indomethacin has been researched along with Group A Strep Infection in 32 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The comparative effect of indomethacin and hydrocortisone on the resistance of mice or rats to various acute, subacute, and latent bacterial infections was investigated." | 7.64 | Effects of indomethacin on acute, subacute, and latent infections in mice and rats. ( Graessle, OE; Phares, HF; Robinson, HJ, 1968) |
| " Because blockade of prostaglandin H synthase (cyclooxygenase) with indomethacin prevents GBS-induced pulmonary hypertension, we reasoned that the salutary effect of indomethacin might be associated with a reduction in the efficacy of bactericidal activity directed against GBS." | 3.68 | Impact of prostaglandin and thromboxane synthesis blockade on disposition of group B streptococcus in lung and liver of intact piglet. ( Aziz, SM; Gillespie, MN; Horstman, SJ; Pauly, TH, 1992) |
| "The comparative effect of indomethacin and hydrocortisone on the resistance of mice or rats to various acute, subacute, and latent bacterial infections was investigated." | 3.64 | Effects of indomethacin on acute, subacute, and latent infections in mice and rats. ( Graessle, OE; Phares, HF; Robinson, HJ, 1968) |
| "The issue related with acute rheumatic fever still remains to be topical at the present stage, which is accentuated by a high prevalence of rheumatic heart diseases." | 2.42 | [Acute rheumatic fever: problems and outlooks]. ( Belov, BS, 2003) |
| "To report a case with reactive arthritis (ReA) following Streptococcus viridans genitourinary infection." | 1.36 | Reactive arthritis following Streptococcus viridans urinary tract infection. ( Chen, JT; Chou, YS; Horng, CT; Hu, SC; Huang, HS; Tsai, ML, 2010) |
| " In this model no effect of the receptor site antagonist was noted, but due to the short half-life of this compound, a different dosing schedule may be needed before its efficacy can be determined." | 1.27 | Group B streptococcal (GBSS) newborn septic shock model: the role of prostaglandins. ( Miller, MK; Pan, J; Short, BL, 1988) |
| " After establishing a dose-response relationship, we chose a control dose that produced intermediate hypertensive responses." | 1.27 | Hemodynamic responses of chronically instrumented piglets to bolus injections of group B streptococci. ( Barefield, E; Godoy, G; Gray, BM; Graybar, G; Lyrene, RK; Philips, JB; Sams, JE, 1988) |
| "Ibuprofen was more effective than indomethacin in the high mortality model (lethal dose for 90% survival of group)." | 1.26 | Improved survival in the suckling rat model of group B streptococcal sepsis after treatment with nonsteroidal anti-inflammatory drugs. ( Fletcher, JR; Miller, MK; Short, BL, 1982) |
| "Every form of glomerulonephritis has in all probability its individual course and prognosis, which can only be very slightly influenced by therapy." | 1.26 | The morphological and clinical course of the different forms of glomerulonephritis. ( Bohle, A; Edel, HH; Fishbach, H; Frotscher, U; Kluthe, R; Meyer, D; Renner, D; Rinsche, K; Scheler, F, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (62.50) | 18.7374 |
| 1990's | 5 (15.63) | 18.2507 |
| 2000's | 4 (12.50) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Emeruwa, UN | 1 |
| Krenitsky, NM | 1 |
| Sheen, JJ | 1 |
| Ernst, W | 1 |
| Zimara, N | 1 |
| Hanses, F | 1 |
| Männel, DN | 1 |
| Seelbach-Göbel, B | 1 |
| Wege, AK | 1 |
| Nögel, SC | 1 |
| Chada, M | 1 |
| Schmidt, AM | 1 |
| Bosselmann, S | 1 |
| Kandler, M | 1 |
| Schweer, H | 1 |
| Watzer, B | 1 |
| Schneider, H | 1 |
| Gessner, A | 1 |
| Rascher, W | 1 |
| Chou, YS | 1 |
| Horng, CT | 1 |
| Huang, HS | 1 |
| Hu, SC | 1 |
| Chen, JT | 1 |
| Tsai, ML | 1 |
| Belov, BS | 1 |
| Short, BL | 3 |
| Miller, MK | 3 |
| Stroud, CY | 1 |
| Fletcher, JR | 2 |
| Hemming, VG | 1 |
| O'Brien, WF | 1 |
| Fischer, GW | 1 |
| Golden, SM | 1 |
| Noble, SF | 1 |
| Runkle, B | 1 |
| Goldberg, RN | 2 |
