newborn

1980
Patent ductus arteriosus in preterm infants.
    The Medical journal of Australia, 1980, Aug-23, Volume: 2, Issue:4

    Topics: Ductus Arteriosus, Patent; Heart Failure; Humans; Hyaline Membrane Disease; Indomethacin; Infant, Ne

1980
Patent ductus arteriosus in infants of low birth weight.
    Canadian Medical Association journal, 1980, Oct-18, Volume: 123, Issue:8

    Topics: Ductus Arteriosus, Patent; Female; Heart Failure; Humans; Indomethacin; Infant, Low Birth Weight; In

1980
[Effects of inhaled furosemide after indomethacin premedication on bronchial hyperresponsiveness in patients with chronic congestive heart failure].
    Nihon Kyobu Shikkan Gakkai zasshi, 1994, Volume: 32, Issue:5

    Topics: Administration, Inhalation; Aged; Aged, 80 and over; Bronchial Hyperreactivity; Chronic Disease; Fem

1994
Endothelium-dependent pulmonary artery responses in chronic heart failure: influence of pulmonary hypertension.
    Journal of the American College of Cardiology, 1993, Nov-01, Volume: 22, Issue:5

    Topics: Acetylcholine; Aged; Analysis of Variance; Case-Control Studies; Catheterization, Swan-Ganz; Chronic

1993
Increased production of nitric oxide in coronary arteries during congestive heart failure.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:1

    Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arginine; Atrial Natriuretic Factor; Azepines; Blood

1994
Impaired acetylcholine-mediated vasodilation in patients with congestive heart failure. Role of endothelium-derived vasodilating and vasoconstricting factors.
    Circulation, 1993, Volume: 88, Issue:1

    Topics: Acetylcholine; Cyclooxygenase Inhibitors; Endothelins; Female; Forearm; Heart Failure; Humans; Indom

1993
In utero congestive heart failure due to maternal indomethacin treatment for polyhydramnios and premature labour in a fetus with antenatal closure of the foramen ovale.
    Prenatal diagnosis, 1996, Volume: 16, Issue:7

    Topics: Adult; Autopsy; Female; Fetal Death; Heart Failure; Heart Septum; Humans; Indomethacin; Obstetric La

1996
Cardiac sympathetic afferent reflex in dogs with congestive heart failure.
    The American journal of physiology, 1996, Volume: 271, Issue:3 Pt 2

    Topics: Afferent Pathways; Animals; Blood Pressure; Bradykinin; Capsaicin; Dogs; Female; Heart Conduction Sy

1996
Impaired coronary sensitivity to diltiazem in experimental heart failure: involvement of the cyclooxygenase but not the nitric oxide-synthase pathway.
    Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:2

    Topics: Animals; Coronary Vessels; Cricetinae; Cyclooxygenase Inhibitors; Diltiazem; Enzyme Inhibitors; Hear

1996
Coronary and cardiac sensitivity to the vasoselective benzothiazepine-like calcium antagonist, clentiazem, in experimental heart failure.
    Cardiovascular drugs and therapy, 1997, Volume: 11, Issue:1

    Topics: Animals; Body Weight; Calcium Channel Blockers; Chronic Disease; Coronary Vessels; Cricetinae; Cyclo

1997
Indomethacin attenuates the renal actions of atrial natriuretic factor in dogs with chronic heart failure.
    The American journal of the medical sciences, 1997, Volume: 314, Issue:2

    Topics: Aldosterone; Animals; Arteriovenous Fistula; Atrial Natriuretic Factor; Chronic Disease; Creatinine;

1997
Altered vascular function in early stages of heart failure in hamsters.
    Journal of cardiac failure, 1997, Volume: 3, Issue:4

    Topics: Animals; Aorta; Cricetinae; Dose-Response Relationship, Drug; Endothelium, Vascular; Heart Failure;

1997
The contracted type of endocardial fibroelastosis.
    Clinical cardiology, 1999, Volume: 22, Issue:4

    Topics: Disease Progression; Ductus Arteriosus, Patent; Echocardiography; Endocardial Fibroelastosis; Fatal

1999
Enhanced acetylcholine and P2Y-receptor stimulated vascular EDHF-dilatation in congestive heart failure.
    Cardiovascular research, 1999, Volume: 43, Issue:1

    Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apamin; Biological Factors; C

1999
Augmented basal nitric oxide production contributes to maintenance of coronary blood flow in dogs with pacing-induced heart failure.
    Japanese heart journal, 1999, Volume: 40, Issue:5

    Topics: Animals; Cardiac Pacing, Artificial; Coronary Angiography; Coronary Circulation; Diastole; Dogs; Fem

1999
Intrarenal expression and distribution of cyclooxygenase isoforms in rats with experimental heart failure.
    American journal of physiology. Renal physiology, 2001, Volume: 280, Issue:1

    Topics: Animals; Arteriovenous Shunt, Surgical; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibit

2001
Acetylcholine-mediated vasodilation in the forearm circulation of patients with heart failure: indirect evidence for the role of endothelium-derived hyperpolarizing factor.
    The American journal of cardiology, 2001, May-01, Volume: 87, Issue:9

