Page last updated: 2024-10-29

indomethacin and HIV Coinfection

indomethacin has been researched along with HIV Coinfection in 14 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"The effects of indomethacin and naproxen on zidovudine (ZDV) pharmacokinetics were studied in six patients with the acquired immunodeficiency syndrome (AIDS), AIDS related complex (ARC) or asymptomatic HIV disease using a placebo-controlled crossover design."5.07The effects of indomethacin and naproxen on zidovudine pharmacokinetics. ( Back, D; Barry, M; Beeching, NJ; Breckenridge, A; Brettle, R; Howe, J; Mitchell, R; Nye, FJ, 1993)
"The causes of pruritus are numerous including xerosis, drug and photoeruptions, follicular and papular eruptions as well as infestations and infections by a wide range of organisms."2.68Pruritus in HIV-1 disease: therapy with drugs which may modulate the pattern of immune dysregulation. ( Lee, RB; Skelton, HG; Smith, KJ; Wagner, KF; Yeager, J, 1997)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (64.29)18.2507
2000's4 (28.57)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nomura, T1
Katoh, M1
Yamamoto, Y1
Miyachi, Y1
Kabashima, K1
Rivoisy, C1
Jauréguiberry, S1
M'Bappe, P1
Gibeault, M1
Bonnard, P1
Pialoux, G1
Johansson, CC1
Bryn, T1
Aandahl, EM1
Areklett, MA1
Aukrust, P1
Taskén, K1
Frøland, SS1
Longo, N1
Zabay, JM1
Sempere, JM1
Navarro, J1
Fernández-Cruz, E1
Barry, M1
Howe, J1
Back, D1
Breckenridge, A1
Brettle, R1
Mitchell, R1
Beeching, NJ1
Nye, FJ1
Chougnet, CA1
Margolis, D1
Landay, AL1
Kessler, HA1
Shearer, GM1
Bruguera, M1
Smith, KJ2
Skelton, HG2
Yeager, J1
Lee, RB1
Wagner, KF1
Marshall, JD1
Robertson, SE1
Trinchieri, G1
Chehimi, J1
Giacomini, E1
Giordani, L1
di Modugno, F1
Chersi, A1
Luzzati, AL1
Walker, UA1
Venhoff, N1
Hadden, JW1
Ongradi, J1
Specter, S1
Nelson, R1
Sosa, M1
Monell, C1
Strand, M1
Giner-Sorolla, A1
Hadden, EM1
Edelman, AS1
Zolla-Pazner, S1

Reviews

2 reviews available for indomethacin and HIV Coinfection

ArticleYear
Eosinophilic pustular folliculitis: A published work-based comprehensive analysis of therapeutic responsiveness.
    The Journal of dermatology, 2016, Volume: 43, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Drugs, Chinese Herbal; Eosino

2016
[Treatment of chronic hepatitis C: still many problems pending].
    Gastroenterologia y hepatologia, 1997, Volume: 20, Issue:1

    Topics: Adrenal Cortex Hormones; Aged; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antiv

1997

Trials

3 trials available for indomethacin and HIV Coinfection

ArticleYear
Treatment with type-2 selective and non-selective cyclooxygenase inhibitors improves T-cell proliferation in HIV-infected patients on highly active antiretroviral therapy.
    AIDS (London, England), 2004, Apr-09, Volume: 18, Issue:6

    Topics: Adult; Antiretroviral Therapy, Highly Active; Cell Division; Cyclooxygenase Inhibitors; Female; HIV

2004
The effects of indomethacin and naproxen on zidovudine pharmacokinetics.
    British journal of clinical pharmacology, 1993, Volume: 36, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Female; Glucuronates; HIV Infections; Humans; Indomethaci

1993
Pruritus in HIV-1 disease: therapy with drugs which may modulate the pattern of immune dysregulation.
    Dermatology (Basel, Switzerland), 1997, Volume: 195, Issue:4

    Topics: Administration, Cutaneous; Administration, Topical; Anti-Inflammatory Agents; Antipruritics; Cycloox

1997

Other Studies

9 other studies available for indomethacin and HIV Coinfection

ArticleYear
Tenosynovitis as a possible feature of immune reconstitution syndrome during highly active antiretroviral treatment (HAART).
    Joint bone spine, 2009, Volume: 76, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Inflammatory Agents, Non-Steroidal; Antire

2009
Altered production of PGE2, IL-1 beta and TNF-alpha by peripheral blood monocytes from HIV-positive individuals at early stages of HIV infection.
    Journal of acquired immune deficiency syndromes, 1993, Volume: 6, Issue:9

    Topics: Cells, Cultured; Chi-Square Distribution; Dinoprostone; HIV Infections; Humans; Indomethacin; Interl

1993
Contribution of prostaglandin E2 to the interleukin-12 defect in HIV-infected patients.
    AIDS (London, England), 1996, Volume: 10, Issue:9

    Topics: Dinoprostone; HIV Infections; HIV-1; Humans; Indomethacin; Interleukin-2; Leukocytes, Mononuclear

1996
Priming with IL-4 and IL-13 during HIV-1 infection restores in vitro IL-12 production by mononuclear cells of HIV-infected patients.
    Journal of immunology (Baltimore, Md. : 1950), 1997, Dec-01, Volume: 159, Issue:11

    Topics: HIV Infections; Humans; Indomethacin; Interleukin-10; Interleukin-12; Interleukin-13; Interleukin-4;

1997
Increased PGE2 production mediates the in vitro inhibitory effect of the human immunodeficiency virus P24 immunosuppressive heptapeptide Ch7.
    Scandinavian journal of immunology, 1998, Volume: 48, Issue:3

    Topics: Antibody Formation; Antibody-Producing Cells; Dinoprostone; HIV Core Protein p24; HIV Infections; Hu

1998
Peroxisomal proliferator-activated ligand therapy for HIV lipodystrophy.
    Clinical and experimental dermatology, 2001, Volume: 26, Issue:2

    Topics: Anti-HIV Agents; Cyclooxygenase Inhibitors; Dehydroepiandrosterone; Drug Therapy, Combination; HIV I

2001
Multiple mitochondrial DNA deletions and lactic acidosis in an HIV-infected patient under antiretroviral therapy.
    AIDS (London, England), 2001, Jul-27, Volume: 15, Issue:11

    Topics: Acidosis, Lactic; Anti-HIV Agents; Cell Line; DNA, Mitochondrial; Drug Therapy, Combination; Enzyme

2001
Methyl inosine monophosphate: a potential immunotherapeutic for early human immunodeficiency virus (HIV) infection.
    International journal of immunopharmacology, 1992, Volume: 14, Issue:4

    Topics: Adjuvants, Immunologic; Adult; Animals; Female; Friend murine leukemia virus; HIV Infections; Humans

1992
Proliferative response of mononuclear cells from HIV-infected patients to B-cell mitogens: effects of lymphocyte subset frequency, T-cell defects and prostaglandins.
    AIDS research and human retroviruses, 1991, Volume: 7, Issue:11

    Topics: B-Lymphocytes; Growth Substances; HIV Infections; Humans; Indomethacin; Leukocyte Count; Lymphocyte

1991