| Streitfeld, MM | 1 |
| Clark, MR | 1 |
| Buron, E | 1 |
| Setzer, ES | 1 |
| Bancalari, E | 2 |
| Cherry, JD | 1 |
| Barrett, CT | 1 |
| O'Meara, ME | 1 |
| Eknoyan, G | 1 |
| Murphy, TD | 1 |
| Gibson, RL | 2 |
| Standaert, TA | 1 |
| Woodrum, DE | 1 |
| Rudinsky, BF | 1 |
| Lozon, M | 2 |
| Bell, A | 2 |
| Hipps, R | 2 |
| Meadow, WL | 1 |
| Bethea, CL | 1 |
| Gravett, MG | 1 |
| Sadowsky, DW | 1 |
| Haluska, GJ | 1 |
| Axthelm, MK | 1 |
| Novy, MJ | 1 |
| Axethelm, MK | 1 |
| Rudinsky, B | 1 |
| Meadow, W | 1 |
| Hui, JY | 1 |
| Woo, PC | 1 |
| Lo, SS | 1 |
| Chan, JC | 1 |
| Levison, SP | 2 |
| Levison, ME | 2 |
| Pitsakis, P | 1 |
| Fishbach, H | 1 |
| Bohle, A | 1 |
| Meyer, D | 1 |
| Edel, HH | 1 |
| Frotscher, U | 1 |
| Kluthe, R | 1 |
| Renner, D | 1 |
| Rinsche, K | 1 |
| Scheler, F | 1 |
| Truog, WE | 1 |
| Henderson, WR | 1 |
| Redding, GJ | 1 |
| Pauly, TH | 1 |
| Aziz, SM | 1 |
| Horstman, SJ | 1 |
| Gillespie, MN | 1 |
| Peevy, KJ | 1 |
| Panus, P | 1 |
| Longenecker, GL | 1 |
| Chartrand, SA | 1 |
| Wiseman, HJ | 1 |
| Boerth, RC | 1 |
| Olson, RD | 1 |
| Suguihara, C | 1 |
| Hehre, D | 1 |
| Bancalari, A | 1 |
| Pan, J | 1 |
| Philips, JB | 2 |
| Lyrene, RK | 2 |
| Godoy, G | 1 |
| Graybar, G | 1 |
| Barefield, E | 1 |
| Sams, JE | 1 |
| Gray, BM | 2 |
| Huddleston, KW | 1 |
| Dew, A | 1 |
| Muir, SK | 1 |
| Kinsella, PL | 1 |
| Trebilcock, RG | 1 |
| Blackstone, IW | 1 |
| Kahn, MF | 1 |
| Stambolović, B | 1 |
| Velimirović, D | 1 |
| Suc, JM | 1 |
| Conte, J | 1 |
| Ruggieri, G | 1 |
| Robinson, HJ | 1 |
| Phares, HF | 1 |
| Graessle, OE | 1 |
2 reviews available for indomethacin and Group A Strep Infection
| Article | Year |
|---|---|
Advances in Management for Preterm Fetuses at Risk of Delivery.
Topics: Anti-Bacterial Agents; Anticonvulsants; Betamethasone; Dexamethasone; Female; Fetal Membranes, Prema | 2020 |
[Acute rheumatic fever: problems and outlooks].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non- | 2003 |
30 other studies available for indomethacin and Group A Strep Infection
| Article | Year |
|---|---|
Humanized mice, a new model to study the influence of drug treatment on neonatal sepsis.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Load; Betamethason | 2013 |
Parecoxib does not suppress thromboxane synthesis in newborn piglets with group B streptococcal sepsis.
Topics: Animals; Animals, Newborn; Cyclooxygenase 2 Inhibitors; Dinoprostone; Epoprostenol; Gene Expression | 2009 |
Reactive arthritis following Streptococcus viridans urinary tract infection.
Topics: Adult; Arthritis, Reactive; Behcet Syndrome; Clindamycin; Humans; Indomethacin; Male; Prohibitins; S | 2010 |
Comparison of thromboxane inhibitors to cyclooxygenase inhibitors on survival in a newborn rat model for group B streptococcal sepsis.
Topics: Animals; Animals, Newborn; Ibuprofen; Indomethacin; Rats; Rats, Inbred Strains; Sepsis; Streptococca | 1983 |
Studies of short-term pulmonary and peripheral vascular responses induced in oophorectomized sheep by the infusion of a group B streptococcal extract.
Topics: Animals; Blood Pressure; Castration; Endotoxins; Escherichia coli; Female; Femoral Artery; Hypertens | 1984 |
Cardiovascular changes in group B streptococcal sepsis in the piglet: response to indomethacin and relationship to prostacyclin and thromboxane A2.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cardiac Output; Epoprostenol; Hemodynamics; I | 1984 |
Improved survival in the suckling rat model of group B streptococcal sepsis after treatment with nonsteroidal anti-inflammatory drugs.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Humans; Ibuprofen; Indomethacin; Infant, Newborn; | 1982 |
Nonsteroidal anti-inflammatory drugs and the treatment of neonatal sepsis due to group B streptococci.
Topics: Animals; Anti-Inflammatory Agents; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; | 1982 |
Acute renal failure associated with indomethacin administration.