    Topics: Acetylcholine; Adult; Aged; Biological Factors; Brachial Artery; Case-Control Studies; Cyclooxygenas

2001
Compensated heart failure predisposes to outer medullary tubular injury: studies in rats.
    Kidney international, 2001, Volume: 60, Issue:2

    Topics: Acute Kidney Injury; Animals; Cardiomegaly; Cardiovascular Agents; Disease Models, Animal; Enzyme In

2001
Severe heart failure due to ductal constriction caused by maternal indomethacin.
    Pediatrics international : official journal of the Japan Pediatric Society, 2002, Volume: 44, Issue:2

    Topics: Adult; Constriction, Pathologic; Ductus Arteriosus; Female; Heart Failure; Humans; Indomethacin; Inf

2002
Plasma-prostaglandins in pre-term neonates before and after treatment for patient ductus arteriosus.
    Lancet (London, England), 1978, Jul-15, Volume: 2, Issue:8081

    Topics: Ductus Arteriosus, Patent; Heart Failure; Humans; Indomethacin; Infant, Newborn; Infant, Premature;

1978
Failure of indomethacin to close persistent ductus arteriosus in infants weighing under 1000 grams.
    British heart journal, 1979, Volume: 41, Issue:3

    Topics: Anuria; Digitalis Glycosides; Ductus Arteriosus, Patent; Female; Gastrointestinal Hemorrhage; Heart

1979
Pharmacokinetics/pharmacodynamics of furosemide in man: a review.
    Journal of pharmacokinetics and biopharmaceutics, 1979, Volume: 7, Issue:1

    Topics: Biological Availability; Dose-Response Relationship, Drug; Drug Interactions; Furosemide; Heart Fail

1979
Acute oliguric renal failure induced by indomethacin: possible mechanism.
    Annals of internal medicine, 1979, Volume: 91, Issue:1

    Topics: Acute Kidney Injury; Anuria; Female; Glomerular Filtration Rate; Heart Failure; Humans; Indomethacin

1979
Problem of patent ductus arteriosus in premature infants.
    Paediatrician, 1978, Volume: 7, Issue:1-3

    Topics: Animals; Aspirin; Blood Pressure; Coronary Circulation; Ductus Arteriosus, Patent; Heart Failure; He

1978
Increase in serum digoxin concentrations after indomethacin therapy in a full-term neonate.
    Pharmacotherapy, 1992, Volume: 12, Issue:4

    Topics: Creatinine; Digoxin; Drug Interactions; Ductus Arteriosus, Patent; Female; Heart Failure; Humans; In

1992
Renal response to indomethacin in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.
    The American journal of cardiology, 1992, Oct-01, Volume: 70, Issue:9

    Topics: Adult; Aged; Blood Pressure; Cardiomyopathy, Dilated; Coronary Disease; Female; Glomerular Filtratio

1992
Right ventricular concentric hypertrophy and left ventricular dilatation by ductal constriction in fetal rats.
    Circulation research, 1989, Volume: 64, Issue:6

    Topics: Animals; Cardiomegaly; Constriction, Pathologic; Dilatation, Pathologic; Ductus Arteriosus; Female;

1989
Prostaglandins, renin and atrial natriuretic peptide in the control of the circulation and renal function in heart failure in the dog.
    Progress in clinical and biological research, 1989, Volume: 301

    Topics: Animals; Atrial Natriuretic Factor; Dogs; Female; Heart Failure; Hemodynamics; Indomethacin; Kidney;

1989
Peripheral hemodynamic effects of captopril in patients with congestive heart failure.
    American heart journal, 1989, Volume: 117, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Bradykinin; Captopril; Dinoprostone; Female; Forearm; Hea

1989
Treatment of cardiac failure in infants.
    Comprehensive therapy, 1986, Volume: 12, Issue:2

    Topics: Alprostadil; Captopril; Digitalis Glycosides; Diuretics; Drug Therapy, Combination; Heart Failure; H

1986
Effects of captopril on peripheral hemodynamics in severe congestive heart failure.
    Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:2-3

    Topics: Blood Pressure; Captopril; Female; Forearm; Heart Failure; Hemodynamics; Hormones; Humans; Indometha

1987
Congestive heart failure due to nonsteroidal anti-inflammatory drugs in the elderly.
    Age and ageing, 1988, Volume: 17, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Heart Failure;

1988
Cardiovascular prostaglandins: some comments on their involvement in circulatory physiology and pathophysiology.
    Acta medica Scandinavica. Supplementum, 1986, Volume: 707

    Topics: 6-Ketoprostaglandin F1 alpha; Dinoprost; Dinoprostone; Epoprostenol; Heart Failure; Humans; Indometh

1986
Influence of heart failure and sodium content in the diet on the natriuretic response to furosemide in hamsters.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 50, Issue:2

    Topics: Animals; Arginine Vasopressin; Cardiomyopathy, Dilated; Cricetinae; Diet, Sodium-Restricted; Female;

1985
Nongouty crystal deposit arthritis.
    Modern treatment, 1971, Volume: 8, Issue:4

    Topics: Adrenocorticotropic Hormone; Aspirin; Bursitis; Chondrocalcinosis; Colchicine; Heart Failure; Humans

1971