Topics: Acute Kidney Injury; Adult; Arthritis, Infectious; Endocarditis, Bacterial; Female; Humans; Indometh | 1980 |
Diaphragmatic failure during group B streptococcal sepsis in piglets: the role of thromboxane A2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Gas Analysis; Bri | 1995 |
Group B streptococcal sepsis impairs cerebral vascular reactivity to acute hypercarbia in piglets.
Topics: Animals; Blood Pressure; Brain; Carbon Monoxide; Carotid Artery, Internal; Disease Models, Animal; H | 1996 |
Amniotic fluid prolactin is decreased by experimental intrauterine infection or interleukin-1beta infusion but not via prostaglandins in pregnant rhesus macaques.
Topics: Amnion; Amniotic Fluid; Animals; Chorioamnionitis; Chorion; Decidua; Female; Indomethacin; Interleuk | 1998 |
Hemodynamic homeostasis during acute hypoxia in septic and nonseptic piglets: differential role of prostaglandins and nitric oxide.
Topics: Animals; Arginine; Hemodynamics; Homeostasis; Hypoxia; Indomethacin; Nitric Oxide; Prostaglandin Ant | 2000 |
Over-the-counter medication and its effects.
Topics: Abscess; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cushing Syndrome; | 2002 |
Papillary plasma flow in experimental pyelonephritis in rats: effect of antibiotic therapy and indomethacin.
Topics: Ampicillin; Animals; Indomethacin; Kidney; Male; Osmolar Concentration; Pyelonephritis; Rats; Region | 1978 |
Effect of indomethacin and sodium meclofenamate on the renal concentrating defect in experimental enterococcal pyelonephritis in rats.
Topics: Animals; Indomethacin; Kidney Concentrating Ability; Male; Meclofenamic Acid; ortho-Aminobenzoates; | 1976 |
The morphological and clinical course of the different forms of glomerulonephritis.
Topics: Acute Disease; Antimetabolites; Glomerulonephritis; Humans; Indomethacin; Male; Middle Aged; Necrosi | 1976 |
Group B streptococcal sepsis in piglets: effect of combined pentoxifylline and indomethacin pretreatment.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Drug Therapy, Combination; Hemodynamics; Indometh | 1992 |
Impact of prostaglandin and thromboxane synthesis blockade on disposition of group B streptococcus in lung and liver of intact piglet.
Topics: Animals; Free Radicals; Hypertension, Pulmonary; Indomethacin; Liver; Lung; Methacrylates; Prostagla | 1992 |
Prostaglandin synthetase inhibition in group B streptococcal shock: hematologic and hemodynamic effects.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bicarbonates; Blood Gas Analysis; Blood Platelets; Blood Pres | 1986 |
Effect of cyclooxygenase and lipoxygenase products on pulmonary function in group B streptococcal sepsis.
Topics: Animals; Blood Pressure; Chromones; Cyclooxygenase Inhibitors; Indomethacin; Lung; Lung Compliance; | 1987 |
Group B streptococcal (GBSS) newborn septic shock model: the role of prostaglandins.
Topics: Animals; Animals, Newborn; Blood Glucose; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, | 1988 |
Hemodynamic responses of chronically instrumented piglets to bolus injections of group B streptococci.
Topics: Animals; Antibodies, Bacterial; Female; Hemodynamics; Hypertension, Pulmonary; Imidazoles; Indometha | 1988 |
Influence of prostaglandin D2 on hemodynamic effects of group B streptococcus in neonatal lambs.
Topics: Animals; Animals, Newborn; Blood Pressure; Hemodynamics; Hypertension, Pulmonary; Indomethacin; Pros | 1986 |
Infectious arthritis of the sternoclavicular joint.
Topics: Arthritis, Infectious; Cloxacillin; Humans; Indomethacin; Male; Middle Aged; Penicillins; Staphyloco | 1985 |
[The treatment of chronic inflammatory rheumatism].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin; Co | 1973 |
[Diagnosis and treatment of rheumatic disorders in the pelvis].
Topics: Antistreptolysin; Blood Sedimentation; Female; Fibromyalgia; Focal Infection; Humans; Indomethacin; | 1974 |
Treatment of glomerulonephritis with indomethacin and heparin.
Topics: Adolescent; Adult; Aged; Child; Female; Glomerulonephritis; Heparin; Humans; Hypersensitivity; Indom | 1973 |
[Therapy of rheumatic carditis].
Topics: Adrenal Cortex Hormones; Aminopyrine; Anti-Bacterial Agents; Humans; Immunoglobulins; Indomethacin; | 1971 |
Effects of indomethacin on acute, subacute, and latent infections in mice and rats.
Topics: Acute Disease; Animals; Corynebacterium; Female; Hydrocortisone; Indomethacin; Infections; Klebsiell | 1968 |